140,810 results match your criteria Foot and Ankle Surgery [Journal]


Overview of Metatarsalgia.

Orthopedics 2018 Dec 11:1-6. Epub 2018 Dec 11.

Metatarsalgia can be viewed as more of a symptom rather than a distinct diagnosis. Timing of forefoot pain during the gait cycle and evaluation of whether the pain is from anatomic abnormalities, indirect overloading, or iatrogenic causes can suggest a specific metatarsalgia etiology. A thorough physical examination of the lower extremity, especially evaluation of the plantar foot, and weight-bearing radiographs are critical for diagnosis and treatment. Read More

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December 2018

Adherence to quality of care measurements among 58,182 patients with new onset diabetes and its association with mortality.

PLoS One 2018 12;13(12):e0208539. Epub 2018 Dec 12.

The Department of Family Medicine, The Sackler Faculty of Medicine, University of Tel Aviv, Tel-Aviv, Israel.

Objectives: Disease registry for diabetes care encourages transparency and benchmarking of quality of care (QoC) measurements for all service providers and seems to improve diabetes care. This study evaluate changes over time in QoC measurement performance in a large diabetes registry among newly diagnosed diabetics and it association with mortality.

Methods: Retrospective cohort study of patients in a large health maintenance organization diabetes registry from years 2000 to 2013. Read More

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December 2018
1 Read

Loading of the hip and knee joints during whole body vibration training.

PLoS One 2018 12;13(12):e0207014. Epub 2018 Dec 12.

Julius Wolff Institute, Charité - Universitätsmedizin Berlin, Berlin, Germany.

During whole body vibrations, the total contact force in knee and hip joints consists of a static component plus the vibration-induced dynamic component. In two different cohorts, these forces were measured with instrumented joint implants at different vibration frequencies and amplitudes. For three standing positions on two platforms, the dynamic forces were compared to the static forces, and the total forces were related to the peak forces during walking. Read More

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December 2018

Calendar for December Issue.

Authors:

Foot Ankle Spec 2018 Dec;11(6):565-567

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December 2018

Dance Functional Outcome Survey: Development and Preliminary Analyses.

Sports Med Int Open 2018 Nov 28;2(6):E191-E199. Epub 2018 Nov 28.

ADAM Center, New York, NY United States.

The Dance Functional Outcome Survey (DFOS) was developed as a self-report questionnaire for healthy and injured ballet and modern dancers, focusing on the low back and lower extremities. Our aim was to determine factor analysis and internal consistency of the 16 items and to investigate test-retest and equivalence reliability and validity of the DFOS compared to three orthopedic outcomes instruments. Data were collected from 80 healthy and injured adult ballet and modern pre-professional and professional dancers. Read More

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November 2018

High EIF2B5 mRNA expression and its prognostic significance in liver cancer: a study based on the TCGA and GEO database.

Cancer Manag Res 2018 20;10:6003-6014. Epub 2018 Nov 20.

Department of Hepatobiliary and Pancreatic Surgery, The First Hospital of Jilin University, Changchun, Jilin 130021, People's Republic of China,

Purpose: Liver cancer is a high mortality disease with no curable treatments. Posttranscriptional modifications play essential roles in the occurrence and the progression of liver cancer. EIF2B5 is a subunit of EIF2B that regulates the initiation and the rate of translation and participates in several diseases including tumors. Read More

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November 2018

Effectiveness of pharmacist-led educational interventions on self-care activities and glycemic control of type 2 diabetes patients: a systematic review and meta-analysis.

Patient Prefer Adherence 2018 21;12:2457-2474. Epub 2018 Nov 21.

School of Pharmacy, Monash University Malaysia, Selangor 47500, Malaysia,

Background: Effectiveness of pharmacist-led educational interventions on self-care activities and glycemic control of type 2 diabetes mellitus (T2DM) patients is vague. The purpose of this review is to appraise the effect of pharmacist-led educational interventions on self-care activities and levels of glycated hemoglobin of T2DM patients.

Methods: Five electronic databases were searched from date of database inception to September 2017. Read More

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November 2018

ERα PvuII and XbaI polymorphisms in postmenopausal women with posterior tibial tendon dysfunction: a case control study.

J Orthop Surg Res 2018 Dec 11;13(1):316. Epub 2018 Dec 11.

Department of Orthopaedic and Traumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

Background: Posterior tibial tendon (PTT) insufficiency is considered as the main cause of adult acquired flat foot and is three times more frequent in females. High estrogen levels exert a positive effect on the overall collagen synthesis in tendons. We have previously demonstrated the association between some genetic single-nucleotide polymorphism (SNP) and tendinopathy. Read More

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December 2018

Angioplasty and stenting for below the knee ulcers in diabetic patients: protocol for a systematic review.

Syst Rev 2018 Dec 11;7(1):228. Epub 2018 Dec 11.

Division of Vascular and Endovascular Surgery, Department of Surgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Borges Lagoa 754, São Paulo, 04038-001, SP, Brazil.

Background: The worldwide incidence and prevalence of diabetes mellitus (DM) are increasing. DM has a high social and economic burden due to its complications and associated disorders. Peripheral arterial disease (PAD) is closely related to DM. Read More

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December 2018

Renal Function as a Predictor of Early Transmetatarsal Amputation Failure.

Foot Ankle Spec 2018 Dec 12:1938640018816371. Epub 2018 Dec 12.

Department of Orthopaedic Surgery (JA, KMR, GTL, DKW), University of Texas Southwestern Medical Center, Dallas, Texas.

Chronic kidney disease (CKD) is a major concern in patients with foot disease because it is associated with high rates of neuropathy, peripheral vascular disease, and poor wound healing. The purpose of this study was to evaluate renal dysfunction as a risk factor for reamputation after initial transmetatarsal amputation (TMA). Patients who underwent a TMA were retrospectively identified in the American College of Surgeons National Surgical Quality Improvement Program database. Read More

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December 2018

The case of successful catheter ablation using only the approach from the upper part of the subject's body, with meandering aorta and implanted IVC filter.

J Cardiol Cases 2011 Oct 19;4(2):e115-e120. Epub 2011 Aug 19.

Second Department of Internal Medicine, Kansai Medical University, Moriguchi City, Japan.

A 79-year-old female had paroxysmal supraventricular tachycardia. However, she was implanted with an inferior vena cava filter and her descending aorta had significant meandering. It was thought that the insertion of the catheters would be difficult from the femoral vessels. Read More

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October 2011

[Acute Motor Failure of the N. Peroneus Profundus Caused by a Cystic Tibiofibular Joint].

Z Orthop Unfall 2018 Dec 11. Epub 2018 Dec 11.

Orthopädie und Traumatologie, Bürgerspital Solothurn, Solothurn, Schweiz.

A ganglion cyst is rarely the cause of peripheral nerve compression. In the lower extremity, it is important to distinguish clinically the symptoms from a radiculopathy. In the literature, neural damage of the peroneal nerve due to a ganglion cyst has been described. Read More

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December 2018
2 Reads

Type I Interferons: Distinct Biological Activities and Current Applications for Viral Infection.

Cell Physiol Biochem 2018 11;51(5):2377-2396. Epub 2018 Dec 11.

State Key Laboratory of Veterinary Etiological Biology, OIE/National Foot-and-Mouth Disease Reference Laboratory, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou,

The interferons (IFNs) are a primary defense against pathogens because of the strong antiviral activities they induce. IFNs can be classified into three groups: type I, type II and type III, according to their genetic, structural, and functional characteristics and their receptors on the cell surface. The type I IFNs are the largest group and include IFN-α, IFN-β, IFN-ε, IFN-ω, IFN-κ, IFN-δ, IFN-τ and IFN-ζ. Read More

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December 2018

Resveratrol attenuates the MSU crystal-induced inflammatory response through the inhibition of TAK1 activity.

Int Immunopharmacol 2018 Dec 7;67:62-68. Epub 2018 Dec 7.

Institute of Rheumatology and Immunology, The Affiliated Hospital of North Sichuan Medical College, 63# Wenhua Road, Nanchong 637000, Sichuan, China; Sichuan Key Laboratory of Medical Imaging, North SiChuan Medical College, 234# Fujiang Road, Nanchong 637000, Sichuan, China; Preclinical School of North SiChuan Medical College, 234# Fujiang Road, Nanchong 637000, Sichuan, China. Electronic address:

TAK1 is closely associated with the NF-κB and MAPK signaling pathways. In the present study, we aimed to explore the relationship between TAK1 and gout as well as the effects of resveratrol on TAK1 activity and MSU crystal-induced inflammation. The expression levels of total TAK1 and phosphorylated TAK1 in gout patients were detected by western blotting. Read More

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December 2018
1 Read

Hind- and Midfoot Bone Morphology Varies with Foot Type and Sex.

J Orthop Res 2018 Dec 11. Epub 2018 Dec 11.

RR&D Center for Limb Loss and MoBility, VA Puget Sound, Seattle, WA.

Foot type has been associated with pain, injury, and altered gait mechanics. Morphological variations in foot bones due to foot type variation may impact surgical and therapeutic treatments. The purpose of this study was to utilize principal component analysis (PCA) to determine how morphology of the hind- and midfoot bones differs among foot types and sex. Read More

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December 2018

A NEW COMPREHENSIVE PROCEDURE FOR CUSTOM-MADE TOTAL ANKLE REPLACEMENTS: MEDICAL IMAGING, JOINT MODELING, PROSTHESIS DESIGN, AND 3D PRINTING.

J Orthop Res 2018 Dec 11. Epub 2018 Dec 11.

Movement Analysis Laboratory, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.

Many failures in total joint replacement are associated to prosthesis-to-bone mismatch. With recent additive-manufacturing, i.e. Read More

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December 2018

Angioplasty versus stenting for infrapopliteal arterial lesions in chronic limb-threatening ischaemia.

Cochrane Database Syst Rev 2018 Dec 8;12:CD009195. Epub 2018 Dec 8.

Department of Medical Imaging, Gold Coast University Hospital, 1 Hospital Blvd, Southport, Queensland, Australia, 4215.

Background: Chronic limb-threatening ischaemia (CLTI) is a manifestation of peripheral arterial disease (PAD) that includes chronic ischaemic rest pain or ischaemic skin lesions, ulcers, or gangrene for longer than two weeks. The severity of the disease depends on the extent of arterial stenosis and the availability of collateral circulation. Treatment for CLTI aims to relieve ischaemic pain, heal ischaemic ulcers, prevent limb loss, improve quality of life, and prolong survival. Read More

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December 2018
1 Read

Case of hand, foot and mouth disease with vesicular Koebner phenomenon on the ankles caused by Coxsackievirus A6 in an adult.

J Dermatol 2018 Dec 10. Epub 2018 Dec 10.

Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.

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December 2018

Identifying the Emergence of the Superficial Peroneal Nerve through Deep Fascia on Ultrasound and by Dissection: Implications for Regional Anaesthesia in Foot and Ankle Surgery.

Clin Anat 2018 Dec 10. Epub 2018 Dec 10.

School of Medicine, University of St Andrews, UK.

Regional anesthesia relies on a sound understanding of anatomy and the utility of ultrasound in identifying relevant structures. We assessed the ability to identify the point at which the superficial peroneal nerve (SPN) emerges through the deep fascia by ultrasound on 26 volunteers (mean age 27.85 years ±13. Read More

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December 2018
4 Reads

Tc-Ceftizoxime: Synthesis, characterization and its use in diagnosis of diabetic foot osteomyelitis.

J Med Imaging Radiat Oncol 2018 Dec 10. Epub 2018 Dec 10.

Department of Nuclear Medicine, Nuclear Medicine, Oncology and Radiotherapy Institute (NORI), Islamabad, Pakistan.

Introduction: The diagnosis of diabetic foot osteomyelitis is crucial and challenging for the proper management of diabetic foot. Tc labelled Ceftizoxime was used as a non-invasive diagnostic agent for diabetic foot osteomyelitis.

Methods: Ceftizoxime [CFT], a third generation cephalosporin, was used in a simple and direct method for the synthesis of TcO labelled infection imaging agent with stannous chloride as reducing agent. Read More

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December 2018
1 Read

The lysyl oxidase like 2/3 enzymatic inhibitor, PXS-5153A, reduces crosslinks and ameliorates fibrosis.

J Cell Mol Med 2018 Dec 9. Epub 2018 Dec 9.

Drug Discovery department, Pharmaxis Ltd., Sydney, NSW, Australia.

Fibrosis is characterized by the excessive deposition of extracellular matrix and crosslinked proteins, in particular collagen and elastin, leading to tissue stiffening and disrupted organ function. Lysyl oxidases are key players during this process, as they initiate collagen crosslinking through the oxidation of the ε-amino group of lysine or hydroxylysine on collagen side-chains, which subsequently dimerize to form immature, or trimerize to form mature, collagen crosslinks. The role of LOXL2 in fibrosis and cancer is well documented, however the specific enzymatic function of LOXL2 and LOXL3 during disease is less clear. Read More

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December 2018
1 Read

Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement.

Int Urol Nephrol 2018 Dec 7. Epub 2018 Dec 7.

Department of Endocrinology, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Chongqing, 400038, China.

Purpose: To assess the role of serum pigment epithelium-derived factor (PEDF) in the occurrence and development of proteinuria and renal dysfunction and determine its relevant signaling pathway.

Methods: We analyzed serum PEDF, creatinine, the urinary albumin-to-creatinine ratio, and renal morphology of normal or streptozotocin (STZ)-induced diabetic mice, before and after treatment with PEDF. In vitro, podocytes were stimulated with PEDF under normal or high-glucose conditions; permeability was measured by the transwell assay with fluorescein isothiocyanate (FITC)-dextran; and F-actin cytoskeleton was analyzed by phalloidin staining. Read More

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December 2018
1 Read
1.293 Impact Factor

Detection of Antibodies Against Foot-and-Mouth Disease Virus Serotypes A, O and Asia-1 by ELISA in Strip-Dried Samples from Vaccinated Bovines.

Appl Biochem Biotechnol 2018 Dec 10. Epub 2018 Dec 10.

Federal Centre for Animal Health, Vladimir, Russia, 600901.

Antibodies against foot-and-mouth disease virus serotypes A, O and Asia-1 were detected by ELISA in liquid and strip-dried samples from vaccinated bovines. The results showed high concordance of the results in both types of serum samples (coefficient of correlation varied from 0.89 to 0. Read More

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December 2018

A phase II trial of the effect of perindopril on hand-foot skin reaction (HFSR) incidence and severity in patients receiving regorafenib for refractory mCRC.

Cancer Chemother Pharmacol 2018 Dec 8. Epub 2018 Dec 8.

BC Cancer Vancouver Centre, 600-10th Ave W, Vancouver, BC, V5Z 4E6, Canada.

Purpose: Regorafenib is an oral multi-kinase inhibitor that offers an OS benefit to patients with mCRC refractory to standard therapy (Grothey et al., in Lancet 381:303-312, 2013), but comes with potential significant toxicities including grade 3 hand-foot skin reaction (HFSR). The pathogenesis of regorafenib-induced HFSR is not well established, but may be related to alterations in the capillary endothelium. Read More

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December 2018
2 Reads

Safety and efficacy of trastuzumab administered as a 30-min infusion in patients with HER2-positive advanced gastric cancer.

Cancer Chemother Pharmacol 2018 Dec 8. Epub 2018 Dec 8.

CELLTRION Healthcare Co. Ltd, Incheon, Republic of Korea.

Purpose: To investigate the safety and efficacy of 30-min maintenance infusions of trastuzumab in advanced gastric cancer positive for human epidermal growth factor receptor 2 (HER2).

Methods: This was a retrospective study conducted across five Korean hospitals in patients with HER2-positive gastric or gastroesophageal junction adenocarcinoma treated with first-line, 3-weekly trastuzumab plus chemotherapy. The first dose of trastuzumab (8 mg/kg) was administered as a 90-min infusion, with all subsequent maintenance infusions (6 mg/kg) given over 30 min. Read More

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December 2018

Evaluating the Medial Longitudinal Arch of the Foot: Correlations, Reliability, and Accuracy in People With a Low Arch.

Phys Ther 2018 Dec 7. Epub 2018 Dec 7.

Department of Physiotherapy, Faculty of Medicine, Espinardo Campus, University of Murcia, Murcia, Spain.

Background: The medial longitudinal arch of the foot is a variable structure, and a decrease in its height could affect several functions and increase the risk of injuries in the lower limbs. There are many different techniques for evaluating it.

Objective: The objective of this study was to evaluate the correlations of the Navicular Drop Test, several footprint parameters, and the Foot Posture Index-6 in people with a low medial longitudinal arch. Read More

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December 2018

[Frequency of Epidermophyton floccosum in isolated dermatophytea laboratory from the Region of Valparaiso, Chile. Time frame: 1990-2010].

Rev Chilena Infectol 2018 ;35(3):262-265

Laboratorio de Micología, Universidad de Valparaíso, Valparaíso, Chile.

Background: Dermatophytoses are frequent infections in human, which are produced by fungus genera Trichophyton, Microsporum and Epidermophyton.

Aim: To determine frequency of E. floccosum in isolated dermatophyte in a laboratory from Valparaíso during the last three decades, in addition to knowing the most frequent localization, age and gender of patients affected by this agent. Read More

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January 2018

Diabetic foot - epidemiological and histopathological aspects.

Rom J Morphol Embryol 2018 ;59(3):895-902

Department of Physiopathology, Faculty of Medicine, "Titu Maiorescu" University, Bucharest, Romania; Department of Family Medicine, University of Medicine and Pharmacy of Craiova, Romania;

Our study included a total of 259 patients with diabetes, who were admitted to the Department of Plastic Surgery and Reconstructive Microsurgery of the Emergency County Hospital of Piteşti, Romania, in 2016, with the diagnosis of "diabetic foot". Of the 259 patients, 55 (21.23%) were diagnosed with type 1 diabetes, and the remaining 204 (78. Read More

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January 2018

Histopathological changes in major amputations due to diabetic foot - a review.

Rom J Morphol Embryol 2018 ;59(3):699-702

Discipline of Pharmacology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania;

Diabetes mellitus is the leading cause of non-traumatic amputations worldwide. Ulcer of the diabetic foot is one of the most prevalent lesions of diabetic patients and it occurs in the natural evolution of the disease as a tardive complication. Neuropathy is the main determinant of foot ulcer. Read More

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January 2018

Clinical, histological and therapeutic modern approach of Ledderhose disease.

Rom J Morphol Embryol 2018 ;59(3):691-697

Department of Anesthesiology and Intensive Care, Emergency Clinical Hospital of Bucharest, Romania;

Ledderhose disease or plantar fibromatosis is a rare hyperproliferative disorder of the plantar aponeurosis, clinically characterized by nodules situated especially on the medial border of the foot. It is histopathologically associated with Dupuytren's disease. This disease has some risk factors, like old age, alcohol or nicotine abuse, liver dysfunction, trauma or exposure to vibrations and autoimmune disorders, but the exact etiology is still unknown. Read More

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January 2018

Extra-tunnel Compression Mimicking Tarsal Tunnel Syndrome: Ultrasound Imaging for a Plantar Ganglion Cyst.

Med Ultrason 2018 Dec;20(4):540-541

Department of Physical and Rehabilitation Medicine Hacettepe University Medical School, Ankara, Turkey.

We reported a 43-year-old man with right-foot numbness under the tentative diagnosis of tarsal tunnel syndrome. The initial ultrasound examination did not identify any remarkable findings at the level of the medial malleolus. Owing to the failure of conservative treatments, he was referred for US-guided injection of the tibial nerve. Read More

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December 2018

THE INFLUENCE OF SENSORIMOTOR TRAINING MODALITIES ON BALANCE, STRENGTH, JOINT FUNCTION, AND PLANTAR FOOT SENSITIVITY IN RECREATIONAL ATHLETES WITH A HISTORY OF ANKLE SPRAIN: A RANDOMIZED CONTROLLED PILOT STUDY.

Int J Sports Phys Ther 2018 Dec;13(6):993-1007

Niederrhein University of Applied Sciences, Faculty of Health Care, Therapeutic Sciences, Reinarzstr. 49, 47805 Krefeld, Germany.

Background: Ankle sprains frequently result in persistent sensorimotor deficits. Sufficient evidence of effects of sensorimotor training using unstable devices on physical functions is lacking. There is no insight as to whether simultaneous tactile stimulation of plantar foot mechanoreceptors using textured surfaces may influence outcomes in people with a history of ankle sprain. Read More

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December 2018

Combined Lag Screw and Cerclage Wire Fixation for Calcaneal Tuberosity Avulsion Fractures.

Case Rep Orthop 2018 11;2018:6207024. Epub 2018 Nov 11.

Klinik für Unfall und Wiederherstellungschirurgie, Universitätsklinikum Carl Gustav Carus, Dresden, Germany.

Avulsion fractures of the calcaneal tuberosity represent a rare injury pattern that is caused by a powerful tension force from the Achilles tendon and is usually seen following minor trauma, especially in elderly patients. The objective of this study is to describe a surgical technique using cerclage wiring through cannulated screws in the treatment of extra- and intra-articular avulsion fractures of the calcaneal tuberosity and to present our results in a small patient's cohort. Through a 5. Read More

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November 2018

Reinforcing kangaroo mother care uptake in resource limited settings.

Matern Health Neonatol Perinatol 2018 4;4:26. Epub 2018 Dec 4.

Pacific Medical College and Hospital, Udaipur, 313 001 India.

Background: The national and global coverage of kangaroo mother care (KMC) remains low. Hence, adjuncts to KMC may be necessary, especially on day1 of life when neonatal mortality is high. It is important to provide warmth and reduce mortality in preterm low birth weight (LBW) infants in the community/hospital setting. Read More

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December 2018

Delayed Diagnosis of Psoriatic Arthritis Mutilans due to Arthritis Prior to Skin Lesion.

Case Rep Rheumatol 2018 4;2018:4216938. Epub 2018 Nov 4.

Department of Orthopedic Surgery, Tokyo Women's Medical University, Tokyo, Japan.

Psoriatic arthritis (PsA) is a type of inflammatory arthritis characterized by cutaneous psoriasis, peripheral joint damage, axial joint damage, and enthesitis and is usually diagnosed after the appearance of psoriatic skin disease. PsA mutilans is relatively rare in Japan. In the present case, the patient was diagnosed with PsA with foot mutilans deformity only. Read More

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November 2018

The 18 kDa Translocator Protein (TSPO) Overexpression in Hippocampal Dentate Gyrus Elicits Anxiolytic-Like Effects in a Mouse Model of Post-traumatic Stress Disorder.

Front Pharmacol 2018 23;9:1364. Epub 2018 Nov 23.

State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing, China.

The translocator protein (18 kDa) (TSPO) recently attracted increasing attention in the pathogenesis of post-traumatic stress disorder (PTSD). This study is testing the hypothesis that the overexpression of TSPO in hippocampus dentate gyrus (DG) could alleviate the anxiogenic-like response in the mice model of PTSD induced by foot-shock. In this study, hippocampal DG overexpression of TSPO significantly reversed the increase of the contextual freezing response, the decrease of the percentage of both entries into and time spent in the open arms in elevated plus maze test and the decrease of the account of crossings from the dark to light compartments in light-dark transition test induced by electric foot-shocks procedure. Read More

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November 2018

The Ashtamudi Lake short-neck clam: re-assigned to the genus H. Adams & A. Adams, 1857 (Bivalvia, Veneridae).

Zookeys 2018 28(799):1-20. Epub 2018 Nov 28.

Department of Aquatic Biology and Fisheries, University of Kerala, Thiruvananthapuram- 695581, Kerala, India University of Kerala Kerala India.

The economically valuable bivalve mollusc, known as the short-neck clam, is the major fishery resource of the brackishwater Ashtamudi Lake in Kerala, India. This fishery carries a Marine Stewardship Council certification for sustainability wherein it and all hitherto published reports identify the short-neck clam or yellow-foot clam as (Dillwyn, 1817). It is noted that this name does not conform with current nomenclature and is now correctly referred to (Gmelin, 1791). Read More

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November 2018

Evaluation of Multi-Slice Spiral Computed Tomography in Simulation of Individualized Cervical Pedicle Screw Placement at C3-C7 in Chinese Healthy Population.

Indian J Orthop 2018 Nov-Dec;52(6):651-656

Imaging Center, Wuxi People's Hospital Affiliated to Nanjing Medical University, Jiangsu Province, China.

Background: Cervical pedicle screw fixation through posterior approach has shown greater cervical stability advantage. The cervical pedicle screw fixation technique through posterior approach is demanding. The key to the technique is the choice of point and angle of screw entrance. Read More

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December 2018

Interobserver Reliability of Pirani Clubfoot Severity Scoring between an Orthopedic Surgeon, a Resident Doctor, and a Nonmedical Counsellor at a Clubfoot Clinic.

Indian J Orthop 2018 Nov-Dec;52(6):645-650

Department of Orthopaedics, Gandhi Medical College, Bhopal, Madhya Pradesh, India.

Background: Ponseti method is the gold standard treatment for idiopathic congenital clubfoot. Pirani clubfoot severity score is a vital tool in assessing treatment of clubfoot. This study determines whether, after a short training in the Pirani scoring, a nonmedical personnel can be as accurate as a doctor in assessing the degree of deformity in clubfoot. Read More

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December 2018

Development of real-time reverse transcription recombinase polymerase amplification (RPA) for rapid detection of peste des petits ruminants virus in clinical samples and its comparison with real-time PCR test.

Sci Rep 2018 Dec 10;8(1):17760. Epub 2018 Dec 10.

OIE Reference Laboratory for Peste des Petits Ruminants, National Research Center for Exotic Animal Diseases, China Animal Health and Epidemiology Center, Qingdao, Shandong, P. R. China.

Peste des petits ruminants (PPR), caused by small ruminant morbillivirus (SRMV), formerly called peste des petits ruminants virus (PPRV), is one of the most important pathogens in small ruminants, and has tremendous negative economic impact on the sheep industry worldwide. Current detection of PPRV in clinical samples mainly relies on real-time RT-PCR. Particularly, samples collected from rural area require highly equipped laboratories for screening. Read More

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December 2018

Unexpected mode of engagement between enterovirus 71 and its receptor SCARB2.

Nat Microbiol 2018 Dec 10. Epub 2018 Dec 10.

Division of Structural Biology, The Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.

Enterovirus 71 (EV71) is a common cause of hand, foot and mouth disease-a disease endemic especially in the Asia-Pacific region. Scavenger receptor class B member 2 (SCARB2) is the major receptor of EV71, as well as several other enteroviruses responsible for hand, foot and mouth disease, and plays a key role in cell entry. The isolated structures of EV71 and SCARB2 are known, but how they interact to initiate infection is not. Read More

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December 2018

Exploration of potential risks of Hand, Foot, and Mouth Disease in Inner Mongolia Autonomous Region, China Using Geographically Weighted Regression Model.

Sci Rep 2018 Dec 7;8(1):17707. Epub 2018 Dec 7.

School of Sciences, Inner Mongolia University of Technology, Department of Mathematics, Hohhot, 010051, China.

To quantify the associations between the spatial characteristics of hand, foot, and mouth disease (HFMD) epidemic and meteorological factors (average temperature (AT), relative humidity (RH), average pressure (AP), average wind speed (AW) and average rainfall (AR)), child population density (CPD) and Per capita GDP (GDP) in Inner Mongolia Autonomous Region, China, and to detect the variation of influence in different seasons and counties, geographically weighted regression (GWR) model was constructed. The monthly cumulative incidence (CI) of HFMD was worked out for children ≤9 years from June to December, 2016. The results revealed that GWR model had a far superior goodness-of-fit for describing the relationship between the risk factors and HFMD incidence. Read More

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December 2018

Intralesional and perilesional application of an epidermal growth factor (Heberprot-P®) in diabetic foot ulcers. Part one.

Angiol Sosud Khir 2018 ;24(4):33-42

National Institute of Angiology and Vascular Surgery, Havana, Cuba.

For 15 years, from 2001, we began to apply Heberprot-P®, an injectable Epidermal Growth Factor (0.75 μg) created in the Center of Biotechnology, in Havana, Cuba. More than 159,000 patients were treated around the world, from 25 countries, with, with only 9-11% high-level amputations. Read More

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January 2018

[Cytophlavin inclusion in complex treatment of diabetic foot syndrome with signs of lower limb blood vessels medicalcinosis].

Khirurgiia (Mosk) 2018 (10):69-72

St. Petersburg Medical and Social Institute, St. Petersburg, Russia.

The aim of this study was to evaluate the effect of cytoflavin inclusion in therapy regimens of patients with diabetic foot syndrome and medicalcinosis on the microcirculation of the lower limb blood vessels. For this purpose, 64 patients with type II diabetes mellitus (subcompensated form), diabetic foot syndrome and signs of medicalcinosis foot blood vessels of various severity were examined. All patients were divided into 2 groups depending on the therapy scheme: patients of group I (33 people) received insulin, antibiotics, disaggregants, statins, anti-inflammatory drugs, painkillers, detoxification therapy. Read More

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January 2018

Integration of Wearable Sensors Into the Evaluation of Running Economy and Foot Mechanics in Elite Runners.

Curr Sports Med Rep 2018 Dec;17(12):480-488

Collaborating Centre of Sports Medicine, University of Brighton, Eastbourne, UNITED KINGDOM.

Running economy, known as the steady-state oxygen consumption at a given submaximal intensity, has been proposed as one of the key factors differentiating East African runners from other running communities around the world. Kenyan runners have dominated middle- and long-distance running events and this phenomenon has been attributed, in part at least, to their exceptional running economy. Despite such speculation, there are no data on running mechanics during real-life situations such as during training or competition. Read More

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December 2018
1 Read

5-Fluorouracil rechallenge after 5-fluorouracil-induced hyperammonemic encephalopathy.

Anticancer Drugs 2018 Dec 10. Epub 2018 Dec 10.

Medical Oncology Department, Gustave Roussy, Université Paris-Saclay.

For several decades, 5-Fluorouracil (5-FU) has been the backbone of many chemotherapy regimens for various tumor types. Its most common side effects are gastrointestinal disorders, mucositis, myelosuppression, hand-foot syndrome, and rarely cardiac toxicity. More rarely, 5-FU infusion can induce hyperammonemic encephalopathy. Read More

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December 2018

A painful, swelling and discharging sinus in the right foot.

Ann Saudi Med 2018 Nov-Dec;38(6):450

Dr. Nishant Nayyar, Department of Radiodiagnosis,, Indira Gandhi Medical College, Shimla, Himachal Pradesh 171001, India, T: 09418026199, nishant23rpgmc@ gmail.com, ORCID: http://orcid. org/0000-0003-2227-9105.

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December 2018

Comparison of walking quality variables between incomplete spinal cord injury patients and healthy subjects by using a footscan plantar pressure system.

Neural Regen Res 2019 Feb;14(2):354-360

Department of Orthopedics, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.

The main goal of spinal cord rehabilitation is to restore walking ability and improve walking quality after spinal cord injury (SCI). The spatiotemporal parameters of walking and the parameters of plantar pressure can be obtained using a plantar pressure analysis system. Previous studies have reported step asymmetry in patients with bilateral SCI. Read More

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February 2019
1 Read