143,489 results match your criteria Foot & ankle international / American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society[Journal]


Performance of stair negotiation in patients with cerebral palsy and stiff knee gait.

Gait Posture 2019 Apr 9;71:14-19. Epub 2019 Apr 9.

Clinic for Orthopedics and Trauma Surgery, Heidelberg University Hospital, Schlierbacher Landstrasse 200a, 69118 Heidelberg, Germany; Pediatric Orthopaedics and Traumatology, University, Children's Hospital Zurich - Eleonore Foundation, Steinwiesstrasse 75, 8032 Zurich, Switzerland. Electronic address:

Background: Due to the limited knee range of motion, achieving adequate foot clearance while walking on level ground constitutes a major problem for patients with cerebral palsy and stiff knee gait. Stair negotiation as an activity of daily life requires a considerably higher knee range of motion than level ground walking, but little is known yet as to whether such patients are able to walk stairs.

Research Question: The aim of this study was to investigate how patients with a limited knee range of motion negotiate stairs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09666362183178
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http://dx.doi.org/10.1016/j.gaitpost.2019.04.005DOI Listing
April 2019
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The effects of exercise and milk-fat globule membrane (MFGM) on walking parameters in community-dwelling elderly Japanese women with declines in walking ability: A randomized placebo controlled trial.

Arch Gerontol Geriatr 2019 Apr 5;83:106-113. Epub 2019 Apr 5.

Institute of Gerontology, J.F. Oberlin University, Tokyo, Japan.

Objective: To investigate the effects of exercise and milk fat globule membrane (MFGM) supplementation on walking ability and walking parameters in community-dwelling elderly Japanese women with declined walking ability.

Methods: A randomized placebo controlled trial was performed on 126 elderly community-dwelling women over 79 years old. Participants were randomly assigned to one of four three-month interventions: exercise and MFGM (Ex + MFGM), exercise and placebo (Ex + P), MFGM, and placebo interventions. Read More

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http://dx.doi.org/10.1016/j.archger.2019.03.029DOI Listing

The impact of topical phenytoin loaded nanostructured lipid carriers in diabetic foot ulceration.

Foot (Edinb) 2019 Mar 14;40:14-21. Epub 2019 Mar 14.

Department of Diabetes and Endocrinology, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt. Electronic address:

Objective: The aim of this study is to develop, and characterize nanostructured lipid carriers (NLCs) of phenytoin (PHT) in order to improve its entrapment efficiency and sustained release to improve the healing process.

Methods: Twenty-seven patients with neuropathic diabetic foot ulceration (DFU) were enrolled in this study. Patients were comparable regarding size, grading of ulcer and control of diabetes with no major deformity. Read More

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http://dx.doi.org/10.1016/j.foot.2019.03.007DOI Listing

Conditioned Pain Modulation Affects the Withdrawal Reflex Pattern to Nociceptive Stimulation in Humans.

Neuroscience 2019 Apr 15. Epub 2019 Apr 15.

Integrative Neuroscience, SMI®, Dept. of Health Science and Technology, Fredrik Bajers Vej 7, Aalborg, Ø, (9220, ), Aalborg, Denmark; Center for Neuroplasticity and Pain (CNAP), SMI®, Dept. of Health Science and Technology, Fredrik Bajers Vej 7, Aalborg, Ø, (9220, ), Aalborg, Denmark. Electronic address:

Human studies have repeatedly shown that conditioning pain modulation (CPM) exerts an overall descending inhibitory effect over spinal nociceptive activity. Previous studies have reported a reduction of the nociceptive withdrawal reflex (NWR) under CPM. Still, how descending control influences the muscle activation patterns involved in this protective behavior remains unknown. Read More

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http://dx.doi.org/10.1016/j.neuroscience.2019.04.016DOI Listing

Anhedonia following mild traumatic brain injury in rats: A behavioral economic analysis of positive and negative reinforcement.

Behav Brain Res 2019 Apr 15:111913. Epub 2019 Apr 15.

NeuroBehavioral Research Lab, Department of Veteran Affairs Medical Center, New Jersey Health Care System, East Orange, New Jersey, USA; Department of Pharmacology, Physiology and Neurosciences, New Jersey Medical School - Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA; Graduate School of Biomedical Sciences, New Jersey Medical School-Rutgers Biomedical and Health Sciences, Newark, New Jersey, USA. Electronic address:

Psychiatric disorders affect nearly 50% of individuals who have experienced a traumatic brain injury (TBI). Anhedonia is a major symptom of numerous psychiatric disorders and is a diagnostic criterion for depression. It has recently been appreciated that reinforcement may be separated into consummatory (hedonic), motivational and decisional components, all of which may be affected differently in disease. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01664328193034
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http://dx.doi.org/10.1016/j.bbr.2019.111913DOI Listing
April 2019
1 Read

Bioelectrical Impedance Analysis Does Not Detect an Increase in Total Body Water Following Isotonic Fluid Consumption.

Appl Physiol Nutr Metab 2019 Apr 18. Epub 2019 Apr 18.

Montclair State University, Exercise Science and Physical Education , 1 Normal Avenue , University Hall Suite 4136 , Montclair, New Jersey, United States , 07043 ;

Purpose: To determine if single frequency foot-to-foot bioelectrical impedance analysis (BIA) can detect acute changes in total body water (TBW) following consumption of isotonic saline.

Methods: All participants ate a sodium free meal 4hr prior to the data collection visit and had euhydration confirmed using urine specific gravity at the beginning of the experimental visit. Subjects drank 466mL of isotonic saline (Na+ 140mmol∙L-1) following baseline measures. Read More

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http://dx.doi.org/10.1139/apnm-2019-0106DOI Listing

Virtue Ethics in a Value-driven World: When Empathy Clouds Clinical Judgment.

Authors:
Casey Jo Humbyrd

Clin Orthop Relat Res 2019 May;477(5):952-954

C. J. Humbyrd, Assistant Professor of Orthopaedic Surgery and Chief, Foot and Ankle Division, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1097/CORR.0000000000000752DOI Listing

Difficulty differentiating a case of posterior cortical atrophy from a psychogenic disturbance of vision.

Authors:
Eiji Kirino

Psychogeriatrics 2019 Apr 17. Epub 2019 Apr 17.

Department of Psychiatry, Juntendo University School of Medicine, Tokyo, Japan.

Differentiating posterior cortical atrophy (PCA) from other diseases can be difficult and time-consuming, and there is a particularly high possibility of misdiagnosis when psychiatrists diagnose complaints related to visual perception. Here, a case of PCA involving prominent visual perceptual disorders is reported; PCA was difficult to distinguish from psychogenic disturbance of vision in this case. For a year, a 59-year-old woman had had visual perceptual disorders, including a distorted view and prosopagnosia. Read More

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http://dx.doi.org/10.1111/psyg.12455DOI Listing

OMERACT agreement and reliability study of ultrasonographic elementary lesions in osteoarthritis of the foot.

RMD Open 2019 8;5(1):e000795. Epub 2019 Mar 8.

Scienze Cliniche e Biologiche, Università degli Studi di Torino, Rome, Italy.

Objective: To evaluate the level of agreement on ultrasonographic (US) lesions among highly experienced sonographers as well as the intraobserver and interobserver reliability of inflammatory and structural US lesions in patients with osteoarthritis (OA) of the foot.

Methods: After a systematic literature review, a Delphi survey was performed to test definitions of US lesions in OA of the foot, including inflammatory lesions (ie, synovial hypertrophy [SH], joint effusion [JE], power Doppler signal [PD]), and structural abnormalities (ie, cartilage damage [CD] and osteophytes). Subsequently, the reliability of US in assessing the aforementioned lesions was tested on static images as well as during a live exercise. Read More

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http://dx.doi.org/10.1136/rmdopen-2018-000795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443136PMC

Empowering podiatrists to perform pulse checks for opportunistic atrial fibrillation detection during annual diabetes foot checks.

Open Heart 2019 6;6(1):e000795. Epub 2019 Feb 6.

Academic Health Science Network North East and North Cumbria (AHSN), Biomedical Research Building, Campus for Ageing and Vitality, Newcastle, UK.

Objective: To determine whether training podiatrists to provide opportunistic screening for atrial fibrillation (AF) during the local diabetes foot check was feasible and whether it detects previously unknown AF.

Method: During the initiative, 45 podiatrists from across North Durham, Darlington and Durham Dales Easington and Sedgefield Clinical Commissioning Groups were trained to recognise heart irregularities when taking pulse readings of feet of patients with diabetes during their annual foot screening reviews.

Results: Over the course of the 3-month pilot, 5000 patients with diabetes had their feet pulse-tested. Read More

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http://dx.doi.org/10.1136/openhrt-2018-000795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443127PMC
February 2019

Holocord syrinx presenting with foot drop.

J Surg Case Rep 2019 Apr 12;2019(4):rjz082. Epub 2019 Apr 12.

Neurosurgery, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK.

We present an unusual presentation of holocord syrinx. A 4-year-old boy presenting a 2-week history of right sided foot drop. An MRI revealed a holocord secondary to a chiari one malformation. Read More

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http://dx.doi.org/10.1093/jscr/rjz082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6460900PMC

Programming accelerated DNA walkers in diffusion-limited microenvironments.

Chem Sci 2019 Mar 22;10(10):3103-3109. Epub 2019 Jan 22.

Key Laboratory of Biomedical Information Engineering of Ministry of Education , School of Life Science and Technology , Xi'an Jiaotong University , Xianning West Road , Xi'an , Shaanxi 710049 , P. R. China . Email:

Macromolecule diffusion in cellular microenvironments dictates the kinetics of biochemical processes, yet inevitably limiting the assembly and operation of biomimetic motors. Herein we program accelerated DNA walkers in diffusion-limited microenvironments such as molecularly crowded solutions and cytoplasm. All DNA components, including single-foot walkers, chemically damaged tracks and calibration elements, are anchored on individual gold nanoparticles. Read More

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http://dx.doi.org/10.1039/c8sc05302bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432271PMC

First presentation of a Nora-lesion of the talus in a paraossal fasciitis.

Orthop Rev (Pavia) 2019 Feb 27;11(1):7628. Epub 2019 Mar 27.

Department of Orthopedics and Orthopedic Rheumatology, Elisabeth- Klinik, Olsberg.

Nora-Lesion is a proliferation that normally develops out of an intact corticalis. The entity of this fibroostotic pseudotumor, as discussed in literature, is triggered from repeating trauma or reactive periosteitis. In the literature, there are more than 200 cases defined as Nora lesion. Read More

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http://dx.doi.org/10.4081/or.2019.7628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452091PMC
February 2019

Comparison of gait with and without ankle-foot orthoses after lower limb surgery in children with unilateral cerebral palsy.

J Child Orthop 2019 Apr;13(2):180-189

Medical Faculty, Department of Interdisciplinary Health Science, University of Oslo, Oslo, Norway.

Purpose: Children with spastic unilateral cerebral palsy (SUCP) frequently undergo lower limb surgery to improve gait. Postoperatively, ankle-foot orthoses (AFOs) are used to maintain the surgical corrections and provide adequate mechanical support. Our aim was to evaluate changes in gait and impacts of AFOs one-year postoperatively. Read More

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http://dx.doi.org/10.1302/1863-2548.13.180146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442508PMC

Understanding the foot's functional anatomy in physiological and pathological conditions: the calcaneopedal unit concept.

J Child Orthop 2019 Apr;13(2):134-146

Orthopedic Surgery Department, Hôpital Necker-Enfants Malades, University of Paris Descartes, Paris, France.

Background: A thorough review of the available orthopaedic literature shows significant controversies, inconsistencies and sparse data regarding the terminology used to describe foot deformities. This lack of consensus on terminology creates confusion in professional discussions of foot anatomy, pathoanatomy and treatment of deformities. The controversies apply to joint movements as well as static relationships between the bones. Read More

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http://dx.doi.org/10.1302/1863-2548.13.180022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442506PMC
April 2019
1 Read

[Spinal cord stimulation for non-reconstructable chronic ritical limb ischemiae: a case report].

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Apr;51(2):362-364

Department of Vascular Surgery, Peking University People's Hospital, Beijing 100044, China.

Peripheral arterial disease is one part of systematic atherosclerosis, becoming a heavy burden of human health. Patients in end stage of peripheral arterial disease manifest critical limb ischemia with severe rest pain and refractory ulcer. Surgical revascularization is the optimal option for patients with critical limb ischemia to avoid major amputation and improve quality of life. Read More

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Enhanced discriminative aversive learning and amygdala responsivity in 5-HT transporter mutant mice.

Transl Psychiatry 2019 Apr 17;9(1):139. Epub 2019 Apr 17.

Department of Experimental Psychology, University of Oxford, Oxford, UK.

Genetic variation in the human serotonin transporter (5-HTT) has been linked to altered fear learning but the data are inconsistent and the mechanism is unclear. The present study investigated conditioned aversive learning in 5-HTT knockout (KO) mice while simultaneously recording neural network activity (theta oscillations) and hemodynamic responses (tissue oxygen delivery) from the amygdala, a brain region necessary for forming fearful memories. Conditioned aversive learning was measured using a discrimination learning task in which one auditory cue was paired with foot-shock, whereas a second auditory cue was not. Read More

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http://dx.doi.org/10.1038/s41398-019-0476-8DOI Listing

Cellular DNAJA3, a Novel VP1-Interacting Protein, Inhibits Foot-and-Mouth Disease Virus Replication by Inducing Lysosomal degradation of VP1 and Attenuating its Antagonistic Role on the IFN-β signaling pathway.

J Virol 2019 Apr 17. Epub 2019 Apr 17.

State Key Laboratory of Veterinary Etiological Biology, National Foot and Mouth Diseases Reference Laboratory, Key Laboratory of Animal Virology of Ministry of Agriculture, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, Gansu, China

DnaJ Heat Shock Protein Family (Hsp40) Member A3 (DNAJA3) plays an important role in viral infections. However, the role of DNAJA3 in replication of foot-and-mouth-disease virus (FMDV) remains unknown. In this study, DNAJA3, a novel binding partner of VP1, was identified using yeast two-hybrid screening. Read More

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http://dx.doi.org/10.1128/JVI.00588-19DOI Listing

Enterovirus A71 Containing Codon-Deoptimized VP1 and High-Fidelity Polymerase as Next Generation Vaccine Candidate.

J Virol 2019 Apr 17. Epub 2019 Apr 17.

Department of Medical Laboratory Science and Biotechnology, College of Medicine, National Cheng Kung University, Tainan, Taiwan

Enterovirus A71 (EV-A71) is the major pathogen which causes hand-foot-and-mouth disease (HFMD) which occasionally results in severe neurological complications. In this study, we developed four EV-A71 (rgEV-A71) strains by reverse genetics procedures as possible vaccine candidates. The four rgEV-A71 viruses contained various codon deoptimized VP1 capsid protein (VP1-CD) showed similar replication rate and antigenicity to wild-type virus, while a fifth virus, rg4643C4VP-CD, was unable to form plaques, but was still able to examined by TCID50 titers which were similar to the others, thus indicating the effect of CD on plaque formation. Read More

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http://dx.doi.org/10.1128/JVI.02308-18DOI Listing

EP1 receptor is involved in prostaglandin E2-induced osteosarcoma growth.

Bosn J Basic Med Sci 2019 Apr 18. Epub 2019 Apr 18.

Department of Hand and Foot Surgery, The Second Hospital Affiliated to Soochow University, Suzhou; Department of Orthopedics, The Second Affiliated Hospital of Anhui Medical University, Hefei Anhui, China.

Recent studies showed that the activation of prostaglandin (PG) receptor EP1 promotes cell migration and invasion in different cancers. The aim of this study was to investigate the role of EP1 in the proliferation of osteosarcoma (OS) cells in vitro and in vivo. EP1 mRNA and protein levels were analyzed by real-time RT-PCR and Western blot, respectively in human OS cell lines MG63, OS732, U-2OS, HOS and SAOS-2 compared to human fetal osteoblastic hFOB 1. Read More

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http://dx.doi.org/10.17305/bjbms.2019.4177DOI Listing

LiDAR-Based Real-Time Detection and Modeling of Power Lines for Unmanned Aerial Vehicles.

Sensors (Basel) 2019 Apr 16;19(8). Epub 2019 Apr 16.

INESC Technology and Science, Centre for Robotics and Autonomous Systems, 4200-465 Porto, Portugal.

The effective monitoring and maintenance of power lines are becoming increasingly important due to a global growing dependence on electricity. The costs and risks associated with the traditional foot patrol and helicopter-based inspections can be reduced by using UAVs with the appropriate sensors. However, this implies developing algorithms to make the power line inspection process reliable and autonomous. Read More

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http://dx.doi.org/10.3390/s19081812DOI Listing

Color-Changing Indicator to Monitor the Time-Temperature History during Cooking of Meats.

J Food Prot 1988 Jul;51(7):542-546

Frigorífico Rioplatense S. A., Ruta 9, Km. 32-1/2, Gral. Pacheco, Pcia. de Buenos Aires, Argentina.

Development of a time-temperature integrator based on color changes produced by the chemical reaction between reducing sugars (i.e. fructose, glucose, lactose) and 1-lysine (Maillard's reaction), is described. Read More

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http://dx.doi.org/10.4315/0362-028X-51.7.542DOI Listing

[Hematoma of thight as popliteal block complication].

Agri 2019 Apr;31(2):101-103

Department of Anesthesia and Reanimation, Kocaeli University Faculty of Medicine, Kocaeli, Turkey.

This report was submitted to share an experience of the development of a local hematoma as a complication following ultrasound-guided popliteal block performance in a 92-year-old, American Society of Anaesthesiologists class III, male patient undergoing surgical excision of a malignant melanoma lesion in the base of the left foot performed by the plastic surgery department. Read More

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http://dx.doi.org/10.5505/agri.2017.35693DOI Listing

The long-term effects of an implantable drop foot stimulator on gait in hemiparetic patients.

PLoS One 2019 17;14(4):e0214991. Epub 2019 Apr 17.

Christian Doppler Laboratory for Restoration of Extremity Function, Medical University of Vienna, Vienna, Austria.

Drop foot is a frequent abnormality in gait after central nervous system lesions. Different treatment strategies are available to functionally restore dorsal extension during swing phase in gait. Orthoses as well as surface and implantable devices for electrical stimulation of the peroneal nerve may be used in patients who do not regain good dorsal extension. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214991PLOS
April 2019
7 Reads

Monoclonal antibodies point to Achilles' heel in picornavirus capsid.

Authors:
Mihnea Bostina

PLoS Biol 2019 Apr 17;17(4):e3000232. Epub 2019 Apr 17.

Department of Microbiology and Immunology and Otago Micro and Nano Imaging, University of Otago, Dunedin, New Zealand.

Picornaviruses are small, icosahedral, nonenveloped, positive-sense, single-stranded RNA viruses that form one of the largest and most important viral families. Numerous Picornaviridae members pose serious health or agricultural threats, causing diseases such as poliomyelitis, hepatitis A, or foot-and-mouth disease. The antigenic characterization of picornavirus capsids plays an important role in understanding the mechanism of viral neutralization and the conformational changes associated with genome release, and it can point to regions which can be targeted by small-molecule compounds to be developed as antiviral inhibitors. Read More

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http://dx.doi.org/10.1371/journal.pbio.3000232DOI Listing

Putative parapoxvirus-associated foot disease in the endangered huemul deer (Hippocamelus bisulcus) in Bernardo O'Higgins National Park, Chile.

PLoS One 2019 17;14(4):e0213667. Epub 2019 Apr 17.

One Health Institute, School of Veterinary Medicine, University of California, Davis, CA, United States of America.

The huemul (Hippocamelus bisulcus) is an endangered cervid endemic to southern Argentina and Chile. Here we report foot lesions in 24 huemul from Bernardo O'Higgins National Park, Chile, between 2005 and 2010. Affected deer displayed variably severe clinical signs, including lameness and soft tissue swelling of the limbs proximal to the hoof or in the interdigital space, ulceration of the swollen tissues, and some developed severe proliferative tissue changes that caused various types of abnormal wear, entrapment, and/or displacement of the hooves and/or dewclaws. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0213667PLOS

LIMPRINT in Australia.

Lymphat Res Biol 2019 Apr;17(2):173-177

7 School of Social Sciences, Nottingham University, Nottingham, United Kingdom.

Australia was one of nine participating countries in the epidemiology Phase II Lymphoedema Impact and Prevalence - International (LIMPRINT) project to determine the number of people with chronic edema (CO) in local health services. Data collection occurred through questionnaire-based interviews and clinical assessment with provided LIMPRINT tools. Four different types of services across three states in Australia participated. Read More

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http://dx.doi.org/10.1089/lrb.2018.0087DOI Listing

Subtar arthroscopic debridment for the treatment of sinus tarsi syndrome: case series.

Rev Assoc Med Bras (1992) 2019 Mar 11;65(3):370-374. Epub 2019 Apr 11.

Department of Orthopedics and Traumatology, Escola Paulista de Medicina, Federal University of São Paulo, SP, Brasil.

Objective: The objective of this study is to report the results of arthroscopic debridement of the subtalar joint in eight patients with Sinus Tarsi Syndrome (STS) refractory to conservative treatment.

Methods: This is a retrospective study of eight patients with STS who underwent subtalar arthroscopy for debridement of the sinus tarsi between January 2015 and January 2017 after six months of conservative treatment. All patients answered an epidemiological questionnaire and underwent functional evaluation with the Visual Analogue Pain Scale (VAS) and the American Orthopedic Foot and Ankle Society Score (AOFAS) in the preoperative and in the last evaluation (average of 12 months - 6-24 months). Read More

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http://dx.doi.org/10.1590/1806-9282.65.3.370DOI Listing

[Differentiated approach to treatment of decompensated lower limb ischaemia with the use of the WIFI classification system].

Angiol Sosud Khir 2019 ;25(1):9-16

Russian University of Friendship of Peoples, Moscow, Russia.

In the present article, the authors substantiate the necessity of subdividing a heterogeneous cohort of patients presenting with Fontaine-Pokrovsky grade IV critical limb ischaemia into subgroups with the aim of making an appropriate therapeutic decision and predicting the outcome. We also translated into the Russian language the WIfI classification system developed by the Society for Vascular Surgery (2014) in order to predict limb loss and feasibility of performing revascularization. This is followed by comments on the classification, accompanied by examples of own clinical case studies. Read More

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http://dx.doi.org/10.33529/angio2019101DOI Listing
January 2019
1 Read

New Persistent Opioid Use Following Common Forefoot Procedures for the Treatment of Hallux Valgus.

J Bone Joint Surg Am 2019 Apr;101(8):722-729

Departments of Orthopaedic Surgery (F.T.F, T.D.G., P.G.T., and J.R.H.), Surgery (H.M.H. and J.F.W.), and Anesthesiology (C.M.B.), University of Michigan, Ann Arbor, Michigan.

Background: Orthopaedic surgeons are the fourth highest on the list of top prescribers of opioid analgesics by specialty and have a direct impact on opioid-related morbidity in the United States. Operative bunion correction is one of the most commonly performed elective foot surgical procedures in this country. We sought to determine the rate of new persistent opioid use following exposure to opioids after surgical treatment of hallux valgus (bunionectomy) and to identify associated risk factors. Read More

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http://dx.doi.org/10.2106/JBJS.18.00793DOI Listing

Rigid Internal Fixation of Proximal Crescentic Metatarsal Osteotomy in Hallux Valgus Correction.

Foot Ankle Int 2019 Apr 17:1071100719842800. Epub 2019 Apr 17.

1 Saint Alphonsus Medical Group, Coughlin Foot & Ankle Clinic, Boise, ID, USA.

Background: The purpose of this study was to evaluate outcomes utilizing a low-profile titanium plate and screw construct for rigid fixation of first ray proximal crescentic osteotomies in the treatment of hallux valgus.

Methods: Forty-eight patients (53 feet) with mild to severe hallux valgus were prospectively enrolled and completed 12-month follow-up. All were treated with a proximal crescentic osteotomy, fixed with a low-profile titanium plate, distal soft tissue correction, with or without an Akin osteotomy. Read More

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http://dx.doi.org/10.1177/1071100719842800DOI Listing

Hand-foot-and-mouth-disease-induced Koebner phenomenon in psoriasis.

J Dtsch Dermatol Ges 2019 Apr 17. Epub 2019 Apr 17.

Department of Dermatology, Cathay General Hospital, Taipei, Taiwan.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/ddg.13824
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http://dx.doi.org/10.1111/ddg.13824DOI Listing
April 2019
1 Read

Relationships between differences in the number of fiber bundles of the anterior talofibular ligament and differences in the angle of the calcaneofibular ligament and their effects on ankle-braking function.

Surg Radiol Anat 2019 Apr 16. Epub 2019 Apr 16.

Department of Anatomy, School of Life Dentistry at Niigata, Nippon Dental University, Niigata, Japan.

Purpose: The aim was to clarify the relationships between differences in the number of fiber bundles of the anterior talofibular ligament (ATFL) and differences in the angle of the calcaneofibular ligament (CFL) with respect to the long axis of the fibula and their effects on ankle braking function.

Methods: The study sample included 110 Japanese cadavers. ATFLs were categorized as: Type I with one fiber bundle; Type II with two fiber bundles with incomplete separation and complete separation; and Type III with three fiber bundles. Read More

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http://dx.doi.org/10.1007/s00276-019-02239-2DOI Listing

The social Simon effect in the tactile sensory modality: a negative finding.

Cogn Process 2019 Apr 16. Epub 2019 Apr 16.

Institut des Systèmes Intelligents et de Robotique (ISIR), Sorbonne Université, CNRS, 4 place Jussieu, 75252, Paris CEDEX 05, France.

This study seeks to investigate whether users activate cognitive representations of their partner's action when they are involved in tactile collaborative tasks. The social Simon effect is a spatial stimulus-response interference induced by the mere presence of a partner in a go/nogo task. It has been extensively studied in the visual and auditory sensory modalities, but never before in the tactile modality. Read More

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http://dx.doi.org/10.1007/s10339-019-00911-4DOI Listing

Chronic lower leg pain: entrapment of common peroneal nerve or tibial nerve.

Unfallchirurg 2019 Apr 16. Epub 2019 Apr 16.

Departments of Surgery, Neurology and Sports Medicine, Maxima Medical Center, De Run 4600, 7777, 5500 MB, Veldhoven, The Netherlands.

Young individuals with chronic exercise-induced lower leg pain (ELP) who have normal compartmental muscle pressures and normal imaging occasionally suffer from a nerve entrapment syndrome. These patients have consistently undergone a variety of diagnostic tests and often futile therapies prior to arriving at the correct diagnosis. Awareness among traumatologists regarding these nerve entities is low. Read More

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http://link.springer.com/10.1007/s00113-019-0645-5
Publisher Site
http://dx.doi.org/10.1007/s00113-019-0645-5DOI Listing
April 2019
1 Read

Endovascular Repair of an Iliac Artery Pseudoaneurysm Using a Surgeon-Reconstructed Prosthetic Graft and a Bare Metal Stent.

Vasc Specialist Int 2019 Mar;35(1):34-38

Department of Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.

Iliac artery aneurysms are usually asymptomatic. Herein, we report a novel strategy for the repair of a pseudoaneurysm involving the external iliac artery using a conventional artificial graft and bare metal stent. A 76-year-old male patient presented with severe resting pain and right foot discoloration. Read More

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http://dx.doi.org/10.5758/vsi.2019.35.1.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453594PMC

Vaccine usage in western Canadian cow-calf herds.

Can Vet J 2019 Apr;60(4):414-422

Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4.

The aims of this study were to describe when and how vaccines are administered during the production cycle in cow-calf herds in western Canada, as well as the factors that influence vaccine usage as reported by producers. The most commonly used vaccines were bovine viral diarrhea virus/infectious bovine rhinotracheitis (BVDV/IBR) in adult animals and clostridial vaccines in calves. While there has been improvement in usage of reproductive and respiratory viral vaccines since previous studies, there are still several areas in which uptake could be improved. Read More

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April 2019
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High-frequency dynamics of evanescently-coupled nanowire lasers.

Sci Rep 2019 Apr 16;9(1):6126. Epub 2019 Apr 16.

Institute of Photonics, SUPA Department of Physics, University of Strathclyde, TIC Centre, 99 George Street, Glasgow, G1 1RD, UK.

We analyse the dynamics and conditions for stability in an array of two laterally-coupled nanowire lasers in terms of their separation, difference in resonant frequencies and pumping rate under conditions of weak coupling. We find that the regions of stability are very small and are found close to zero frequency offset between the lasers. Outside these regions various forms of instability including periodic oscillation, chaos and complex dynamics are predicted. Read More

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http://dx.doi.org/10.1038/s41598-019-42526-xDOI Listing

Surgical outcomes for chronic exertional compartment syndrome following improved diagnostic criteria.

J R Army Med Corps 2019 Apr 16. Epub 2019 Apr 16.

Academic Department of Military Rehabilitation, Defence Medical Rehabilitation Centre Headley Court, Epsom, UK.

Introduction: Chronic exertional compartment syndrome (CECS) presents with pain during exercise, most commonly within the anterior compartment of the lower limb. A diagnosis is classically made from a typical history and the measurement of intramuscular compartmental pressure (IMCP) testing. Improved, more specific diagnostic criteria for IMCP testing allow clinicians to now be more certain of a diagnosis of CECS. Read More

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http://dx.doi.org/10.1136/jramc-2019-001171DOI Listing

Accuracy of cone-beam computed tomography for syndesmosis injury diagnosis compared to conventional computed tomography.

Foot Ankle Surg 2019 Apr 1. Epub 2019 Apr 1.

Division of Radiology, Department of Imaging and Medical Informatics, Geneva University Hospitals, University of Geneva, Rue Gabrielle-Perret-Gentil 4, 1211 Geneva 14, Switzerland. Electronic address:

Background: Syndesmosis injury can lead to ankle mortise instability and early osteoarthritis. Several multiple detector computed tomography (MDCT) methods for measurement have been developed. Weight-bearing cone beam CT (WB CBCT) is an emerging technique that offers the possibility of upright-position scanning and lower doses. Read More

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http://dx.doi.org/10.1016/j.fas.2019.03.006DOI Listing

Varus talar tilt combined with an internal rotation pivot stress assesses the supination instability vector in lateral ankle ligaments' injury - cadaver study.

Foot Ankle Surg 2019 Mar 27. Epub 2019 Mar 27.

Department of Anatomy and Human Embryology, Faculty of Medicine, University of Barcelona, Spain; Department of Orthopaedics, Clinica del Remei, Barcelona, Spain.

Background: The lack of consensus on the relevance of the varus talar tilt test (VTTT) might be due to the divergence between the insufficiency vector of lateral ankle instability and the direction of this clinical test. Our hypothesis is that the VTTT is more accurate to diagnose lateral ankle ligaments rupture when it's applied with a pre-positioning of the foot in internal rotation (IR).

Methods: We compared, in 12 cadaver ankles, the varus opening during a classic VTTT with the same test starting in an IR pivot, using a new arthrometer. Read More

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http://dx.doi.org/10.1016/j.fas.2019.03.007DOI Listing

Establishing a common instantaneous center of rotation for the metatarso-phalangeal and metatarso-sesamoid joints: a theoretical geometric model based on specific morphometrics.

J Orthop Surg Res 2019 Apr 16;14(1):107. Epub 2019 Apr 16.

Center for Statistical Research and Methodology, U.S. Census Bureau, Washington, D.C., USA.

Background: Previous research has identified separate sagittal plane instantaneous centers of rotation for the metatarso-phalangeal and metatarso-sesamoid joints, but surprisingly, it does not appear that any have integrated the distinctive morphological characteristics of all three joints and their respective axes into a model that collectively unifies their functional motions. Since all joint motion is defined by its centers of rotation, establishing this in a complicated multi-dimensional structure such as the metatarso-phalangeal-sesamoid joint complex is fundamental to understanding its functionality and subsequent structural failures such as hallux abducto valgus and hallux rigidus.

Methods: Based on a hypothesis that it is possible to develop an instantaneous center of rotation common to all four osseous structures, specific morphometrics were selected from a sequential series of 0. Read More

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http://dx.doi.org/10.1186/s13018-019-1110-4DOI Listing

Risk of hand-foot skin reaction associated with VEGFR-TKIs: a meta-analysis of 57 randomized controlled trials involving 24956 patients.

J Am Acad Dermatol 2019 Apr 13. Epub 2019 Apr 13.

Department of Respiratory Medicine, Children's Hospital of Chongqing Medical University, Chongqing 400014, China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Pediatrics, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing 400014, China.

Background: Multiple randomized controlled trials have assessed hand-foot skin reaction (HFSR) caused by vascular endothelial growth factor receptor-tyrosine kinase inhibitors (VEGFR-TKIs).

Objective: We performed a meta-analysis in order to determine the incidence and the relative risk (RR) of HFSR associated with these agents.

Methods: Databases were searched for relevant studies. Read More

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http://dx.doi.org/10.1016/j.jaad.2019.04.021DOI Listing

Effects of Aerobic Exercise on Vibration Perception Threshold in Type 2 Diabetic Peripheral Neuropathy Population Using 3-sites Method: Single-blind Randomized Controlled Trial.

Altern Ther Health Med 2019 Mar;25(2):36-41

Objectivest: The purpose of this study was to examine the effects of 8 wk of moderate intensity aerobic exercise on vibration perception threshold (VPT) in type 2 diabetic peripheral neuropathy (DPN).

Methods: Single blind parallel group randomized controlled trial was done in a tertiary center. Stratified block randomization was used for selecting participants. Read More

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March 2019
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Extended Extracorporeal Shockwave Therapy for Chronic Diabetic Foot Ulcers: A Case Series.

Wounds 2019 Mar 15. Epub 2019 Mar 15.

Division of Plastic Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan; and Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.

Introduction: It is hypothesized that cumulative extended application of extracorporeal shockwave therapy (ESWT) can be beneficial to sustain the effect of ESWT and improve the long-term outcome in chronic diabetic foot ulcers (DFUs).

Objective: The purpose of this study is to investigate the effectiveness of multiple extended booster ESWT to maintain the effects of ESWT on the outcomes of chronic DFUs.

Materials And Methods: Four patients with a DFU were treated with ESWT, including 1 patient with 12 treatments and 3 patients with 6 treatments. Read More

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Assessing the Need for Mobile Health (mHealth) in Monitoring the Diabetic Lower Extremity.

JMIR Mhealth Uhealth 2019 Apr 16;7(4):e11879. Epub 2019 Apr 16.

Division of Plastic and Reconstructive Surgery, University of Toronto, Toronto, ON, Canada.

Background: Complications of the diabetic lower extremity (such as diabetic foot ulcers, DFUs) occur when monitoring is infrequent, and often result in serious sequelae like amputation or even death.

Objective: To evaluate the potential application of mobile health (mHealth) to diabetic foot monitoring. We surveyed the self-management routines of a group of diabetic patients, as well as patient and clinician opinions on the use of mHealth in this context. Read More

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https://mhealth.jmir.org/2019/4/e11879/
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http://dx.doi.org/10.2196/11879DOI Listing
April 2019
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Identification of novel epitopes in serotype O foot-and-mouth disease virus by in vitro immune selection.

J Gen Virol 2019 Apr 16. Epub 2019 Apr 16.

The Pirbright Institute, Ash Road, Woking, Surrey, GU24 0NF, UK.

Foot-and-mouth disease virus (FMDV) displays various epitopes on the capsid outer surface. In addition to the five neutralizing antigenic sites, there is evidence of the existence of other, yet unidentified, epitopes that are believed to play a role in antibody-mediated protection. Previous attempts to identify these epitopes revealed two additional substitutions at positions VP2-74 and -191 (5M2/5 virus) to be of antigenic significance. Read More

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http://dx.doi.org/10.1099/jgv.0.001259DOI Listing

Return to Sports and Physical Activities After First Metatarsophalangeal Joint Arthrodesis in Young Patients.

Foot Ankle Int 2019 Apr 16:1071100719842799. Epub 2019 Apr 16.

1 Department of Foot and Ankle Surgery, Hospital for Special Surgery, New York, NY, USA.

Background: Arthrodesis of the first metatarsophalangeal (MTP) joint has been shown to be effective in alleviating pain and correcting deformity in hallux rigidus. However, outcomes in specific sports and physical activities remain unclear. The aim of this study was to assess sports and physical activities in young patients following first MTP joint arthrodesis and to compare these results with clinical outcomes. Read More

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http://dx.doi.org/10.1177/1071100719842799DOI Listing

Effect of natural full weight-bearing during standing on the rotation of the first metatarsal bone.

Clin Anat 2019 Apr 16. Epub 2019 Apr 16.

Department of Radiology, Keio University, Tokyo, Japan.

Purpose: To evaluate the rotational change in the first metatarsal bone (1MT) of the foot during natural standing using an upright computed tomography (CT) scanner with 320-detector rows.

Material And Methods: A total of 52 feet of 28 asymptomatic subjects (aged 23-39 years) were evaluated in the natural standing position with or without weight-bearing. A foot pressure plate was used to determine the non-weight-bearing (NWB) or single leg full-weight-bearing (s-FWB) conditions. Read More

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http://dx.doi.org/10.1002/ca.23385DOI Listing

Controlled-release neurotensin-loaded silk fibroin dressings improve wound healing in diabetic rat model.

Bioact Mater 2019 Dec 28;4:151-159. Epub 2019 Mar 28.

Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, Guangdong Provincial Engineering and Technological Research Center for Drug Carrier Development, Department of Biomedical Engineering, Jinan University, Guangzhou, 510632, China.

Diabetic foot ulcers (DFU), which may lead to lower extremity amputation, is one of the severe and chronic complications of diabetic mellitus. This study aims to develop, and use dressings based on Silk fibroin (SF) as the scaffold material, gelatin microspheres (GMs) as the carrier for the neurotensin (NT), a neuropeptide that acts as an inflammatory modulator in wound healing and NT as accelerate wound healing drug to treat DFU. We evaluated the wound healing processes and neo-tissue formation in rat diabetic model by macroscopic observation, histological observation (H&E staining and Masson's trichrome staining) and immunofluorescence analysis at 3, 7, 14, 21 and 28 post-operation days. Read More

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http://dx.doi.org/10.1016/j.bioactmat.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447858PMC
December 2019