24,224 results match your criteria Food Allergies


Food allergen knowledge, attitude and practices among UK consumers: A structural modelling approach.

Authors:
Jan Mei Soon

Food Res Int 2019 Jun 9;120:375-381. Epub 2019 Mar 9.

Faculty of Health and Wellbeing, University of Central Lancashire, Preston PR1 2HE, UK. Electronic address:

Food allergies are becoming more prevalent and affect up to 1-2% of adults and 5-8% of children in the UK. This study investigated the food allergen knowledge, attitude towards food allergens and food allergy management practices among food allergic and intolerant consumers and/or their family members and carers. Questionnaires were distributed at three major Free From events in the UK in 2017 and 2018. Read More

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http://dx.doi.org/10.1016/j.foodres.2019.03.008DOI Listing

Detection of serum and salivary IgE and IgG1 immunoglobulins specific for diagnosis of food allergy.

PLoS One 2019 17;14(4):e0214745. Epub 2019 Apr 17.

Laboratory of Biotechnology and Molecular Biology, State University of Ceará, Fortaleza, Ceará, Brazil.

Given the growing incidence and prevalence of life-threatening food allergies, health concerns have raised new perspectives for in vivo and in vitro diagnostic methodologies, pointing to saliva as a promising material, already used to diagnose other pathologies. Based on the above considerations, this study aimed to verify the possible use of saliva for the detection of IgE and IgG1 in the diagnosis of food allergy. This was a randomized, cross-sectional clinical study with a quantitative approach, developed at a hospital referral center in allergy in the state of Ceará, from January to July 2015. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214745PLOS
April 2019
1 Read

Food Allergen Sensitisation Patterns in Omani Patients with Allergic Manifestations.

Sultan Qaboos Univ Med J 2018 Nov 28;18(4):e483-e488. Epub 2019 Mar 28.

Department of Microbiology, Sultan Qaboos University Hospital, Muscat, Oman.

Objectives: This study aimed to evaluate the relationship between food allergen sensitisation patterns and allergic manifestations in Omani patients and highlight the importance of specific immunoglobulin E (IgE) testing.

Methods: This retrospective study included all patients referred due to allergic manifestations to the Sultan Qaboos University Hospital (SQUH), Muscat, Oman, from November 2012 to November 2016. Specific IgE blood testing was performed to determine sensitisation to common foods known to cause allergic reactions. Read More

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https://journals.squ.edu.om/index.php/squmj/article/view/299
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http://dx.doi.org/10.18295/squmj.2018.18.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443266PMC
November 2018
2 Reads

Compartmentalized gut lymph node drainage dictates adaptive immune responses.

Nature 2019 Apr 15. Epub 2019 Apr 15.

Laboratory of Mucosal Immunology, The Rockefeller University, New York, NY, USA.

The intestinal immune system has the challenging task of tolerating foreign nutrients and the commensal microbiome, while excluding or eliminating ingested pathogens. Failure of this balance leads to conditions such as inflammatory bowel diseases, food allergies and invasive gastrointestinal infections. Multiple immune mechanisms are therefore in place to maintain tissue integrity, including balanced generation of effector T (T) cells and FOXP3 regulatory T (pT) cells, which mediate resistance to pathogens and regulate excessive immune activation, respectively. Read More

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http://www.nature.com/articles/s41586-019-1125-3
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http://dx.doi.org/10.1038/s41586-019-1125-3DOI Listing
April 2019
3 Reads

Greetings from foodland: Teaching biochemistry to BS students in food-related courses in Italy.

Biochem Mol Biol Educ 2019 Apr 15. Epub 2019 Apr 15.

Department of Food, Environmental, and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.

Biochemistry has always been a mandatory topic within BS courses aimed at food science students at the University of Milan, namely: Food Science & Technology and Catering Sciences. Addressing biochemistry topics in this peculiar setting requires: (i) specific focus on topics that are seldom considered in courses offered in bio-medical curricula; (ii) close integration with other area disciplines, such as food biotechnology; (iii) ad hoc design of laboratory classes; and (iv) an array of elective courses covering specific aspects of biochemistry. In this context, for example, protein chemistry is presented by using food proteins of known structure and discussed in terms of structural features in the raw materials and of structural and chemical modifications occurring upon processing. Read More

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http://dx.doi.org/10.1002/bmb.21245DOI Listing
April 2019
1 Read

IgE sensitization in a cohort of adolescents in southern Sweden and its relation to allergic symptoms.

Clin Mol Allergy 2019 2;17. Epub 2019 Apr 2.

Department of Respiratory Medicine and Allergology, Skåne University Hospital, Lund University, Lund, Sweden.

Background: There is a strong and consistent association between IgE sensitization and allergy, wheeze, eczema and food hypersensitivity. These conditions are also found in non-sensitized humans, and sensitization is found among individuals without allergy-related diseases. The aim of this study was to analyse the sensitization profile in a representative sample of the population, and to relate patterns of allergens and allergen components to allergic symptoms. Read More

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http://dx.doi.org/10.1186/s12948-019-0110-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444864PMC
April 2019
1 Read

Infant milk-feeding practices and food allergies, allergic rhinitis, atopic dermatitis, and asthma throughout the life span: a systematic review.

Am J Clin Nutr 2019 Mar;109(Supplement_7):772S-799S

USDA, Food and Nutrition Service, Alexandria, VA.

Background: During the Pregnancy and Birth to 24 Months Project, the USDA and Department of Health and Human Services initiated a review of evidence on diet and health in these populations.

Objectives: The aim of these systematic reviews was to examine the relation of 1) never versus ever feeding human milk, 2) shorter versus longer durations of any human milk feeding, 3) shorter versus longer durations of exclusive human milk feeding prior to infant formula introduction, 4) feeding a lower versus higher intensity of human milk to mixed-fed infants, and 5) feeding a higher intensity of human milk by bottle versus breast with food allergies, allergic rhinitis, atopic dermatitis, and asthma.

Methods: The Nutrition Evidence Systematic Review team conducted systematic reviews with external experts. Read More

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http://dx.doi.org/10.1093/ajcn/nqy283DOI Listing
March 2019
1 Read
6.770 Impact Factor

Oral Food Challenge in Food Protein-Induced Enterocolitis Syndrome by Fish: Is There Any Room for Improvement?

Int Arch Allergy Immunol 2019 Apr 12:1-7. Epub 2019 Apr 12.

Paediatric Allergy Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Background: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated gastrointestinal food hypersensitivity usually due to cow's milk or soy. Among the solid foods, rice is one of the most causative foods worldwide, but it varies depending on the geographic area. In the Mediterranean countries, fish is one of the most important triggers of FPIES. Read More

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http://dx.doi.org/10.1159/000497486DOI Listing
April 2019
1 Read

Specific Immunoglobulin G4 and Immunoglobulin E Titers to Common Food Antigens in Sera of Children With Allergic Rhinitis.

Altern Ther Health Med 2018 Nov;24(6):38-45

Context: Allergic rhinitis is a chronic disease that usually affects children. Its etiology has been investigated for years.

Objective: The aim of the study was to evaluate the diagnostic value of immunoglobulin G4 (IgG4) against common food allergens, to determine the correlation between it and immunoglobulin E (IgE), and to evaluate the role of IgG4 (ie, whether its presence should be considered to be a significant factor that induces hypersensitivity or whether an effector role in allergic rhinitis could be attributed to it). Read More

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November 2018
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Prevalence of food hypersensitivity in relation to IgE sensitisation to common food allergens among the general adult population in West Sweden.

Clin Transl Allergy 2019 1;9:22. Epub 2019 Apr 1.

2Department of Internal Medicine and Clinical Nutrition, Krefting Research Centre, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Background: The prevalence of self-experienced adverse reactions to foods seems to have an increasing trend in both adults and children. However, it is unclear if the prevalence of food hypersensitivity in the Swedish adult population is still rising, what symptoms are caused by different foods and which are the most common foods to which adults are more frequently IgE-sensitised.

Methods: In a cross-sectional study based on questionnaire responses, interviews and clinical examinations as part of the West Sweden Asthma Study, 1042 subjects from the general population, 17-78 years of age, living in Västra Götaland, Sweden, were included. Read More

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https://ctajournal.biomedcentral.com/articles/10.1186/s13601
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http://dx.doi.org/10.1186/s13601-019-0261-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442429PMC
April 2019
2 Reads

Prevalence of food allergy among schoolchildren in Kuwait and its association with the coexistence and severity of asthma, rhinitis, and eczema: A cross-sectional study.

Authors:
Ali H Ziyab

World Allergy Organ J 2019 30;12(4):100024. Epub 2019 Mar 30.

Department of Community Medicine and Behavioral Sciences, Faculty of Medicine, Kuwait University, Safat, Kuwait.

Background: Food allergy (FA) is a common public health problem that affects both children and adults. Empirical knowledge of the burden of FA in Kuwait is limited. This study sought to estimate the prevalence of FA among schoolchildren in Kuwait and assess associations between FA and the coexistence and severity of asthma, rhinitis, and eczema. Read More

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http://dx.doi.org/10.1016/j.waojou.2019.100024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441753PMC
March 2019
1 Read

Molecular characterization of B-cell epitopes for the major fish allergen, parvalbumin, by shotgun proteomics, protein-based bioinformatics and IgE-reactive approaches.

J Proteomics 2019 Apr 8;200:123-133. Epub 2019 Apr 8.

Spanish National Research Council (CSIC), Marine Research Institute (IIM), Food Technology, Vigo, Pontevedra, Spain.

Parvalbumins beta (β-PRVBs) are the main fish allergens. The only proven and effective treatment for this type of hypersensitivity is to consume a diet free of fish. We present the molecular characterization of B-cell epitopes by shotgun proteomics of different β-PRVBs combined with protein-based bioinformatics and IgE-reactive approaches. Read More

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http://dx.doi.org/10.1016/j.jprot.2019.04.005DOI Listing
April 2019
4 Reads

Analysis of Oral Food Challenge Outcomes in IgE-mediated Food Allergies to Almond in a Large Cohort.

J Allergy Clin Immunol Pract 2019 Apr 8. Epub 2019 Apr 8.

Massachusetts General Hospital for Children, Food Allergy Center, Department of Pediatrics, Massachusetts General Hospital, Boston, MA.

Background: While almond-specific IgE-mediated food allergies have traditionally been equated with other tree nut allergies, outcomes of oral food challenges to almond and the utility of clinical testing to predict IgE-mediated almond hypersensitivity is not well known.

Objective: To describe almond oral challenge outcomes and assess the predictive value of clinical testing.

Methods: 603 almond challenges performed for 590 patients, aged 1 to 66 years, were analyzed from Massachusetts General Hospital allergy practices. Read More

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http://dx.doi.org/10.1016/j.jaip.2019.03.049DOI Listing
April 2019
2 Reads

Stopping when knowing: use of snus and nicotine during pregnancy in Scandinavia.

ERJ Open Res 2019 Apr 8;5(2). Epub 2019 Apr 8.

Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

In young women, the use of snus increases in parallel with decreasing smoking rates but the  use in pregnancy is unclear. Our aims were to determine the prevalence of snus use, smoking and other nicotine-containing product use during pregnancy, and to identify predictors for snus use in pregnancy. Prevalence was determined for 2528 women in Norway and Sweden based on the Preventing Atopic Dermatitis and ALLergies (PreventADALL) study, a population-based, mother-child birth cohort. Read More

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http://dx.doi.org/10.1183/23120541.00197-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452060PMC
April 2019
4 Reads

Parent-reported prevalence of food allergies in children with autism spectrum disorder: National health interview survey, 2011-2015.

Autism Res 2019 Apr 9. Epub 2019 Apr 9.

Department of Epidemiology and Biostatistics, Drexel University School of Public Health, Philadelphia, Pennsylvania.

Food allergies are frequently reported to co-occur with autism spectrum disorder (ASD), but the prevalence of this co-occurrence remains uncertain. In the present study, we examined parent-reported prevalence of co-occurring food allergy and ASD in a nationally representative sample of US children ages 2-17 in the National Health Interview Survey, study years 2011-2015. All analyses used survey weights to account for the complex sampling design. Read More

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http://dx.doi.org/10.1002/aur.2106DOI Listing
April 2019
1 Read

Conditioned "Cross Fading": The Incentive Motivational Effects of Mediated-Polysubstance Pairings on Alcohol, Marijuana, and Junk Food Craving.

J Health Commun 2019 Apr 9:1-9. Epub 2019 Apr 9.

b College of Journalism and Communications , University of Florida , Gainesville , FL , USA.

The bulk of mass media and substance cue research has examined the processes and effects of substance cue images in isolation under controlled experimental conditions. However, little attention has been devoted to delineating the specific outcomes associated with simultaneous polysubstance depictions. This study experimentally examined whether alcohol, marijuana, and junk food mediated cues influence craving independently and whether craving for these substances is co-facilitated by simultaneous polysubstance cue depictions. Read More

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http://dx.doi.org/10.1080/10810730.2019.1601304DOI Listing
April 2019
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Designer covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen.

Proc Natl Acad Sci U S A 2019 Apr 8. Epub 2019 Apr 8.

Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556;

Allergies are a result of allergen proteins cross-linking allergen-specific IgE (sIgE) on the surface of mast cells and basophils. The diversity and complexity of allergen epitopes, and high-affinity of the sIgE-allergen interaction have impaired the development of allergen-specific inhibitors of allergic responses. This study presents a design of food allergen-specific sIgE inhibitors named covalent heterobivalent inhibitors (cHBIs) that selectively form covalent bonds to only sIgEs, thereby permanently inhibiting them. Read More

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http://dx.doi.org/10.1073/pnas.1820417116DOI Listing
April 2019
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Identification of pyruvate kinase 2 as a possible crab allergen and analysis of allergenic proteins in crabs consumed in Taiwan.

Food Chem 2019 Aug 18;289:413-418. Epub 2019 Mar 18.

Department of Food Science, National Pingtung University of Science and Technology, Pingtung 912, Taiwan. Electronic address:

In Taiwan, crab is one of the main causes for food allergy. Several proteins are recognized as crustacean allergens, and tropomyosin is known to be the major one. However, sensitization patterns of Taiwanese patients to crustacean allergens remain unclear. Read More

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http://dx.doi.org/10.1016/j.foodchem.2019.03.074DOI Listing
August 2019
1 Read

Making Rash Decisions in Epilepsy: Evaluating Hypersensitivity Reactions to Anti-seizure Medications.

Epilepsy Curr 2019 Mar-Apr;19(2):96-98

The Frequency and Clinical Features of Hypersensitivity Reactions to Antiepileptic Drugs in Children: A Prospective Study Guvenir H, Dibek Misirlioglu E, Civelek E. J Allergy Clin Immunol Pract. 2018;6(6):2043-2050. Read More

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http://dx.doi.org/10.1177/1535759719835672DOI Listing
April 2019
1 Read

The Skin as an Immune Organ: Tolerance Versus Effector Responses, and Applications to Food Allergy and Hypersensitivity Reactions.

J Allergy Clin Immunol 2019 Apr 4. Epub 2019 Apr 4.

Laboratory for Investigative Dermatology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA.

Skin is replete with immune-competent cells that modulate signaling pathways to maintain a salubrious immunogenic/tolerogenic balance. This fertile immune environment plays a significant role in the development of allergic responses and sensitivities, but the mechanisms underlying these pathways have been underappreciated and underutilized with respect to developing therapeutics. Among the complex repertoire of cells that promote tolerogenic pathways in the periphery, two key classes include dendritic cells (DCs) and regulatory T cells (Tregs). Read More

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http://dx.doi.org/10.1016/j.jaci.2019.03.021DOI Listing
April 2019
1 Read

Esophageal IgE, IgG4, and mucosal eosinophilia in individuals with dysphagia.

Int Forum Allergy Rhinol 2019 Apr 5. Epub 2019 Apr 5.

Department of Otolaryngology-Head and Neck Surgery, Weill Cornell Medical College, New York, NY.

Background: Eosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus, producing failure to thrive in infants and dysphagia with food impaction in older children and adults. Although most people with EoE manifest atopic/allergic disease, the specific allergens to which immunoglobulin E (IgE) is directed, if any, have not yet been characterized.

Methods: Mucosal brush biopsy (MBB) and solid tissue biopsy (STB) specimens were prospectively obtained from 25 individuals with dysphagia and suspicion of EoE. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/alr.22339
Publisher Site
http://dx.doi.org/10.1002/alr.22339DOI Listing
April 2019
6 Reads

Fifteen-minute consultation: The EATERS method for the diagnosis of food allergies.

Arch Dis Child Educ Pract Ed 2019 Apr 4. Epub 2019 Apr 4.

The Adam Practice, Poole, UK.

The EATERS mnemonic is a novel method for taking an allergy focused clinical history. It provides a degree of certainty for diagnosing food allergy and can be used in both IgE and non IgE mediated reactions. EATERS will allow health care professionals to use their existing clinical skills to interpret the history of an allergic reaction, and by doing so will help to make sense of allergy test results. Read More

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http://dx.doi.org/10.1136/archdischild-2018-316397DOI Listing
April 2019
3 Reads

Food hypersensitivity-induced chronic gastrointestinal inflammation in a non-human primate model of diet-induced obesity.

PLoS One 2019 4;14(4):e0214621. Epub 2019 Apr 4.

Metabolism, Diabetes and Obesity Program, Biomedicine Discovery Institute, Monash University, Victoria, Australia.

Experimental non-human primate models of obesity are induced through the introduction of atypically calorically rich diets. Studies in captive-bred macaques show the development of obesity and diabetes with similar complications to humans including eye and kidney diseases, nerve damage associated with pain and blood vessel damage. Diets differ in outcomes and here we document inflammation of the gastrointestinal tract that can be exacerbated through these dietary interventions. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0214621PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448857PMC
April 2019
5 Reads

Gluten Analysis in Processed Foodstuffs by a Multi-Allergens and Grain-Specific UHPLC-MS/MS Method: One Method to Detect Them All.

J AOAC Int 2019 Apr 2. Epub 2019 Apr 2.

CER Groupe, Rue du point du Jour, 8, 6900 Marloie, Belgium.

Celiac disease, a complex, long-term autoimmune disorder and gluten intolerance, is estimated to affect from 1 to 5% of the world's population. As a consequence, to protect gluten-sensitive consumers, the development of reliable analytical methods allowing the detection of gluten in various food products is needed. Currently, ELISA is probably the most widespread used methodology. Read More

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http://dx.doi.org/10.5740/jaoacint.19-0057DOI Listing
April 2019
1 Read
1.385 Impact Factor

A Group Visit for High-Risk Pediatric Asthma Patients: A Quality Improvement Initiative to Improve Asthma Care.

Clin Pediatr (Phila) 2019 Apr 2:9922819839238. Epub 2019 Apr 2.

1 Boston Children's Hospital, Boston, MA, USA.

Introduction: Asthma disproportionately affects poor and minority children. Limited parental knowledge and confidence in asthma management, as well as stress from chronic illness, may contribute to poor outcomes. Novel approaches for providing care are essential for this vulnerable population. Read More

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http://dx.doi.org/10.1177/0009922819839238DOI Listing
April 2019
3 Reads

Gut microbial dysbiosis is associated with allergen-specific IgE responses in young children with airway allergies.

World Allergy Organ J 2019 25;12(3):100021. Epub 2019 Mar 25.

Division of Pediatric Pulmonology, Department of Pediatrics, Chang Gung Memorial Hospital at Linkou, Chang Gung University, Taoyuan, Taiwan.

Background: There is increasing evidence linking alterations of the gut microbial composition during early infancy to the development of atopic diseases and asthma. However, few studies have addressed the association of dysbiotic gut microbiota with allergic reactions through evaluation of feces in young children with allergic airway diseases.

Methods: We sought to evaluate relationships among gut microbiota, total fecal immunoglobulin E (IgE) levels, serum allergic sensitization, and their relevance to childhood allergic rhinitis and asthma. Read More

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http://dx.doi.org/10.1016/j.waojou.2019.100021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439417PMC

Different phenotypes and factors associated with atopic dermatitis in the young adult Singaporean Chinese population: A cross-sectional study.

World Allergy Organ J 2019 26;12(1):100008. Epub 2019 Jan 26.

Department of Biological Science, National University of Singapore, Singapore.

Background: Atopic dermatitis (AD) is a chronic allergic disease typically accompanied by atopy and thus, a tendency to develop allergic diseases such as allergic rhinitis, asthma or food allergies. Currently, individuals with AD are classified into those presenting with AD alone and those presenting with AD along with other allergic diseases (AD+). It is important to identify the various endophenotypes of AD using anthropometric, environmental, socio-economic, and disease history data in order to improve disease management. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S19394551193005
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http://dx.doi.org/10.1016/j.waojou.2018.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439406PMC
January 2019
7 Reads

"What do allergists in practice need to know about non-IgE-mediated food allergies".

Ann Allergy Asthma Immunol 2019 Mar 29. Epub 2019 Mar 29.

Division of Allergy and Immunology, Department of Pediatric, Children's Hospital of Philadelphia, Philadelphia, Pa; Perelman School of Medicine, The University of Pennsylvania, Philadelphia, Pa.

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http://dx.doi.org/10.1016/j.anai.2019.03.025DOI Listing
March 2019
1 Read

IgE-Mediated Multimorbidities in Allergic Asthma and the Potential for Omalizumab Therapy.

J Allergy Clin Immunol Pract 2019 Mar 27. Epub 2019 Mar 27.

Division of Infection, Immunity & Respiratory Medicine, University of Manchester, Manchester, United Kingdom; Allergy Department, 2nd Pediatric Clinic, University of Athens, Athens, Greece.

Allergic asthma often coexists with different pathological conditions, called multimorbidities, that are mostly of allergic nature and share a common underlying inflammatory pathophysiological mechanism. Multimorbidities of allergic asthma may influence asthma control, its severity, and patients' response to treatment, and contribute to the overall socioeconomic burden of the disease. Immunoglobulin E (IgE) is known to play a central role in the pathogenesis of various allergic diseases, including asthma. Read More

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http://dx.doi.org/10.1016/j.jaip.2019.02.030DOI Listing
March 2019
2 Reads

Walnut oral immunotherapy for desensitisation of walnut and additional tree nut allergies (Nut CRACKER): a single-centre, prospective cohort study.

Lancet Child Adolesc Health 2019 May 27;3(5):312-321. Epub 2019 Mar 27.

Institute of Allergy, Immunology, and Paediatric Pulmonology, Yitzhak Shamir Medical Centre, Beer Yaakov, Israel.

Background: The safety and efficacy of oral immunotherapy for tree nut allergy has not been demonstrated to date, and its effectiveness is complicated by the high prevalence of co-allergies to several nuts. This study aimed to investigate the use of walnut oral immunotherapy in the desensitisation of walnut and additional tree nuts in patients who are co-allergic to several nuts.

Methods: In a single-centre, prospective cohort study (the Nut Co-Reactivity ACquiring Knowledge for Elimination Recommendations study) at the Institute of Allergy, Immunology, and Paediatric Pulmonology at the Yitzhak Shamir Medical Centre, we recruited patients aged 4 years or older who were allergic to walnut, with or without co-allergy to pecan, hazelnut, and cashew. Read More

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http://dx.doi.org/10.1016/S2352-4642(19)30029-XDOI Listing
May 2019
3 Reads

Beneficial effects and potential risks of tomato consumption for human health: An overview.

Nutrition 2019 Jan 25;62:201-208. Epub 2019 Jan 25.

Food Safety Research Center (salt), Semnan University of Medical Sciences, Semnan, Iran; Institute for Research and Innovation in Health (i3S), University of Porto, Porto, Portugal. Electronic address:

Tomato and its derived products have a very interesting nutritional value in addition to prominent antioxidant, anti-inflammatory, and anticancer activities. In terms of tomatoes are generally quite safe to eat. However, overall consumption varies from individual to individual. Read More

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http://dx.doi.org/10.1016/j.nut.2019.01.012DOI Listing
January 2019
2 Reads
2.926 Impact Factor

Gut Prevotella as a possible biomarker of diet and its eubiotic versus dysbiotic roles-A comprehensive literature review.

Br J Nutr 2019 Mar 29:1-24. Epub 2019 Mar 29.

Faculty of Food Science and Technology,Institute of Life Sciences,University of Agricultural Sciences and Veterinary Medicine,Cluj-Napoca, CJ,Romania.

Gut microbiota has a profound impact on human health. Emerging data shows that dietary patterns are associated with different communities of bacterial species within the gut. Prevotella species have been correlated with plant rich diets, abundant in carbohydrates and fibres. Read More

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http://dx.doi.org/10.1017/S0007114519000680DOI Listing
March 2019
2 Reads

Quercetin Attenuates Visceral Hypersensitivity and 5-Hydroxytryptamine Availability in Postinflammatory Irritable Bowel Syndrome Rats: Role of Enterochromaffin Cells in the Colon.

J Med Food 2019 Mar 28. Epub 2019 Mar 28.

4 Lab of Brain and Gut Research, School of Chinese Medicine, Hong Kong Baptist University, Hong Kong, China.

Intestinal enterochromaffin (EC) cell hyperplasia and increased 5-hydroxytryptamine (5-HT) availability play key roles in the pathogenesis of abdominal hypersensitivity of irritable bowel syndrome (IBS). This study aims to study the effect of quercetin on visceral pain and 5-HT availability in postinflammatory IBS (PI-IBS) rats. PI-IBS model rats were administered quercetin by gavage at doses of 5, 10, and 20 mg/kg for 14 days. Read More

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http://dx.doi.org/10.1089/jmf.2018.4264DOI Listing

Adverse drug reaction causality assessment tools for drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis: room for improvement.

Eur J Clin Pharmacol 2019 Mar 27. Epub 2019 Mar 27.

Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.

Purpose: Establishment of causality between drug exposure and adverse drug reactions (ADR) is challenging even for serious ADRs such as Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN). Several causality assessment tools (CAT) exist, but the reliability and validity of such tools is variable. The objective of this study was to compare the reliability and validity of existing ADR CATs on SJS/TEN cases. Read More

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http://link.springer.com/10.1007/s00228-019-02670-9
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http://dx.doi.org/10.1007/s00228-019-02670-9DOI Listing
March 2019
3 Reads
2.966 Impact Factor

[Actual status of children with food allergies and food provision at residential nurseries and children's care homes: Comparison of groups using and not using guidelines or manuals].

Nihon Koshu Eisei Zasshi 2019 ;66(3):138-150

Kansai University, Faculty of Health and Well-being.

Objectives To elucidate the actual status of children with food allergies and the measures of allergy-appropriate food provisions at residential nurseries and children's care homes. We also compared institutions that used guidelines, manuals, etc. with those that did not. Read More

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http://dx.doi.org/10.11236/jph.66.3_138DOI Listing
April 2019
1 Read

Anaesthetic management of patients with pre-existing allergic conditions: a narrative review.

Br J Anaesth 2019 Mar 12. Epub 2019 Mar 12.

Department of Anaesthesia and Peri-operative Medicine, Auckland City Hospital, Auckland, New Zealand.

This narrative review seeks to distinguish the clinical patterns of pre-existing allergic conditions from other confounding non-allergic clinical entities, and to identify the potential related risks and facilitate their perioperative management. Follow-up investigation should be performed after a perioperative immediate hypersensitivity to establish a diagnosis and provide advice for subsequent anaesthetics, the main risk factor for perioperative immunoglobulin E (IgE)-mediated anaphylaxis being a previous uninvestigated perioperative immediate hypersensitivity reaction. The concept of cross-reactivity between drugs used in the perioperative setting and food is often quoted, but usually not supported by evidence. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00070912193006
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http://dx.doi.org/10.1016/j.bja.2019.01.020DOI Listing
March 2019
7 Reads

Micronutrients in Atopic Dermatitis: A Systematic Review.

J Altern Complement Med 2019 Mar 26. Epub 2019 Mar 26.

4 Division of Dermatology, Department of Medicine, University of Arizona-Tucson, Tucson, AZ.

Objective: The pathophysiology of atopic dermatitis (AD) involves a complex interplay between immune system dysfunction, genetics, and environmental factors. It is well known that nutritional status is essential to a proper functioning immune system, leading to a highly debated question regarding the role of dietary factors in the pathogenesis of AD. Food allergies and elimination diets have been broadly studied in atopy; however, less consideration has been given to how vitamins, minerals, and other micronutrients influence the risk for AD and severity of symptoms. Read More

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http://dx.doi.org/10.1089/acm.2018.0363DOI Listing
March 2019
4 Reads
1.518 Impact Factor

Advances in Molecular Mechanisms of Wheat Allergenicity in Animal Models: A Comprehensive Review.

Molecules 2019 Mar 22;24(6). Epub 2019 Mar 22.

Department of Food Science and Human Nutrition, Food Allergy & Immunology Laboratory, Michigan State University, East Lansing, MI 48824, USA.

The prevalence of wheat allergy has reached significant levels in many countries. Therefore, wheat is a major global food safety and public health issue. Animal models serve as critical tools to advance the understanding of the mechanisms of wheat allergenicity to develop preventive and control methods. Read More

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http://dx.doi.org/10.3390/molecules24061142DOI Listing
March 2019
2 Reads

An insight into toxicity and human-health-related adverse consequences of cosmeceuticals - A review.

Sci Total Environ 2019 Mar 20;670:555-568. Epub 2019 Mar 20.

Tecnologico de Monterrey, School of Engineering and Sciences, Campus Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L. CP 64849, Mexico. Electronic address:

In recent years, the use of cosmeceutical-based personal care and beauty products has ever increased, around the world. Currently, an increasing number of compounds are being assimilated in the formulation of cosmetic products as preservatives, fragrances, surfactants, etc. to intensify the performance, quality, value, and lifespan of cosmetics. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00489697193125
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http://dx.doi.org/10.1016/j.scitotenv.2019.03.261DOI Listing
March 2019
10 Reads

Factors associated with college students' willingness and readiness to act in a food allergic emergency (WilRAFAE).

Authors:
Olga Kagan

J Am Coll Health 2019 Mar 25:1-10. Epub 2019 Mar 25.

a Rockville Centre , Molloy College , New York, USA.

Objective: Food allergies are on the rise in the U.S. Factors associated with willingness and readiness to act in a food allergic emergency on a college campus are currently unknown. Read More

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http://dx.doi.org/10.1080/07448481.2019.1577868DOI Listing
March 2019
1 Read

Attenuation of allergic responses following treatment with resveratrol in anaphylactic models and IgE-mediated mast cells.

Food Funct 2019 Apr 25;10(4):2030-2039. Epub 2019 Mar 25.

College of Food and Biological Engineering, Xiamen Key Laboratory of Marine Functional Food, Fujian Provincial Engineering Technology Research Center of Marine Functional Food, Fujian Collaborative Innovation Center for Exploitation and Utilization of Marine Biological Resources, Jimei University, 43 Yindou Road, Xiamen, 361021, Fujian, P.R. China.

Resveratrol exists widely in plant species and has a variety of anti-oxidant, anti-inflammatory, and immunomodulatory properties. However, there have been few reports regarding its anti-food allergic activity. In this study, we demonstrated that resveratrol (isolated from Abies georgei) could decrease the release of β-hexosaminidase and histamine in rat basophilic leukemia-2H3 cells. Read More

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http://dx.doi.org/10.1039/c9fo00077aDOI Listing
April 2019
1 Read

[Clinical features of cow's milk protein allergy in infants presenting mainly with gastrointestinal symptoms: an analysis of 280 cases].

Zhongguo Dang Dai Er Ke Za Zhi 2019 Mar;21(3):271-276

Department of Gastroenterology, Shenzhen Children's Hospital, Shantou University Medical College, Shenzhen, Guangdong 518036, China.

Objective: To investigate the epidemiological and clinical features of cow's milk protein allergy (CMPA) in infants presenting mainly with gastrointestinal symptoms.

Methods: A retrospective analysis was performed for the clinical data of 280 hospitalized infants, who were diagnosed with CMPA presenting mainly with gastrointestinal symptoms.

Results: Among the 280 infants, 203 infants(72. Read More

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March 2019
1 Read

Helminth therapy for autism under gut-brain axis- hypothesis.

Med Hypotheses 2019 Apr 19;125:110-118. Epub 2019 Feb 19.

Department of Pathology and Laboratory Medicine, UC Davis School of Medicine; Institute for Pediatric Regenerative Medicine and Shriners Hospitals for Children of Northern California, United States. Electronic address:

Autism is a neurodevelopmental disease included within Autism Syndrome Disorder (ASD) spectrum. ASD has been linked to a series of genes that play a role in immune response function and patients with autism, commonly suffer from immune-related comorbidities. Despite the complex pathophysiology of autism, Gut-brain axis is gaining strength in the understanding of several neurological disorders. Read More

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http://dx.doi.org/10.1016/j.mehy.2019.02.042DOI Listing
April 2019
1 Read

Energy Landscapes of Ligand Motion Inside the Tunnel-Like Cavity of Lipid Transfer Proteins: The Case of the Pru p 3 Allergen.

Int J Mol Sci 2019 Mar 21;20(6). Epub 2019 Mar 21.

Universidad Politécnica de Madrid (UPM), Centro de Biotecnología y Genómica de Plantas (CBGP, UPM-INIA), Campus Montegancedo-UPM, 28223 Pozuelo de Alarcón, Madrid, Spain.

Allergies are a widespread problem in western countries, affecting a large part of the population, with levels of prevalence increasingly rising due to reasons still not understood. Evidence accumulated in recent years points to an essential role played by ligands of allergen proteins in the sensitization phase of allergies. In this regard, we recently identified the natural ligand of Pru p 3, a lipid transfer protein, a major allergen from peach fruit and a model of food allergy. Read More

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http://dx.doi.org/10.3390/ijms20061432DOI Listing
March 2019
1 Read

Food allergy in adults: substantial variation in prevalence and causative foods across Europe.

J Allergy Clin Immunol Pract 2019 Mar 18. Epub 2019 Mar 18.

Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, The Netherlands.

Background: The EuroPrevall study showed that prevalence of self-reported food allergy (FA) in adults across Europe ranged from 2-37% for any food and 1-19% for 24 selected foods.

Objective: To determine prevalence of probable FA (symptoms plus sIgE-sensitisation) and challenge-confirmed FA in European adults, along with symptoms and causative foods.

Methods: In phase I of the EuroPrevall project, a screening questionnaire was sent to a random sample of the general adult population in eight European centres. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22132198193026
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http://dx.doi.org/10.1016/j.jaip.2019.02.044DOI Listing
March 2019
3 Reads

Caprate Modulates Intestinal Barrier Function in Porcine Peyer's Patch Follicle-Associated Epithelium.

Int J Mol Sci 2019 Mar 20;20(6). Epub 2019 Mar 20.

Institute of Veterinary Physiology, Department of Veterinary Medicine, Freie Universität Berlin, 14163 Berlin, Germany.

Background: Many food components influence intestinal epithelial barrier properties and might therefore also affect susceptibility to the development of food allergies. Such allergies are triggered by increased antibody production initiated in Peyer's patches (PP). Usually, the presentation of antigens in the lumen of the gut to the immune cells of the PP is strongly regulated by the follicle-associated epithelium (FAE) that covers the PP. Read More

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http://dx.doi.org/10.3390/ijms20061418DOI Listing
March 2019
2 Reads

Comorbidities Associated with Severity of Atopic Dermatitis in Young Adult Males: A National Cohort Study.

Acta Derm Venereol 2019 Mar 21. Epub 2019 Mar 21.

Department of Dermatology, Singapore Armed Forces, Singapore, Singapore.

Atopic dermatitis (AD) is a systemic inflammatory disorder. However, the relationship between severity of AD and metabolic and atopic conditions is not well studied. The aim of this study was to elucidate the relationship between severity of AD and comorbidities, such as metabolic conditions (increased body mass index, hypertension, hyperlipidaemia, and type II diabetes mellitus) and other atopic manifestations (allergic rhinitis, asthma and food allergies). Read More

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http://dx.doi.org/10.2340/00015555-3175DOI Listing
March 2019
4 Reads

Anaphylactic Reactions in the Emergency Department of a Portuguese Tertiary Hospital: Clinical Characterization and Disease Notification.

Acta Med Port 2019 Feb 28;32(2):91-100. Epub 2019 Feb 28.

Unidade de Cuidados Intensivos Polivalente. Hospital de Santo António. Centro Hospitalar Universitário do Porto. Porto. Portugal.

Introduction: Anaphylaxis is significantly underdiagnosed, and the medical community's knowledge about it is precarious. The aim of this study is to characterize the patient population and the Emergency Department approach of anaphylaxis.

Material And Methods: Retrospective study of adult patients attending the Emergency Department of a tertiary care Portuguese hospital, over a year, with anaphylaxis. Read More

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http://dx.doi.org/10.20344/amp.10820DOI Listing
February 2019
3 Reads

The association between allergic diseases and cancer: a systematic review of the literature.

Neth J Med 2019 Feb;77(2):42-66

Department of Internal Medicine, Section Allergy and Clinical Immunology, Erasmus Medical Center Rotterdam, the Netherlands.

Introduction: Atopic syndrome (allergic rhinitis, asthma and eczema) and food allergies are frequently reported, especially in developed countries. Studies have previously suggested an inverse association between allergic diseases and cancer. The aim of this study was to investigate the association between allergic diseases and different types of cancers by performing a systematic review of the literature. Read More

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February 2019
2 Reads

A Novel Double-Blind, Placebo-Controlled Food Challenge Matrix for Milk and Raw Egg.

Int Arch Allergy Immunol 2019 Mar 20:1-9. Epub 2019 Mar 20.

Department of Dermatology, Faculty of Medicine and Health Science, Ghent University, Ghent, Belgium.

Background: The double-blind, placebo-controlled food challenge (DBPCFC) is still considered to be the gold standard in food allergy diagnosis. This test is however not common practice in routine due to several practical limitations, especially for non-IgE-mediated food allergy with its typical delayed food allergic reactions.

Objective: The aim of this study was to develop and evaluate DBPCFC matrices for the diagnosis of milk and egg allergies which can be applied at home for the diagnosis of delayed food allergic reactions. Read More

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https://www.karger.com/Article/FullText/494622
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http://dx.doi.org/10.1159/000494622DOI Listing
March 2019
4 Reads