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    Food protein-induced enterocolitis syndrome by fish: Not necessarily a restricted diet.
    Allergy 2017 Oct 20. Epub 2017 Oct 20.
    Paediatric Allergy Unit. Hospital Infantil Universitario Gregorio Marañón, Madrid, Spain.
    Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated gastrointestinal food hypersensitivity usually due to cow's milk or soy. Recent researches show that fish is one of the most important triggers of FPIES in the Mediterranean countries. Due to the risk of multiple-food-FPIES, avoiding foods in the same category or that often occur together may be reasonable. Read More

    [Effects of ovalbumin exposure during pregnancy of mice on the ovalbumin re-exposure in adult progeny].
    Zhonghua Er Ke Za Zhi 2017 Oct;55(10):766-770
    Department of Child Health Care, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing Key Laboratory of Pediatrics, Chongqing 400014, China.
    Objective: To observe the immunoreaction of offspring mice by ovalbumin (OVA) re-exposure after their mothers exposed to OVA during pregnancy. Method: A prospective controlled study was conducted to observe mice after repeated OVA exposures at 6-8 weeks.Their mothers were exposed to OVA during different stages of pregnancy. Read More

    The role of intravenous access during oral food challenges in food protein-induced enterocolitis syndrome.
    Allergy Asthma Proc 2017 Nov;38(6):467-473
    Background: Food protein-induced enterocolitis syndrome (FPIES) is a non-immunoglobulin E mediated food hypersensitivity syndrome characterized by profuse vomiting and diarrhea, which leads to lethargy, dehydration, and hypotension. Given the potential severity of reactions, resolution of FPIES is confirmed via oral food challenge (OFC) during which intravenous (IV) access is recommended to facilitate IV fluids (IVF) and steroid therapy. Risk factors for IV treatment are not well characterized. Read More

    [Determination of a new cow's milk-based formula allergenic capacity in 7 infants].
    Rev Alerg Mex 2017 Jul-Sep;64(3):250-259
    Universidad de Antioquia, Escuela de Nutrición y Dietética, Medellín, Antoquia, Colombia.
    Background: Cow's milk protein allergy is the main allergic problem during the first year of life, possibly owing to immune and gastrointestinal systems poor maturation. To prevent allergic reactions, the content and type of proteins in infant formulas resemble those of breast milk. We believe that reactions are due rather to the amount than to the type of protein. Read More

    Chemokine CCL8 and its Receptor CCR5 in the Spinal Cord are Involved in Visceral Pain Induced by Experimental Colitis in Mice.
    Brain Res Bull 2017 Oct 13. Epub 2017 Oct 13.
    Department of Gastroenterology, Affiliated Hospital of Jiangsu University, Jiangsu University, Zhenjiang, Jiangsu 212001, China. Electronic address:
    Visceral hypersensitivity induced by inflammatory bowel disease (IBD) is a clinical challenge since the underlying mechanisms remain elusive. Chemokines and their receptors have been suggested to modulate inflammatory pain and neuropathic pain. However, the exact chemokines involved in visceral pain remain to be determined. Read More

    Prebiotics for the prevention of allergies: a systematic review and meta-analysis of randomized controlled trials.
    Clin Exp Allergy 2017 Oct 16. Epub 2017 Oct 16.
    Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
    Background: Prevalence of allergic diseases in infants is approximately 10% reaching 20 to 30% in those with an allergic first-degree relative. Prebiotics are selectively fermented food ingredients that allow specific changes in composition/activity of the gastrointestinal microflora. They modulate immune responses and their supplementation has been proposed as an intervention to prevent allergies. Read More

    Bronchial thermoplasty and the role of airway smooth muscle: are we on the right direction?
    Ther Clin Risk Manag 2017 19;13:1213-1221. Epub 2017 Sep 19.
    Department of Medical Specialties, Pneumology Unit, IRCCS - Arcispedale Santa Maria Nuova, Reggio Emilia.
    Asthma is characterized by inflammation of the airways that includes eosinophils, basal membrane thickening, epithelial sloughing, vascular changes, smooth muscle hypertrophy and hyperplasia, and mucous gland hyperplasia. Recently, there have been studies on the role of hypersensitivity and inflammation in asthma, but the role of bronchial smooth muscle remains unclear. Bronchial thermoplasty is an endoscopic procedure that is approved by the US Food and Drug Administration (FDA) for the treatment of severe refractory asthma, based on the local delivery of radio frequency at 65°C to the airways, with the aim of controlling bronchospasm through a reduction of airway smooth muscle (ASM). Read More

    Validation of a Spanish version of the EuroPrevall Food Allergy Quality of Life Questionnaire-Parental Form.
    Allergol Immunopathol (Madr) 2017 Oct 12. Epub 2017 Oct 12.
    Unit of Pediatric Allergy and Pneumology, Instituto de Investigación Sanitaria, Hospital Universitario y Politécnico La Fe, Valencia, Spain. Electronic address:
    Background: Food allergy can have a major impact on quality of life of children and their parents. Questionnaires have been developed to measure the impact of this disorder. We aimed to validate the EuroPrevall questionnaire on Food Allergy-Quality of Life Questionnaire, Parent Form (FAQLQ-PF) and the Food Allergy Independent Measure (FAIM), translated into Spanish. Read More

    Low efficacy of atopy patch test in predicting tolerance development in non-IgE-mediated cow's milk allergy.
    Allergol Immunopathol (Madr) 2017 Oct 11. Epub 2017 Oct 11.
    Food Allergy Research Group, Pediatrics Department, Universidade Federal de Uberlandia, Brazil. Electronic address:
    Background: The food atopy patch (APT) test has been used in previous studies to help the diagnosis of non-IgE mediated food allergies (FA). The aim of this study was to evaluate the efficacy of different cow's milk APT preparations to predict oral tolerance in children with previous non-IgE-mediated cow's milk allergy (CMA) diagnosis.

    Methods: Thirty-two patients non-IgE-mediated CMA diagnosed by oral food challenge (OFC) were enrolled to perform APT with three different cow's milk preparations (fresh, 2% in saline solution, 2% in petrolatum) and comparing with a new OFC after at least three months of diet exclusion. Read More

    On the metabolites produced by Colletotrichum gloeosporioides a fungus proposed for the Ambrosia artemisiifolia biocontrol; spectroscopic data and absolute configuration assignment of colletochlorin A.
    Nat Prod Res 2017 Oct 13:1-11. Epub 2017 Oct 13.
    a Department of Chemical Sciences , University of Naples Federico II, Complesso Universitario Monte S. Angelo , Napoli , Italy.
    Ambrosia artemisiifolia L. is responsible for serious allergies induced on humans. Different approaches for its control were proposed during the COST Action FA1203 "Sustainable management of Ambrosia artemisiifolia in Europe" (SMARTER). Read More

    Association between childhood allergic diseases, educational attainment and occupational status in later life: systematic review protocol.
    BMJ Open 2017 Oct 11;7(10):e017245. Epub 2017 Oct 11.
    London School of Hygiene & Tropical Medicine, London, UK.
    Introduction: Childhood allergic diseases may prevent affected children from achieving their academic potential. Potential mechanisms include absence from school due to illness and medical appointments. Experience of symptoms in classes or leisure time, and stigma associated with visible signs and symptoms, including skin disease, requirements for medication during school time or the need for specific diets, may also contribute to reduced educational attainment. Read More

    Respiratory comorbidity in South African children with atopic dermatitis.
    S Afr Med J 2017 Sep 22;107(10):904-909. Epub 2017 Sep 22.
    Division of Allergology, Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, Cape Town, and Faculty of Health Sciences, University of Cape Town, South Africa.
    Background: Atopic dermatitis (AD) is an early and important step in the propagation of the allergic march, enhancing food and respiratory allergies via epicutaneous sensitisation to allergens.

    Objectives: To determine the prevalence and patterns of aeroallergen sensitisation, asthma and allergic rhinitis in South African (SA) children with AD.

    Methods: This was a prospective, observational study in a paediatric university hospital in Cape Town, SA. Read More

    Effect of pre-harvest and post-harvest conditions on the fruit allergenicity:A review.
    Crit Rev Food Sci Nutr 2017 Oct 11. Epub 2017 Oct 11.
    a Department of Bioresource Engineering , Faculty of Agricultural and Environmental Sciences, McGill University, Sainte-Anne-de-Bellevue, Quebec H9 × 3V9 , Canada.
    Fruits are an important source of vitamins and antioxidants that can effectively delay aging and contribute to health and well-being of the human kind. However, they are growing to be one of the primary elicitors of food allergies around the world. Fruit allergens can induce an IgE-mediated (Immunoglobulin E) reaction, presenting with a symptom like localized oral allergy syndrome (OAS). Read More

    A preliminary study of gut dysbiosis in children with food allergy.
    Biosci Biotechnol Biochem 2017 Oct 11:1-4. Epub 2017 Oct 11.
    c Kyoto Institute of Nutrition and Pathology , Kyoto , Japan.
    Gut microbiota of food allergic children was analyzed by high throughput 16S rRNA gene sequencing. Signs of gut dysbiosis, which is likely associated with gut inflammation, was observed in children with food allergies. For example, decreased abundance of genus Akkermansia but increased abundance of Veillonella was found in children with food allergy in comparison with healthy control children. Read More

    Anorexia: Anormal Phobia of Normal Weight.
    Pril (Makedon Akad Nauk Umet Odd Med Nauki) 2017 Sep;38(2):45-53
    Anorexia nervosa is a disorder of feeding behavior associated with distortion of body image, mood disturbance and a wide variety of hormonal and metabolic abnormalities. It is supposed that the disease could be the consequence of a combination of cultural-social, psychological and biological factors. Our study confirmed that anorexia mentalis is a serious, life threatening disorder which in our country appears earlier than it was expected and that is strongly related to environmental factors (family, school, fashion, society). Read More

    Early microbiota, antibiotics and health.
    Cell Mol Life Sci 2017 Oct 7. Epub 2017 Oct 7.
    Department of Microbiology and Biochemistry of Dairy Products, Instituto de Productos Lácteos de Asturias, Consejo Superior de Investigaciones Científicas (IPLA-CSIC), Paseo Rio Linares s/n, 33300, Villaviciosa, Asturias, Spain.
    The colonization of the neonatal digestive tract provides a microbial stimulus required for an adequate maturation towards the physiological homeostasis of the host. This colonization, which is affected by several factors, begins with facultative anaerobes and continues with anaerobic genera. Accumulating evidence underlines the key role of the early neonatal period for this microbiota-induced maturation, being a key determinant factor for later health. Read More

    Non-coeliac gluten or wheat sensitivity: emerging disease or misdiagnosis?
    Med J Aust 2017 Aug;207(5):211-215
    University of Newcastle, Newcastle, NSW.
    Non-coeliac gluten or wheat sensitivity (NCG/WS) is a condition characterised by adverse gastrointestinal and/or extra-intestinal symptoms associated with the ingestion of gluten- or wheat-containing foods, in the absence of coeliac disease or wheat allergy. Up to one in 100 people in Australia may have coeliac disease but many more report adverse gastrointestinal and/or extra-intestinal symptoms after eating wheat products. In the absence of validated biomarkers, a diagnosis of NCG/WS can only be made by a double-blind, placebo-controlled, dietary crossover challenge with gluten, which is difficult to apply in clinical practice. Read More

    Physician's appraisal versus documented signs and symptoms in the interpretation of food challenge tests: the EuroPrevall birth cohort.
    Pediatr Allergy Immunol 2017 Oct 6. Epub 2017 Oct 6.
    Department of Pediatric Pneumology and Immunology.
    Background: Blinded food challenges are considered the current gold standard for the diagnosis of food allergies. We used data from a pan-European multicentre project to assess differences between study centres, aiming to identify the impact of subjective aspects for the interpretation of oral food challenges.

    Methods: Nine study centres of the EuroPrevall birth cohort study on food allergy recruited 12,049 newborns and followed them for up to 30 months in regular intervals. Read More

    Functional heterogeneity of gut-resident regulatory T cells.
    Clin Transl Immunology 2017 Sep 22;6(9):e156. Epub 2017 Sep 22.
    Institute for Medical Microbiology and Hygiene, Philipps University of Marburg, Marburg, Germany.
    Regulatory T cells (Treg cells) have a central role in the maintenance of intestinal homeostasis by restraining inappropriate immune responses in the healthy gut. Although distinct intestinal immune cell populations have been described to exhibit regulatory activity, several genetic and functional studies provided a strong evidence for a pivotal role of forkhead box P3 (Foxp3)(+)CD4(+) Treg cells in prevention of dysregulated mucosal immune reactions and development of chronic immunological disorders such as celiac disease, food allergies and inflammatory bowel disease. Treg cells provide an important layer of intestinal defense by suppressing immune responses against innocuous food and commensal-derived antigens. Read More

    Lakartidningen 2017 Oct 2;114. Epub 2017 Oct 2.
    Skanes universitetssjukhus Lund - Lung- och Allergisektionen Lund, Sweden Skanes universitetssjukhus Lund - Lung- och Allergisektionen Lund, Sweden.
    Cinnamon rolls triggered anaphylactic reaction. The genesis could be wheat-dependent exercise-induced anaphylaxis Two case reports from our Department of Allergology illustrate the wheat-dependent exercise-induced anaphylaxis (WDEIA), which is a relatively rare, yet potentially fatal form of food allergy. Wheat (Triticum aestivum) is the most commonly grown crop world-wide, and some individuals cannot tolerate it due to wheat hypersensitivity. Read More

    CGRPα within the Trpv1-Cre population contributes to visceral nociception.
    Am J Physiol Gastrointest Liver Physiol 2017 Sep 28:ajpgi.00188.2017. Epub 2017 Sep 28.
    University of Uppsala.
    The role of Calcitonin Gene Related Peptide (CGRP) in visceral and somatic nociception is incompletely understood. CGRPα is highly expressed in sensory neurons of dorsal root ganglia (DRG) and particularly in neurons that also express the transient receptor potential cation channel subfamily V member 1 (Trpv1). Therefore, we investigated changes in visceral and somatic nociception following deletion of CGRPα from the Trpv1-Cre population using the Cre/lox system. Read More

    Pattern of Allergen Sensitivity among Patients with Bronchial Asthma and/or Allergic Rhinosinusitis in a Tertiary Care Centre of Southern India.
    J Clin Diagn Res 2017 Aug 1;11(8):OC01-OC04. Epub 2017 Aug 1.
    Associate Professor, Department of Pulmonary Medicine, Kasturba Medical College, Manipal University, Mangalore, Karnataka, India.
    Introduction: The distribution of aeroallergens varies among various geographical areas of India and the knowledge of allergen sensitivity pattern in this part of Southern Indian (Karnataka) is limited. This data can provide clinically useful information and better understanding of common allergies prevalent in this area.

    Aim: To study the pattern of allergen sensitivity among patients with bronchial asthma and/or allergic rhinosinusitis. Read More

    [Profile of gastrointestinal diseases in a pediatric gastroenterology center in Colombia: 15 years of follow-up].
    Biomedica 2017 Sep 1;37(3):315-323. Epub 2017 Sep 1.
    Facultad de Medicina, posgrado de Gastroenterología Pediátrica y Pediatría, Universidad El Bosque, Bogotá, D.C., Colombia Grupo de Investigación Gastronutriped, Unidad de Gastroenterología, Hepatología y Nutrición Pediátrica-Gastronutriped, Bogotá, D.C., Colombia.
    Introduction: The profile of gastrointestinal diseases is constantly changing globally and locally affecting suspected diagnosis and medical methods.

    Objective: To establish the main diagnoses in a gastroenterology, hepatology, and pediatric nutrition unit in Bogota between 2009 and 2013, and to compare with findings from the same unit during the two prior five-year periods (1997 to 2006).

    Materials And Methods: We conducted a retrospective descriptive study. Read More

    Advances in Food Allergy.
    Otolaryngol Clin North Am 2017 Sep 27. Epub 2017 Sep 27.
    Department of Otolaryngology-Head and Neck Surgery, University of Missouri Medical Center-Columbia, One Hospital Drive, MA314, Columbia, MO 65212, USA. Electronic address:
    Food allergy has been increasing in prevalence for the last few decades, and numerous studies have evaluated ways of improving the allergy practitioner's ability to accurately diagnose patients who are truly food allergic, rather than sensitive but able to tolerate food. Once diagnosed, the current standard treatment is food elimination and avoidance, but other potential treatment options like oral immunotherapy, sublingual immunotherapy, and epicutaneous immunotherapy are becoming promising alternatives. Due the health care costs and potential for life-threatening adverse reactions, much attention has been given to the prevention of food allergies, resulting a shift in recent guideline recommendations. Read More

    Anti-Inflammatory Thioredoxin Family Proteins for Medicare, Healthcare and Aging Care.
    Nutrients 2017 Sep 29;9(10). Epub 2017 Sep 29.
    Japan Biostress Research Promotion Alliance (JBPA), 1-6 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8397, Japan.
    Human thioredoxin (TRX) is a 12-kDa protein with redox-active dithiol in the active site -Cys-Gly-Pro-Cys-, which is induced by biological stress due to oxidative damage, metabolic dysfunction, chemicals, infection/inflammation, irradiation, or hypoxia/ischemia-reperfusion. Our research has demonstrated that exogenous TRX is effective in a wide variety of inflammatory diseases, including viral pneumonia, acute lung injury, gastric injury, and dermatitis, as well as in the prevention and amelioration of food allergies. Preclinical and clinical studies using recombinant TRX (rhTRX) are now underway. Read More

    Treatment of gastric eosinophilia by epicutaneous immunotherapy in piglets sensitized to peanuts.
    Clin Exp Allergy 2017 Sep 28. Epub 2017 Sep 28.
    Hôpital Necker, Université Paris-Descartes, Paris, France.
    Background: Eosinophilic gastrointestinal disorders (EGIDs) are hypersensitivity disorders frequently triggered by food allergy and manifested by mucosal eosinophilic infiltration at any level of the gastrointestinal tract. This study established a model of gastric eosinophilia in peanut-sensitized piglets to evaluate the efficacy of epicutaneous immunotherapy (EPIT) for its treatment.

    Methods: Experiments were carried out in piglets first sensitized by three intra-peritoneal injections of peanut protein extract (PPE) with adjuvant, and then given PPE orally for 10 days, a sequence leading to gastric eosinophilia assessed by endoscopy. Read More

    Development of IgE-mediated immediate hypersensitivity to a previously tolerated food following its avoidance for eosinophilic gastrointestinal diseases.
    J Allergy Clin Immunol Pract 2017 Sep 22. Epub 2017 Sep 22.
    Pediatric Allergy and Immunology, Icahn School of Medicine at Mount Sinai, New York, NY; Mount Sinai Center for Eosinophilic Disorders, Icahn School of Medicine at Mount Sinai, New York, NY. Electronic address:

    Influence of enzymatic hydrolysis on the allergenic reactivity of processed cashew and pistachio.
    Food Chem 2018 Feb 2;241:372-379. Epub 2017 Sep 2.
    U.S. Department of Agriculture, Agricultural Research Service, Southern Regional Research Center, 1100 Robert E. Lee Blvd., New Orleans, LA 70124, USA.
    Cashew and pistachio allergies are considered a serious health problem. Previous studies have shown that thermal processing, pressurization and enzymatic hydrolysis may reduce the allergenic properties of food by changing the protein structure. This study assesses the allergenic properties of cashew and pistachio after thermal treatment (boiling and autoclaving), with or without pressure (autoclaving), and multiple enzymatic treatments under sonication, by SDS-PAGE, western blot and ELISA, with serum IgE of allergic individuals, and mass spectroscopy. Read More

    Unrecognized Sleep Loss Accumulated in Daily Life Can Promote Brain Hyperreactivity to Food Cue.
    Sleep 2017 Oct;40(10)
    Department of Psychophysiology, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawa-Higashi, Kodaira, Tokyo 187-8553, Japan.
    Epidemiological studies have shown that sleep debt increases the risk of obesity. Experimental total sleep deprivation (TSD) has been reported to activate the reward system in response to food stimuli, but food-related responses in everyday sleep habits, which could lead to obesity, have not been addressed. Here, we report that habitual sleep time at home among volunteers without any sleep concerns was shorter than their optimal sleep time estimated by the 9-day extended sleep intervention, which indicates that participants had already been in sleep debt in their usual sleep habits. Read More

    Citrus essential oils: Extraction, authentication and application in food preservation.
    Crit Rev Food Sci Nutr 2017 Sep 28. Epub 2017 Sep 28.
    a School of Chemical Engineering, Yeungnam University , Gyeongsan , Republic of Korea -38541.
    Citrus EOs is an economic, eco-friendly and natural alternatives to chemical preservatives and other synthetic antioxidants, such as sodium nitrites, nitrates or benzoates, commonly utilized in food preservation. Citrus based EOs is obtained mainly from the peels of citrus fruits which are largely discarded as wastes and cause environmental problems. The extraction of citrus oils from the waste peels not only saves environment but can be used in various applications including food preservation. Read More

    Interoceptive contributions to healthy eating and obesity.
    Curr Opin Psychol 2017 Oct 8;17:106-112. Epub 2017 Jul 8.
    Laureate Institute for Brain Research, 6655 South Yale Ave., Tulsa, OK 74136-3326, United States; Department of Psychology, University of Tulsa, Tulsa, OK, United States.
    Obesity results from persistent failure by the brain to balance food intake with energy needs, resulting in a state of chronic energy surplus. Although there are many factors that predispose individuals to weight gain and obesity, the current review focuses on two ways eating behavior may be influenced by sensitivity to interoceptive signals of hunger, satiety, and metabolic energy reserves. First, obesity may be related to hypersensitivity to interoceptive signals of hunger, leading to positive alliesthesia for food cues that undermine attempts to change unhealthy eating behaviors. Read More

    Could Sublingual Immunotherapy Affect Oral Health in Children with Asthma and/or Allergic Rhinitis Sensitized to House Dust Mite.
    Int Arch Allergy Immunol 2017 Sep 27;174(1):52-56. Epub 2017 Sep 27.
    Department of Pediatric Allergy and Immunology, School of Medicine, Marmara University, Istanbul, Turkey.
    Background: Sublingual immunotherapy (SLIT) has been successfully employed in IgE-mediated respiratory allergies. However, it is not known whether the modulation of immune responses in the sublingual area during SLIT has any deleterious effect on oral health. We sought to determine the oral health prospectively in children receiving SLIT for house dust mite allergy. Read More

    A Mouse Model of Anaphylaxis and Atopic Dermatitis to Salt-Soluble Wheat Protein Extract.
    Int Arch Allergy Immunol 2017 Sep 27;174(1):7-16. Epub 2017 Sep 27.
    Food Allergy and Immunology Laboratory, Michigan State University, East Lansing, MI, USA.
    Background: Wheat allergy and other immune-mediated disorders triggered by wheat proteins are growing at an alarming rate for reasons not well understood. A mouse model to study hypersensitivity responses to salt-soluble wheat protein (SSWP) extract is currently unavailable. Here we tested the hypothesis that SSWP extract from wheat will induce sensitization as well as allergic disease in mice. Read More

    Effects of industrial cashew nut processing on anacardic acid content and allergen recognition by IgE.
    Food Chem 2018 Feb 27;240:370-376. Epub 2017 Jul 27.
    Embrapa Agroindústria Tropical, CEP 60511 110 Fortaleza, CE, Brazil.
    Cashew nuts are important both nutritionally and industrially, but can also cause food allergies in some individuals. The present study aimed to assess the effect(s) of industrial processing on anacardic acids and allergens present in cashew nuts. Sample analyses were performed using liquid chromatography coupled with mass spectrometry, SDS-PAGE and immunoassay. Read More

    Allergy to Peanut, Soybean, and Other Legumes: Recent Advances in Allergen Characterization, Stability to Processing and IgE Cross-Reactivity.
    Mol Nutr Food Res 2017 Sep 25. Epub 2017 Sep 25.
    Department of Dermatology and Allergy, University of Bonn Medical Center, Sigmund-Freud-Str., 25, 53127, Bonn, Germany.
    Peanut and soybean are members of the Leguminosae family. They are two of the eight foods that account for the most significant food allergies in the US and Europe. Allergic reactions to other legume species can be of importance in other regions of the world. Read More

    Sensitisation to fungi in atopic dermatitis patients over 14 years of age and the relation to the occurrence of food hypersensitivity reactions.
    Mycoses 2017 Sep 22. Epub 2017 Sep 22.
    Department of Allergy and Clinical Immunology, Outpatient Clinic, Hradec Králové, Czech Republic.
    The aim of this study was to evaluate if there is some relation between the sensitisation to fungi and the occurrence of food hypersensitivity reactions in atopic dermatitis patients aged 14 years and older. Complete dermatological and allergological examination was performed in all included patients; the occurrence of food hypersensitivity reactions was recorded and the sensitisation to mixture of fungi was examined (skin prick test, specific IgE). The statistical evaluation of the relation between the sensitisation to fungi and the occurrence of food hypersensitivity reactions was performed; 331 patients were included in the study, 110 men and 221 women, the average age was 26. Read More

    Non-IgE-mediated gastrointestinal food allergies.
    Curr Opin Pediatr 2017 Sep 20. Epub 2017 Sep 20.
    aDivision of Pediatric Allergy, Department of Pediatrics, University Hospitals of Geneva, Geneva, Switzerland bPediatric Allergy Division, Hôpital Femme-Mère-Enfant, Université de Lyon Est, Lyon, France cDivision of Pediatric Allergy, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
    Purpose Of Review: We focus on recent advances regarding the epidemiology, physiopathology, diagnosis and managements of non-IgE-mediated gastrointestinal food allergies (non-IgE-GI-FAs), particularly food protein-induced enterocolitis syndrome (FPIES).

    Recent Findings: The first international FPIES diagnostic and management guidelines have been recently published. Although FPIES largely remains a diagnosis of exclusion, it may be more prevalent than previously thought. Read More

    [Targeting the skin - erythema multiforme in dogs and cats].
    Tierarztl Prax Ausg K Kleintiere Heimtiere 2017 Oct 20;45(5):352-356. Epub 2017 Sep 20.
    Teresa Böhm, Medizinische Kleintierklinik, Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München, E-Mail:
    This review article will describe the complex nature of erythema multiforme in dogs and cats. The disease pattern will be illustrated in terms of etiology, pathogenesis, clinical signs, diagnostics and therapy. Erythema multiforme is a rare, immune-mediated skin disorder with an acute specific reaction pattern of skin and mucous membranes against different underlying causes. Read More

    Allergic shock caused by ingestion of cooked jellyfish: A case report.
    Medicine (Baltimore) 2017 Sep;96(38):e7962
    aQingdao University Medical College, Qingdao bKey Laboratory of Experimental Marine Biology, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong cEmergency Department, The Affiliated Central Hospital of Qingdao University, Qingdao dDepartment of Neurology, The Affiliated Hospital of Qingdao University, Qingdao eLaboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China.
    Rationale: Although anaphylaxis caused by jellyfish stings is common in coastal areas, an allergic shock caused by cooked jellyfish ingestion has never been reported in China. In this paper, we report a case of allergic shock being caused by ingestion of cooked salt-preserved jellyfish shortly after being stung by a live jellyfish.

    Patient Concerns: A 26-year-old Chinese man presented with dizziness, pruritus, dyspnea, hypotension, and tachycardia after eating cooked salted jellyfish. Read More

    Immunotherapy of Food Allergy: a Comprehensive Review.
    Clin Rev Allergy Immunol 2017 Sep 19. Epub 2017 Sep 19.
    Simon F.S. Li Marine Science Laboratory, School of Life Sciences, The Chinese University of Hong Kong, Room 201A, Science Park Road, Shatin, N.T., Hong Kong, SAR, China.
    Food allergy imposes a severe global health burden, and thus, there is a dire need for safe and effective treatments. Allergen-specific immunotherapy (AIT) is currently the only approach to restore immune tolerance through administrating increasing doses of allergen extracts. Unfortunately, the development of AIT for food allergies has been impeded by the frequent anaphylactic side effects during the course of treatment. Read More

    Correlation of types of food and asthma diagnosis in childhood: A case-control study.
    J Asthma 2017 Sep 19:1-9. Epub 2017 Sep 19.
    a Faculty of Pharmacy , Lebanese University , Beirut , Lebanon.
    Objective: Studies concerning asthma in Lebanon investigated environmental and personal factors but none of them took into account the effect of nutritional habits. Our objective is to assess the effect of nutritional habits on asthma and allergies in Lebanese children aged 3-16 years old.

    Methods: This is a case-control study, conducted between December 2015 and April 2016. Read More

    National allergy programme had little impact on parent-reported food allergies in children aged 6-7 years.
    Acta Paediatr 2017 Sep 19. Epub 2017 Sep 19.
    Centre for Child Health Research, Tampere University and University Hospital, Tampere, Finland.
    Aim: The ten-year Finnish national allergy programme was launched in 2008 to lessen the disease and psychological burden of allergy. This study assessed the prevalence of parent-reported food allergies requiring avoidance diets at primary school in children aged six and seven years.

    Methods: The cohort comprised 1937 children (51% boys) who started primary school in Tampere, Finland, in August 2016. Read More

    Current (food) Allergenic Risk Assessment: Is It Fit for Novel Foods? Status Quo and Identification of Gaps.
    Mol Nutr Food Res 2017 Sep 19. Epub 2017 Sep 19.
    Department of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria.
    Food allergies are recognised as a global health concern. In order to protect allergic consumers from severe symptoms, allergenic risk assessment for well known foods and foods containing genetically modified ingredients was installed. However, population is steadily growing and there is a rising need to provide adequate protein-based foods, including novel sources, not yet used for human consumption. Read More

    Passive blood anaphylaxis: subcutaneous immunoglobulins are a cause of ongoing passive anaphylactic reaction.
    Allergy Asthma Clin Immunol 2017 15;13:41. Epub 2017 Sep 15.
    Department of Immunology of Infectious Diseases, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, POBox 1818, 50-385 Wrocław-46, Poland.
    Background: Allergic, especially anaphylactic, reactions during immunoglobulin replacement therapy are rare, but their pathophysiology and classification remain ambiguous. Recent findings show positive results of skin tests with commercially available immunoglobulins, but target antigens and responsible compounds of the tested immunoglobulins have not been strictly identified.

    Case Description And Findings: Four adult patients with recently diagnosed common variable immunodeficiency qualified for standard subcutaneous immunoglobulin replacement therapy regimen. Read More

    Dietary intervention for preventing food allergy in children.
    Curr Opin Pediatr 2017 Sep 13. Epub 2017 Sep 13.
    aMurdoch Childrens Research Institute, Parkville bDepartment of Paediatrics, University of Melbourne cDepartment of Allergy and Immunology, Royal Children's Hospital, Melbourne, Victoria, Australia.
    Purpose Of Review: In the past decade, food allergy has been increasingly recognized as an important public health issue. The role of maternal and infant diet in the development of food allergy has been a major focus of research throughout this period. Recently, research in this area has moved from observational studies to intervention trials, and the findings from these trials have started to influence infant feeding guidelines. Read More

    A Retrospective Study of Korean Adults With Food Allergy: Differences in Phenotypes and Causes.
    Allergy Asthma Immunol Res 2017 Nov;9(6):534-539
    Department of Allergy and Clinical Immunology, Ajou University School of Medicine, Suwon, Korea.
    Purpose: Increasing in prevalence, food allergy (FA) is becoming an important public health concern. In Korean adults, however, clinical phenotypes and causes of FA have not been studied. We aimed to study common causative allergens and clinical manifestations of FA in Korean adults. Read More

    Latest insights on Food Protein-Induced Enterocolitis Syndrome: an emerging medical condition.
    J Investig Allergol Clin Immunol 2017 Aug 29. Epub 2017 Aug 29.
    Pediatric Allergy Department, Children's Hospital Teresa Herrera, La Coruña.
    Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE mediated gastrointestinal food hypersensitivity, characterized by profuse vomiting, frequently associated to pallor or/and lethargy that appears within 1 to 3 hours after ingestion of the offending food. There is a less frequent chronic form of FPIES, presenting with protracted vomiting, diarrhea or both, accompanied by poor growth. Although FPIES is considered a rare allergic disorder, in the last few years there have been an increasing number of reports about it indicating if not a real increase in incidence, at least an increased awareness of this condition by pediatricians. Read More

    Economic Factors Impacting Food Allergen Management: Perspectives from the Food Industry.
    J Food Prot 2017 Oct;80(10):1719-1725
    2 Northwestern University Feinberg School of Medicine, 420 East Superior Street, Chicago, Illinois 60611.
    Food allergies affect up to 8% of children in the United States and may occasionally lead to severe life-threatening reactions. Because there is currently no cure for food allergies, strict avoidance of the allergen-containing foods is the only means of preventing an allergic reaction. Consumers rely on food manufacturers to reliably track and declare the presence of food allergens in products. Read More

    Current practice of allergy diagnosis and the potential impact of regulation in Europe.
    Allergy 2017 Sep 14. Epub 2017 Sep 14.
    Department of Respiratory Diseases and Allergy, Department of Clinical Medicine, Aarhus University, Aarhus C, Denmark.
    In the European Union (EU), the regulatory framework regarding diagnostic allergen extracts is currently in the process of being implemented at the national level. Due to these regulations, the initial and periodic renewal expenses for the registration of diagnostic allergen extracts may render extract production unprofitable. Consequently, many extracts may be at risk of removal from the market. Read More

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