26,027 results match your criteria Food Allergies


A Rare Case with Quail Egg Allergy without Allergic Reactions to Oral Food Challenge with Hen's Egg White.

Iran J Allergy Asthma Immunol 2020 Jun 23;19(3):310-312. Epub 2020 Jun 23.

Department of Allergy and Clinical Immunology, Rasool-e-akram Hospital, Iran University of Medical Sciences, Tehran, Iran.

Hen's egg, as one of the most common reasons for IgE-mediated food hypersensitivity, affects both children and adults. Taking precautionary measures is suggested for the consumption of other birds' eggs for patients with allergy to hen's egg. This paper describes a rare patient with quail egg allergy, which manifested no allergic reactions after oral food challenge with hen's egg white. Read More

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http://dx.doi.org/10.18502/ijaai.v19i3.3459DOI Listing

Mechanistic insights into the anticandidal action of Vanillin reveal disruption of cell surface integrity and mitochondrial functioning.

Infect Disord Drug Targets 2020 Jul 2. Epub 2020 Jul 2.

Amity Institute of Biotechnology, Amity University Haryana, Gurugram (Manesar)-122413. India.

Background: Considering the emergence of multidrug resistance (MDR) in prevalent human fungal pathogen, Candida albicans, there is parallel spurt in development of novel strategies aimed to disrupt MDR. Compounds from natural resources could be exploited as efficient antifungal drugs owing to their structural diversity, cost effectiveness and negligible side effects.

Objective: The present study elucidates the antifungal mechanisms of Vanillin (Van), a natural food flavoring agent against Candida albicans. Read More

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http://dx.doi.org/10.2174/1871526520666200702134110DOI Listing

Dietary therapy for eosinophilic esophagitis: chances and limitations in the clinical practice.

Expert Rev Gastroenterol Hepatol 2020 Jul 2. Epub 2020 Jul 2.

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd) , Spain.

Introduction: Eosinophilic esophagitis (EoE) is a non-IgE-mediated food allergy that currently represents the main cause of dysphagia and food impaction in children and young adults. Diet remains the only therapy targeting the cause of the disease. Relevant advances in recent years allow novel approaches to dietary therapy in EoE. Read More

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http://dx.doi.org/10.1080/17474124.2020.1791084DOI Listing

Study on immunoregulation function of peony seed proteolysis product in mice.

J Food Biochem 2020 Jul 2:e13353. Epub 2020 Jul 2.

College of Food and Bioengineering, Henan University of Science and Technology, Luoyang, P.R. China.

To explore the immunoregulatory function of peony seed proteolysis product in mice, the protein from peony seed meal was extracted and hydrolyzed with bromelain. The peony seed proteolysis product was fed to mice at three different doses of 0.25, 0. Read More

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http://dx.doi.org/10.1111/jfbc.13353DOI Listing

Association between maternal age at delivery and allergic rhinitis in schoolchildren: A population-based study.

World Allergy Organ J 2020 Jun 23;13(6):100127. Epub 2020 Jun 23.

Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan, Taiwan.

Background: Some studies have shown associations of maternal age at delivery with asthma and food allergy in offspring. However, the relationship between maternal age at delivery and allergic rhinitis is largely unclear. This study aimed to investigate the association between maternal age at delivery and allergic rhinitis in a population sample of Asian children, and to explore potential effect modifiers. Read More

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http://dx.doi.org/10.1016/j.waojou.2020.100127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322179PMC

Sublingual immunotherapy for food allergy and its future directions.

Immunotherapy 2020 Jul 2. Epub 2020 Jul 2.

Department of Medicine, Division of Rheumatology, Allergy & Immunology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA.

Food allergy is an important medical problem with increasing prevalence throughout the world. Different approaches of food immunotherapy are being investigated including oral, epicutaneous and sublingual routes. Sublingual immunotherapy (SLIT) for food allergy involves placement of glycerinated allergen under the tongue daily to achieve allergen-specific desensitization. Read More

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http://dx.doi.org/10.2217/imt-2020-0123DOI Listing

Treatment Options for Cow's Milk Protein Allergy: A Modeling Analysis.

Clinicoecon Outcomes Res 2020 17;12:307-315. Epub 2020 Jun 17.

Cukurova University Medical School, Allergy and Immunology Department, Adana, Turkey.

Purpose: Cow's milk protein allergy (CMPA) is one of the most common food allergies in early childhood. We aimed to evaluate clinical and economic outcomes of the amino-acid formula (AAF) and extensively hydrolyzed formula (eHF) based treatment of CMPA by using data available from Turkey and otherwise from literature.

Materials And Methods: A theoretical model was developed to evaluate AAF and eHF for CMPA treatment in terms of the number of children tolerating formula or experiencing an allergic reaction or withdrawing formula due to taste or other palatability features and CMPA related direct medical costs from the payer perspective. Read More

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http://dx.doi.org/10.2147/CEOR.S242021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306455PMC

[Relationship between gene polymorphism at rs2228055 locus in the exon region of interleukin-10 receptor A and susceptibility to food allergy in children].

Authors:
J B Sun Z L Li

Zhonghua Er Ke Za Zhi 2020 Jul;58(7):559-563

Department of Pediatrics, Peking University Third Hospital, Beijing 100191, China.

To investigate the relationship between gene polymorphism of rs2228055 locus in the exon region of interleukin-10 receptor A (IL-10RA) and susceptibility to food allergy in children. This was a case-control study. The food allergy group had 150 children who were diagnosed with food allergy in the Pediatric Food Allergy Clinic of Peking University Third Hospital from August 1, 2017 to November 30, 2018. Read More

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http://dx.doi.org/10.3760/cma.j.cn112140-20200425-00433DOI Listing

Occupational Airborne Contact Urticaria, Anaphylaxis and Asthma in Farmers and Agronomists Due to Bruchus Pisorum.

Contact Dermatitis 2020 Jun 26. Epub 2020 Jun 26.

Laboratorios DIATER. Madrid., Spain.

Background: Occupational contact urticaria due to inhalation of legume pest allergens has rarely been described.

Objective: To determine the cause of an outbreak of airborne contact urticaria, asthma and anaphylaxis in farmers and agronomists studying the disinsectization of dried peas. Peas were treated with aluminum phosphide (EPA). Read More

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http://dx.doi.org/10.1111/cod.13644DOI Listing

Natural products targeting FcεRI receptor for anti-allergic therapeutics.

Authors:
Thanh Sang Vo

J Food Biochem 2020 Jun 25:e13335. Epub 2020 Jun 25.

Faculty of Natural Sciences, Thu Dau Mot University, Thu Dau Mot City, Vietnam.

Mast cells and basophils are important contributors for development of allergic reactions. The activation of these cells via cross-linking of IgE bound to FcεRI by allergen causes the generation of allergic mediators and the reaction of immediate hypersensitivity. Obviously, FcεRI is considered as a key trigger of acute allergic responses. Read More

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http://dx.doi.org/10.1111/jfbc.13335DOI Listing

Does 3-pentadecylcatechol, an urushiol derivative, get absorbed in the body? A rat oral administration experiment.

Food Sci Biotechnol 2020 Jul 14;29(7):997-1005. Epub 2020 Mar 14.

Department of Food Science and Technology, Chonnam National University, 77 Yongbongro, Gwangju, 61186 Republic of Korea.

Urushiols are important active compounds found in the sap of the lacquer tree ( Stokes). Recently, various biological effects of urushiols, such as antioxidant, antimicrobial, and anticancer activities, have been reported. However, urushiols can also induce skin allergies. Read More

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http://dx.doi.org/10.1007/s10068-020-00739-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297941PMC

Sensitization to storage proteins in peanut and hazelnut is associated with higher levels of inflammatory markers in asthma.

Clin Mol Allergy 2020 23;18:11. Epub 2020 Jun 23.

Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

Background: Sensitization to peanuts and hazelnuts is common among young asthmatics and can be primary or a result of cross-reactivity. Sensitization as a result of cross-reactivity to birch pollen is typically associated to tolerance or mild and local symptoms upon intake of peanut or hazelnut.

Aim: The aim of this study was to investigate relationships between IgE antibody responses against peanut and hazelnut components, airway and systemic inflammation markers, lung function parameters and reported food hypersensitivity in a cohort of asthmatic children and young adults. Read More

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http://dx.doi.org/10.1186/s12948-020-00126-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7310284PMC

Global implementation of the world health organization's international classification of diseases (ICD)-11: the allergic and hypersensitivity conditions model.

Allergy 2020 Jun 23. Epub 2020 Jun 23.

University Hospital of Montpellier, Montpellier, France.

The International Classification of Diseases (ICD) provides a common language for use worldwide as a diagnostic and classification tool for epidemiology, clinical purposes and health management. Since its first edition, the ICD has maintained a framework distributing conditions according to topography, with the result that some complex conditions, such as allergies and hypersensitivity disorders (A/H) including anaphylaxis, have been poorly represented. The change in hierarchy in ICD-11 permitted the construction of the pioneer section addressed to A/H, which may result in more accurate mortality and morbidity statistics, including more accurate accounting for mortality due to anaphylaxis, strengthen classification, terminology and definitions. Read More

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http://dx.doi.org/10.1111/all.14468DOI Listing

Age-at-onset-dependent effects of sulfur amino acid restriction on markers of growth and stress in male F344 rats.

Aging Cell 2020 Jun 22. Epub 2020 Jun 22.

Animal Science Laboratory, Orentreich Foundation for the Advancement of Science, NY, USA.

Trade-offs in life-history traits are clinically and mechanistically important. Sulfur amino acid restriction (SAAR) extends lifespan. But whether this benefit comes at the cost of other traits including stress resistance and growth is unclear. Read More

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http://dx.doi.org/10.1111/acel.13177DOI Listing

Precision Lactobacillus reuteri therapy attenuates luminal distention-associated visceral hypersensitivity by inducing peripheral opioid receptors in the colon.

Pain 2020 Jun 19. Epub 2020 Jun 19.

Dept. of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA.

Luminal distention and abdominal pain are major clinical hallmarks of obstructive bowel disorders and functional bowel disorders linked to gut dysbiosis. Our recent studies found that chronic lumen distention increased visceral sensitivity and decreased abundance of gut commensal Lactobacillus reuteri in a rodent model of partial colon obstruction (OB). To establish causation, we performed precision microbial therapy to assess whether recolonization of L. Read More

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http://dx.doi.org/10.1097/j.pain.0000000000001967DOI Listing

A rare case of anaphylaxis to Indian jujube ().

Allergy Asthma Clin Immunol 2020 17;16:48. Epub 2020 Jun 17.

Division of Allergy & Immunology, Department of Medicine, Queen's University, Hotel Dieu Hospital, 166 Brock Street, Kingston, ON K7L 5G2 Canada.

Background: Indian jujube () is a sweet fruit from a tree native to tropical and subtropical regions of Asia and India. A few case reports have implicated Indian jujube to cause latex-fruit syndrome. We present the first case of an anaphylactic reaction to this fruit in a patient with no latex allergy. Read More

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http://dx.doi.org/10.1186/s13223-020-00444-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7302346PMC

Vulvar pain: The revealing scenario of leading comorbidities in 1183 cases.

Eur J Obstet Gynecol Reprod Biol 2020 May 30;252:50-55. Epub 2020 May 30.

ASP 7, Ragusa Hospital, Italy.

Objectives: This study set out to investigate the epidemiological characteristics and comorbidities of chronic vulvar pain. Secondary goals were to identify the preferred approaches for managing vulvodynia in Italy.

Study Design: A cross-sectional study (the VuNet -Vulvodynia Network project) was performed in consecutive female patients with chronic vulvar pain attending 21 Italian medical centers (public hospitals, university clinics and private outpatient services) in the period December 2016 to November 2018. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2020.05.052DOI Listing

Review of monoclonal antibody therapies in asthma and allergic diseases - a new paradigm for precision medicine.

Asian Pac J Allergy Immunol 2020 Jun;38(2):78-90

Faculty of Life Sciences & Medicine, School of Immunology & Microbial Sciences, Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, UK.

Background: Elucidation of the critical immune pathways involved in allergic inflammation has identified, apart from IgE, therapeutic targets in the cytokine network suitable for intervention by biological therapies.

Objective: The drugs that target the cytokine networks pertinent to asthma and allergic diseases are reviewed and some illustrative case histories presented. The overview proposes a framework to use when deciding which monoclonal antibody (mAb) to select for treatment of severe asthma based on total IgE concentration, peripheral blood eosinophil count, induced sputum analysis and measurement of fractional exhaled nitric oxide (FENO). Read More

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http://dx.doi.org/10.12932/AP-020220-0752DOI Listing

The influence of cultural attitudes to nut exposure on reported nut allergy: A pilot cross sectional study.

PLoS One 2020 19;15(6):e0234846. Epub 2020 Jun 19.

Faculty of Health Sciences and Wellbeing, University of Sunderland, Sunderland, United Kingdom.

Food allergies in children have become a common management and diagnostic concern and have a significant influence on general health-related quality of life. We investigated the prevalence of reported nut allergy between populations with different cultural attitudes to nuts during pregnancy and infancy. We conducted a survey to investigate the relationship between cultural differences in the consumption of nuts during pregnancy, breastfeeding and exposure to nuts in early childhood against the reported prevalence of nut allergy between three populations: Libyan, UK Libyan and a general UK population. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234846PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304617PMC

EAACI Guideline on the effective transition of adolescents and young adults with allergy and asthma.

Allergy 2020 Jun 19. Epub 2020 Jun 19.

Nederlands Anafylaxis Netwerk - European Anaphylaxis Taskforce, Dordrecht, The Netherlands.

Adolescent and young adult (AYA) patients need additional support while they experience the challenges associated with their age. They need specific training to learn the knowledge and skills required to confidently self-manage their allergies and/or asthma. Transitional care is a complex process which should address the psychological, medical, educational and vocational needs of AYA in the developmentally appropriate way. Read More

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http://dx.doi.org/10.1111/all.14459DOI Listing

Anaphylaxis.

Eur Ann Allergy Clin Immunol 2020 06 19. Epub 2020 Jun 19.

Allergy Unit, Department of Internal Medicine, University Hospital of Ancona, Ancona, Italy.

Anaphylaxis is the most severe systemic hypersensitivity reaction, and it can be life-threatening or even fatal. It involves the activation of multiple immune and non immune pathways beyond IgE, thus exhibiting different phenotypes. New symptoms of hypersensitivity caused by chemotherapy drugs, monoclonal antibodies, and biological agents have been suggested to be recognized as anaphylaxis phenotypes. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.158DOI Listing

Decreased Outpatient Fluoroquinolone Prescribing Using a Multimodal Antimicrobial Stewardship Initiative.

Open Forum Infect Dis 2020 Jun 21;7(6):ofaa182. Epub 2020 May 21.

Division of Infectious Diseases, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Background: Fluoroquinolones are antibiotics prescribed in the outpatient setting, though they have serious side effects. This study evaluates the impact of stewardship interventions on total and inappropriate prescribing of fluoroquinolones in outpatient settings in a large county hospital and health system.

Methods: In an effort to decrease inappropriate outpatient fluoroquinolone usage, a multimodal antimicrobial stewardship initiative was implemented in November 2016. Read More

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http://dx.doi.org/10.1093/ofid/ofaa182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284006PMC

Hypersensitivity reactions to biologics (part I): allergy as an important differential diagnosis in complex immune-derived adverse events.

Allergo J 2020 24;29(4):32-61. Epub 2020 Jun 24.

Klinische und Molekulare Allergologie - Forschungszentrum Borstel, Parkallee 35, 23845 Borstel, Germany.

Biotechnological substances (BSs) are strongly relied upon to prevent rejection of transplanted organs, and to treat oncological, allergological, and other inflammatory diseases. Allergic reactions to partly foreign biologics can occur due to their potential immunogenicity. The severity of an immune response to a biological drug may range from no clinical significance to a severe, life-threatening anaphylactic reaction. Read More

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http://dx.doi.org/10.1007/s15007-020-2550-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289641PMC

In "High-Risk" Infants with Sufficient Vitamin D Status at Birth, Infant Vitamin D Supplementation Had No Effect on Allergy Outcomes: A Randomized Controlled Trial.

Nutrients 2020 Jun 11;12(6). Epub 2020 Jun 11.

School of Medicine, The University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia.

Lower vitamin D status at birth and during infancy has been associated with increased incidence of eczema and food allergies. The aim of this study was to investigate the effect of early infancy vitamin D supplementation on allergic disease outcomes in infants at "hereditary risk" of allergic disease, but who had sufficient vitamin D levels at birth. Here, we report the early childhood follow-up to 2. Read More

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http://dx.doi.org/10.3390/nu12061747DOI Listing

Prevalence of IgE-mediated sensitization in patients with suspected food allergic reactions in Jordan.

Immun Inflamm Dis 2020 Jun 15. Epub 2020 Jun 15.

Biolab Diagnostic Laboratories, Amman, Jordan.

Background: Despite the recognition of food allergies as a significant cause of morbidity and a growing public health burden worldwide, there are no epidemiological studies addressing food sensitization and allergy in Jordan.

Objective: To conduct an epidemiological study that retrospectively analyzes sensitization data from 3463 patients with suspected immunoglobulin E (IgE)-mediated food allergic reactions who performed specific IgE tests in our laboratories in Jordan.

Methods: Specific IgE (s-IgE) tests were analyzed for patients who performed enzyme allegro-sorbent testing based on either self-reported food allergy or upon physician's request. Read More

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http://dx.doi.org/10.1002/iid3.320DOI Listing

Alpha-gal syndrome: an emerging cause of food and drug allergy.

Clin Exp Allergy 2020 Jun 15. Epub 2020 Jun 15.

Department of Infectious Diseases and Neuroinfections, Medical University of Bialystok, Bialystok, Poland.

Alpha-gal syndrome (AGS) describes a wide spectrum of hypersensitivity reactions mediated by specific IgE to the α-gal epitope (galactose-α-1,3- galactose) ubiquitously expressed on glycoproteins/glycolipids of most mammals. This fascinating new entity has completely changed the paradigms of allergy as allergic response is directed against an oligosaccharide and the reactions can be both immediate and delayed. They appear to be stimulated only by tick bites which induce production of α-gal specific IgE antibodies that lead to (at times fatal) hypersensitivity response. Read More

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http://dx.doi.org/10.1111/cea.13683DOI Listing

LC-HRMS/MS for the simultaneous determination of four allergens in fish and swine food products.

Food Chem 2020 Jun 8;331:127276. Epub 2020 Jun 8.

Istituto Zooprofilattico Sperimentale delle Venezie, Department of Chemistry, Legnaro PD, Italy.

The inclusion on the label of packed foods of any ingredient or technological adjuvant causing allergies is required by EU food legislation. In this study a targeted proteomics method for detecting four allergens in animal-derived food matrices was developed. Liquid chromatography coupled with high-resolution tandem mass spectrometry (LC-HRMS/MS) was used to select marker peptides from four allergens and develop a quantitative method able to simultaneously detect the presence of milk, egg, crustaceans and soy. Read More

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http://dx.doi.org/10.1016/j.foodchem.2020.127276DOI Listing

Insight into the Time Course of Type III Kounis Syndrome: A Case Report.

J Emerg Med 2020 Jun 11. Epub 2020 Jun 11.

Department of Cardiology, Matsushita Memorial Hospital, Osaka, Japan.

Background: Kounis syndrome is a rare condition that is characterized by the coexistence of acute coronary syndrome and allergic reactions; however, its time course remains unclear. We report a case of anaphylactic shock with subsequent development of ST-segment elevation myocardial infarction.

Case Report: A 47-year-old man with food allergies presented to the emergency department of our hospital with breathing difficulties after eating bread. Read More

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http://dx.doi.org/10.1016/j.jemermed.2020.04.054DOI Listing

Phenotyping peach-allergic patients sensitised to LTP and analysing severity biomarkers.

Allergy 2020 Jun 14. Epub 2020 Jun 14.

Allergy Unit, IBIMA- Hospital Regional Universitario de Malaga, Malaga, Spain.

Background: Patients with peach allergy due to nsLTP sensitisation constitute a heterogeneous group in terms of sensitisation profile and severity. This could be due to the presence of additional allergies to pollens. The aim of this study was to analyse the clinical characteristics, sensitisation profile, and severity of reactions in peach-allergic patients sensitised to nsLTP from two Mediterranean areas with different pollen exposure. Read More

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http://dx.doi.org/10.1111/all.14447DOI Listing

Low frequency of IgE-mediated food hypersensitivity in mastocytosis.

J Allergy Clin Immunol Pract 2020 Jun 10. Epub 2020 Jun 10.

Department of Respiratory Medicine and Allergy, Karolinska University Hospital Huddinge, Stockholm, Sweden;; Clinical Immunology and Allergy Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden;; Mastocytosis Center Karolinska, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden;. Electronic address:

Background: Patients with mastocytosis have an increased risk for severe anaphylaxis, particularly to hymenoptera venoms. These patients may also develop more often systemic hypersensitivity reactions to certain foods. However, this issue has not been systematically investigated. Read More

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http://dx.doi.org/10.1016/j.jaip.2020.05.044DOI Listing

COVID-19 pandemic: Practical considerations on the organization of an allergy clinic - an EAACI/ARIA Position Paper.

Allergy 2020 Jun 12. Epub 2020 Jun 12.

Transylvania University, Brasov, Romania.

Background: The Coronavirus disease 2019 (COVID-19) has evolved as a pandemic infectious disease transmitted by the severe acute respiratory syndrome coronavirus (SARS-CoV-)2. Allergists and other health care providers (HCPs) in the field of allergies and associated airway diseases are in the front line, taking care of patients potentially infected with SARS-CoV-2. Hence, strategies and practices to minimize risks of infection for both HCPs and treated patients have to be developed and followed by allergy clinics. Read More

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http://dx.doi.org/10.1111/all.14453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323448PMC

Dietary factors during pregnancy and atopic outcomes in childhood: a systematic review from the European Academy of Allergy and Clinical Immunology.

Pediatr Allergy Immunol 2020 Jun 10. Epub 2020 Jun 10.

Depts of Medicine and Microbiology, APC Microbiome Ireland, National University of Ireland, Cork, Ireland.

Rationale: Allergic diseases are an increasing public health concern and early life environment is critical to immune development. Maternal diet during pregnancy has been linked to offspring allergy risk. In turn, maternal diet is a potentially modifiable factor, which could be targeted as an allergy prevention strategy. Read More

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http://dx.doi.org/10.1111/pai.13303DOI Listing

ABC1K10a, an atypical kinase, functions in plant salt stress tolerance.

BMC Plant Biol 2020 Jun 10;20(1):270. Epub 2020 Jun 10.

State Key Laboratory of Crop Stress Adaptation and Improvement, School of Life Sciences, Henan University, Kaifeng, China.

Background: ABC1K (Activity of BC1 complex Kinase) is an evolutionarily primitive atypical kinase family widely distributed among prokaryotes and eukaryotes. The ABC1K protein kinases in Arabidopsis are predicted to localize either to the mitochondria or chloroplasts, in which plastid-located ABC1K proteins are involved in the response against photo-oxidative stress and cadmium-induced oxidative stress.

Results: Here, we report that the mitochondria-localized ABC1K10a functions in plant salt stress tolerance by regulating reactive oxygen species (ROS). Read More

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http://dx.doi.org/10.1186/s12870-020-02467-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7288548PMC

Milk-free diet followed by breastfeeding women.

Rocz Panstw Zakl Hig 2020 ;71(2):181-189

Warsaw University of Life Sciences - SGGW, Institute of Human Nutrition Sciences. Department of Dietetics, Warsaw, Poland.

Background: Breastfeeding is the most common way of feeding infants. Human milk contains nutrients which are necessary to provide proper growth of a child. Nowadays there aren't any recommendations to follow elimination diet in order to decrease the risk of allergy or baby colic. Read More

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http://dx.doi.org/10.32394/rpzh.2020.0118DOI Listing
January 2020

Black Raspberries and Protocatechuic Acid Mitigate DNFB-Induced Contact Hypersensitivity by Down-Regulating Dendritic Cell Activation and Inhibiting Mediators of Effector Responses.

Nutrients 2020 Jun 6;12(6). Epub 2020 Jun 6.

Department of Pathology, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA.

Contact hypersensitivity (CHS) is the most common occupational dermatological disease. Dendritic cells (DCs) mediate the sensitization stage of CHS, while T-cells facilitate the effector mechanisms that drive CHS. Black raspberry (, BRB) and BRB phytochemicals possess immunomodulatory properties, but their dietary effects on CHS are unknown. Read More

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http://dx.doi.org/10.3390/nu12061701DOI Listing

Food allergy? Intolerance? – Examination of adverse reactions to foods in 406 adult patients

Orv Hetil 2020 06;161(25):1042-1049

Általános Orvostudományi Kar, Bőr-, Nemikórtani és Bőronkológiai Klinika,Semmelweis Egyetem Budapest.

Introduction: The prevalence of adverse food reactions is increasing, with 10-20% of the adult population experiencing such complaints. Most symptoms are thought to be indicators of food allergy, although non-immune-mediated food intolerance and other (e.g. Read More

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http://dx.doi.org/10.1556/650.2020.31753DOI Listing

Production of allergen-specific immunotherapeutic agents for the treatment of food allergy.

Crit Rev Biotechnol 2020 Jun 9:1-14. Epub 2020 Jun 9.

National Food Institute, Technical University of Denmark, Kgs. Lyngby, Denmark.

Allergen-specific immunotherapy (IT) is emerging as a viable avenue for the treatment of food allergies. Clinical trials currently investigate raw or slightly processed foods as therapeutic agents, as trials using food-grade agents can be performed without the strict regulations to which conventional drugs are subjected. However, this limits the ability of standardization and may affect clinical trial outcomes and reproducibility. Read More

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http://dx.doi.org/10.1080/07388551.2020.1772194DOI Listing

Food Allergy Management at School in the Era of Immunotherapy.

Curr Allergy Asthma Rep 2020 Jun 6;20(8):32. Epub 2020 Jun 6.

Department of Pediatrics, Division of Allergy and Immunology, National Jewish Health, Denver, CO, 80206, USA.

Purpose Of Review: Food allergy is increasing in prevalence, and management focuses on strict avoidance of known allergens and appropriately treating reactions. Any reaction has the potential to result in anaphylaxis, which can be fatal. Children spend a significant amount of time in the childcare or school setting, and interactions between families, school personnel, and clinicians are important to ensure the health and safety of children with allergies and asthma. Read More

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http://dx.doi.org/10.1007/s11882-020-00933-5DOI Listing

Consensus Report from the Food Allergy Research and Education (FARE) 2019 Oral Immunotherapy for Food Allergy Summit.

J Allergy Clin Immunol 2020 Jun 4. Epub 2020 Jun 4.

Chief Medical Advisor, Food Allergy Research and Education (FARE), Professor of Medicine and Pediatrics, University of South Florida, Tampa, Florida, USA. Electronic address:

Food allergy is a major health problem affecting 5 to 10% of the population in developed nations, including an estimated 32 million Americans. Despite the large number of patients suffering from food allergies, up until the end of January 2020, no treatment for food allergies had been approved by the U.S. Read More

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http://dx.doi.org/10.1016/j.jaci.2020.05.027DOI Listing

Sublingual Omp16-driven redirection of the allergic intestinal response in a pre-clinical model of food allergy.

Clin Exp Allergy 2020 Jun 5. Epub 2020 Jun 5.

Instituto de Estudios Inmunológicos y Fisiopatológicos (IIFP), UNLP, CONICET, asociado a CIC PBA, Facultad de Ciencias Exactas, Departamento de Ciencias Biológicas, La Plata, Argentina.

Background: IgE-mediated food allergy remains a significant and growing worldwide problem. Sublingual immunotherapy (SLIT) shows an excellent safety profile for food allergy, but the clinical efficacy needs to be improved. This study assessed the effects of the Toll-like receptor 4 agonist outer membrane protein (Omp) 16 from Brucella abortus combined with cow´s milk proteins (CMP) through the sublingual route to modulate cow's milk allergy in an experimental model. Read More

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http://dx.doi.org/10.1111/cea.13676DOI Listing

Sialylation of immunoglobulin E is a determinant of allergic pathogenicity.

Nature 2020 06 20;582(7811):265-270. Epub 2020 May 20.

Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Approximately one-third of the world's population suffers from allergies. Exposure to allergens crosslinks immunoglobulin E (IgE) antibodies that are bound to mast cells and basophils, triggering the release of inflammatory mediators, including histamine. Although IgE is absolutely required for allergies, it is not understood why total and allergen-specific IgE concentrations do not reproducibly correlate with allergic disease. Read More

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http://dx.doi.org/10.1038/s41586-020-2311-zDOI Listing

Tiered approach for the identification of Mal d 1 reduced, well tolerated apple genotypes.

Sci Rep 2020 Jun 4;10(1):9144. Epub 2020 Jun 4.

Biotechnology of Natural Products, Technical University Munich, Liesel-Beckmann-Str. 1, 85354, Freising, Germany.

A rising proportion of the world population suffers from food-related allergies, including incompatibilities to apples. Although several allergenic proteins have been found in apples, the most important proteins that cause allergic reactions to apples in Central-Northern Europe, and North America are the Mal d 1 proteins, which are homologues of the birch pollen allergen Bet v 1. As the demand for hypoallergenic fruits is constantly increasing, we selected apple genotypes with a low total content of Mal d 1 by enzyme-linked immunosorbent assay analysis from segregating populations and tested the tolerability of these fruits through a human provocation study. Read More

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http://dx.doi.org/10.1038/s41598-020-66051-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272412PMC

Fill rates and access to self-injectable epinephrine prescribed in a pediatric emergency department.

Am J Emerg Med 2020 Apr 26. Epub 2020 Apr 26.

Department of Pediatrics, Division of Pediatric Emergency Medicine, Children's Hospital at Montefiore/Albert Einstein College of Medicine, Bronx, NY, USA.

Background: Despite its life-saving potential in anaphylaxis, self-injectable epinephrine (SIE) is frequently not administered by caregivers prior to arrival in the emergency department (ED). Prescriptions from the ED often go unfilled which may contribute to the failure to receive SIE when needed.

Objective: To determine the prescription filling rate and accessibility of SIE devices among families discharged from the Pediatric ED with an SIE prescription. Read More

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http://dx.doi.org/10.1016/j.ajem.2020.04.070DOI Listing

Food Allergy from Infancy Through Adulthood.

J Allergy Clin Immunol Pract 2020 Jun;8(6):1854-1864

Sean N. Parker Center for Allergy and Asthma Research, Stanford University School of Medicine, Stanford, Calif.

Food allergies are the result of immune responses that cause adverse reactions to foods. Immune responses to foods may produce a spectrum of symptoms and disorders, including acute allergic reactions and anaphylaxis, food protein-induced allergic proctocolitis, food protein-induced enterocolitis syndrome, food-dependent, exercise-induced anaphylaxis, and oral allergy syndrome (pollen-food allergy syndrome). Food-allergic responses also contribute to chronic inflammatory disorders such as eosinophilic esophagitis and atopic dermatitis. Read More

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http://dx.doi.org/10.1016/j.jaip.2020.02.010DOI Listing

Prenatal exposure to endocrine disrupting chemicals and asthma and allergic diseases.

Authors:
M Casas M Gascon

J Investig Allergol Clin Immunol 2020 Jun 3. Epub 2020 Jun 3.

ISGlobal, Barcelona, Spain.

Endocrine-disrupting chemicals (EDCs), chemicals that can interfere with endogenous hormones and that are present in many consumer products, can affect the development and functions of the immune system. The prenatal period is critical because exposure to EDCs can induce irreversible changes in the immune system and increase the susceptibility of asthma and allergies later in life. Non-persistent EDCs are of most concern due to their high annual production and potential toxicity. Read More

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http://dx.doi.org/10.18176/jiaci.0580DOI Listing

Quail´s egg anaphylaxis with tolerance to hen´s egg: a work-related case.

J Investig Allergol Clin Immunol 2020 Jun 3. Epub 2020 Jun 3.

Allergy and Clinical Immunology Department, Centro Hospitalar Vila Nova de Gaia/Espinho, EPE, Vila Nova de Gaia, Portugal.

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http://dx.doi.org/10.18176/jiaci.0507DOI Listing

Development of ELISA and chemiluminescence enzyme immunoassay for quantification of histamine in drug products and food samples.

Anal Bioanal Chem 2020 Jul 1;412(19):4739-4747. Epub 2020 Jun 1.

College of Biological Science and Engineering, Shaanxi University of Technology, East on the 1st Ring Road, Hanzhong, 723000, Shaanxi, China.

Histamine (HA) is a biogenic amine associated with allergies and food poisoning. It is an important indicator of food freshness and quality. In recent years, a series of medical negligence cases have been reported to be related to the intravenous injection of antibiotics produced via fermentation with fish peptone due to HA contamination. Read More

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http://dx.doi.org/10.1007/s00216-020-02730-5DOI Listing

Preliminary ICF core set for patients with myalgic encephalomyelitis/chronic fatigue syndrome in rehabilitation medicine.

J Rehabil Med 2020 Jun 30;52(6):jrm00074. Epub 2020 Jun 30.

Department of Clinical Sciences, Karolinska Institutet, Danderyd University Hospital, Building 39, 3rd Floor, SE-182 88 Stockholm, Sweden. E-mail:

Objective: To create and evaluate a preliminary ICF Core Set for myalgic encephalomyelitis/chronic fatigue syndrome using a team-based approach.

Design: Observational study.

Subjects/patients: A total of 100 consecutive patients (mean age 45 years (standard deviation (SD) 9 years)) were assessed by a rehabilitation team and included in the study. Read More

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http://dx.doi.org/10.2340/16501977-2697DOI Listing

Improving Allergy Documentation: A Retrospective Electronic Health Record System-Wide Patient Safety Initiative.

J Patient Saf 2020 Jun 1. Epub 2020 Jun 1.

From the Division of Allergy and Clinical Immunology, Department of Medicine, Brigham and Women's Hospital.

Objectives: Documentation of allergies in a coded, non-free-text format in the electronic health record (EHR) triggers clinical decision support to prevent adverse events. Health system-wide patient safety initiatives to improve EHR allergy documentation by specifically decreasing free-text allergy entries have not been reported. The goal of this initiative was to systematically reduce free-text allergen entries in the EHR allergy module. Read More

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http://dx.doi.org/10.1097/PTS.0000000000000711DOI Listing

Food sensitization in preschool Egyptian children with recurrent wheezing.

Pediatr Res 2020 Jun 2. Epub 2020 Jun 2.

Clinical Pathology Department, Faculty of Medicine, Assiut University, 71526, Assiut, Egypt.

Background: Food allergy is common in children with prevalence up to 10%. We assessed the clinico-laboratory characteristics and frequency of food sensitization to the commonly consumed food among upper Egyptian preschool children with recurrent wheezy chest.

Methods: This cross-sectional descriptive study was conducted on 100 preschool children with recurrent wheezy chest recruited from Emergency, Allergy, and Pulmonology units, Assiut University Children's Hospital, Egypt. Read More

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http://dx.doi.org/10.1038/s41390-020-0960-0DOI Listing