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    Classic form of eosinophilic pustular folliculitis in an immunocompetent girl: rapid and complete resolution after low-dose oral indomethacin treatment.
    Dermatol Online J 2017 Nov 15;23(11). Epub 2017 Nov 15.
    Department of Dermatology, School of Medicine, University of Patras, Rio-Patras, Greece, Center for Dermatologic Diseases, Limassol, Cyprus.
    Eosinophilic pustular folliculitis (EPF) is a rare noninfectious pruritic dermatosis, first described by Ise and Ofuji in 1965. We report the case of a 15-year oldimmunocompetent girl that presented with a widespread papulopustular eruption four days after her arrival in Japan. The clinical diagnosis of the classicform of EPF was confirmed by histological examination of the lesional skin that revealed an intense, mainly eosinophilic, dermal infiltrate within and aroundpilosebaceous units. Read More

    A case of atypical eosinophilic pustular folliculitis that emerged following the administration of capecitabine.
    J Eur Acad Dermatol Venereol 2018 Feb 14. Epub 2018 Feb 14.
    Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Shogoin Kawahara-cho, Sakyo, 606-8507, Kyoto, Japan.
    A 66-year-old man presented with aggregated pruritic follicular papulopustules on the forearms and thighs (Figure A). Each papulopustule was 1 mm in size, and arose from the hair follicle area (Figure B). The patient had undergone laparoscopic colectomy one month prior, and had been given a course of chemotherapy with capecitabine at 4,200 mg per day orally for 14 days followed by a 7-day washout period. Read More

    Mucocutaneous Manifestations in Patients with Chronic Kidney Disease: A Cross-sectional Study.
    Indian Dermatol Online J 2018 Jan-Feb;9(1):20-26
    Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Kangra, Himachal Pradesh, India.
    Background: Chronic kidney disease (CKD)-associated mucocutaneous manifestations significantly impair the quality of life but often remain understudied. They may also vary across regions, socioeconomic and nutritional status, and racial differences.

    Objectives: To study the patterns of mucocutaneous disorders and their prevalence in CKD patients irrespective of clinical stage or dialysis status. Read More

    Eruptive Vellus Hair Cyst: An Uncommon and Underdiagnosed Entity.
    Int J Trichology 2018 Jan-Feb;10(1):31-33
    Department of Dermatology, Hindu Rao Hospital and NDMC Medical College, NewDelhi, India.
    Eruptive vellus hair cyst (EVHC) is a rare follicular developmental abnormality of the vellus hair follicles. They are usually seen in children, adolescents, or young adults and manifest as reddish-brown smooth papules most commonly involving the chest, limbs, and abdomen. An 18-year-old male presented with asymptomatic papules on the trunk and flexor aspect of both forearms for the past 2 years. Read More

    [Postmenopausal lichen planopilaris also known as fibrosing frontotemporal alopecia Kossard : An evidence-oriented practical guide to treatment from the University of the Saarland, Hair Research Center of the Dr. Rolf M. Schwiete Foundation].
    Hautarzt 2018 Feb;69(2):134-142
    Klinik für Dermatologie, Venerologie und Allergologie, Universität des Saarlandes, Campus Homburg, Homburg, Deutschland.
    Postmenopausal lichen planopilaris (PLPP), also known as fibrosing frontotemporal alopecia Kossard (FFAK), is a not uncommon inflammatory scalp disease affecting approximately 5% of patients at specialized hair centers. The overall incidence of sporadic occurrence is believed to be just under 1% in the older, predominantly female, general population. Since the disease is often undiagnosed, it is statistically likely to be underrepresented. Read More

    Primary scarring alopecia: A retrospective study of 89 patients in Taiwan.
    J Dermatol 2018 Jan 16. Epub 2018 Jan 16.
    Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
    Primary scarring alopecia (PSA) is caused by irreversible damage to the hair epithelial stem cells that reside in hair follicles. There is limited published work regarding PSA amongst the Asian population. The aim of this study was to evaluate the clinical features and to characterize the subtypes of PSA in southern Taiwan. Read More

    Isotretinoin treatment for folliculitis decalvans: a retrospective case-series study.
    Int J Dermatol 2018 Feb 4;57(2):250-253. Epub 2018 Jan 4.
    Faculty of Medicine, Department of Dermatology, Celal Bayar University, Manisa, Turkey.
    Background: The literature includes only a few reports of oral isotretinoin for the treatment of folliculitis decalvans (FD). This study aimed to determine the most effective dose and duration of oral isotretinoin monotherapy for achieving remission in FD patients.

    Methods: This retrospective case series study included FD patients that were treated with oral isotretinoin. Read More

    Medical Adhesive-Related Skin Injury Prevalence at the Peripherally Inserted Central Catheter Insertion Site: A Cross-sectional, Multiple-Center Study.
    J Wound Ostomy Continence Nurs 2018 Jan/Feb;45(1):22-25
    Huihan Zhao, BSN, RN, Department of Nursing, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. Yu He, MD, Department of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. Qin Wei, MN, RN, Department of Nursing, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China. Yanping Ying, MN, RN, Department of Nursing, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
    Purpose: We examined prevalence and associated risk factors of medical adhesive-related skin injury (MARSI) at the peripherally inserted central catheter (PICC) insertion site in hospitalized oncology patients in Guangxi, China.

    Design: A cross-sectional, multiple-center epidemiological study.

    Subjects And Setting: The sample comprised 697 adult inpatients at 4 tertiary hospitals (3 general hospitals and 1 oncology hospital). Read More

    Naked Hair Shafts as a Marker of Cicatricial Alopecia.
    Am J Dermatopathol 2017 Dec 28. Epub 2017 Dec 28.
    Departments of Dermatology, and.
    Naked hair shafts (NHS) are free-floating hair shafts devoid of surrounding epithelium, supporting structures, and/or embedded in inflammation that may result from destruction of hair follicles by scarring processes such as inflammation and fibroplasia. Extensive examination of NHS has not been performed in scalp biopsies of alopecia. We retrospectively evaluated 622 scalp biopsies of alopecia [345 cicatricial alopecias (central centrifugal cicatricial alopecia, lichen planopilaris, discoid lupus erythematosus, acne keloidalis nuchae, and folliculitis decalvans] and 277 non-cicatricial alopecias [alopecia areata, androgenic alopecia, telogen effluvium, and psoriatic alopecia)] for the presence of NHS. Read More

    [A case of chronic progressive neuro-Behçet disease with extensive cerebral atrophy and elevated CSF IL-6 activity treated with infliximab].
    Rinsho Shinkeigaku 2018 Jan 22;58(1):30-34. Epub 2017 Dec 22.
    Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences.
    A 43-year-old man without a previous episode of uveitis presented with slowly progressive neurological symptoms that appeared within the past year such as dysarthria, ataxic gait, and behavioral changes. Brain MRI findings showed atrophic lesions in the brainstem and cerebellum. Because these clinical symptoms and abnormal MRI findings indicated spinocerebellar degeneration as the initial diagnosis, he was admitted to our hospital. Read More

    Red nodule on the face with "spontaneous" regression.
    An Bras Dermatol 2017 ;92(5 Suppl 1):135-137
    Department of Pathology. Hospital Universitario Doctor Peset. Valencia. Spain.
    Pseudolymphomatous folliculitis is a rare entity included among the cutaneous pseudolymphomas. A 32-year-old man, with an unremarkable medical history, presented with a two-month history of an asymptomatic solitary nodule on his left cheek. Histopathological examination demonstrated a dense nodular and diffuse dermal lymphocytic infiltrate with numerous histiocytes and dendritic cells that surrounded hypertrophic hair follicles. Read More

    Acne keloidalis nuchae in Asian: A single institutional experience.
    PLoS One 2017 14;12(12):e0189790. Epub 2017 Dec 14.
    Department of Pathology, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
    Acne keloidalis nuchae, a type of folliculitis involving the back of the neck, is common in black men, although rare cases have been reported in patients of other ethnicities. We analyzed the clinicopathological features of acne keloidalis nuchae in 17 Asians. Patients' age at the time of presentation ranged from 20 to 69 years. Read More

    Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid.
    BMC Vet Res 2017 Nov 21;13(1):345. Epub 2017 Nov 21.
    Research Centre for Topical Drug Delivery and Toxicology, Department of Pharmacy, Pharmacology & Postgraduate Medicine, University of Hertfordshire, Hatfield, UK.
    Background: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice. Topical therapy with fusidic acid (FA) is an attractive alternative to systemic therapy based on low minimum inhibitory concentrations (MICs, commonly <0.03 mg/l) documented in canine pathogenic staphylococci, including strains of MRSA and MRSP (methicillin-resistant Staphylococcus aureus and S. Read More

    Prevalence of medical adhesive-related skin injury at peripherally inserted central catheter insertion site in oncology patients.
    J Vasc Access 2017 Nov 8. Epub 2017 Nov 8.
    Department of Nursing, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi - China.
    Introduction: The aim of our study was to identify the prevalence and risk factors of medical adhesive-related skin injuries (MARSI) at peripherally inserted central catheters (PICC) insertion site in oncology patients.

    Methods: A cross-sectional observational study lasting two weeks was carried out in four inpatient departments. Skin assessment data and photographs of skin were collected during PICC maintenance. Read More

    Efficacy and Tolerability of a Twice-Daily, Three-Step Men's Skincare Regimen in Improving Overall Skin Quality and Reducing Shave-Related Irritation.
    Skinmed 2017 1;15(5):349-355. Epub 2017 Oct 1.
    Rodan + Fields, San Francisco, CA;
    More men are beginning to take advantage of opportunities to improve the health and appearance of their skin; however, the effectiveness of men's skincare regimens has not been well studied. The authors investigated the efficacy and tolerance of a twice-daily, three-step men's skincare regimen in improving skin appearance and reducing shave-related issues. Twenty-nine men who used a wet-shaving method completed a specific, three-step, twice-daily facial regimen-a Shave Cleanser, a Post-Shave Treatment, and Day Protection-in place of their usual routine for 4 weeks. Read More

    Pityrosporum folliculitis: A retrospective review of 110 cases.
    J Am Acad Dermatol 2018 Mar 11;78(3):511-514. Epub 2017 Nov 11.
    Department of Dermatology, University of Massachusetts Medical School, Worcester, Massachusetts.
    Background: Pityrosporum folliculitis is an under-recognized eruption of the face and upper portion of the trunk that may be confused with, or occur simultaneously with, acne vulgaris.

    Objective: We sought to characterize risk factors for Pityrosporum folliculitis, its clinical presentation, and its response to treatment.

    Methods: A retrospective chart review was performed on all patients age 0 to 21 years seen at our facility from 2010 to 2015 with Pityrosporum folliculitis confirmed by a potassium hydroxide preparation. Read More

    Utility of Gram staining for diagnosis of Malassezia folliculitis.
    J Dermatol 2018 Feb 13;45(2):228-231. Epub 2017 Nov 13.
    Department of Dermatology, Taipei Medical University Shuang Ho Hospital, New Taipei City, Taiwan.
    Malassezia folliculitis (MalF) mimics acne vulgaris and bacterial folliculitis in clinical presentations. The role of Gram staining in rapid diagnosis of MalF has not been well studied. In our study, 32 patients were included to investigate the utility of Gram staining for MalF diagnosis. Read More

    Erosive Pustular Dermatosis of the Scalp with Urate-Like Crystals.
    Case Rep Dermatol Med 2017 8;2017:1536434. Epub 2017 Oct 8.
    Auckland University of Technology, Auckland 1142, New Zealand.
    Follicular urate-like crystals were first described in Necrotizing Infundibular Crystalline Folliculitis (NICF), a rare cutaneous disorder with multiple waxy folliculocentric papules. Similar crystal accumulation may be seen within follicular infundibulae as an incidental finding. We describe a case showing identical crystals occurring within the horn-like crusts of a patient with erosive pustular dermatosis of the scalp (EPDS), a condition which due to its presentation can often be mistaken for nonmelanoma skin cancer. Read More

    [Pityriasis amiantacea and folliculitis decalvans : An unusual manifestation associated with antitumor necrosis factor-α therapy].
    Hautarzt 2017 Dec;68(12):1007-1010
    Universitätsklinik für Dermatologie und Venerologie, Medizinische Universität Innsbruck, Anichstr. 35, 6020, Innsbruck, Österreich.
    We report on a 21-year-old woman with a 3-year history of crusts and erosions on her scalp that had appeared after starting treatment with adalimumab due to Crohn's disease. By clinicopathological correlation pityriasis amiantacea with underlying folliculitis decalvans was diagnosed. Topical and systemic antibiotic treatment showed rapid response. Read More

    Autoimmune Progesterone Dermatitis: A Diagnosis to Consider in a Patient With Cyclical Cutaneous Eruptions.
    J Drugs Dermatol 2017 Oct;16(10):1040-1042
    Autoimmune progesterone dermatitis (APD) is a cyclical cutaneous reaction to progesterone, with symptoms that typically begin 3-10 days before the onset of menstrual flow and end 1-2 days into menses. The symptoms vary in severity from barely visible to anaphylaxis, but most often include an eczematous eruption, erythema multiforme, urticaria, folliculitis, and angioedema. This is a rare disorder with only a handful of documented cases. Read More

    Traction alopecia: A neglected entity in 2017.
    Indian J Dermatol Venereol Leprol 2017 Nov-Dec;83(6):644-649
    Department of Dermatology, School of Medicine, Cardiff University, Cardiff, CF, UK.
    Traction alopecia was first described in 1904 but is still a cause of scarring hair loss in young women worldwide. It is unique in being initially a reversible then an irreversible (scarring) form of alopecia. Linked to tightly-pulled hairstyles, it is seen across all races. Read More

    Certolizumab Pegol-Induced Folliculitis-Like Lichenoid Sarcoidosis in a Patient with Rheumatoid Arthritis.
    Case Rep Dermatol 2017 Sep-Dec;9(3):158-163. Epub 2017 Sep 11.
    Department of Dermatology, Asahikawa City Hospital, Asahikawa, Japan.
    Anti-tumor necrosis factor α (TNF-α) biologic agents are used for treating refractory sarcoidosis. However, sarcoidosis-like epithelioid cell granulomas may develop during anti-TNF-α treatment. A 63-year-old man suffering from rheumatoid arthritis was treated with oral methotrexate and methylprednisolone for 4 years. Read More

    An unresponsive progressive pustular and crusting dermatitis with acantholysis in nine cats.
    Vet Dermatol 2018 Feb 6;29(1):81-e33. Epub 2017 Oct 6.
    Department of Veterinary Medicine and Epidemiology, School of Veterinary Medicine, University of California, One Shields Avenue, Davis, CA, 95616, USA.
    Background: Between 2000 and 2012, nine cats were examined with a visually distinctive, progressive crusting dermatitis that was poorly responsive to all attempted therapies.

    Objectives: Documentation of clinical and histopathological findings of this disease.

    Animals: Nine privately owned cats. Read More

    Overexpression of NLRP3, NLRC4 and AIM2 inflammasomes and their priming-associated molecules (TLR2, TLR4, Dectin-1, Dectin-2 and NFκB) in Malassezia folliculitis.
    Mycoses 2018 Feb 13;61(2):111-118. Epub 2017 Oct 13.
    Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
    The activation of NLRP3, NLRC4 and AIM2 inflammasomes is pivotal for innate immunity against some pathogenic fungi, but their role in the pathogenesis of Malassezia folliculitis (MF) remains unclear. The objective of the study was to determine the expression of 4 canonical inflammasomes (NLRP1, NLRP3, NLRC4 and AIM2) and their priming-associated molecules (TLR2, TLR4, Dectin-1, Dectin-2 and NFκB) in MF lesion. Expression of NLRP1, NLRP3, NLRC4, AIM2, caspase-1, IL-1β, TLR2, TLR4, Dectin-1, Dectin-2 and NFκB was detected by immunohistochemistry in skin lesion of 23 MF patients and normal skin of 12 healthy subjects. Read More

    Lipid Metabolic Versatility inspp. Yeasts Studied through Metabolic Modeling.
    Front Microbiol 2017 14;8:1772. Epub 2017 Sep 14.
    Department of Biological Sciences, Universidad de los AndesBogotá, Colombia.
    species are lipophilic and lipid-dependent yeasts belonging to the human and animal microbiota. Typically, they are isolated from regions rich in sebaceous glands. They have been associated with dermatological diseases such as seborrheic dermatitis, pityriasis versicolor, atopic dermatitis, and folliculitis. Read More

    Systemic photodynamic therapy in folliculitis decalvans.
    Clin Exp Dermatol 2018 Jan 22;43(1):46-49. Epub 2017 Sep 22.
    Department of Clinical Oncology, The Christie NHS Foundation Trust and University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
    Folliculitis decalvans (FD) is classified as a primary neutrophilic cicatricial alopecia, and is estimated to account for approximately 10% of all cases of primary cicatricial alopecia. The role of dysfunctional immune activity and the presence of bacteria, particularly Staphylococcus aureus, appear pivotal. We describe a 26-year-old man with a 4-year history of FD that was recalcitrant to numerous systemic and topical therapies, whose disease was virtually cleared during a follow-up of 25 months following a course of treatment with systemic photodynamic therapy (PDT) using ultraviolet light (100-140 J/cm) with porfimer sodium 1 mg/kg as monotherapy. Read More


    [Acute skin infections and their imitators in children : A photo quiz].
    Hautarzt 2017 Oct;68(10):774-783
    Abteilung pädiatrische Dermatologie, Universitäts-Kinderspital Zürich, Steinwiesstrasse 75, 8032, Zürich, Schweiz.
    Background: Skin infections account for 40% of emergency visits in pediatric dermatology. It is important to promptly recognize skin infections with potential complications and initiate treatment. However some characteristic skin findings may imitate skin infections and are often misdiagnosed. Read More

    Disseminate recurrent folliculitis as the presenting picture of hidradenitis suppurativa.
    Ann Dermatol Venereol 2017 Nov 31;144(11):715-718. Epub 2017 Aug 31.
    11, chaussée de la Muette, 75016 Paris, France. Electronic address:
    Background: Hidradenitis suppurativa (HS) has a polymorphous clinical presentation. Herein we report two cases of HS revealed by disseminate recurrent folliculitis. PATIENTS AND METHODS CASE 1: A 31-year-old woman consulted for disseminate recurrent folliculitis on the trunk and proximal segments of the limbs that had been ongoing for several years. Read More

    Necrotizing Infundibular Crystalline Folliculitis: An Unusual Clinical Presentation and Demonstration of the Presence of Calcium Palmitate.
    Am J Dermatopathol 2018 Jan;40(1):e9-e11
    Department of Pathology, Necker-Enfants Malades Hospital, APHP, Paris, France.
    Necrotizing infundibular crystalline folliculitis (NICF) is a rare disorder, which was described for the first time by Lucke et al in 1999. NICF is characterized by multiple folliculocentric papules with a predilection for occurring in seborrheic areas in adults and corresponding dilated follicular ostia containing crystalline material. The precise pathogenesis and nature of this crystalline material are currently unknown. Read More

    Impact of Type III Secretion Effectors and of Phenoxyacetamide Inhibitors of Type III Secretion on Abscess Formation in a Mouse Model of Pseudomonas aeruginosa Infection.
    Antimicrob Agents Chemother 2017 Nov 24;61(11). Epub 2017 Oct 24.
    Department of Microbiology/Immunology, Northwestern University, Chicago, Illinois, USA
    is a leading cause of intra-abdominal infections, wound infections, and community-acquired folliculitis, each of which may involve macro- or microabscess formation. The rising incidence of multidrug resistance amongisolates has increased both the economic burden and the morbidity and mortality associated withdisease and necessitates a search for novel therapeutics. Previous work from our group detailed novel phenoxyacetamide inhibitors that block type III secretion and injection into host cellsIn this study, we used a mouse model ofabscess formation to test theefficacy of these compounds against thetype III secretion system (T3SS). Read More

    Marked improvement in gastric involvement in Behçet's disease with adalimumab treatment.
    Turk J Gastroenterol 2017 Sep 9;28(5):405-407. Epub 2017 Aug 9.
    Department of Gastroenterology, Oita University, Yufu, Japan.
    Gastric involvement is the least frequent manifestation of Behçet's disease, and effective treatment for it unknown. Here the case of a patient with gastric involvement in Behçet's disease that was markedly improved with adalimumab therapy is presented. A 68-year-old man developed an oral ulcer, erythema, folliculitis, and arthralgia. Read More

    [Pseudomonas aeruginosa in dermatology].
    Ann Dermatol Venereol 2017 Nov 2;144(11):666-675. Epub 2017 Aug 2.
    Service de dermatologie, hôpital d'instruction des armées Sainte-Anne, 83800 Toulon, France. Electronic address:
    Pseudomonas aeruginosa, a ubiquitous Gram-negative bacillus characterized by its greenish color and sweetish smell, is at the origin of potentially severe forms of dermatosis, such as ecthyma gangrenosum which marks immunosuppression or reveals blood-poisoning, especially in children. It frequently colonizes chronic wounds and serious burns, and spongiotic or acantholytic dermatosis, especially when severe or localized in skinfolds. It requires special care because of its high resistance to antibiotics and antiseptics. Read More

    Skin and soft tissue infections, active component, U.S. Armed Forces, 2013-2016.
    MSMR 2017 Jul;24(7):2-11
    During the 4-year surveillance period, there were 282,571 incident cases of skin and soft tissue infection (SSTI) among active component U.S. military members diagnosed in inpatient or outpatient settings, corresponding to an overall incidence of 558. Read More

    Acne keloidalis nuchae: risk factors and associated disorders - a retrospective study.
    Int J Dermatol 2017 Aug 30;56(8):828-832. Epub 2017 Jun 30.
    Department of Medicine, University of the West Indies, Kingston 7, Jamaica.
    Background: Acne keloidalis nuchae (AKN) is a chronic scarring folliculitis which usually occurs in young adult males of African descent. Studies have suggested that AKN may be associated with other dermatologic conditions and even general medical disorders. The aim of this study was to identify cutaneous and extracutaneous associated disorders and to examine risk factors in our population for developing AKN. Read More

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