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    Extreme Phenotype of Epidermal Growth Factor Receptor Inhibitor-induced Destructive Folliculitis.
    Int J Trichology 2016 Oct-Dec;8(4):176-179
    Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
    Due to the increasingly widespread use and side effect profile of epidermal growth factor receptor inhibitors (EGFRIs), cutaneous side effects of these drugs are frequently encountered. The EGFR is expressed on keratinocytes and fibroblasts. Inhibition of EGFR can produce a range of cutaneous adverse effects, the most frequent being a characteristic acneiform skin eruption. Read More

    Imatinib mesylate-induced lichenoid drug eruption.
    Cutis 2017 Mar;99(3):189-192
    Department of Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, USA.
    Imatinib mesylate (imatinib) is a tyrosine kinase inhibitor initially approved by the US Food and Drug Administration in 2001 for chronic myeloid leukemia (CML). Since then, the number of indicated uses for imatinib has substantially increased. It is increasingly important that dermatologists recognize adverse cutaneous manifestations of imatinib and are aware of their management and outcomes to avoid unnecessarily discontinuing a potentially lifesaving medication. Read More

    Skin diseases of the vulva: Infectious diseases.
    J Obstet Gynaecol 2017 Apr 11:1-9. Epub 2017 Apr 11.
    a Department of Dermatology , Bispebjerg Hospital , Copenhagen , Denmark.
    A multitude of infectious diseases of viral (genital herpes, herpes zoster, genital warts and molluscum contagiosum), bacterial (syphilis, chancroid, lymphogranuloma venereum, donovanosis, erysipelas, cellulitis and necrotising fasciitis, folliculitis, impetigo, bartholin gland abscess, trichomycosis and erythrasma), fungal (candidiasis and dermatophytosis) and parasitic (pediculosis pubis) origin may affect the vulvar area. Herein, we review the infections and their skin manifestations in the vulvar area. Read More

    Retrospective evaluation of concomitant cetuximab and radiotherapy tolerance for locoregional advanced head and neck squamous cell carcinoma treatment in patients unfit for platinum-based chemotherapy.
    Eur Arch Otorhinolaryngol 2017 Apr 5. Epub 2017 Apr 5.
    Department of Radiotherapy, Head and Neck Unit, Centre François Baclesse, 14000, Caen, France.
    Radiotherapy associated with cetuximab (Cet-RT) is an alternative treatment to platinum-based chemoradiotherapy in locally advanced head and neck carcinoma (LAHNC). Reviews suggest that the use of cetuximab is associated with poorer tolerance in patients unfit for chemotherapy than in pivotal trial. We retrospectively studied patients first treated by Cet-RT for LAHNC presenting contraindications to chemoradiotherapy. Read More

    Review in peeling complications.
    J Cosmet Dermatol 2017 Mar 27. Epub 2017 Mar 27.
    Department of Dermatology, HUB, University of Brasilia, Brasilia, Brazil.
    Chemical peeling, a procedure wherein a chemical agent is applied to the skin to cause controlled destruction followed by regeneration and remodeling, is a dynamic tool for the treatment of acne, pigmentation issues, and photoaging [Journal of cutaneous and aesthetic surgery vol. 5 (2012) 254-260]. The results and complications are related to the depth of the procedure, with deeper peels producing more marked results and higher rates of complications. Read More

    Lichenoid folliculitis, a unifying concept.
    J Cutan Pathol 2017 Mar 26. Epub 2017 Mar 26.
    Department of Dermatology, Uniformed Services University of the Health Sciences, Los Angeles, California and Bethesda, Maryland.
    Skin diseases presenting with keratotic papules, atrophy, cicatricial alopecia, and/or "lichenoid" histopathologic changes have been described under at least 30 names. This family of diseases contains two subgroups, largely based on clinical features: keratosis pilaris atrophicans (KPA; including keratosis pilaris atrophicans faciei/ulerythema ophryogenes, atrophoderma vermiculata , and keratosis follicularis spinulosa decalvans); and the lichen planopilaris (LPP) subgroup (including LPP, frontal fibrosing alopecia, Graham-Little-Piccardi-Lassueur Syndrome, and fibrosing alopecia in a pattern distribution). An interface dermatitis with lichenoid inflammation is characteristic of the LPP group of disorders, but the literature provides scant information about the histopathology of the KPA group. Read More

    Real-Time PCR Identification of Six Malassezia Species.
    Curr Microbiol 2017 Jun 22;74(6):671-677. Epub 2017 Mar 22.
    Fungal and Parasitic Molecular Biology Laboratory, Faculty of Medicine, University of Sfax, Rue Magida Boulila, Sfax, 3029, Tunisia.
    Lipophilic yeast Malassezia species is widely found on the skin surface of humans and other animals. This fungus can cause pityriasis versicolor, Malassezia folliculitis, and seborrheic dermatitis. Still now, there is a problem with species identification of Malassezia with conventional methods. Read More

    Eosinophilic Pustular Folliculitis in Children after Stem Cell Transplantation: An Eruption Distinct from Graft-Versus-Host Disease.
    Pediatr Dermatol 2017 Mar 20. Epub 2017 Mar 20.
    Department of Pediatrics, University of California, San Francisco, California.
    Eosinophilic pustular folliculitis (EPF) is a rare cutaneous disorder that typically occurs in three clinical contexts: men, individuals who are immunosuppressed or have human immunodeficiency virus, and infants. A fourth subtype occurring 2 to 3 months after hematopoietic stem cell transplantation (HSCT) has recently been described in several adults. We report two cases of EPF arising in children after HSCT. Read More

    Pruritic folliculitis of pregnancy.
    An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):66-68
    Universidade Federal Fluminense (UFF) - Niterói (RJ), Brazil.
    Pruritic folliculitis of pregnancy is a rare disease of unknown etiology. It occcurs primarily during pregnancy, usually with spontaneous resolution postpartum. It is characterized by a benign dermatosis, with papular and pustular follicular lesions that first appear on the torso and occasionally spread throughout the body. Read More

    Acquired perforating dermatosis in a patient with chronic renal failure.
    An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):10-13
    Universidade Federal do Estado do Rio de Janeiro (UNIRIO) - Rio de Janeiro (RJ), Brazil.
    Perforating dermatoses are a group of skin diseases characterized by transepidermal elimination of dermal material. The disease is divided into two groups: the primary group and the secondary group. The classical or primary perforating dermatoses are subdivided into four types according to the eliminated dermal materials: Kyrle disease, perforating reactive collagenosis, elastosis perforans serpiginosa, and perforating folliculitis. Read More

    Keloid and Hypertrophic Scars Are the Result of Chronic Inflammation in the Reticular Dermis.
    Int J Mol Sci 2017 Mar 10;18(3). Epub 2017 Mar 10.
    Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School Hospital, Tokyo 113-8603, Japan.
    Keloids and hypertrophic scars are caused by cutaneous injury and irritation, including trauma, insect bite, burn, surgery, vaccination, skin piercing, acne, folliculitis, chicken pox, and herpes zoster infection. Notably, superficial injuries that do not reach the reticular dermis never cause keloidal and hypertrophic scarring. This suggests that these pathological scars are due to injury to this skin layer and the subsequent aberrant wound healing therein. Read More

    A case of congenital folliculitis caused by Pseudomonas aeruginosa in a preterm neonate.
    Jpn J Infect Dis 2017 Feb 28. Epub 2017 Feb 28.
    Division of Neonatology, Tokyo Metropolitan Children's Medical Center.
    Intrauterine infections are associated with life-threatening neonatal conditions such as sepsis, intracranial hemorrhage, and chronic lung disease. Herein we present a case of generalized congenital folliculitis caused by Pseudomonas aeruginosa (P. aeruginosa) in a preterm neonate of 27 weeks gestational age successfully treated with antibiotics. Read More

    Acne necrotica (necrotizing lymphocytic folliculitis): An enigmatic and under-recognised dermatosis.
    Australas J Dermatol 2017 Feb 27. Epub 2017 Feb 27.
    Sherwood Road Dermatology, Brisbane, Queensland, Australia.
    Acne necrotica is a disorder of adults of obscure aetiology, featuring repeated cropping of inflammatory papulonodules which rapidly necrotise, leaving varying degrees of superficial scarring with pathological features in early lesions of a necrotising lymphocytic folliculitis. A perceived diminishing interest in this entity in recent years prompted a prospective study of patients presenting to a dermatology practice over a 3-year period to reassess the prevalence of this disorder in general dermatological patients, leading to the identification of 47 patients (35 female) with features of acne necrotica, with histopathology undertaken in atypical cases. We identified the importance of the recognition of primary lesions (1-2 mm umbilicated erythematous papules), often difficult to find in excoriated areas, as being paramount in the diagnosis both clinically and histologically in our study, which reveals a significantly more prevalent and clinically diverse disorder than featured in previous textbook and academic journal descriptions. Read More

    Secondary cutaneous peripheral T-cell lymphoma, unspecified, with generalized benign-looking dermatitis: a possibly distinct peripheral T-cell lymphoma.
    Int J Dermatol 2017 Feb 27. Epub 2017 Feb 27.
    Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
    Background: Cutaneous lymphomas are a heterogeneous group of tumors with various clinical manifestations, histological features, and prognoses.

    Methods: Among 425 cases of cutaneous lymphoma, we describe eight cases of peripheral T-cell lymphoma, unspecified, presenting with generalized benign-looking dermatitis.

    Results: Our case series included eight cases of secondary cutaneous peripheral T-cell lymphoma, unspecified. Read More

    Photodynamic Therapy and Skin Appendage Disorders: A Review.
    Skin Appendage Disord 2017 Jan 8;2(3-4):166-176. Epub 2016 Dec 8.
    Section of Dermatology, Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
    Photodynamic therapy (PDT) is a noninvasive treatment that utilizes light treatment along with application of a photosensitizing agent. In dermatology, PDT is commonly used and approved for the treatment of oncological conditions such as actinic keratosis, Bowen disease and superficial basal cell carcinoma. In the last 2 decades however, PDT has also been used for the treatment of several nonneoplastic dermatological diseases. Read More

    Disseminate and recurrent infundibulo-folliculitis in an Indian patient: A case report with review of literature.
    Indian Dermatol Online J 2017 Jan-Feb;8(1):39-41
    Department of Pathology, Government Medical College, Trivandrum, Kerala, India.
    A 17-year-old male patient presented with multiple discrete and confluent monomorphic skin-colored pinhead-sized follicular papules, with occasional pustules distributed on the neck, upper chest, upper posterior trunk, and proximal extremities of 4 months duration. The lesions were asymptomatic, and there was no prior history of topical application or history of atopic dermatitis. Routine investigations were normal. Read More

    [The alpha-herpesviridae in dermatology : Herpes simplex virus types I and II. German version].
    Hautarzt 2017 Mar;68(3):181-186
    Department of Dermatology, CHU of Sart Tilman, University of Liège, 4000, Liège, Belgien.
    This review on herpes simplex virus type I and type II (HSV-I, HSV-II) summarizes recent developments in clinical manifestations and treatment interventions for primary and recurrent orolabial and genital herpes, as well as those regarding vaccination issues. Among the clinical presentations, the relationship between pyogenic granuloma and chronic HSV-I infection; HSV-related folliculitis; verrucous HSV-I and HSV-II lesions; the role of recurrent HSV-I infection in burning mouth syndrome; HSV-I and HSV-II infection of the periareolar area; zosteriform HSV; the "knife-cut sign"; and the preferential colonization and infection of preexisting dermatoses by HSV-I or HSV-II are discussed. The usual antiviral treatment regimens for primary and recurrent orolabial and genital herpes are compared to short-term and one-day treatment options. Read More

    The alpha-herpesviridae in dermatology : Herpes simplex virus types I and II.
    Hautarzt 2017 Feb 14. Epub 2017 Feb 14.
    Department of Dermatology, CHU of Sart Tilman, University of Liège, 4000, Liège, Belgium.
    This review on herpes simplex virus type I and type II (HSV‑I, HSV‑II) summarizes recent developments in clinical manifestations and treatment interventions for primary and recurrent orolabial and genital herpes, as well as those regarding vaccination issues. Among the clinical presentations, the relationship between pyogenic granuloma and chronic HSV‑I infection; HSV-related folliculitis; verrucous HSV‑I and HSV‑II lesions; the role of recurrent HSV‑I infection in burning mouth syndrome; HSV‑I and HSV‑II infection of the periareolar area; zosteriform HSV; the "knife-cut sign"; and the preferential colonization and infection of preexisting dermatoses by HSV‑I or HSV‑II are discussed. The usual antiviral treatment regimens for primary and recurrent orolabial and genital herpes are compared to short-term and one-day treatment options. Read More

    Infection in burn patients in a referral center in Colombia.
    Burns 2017 May 6;43(3):642-653. Epub 2017 Feb 6.
    University Hospital of Santander, Universidad Industrial de Santander, Colombia. Electronic address:
    Introduction: Worldwide, burns are responsible for more than 300,000 deaths annually; infection is a major cause of morbidity and mortality in these patients. Early identification and treatment of infection improves outcome. Toward this end it's necessary to identify the institutions flora and organisms that most frequently produces infection. Read More

    Emollients and moisturisers for eczema.
    Cochrane Database Syst Rev 2017 02 6;2:CD012119. Epub 2017 Feb 6.
    Dutch Association for People with Atopic Dermatitis (VMCE: Vereniging voor Mensen met Constitutioneel Eczeem), PO Box 26, Nijkerk, Netherlands, NL-3860AA.
    Background: Eczema is a chronic skin disease characterised by dry skin, intense itching, inflammatory skin lesions, and a considerable impact on quality of life. Moisturisation is an integral part of treatment, but it is unclear if moisturisers are effective.

    Objectives: To assess the effects of moisturisers for eczema. Read More

    Expression of epithelial sodium channel (ENaC) and CFTR in the human epidermis and epidermal appendages.
    Histochem Cell Biol 2017 Jan 27. Epub 2017 Jan 27.
    Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
    A major function of the skin is the regulation of body temperature by sweat secretions. Sweat glands secrete water and salt, especially NaCl. Excreted water evaporates, cooling the skin surface, and Na(+) ions are reabsorbed by the epithelial sodium channels (ENaC). Read More

    A novel case of renal pathergy reaction in a Behçet's disease patient complicated by IgA vasculitis.
    BMC Nephrol 2017 Jan 28;18(1):40. Epub 2017 Jan 28.
    Department of Nephrology, Tokyo Teishin Hospital, 2-14-23, Fujimi, Chiyoda-ku, 102-8798, Tokyo, Japan.
    Background: A pathergy reaction is defined as a hyperreactivity of the skin in response to minimal trauma, which is important in the diagnosis of Behçet's disease (BD). However, a pathergy reaction may not be restricted to the skin, and little is known about whether an invasive medical procedure can induce the reaction. Here we present a pathergy reaction induced by renal biopsy, an invasive procedure. Read More

    Boils at Frictional Locations in a Patient with Hidradenitis Suppurativa.
    Acta Dermatovenerol Croat 2016 Dec;24(4):303-304
    Jurr Boer, MD, PhD, Department of Dermatology Deventer Hospital, Nico Bolkesteinlaan 75, 7416 SE Deventer, The Netherlands;
    Dear Editor, Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory skin disease. The primary clinical presentation are painful inflamed nodules or boils of inverse areas, i.e. Read More

    Draft Genome Sequence of an Erythromycin-Resistant Propionibacterium acnes Isolate Recovered from Folliculitis of the Scalp.
    Genome Announc 2017 Jan 26;5(4). Epub 2017 Jan 26.
    Bacteriology and Hygiene department, Nantes University Hospital, Nantes, France
    Propionibacterium acnes is now well-known and recognized for its implication in the pathogenesis of acne vulgaris. Here, we report the draft genome sequence of an erythromycin-resistant P. acnes strain isolated from a case of folliculitis of the scalp belonging to phylotype IA1 and sequence type 18 (ST18). Read More

    Molecular Identification of Malassezia Species in Patients with Malassezia folliculitis in Sfax, Tunisia.
    Mycopathologia 2017 Jan 20. Epub 2017 Jan 20.
    Laboratory of Molecular Biology of Parasite and Fungy, Medical Institute, Sfax University, Sfax, Tunisia.
    Aim: Malassezia folliculitis is caused by the invasion of hair follicles by large numbers of Malassezia cells. Several Malassezia researches still use cultures, morphology and biochemical techniques. The aim of this study was to identify Malassezia species isolated from patients diagnosed with folliculitis, at the Parasitology and Mycology Laboratory of Sfax University Hospital, and to explore the genetic diversity of Malassezia by using PCR-RFLP and PCR-sequencing targeting the rDNA region of the Malassezia genome. Read More

    A Case of Therapy-Resistant Folliculitis due to Adrenal Insufficiency?
    Case Rep Dermatol 2016 Sep-Dec;8(3):267-271. Epub 2016 Oct 4.
    Department of Dermatology, Aarhus University Hospital, Aarhus, Denmark.
    A report on a 40-year-old patient with recalcitrant, suppurative folliculitis is presented. After years of unsuccessful treatment with conventional therapies, the patient was diagnosed with adrenal insufficiency with a low level of circulating cortisol. A few weeks after the patient was subjected to substitution therapy with hydrocortisone, his folliculitis resolved. Read More

    Seasonal leukotrichia in a German shepherd dog. A case report.
    Tierarztl Prax Ausg K Kleintiere Heimtiere 2017 Feb 17;45(1):46-51. Epub 2017 Jan 17.
    Janine Classen, Medizinische Kleintierklinik, Zentrum für klinische Kleintiermedizin, Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München, E-Mail:
    Leukotrichia can be caused by a variety of metabolic and inflammatory diseases. Canine alopecia areata is a rare multifactorial benign non-scarring alopecia. This case report describes a seasonally recurrent leukotrichia associated with alopecia areata in a German shepherd dog. Read More

    Demodex spp. Infestation Associated with Treatment-Resistant Chalazia and Folliculitis.
    Turkiye Parazitol Derg 2016 Dec;40(4):208-210
    Yıldırım Beyazıt Üniversitesi Yenimahalle Eğitim ve Araştırma Hastanesi, Tıbbi Mikrobiyoloji Kliniği, Ankara, Türkiye.
    Demodecidosis is an ectoparasitosis of pilosebaceous unit caused by demodex mites. The disease may be a primary skin disease or a secondary disease to inflammatory dermatoses such as folliculitis and rosacea. Demodex spp. Read More

    Epidermal psoriasiform hyperplasia, an unrecognized sign of folliculitis decalvans: A histological study of 26 patients.
    J Cutan Pathol 2017 Apr 27;44(4):352-357. Epub 2017 Jan 27.
    Hôpital Saint-Louis, Centre Sabouraud, Paris, France.
    Background: Follicular hyperkeratosis along with hyperplasia of the follicular and interfollicular epithelia are major histopathological characteristics of hidradenitis suppurativa (HS). The presence of an occasional thickening of lesional skin in some folliculitis decalvans (FD) patients and histological similarities between FD and HS led us to look for epidermal hyperplasia and follicular hyperkeratosis in FD patients.

    Patients And Method: We performed a retrospective histological analysis of 26 patients with FD. Read More

    Clinicopathologic analysis of atypical hand, foot, and mouth disease in adult patients.
    J Am Acad Dermatol 2017 Apr 24;76(4):722-729. Epub 2016 Dec 24.
    Clinique Dermatologique, Faculté de Médecine, Université de Strasbourg et Hôpitaux, Universitaires de Strasbourg, Strasbourg, France.
    Background: Hand, foot, and mouth disease is a contagious viral infection usually affecting children. A resurgence of cases in adults, mainly caused by coxsackievirus A6 and with an atypical and more severe presentation, has taken place.

    Objective: The goal was to examine the clinical, histologic, and immunohistochemical features of this disease in adults. Read More

    Nigerian Female with Skin Lesions in the Leg and Face: Herpetic Sycosis Folliculitis.
    Case Rep Infect Dis 2016 27;2016:7948497. Epub 2016 Nov 27.
    Orange Park Medical Center Family Medicine GME, 2021 Professional Center Drive, Suite 100, Orange Park, FL 32073, USA.
    Nongenital HSV 1 presents outside the mucus membrane. Our patient had unusual presentation that caused diagnostic dilemma. 30-year-old native Nigerian female coming with fiancée to the United States presented to our service one day after arrival through ER with a lesion on her right ankle. Read More

    Acne keloidalis nuchae: prevalence, impact, and management challenges.
    Clin Cosmet Investig Dermatol 2016 14;9:483-489. Epub 2016 Dec 14.
    Dermatology Unit, Department of Medicine, College of Medicine, University of Ibadan, University College Hospital Ibadan, Oyo State, Nigeria.
    Acne keloidalis nuchae (AKN) also known as folliculitis keloidalis nuchae (FKN) is a chronic form of scarring folliculitis seen mostly in men of African descent. The term AKN is commonly used even though the condition is not a keloid, and the affected individuals do not have a tendency to develop keloids in other areas of the body. It is seen in post pubertal men and is rare after the age of 55 years. Read More

    DEBS - a unification theory for dry eye and blepharitis.
    Clin Ophthalmol 2016 9;10:2455-2467. Epub 2016 Dec 9.
    Department of Ophthalmology, Nassau University Medical Center, Hofstra University School of Medicine, East Meadow, NY, USA.
    For many years, blepharitis and dry eye disease have been thought to be two distinct diseases, and evaporative dry eye distinct from aqueous insufficiency. In this treatise, we propose a new way of looking at dry eye, both evaporative and insufficiency, as the natural sequelae of decades of chronic blepharitis. Dry eye is simply the late form and late manifestation of one disease, blepharitis. Read More

    Aeromonas as a Cause of Purulent Folliculitis: A Case Report and Review of the Literature.
    J Pediatric Infect Dis Soc 2017 Mar;6(1):e1-e3
    Division of Infectious Diseases, Department of Medicine, Boston Children's Hospital, Massachusetts.
    Aeromonas species are rarely an identified cause of folliculitis. Here, we describe the case of a patient who had purulent folliculitis of the breast caused by an Aeromonas species and review 4 other cases presented in the literature, highlighting the commonalities observed. Aeromonas infection should be considered in patients who present with purulent folliculitis, particularly those with exposure to nonchlorinated pools or baths. Read More

    Cutaneous Reactions in Children Treated with the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase Inhibitor Trametinib for Neural Tumors.
    Pediatr Dermatol 2017 Jan 16;34(1):90-94. Epub 2016 Dec 16.
    Division of Pediatric Dermatology, Department of Dermatology, University of Minnesota, Minneapolis, Minnesota.
    Background: The mitogen-activated protein kinase (MAPK) pathway is a target for the treatment of a growing number of malignancies. The cutaneous reactions to medications that inhibit this pathway have not been described in children.

    Methods: A retrospective chart review was completed for eight children with neural tumors treated with the MAPK extracellular signal-regulated kinase inhibitor trametinib. Read More

    Acute skin and hair symptoms followed by severe, delayed eye complications in subjects using the synthetic opioid MT-45.
    Br J Dermatol 2017 Apr 14;176(4):1021-1027. Epub 2016 Dec 14.
    Dermatology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.
    Background: The introduction of unclassified new psychoactive substances (NPS) on the recreational drugs market through open online sale ('legal highs' or 'Internet drugs') continues unabated and represents a growing health hazard. The use of NPS has resulted in numerous, severe, adverse events and fatalities, due to unintended overdose or unknown toxic side-effects.

    Objectives: To try to find a possible common underlying cause for the skin-hair-eye symptoms complex observed in three men. Read More

    Behçet syndrome: the vascular cluster.
    Turk J Med Sci 2016 Nov 17;46(5):1277-1280. Epub 2016 Nov 17.
    Department of Rheumatology, Cerrahpaşa Faculty of Medicine, İstanbul University, İstanbul, Turkey.
    Although skin-mucosa lesions are common in almost all patients with Behçet syndrome (BS), clinical properties may differ from one patient to another. Within BS, there are subsets with different organ involvement and hence probably different pathological pathways. These subsets can be described as a) solo skin-mucosa disease with no major organ involvement, b) eye disease, c) seronegative spondyloarthropathy-like disease (arthritis, enthesopathy, and folliculitis), d) Crohn-like disease, and finally the topic of this chapter: e) vascular disease. Read More

    Endothelial dysfunction may play a key role in keloid and hypertrophic scar pathogenesis - Keloids and hypertrophic scars may be vascular disorders.
    Med Hypotheses 2016 Nov 28;96:51-60. Epub 2016 Sep 28.
    Department of Plastic, Reconstructive and Aesthetic Surgery, Nippon Medical School, Tokyo, Japan.
    Keloids and hypertrophic scars are fibroproliferative disorders (FPDs) of the skin that result from abnormal healing of injured or irritated skin. They can be called pathological or inflammatory scars. Common causes are trauma, burn, surgery, vaccination, skin piercing, folliculitis, acne, and herpes zoster infection. Read More

    Non-dermatophyte Dermatoses Mimicking Dermatophytoses in Animals.
    Mycopathologia 2017 Feb 16;182(1-2):113-126. Epub 2016 Nov 16.
    UP Interactions Cellules Environnement, VetAgro Sup, Univ Lyon, 69280, Marcy l'Etoile, France.
    Dermatophytoses in animals are fungal diseases of the skin caused by dermatophyte fungi of the genus Microsporum or Trichophyton. Because the infection is generally follicular, the most common clinical sign is one or many circular areas of alopecia with variable erythema, scaling and crusting, and the primary differential diagnoses are follicular infections, such as bacterial folliculitis and demodicosis. Although dermatophyte folliculitis or ringworm is the most commonly observed lesion of dermatophytoses in animals, other presentations may be observed according to the host species and the dermatophyte involved: dermatophyte folliculitis or ringworm, scaling and crusting in dermatophytosis due to Microsporum persicolor, nodule in case of kerion or mycetoma, matted hairs, seborrheic dermatosis or miliary dermatitis in cats, generalized exfoliative dermatoses in dogs, cats and horses, superficial non-follicular pustules, papules and macules in the Devon Rex cat, pruritic dermatophytoses in dogs, cats and horses, and onychomycosis in dogs, cats and horses. Read More

    Primary cicatricial alopecia: Other lymphocytic primary cicatricial alopecias and neutrophilic and mixed primary cicatricial alopecias.
    J Am Acad Dermatol 2016 Dec;75(6):1101-1117
    Department of Dermatology, University of British Columbia, Vancouver, British Columbia, Canada; Department of Dermatology, New York University, New York, New York.
    Primary cicatricial alopecias can be frustrating for both patients and physicians. Proper diagnosis guides more successful management of these challenging conditions. Part II will cover the remaining lymphocytic primary cicatricial alopecias, which include pseudopelade of Brocq, central centrifugal cicatricial alopecia, alopecia mucinosa, and keratosis follicularis spinulosa decalvans. Read More

    Ofuji disease: a rare dermatosis and its challenging therapeutic approach.
    An Bras Dermatol 2016 Sep-Oct;91(5):646-648
    Instituto Lauro de Souza Lima (ILSL) - Bauru (SP), Brazil.
    Eosinophilic pustular folliculitis (EPF) or Ofuji disease is a rare dermatosis, prone to recurrence and chronicity. The peak incidence occurs in the third decade of life and its exact etiology remains unknown. Evidence suggests that the expression of adhesion molecules and the production of cytokines activate the follicular unit, but the stimulus that triggers these changes remains unclear. Read More

    [Cutaneous lesions during hot-tub hypersensitivity pneumonitis: Pseudomonas folliculitis ?]
    Ann Dermatol Venereol 2017 Apr 4;144(4):290-294. Epub 2016 Nov 4.
    Service de dermatologie, hôpital Saint-André, CHU de Bordeaux, rue Jean-Burguet, 33076 Bordeaux, France. Electronic address:
    Background: Interstitial lung disease, cutaneous rash and elevated serum angiotensin converting enzyme (ACE) may suggest diagnoses other than sarcoidosis.

    Patients And Methods: A 58-year-old man had presented dyspnoea for 2 years with increased angiotensin-converting enzyme, as well as an interstitial syndrome and micronodules. The possibility of sarcoidosis was raised. Read More

    An unusual case of folliculitis spinulosa decalvans.
    Cutis 2016 Sep;98(3):175-178
    Department of Dermatology, The First Hospital Affiliated to Soochow University, Suzhou, Jiangsu Province, China.
    We report the case of a 24-year-old man who presented with pustules, atrophic scars, and alopecia on the scalp, along with follicular keratotic papules on the cheeks, chest, abdomen, back, lateral upper arms, thighs, and axillae, of 6 years' duration. A diagnosis of folliculitis spinulosa decalvans (FSD) was made based on the clinical manifestation and histopathological findings. Dental examination also revealed dental anomalies and a fissured tongue, which are not known to be related to FSD. Read More

    Factors affecting the rise of treatment of resistant bacteria in skin and soft tissue infections in the United States: 1993-2012().
    J Dermatolog Treat 2016 Nov 22:1-5. Epub 2016 Nov 22.
    a University of Kentucky College of Medicine , Lexington , KY , USA.
    Background: Methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections (SSTIs) prevalence has been steadily increasing for the past 40 years. The increase in such infections has contributed to a change in the treatment patterns of the patient. This study aimed to detail the factors determining prescription practices associated with MRSA-related skin and soft tissue infections. Read More

    Pilosebaceous targeting by isotretenoin-loaded invasomal gel for the treatment of eosinophilic pustular folliculitis: optimization, efficacy and cellular analysis.
    Drug Dev Ind Pharm 2017 Feb 2;43(2):293-304. Epub 2016 Nov 2.
    c Department of Pharmaceutics , Pharmacy College Saifai, UPRIMS & R , Saifai, Etawah , Uttar Pradesh , India.
    Context: Eosinophilic pustular folliculitis is a secondary symptom associated with HIV infection appears as levels of CD4 lymphocyte cells and T4 lymphocyte cell. Isotretinoin, an analog of vitamin A (retinoid) alters the DNA transcription mechanism and interferes in the process of DNA formation. It also inhibits the eosinophilic chemotactic factors present in sebaceous lipids and in the stratum corneum of patients suffering from this ailment. Read More

    MRSA infections among patients in the emergency department: a European multicentre study.
    J Antimicrob Chemother 2017 Feb 17;72(2):372-375. Epub 2016 Oct 17.
    National Reference Center for Staphylococci, 59 Bd Louis Pinel, 69677 Bron cedex, Lyon, France.
    Background: MRSA is a therapeutic concern worldwide, and a major agent of community-acquired skin and soft tissue infections (CA-SSTIs). While the US epidemiology of MRSA in CA-SSTIs is well described and reports the high prevalence of the USA300 clone, data on the European situation are lacking.

    Objectives: To determine the prevalence and clonal characteristics of MRSA in CA-SSTIs in seven European emergency departments. Read More

    Eosinophilic pustular folliculitis: A proposal of diagnostic and therapeutic algorithms.
    J Dermatol 2016 Nov 30;43(11):1301-1306. Epub 2016 Mar 30.
    Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
    Eosinophilic pustular folliculitis (EPF) is a sterile inflammatory dermatosis of unknown etiology. In addition to classic EPF, which affects otherwise healthy individuals, an immunocompromised state can cause immunosuppression-associated EPF (IS-EPF), which may be referred to dermatologists in inpatient services for assessments. Infancy-associated EPF (I-EPF) is the least characterized subtype, being observed mainly in non-Japanese infants. Read More

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