35 results match your criteria Florid Cutaneous Papillomatosis


[Hyperplasia-associated cutaneous paraneoplasia].

Hautarzt 2021 Apr 3;72(4):295-298. Epub 2021 Mar 3.

Klinik für Dermatologie und Allergologie, Hautklinik, Universitätsklinikum Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland.

Background: Hyperplasia-associated cutaneous paraneoplasia is an important differential diagnosis in everyday clinical practice. An early diagnosis of the underlying tumor disease can significantly improve the patient's prognosis.

Pathogenesis: Hyperplasia is probably mainly cytokine-mediated. Read More

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Florid cutaneous and mucosal papillomatosis in a patient with gastric adenocarcinoma.

Eur J Dermatol 2020 Apr 16. Epub 2020 Apr 16.

Department of medical oncology, lung cancer and gastrointestinal unit, Hunan cancer hospital/The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.

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[Malignant acanthosis nigricans associated with cholangiocarcinoma].

Rev Med Interne 2019 Nov 26;40(11):750-753. Epub 2019 Sep 26.

Service de dermatologie, CHU d'Angers, 4, rue Larrey, 49100 Angers, France.

Introduction: Acanthosis nigricans is a dermatosis characterized by the presence of a hyperpigmented, velvety cutaneous thickening in the flexural areas, especially axillary and inguinal fossas, and lateral faces of the neck. AN is usually a benign condition but can sometimes reveal an internal malignancy corresponds to a cutaneous paraneoplasic syndrome. Literature shows a predominant association with gastric adenocarcinoma. Read More

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November 2019

Malignant Acanthosis Nigricans: An Indicator of Internal Malignancy.

J Coll Physicians Surg Pak 2019 Sep;29(9):888-890

Department of Dermatology, Pak Emirates Military Hospital, Rawalpindi, Pakistan.

Acanthosis nigricans is a skin disease characterised by symmetric velvety hyperpigmented, verrucous plaques of the intertriginous surfaces of the axilla, neck, inframammary, and mucocutaneous regions. Malignant acanthosis nigricans is a paraneoplastic phenomenon most commonly associated with gastric adenocarcinoma. Tripe palms, florid cutaneous papillomatosis and oral involvement along with generalised acanthosis nigricans are the features which are highly suggestive of internal malignancy. Read More

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September 2019

[Paraneoplastic skin diseases].

Internist (Berl) 2019 Aug;60(8):775-782

Hautklinik und Hauttumorzentrum Rheinpfalz, Klinikum der Stadt Ludwigshafen, Bremserstraße 79, 67063, Ludwigshafen am Rhein, Deutschland.

Various specific skin alterations can occur in patients with malignant diseases. If these skin diseases occur as associated symptoms of a malignant process, they are called paraneoplastic. In this overview, obligate and frequent facultative paraneoplastic skin diseases are assigned according to the triggering type of malignancy. Read More

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Cutaneous paraneoplastic syndromes.

Semin Diagn Pathol 2019 Jul 31;36(4):211-228. Epub 2019 Jan 31.

PRW Laboratories, Charlottesville, VA, United State.

A variety of cutaneous abnormalities can be seen in patients with malignant diseases, some of which are infectious, with others representing direct involvement of the skin by the underlying disorder. Yet another group of lesions can be regarded as associated markers of the malignant process, and, as such, are termed "paraneoplastic." This review considers the latter collection of conditions, grouping them by the generic type of malignancy that is usually linked to the paraneoplasia. Read More

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Florid cutaneous papillomatosis as a marker of neoplastic recurrence.

Dermatol Online J 2018 Aug 15;24(8). Epub 2018 Aug 15.

Department of Dermatology and Venereology, Centro Hospitalar de Sao Joao EPE, Porto, Portugal.

Florid cutaneous papillomatosis is a rare paraneoplastic dermatosis, most commonly associated with gastric adenocarcinoma. It is characterized by a sudden onset of hyperkeratotic papules, clinically indistinguishable from viral warts. We report an 80-year-old man who presented to our department with a two-month history of multiple verrucous lesions affecting the face, perioral region, and hands. Read More

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Hidradenoma Papilliferum With Oncocytic Metaplasia: A Histopathological and Immunohistochemical Study.

Am J Dermatopathol 2016 Jun;38(6):444-7

*Ackerman Academy of Dermatopathology, New York, NY; †Department of Dermatology, Kasr Alainy Faculty of Medicine, Cairo University, Egypt; ‡Kings County Hospital Center, SUNY Downstate Medical Center, New York, NY; §Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, SC; and ¶Department of Dermatology, SUNY Downstate Medical Center, New York, NY.

Hidradenoma papilliferum is a benign cutaneous adnexal neoplasm, commonly occurring in the vulva and perianal region of adult women. It has characteristic histopathological features composed of anastomosing and branching tubules, lined by columnar cells, and a basal layer of myoepithelial cells. A 39-year-old woman was evaluated for 2 asymptomatic labial masses. Read More

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Malignant acanthosis nigricans, florid cutaneous and mucosal papillomatosis, and tripe palms in a man with gastric adenocarcinoma.

Actas Dermosifiliogr 2015 Jun 24;106(5):438-9. Epub 2014 Dec 24.

Servicio de Dermatología, Complejo Hospitalario Universitario de Ferrol, Área Sanitaria de Ferrol, SERGAS, Ferrol, A Coruña, España.

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Malignant acanthosis nigricans, florid cutaneous papillomatosis and tripe palms syndrome associated with gastric adenocarcinoma.

Postepy Dermatol Alergol 2014 Feb 25;31(1):56-8. Epub 2014 Feb 25.

Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, Poland. Head of Department: Prof. Roman Nowicki MD, PhD.

Malignant acanthosis nigricans is a rare paraneoplastic skin syndrome mostly associated with gastric adenocarcinoma. Florid cutaneous papillomatosis and tripe palms syndrome are considered to be abortive clinical variants of acanthosis nigricans. Clinical manifestations include pruritic, hyperkeratotic and hyperpigmented plaques with a subsequent formation of velvety papillomas in the involved areas. Read More

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February 2014

Three paraneoplastic signs in the same patient with gastric adenocarcinoma.

Dermatol Online J 2013 Jul 14;19(7):18966. Epub 2013 Jul 14.

Third Affiliated Hospital of Suzhou University. 185 Juqian Road, Changzhou, China.

This is the report of a 76-year-old male with typical lesions of acanthosis nigricans maligna (ANM), florid cutaneous papillomatosis (FCP), and tripe palms (TP) for 2 years. He did not have any gastrointestinal complaints. Pathologic findings of skin supported the diagnosis of ANM. Read More

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Florid cutaneous and mucosal papillomatosis: mucocutaneous markers of an underlying gastric malignancy.

J Clin Oncol 2013 May 25;31(13):e218-9. Epub 2013 Mar 25.

University of Toronto, Sunnybrook Health Sciences Centre, Toronto, Canada.

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Florid cutaneous papillomatosis and acanthosis nigricans maligna revealing gastric adenocarcinoma.

An Bras Dermatol 2011 May-Jun;86(3):573-7

Teaching Hospitals of the University of Coimbra; EPE Service of Dermatology, Coimbra, Portugal.

This paper reports the case of a 57-year-old, previously healthy male with no systemic symptoms who over a short period of time developed multiple wart-like lesions on his trunk, limbs and face, typical lesions of acanthosis nigricans in the major body folds and tripe palms. Diagnostic tests revealed a metastatic gastric adenocarcinoma. Despite the implementation of therapy, which had a transient effect on the tumor and skin lesions, the patient died in 14 months. Read More

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February 2012

Florid cutaneous papillomatosis.

J Surg Oncol 2010 Nov;102(6):709-12

Dermatology, New Jersey Medical School, Newark, New Jersey 07103-2714, USA.

Florid cutaneous papillomatosis is an obligate paraneoplastic syndrome. Originally described by Schwartz and Burgess, and also known as the Schwartz-Burgess syndrome, it is a widespread eruption resembling viral warts yet with no evidence of human papilloma virus infection. We review this entity and its implications. Read More

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November 2010

Malignant acanthosis nigricans with occult primary.

Indian J Dermatol Venereol Leprol 2002 Nov-Dec;68(6):371-3

Department of Dermatology and Venereology, Medical College, Kottayarn-686 008, India.

A case of generalized malignant acanthosis nigricans of 2 years duration is reported. In spite of the long duration of this cutaneous marker of internal malignancy, the patient was completely asymptomatic and extensive investigations revealed the presence of widespread metastasis of mucin secreting signet cell adenocarcinoma from an unknown primary site. In addition the patient also had acquired hypertrichosis lanuginose and florid cutaneous papillomatosis which are also markers of internal malignancy. Read More

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Florid cutaneous papillomatosis with adenocarcinoma of stomach in a 35 year old male.

Indian J Dermatol Venereol Leprol 2005 May-Jun;71(3):195-6

Department of Dermatology, Venereology and Leprosy, Dr. S. N. Medical College, Jodhpur, India.

Various paraneoplastic dermatoses may be seen in association with underlying visceral, especially gastrointestinal, malignancy. Florid cutaneous papillomatosis describes the sudden appearance of multiple acuminate keratotic papules that morphologically resemble viral warts. It may be seen in association with acanthosis nigricans and/or the sign of Leser Triotalat. Read More

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[Pseudolymphoma of the breast nipple. The problem overview].

Rozhl Chir 2005 Feb;84(2):66-9

Siklův patologicko-anatomicky ústav Fakultní nemocnice a Lékaiské fakulty Univerzity Karlovy v Plzni.

Clinical, pathological, and molecular-genetic features as well as etiology of cutaneous pseudolymphoma (CPL, cutaneous lymphoid hyperplasia, lymphocytoma cutis) of the breast nipple are summarized. CPL presents as a nipple induration and it is often suspected to be Paget carcinoma pre-operatively. Histologically, atypical microscopic features of a dense lymhoid infiltrate with follicles often mislead to the diagnosis of a malignant lymphoma. Read More

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February 2005

Florid cutaneous and mucosal papillomatosis with acanthosis nigricans revealing a primary lung cancer.

J Eur Acad Dermatol Venereol 2000 May;14(3):205-8

Istituto di Dermatologia, Università di Roma La Sapienza, Italy.

This is the report of an 80-year-old patient with diffuse brownish hyperpigmentation and velvety thickening of the skin with onset 1 year before. Warty lesions on his limbs were present as well as papillomatous and verrucous lesions on his lips, mouth and eyelid conjunctivae with hyperkeratosis of the nipples. Biopsies, performed at different sites, showed histological pictures consistent with a diagnosis of acanthosis nigricans (AN) with florid cutaneous and mucosal papillomatosis. Read More

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Coexistence of acanthosis nigricans and the sign of Leser-Trélat in a patient with gastric adenocarcinoma: a case report and literature review.

J Am Acad Dermatol 2000 Feb;42(2 Pt 2):357-62

Department of Dermatology, King's College Hospital, London, United Kingdom.

The association of acanthosis nigricans (AN) with the sign of Leser-Trélat (LT) and gastric carcinoma is rare. Our patient was a 69-year-old man, who presented with hematemesis; a stage-IV poorly differentiated, diffuse-type, adenocarcinoma of the gastric antrum was diagnosed. The AN was striking, with florid cutaneous papillomatosis that also involved the mucous membranes of the mouth and eyelids, and keratoderma. Read More

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February 2000

[Acanthosis nigricans maligna. Case report and review of the literature].

Hautarzt 1998 Jan;49(1):41-7

Abteilung für Dermatologie, Allgemeines Krankenhaus St. Georg, Hamburg.

More than 400 cases of acanthosis nigricans maligna (ANM) and 23 cases of "florid cutaneous papillomatosis" (FCP) were published. ANM is an obligatory paraneoplastic symptom. A 28-year old female patient with an adenocarcinoma of the stomach presented with ANM. Read More

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January 1998

Cutaneous paraneoplastic syndromes in solid tumors.

Am J Med 1995 Dec;99(6):662-71

Department of Clinical Investigation, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.

Objective: To provide an overview of the clinical manifestations, pathophysiology, and oncologic implications of the cutaneous paraneoplastic syndromes that occur predominantly in patients with solid tumors.

Methods: A review was performed of the literature identified by a comprehensive MEDLINE search.

Results: Diverse cutaneous paraneoplastic syndromes may be associated with underlying tumors. Read More

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December 1995

Hypertrichosis lanuginosa acquista associated with florid cutaneous papillomatosis.

Int J Dermatol 1993 Jan;32(1):56-8

Department of Dermatology, Technical University, Munich, Germany.

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January 1993

Florid cutaneous papillomatosis.

Authors:
R A Schwartz

Clin Dermatol 1993 Jan-Mar;11(1):89-91

UMD-New Jersey Medical School, Newark 07103-2714.

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September 1993

[Florid nevoid cutaneous papillomatosis disclosing lung cancer].

Ann Dermatol Venereol 1992 ;119(11):850-2

Service de Dermatologie, Hôtel-Dieu, Clermont-Ferrand.

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Florid cutaneous papillomatosis, malignant acanthosis nigricans, and pulmonary squamous cell carcinoma.

Int J Dermatol 1991 Mar;30(3):193-7

Department of Dermatology, University Hospital Saint-Pierre, Brussels, Belgium.

A 72-year-old man had florid cutaneous papillomatosis (FCP), which is an obligatory paraneoplastic syndrome always associated with an internal malignancy. The cancer, which is usually intraabdominal and most often gastric in origin, evolves parallel to the FCP. This patient is the first case of FCP occurring in association with a lung malignancy. Read More

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Malignant acanthosis nigricans associated with non-Hodgkin's lymphoma. Report of 2 cases.

Dermatologica 1988 ;176(3):133-7

Clinique des maladies cutanées et syphilitiques, Hôpital Saint-Louis, Paris, France.

Two cases of malignant acanthosis nigricans associated with non-Hodgkin's lymphoma are presented. A 61-year-old negro male with a diffuse large cell non-Hodgkin's lymphoma presented extensive acanthosis nigricans, pachydermatoglyphy and florid cutaneous papillomatosis. No viral particles were observed by electron microscopic studies of the wart-like lesions. Read More

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[Acanthosis nigricans maligna and Leser-Trélat sign in double malignancy of the breast and stomach].

Authors:
W Stieler G Plewig

Z Hautkr 1987 Mar;62(5):344-66

A female patient with primary cancer of the breast and the stomach developed acanthosis nigricans maligna and Leser-Trélat's sign. Acanthosis nigricans maligna is a well-known cutaneous marker of internal malignancy. It may be intensified by radiotherapy. Read More

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[Epithelioma cuniculatum. Apropos of a case with review of the literature].

Ann Pathol 1984 Jun-Aug;4(3):223-9

A case of Epithelioma cuniculatum arising on a leg ulcer in a 85 years old lady is described. 102 cases have been reported before, mainly located on the sole of the foot: this rare tumor may be recognized by the gross appearance of a slow-growing exophytic cauliflower growth, exuding foul smelling material from numerous sinuses, which eventually invades underlying tissue sometimes including bone, and which rarely metastasizes to the regional lymph nodes. Histological examination shows a well-differentiated squamous epithelial proliferation without cellular atypia, with numerous crypts and sinuses. Read More

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November 1984