487 results match your criteria Fissured Tongue

Oral manifestations in patients diagnosed with psoriasis: A systematic review.

Spec Care Dentist 2022 Jun 17. Epub 2022 Jun 17.

Adjunct Professor at Bahiana - School of Medicine and Public Health, Salvador, Bahia, Brazil.

Aims: To identify the main types of oral lesions associated with psoriasis.

Methods And Results: It was a systematic review, based on a search performed in the PubMed/Medline, and Scielo databases, and an associated manual search. Descriptors were selected from DeCs/MeSH and the PICOS strategy (population, intervention, comparison, outcomes, and study design) was applied. Read More

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Oral Lesions in Patients With Psoriasis: Prevalence and Association With Its Clinical and Epidemiological Characteristics.

Actas Dermosifiliogr 2022 May 31;113(5):459-466. Epub 2022 Jan 31.

Servicio de Dermatología, Hospital Universitari Sagrat Cor, Grupo Hospitalario Quirónsalud, Barcelona, España.

Background And Objective: Psoriasis is a multisystem disease associated with an increased prevalence of oral lesions. The aim of this study was to determine the prevalence of oral lesions in patients with psoriasis and examine associations with clinical and patient characteristics.

Material And Methods: We conducted a cross-sectional study of patients with psoriasis and healthy controls seen between December 2019 and February 2020. Read More

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Tongue Lesions as an Oral Diagnostic Challenge for a Primary Care Physician- A Clinical Case series.

Praveena Raman

J Family Med Prim Care 2022 Apr 18;11(4):1573-1579. Epub 2022 Mar 18.

Department of Oral Medicine and Radiology, Sathyabama Dental College and Hospital, Chennai, Tamil Nadu, India.

Tongue acts as a mirror of our body. Diagnosis of tongue lesions is challenging to primary physicians as they might be the first sign or may be a part of underlying systemic diseases. Knowledge on the lesions of tongue is necessary for oral and overall health planning and education. Read More

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The PTEN Hamartoma Tumor Syndrome: How Oral Clinicians May Save Lives.

Clin Adv Periodontics 2022 Mar 30. Epub 2022 Mar 30.

Western Norway Familial Cancer Center, Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway.

Introduction: Patients with the PTEN hamartoma tumor syndrome (PHTS) have an 81%-90% cumulative lifetime risk of developing cancer. Around 90% of these patients have recognizable oral features. Receiving a diagnosis may save these patients' lives. Read More

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Melkersson-Rosenthal syndrome: a rare variant of the monosymptomatic form.

GMS Ophthalmol Cases 2022 8;12:Doc04. Epub 2022 Feb 8.

Hospital Federal dos Servidores do Estado do Rio de Janeiro (HFSERJ), Rio de Janeiro, Brazil.

Melkersson-Rosenthal syndrome (MRS) is a rare condition without any known etiology. It is characterized by the triad facial paralysis, facial swelling, and the development of folds and furrows at the tongue (fissured tongue). This study aims to report a case of a 59-year-old patient complaining about asymmetric eyelid swelling that had started two years before, associated with pain and redness on her right eye, without repercussions on her visual acuity. Read More

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February 2022

Classification of fissured tongue images using deep neural networks.

Technol Health Care 2022 ;30(S1):271-283

Background: Tongue inspection is vital in traditional Chinese medicine. Fissured tongue is an important feature in tongue diagnosis, and primarily corresponds to three Chinese medicine syndromes: syndrome-related hotness, blood deficiency, and insufficiency of the spleen. Diagnosis of the syndrome is significantly affected by the experience of clinicians, and it is difficult for young doctors to perform accurate diagnoses. Read More

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Pathophysiology and Management of Tongue Involvement in COVID-19 Patients.

Indian J Otolaryngol Head Neck Surg 2022 Jan 6:1-4. Epub 2022 Jan 6.

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Evaluate the lingual manifestations of COVID-19, and provide a clinical guide in managing these symptoms. Electronic databases, such as PubMed/Medline, and Scopus were searched until November 1, 2020, and only randomized controlled trials, cross-sectional and cohort studies, as well as case reports and series, and review articles in English were considered. A total of 40 studies were included in this study. Read More

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January 2022

Risk factors associated with tongue lesions: a propensity score-matched case-control study.

Med Oral Patol Oral Cir Bucal 2022 Jan 1;27(1):e25-e34. Epub 2022 Jan 1.

Department of Surgery and Medical-Surgical Specialities Faculty of Medicine and Sciences of the Health Catedrático José Serrano sn. 33006. Oviedo. Spain

Background: to analyse the potential risk factors of tongue lesions, comparing the results with a control group.

Material And Methods: An observational, case-control study was designed. The study included a case group comprising 336 patients with tongue lesions and 336 sex and age-matched controls. Read More

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January 2022

Application of U-Net with Global Convolution Network Module in Computer-Aided Tongue Diagnosis.

J Healthc Eng 2021 18;2021:5853128. Epub 2021 Nov 18.

Department of Mechanical Engineering, University of Saskatchewan, Saskatoon, Canada M4Y1M7.

The rapid development of intelligent manufacturing provides strong support for the intelligent medical service ecosystem. Researchers are committed to building Wise Information Technology of 120 (WIT 120) for residents and medical personnel with the concept of simple smart medical care and through core technologies such as Internet of Things, Big Data Analytics, Artificial Intelligence, and microservice framework, to improve patient safety, medical quality, clinical efficiency, and operational benefits. Among them, how to use computers and deep learning technology to assist in the diagnosis of tongue images and realize intelligent tongue diagnosis has become a major trend. Read More

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January 2022

Melkersson-Rosenthal syndrome in the context of sarcoidosis: a case report.

J Med Case Rep 2021 Oct 4;15(1):488. Epub 2021 Oct 4.

Department of Nephrology and Hypertension, Hanover Medical School, Carl-Neuberg-Strasse 1, 30625, Hanover, Germany.

Background: Melkersson-Rosenthal syndrome is a rare disease characterized by the triad of recurrent orofacial swelling with facial paralysis and fissured dorsal tongue. Histologically, noncaseating granulomatous inflammation occurs that confirms the diagnosis. Overlaps between granulomatous diseases such as sarcoidosis and Crohn's disease are described. Read More

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October 2021

Cerebriform Tongue.

J Pharm Bioallied Sci 2021 Jun 5;13(Suppl 1):S868-S870. Epub 2021 Jun 5.

Krishna Dental Clinic, Erode, Tamil Nadu, India.

Cerebriform tongue (CT) is diagnosed to be a benign clinical condition that is characterized by grooves on the dorsal surface of the tongue and referred with other terminologies such as the scrotal tongue, grooved tongue, lingua fissurata, and lingua plicata which can be chronic trauma, vitamin deficiencies, and probably not a developmental malformation. The incidence of this condition was predominant among males and found to be higher with increasing age. It is very rarely observed in children. Read More

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The Prevalence and Correlates of Fissured Tongue Among Outpatients in Andkhoy City, Afghanistan: A Cross-Sectional Study.

Clin Cosmet Investig Dent 2021 27;13:335-342. Epub 2021 Jul 27.

Curative Clinic, Andkoy, Faryab, Afghanistan.

Background: Fissured tongue is a common manifestation of the tongue, marked by the presence of multiple prominent grooves or fissures on the dorsal surface of the tongue. However, there is a lack of studies focusing on the prevalence and factors associated with fissured tongue among patients attending an outpatient clinic in Afghanistan.

Aim: The purpose of the current study was to determine the prevalence and factors associated with fissured tongue and its effects on the general health of adult outpatients in Afghanistan. Read More

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False cheilitis (fausse cheilitis) as a clinical manifestation of oral secondary syphilis.

Int J Dermatol 2022 Feb 21;61(2):180-183. Epub 2021 Jul 21.

Oral Medicine Department, Facultad de Odontología, Universidad Nacional de Córdoba, Córdoba, Argentina.

Background: Syphilis is the oldest sexually transmitted infectious disease in humanity. In the last decades, it was noted the re-emergence of the disease, and actually it remains an important public health problem. Oral mucosa could be affected by the infection. Read More

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February 2022

Research progress on Melkersson-Rosenthal syndrome.

Zhejiang Da Xue Xue Bao Yi Xue Ban 2021 04;50(2):148-154

Department of Oral Medicine.

Melkersson-Rosenthal syndrome (MRS) is a rare neuro-muco-cutaneous syndrome, which is characterized by recurrent orofacial swelling, recurrent facial paralysis and fissured tongue. It has a high prevalence in young adults. Up to now, the etiology of MRS is still not clear, it may related to infection, immune deficiency and hereditary factors. Read More

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Rare diagnosis of Melkersson-Rosenthal syndrome in a paediatric patient.

BMJ Case Rep 2021 Jun 11;14(6). Epub 2021 Jun 11.

Pediatrics, Medical Center Navicent Health, Macon, Georgia, USA.

Melkersson-Rosenthal syndrome (MRS) is a rare neurocutaneous syndrome characterised by the triad of recurrent orofacial swelling, facial nerve palsy and fissured tongue. This diagnosis is particularly rare in children. We aim to increase awareness of the syndromic association of these clinical features since most patients present with a monosymptomatic form, reiterating the importance of detailed history and thorough physical examination, for the timely identification of these patients. Read More

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Psoriasis is associated with fissured tongue but not geographic tongue: a prospective, cross-sectional, case-control study.

J Dtsch Dermatol Ges 2021 08 10;19(8):1170-1176. Epub 2021 Jun 10.

Department of Dermatology, Venereology and Allergology, Teaching Hospital of the Medical University Vienna, Vienna, Austria.

Background And Objectives: It has been postulated that psoriasis is associated with tongue lesions and geographic tongue might be "oral psoriasis". However, reports are inconclusive, prevalence rates vary and data for Europe are sparse. In this prospective case-control study we investigated the point-prevalence of tongue conditions in an Austrian cohort. Read More

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Recurrent facial palsy and fissured tongue.

Eur J Intern Med 2021 07 19;89:104-105. Epub 2021 May 19.

Yong Loo Lin School of Medicine, National University of Singapore, and Division of Neurology, National University Hospital, Singapore. Electronic address:

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Salivary pH and oral health of Brazilian para-athletes: Saliva and oral health of para-athletes.

Spec Care Dentist 2021 Jul 22;41(4):505-511. Epub 2021 Mar 22.

School of Dentistry, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.

Aims: This study aimed to investigate the association of the salivary pH and parameters of oral health in Brazilian para-athletes.

Methods And Results: The sample was composed of 271 Brazilian para-athletes (147 athletics, 61 powerlifting, and 63 swimming); mean age was 31.2 ± 11. Read More

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Myasthenia gravis masquerading as acute stroke: a case report.

Pan Afr Med J 2020 2;37:305. Epub 2020 Dec 2.

Department of Neurology, Sree Narayana Institute of Medical Sciences (SNIMS), Kunnukara, India.

Among non-iatrogenic neuromuscular disorders, myasthenia gravis remains the most prevalent. Diagnosing this disorder may become challenging in certain cases such as in patients with coexisting comorbid illnesses and non-specific clinical symptoms. This is a case of atypical myasthenia gravis in a middle-aged hypertensive male, who initially presented symptoms suggestive of an acute ischemic stroke. Read More

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[Recurrent peripheral facial nerve palsy].

Rev Alerg Mex 2020 Oct-Dec;67(4):421-424

Hospital Universitario de Cabueñes, Servicio de Pediatría, Gijón, España.

Background: Melkersson-Rosenthal syndrome is a rare disorder that is characterized, in its full form, by recurrent facial nerve palsy, fissured tongue, and orofacial edema. Most cases present as oligosymptomatic or monosymptomatic forms. Its etiology is still unknown and its course is chronic and it may be progressive. Read More

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October 2021

Orofacial Granulomatosis and Crohn Disease: Coincidence or Pattern? A Systematic Review.

Dermatology 2021 12;237(4):635-640. Epub 2021 Feb 12.

Department of General Pathology, Dental School, University of São Paulo, São Paulo, Brazil.

Background: To systematically review all cases of orofacial granulomatosis (OFG) and evaluate the association between OFG and Crohn disease (CD).

Summary: This review was conducted according to PRISMA guidelines and a search of the PubMed, MEDLINE, and Embase databases, and the Cochrane Library in March 2020, using keywords and MeSH terms associated with "orofacial granulomatosis," "Crohn disease," and their variants, with no language restrictions and across all age groups. All relevant articles were accessed in full text. Read More

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December 2021

Clinical Profile of Melkersson-Rosenthal Syndrome/Orofacial Granulomatosis: A Review of 51 Patients.

J Cutan Med Surg 2021 Jul-Aug;25(4):390-396. Epub 2021 Feb 11.

Department of Dermatology, Medical School, Av. Dr. Eneas de Carvalho Aguiar 255, Brazil.

Background: Melkersson-Rosenthal syndrome (MRS) is a rare disease characterized by the triad of granulomatous cheilitis, fissured tongue, and facial paralysis. Publications concerning large series are rare in the literature.

Objectives: To describe the clinical and histopathological characteristics of patients with complete and oligosymptomatic forms of MRS. Read More

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December 2021

Presentation of Bilateral Facial Paralysis in Melkersson-Rosenthal Syndrome.

Case Rep Neurol Med 2021 6;2021:6646115. Epub 2021 Jan 6.

Duke University, Durham, NC, USA.

. Melkersson-Rosenthal syndrome (MRS) is a neuromucocutaneous disorder characterized by the following classic symptom triad: peripheral facial paralysis, orofacial edema, and scrotal or fissured tongue. It is rare, and since most of the patients are oligo- or monosymptomatic, it makes it difficult to diagnose. Read More

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January 2021

An Intriguing Case of Ectopic Benign Migratory Glossitis Resembling Secondary Syphilis: A Case Report.

Case Rep Dermatol 2020 Sep-Dec;12(3):262-265. Epub 2020 Nov 26.

Department of Stomatology, Oral Medicine Clinic, School of Dentistry, University of São Paulo, São Paulo, Brazil.

Oral mucosal lesions presenting as erythematous patches usually pose difficulties for a clinical diagnosis. They elicit an array of differential diagnosis that mainly includes oral candidosis, contact mucosal reaction, oral lichenoid lesion, oral psoriasiform, autoimmune disease, and, not to forget, secondary syphilis. In this present case, all those above-mentioned possibilities were ruled out, while secondary syphilis stood as the main diagnosis. Read More

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November 2020

Melkersson-Rosenthal syndrome misdiagnosed as recurrent Bell's palsy: a case report and review of literature.

Allergy Asthma Clin Immunol 2021 Jan 9;17(1). Epub 2021 Jan 9.

Department of Neurology, School of Medicine, College of Health Sciences, Addis Ababa University, P.O. Box 41690, Addis Ababa, Ethiopia.

Background: Melkersson-Rosenthal syndrome (MRS) is a rare neuro-mucocutaneous disorder of unknown cause, clinically characterized by a triad of recurrent facial palsy, orofacial swelling, and fissured tongue. It is frequently seen in females in their second and third decades of life. MRS is diagnosed based on clinical features and it is rarely possible to observe all the classical triad symptoms at the same time. Read More

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January 2021

Melkersson-Rosenthal Syndrome: a Case Report of the Classic Triad.

J Dent (Shiraz) 2020 Dec;21(4):335-337

Resident, Dept. of Oral Medicine, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.

Melkersson-Rosenthal syndrome (MRS) is a rare neurological condition that includes a triad of symptoms including recurring facial paralysis, orofacial swelling, and fissured tongue. The diagnosis and treatment of this syndrome is difficult since the classic triad is rarely possible to see in its complete form. The etiology of MRS is unknown, but it is thought to be caused by various factors such as infections, genetic predisposition, immune deficiency, food intolerance, and stress. Read More

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December 2020

Prevalence of oral mucosal normal variations and lesions in a middle-aged population: a Northern Finland Birth Cohort 1966 study.

BMC Oral Health 2020 12 9;20(1):357. Epub 2020 Dec 9.

Cancer and Translational Medicine Research Unit, Faculty of Medicine, University of Oulu, P.O. Box 5281, 90014, Oulu, Finland.

Background: In this cross-sectional study we investigated the oral mucosal changes in a middle-aged Finnish population. We analyzed the prevalence of potentially malignant disorders and the influence of smoking, snuff and alcohol use on the mucosal changes.

Methods: Of the 12,068 members of the NFBC 1966, a total of 1961 participants (16. Read More

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December 2020

A case of Melkersson-Rosenthal syndrome with endocrine disorders: Extraordinary efficiency of hydroxychloroquine and mechanism hypothesis.

Eur J Neurol 2021 03 14;28(3):928-933. Epub 2020 Dec 14.

State Key Laboratory of Oral Diseases, Department of Oral Medicine, West China Hospital of Stomatology, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, China.

Background And Purpose: Melkersson-Rosenthal syndrome (MRS) is a rare neuro-mucocutaneous disease. In addition to the traditional clinical triad, there is also a diversity of clinical signs, and it may be related to other systemic diseases.

Methods: In the present study, we report a case of MRS with endocrine disorders that exhibits extraordinary therapeutic efficiency by using hydroxychloroquine (HCQ), explore whether there is an internal connection between MRS and endocrine disorders, and discuss the mechanism of the therapeutic efficiency of using HCQ. Read More

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Uncommon Coronary Abnormalities in a Patient with Discoid Lupus Erythematosus.

Int J Angiol 2020 Dec 12;29(4):260-262. Epub 2019 Sep 12.

Department of Internal Medicine, Kettering Medical Center, Kettering, Ohio.

A 43-year-old male presented with shortness of breath and palpitations. Physical examination was significant for skin lichenification, an erythematous maculopapular rash with annular plaques, a fissured tongue, and digital clubbing. Electrocardiogram captured a supraventricular tachycardia and right bundle branch block. Read More

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December 2020

Oral mucosal lesions in psoriatic patients based on disease severity and treatment approach.

J Oral Pathol Med 2020 Sep 1;49(8):822-828. Epub 2020 Sep 1.

Department of Gerodontology and Oral Pathology, Poznan University of Medical Sciences, Poznan, Poland.

Background: This observational case-control study was designed to investigate the frequency of oral lesions in psoriatic patients and to identify an association between mucosal involvement, the severity of the disease, and a form of treatment.

Methods: One hundred twenty-seven patients diagnosed with psoriasis were enrolled in this study from November 2018 to September 2019. The oral mucosa evaluation was based on the clinical appearance, location, and morphology of the lesions. Read More

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September 2020