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    1 OF 8

    Oral mucosal lesions in a Chilean elderly population: A retrospective study with a systematic review from thirteen countries.
    J Clin Exp Dent 2017 Feb 1;9(2):e276-e283. Epub 2017 Feb 1.
    Gerontology Program, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
    Background: The oral examination is an essential part of the multidisciplinary medical care in elderly people. Oral mucosal lesions and normal variations of oral anatomy (OMLs) are very common in this people, but few studies have examined the frequency and prevalence of these conditions worldwide and less in Chile. The aim of this research was to evaluate the frequency of OMLs in a Chilean elderly population. Read More

    Investigation of the clinical features of geographic tongue: unveiling its relationship with oral psoriasis.
    Int J Dermatol 2017 Feb 10. Epub 2017 Feb 10.
    Postgraduate Program in Pathology, School of Medicine, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.
    Background: Few studies have examined the clinical features of geographic tongue (GT), an inflammatory lesion, making diagnosis and the investigation of oral psoriasis difficult.

    Purpose: To investigate the clinical features of GT to facilitate its identification and understand its relationship with psoriasis.

    Methods: A total of 96 participants diagnosed with GT underwent stomatological and dermatological examinations. Read More

    Melkersson-Rosenthal Syndrome: A Case Report With a Psychosomatic Perspective.
    Adv Mind Body Med 2017 Winter;31(1):14-17
    Context • The Melkersson-Rosenthal syndrome (MRS) is a rare condition characterized by a triad of symptoms: (1) recurrent and/or persistent orofacial swelling, (2) recurrent facial paralysis, and (3) a fissured tongue. Although various contributing factors have been suggested, the etiology and mechanisms of the syndrome have not been fully elucidated. Objective • The aim of the current study was to examine for the first time some psychosomatic aspects of the syndrome and to evaluate the benefits of a brief psychotherapeutic process in which the research team worked to reintegrate the complex bio-psycho-social functioning of the patient. Read More

    Oral Manifestations of Job's Syndrome in a Paediatric Dental Patient - A Case Report.
    J Clin Diagn Res 2016 Nov 1;10(11):ZD04-ZD05. Epub 2016 Nov 1.
    Professor and Head, Department of Pedodontics, Government Dental College , Calicut, Kerala, India .
    Job's syndrome or Hyperimmunoglobulin E Syndrome (HIES) is a rare primary immunodeficiency with marked increase in serum immunoglobulin E (IgE) levels and eczematous dermatitis. Individuals with HIES share characteristic facial features, with many oral manifestations like retained deciduous teeth, fissured tongue, missing permanent tooth buds, recurrent oral candidiasis, oral mucosal and gingival lesions. Two forms of disease have been identified based on the defective gene as autosomal dominant form and autosomal recessive form. Read More

    An unusual case of folliculitis spinulosa decalvans.
    Cutis 2016 Sep;98(3):175-178
    Department of Dermatology, The First Hospital Affiliated to Soochow University, Suzhou, Jiangsu Province, China.
    We report the case of a 24-year-old man who presented with pustules, atrophic scars, and alopecia on the scalp, along with follicular keratotic papules on the cheeks, chest, abdomen, back, lateral upper arms, thighs, and axillae, of 6 years' duration. A diagnosis of folliculitis spinulosa decalvans (FSD) was made based on the clinical manifestation and histopathological findings. Dental examination also revealed dental anomalies and a fissured tongue, which are not known to be related to FSD. Read More

    Host and clinical aspects in patients with benign migratory glossitis.
    Arch Oral Biol 2017 Jan 26;73:259-268. Epub 2016 Oct 26.
    Pontifícia Universidade Católica do Paraná, Curitiba, PR, Brazil.
    Objective: Investigate the association of clinical, cytological and genetic characteristics with benign migratory glossitis (BMG).

    Study Design: Sample consisted of 175 patients, 44 with BMG and 131 control patients. Clinical examination and DMFT index were assessed. Read More

    Frequency of fissured tongue (lingua plicata) as a function of age.
    Swiss Dent J 2016 ;126(10):886-897
    Department of Oral Surgery, Oral Radiology and Oral Medicine and Center of Dental Traumatology, University Center for Dental Medicine Basel, University of Basel, Switzerland.
    Fissured tongue (lingua plicata; LP) is a mostly asymptomatic condition characterized by grooves and fissures of varying depth on the dorsal surface of the tongue. Most reports in the literature indicate a prevalence of 10–20%, although there is marked variation. On the basis of 1,000 patients (n=465 males, n=535 females), this study examined the association between LP and age as well as further influencing factors. Read More

    [A patient with Melkersson-Rosenthal syndrome].
    Ned Tijdschr Geneeskd 2016 ;160(0):D427
    Leids Universitair Medisch Centrum, afd. Neurologie, Leiden.
    Background: Melkersson-Rosenthal syndrome (MRS) is a relatively rare syndrome characterised by the clinical triad of persisting or recurrent facial oedema, recurrent peripheral facial palsy, and a fissured tongue.

    Case Description: A 30-year-old male patient presented with a left peripheral facial palsy spreading to the right side of the face. The left-sided facial paralysis recurred twice after initial recovery. Read More

    Treatment of Symptomatic Geographic Tongue with Triamcinolone Acetonide Alone and in Combination with Retinoic Acid: A Randomized Clinical Trial.
    J Dent (Tehran) 2016 Jan;13(1):23-8
    Statistical Consultant, Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
    Objectives: Geographic tongue or migratory glossitis is an inflammatory disorder with unknown etiology. Considering the accompanied burning pain, taste dysfunction, and lack of definite cure, it is important to treat this condition symptomatically. The objective of the current study was to compare the efficacy of a combination of 0. Read More

    Prevalence and distribution of oral mucosal non-malignant lesions in the western Sicilian population.
    Minerva Stomatol 2016 Aug;65(4):191-206
    Department of Surgical, Oncological and Stomatological Disciplines, University of Palermo, Palermo, Italy -
    Backgroung: The aim of the present study was to determine the prevalence of oral mucosal non-malignant lesions in the Sicilian population. In addition, we evaluated the association between each oral lesion and its risk factors.

    Methods: This study analyzed a total of 2539 consecutive patients, attending the Department of Surgical, Oncological and Stomatological Disciplines of Palermo University, who were examined for the presence of various oral lesions during the period from January 2012 and February 2015. Read More

    Diseases of the tongue.
    Clin Dermatol 2016 Jul-Aug;34(4):458-69. Epub 2016 Mar 8.
    Department of Dermatology, Mayo Clinic, Scottsdale, AZ.
    The tongue is a complex organ involved in speech and expression as well as in gustation, mastication, and deglutition. The oral cavity, along with the tongue, are sites of neoplasms, reactive processes, and infections, and may be a harbinger of systemic diseases. This review includes both common and rare diseases that occur on the tongue, including: vascular and lymphatic lesions (infantile hemangiomas and oral varices), reactive and inflammatory processes (hairy tongue, pigmented fungiform papillae of the tongue, benign migratory glossitis, and fissured tongue), infections (oral hairy leukoplakia, herpes simplex and varicella-zoster virus infections, human papillomavirus, and candidiasis), premalignant lesions (leukoplakia and erythroplakia), malignant lesions (squamous cell carcinoma, Kaposi sarcoma, and lymphoproliferative diseases), and signs of systemic disease (nutritional deficiency and systemic amyloidosis). Read More

    Prevalence and subjective knowledge of tongue lesions in an Indian population.
    J Oral Biol Craniofac Res 2016 May-Aug;6(2):124-8. Epub 2016 Jan 13.
    Ex-Senior Lecturer, Department of Oral Medicine and Radiology, Haldia Institute of Dental Sciences and Research, Haldia, West Bengal, India.
    Aim: The current study was designed to determine prevalence of various tongue lesions and their association with age, gender, systemic illness, deleterious habits, and distribution over the surfaces of tongue. It also explored the awareness and knowledge of subjects in relation to presence of tongue lesions, etiological factor, symptoms, and treatment received if any.

    Methods: The present study was conducted on 1360 randomly selected dental outpatients from 1/10/2013 to 30/09/2014. Read More

    A FURTHER PATIENT OF PURE 15q DELETION: CLINICAL AND MOLECULAR CYTOGENETIC FINDINGS.
    Genet Couns 2016 ;27(1):1-8
    A deletion of the distal long arm of chromosome 15 is generally reported with the formation of ring chromosome 15, whereas an isolated 15q deletion is rarely described. Here we report an 11 year-old girl, from non-consanguineous parents, who was referred to the Pediatric Genetics Department with growth retardation and multiple congenital abnormalities. In her medical history, she had a cleft palate, hip dislocation and crossed renal ectopia. Read More

    Recurrent Facial Palsy and Electrophysiological Findings in Oligosymptomatic Melkersson Rosenthal Syndrome.
    Indian J Pediatr 2016 Oct 11;83(10):1188-90. Epub 2016 May 11.
    Unit of Pediatric Neurology and Neurodevelopment, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.
    Melkersson Rosenthal Syndrome is a rare neuro-mucocutaneous disorder characterized by the classic triad of facial swelling, recurrent facial nerve palsy and fissured tongue. The clinical course is usually progressive, and etiology is unknown. The authors describe oligosymptomatic Melkersson Rosenthal Syndrome in a young girl presenting sequentially with recurrent, metachronous facial nerve palsy and hemifacial swelling in early childhood followed by fissuring in the tongue in late-childhood. Read More

    Prevalence of oro-dental anomalies among schoolchildren in Sana'a city, Yemen.
    East Mediterr Health J 2016 Apr 19;22(1):33-8. Epub 2016 Apr 19.
    Department of Preventive Dental Sciences, Al-Farabi College, Riyadh, Saudi Arabia.
    Practitioners and policy-makers need information about the relative frequency of dental anomalies among children in their region. This study investigated the prevalence of different oral anomalies among schoolchildren in Sana'a city, Yemen. A sample of 1000 private and public schoolchildren aged 4-12 years were examined by the same examiner using disposable tongue blades. Read More

    Melkersson-Rosenthal Syndrome with Genitalia Involved in a 12-Year-Old Boy.
    Ann Dermatol 2016 Apr 31;28(2):232-6. Epub 2016 Mar 31.
    Department of Dermatology, Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
    Melkersson-Rosenthal syndrome (MRS) is an uncommon granulomatous disease characterized by the triad of relapsing facial paralysis, orofacial swelling, and fissured tongue. Genital swelling in MRS is rarely reported. We presented the first case of complete MRS with genital swelling in a child. Read More

    Dental management of Rapp-Hodgkin syndrome associated with oral cleft and hypodontia.
    J Indian Soc Pedod Prev Dent 2016 Apr-Jun;34(2):192-5
    Department of Pedodontics and Preventive Children Dentistry, Sri Ramakrishna Dental College and Hospital, Coimbatore, Tamil Nadu, India.
    Rapp-Hodgkin syndrome (RHS) is a rare type of autosomal dominant disorder characterized by association of ectodermal dysplasia (ED) with cleft lip/palate. The main features include dry, brittle hair with alopecia in adulthood, dental anomalies (hypodontia, microdontia with delayed eruption, fissured tongue, and retruded maxilla), hypohidrosis, dysplastic nails, and clefting. Palmar-plantar keratoderma is seen frequently. Read More

    [Chronic or recurrent ulceration of the tongue].
    Ann Dermatol Venereol 2016 Apr 30;143(4):297-308; quiz 295-6, 309-10. Epub 2016 Mar 30.
    Dermatologie, consultation pluridisciplinaire de pathologies de la muqueuse buccale, institut Claudius-Regaud, institut universitaire du cancer Toulouse Oncopole, 1, avenue Irène-Joliot-Curie, 31059 Toulouse cedex 9, France.

    Histopathological Features of Orofacial Granulomatosis.
    Am J Dermatopathol 2016 Mar;38(3):194-200
    Departments of *Dermatology, and †Pathology, Hospital Universitari de Bellvitge, IDIBELL, Universitat de Barcelona, Barcelona, Spain.
    Orofacial granulomatosis (OFG) is characterized by granulomatous inflammation in the orofacial region. Although several series have been reported, biopsy has not been performed in all cases and the histopathological features have not been extensively evaluated. Our purpose was to analyze the histopathological features of our patients with OFG. Read More

    A rare thymoma case with seven paraneoplastic syndromes.
    Int J Clin Exp Med 2015 15;8(10):19517-23. Epub 2015 Oct 15.
    Department of Neurology, Shanghai Tenth People Hospital, Tongji University, School of Medicine China.
    Thymoma is a kind of epithelial tumor of the thymus which about 30-50% patients accompanied by paraneoplastic disorders. However, the coexistence of seven symptoms in an individual is rare. This report represented a patient, diagnosed of thymoma, with myasthenia gravis, erythema multiforme, plasma cell cheilitis, recurrent oral ulcer, vitiligo, Raynaud's phenomenon and fissured tongue. Read More

    Melkersson-Rosenthal syndrome as an early manifestation of mixed connective tissue disease.
    Eur J Med Res 2015 Dec 23;20:100. Epub 2015 Dec 23.
    Speciality Hospital in Gorlice, ul. Wegierska 21, 38-300, Gorlice, Poland.
    Purpose Of Review: We aim to illustrate the potential viability of MCTD as an underlying aetiology of Melkersson-Rosenthal syndrome. The case is probably the first description available in the literature of the Melkersson-Rosenthal as an early manifestation of mixed connective tissue disease.

    Recent Findings: The Melkersson-Rosenthal syndrome consists of a triad of recurrent lip and/or face swelling, fissured tongue, and intermittent facial palsy. Read More

    Melkersson-Rosenthal Syndrome with Orofacial Swelling and Recurrent Lower Motor Neuron Facial Nerve Palsy: A Case Report and Review of the Literature.
    Case Rep Otolaryngol 2015 9;2015:214946. Epub 2015 Nov 9.
    Warrawong Accident and Medical Center, King Street, Westfield, Warrawong, NSW 2502, Australia.
    Melkersson-Rosenthal Syndrome (MRS) is a rare otoneurologic condition, which is poorly understood and often underdiagnosed. Etiology and incidence are unclear, although infectious, inflammatory, and genetic causes have been implicated. Recurrent facial nerve palsy, facial swelling, and fissured tongue are the symptoms and signs of this condition. Read More

    Oral manifestations of asthmatic patients.
    J Pak Med Assoc 2015 Nov;65(11):1226-7
    Department of Oral pathology, Faculty of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.
    The effect of asthma on oral health is the subject of debate among dental practitioners. The current study was planned to investigate the oral manifestations of asthmatics compared to healthy subjects. The study group composed of 100 asthmatics and 100 age-matched healthy controls. Read More

    Newer Classification System for Fissured Tongue: An Epidemiological Approach.
    J Trop Med 2015 20;2015:262079. Epub 2015 Sep 20.
    Department of Oral Medicine and Radiology, SIBAR Institute of Dental Sciences, Guntur 522509, India.
    Introduction. Fissured tongue is a commonly encountered tongue disorder in dental practice. But there is a lack of data on different pattern, severity, and association of fissuring with various systemic disorders and other tongue anomalies. Read More

    Factors associated with geographic tongue and fissured tongue.
    Acta Odontol Scand 2016 18;74(3):210-6. Epub 2015 Sep 18.
    a Department of Oral Medicine and Pathology , Institute of Odontology, the Sahlgrenska Academy, University of Gothenburg , Sweden.
    Objectives: The primary objective of this study was to investigate the association of systemic diseases, use of medications, allergies and tobacco habits with geographic tongue (GT) and fissured tongue (FT) lesions. The secondary objectives were to evaluate the clinical characteristics of tongue lesions and to compare the overall results for referred and non-referred patients.

    Methodology: Non-referred patients with GT (GTgp; n = 130) and FT (FTgp; n = 62) were examined by general practitioners (gp) and compared to a control group without oral mucosal lesions (C; n = 1029). Read More

    Oral hygiene and oral flora evaluation in psychiatric patients in nursing homes in Turkey.
    Niger J Clin Pract 2015 Nov-Dec;18(6):751-6
    Department of Oral and Maxillofacial Radiology (Oral Diagnosis and Radiology), Faculty of Dentistry, Ondokuz Mayis University, Samsun, Turkey.
    Context: The World Health Organization has stated that psychiatric patients are a group of people who have oral and dental illnesses.

    Aims: The aims of this study were to document the oral hygiene of individuals with chronic psychiatric illness, to determine the extraoral and intraoral findings, to detect the dominant microorganisms in oral flora, and to inform clinicians of these findings.

    Settings And Design: The study included 100 patients (69 men and 31 women) with different psychiatric illnesses living in a nursing home. Read More

    Clinicopathological significance of Melkersson-Rosenthal syndrome.
    BMJ Case Rep 2015 Jul 31;2015. Epub 2015 Jul 31.
    Department of Pedodontics and Preventive Dentistry, Karnavati School of Dentistry, Gandhinagar, Gujarat, India.
    Melkersson-Rosenthal syndrome (MRS) classically shows a triad of orofacial swelling, fissured tongue and facial palsy, more commonly the oligosymptomatic form. The orofacial swelling is characterised by swollen reddish-brown non-pruritic lips and facial oedema. In one-third to one half of patients, fissured tongue is seen, which also aids in diagnosis. Read More

    Oral and salivary changes in patients with chronic kidney disease: A clinical and biochemical study.
    J Indian Soc Periodontol 2015 May-Jun;19(3):297-301
    Department of Periodontics, MNR Dental College and Hospital, Sangareddi, Telangana, India.
    Background: Both chronic kidney disease (CKD) and its treatment can affect a wide range of tissues and systems. It directly or indirectly affects flow, concentrations and composition of saliva. Hemodialysis can effectively minimize most of these complications to some extent. Read More

    Prevalence of Geographic tongue and Related Predisposing Factors in 7-18 Year-Old Students in Kermanshah, Iran 2014.
    Glob J Health Sci 2015 Feb 24;7(5):91-5. Epub 2015 Feb 24.
    Kermanshah University of Medical Sciences.
    Geographic tongue is a benign lesion at the dorsum and margins of the tongue that sometimes causes pain and burning sensation. This lesion is characterized by an erythematous area with white or yellow folded edges. The predisposing factors of this lesion include heredity, allergies, psoriasis, stress, fissured tongue and consumption of some foods. Read More

    Lip and oral lesions in children with Down syndrome. A controlled study.
    J Clin Exp Dent 2015 Apr 1;7(2):e284-8. Epub 2015 Apr 1.
    Assistant Professor, Department of Oral Maxillofacial Sciences, College of Dentistry, Taibah University.
    Background: Down syndrome (DS) is the most common chromosomal abnormality affecting numerous organs, including the orofacial region. The objective of the present study was to assess the prevalence of lip and oral soft tissue lesions, with particular emphasize on the incidence of fissured tongue, lip fissures and angular cheilitis, among individuals with DS in Yemen.

    Material And Methods: This controlled cross-sectional study included 50 children with DS (6-18 years), and 50 age-and gender-matched healthy controls. Read More

    Oral mucosal lesions in elderly dental patients in Sana'a, Yemen.
    J Int Soc Prev Community Dent 2015 May;5(Suppl 1):S12-9
    Department of Oral and Maxillofacial Sciences, Al-Farabi Colleges of Dentistry and Nursing, Riyadh, Kingdom of Saudi Arabia.
    Objectives: With aging, the oral mucosa becomes more susceptible to external stimuli. The aims of this study were to obtain baseline data on the prevalence of oral mucosal lesions (OMLs) in a population of elderly Yemeni patients and to investigate differences in the presentation of these findings in relation to age, gender, education level, and the wearing of dentures.

    Patients And Methods: The prevalence of OMLs was assessed by clinical examination of a sample of 310 elderly Yemeni patients aged 60 years and older. Read More

    Evaluation of the orofacial lesions in treated leprosy patients.
    J Oral Maxillofac Pathol 2014 Sep-Dec;18(3):386-9
    Department of Oral and Maxillofacial Pathology, Navodaya Dental College, Raichur, Karnataka, India.
    Background: Leprosy is primarily a disease of developmental countries. About 4 million people have or are disabled by leprosy. Eighty-six percent of leprosy patients reside in Southeast Asia and Brazil. Read More

    [Research progress on the risk factors of geographic tongue].
    Hua Xi Kou Qiang Yi Xue Za Zhi 2015 Feb;33(1):93-7
    Geographic tongue, also called benign migratory glossitis, is a common and superficial benign inflammatory disorder that affects the tongue epithelium. The majority of geographic tongue lesions typically manifest as irregular central erythematous patches. These lesions, which are caused by the loss of filiform papillae, are defined by an elevated whitish band-like border that can change location, size, and pattern over a period of time. Read More

    Oral manifestation in mentally challenged children.
    J Int Oral Health 2015 Feb;7(2):37-41
    Reader, Department of Periodontics, Mahe Institute of Dental Sciences and Hospital, Mahe, Kerala, India.
    Background: In general, mentally challenged children have higher rates poor oral hygiene, gingivitis and periodontitis than the general population. An investigation was undertaken to assess the oral manifestations of mentally challenged children in Chennai, India.

    Materials And Methods: The study group consisted of 150 children (70 Down syndrome patients and 80 cerebral palsy patients). Read More

    Oral mucosal lesions in older people: relation to salivary secretion, systemic diseases and medications.
    Oral Dis 2015 Sep 6;21(6):721-9. Epub 2015 Apr 6.
    Section of Oral Medicine, Clinical Oral Physiology, Oral Pathology and Anatomy, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
    Objectives: To determine the prevalence of oral mucosal lesions in a sample of older Danish people and to investigate their associations with age, gender, systemic diseases, medications, xerostomia and salivary secretion.

    Methods: A total of 668 community-dwelling individuals aged 65-95 years underwent a clinical examination, measurements of unstimulated and stimulated whole and labial salivary flow rates and an interview regarding xerostomia, general health, medication, tobacco and alcohol habits.

    Results: Seventy-five per cent of all participants and 70% of the non-medicated ones had one or more oral mucosal lesions. Read More

    Geographic tongue and fissured tongue in 348 patients with psoriasis: correlation with disease severity.
    ScientificWorldJournal 2015 19;2015:564326. Epub 2015 Jan 19.
    Hospital Universitário Antonio Pedro, Faculdade de Medicina, Departamento de Patologia, Universidade Federal Fluminense, Rua Marques de Parana 303, 4° Andar, 24033-900 Niteroi, Rio de Janeiro, RJ, Brazil.
    Geographic tongue (GT) and fissured tongue (FT) are the more frequent oral lesions in patients with psoriasis. The aims of this study were to compare the prevalence of GT/FT between psoriasis group (PG) and healthy controls (HC) and investigate the correlation between GT/FT and psoriasis severity using the PASI and age of psoriasis onset. Three hundred and forty-eight PG and 348 HC were selected. Read More

    Oral mucosal lesions and their association with tobacco use and qat chewing among Yemeni dental patients.
    J Clin Exp Dent 2014 Dec 1;6(5):e460-6. Epub 2014 Dec 1.
    Dental practitioner, Department of oral and dental surgery, Al-Kuwait teaching Hospital, Sana'a, Yemen.
    Objectives: This study aimed to assess the prevalence of oral mucosal lesions (OMLs) in patients attending outpatient dental clinics in Sana`a university, Yemen, and to evaluate the association of such lesions with age, gender, and oral habits.

    Materials And Methods: This cross-sectional study included 409 subjects (272 males, 137 females, age: 15-86 years). Detailed clinical examination was performed in accordance with international criteria. Read More

    Prevalence of oral lesions and measurement of salivary pH in the different trimesters of pregnancy.
    Singapore Med J 2015 Jan;56(1):53-7
    Sudha Rustagi College of Dental Sciences and Research, Kheri More, Bhopani, Piyush Heights, Sector 89, Faridabad, Haryana 121002, India.
    Introduction: Oral changes observed during pregnancy have been studied for many years, but their magnitude and frequency have not been stressed upon. This study was undertaken to assess the prevalence of oral lesions during different trimesters of pregnancy and their correlation with salivary pH change.

    Methods: The gingival, simplified oral hygiene, community periodontal and decayed-missing-filled teeth indices were used to assess a total of 120 pregnant women (40 in each trimester group) and 40 nonpregnant women (control group). Read More

    Dentofacial and cranial changes in down syndrome.
    Osong Public Health Res Perspect 2014 Dec 12;5(6):339-44. Epub 2014 Nov 12.
    Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
    Objectives: This study aimed to determine the prevalence of certain oral characteristics usually associated with Down syndrome and to determine the oral health status of these patients.

    Methods: The cross-sectional study was conducted among patients attending a special education program at Faculty of Dentistry, Jamia Millia Islamia, Delhi, India. The study design consisted of closed-ended questions on demographic characteristics (age, sex, and education and income of parents), dietary habits, and oral hygiene habits. Read More

    Normal variations of oral anatomy and common oral soft tissue lesions: evaluation and management.
    Med Clin North Am 2014 Nov 22;98(6):1281-98. Epub 2014 Sep 22.
    Oral Medicine Clinical Services, Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, 240 South 40th Street, Philadelphia, PA 19104, USA. Electronic address:
    Examination of the oral cavity can provide significant diagnostic information regarding the general health of the patient. The oral cavity is affected by a multitude of pathologic conditions of variable cause and significance; however, there are numerous normal variations of oral soft tissue structures that may resemble a pathologic state. Understanding these variations assists practitioners to discriminate between normal versus abnormal findings and determine the appropriate course of management, if necessary. Read More

    Periodontal disease: an oral manifestation of psoriasis or an occasional finding?
    Drug Dev Res 2014 Nov;75 Suppl 1:S46-9
    Clinic of Dermatology, Polytechnic University of Marche Region, Ancona, 60126, Italy.
    Even if the existence of oral psoriasis has been suggested, it is still a debated issue. Indeed, oral inflammatory diseases may histologically resemble psoriasis-related oral lesions. However, an increased prevalence of fissured tongue and geographic tongue has been associated with psoriatic patients, being a transitory and permanent lesion, respectively. Read More

    Prevalence and distribution of oral mucosal lesions: a cross-sectional study in Shanghai, China.
    J Oral Pathol Med 2015 Aug 22;44(7):490-4. Epub 2014 Sep 22.
    Department of Oral Mucosal Diseases, Shanghai Key Laboratory of Stomatology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
    Background: An epidemiological study on the oral mucosal lesions (OMLs) in general population from China was scarce. The objective of this study was to investigate the prevalence and distribution of OMLs in Shanghai, China and to evaluate their association with demographic factors and smoking/drinking habits based on a large scaled population on a wide spectrum.

    Methods: In this population-based cross-sectional study, 11054 community-dwelling individuals (M/F: 5140/5914; age range, 1-96 years) were randomly selected and examined according to WHO criteria. Read More

    [Analysis of tongue figure features in 990 cases of sexually transmitted and intravenous drug use spread HIV infected population in Xinjiang].
    Zhongguo Zhong Xi Yi Jie He Za Zhi 2014 Jul;34(7):816-8
    Objective: To investigate the tongue manifestation features of sexually transmitted and intravenous drug use spread HIV infected population in Xinjiang.

    Methods: Recruited were 990 HIV infected subjects in Xinjiang from May 2011 to March 2012, who were assigned to the intravenous drug use spread HIV infected (498 cases) and the sexually transmitted (492 cases). By using tongue figure shoot combined with analyses of experts, tongue manifestations were analyzed and compared between the sexually transmitted and the intravenous drug use spread from four aspects, i. Read More

    Melkersson-Rosenthal syndrome: a retrospective study of 44 patients.
    Acta Otolaryngol 2014 Sep 25;134(9):977-81. Epub 2014 Jun 25.
    The 9th Clinical Medical College, Peking University , Beijing.
    Conclusion: When patients with recurrent facial paralysis are encountered, otolaryngologists should check for fissured tongue, and question those patients about orofacial edema, minor symptoms, and family history. Histologic evidence is not necessary for the diagnosis of Melkersson-Rosenthal syndrome (MRS), while coronary high-resolution CT (HRCT) reconstruction of temporal bone and food allergen detection may be beneficial. Prophylactic decompression of the facial nerve for patients with appropriate electrophysiological indication may prevent further facial palsy attacks. Read More

    Melkersson-Rosenthal syndrome: a facial nerve center perspective.
    J Plast Reconstr Aesthet Surg 2014 Aug 2;67(8):1050-4. Epub 2014 May 2.
    Facial Nerve Center, Department of Otolaryngology, University of Pittsburgh Medical Center, USA. Electronic address:
    Objectives: Melkersson-Rosenthal syndrome (MRS) is a rare neuro-mucocutaneous granulomatous disorder of unknown etiology, characterized by the triad of facial palsy, lingua plicata (fissured tongue), and orofacial edema. Few articles in the literature report series with more than 20 patients or focus on the facial nerve dominant presentation of MRS.

    Methods: We performed a retrospective review of the patients diagnosed with MRS at a university-based Facial Nerve Center. Read More

    Association between the organoleptic scores, oral condition and salivary β-galactosidases in children affected by halitosis.
    Int J Dent Hyg 2014 Aug 28;12(3):213-8. Epub 2014 May 28.
    Department of Medical, Oral and Biotechnologicalical Sciences, University of Chieti, Chieti, Italy.
    Objectives: The goal of this work is to evaluate the association between organoleptic scores, oral condition and salivary β-galactosidases, to facilitate the differential diagnosis of halitosis in children.

    Methods: Fifty systemically healthy children with a primary complaint of oral malodour were included in this cross-sectional study. The organoleptic evaluation was carried out by two judges, evaluating the intensity of malodour of the air exhaled 5 s through the mouth of the patients, at a distance of approximately 10 cm from their noses; the level of salivary β-galactosidases was quantified spectrophotometrically after a chromatic reaction between a salivary sample of each patient and a specific chromatic substrate of the enzyme. Read More

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