711 results match your criteria First-Degree Atrioventricular Block


Pacemaker programming in patients with first-degree AV-block: Programming pattern and possible consequences.

Health Sci Rep 2018 Jun 9;1(6):e39. Epub 2018 May 9.

Clinical Cardiac Electrophysiology Duke University Medical Center Durham NC USA.

Background: The optimal way of pacing in patients with an indication for pacing and concomitant first-degree atrioventricular (AV)-block is not known, and consequently, firm guidelines on this topic are lacking. This study explored the current pacemaker programming pattern in patients with first-degree AV-block who have a dual chamber pacemaker without cardiac resynchronization.

Methods: The study was a retrospective chart review conducted at Duke University Hospital. Read More

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http://dx.doi.org/10.1002/hsr2.39DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6266422PMC

Occurrence of significant long PR intervals in patients implanted for sinus node dysfunction and monitored with SafeR™: The PRECISE study.

Arch Cardiovasc Dis 2018 Dec 26. Epub 2018 Dec 26.

Henri Mondor hospital, 94101 Créteil, France.

Background: Long PR intervals may increase cardiovascular complications, including atrial fibrillation. In pacemakers, the SafeR™ mode monitors PR intervals, switching from AAI to DDD when criteria for atrioventricular block are met.

Aims: The PRECISE study evaluated the incidence and predictors of long PR intervals and their association with incident atrial fibrillation after 1 year in patients implanted for sinus node dysfunction and free from significant conduction disorders at baseline. Read More

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http://dx.doi.org/10.1016/j.acvd.2018.09.005DOI Listing
December 2018
1 Read

Cisplatin-induced cardiotoxicity with midrange ejection fraction: A case report and review of the literature.

Medicine (Baltimore) 2018 Dec;97(52):e13807

Department of Cardiology, Peking Union Medical College Hospital, Beijing, China.

Rationale: Cisplatin monotherapy-induced cardiotoxicity is rare, and the prevalence remains unknown. It's extremely important to stop cisplatin when cardiotoxicity is considered.

Patient Concerns: A 53-year-old woman developed cervical cancer. Read More

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http://dx.doi.org/10.1097/MD.0000000000013807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314747PMC
December 2018
1 Read

Prognostic Significance of PR Interval Prolongation in Adult Patients With Total Correction of Tetralogy of Fallot.

Circ Arrhythm Electrophysiol 2018 Nov;11(11):e006234

Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan (Y.K., K. Fukuda, M.N., Y.H., K. Fukasawa, T.C., K.M., S.T., H.S.).

Background: Several studies have demonstrated the importance of mechanoelectrical interaction in patients with surgically corrected tetralogy of Fallot. However, the significance of atrioventricular conduction disturbance, that is PR interval prolongation, on adverse cardiac events in those patients remains to be elucidated.

Methods: We examined electrocardiograms at baseline and their temporal change in a total of 176 patients with repaired tetralogy of Fallot (49% men; median age, 17. Read More

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http://dx.doi.org/10.1161/CIRCEP.118.006234DOI Listing
November 2018
1 Read

Dysrhythmias in patients with a complete atrioventricular septal defect: From surgery to early adulthood.

Congenit Heart Dis 2018 Nov 28. Epub 2018 Nov 28.

Department of Cardiothoracic Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands.

Objective: Outcomes after surgical repair of complete atrioventricular septal defect (cAVSD) have improved. With advancing age, the risk of development of dysrhythmias may increase. The aims of this study were to (1) examine development of sinus node dysfunction (SND), atrial and ventricular tachyarrhythmias, and (2) study progression of atrioventricular conduction abnormalities in young adult patients with repaired cAVSD. Read More

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http://dx.doi.org/10.1111/chd.12724DOI Listing
November 2018
1 Read

Syncope due to complete atrioventricular block and treatment with a transient pacemaker in acute rheumatic fever.

Turk Pediatri Ars 2018 Sep 1;53(3):197-199. Epub 2018 Sep 1.

Department of Pediatric Cardiology, Necip Fazıl City Hospital, Kahramanmaraş, Turkey.

Various rhythm and connection disorders can be seen in the acute phase of acute rheumatic fever. First degree atrioventricular block, one of the minor signs of acute rheumatic fever, is the most common connection disturbance in this disease. Complete atrioventricular block, which seriously affects the conduction pathways, is rare in the literature. Read More

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http://dx.doi.org/10.5152/TurkPediatriArs.2018.4014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239074PMC
September 2018
1 Read

Pulsed Doppler fetal atrioventricular interval measurement: Assessment of a new image scoring method.

J Gynecol Obstet Hum Reprod 2018 Nov 8. Epub 2018 Nov 8.

Department of Obstetrics and Gynaecology, Hôpital Antoine Béclère, APHP, University Paris Sud, Clamart, France. Electronic address:

Objectives: We propose an image scoring method to improve the quality and the reproducibility of measurement of the AV interval before establishing reference tables of the measurements and studies on the prevention and treatment of first-degree AV block especially if the first child has been diagnosed AV block.

Method: Prospective study from May 2015 to June 2016. Sonographers were asked to measure AV interval with pulsed Doppler in a five-chamber view in standard second-trimester screening before and after having received our image scoring method. Read More

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http://dx.doi.org/10.1016/j.jogoh.2018.10.022DOI Listing
November 2018
10 Reads

Lithium intoxication presenting as altered consciousness and arrhythmia with cardiogenic shock: A case report.

Medicine (Baltimore) 2018 Nov;97(45):e13129

Department of Emergency Medicine, Kaohsiung Medical University Hospital.

Rationale: Lithium has been used to treat bipolar disorder. Lithium has a narrow therapeutic index, with a therapeutic level between 0.6 and 1. Read More

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http://Insights.ovid.com/crossref?an=00005792-201811090-0005
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http://dx.doi.org/10.1097/MD.0000000000013129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250446PMC
November 2018
11 Reads

The Incremental Benefit of Color Tissue Doppler in Fetal Arrhythmia Assessment.

J Am Soc Echocardiogr 2019 Jan 16;32(1):145-156. Epub 2018 Oct 16.

Fetal and Neonatal Cardiology Program, Department of Pediatrics, Division of Cardiology, Women's & Children's Health Research Institute, University of Alberta, Stollery Children's Hospital, Edmonton, Alberta, Canada. Electronic address:

Background: Accurate fetal arrhythmia (FA) diagnosis is key for effective management. Currently, FA assessment relies on standard echocardiography-based techniques (M mode and spectral Doppler), which require adequate fetal position and cursor alignment to define temporal relationships of mechanical events. Few data exist on the application of color Doppler tissue imaging (c-DTI) in FA assessment. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08947317183044
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http://dx.doi.org/10.1016/j.echo.2018.08.009DOI Listing
January 2019
9 Reads

Woman with recurrent vomiting.

Emerg Med J 2018 Nov;35(11):691

Emergency Department, Department of Emergency and Critical Care Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.

Clinical Introduction: A 69-year-old woman presented to the ED with a chief complaint of recurrent vomiting for 3 weeks. She was afebrile, blood pressure was 100/67 mm Hg, HR was 114/min, RR was 19/min and oxygen saturation was 98%. On physical examination, she had mild epigastric tenderness without guarding. Read More

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http://dx.doi.org/10.1136/emermed-2018-207554DOI Listing
November 2018
1 Read

Home Monitoring for Fetal Heart Rhythm During Anti-Ro Pregnancies.

J Am Coll Cardiol 2018 Oct;72(16):1940-1951

Division of Cardiology, Department of Pediatrics, Hospital for Sick Children, Toronto, Canada.

Background: Fetal atrioventricular block (AVB) occurs in 2% to 4% of anti-Ro antibody-positive pregnancies and can develop in <24 h. Only rarely has standard fetal heart rate surveillance detected AVB in time for effective treatment.

Objectives: Outcome of anti-Ro pregnancies was surveilled with twice-daily home fetal heart rate and rhythm monitoring (FHRM) and surveillance echocardiography. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07351097183694
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http://dx.doi.org/10.1016/j.jacc.2018.07.076DOI Listing
October 2018
18 Reads

A Rare Case of Second Degree Mobitz Type II AV Block Associated with Cocaine Use.

Am J Med Case Rep 2018 21;6(7):146-148. Epub 2018 Aug 21.

Department of Internal Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

Cocaine is a commonly abused illicit drug in the United States. The complex effects of cocaine on the conduction system of the human heart has not been completely understood. Cocaine acts as a sympathomimetic by inhibition of reuptake of neuronal catecholamines, leading mostly to tachyarrhythmias on presentation. Read More

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http://pubs.sciepub.com/ajmcr/6/7/7/index.html
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http://dx.doi.org/10.12691/ajmcr-6-7-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173318PMC
August 2018
2 Reads

[Bachmann bundle pacing].

Herz 2018 Nov;43(7):584-595

Klinik für Innere Medizin - Kardiologie, Diabetologie & Nephrologie, Evangelisches Klinikum Bethel, Burgsteig 13, 33617, Bielefeld, Deutschland.

In pacemaker and ICD therapy, atrial leads are usually implanted in the right atrial appendage (RAA). This is easy but associated with a risk of negative hemodynamic and electrophysiological effects. Atrial depolarization, atrial contraction, and atrioventricular conduction can be delayed and desynchronized by RAA pacing leading to atrial fibrillation, pacing-induced long first-degree AV block, right ventricular pacing and the development of heart failure. Read More

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http://dx.doi.org/10.1007/s00059-018-4755-6DOI Listing
November 2018
10 Reads

Association between decreasing estimated glomerular filtration rate and risk of cardiac conduction defects in patients with type 2 diabetes.

Diabetes Metab 2018 12 5;44(6):473-481. Epub 2018 Sep 5.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Piazzale Stefani, 1, 37126 Verona, Italy. Electronic address:

Aim: We aimed to assess the association between decreasing estimated glomerular filtration rate (eGFR) or abnormal albuminuria and the risk of certain cardiac conduction defects in patients with type 2 diabetes mellitus (T2DM).

Methods: We examined a hospital-based sample of 923 patients with T2DM discharged from our Division of Endocrinology over the years 2007-2014. Standard electrocardiograms (ECGs) were performed in all patients. Read More

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http://dx.doi.org/10.1016/j.diabet.2018.08.007DOI Listing
December 2018
2 Reads

"First-degree AV block-a benign entity?" Insertable cardiac monitor in patients with 1st-degree AV block reveals presence or progression to higher grade block or bradycardia requiring pacemaker implant.

J Interv Card Electrophysiol 2018 Aug 13;52(3):303-306. Epub 2018 Aug 13.

Cardiovascular Center, University Hospital Zurich, Zurich, Switzerland.

Background: First-degree AV block has in the past generally been considered a benign condition. A few recent studies have shown that 1st-degree AV block is associated with an increased risk for heart failure, pacemaker (IPG) implantation, and death. We investigated the outcomes of patients who received an insertable cardiac monitor (ICM) (Medtronic Reveal XT®) within the scope of the INSIGHT XT study and had 1st-degree AV block at baseline. Read More

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http://dx.doi.org/10.1007/s10840-018-0439-7DOI Listing
August 2018
2 Reads

Lyme Carditis: A Case Report and Review of Management.

Hosp Pharm 2018 Jul 2;53(4):263-265. Epub 2018 Jan 2.

University of Pittsburgh Medical Center Mercy, PA, USA.

A case report of a patient who presented with an acute onset, fluctuating atrioventricular (AV) block and was diagnosed with Lyme carditis is presented. A 55-year-old man with progressively worsening generalized malaise, flu-like symptoms, dyspnea on exertion, and near syncope was admitted with bradycardia (heart rate was between 20 and 30 beats per minute upon admission). He endorsed having several tick bites after which he developed erythema migrans on his arm and abdomen. Read More

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http://dx.doi.org/10.1177/0018578717749927DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050884PMC
July 2018
1 Read

Antidromic Atrioventricular Reentry Tachycardia with Wolff Parkinson White Syndrome: A Rare Beast.

Cureus 2018 May 17;10(5):e2642. Epub 2018 May 17.

Cardiology Department, Charleston Area Medical Center/west Virginia University.

Orthodromic atrioventricular reentrant tachycardia (AVRT) is the second-most-common form of supraventricular tachycardia (SVT) and is inducible in approximately 55% of individuals with Wolff Parkinson White (WPW) syndrome. Antidromic AVRT, where the accessory atrioventricular connection is used as the antegrade limb and the atrioventricular node serves as the retrograde limb of the circuit, has been clinically documented in less than 5% of patients with WPW syndrome and may be induced in less than 10% of these WPW cases in the electrophysiology laboratory. Left lateral pathways are considered more frequent and septal locations are less common when associated with antidromic AVRT. Read More

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http://dx.doi.org/10.7759/cureus.2642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050167PMC
May 2018
3 Reads

First-degree atrioventricular block on basal electrocardiogram predicts future arrhythmic events in patients with Brugada syndrome: a long-term follow-up study from the Veneto region of Northeastern Italy.

Europace 2018 Jul 6. Epub 2018 Jul 6.

Department of Cardiac, Thoracic, and Vascular Sciences, University of Padua Medical School, Via Giustiniani, 2 - 35128 Padova, Italy.

Aims: This study was designed to assess the prognostic value of clinical and electrocardiographic parameters in Brugada syndrome (BrS).

Methods And Results: The study population included 272 consecutive patients (82% males; mean age 43 ± 12 years), with either a spontaneous (n = 137, 50%) or drug-induced (n = 135, 50%) Type 1 Brugada electrocardiogram (ECG) pattern. The study combined endpoint included sudden cardiac death (SCD), cardiac arrest, and appropriate intervention of implantable cardioverter-defibrillator (ICD). Read More

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http://dx.doi.org/10.1093/europace/euy144DOI Listing
July 2018
2 Reads

Electrocardiographic abnormalities in Chagas disease in the general population: A systematic review and meta-analysis.

PLoS Negl Trop Dis 2018 06 13;12(6):e0006567. Epub 2018 Jun 13.

Department of Epidemiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.

Background: Chagas disease (CD) is a major public health concern in Latin America and a potentially serious emerging threat in non-endemic countries. Although the association between CD and cardiac abnormalities is widely reported, study design diversity, sample size and quality challenge the information, calling for its update and synthesis, which would be very useful and relevant for physicians in non-endemic countries where health care implications of CD are real and neglected. We performed to systematically review and meta-analyze population-based studies that compared prevalence of overall and specific ECG abnormalities between CD and non-CD participants in the general population. Read More

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https://dx.doi.org/10.1371/journal.pntd.0006567
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http://dx.doi.org/10.1371/journal.pntd.0006567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999094PMC
June 2018
9 Reads

Safety of ticagrelor in patients with baseline conduction abnormalities: A PLATO (Study of Platelet Inhibition and Patient Outcomes) analysis.

Am Heart J 2018 Aug 7;202:54-60. Epub 2018 May 7.

Cardiovascular Division, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address:

Background: Although bradyarrhythmias have been observed with ticagrelor and its use with advanced atrioventricular block is not recommended, questions arise regarding its use in patients with mild conduction abnormalities. The objectives were to compare rates of clinically relevant arrhythmias in relation to any mild baseline conduction abnormality in patients with acute coronary syndrome randomized to ticagrelor versus clopidogrel.

Methods: We included all subjects in the electrocardiographic (ECG) substudy of the Platelet Inhibition and Patient Outcomes trial, excluding those with missing baseline ECG or with a pacemaker at baseline (N = 15,460). Read More

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http://dx.doi.org/10.1016/j.ahj.2018.04.020DOI Listing
August 2018
11 Reads

Low-energy ablation of anteroseptal accessory pathways in two dogs.

J Vet Cardiol 2018 Aug 30;20(4):285-293. Epub 2018 May 30.

Department of Clinical Sciences, Cornell University, Ithaca, NY 14853, USA.

In humans, accessory pathways (APs) in an anteroseptal and midseptal position are often challenging to ablate because of their close proximity with the conduction pathways of the atrioventricular junction. The use of low-energy ablation techniques can be useful to reduce the risk of permanently damaging the atrioventricular node and the His bundle. This report describes the use of low-energy radiofrequency catheter ablation to successfully and permanently ablate anteroseptal APs in two dogs with orthodromic atrioventricular reciprocating tachycardia. Read More

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http://dx.doi.org/10.1016/j.jvc.2018.05.001DOI Listing
August 2018
1 Read

Chagasic cardiomyopathy and Pompe disease: case report.

Am J Cardiovasc Dis 2018 5;8(2):19-23. Epub 2018 Apr 5.

Hospital das Clínicas da UFPE, Department of Cardiology Brazil.

Background: Pompe disease is a lysosomal storage disease with an autosomal recessive inheritance characterized by an insufficient activity of the acid alpha-glucosidase enzyme. The incidence varies from 1:40000 to 1:200000 live births and cardiac involvement in adults is rare. Chagas disease is an infection caused by the protozoan Trypanosoma cruzi, in which one-third of the cases progress to the chronic form, and may lead to cardiac involvement, usually from the fifth decade of life onwards. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944812PMC
April 2018
3 Reads

Transient left anterior and septal fascicular blocks after self-expandable percutaneous transcatheter aortic valve implantation.

Ann Noninvasive Electrocardiol 2018 Apr 19:e12553. Epub 2018 Apr 19.

Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.

Transcatheter aortic valve implantation (TAVI) is indicated in severe symptomatic aortic stenosis, when there is intermediate-high surgical risk, or a condition considered inoperable, as in the case of "porcelain aorta" that could turn clamping or cannulation of the ascending aorta hazardous in open-heart surgery. Among the complications of this less invasive procedure, intraventricular conduction disorders subsequent to the procedure stand out. TAVI causes worsening of intraventricular dromotropic disorders in more than 75% of the cases, with the presence of preexisting right bundle branch block and first-degree atrioventricular block, deep prosthesis implant, male gender, size of the aortic annulus smaller than the prosthesis, and porcelain aorta being predictive of requirement for permanent pacemaker implant. Read More

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http://dx.doi.org/10.1111/anec.12553DOI Listing
April 2018
7 Reads

Severe brady-arrhythmias in systemic lupus erythematosus: prevalence, etiology and associated factors.

Lupus 2018 Aug 17;27(9):1415-1423. Epub 2018 Apr 17.

1 Centre for Prognosis Studies in Rheumatic Diseases, Toronto Lupus Clinic, University Health Network, Toronto, Canada.

Background Severe brady-arrhythmias, requiring a permanent pacemaker (PPM), have been sparsely reported in systemic lupus erythematosus (SLE). The aim of this study was to describe the characteristics of such arrhythmias in a defined lupus cohort. Patients and methods The database of the Toronto Lupus Clinic ( n = 1366) was searched for patients who received a PPM. Read More

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http://dx.doi.org/10.1177/0961203318770526DOI Listing
August 2018
3 Reads

Clinical and electrocardiographic presentations of transient trifascicular block in three cats.

J Vet Cardiol 2018 Jun 20;20(3):204-212. Epub 2018 Mar 20.

Cornell University College of Veterinary Medicine, 930 Campus Road, 14853, Ithaca, NY, USA. Electronic address:

This report describes transient trifascicular block in three cats presented with lethargy and inappetence, and elevated cardiac troponin I concentrations. The electrocardiogram (ECG) of cat 1 showed a sinus rhythm with pronounced first-degree atrioventricular (AV) block, right bundle branch block, and left anterior fascicular block. The ECG of cat 2 showed truncular left bundle branch block alternating with left anterior fascicular block coupled with prolonged PR intervals, second-degree heart block, and paroxysmal third-degree AV block. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17602734173020
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http://dx.doi.org/10.1016/j.jvc.2018.02.002DOI Listing
June 2018
6 Reads

Maternal steroid therapy for fetuses with second-degree immune-mediated congenital atrioventricular block: a systematic review and meta-analysis.

Acta Obstet Gynecol Scand 2018 Jul 18;97(7):787-794. Epub 2018 Apr 18.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, PA, USA.

Introduction: The aim of this study was to explore the effect of maternal fluorinated steroid therapy on fetuses affected by second-degree immune-mediated congenital atrioventricular block.

Material And Methods: Studies reporting the outcome of fetuses with second-degree immune-mediated congenital atrioventricular block diagnosed on prenatal ultrasound and treated with fluorinated steroids compared with those not treated were included. The primary outcome was the overall progression of congenital atrioventricular block to either continuous or intermittent third-degree congenital atrioventricular block at birth. Read More

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http://dx.doi.org/10.1111/aogs.13338DOI Listing
July 2018
16 Reads
1.990 Impact Factor

Treatment of intrahepatic cholestasis of pregnancy with ursodeoxycholic acid associated with improvement of fetal first-degree atrioventricular block.

Ultrasound Obstet Gynecol 2018 Dec;52(6):801-802

Fetal Medicine Unit, Department of Obstetrics and Gynecology, Hospital Clínico Universidad de Chile, Santiago de Chile, Chile.

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http://dx.doi.org/10.1002/uog.19032DOI Listing
December 2018
6 Reads
3.850 Impact Factor

Marked First-Degree Atrioventricular Block and Pseudo-Pacemaker Syndrome in a Pediatric Patient.

Pediatr Cardiol 2018 Mar 12;39(3):637-639. Epub 2018 Feb 12.

Division of Pediatric Cardiology, Children's Hospital of Pittsburgh of UPMC, One Children's Hospital Drive, 4401 Penn Avenue, Pittsburgh, PA, 15224, USA.

We describe a 17-year-old female who presented with 3 weeks of abdominal pain, exercise intolerance, and an episode of altered mental status found to have marked first-degree atrioventricular block. Exercise stress test and cardiac catheterization demonstrated pseudo-pacemaker syndrome, and a permanent pacemaker was placed. Following placement, she has resolution of symptoms and markedly improved exercise tolerance. Read More

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http://dx.doi.org/10.1007/s00246-018-1829-4DOI Listing
March 2018
4 Reads

Pregabalin-induced first degree atrioventricular block in a young patient treated for pain from extrapulmonary tuberculosis.

Monaldi Arch Chest Dis 2017 Sep 28;87(3):838. Epub 2017 Sep 28.

Federico II University School of Medicine.

Pregabalin, widely used in the treatment of several pain disorders, is usually well tolerated. Uncommonly, the drug may induce cardiac side effects, rarely prolongation of the PR interval. The latter has never been described in patients with healthy heart or normal renal function. Read More

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http://monaldi-archives.org/index.php/macd/article/view/838
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http://dx.doi.org/10.4081/monaldi.2017.838DOI Listing
September 2017
16 Reads

A case of cardiac sarcoidosis mimicking cardiac amyloidosis on cardiovascular magnetic resonance.

ESC Heart Fail 2018 04 5;5(2):306-310. Epub 2018 Feb 5.

Department of Cardiology and Nuclear Medicine, National Center for Global Health and Medicine, Tokyo, Japan.

A 52-year-old male visited our hospital with abnormal electrocardiogram and exertional fatigue. The electrocardiogram showed first-degree atrioventricular block, complete right bundle branch block, and inverted T waves in Leads II, III, aVF, V3, and V4. Echocardiography showed biventricular wall thickening involving granular sparkling of the interventricular septum. Read More

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http://doi.wiley.com/10.1002/ehf2.12263
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http://dx.doi.org/10.1002/ehf2.12263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880662PMC
April 2018
10 Reads

Development and Validation of a New Scoring System to Predict Survival in Patients With Myotonic Dystrophy Type 1.

JAMA Neurol 2018 May;75(5):573-581

Cardiology Department, Cochin Hospital, Filière Neuromusculaire, Paris-Descartes University, Sorbonne Paris Cité University, Assistance Publique-Hôpitaux de Paris, Paris, France.

Importance: Life expectancy is greatly shortened in patients presenting with myotonic dystrophy type 1 (DM1), the most common neuromuscular disease. A reliable prediction of survival in patients with DM1 is critically important to plan personalized health supervision.

Objective: To develop and validate a prognostic score to predict 10-year survival in patients with DM1. Read More

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http://dx.doi.org/10.1001/jamaneurol.2017.4778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885178PMC
May 2018
42 Reads

ECG Predictors of Cardiac Arrhythmias in Older Adults With Syncope.

Ann Emerg Med 2018 04 21;71(4):452-461.e3. Epub 2017 Dec 21.

Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Heath & Science University, Portland, OR.

Study Objective: Cardiac arrhythmia is a life-threatening condition in older adults who present to the emergency department (ED) with syncope. Previous work suggests the initial ED ECG can predict arrhythmia risk; however, specific ECG predictors have been variably specified. Our objective is to identify specific ECG abnormalities predictive of 30-day serious cardiac arrhythmias in older adults presenting to the ED with syncope. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01960644173190
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http://dx.doi.org/10.1016/j.annemergmed.2017.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866177PMC
April 2018
17 Reads

Electrocardiographic patterns and long-term training-induced time changes in 2484 elite football players.

Arch Cardiovasc Dis 2018 May 21;111(5):380-388. Epub 2017 Dec 21.

Service de cardiologie, institut Lorrain du cœur et des vaisseaux Louis-Mathieu, centre hospitalier universitaire de Nancy, 4, rue du Morvan, 54500 Vandœuvre-lès-Nancy, France.

Background: High-level physical training induces cardiac structural and functional changes, including 12-lead electrocardiogram modifications.

Objectives: The purpose of this cross-sectional longitudinal study was to establish a quantitative electrocardiographic profile in highly trained football players. Initial and serial annual electrocardiogram monitoring over subsequent years allowed us to investigate the long-term effects of exercise on cardiac conduction and electrophysiological remodelling. Read More

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http://dx.doi.org/10.1016/j.acvd.2017.10.005DOI Listing
May 2018
19 Reads

Severe cardiac toxicity following alcohol intake in a patient using therapeutic dose of propafenone.

Turk Kardiyol Dern Ars 2017 Dec;45(8):752-754

Department of Cardiology, Kartal Koşuyolu Yüksek İhtisas Training and Research Hospital, İstanbul, Turkey.

An unconscious, 25-year-old, male patient was brought to the emergency department. The patient's electrocardiography demonstrated a wide QRS interval and first-degree atrioventricular block. He was being treated with propafenone twice daily (450 mg) for paroxysmal atrial fibrillation. Read More

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http://dx.doi.org/10.5543/tkda.2017.84553DOI Listing
December 2017
8 Reads

Symptomatic first-degree atrioventricular block in a young woman after taking a fat burner supplement.

Int J Health Sci (Qassim) 2017 Nov-Dec;11(5):79-80

Department of Cardiology, Homerton University Hospital Homerton Row, London E9 6SR, UK.

A 22-year-old woman collapsed at home and was brought to the accident and emergency department. History revealed that she was fit and taken T5 capsule the night before the collapse. There was no history of similar collapses or seizure. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678045PMC
November 2017
9 Reads

Early Disseminated Lyme Disease Masquerading as Mononucleosis: A Case Report.

J Emerg Med 2017 Dec 6;53(6):e133-e135. Epub 2017 Nov 6.

Cooper University Hospital, Camden, New Jersey.

Background: Disseminated Lyme disease can be difficult to diagnose, as it begins with nonspecific signs and symptoms, which, if not treated correctly, can lead to atrioventricular conduction blocks and meningitis. In addition, the diagnosis can be further complicated by potentially false-positive test results.

Case Report: We report a case of early-disseminated Lyme disease presenting with Borrelia meningitis and concomitant Lyme carditis, which was misdiagnosed as mononucleosis. Read More

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http://dx.doi.org/10.1016/j.jemermed.2017.09.005DOI Listing
December 2017
10 Reads

Exercise induced complete atrioventricular block: Utility of exercise stress test.

J Electrocardiol 2018 Jan - Feb;51(1):153-155. Epub 2017 Sep 10.

Division of Cardiology, New York Medical College at Westchester Medical Center, Valhalla, NY, USA.

Exercise induced complete atrioventricular block (EIAVB) is a relatively uncommon condition. This phenomenon is clinically important because it can mimic symptoms of other cardiovascular conditions and may be associated with exercise intolerance and subsequent syncope. A 76year old man with long-standing hypertension and diabetes mellitus presented with recurrent episodes of lightheadedness and syncope with physical activity. Read More

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http://dx.doi.org/10.1016/j.jelectrocard.2017.09.001DOI Listing
September 2017
7 Reads

Recurrent extensive anterior myocardial infarction with left and right bundle branch block.

Ann Noninvasive Electrocardiol 2018 Mar 15;23(2):e12506. Epub 2017 Oct 15.

The Cardiovascular Institute of the First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning Province, China.

The diagnosis of myocardial infarction with left bundle branch block is difficult. We report a case of 56-year-old man with old extensive anterior myocardial infarction and left bundle branch block (masked each other). The recurrent myocardial infarction indicated right bundle branch block and first-degree atrioventricular block, making a clear diagnosis of complicated and interesting ECG. Read More

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http://dx.doi.org/10.1111/anec.12506DOI Listing
March 2018
8 Reads

Marked Symptomatic Sinus Bradycardia With New Onset First-Degree Atrioventricular Block After Concomitant Methadone and Trazodone Use.

Am J Ther 2018 Sep/Oct;25(5):e575-e577

Department of Internal Medicine, Metropolitan Hospital Center, New York Medical College, New York, NY.

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http://Insights.ovid.com/crossref?an=00045391-900000000-9871
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http://dx.doi.org/10.1097/MJT.0000000000000657DOI Listing
September 2017
13 Reads

Impact of waterborne and trophic mercury exposures on cardiac function of two ecologically distinct Neotropical freshwater fish Brycon amazonicus and Hoplias malabaricus.

Comp Biochem Physiol C Toxicol Pharmacol 2017 Oct 20;201:26-34. Epub 2017 Sep 20.

Department of Physiological Sciences, Federal University of São Carlos (UFSCar), São Carlos 13565-905, São Paulo, Brazil.

Metal pollutants have been considered one of the main factors underlying the depletion of biodiversity in natural populations unbalancing aquatic environments. The aim of this study was to evaluate the effects of exposure to inorganic Hg on myocardial contractility and the electrocardiogram (ECG) of two ecologically distinct Neotropical fish species, namely: matrinxã (Brycon amazonicus) and trahira (Hoplias malabaricus). Matrinxãs were exposed to a sublethal concentration of 0. Read More

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http://dx.doi.org/10.1016/j.cbpc.2017.09.004DOI Listing
October 2017
11 Reads

Predictors of permanent pacemaker implantation after transfemoral aortic valve implantation with the Lotus valve.

Am Heart J 2017 Oct 19;192:57-63. Epub 2017 Jul 19.

Department of Internal Medicine II, University of Ulm, Ulm, Germany. Electronic address:

Background: Permanent pacemaker implantation (PPMI) after transcatheter aortic valve implantation is of high clinical relevance, but PPMI rates differ widely between valve types. Although the Lotus valve can be repositioned, reported rates for PPMI are high. The predictors of PPMI after Lotus valve implantation have not been defined yet. Read More

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http://dx.doi.org/10.1016/j.ahj.2017.07.011DOI Listing
October 2017
26 Reads

Very low pacemaker rate following ACURATE neo transcatheter heart valve implantation.

EuroIntervention 2017 Dec;13(11):1273-1280

Heart Center Lucerne, Luzerner Kantonsspital, Lucerne, Switzerland.

Aims: The aim of this study was to investigate whether minimising trauma to the aortic annulus and left ventricular outflow tract reduces the occurrence of new conduction disorders and the need for permanent pacemakers.

Methods And Results: A total of 175 patients (58% female, mean age 83±6 years) underwent transfemoral TAVI with the Boston Scientific ACURATE neo at three centres in Europe. Prosthesis size selection was based on perimeter-derived annular diameter. Read More

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http://dx.doi.org/10.4244/EIJ-D-17-00252DOI Listing
December 2017
34 Reads

Envenomation by Micrurus psyches in French Guiana.

Bull Soc Pathol Exot 2017 Oct 14;110(4):276-280. Epub 2017 Aug 14.

Département de biologie médicale, hôpital d'instruction des armées Bégin, 94300, Saint-Mandé, France.

We report here the first known envenomation by Micrurus psyches, the so-called Carib coral snake, which occurred on April 2016 in the surroundings of Saint-Laurent-du-Maroni, Western French Guiana. Besides local neurological symptoms, it featured unexpected electrocardiogram changes, which were emergence of a first-degree atrioventricular block and biphasic T waves, both transient. NewWorld elapid venoms were not known for being cardiotoxic so far. Read More

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http://dx.doi.org/10.1007/s13149-017-0567-9DOI Listing
October 2017
3 Reads

Bone marrow cell migration to the heart in a chimeric mouse model of acute chagasic disease.

Mem Inst Oswaldo Cruz 2017 Aug;112(8):551-560

Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil.

Background: Chagas disease is a public health problem caused by infection with the protozoan Trypanosoma cruzi. There is currently no effective therapy for Chagas disease. Although there is some evidence for the beneficial effect of bone marrow-derived cells in chagasic disease, the mechanisms underlying their effects in the heart are unknown. Read More

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http://dx.doi.org/10.1590/0074-02760160526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530547PMC
August 2017
9 Reads

Conduction disturbance after isolated surgical aortic valve replacement in degenerative aortic stenosis.

J Thorac Cardiovasc Surg 2017 Nov 15;154(5):1556-1565.e1. Epub 2017 Jun 15.

Department of Cardiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Objective: Conduction disturbances are common in patients with aortic stenosis. We investigated the incidence, reversibility, and prognosis of conduction disorders requiring permanent pacemaker implantation in patients with degenerative aortic stenosis after isolated aortic valve replacement.

Methods: This was a retrospective study conducted at a tertiary care center. Read More

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http://dx.doi.org/10.1016/j.jtcvs.2017.05.101DOI Listing
November 2017
22 Reads

Vigabatrin Lacks Proarrhythmic Potential: Results from a Thorough QT/QTc Study in Healthy Volunteers.

Clin Ther 2017 Aug 28;39(8):1639-1648. Epub 2017 Jun 28.

Lundbeck LLC, Deerfield, Illinois.

Purpose: A thorough QT study was performed to assess the proarrhythmic potential of vigabatrin, an antiepileptic drug approved in the United States for the treatment of infantile spasms and refractory complex partial seizures.

Methods: In this Phase I, randomized, double-blind, placebo- and active-controlled (moxifloxacin), 4-sequence, crossover study conducted at a single center, healthy participants received 1 of 4 randomly assigned treatments: 3.0g vigabatrin solution (therapeutic dose) and 1 moxifloxacin placebo tablet; 6. Read More

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http://dx.doi.org/10.1016/j.clinthera.2017.06.006DOI Listing
August 2017
6 Reads