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Hum Vaccin Immunother 2018 Sep 20:1-7. Epub 2018 Sep 20.

p Faculty of Medicine, Department of Pediatrics , Eskisehir Osmangazi University , Eskisehir , Turkey.

Background: Febrile seizure is the most common childhood neurological disorder, is an important health problem with potential short- and long-term complications, also leading to economic burden and increased parental anxiety about fevers and seizures occurring in their children. There are no routine recommendation to detect etiological causes of FS for neurological perspective, further knowledge about the etiological causes of FS in children will support preventive measures and follow-up strategies. The aim of this study is to evaluate the percentage of respiratory viruses in children with FS. Read More

Pediatr Res 2017 01 27;81(1-2):202-209. Epub 2016 Sep 27.

Department of Physiology, School of Medical Sciences, University of Auckland, Auckland, New Zealand.

Acute postasphyxial encephalopathy around the time of birth remains a major cause of death and disability. The possibility that hypothermia may be able to prevent or lessen asphyxial brain injury is a "dream revisited". In this review, a historical perspective is provided from the first reported use of therapeutic hypothermia for brain injuries in antiquity, to the present day. Read More

Epilepsy Behav 2016 10 31;63:79-88. Epub 2016 Aug 31.

Department of Neurosurgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, USA; Brain Research Institute, University of California Los Angeles, Los Angeles, CA, USA.

Background: The management of drug-resistant epilepsy in children with Tuberous Sclerosis Complex (TSC) is challenging because of the multitude of treatment options, wide range of associated costs, and uncertainty of seizure outcomes. The most cost-effective approach for children whose epilepsy has failed to improve with first-line medical therapy is uncertain.

Methods: A review of MEDLINE from 1990 to 2015 was conducted. Read More

J Neurol Sci 2016 Apr 27;363:200-6. Epub 2016 Jan 27.

Institute of Neurology, Guangdong Medical University, Zhanjiang, Guangdong 524001, China. Electronic address:

Background: Recent studies indicate that increased expression of glyoxalase I (GLO1) could result in epileptic seizures; thus, this study further explored the association of GLO1 with epilepsy from the perspective of molecular genetics.

Material And Methods: GLO1 single nucleotide polymorphisms (SNPs; rs1130534, rs4746 and rs1049346) were investigated in cohort I (the initial samples: 249 cases and 289 controls). A replication study designed to confirm the positive findings in cohort I was performed in cohorts II (the additional samples: 130 cases and 191 controls) and I+II. Read More

Pediatr Surg Int 2016 Mar 28;32(3):277-83. Epub 2015 Dec 28.

DINOGMI, University of Genoa, Genoa, Italy.

Background: Fundoplication is considered a mainstay in the treatment of gastro-esophageal reflux. However, the literature reports significant recurrences and limited data on long-term outcome.

Aims: To evaluate our long-term outcomes of antireflux surgery in children and to assess the results of redo surgery. Read More

Epilepsy Behav 2014 Dec 15;41:114-8. Epub 2014 Oct 15.

Division of Neurology, Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Wayne State University School of Medicine, 3901 Beaubien Blvd., Detroit, MI 48201, USA. Electronic address:

Objective: The objective of this study was to evaluate the understanding of adolescent patients regarding epilepsy.

Methods: The SAFETY (Safety, Awareness, and Familiarity regarding Epilepsy in Teenage Years) questionnaire (content validity index: 0.96, Flesch readability score: 66. Read More

Curr Opin Neurol 2013 Apr;26(2):163-7

Child and Adolescent Department, Pediatric Neurology, University Hospitals, Geneva, Switzerland.

Purpose Of Review: This review presents the new terms and concepts proposed by the International League Against Epilepsy (ILAE) Classification Commission in 2010 to describe seizures and epilepsies. This is the first major revision in 21 years and reflects the rapid evolution in our understanding of the epilepsies.

Recent Findings: The article places these changes in an historical perspective, summarizes elements of the lively debate that followed publication, presents refinements addressing those concerns and discusses issues that remain to be addressed. Read More

Seizure 2012 Dec 29;21(10):764-9. Epub 2012 Aug 29.

College of Pharmacy, Al-Rashed University, Baghdad, Iraq.

Purpose: Aims of this study were to estimate the first-year medical care costs of newly diagnosed children with structural-metabolic epilepsy and to determine the cost-driving factors in the selected population.

Method: This was a prevalence-based retrospective chart review that included patients who attended a pediatric neurology clinic in a tertiary referral center in Malaysia. The total first-year medical care costs were estimated from the provider (i. Read More

World Neurosurg 2013 Sep-Oct;80(3-4):396-8. Epub 2012 Apr 3.

Division of Pediatric Neurosurgery, Rainbow Babies and Children's Hospital, The Neurological Institute, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

The history of surgical treatment for hemispheric epilepsy is rich with colorful twists and turns. The authors trace the evolution of the surgical treatment of hemispheric epilepsy from radical anatomic resections to current less invasive disconnection procedures. Anatomic hemispherectomy (AH) was first described by Dandy in 1928 as a treatment for gliomas. Read More

Int Rev Neurobiol 2008 ;83:91-111

Department of Neurology and Pediatrics, Division of Pediatric Neurology, Pediatric Comprehensive Epilepsy Program, Children's Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.

Adolescence is a time of many changes. It is a time of growing independence, physical and emotional change, accompanied by social insecurity. Girls tend to enter puberty ahead of their male peers, growing and changing physically. Read More

Epileptic Disord 2003 Jun;5(2):77-91

Case Western Reserve University, Ohio, USA.

While epilepsy can present at any age, this condition often occurs because of adverse events early in life. Pathogenetic mechanisms also cause deleterious consequences to the brain during prenatal life. For the epileptologist to fully appreciate developmental epileptogenesis, one must apply an ontogenetic approach (i. Read More