536 results match your criteria Fine-Needle Aspiration of Neck Masses

Ectopic Papillary Thyroid Carcinoma Presenting as Right Lateral Neck Mass: A Case Report.

J ASEAN Fed Endocr Soc 2022 20;37(1):103-106. Epub 2022 Apr 20.

Department of Pathology, College of Medicine, University of the Philippines Manila, Metro Manila, Philippines.

A lateral neck mass can be the initial presentation of a papillary thyroid carcinoma. A 24-year-old female presented with a 2.0 x 2. Read More

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Adult Cervical Thymic Cysts: A Narrative Review.

Ear Nose Throat J 2022 Jun 28:1455613221111490. Epub 2022 Jun 28.

Otorhinolaryngology Head and Neck Surgery and Communicatons Sciences Department, 37852King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

Objective: Thymic cysts are rare benign neck masses, accounting for less than 1% of all cervical masses. This study aims to discern different presentations, investigations, and treatment options of thymic cysts in adults by reviewing prior published studies from January 2010 to October 2021 to bridge the knowledge gap since the last review by Michalopoulos in 2011. Moreover, we present a case of a 28-year-old male with a left cervical thymic cyst. Read More

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Practice Models from my 16 years Performing Ultrasound-Guided Fine-Needle Aspiration of Superficial Masses at an Outpatient Clinic- Part II.

Semin Diagn Pathol 2022 Jun 15. Epub 2022 Jun 15.

Interventional Cytopathology, Precision Pathology, 7750 College Town Drive. Suite 102, Sacramento, CA 95826. Electronic address:

The second part focuses on my practice of USGFNA of lymph nodes, salivary glands, lesions of the head and neck, and breast masses. My experience with the handling and triage of various sorts of specimens, core needle biopsies, and cytology report timelines, with real-life anecdotes, is provided at the end. Read More

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Effects of COVID-19 pandemic on cytology: specimen adequacy in fine-needle aspiration of palpable head and neck masses.

J Am Soc Cytopathol 2022 Jul-Aug;11(4):234-240. Epub 2022 Apr 19.

Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.

Introduction: At our institution, palpation-guided fine-needle aspiration (FNA) is performed by the cytopathology service on an outpatient basis at the request of otolaryngologist surgeons. The aim of this study is to assess the effect of COVID lockdown measures on our FNA service with specific focus on adequacy rates.

Materials And Methods: All palpation-guided FNA performed in 2019 to 2020 were identified in our pathology database. Read More

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Core Needle Biopsy Can Early and Precisely Identify Large Thyroid Masses.

Front Oncol 2022 5;12:854755. Epub 2022 Apr 5.

Department of Surgical, Medical, Molecular Pathology and Critical Area, Unit of Endocrine Surgery, University Hospital of Pisa, Pisa, Italy.

Background: Large thyroid masses, particularly if rapidly growing, are often characterized by compression and infiltration of the vital structures of the neck. Therefore, an early and precise diagnosis, not only of malignancy but also of histotype, is mandatory to set up the right therapy. The aim of this study was to evaluate the diagnostic performance of fine needle aspiration cytology (FNAC) and core needle biopsy (CNB) in this setting. Read More

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[Diagnostic challenges in Kimura's disease].

Pol Merkur Lekarski 2022 Apr;50(296):128-130

Medical University of Lodz, Poland: Department of Nephrology, Hypertension and Kidney Transplantation.

Ultra-rare diseases occur with a frequency of 2 in 100 000 people or less. Kimura's disease (KD) affects less than 1 in 1 000 000 people. It is a benign, chronic inflammatory soft tissue disorder, accompanied by eosinophilia, raised immunoglobulin E (IgE) titer and the presence of painless subcutaneous masses, usually in the head and neck region. Read More

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[Indications for fine-needle aspiration and core needle biopsy for diagnosis of salivary gland tumors].

HNO 2022 Apr 4. Epub 2022 Apr 4.

Klinik für Hals-Nasen-Ohrenheilkunde, Universitätsklinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland.

Background: Salivary gland malignancies are rare neoplasms of the head and neck area. Preoperative clinical and imaging assessment of salivary gland masses is challenging. However, preoperative identification of malignancy is crucial for further treatment and for the course of the disease. Read More

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Cervical Thymic Cyst with parathyroid tissue - a diagnostic conundrum.

Autops Case Rep 2022 21;12:e2021361. Epub 2022 Feb 21.

All India Institute of Medical Sciences, Department of Pathology and Lab Medicine, Jodhpur, Rajasthan, India.

Cervical thymic cysts are relatively rare benign cystic lesions that tend to be diagnosed clinically as branchial cysts, which usually present as painless, enlarging neck masses. They can occur anywhere along the normal path of descent of thymic primordia from the angle of the mandible to the sternal notch, with mediastinal extension observed in approximately 50% of cases. They are usually seen in the first decade of life on the left side with a male predominance. Read More

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February 2022

Granular cell tumor of thyroid: a case series with molecular characterization highlighting unique pitfalls.

Endocrine 2022 05 17;76(2):395-406. Epub 2022 Feb 17.

University of Pittsburgh Medical Center, Pittsburgh, PA, USA.

Primary granular cell tumors (GCTs) of the thyroid are exceptionally rare. We report the clinicopathologic and molecular features of three cases and review the literature. Two patients (20-year-old, Case 1, and 26-year-old, Case 2, black American females) presented with painless masses with a preoperative fine-needle aspiration biopsy (FNAB) diagnosis of "Hürthle cell neoplasm," while one additional patient, 51-year-old white American female (Case 3), presented as an incidental finding within a background of chronic lymphocytic thyroiditis. Read More

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Single fiber reflectance spectroscopy for pancreatic cancer detection during endoscopic ultrasound guided fine needle biopsy: a prospective cohort study.

Int J Med Sci 2022 1;19(2):205-212. Epub 2022 Jan 1.

Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.

This study aimed to determine the ability of single fiber reflectance (SFR) spectroscopy incorporated in endoscopic ultrasound fine needle biopsy (EUS-FNB) procedures in the pancreas to distinguish benign and malignant pancreatic tissue in patient with pancreatic masses suspected for malignancy. This study was designed as a prospective observational single center study and included consecutive adult patients, who were scheduled for EUS-FNB of a solid pancreatic mass suspected for pancreatic ductal adenocarcinoma (PDAC). In total, seven optical parameters, derived from the absorption acquired spectra, were analyzed: blood volume fraction (BVF), microvascular saturation, average vessel diameter, bilirubin concentration (BIL), Mie amplitude, Mie slope and Rayleigh amplitude. Read More

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Huge Submandibular Gland Mucocele With Diagnostic Difficulties.

J Craniofac Surg 2022 Feb 4. Epub 2022 Feb 4.

Department of Oral and Maxillofacial Surgery/Orthodontics, Yokohama City University Hospital, Yokohama, Kanagawa, Japan.

Abstract: Submandibular gland mucoceles, which are very rare cystic lesions, make differentiation from other cystic neck masses such as plunging ranula and cystic lymphatic malformation difficult. The authors report a rare huge submandibular gland mucocele with diagnostic difficulties. A 39-year-old woman with painless swelling in the left submandibular region underwent OK-432 injection therapy with a diagnosis of plunging ranula at another hospital. Read More

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February 2022

A Rare Complication of Fine-Needle Aspiration of Neck Structures.

Case Rep Otolaryngol 2021 15;2021:8944119. Epub 2021 Dec 15.

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA.

Fine-needle aspiration (FNA) is a generally accepted tool for safe diagnostic evaluation in the workup of lesions and masses. Aside from the commonly discussed risks of infection and minor bleeding related to skin puncture, other more serious complications have been reported sparingly. We present two cases of pneumothorax from FNA of neck structures, which have been theorized but not previously reported to our knowledge. Read More

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December 2021

Squamous cell carcinoma of the uterine cervix metastasising to the thyroid gland: a case report.

Surg Case Rep 2021 Dec 15;7(1):255. Epub 2021 Dec 15.

Department of Surgery, District General Hospital Chilaw, Putlam, Chilaw, Sri Lanka.

Background: Carcinoma of the uterine cervix (cervical cancer) metastasising to the thyroid gland is a rare phenomenon and only a few cases have been reported. We discuss a patient with cervical cancer presenting with thyroid and cervical lymph node metastasis, exploring the diagnostic difficulty, evaluation and treatment options.

Case Presentation: A previously well 56-year-old female presented with multiple neck lumps for 4 months duration. Read More

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December 2021

Fine-needle aspiration cytology of an intrathyroidal nodule diagnosed as squamous cell carcinoma: A case report.

World J Clin Cases 2021 Nov;9(32):9982-9989

Department of Pathology, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.

Background: Both squamous cell carcinoma (SCC) and papillary thyroid carcinoma (PTC) are common malignant tumors in the neck. However, seldom has SCC of the thyroid been diagnosed. Further, cytological features of SCC and PTC have rarely been reported. Read More

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November 2021

Clinical diagnostic utility of ultrasound-guided fine needle aspiration biopsy in parotid masses.

Ear Nose Throat J 2021 Nov 24:1455613211058922. Epub 2021 Nov 24.

Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, 3158University of Alberta, Edmonton, AB, Canada.

Background: Fine needle aspiration (FNA) is a common diagnostic tool used in the initial evaluation of parotid masses. In the literature, variable diagnostic accuracy of FNA is reported. Therefore, when considering clinical management of these patients, the utility of FNA is unclear. Read More

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November 2021

Non-neoplastic Lesions among Lateral Neck Mass Specimens in a Tertiary Care Center: A Descriptive Cross-sectional Study.

JNMA J Nepal Med Assoc 2021 Jul 30;59(239):663-666. Epub 2021 Jul 30.

Department of Community Medicine, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.

Introduction: Lateral neck masses present clinically as neoplastic or non-neoplastic lesions of lymph nodes, salivary glands, and thyroid. Non-neoplastic lesions, if evaluated timely, may not transform into malignancy thus reducing clinical burden. A cytomorphological study using fine needle aspiration is a reliable method for the diagnosis of such masses. Read More

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Clinician's commentary: Atypia in salivary gland fine needle aspiration.

Diagn Cytopathol 2022 Apr 25;50(4):162-163. Epub 2021 Aug 25.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Due to the heterogenicity and morphological overlap among the broad spectrum of benign and malignant salivary gland lesions, cytopathology result interpretations can be challenging and variable even among the most experienced head and neck pathologist. There was no standardization of cytopathology result reporting until the recently proposed "Milan system for reporting salivary gland cytopathology" (MSRSGC). MSRSGC may offer more clarity and help minimize ambiguity, but surgeons, as part of multidisciplinary teams, do not only rely on the tiered stratification and risk of malignancy assessment. Read More

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Evaluation and Management of a Neck Mass.

Med Clin North Am 2021 Sep 12;105(5):827-837. Epub 2021 Jul 12.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA; Leonard Davis Institute of Health Economics, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

Neck masses are common physical examination findings seen in the outpatient setting but identifying an underlying cause can be challenging. A careful medical history should be obtained, and a thorough physical examination should be performed, which will guide the need for follow-up examination with imaging, biopsies, and specialist referrals. The goal of this article is to provide a working framework to evaluate and manage some of the most common causes of adult neck masses. Read More

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September 2021

Review of Head and Neck Masses in the Indian Population Based on Prevalence and Etiology With an Emphasis on Primary Diagnostic Modalities.

Nilam Bhasker

Cureus 2021 Jul 7;13(7):e16249. Epub 2021 Jul 7.

Pathology, Employees' State Insurance Corporation Hospital, Lucknow, IND.

Head and neck masses are classified as sebaceous cysts (epidermoid cysts), cervical lymphadenopathy, benign lipomas, lymph nodes, thyroid swellings, or tuberculosis lymphadenitis that may be painful or painless, adherent or fluctuant. In spite of this, they have distinct prognoses and pathological features. The anatomical location of the swelling and other demographic manifestations of the patient provide valuable information about the cause and type of swelling. Read More

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Submandibular lymph node metastasis of occult thyroid carcinoma first suspected to be a salivary gland tumor: a case report.

J Med Case Rep 2021 Jul 23;15(1):402. Epub 2021 Jul 23.

Department of Oral and Maxillofacial Surgery, Tokyo Women's Medical University, Medical Center East, 2-1-10, Nishiogu, Arakawa-ku, Tokyo, 116-8567, Japan.

Background: When diagnosing and treating neck masses, various diseases need to be considered, including benign or malignant tumors, lymph node-related diseases, and cysts. Thus, there may be cases in which making a definitive diagnosis is difficult on the basis of blood testing and imaging alone.

Case Presentation: The patient was an 80-year-old Japanese female who presented with swelling in the right submandibular area. Read More

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Thyroglobulin Measurement in Needle Aspiration for Detection of Recurrences and Neck Metastases in Patients with Differentiated Thyroid Carcinoma: Significance of Anti-Tg Antibodies.

Acta Clin Croat 2020 Jun;59(Suppl 1):9-17

1Department of Oncology and Nuclear medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; 2School of Medicine, University of Zagreb, Zagreb, Croatia; 3Faculty of Medicine, University of Osijek, Osijek, Croatia; 4Department for Nuclear Medicine and Radiation Protection, Osijek University Hospital Center, Croatia.

The worldwide incidence of differentiated thyroid cancer (DTC) has increased in recent decades, likely due to frequent use of cervical ultrasonography (US) and US-guided fine needle aspiration biopsy (FNA)., US is performed during follow-up after thyroidectomy, and US-guided FNA with cytology is used if suspicious cervical lymph nodes (LN) or thyroid bed masses are detected. Knowing that serum anti-Tg antibodies (sTgAb) affect the use of serum Tg (sTg) as a tumor marker, the aim of our study was to assess the usefulness of Tg determination in needle aspirates (FNA-Tg) in presence of sTgAb. Read More

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Accuracy, predictability and prognostic implications of fine-needle aspiration biopsy for parotid gland tumours: A retrospective case series.

Clin Otolaryngol 2021 09 31;46(5):1065-1072. Epub 2021 May 31.

Department of Otolaryngology - Head and Neck Surgery, Rabin Medical Center, Petah Tikva, Israel.

Objective: To evaluate the precision and utility of fine-needle aspiration (FNA) in differentiating between benign and malignant parotid tumours, and the implications of FNA results on management and outcomes.

Design: Retrospective case series.

Setting: Tertiary medical centre. Read More

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September 2021

Case Report: A New Entity: Multiple Differentiated Variant of Papillary Thyroid Carcinoma With Advanced Clinical Behavior.

Front Endocrinol (Lausanne) 2021 7;12:654638. Epub 2021 Apr 7.

Thyroid and Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, China.

There are many histological morphological types of papillary thyroid carcinoma (PTC), but the most frequently seen types are conventional. A single PTC commonly has a conventional and/or a variant morphological pattern. PTC with multiple (more than two) well-differentiated morphological patterns are extremely rare. Read More

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December 2021

Correlation Between Fine Needle Aspiration Cytology (FNAC) and Permanent Histopathology Results in Salivary Gland Masses.

Cureus 2021 Mar 18;13(3):e13976. Epub 2021 Mar 18.

College of Medicine, Department of Otolaryngology - Head & Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Jeddah, SAU.

Objective Fine-needle aspiration cytology (FNAC) has been widely accepted as a diagnostic safe method for preoperative assessment of salivary gland lesions. This diagnostic tool is inexpensive, easy to perform, relatively painless and it provides useful information to differentiate between benign and malignant salivary gland tumors that helps in the management and surgical planning. This study was undertaken to compare FNAC results with permanent histopathological findings of salivary gland tumors in order to assess its diagnostic accuracy. Read More

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Diagnosis and management of ectopic cervical thymus in children: Systematic review of the literature.

J Pediatr Surg 2021 Nov 11;56(11):2062-2068. Epub 2021 Mar 11.

Department of Paediatric Surgery, Monash Children's Hospital, Clayton, Melbourne, Australia; Department of Paediatrics, Monash University, Clayton, Melbourne, Australia; Department of Surgery, Monash University, Clayton, Melbourne, Australia. Electronic address:

Background/purpose: Ectopic cervical thymus (ECT) is a rare cause of neck swelling in children. Our aim was to evaluate the diagnostic and management challenges of this condition.

Methods: Systematic review of the literature (1997-2020) using PRISMA guidelines. Read More

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November 2021

Is there a Role for Frozen Section Evaluation of Parotid Masses After Preoperative Cytology or Biopsy Diagnosis?

Head Neck Pathol 2021 Sep 22;15(3):859-865. Epub 2021 Feb 22.

Department of Laboratory Medicine & Pathology, Mayo Clinic Arizona, 13400 E Shea Boulevard, Scottsdale, AZ, 85259, USA.

Fine-needle aspiration (FNA) biopsy reliably diagnoses parotid gland lesions preoperatively, whereas intraoperative frozen section (FS) has the additional benefit of assessing surgical margins and refining diagnoses; however, the role of FS in the setting of prior FNA diagnosis is not well established. Our aim was to determine whether FS should still be performed after a prior FNA/ CNB diagnosis. Parotid gland resections from January 2009 to January 2020 were identified; however, only patients who had both FNA and FS constituted our study population. Read More

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September 2021

Multiple simple cystic metastases in the lateral neck at presentation with papillary thyroid microcarcinoma: A case report.

Medicine (Baltimore) 2021 Jan;100(4):e23866

Department of Thyroid and Breast Surgery, Lishui Hospital of Zhejiang University, Lishui Municipal Central Hospital, Lishui.

Introduction: Metastasis of a papillary thyroid microcarcinoma (PTMC) in the lateral neck is characterized primarily by solid lymphadenopathy, although some cases may rarely present with a cervical cystic mass. We report a case of lateral cervical lymph node metastases of PTMC that appeared as a cystic lymphangioma of the lateral neck.

Patient Concerns: A 55-year-old man with a painless egg-sized mass in the right side of the neck that had been present for 1 month underwent physical examination, ultrasonography, computed tomography (CT), fine needle aspiration biopsy (FNAB), and intraoperative fast-frozen pathological examination, which indicated that the cystic masses in the neck were benign. Read More

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January 2021

Utility of ultrasound-guided fine needle aspiration cytology in assessing malignancy in head and neck pathology.

Cytopathology 2021 07 26;32(4):407-415. Epub 2021 Jan 26.

Otolaryngology Division, Azienda Ospedaliera Universitaria, Sassari, Italy.

Objective: Fine needle aspiration cytology (FNAC) is a well-established diagnostic procedure for head and neck masses not clearly originating from mucosal or cutaneous surfaces. We analysed head and neck masses evaluated over a 2-year period, to assess the reliability of FNAC for the evaluation of malignancy.

Methods: We enrolled all patients undergoing FNAC, from April 2013 to July 2015, in a single service of a large Italian university hospital. Read More

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The effect of Oxygen application with nCPAP for the prevention of desaturation during EBUS-TBNA.

Int J Clin Pract 2021 May 11;75(5):e14045. Epub 2021 Feb 11.

Department of Anesthesiology, Dokuz Eylul University, Izmir, Turkey.

Purpose: EBUS-TBNA is a frequently used diagnostic method for mediastinal/hilar lymphadenopathies and masses. This procedure is performed with intravenous sedation (IVS). During IVS, patients often develop hypoxemia and nasal oxygen delivery is insufficient in some patients. Read More

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Percutaneous Ultrasound-Guided Fine-Needle Aspiration Cytology and Core-Needle Biopsy for Laryngeal and Hypopharyngeal Masses.

Korean J Radiol 2021 04 30;22(4):596-603. Epub 2020 Nov 30.

Department of Radiation Oncology, School of Medicine, Kyungpook National University, Daegu, Korea.

Objective: To evaluate the feasibility and diagnostic performance of ultrasound (US)-guided fine-needle aspiration cytology and core-needle biopsy (US-FNAC/CNB) for the diagnosis of laryngo-hypopharyngeal masses.

Materials And Methods: This was a single-center prospective case series. From January 2018 to June 2019, we initially enrolled 40 patients with highly suspicious laryngo-hypopharyngeal masses on laryngoscopic examinations. Read More

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