516 results match your criteria Fine-Needle Aspiration of Neck Masses


Submandibular lymph node metastasis of occult thyroid carcinoma first suspected to be a salivary gland tumor: a case report.

J Med Case Rep 2021 Jul 23;15(1):402. Epub 2021 Jul 23.

Department of Oral and Maxillofacial Surgery, Tokyo Women's Medical University, Medical Center East, 2-1-10, Nishiogu, Arakawa-ku, Tokyo, 116-8567, Japan.

Background: When diagnosing and treating neck masses, various diseases need to be considered, including benign or malignant tumors, lymph node-related diseases, and cysts. Thus, there may be cases in which making a definitive diagnosis is difficult on the basis of blood testing and imaging alone.

Case Presentation: The patient was an 80-year-old Japanese female who presented with swelling in the right submandibular area. Read More

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Thyroglobulin Measurement in Needle Aspiration for Detection of Recurrences and Neck Metastases in Patients with Differentiated Thyroid Carcinoma: Significance of Anti-Tg Antibodies.

Acta Clin Croat 2020 Jun;59(Suppl 1):9-17

1Department of Oncology and Nuclear medicine, Sestre milosrdnice University Hospital Center, Zagreb, Croatia; 2School of Medicine, University of Zagreb, Zagreb, Croatia; 3Faculty of Medicine, University of Osijek, Osijek, Croatia; 4Department for Nuclear Medicine and Radiation Protection, Osijek University Hospital Center, Croatia.

The worldwide incidence of differentiated thyroid cancer (DTC) has increased in recent decades, likely due to frequent use of cervical ultrasonography (US) and US-guided fine needle aspiration biopsy (FNA)., US is performed during follow-up after thyroidectomy, and US-guided FNA with cytology is used if suspicious cervical lymph nodes (LN) or thyroid bed masses are detected. Knowing that serum anti-Tg antibodies (sTgAb) affect the use of serum Tg (sTg) as a tumor marker, the aim of our study was to assess the usefulness of Tg determination in needle aspirates (FNA-Tg) in presence of sTgAb. Read More

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Accuracy, predictability and prognostic implications of fine-needle aspiration biopsy for parotid gland tumours: A retrospective case series.

Clin Otolaryngol 2021 May 4. Epub 2021 May 4.

Department of Otolaryngology - Head and Neck Surgery, Rabin Medical Center, Petah Tikva, Israel.

Objective: To evaluate the precision and utility of fine-needle aspiration (FNA) in differentiating between benign and malignant parotid tumours, and the implications of FNA results on management and outcomes.

Design: Retrospective case series.

Setting: Tertiary medical centre. Read More

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Case Report: A New Entity: Multiple Differentiated Variant of Papillary Thyroid Carcinoma With Advanced Clinical Behavior.

Front Endocrinol (Lausanne) 2021 7;12:654638. Epub 2021 Apr 7.

Thyroid and Parathyroid Surgery Center, West China Hospital, Sichuan University, Chengdu, China.

There are many histological morphological types of papillary thyroid carcinoma (PTC), but the most frequently seen types are conventional. A single PTC commonly has a conventional and/or a variant morphological pattern. PTC with multiple (more than two) well-differentiated morphological patterns are extremely rare. Read More

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Correlation Between Fine Needle Aspiration Cytology (FNAC) and Permanent Histopathology Results in Salivary Gland Masses.

Cureus 2021 Mar 18;13(3):e13976. Epub 2021 Mar 18.

College of Medicine, Department of Otolaryngology - Head & Neck Surgery, King Saud bin Abdulaziz University for Health Sciences, King Abdullah International Medical Research Center, Ministry of National Guard Health Affairs, Jeddah, SAU.

Objective Fine-needle aspiration cytology (FNAC) has been widely accepted as a diagnostic safe method for preoperative assessment of salivary gland lesions. This diagnostic tool is inexpensive, easy to perform, relatively painless and it provides useful information to differentiate between benign and malignant salivary gland tumors that helps in the management and surgical planning. This study was undertaken to compare FNAC results with permanent histopathological findings of salivary gland tumors in order to assess its diagnostic accuracy. Read More

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Diagnosis and management of ectopic cervical thymus in children: Systematic review of the literature.

J Pediatr Surg 2021 Mar 11. Epub 2021 Mar 11.

Department of Paediatric Surgery, Monash Children's Hospital, Clayton, Melbourne, Australia; Department of Paediatrics, Monash University, Clayton, Melbourne, Australia; Department of Surgery, Monash University, Clayton, Melbourne, Australia. Electronic address:

Background/purpose: Ectopic cervical thymus (ECT) is a rare cause of neck swelling in children. Our aim was to evaluate the diagnostic and management challenges of this condition.

Methods: Systematic review of the literature (1997-2020) using PRISMA guidelines. Read More

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Is there a Role for Frozen Section Evaluation of Parotid Masses After Preoperative Cytology or Biopsy Diagnosis?

Head Neck Pathol 2021 Feb 22. Epub 2021 Feb 22.

Department of Laboratory Medicine & Pathology, Mayo Clinic Arizona, 13400 E Shea Boulevard, Scottsdale, AZ, 85259, USA.

Fine-needle aspiration (FNA) biopsy reliably diagnoses parotid gland lesions preoperatively, whereas intraoperative frozen section (FS) has the additional benefit of assessing surgical margins and refining diagnoses; however, the role of FS in the setting of prior FNA diagnosis is not well established. Our aim was to determine whether FS should still be performed after a prior FNA/ CNB diagnosis. Parotid gland resections from January 2009 to January 2020 were identified; however, only patients who had both FNA and FS constituted our study population. Read More

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February 2021

Multiple simple cystic metastases in the lateral neck at presentation with papillary thyroid microcarcinoma: A case report.

Medicine (Baltimore) 2021 Jan;100(4):e23866

Department of Thyroid and Breast Surgery, Lishui Hospital of Zhejiang University, Lishui Municipal Central Hospital, Lishui.

Introduction: Metastasis of a papillary thyroid microcarcinoma (PTMC) in the lateral neck is characterized primarily by solid lymphadenopathy, although some cases may rarely present with a cervical cystic mass. We report a case of lateral cervical lymph node metastases of PTMC that appeared as a cystic lymphangioma of the lateral neck.

Patient Concerns: A 55-year-old man with a painless egg-sized mass in the right side of the neck that had been present for 1 month underwent physical examination, ultrasonography, computed tomography (CT), fine needle aspiration biopsy (FNAB), and intraoperative fast-frozen pathological examination, which indicated that the cystic masses in the neck were benign. Read More

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January 2021

Utility of ultrasound-guided fine needle aspiration cytology in assessing malignancy in head and neck pathology.

Cytopathology 2021 Jul 26;32(4):407-415. Epub 2021 Jan 26.

Otolaryngology Division, Azienda Ospedaliera Universitaria, Sassari, Italy.

Objective: Fine needle aspiration cytology (FNAC) is a well-established diagnostic procedure for head and neck masses not clearly originating from mucosal or cutaneous surfaces. We analysed head and neck masses evaluated over a 2-year period, to assess the reliability of FNAC for the evaluation of malignancy.

Methods: We enrolled all patients undergoing FNAC, from April 2013 to July 2015, in a single service of a large Italian university hospital. Read More

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The effect of Oxygen application with nCPAP for the prevention of desaturation during EBUS-TBNA.

Int J Clin Pract 2021 May 11;75(5):e14045. Epub 2021 Feb 11.

Department of Anesthesiology, Dokuz Eylul University, Izmir, Turkey.

Purpose: EBUS-TBNA is a frequently used diagnostic method for mediastinal/hilar lymphadenopathies and masses. This procedure is performed with intravenous sedation (IVS). During IVS, patients often develop hypoxemia and nasal oxygen delivery is insufficient in some patients. Read More

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Percutaneous Ultrasound-Guided Fine-Needle Aspiration Cytology and Core-Needle Biopsy for Laryngeal and Hypopharyngeal Masses.

Korean J Radiol 2021 04 30;22(4):596-603. Epub 2020 Nov 30.

Department of Radiation Oncology, School of Medicine, Kyungpook National University, Daegu, Korea.

Objective: To evaluate the feasibility and diagnostic performance of ultrasound (US)-guided fine-needle aspiration cytology and core-needle biopsy (US-FNAC/CNB) for the diagnosis of laryngo-hypopharyngeal masses.

Materials And Methods: This was a single-center prospective case series. From January 2018 to June 2019, we initially enrolled 40 patients with highly suspicious laryngo-hypopharyngeal masses on laryngoscopic examinations. Read More

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Imaging of Head and Neck Cancer With CT, MRI, and US.

Semin Nucl Med 2021 Jan 6;51(1):3-12. Epub 2020 Aug 6.

Department of Radiology & Biomedical Imaging, University of California, San Francisco, San Francisco, CA.

Imaging of head and neck (HN) cancer is a challenge for many radiologists and largely due to the challenging anatomy in a small volume of the body. Additionally, multiple pathologies and the absence of an agreed-upon standard imaging protocol for staging and surveillance add complexity in choosing the most appropriate imaging study. Computed tomography (CT) is often the first-line imaging tool used as it is readily available, relatively cheaper than magnetic resonance (MR) and is rapidly acquired. Read More

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January 2021

Rosai-Dorfman disease of the pancreas: Cytologic analysis of three cases presenting as pancreatic masses.

Diagn Cytopathol 2021 Apr 15;49(4):E181-E186. Epub 2020 Oct 15.

Department of Pathology and Laboratory Medicine, Emory University, Atlanta, Georgia, USA.

Rosai-Dorfman Disease (RDD), or sinus histiocytosis with massive lymphadenopathy, is a rare entity characterized by proliferating S100-positive histiocytes. It is most commonly found in lymph nodes with extranodal involvement usually occurring in the head and neck. Pancreatic involvement is extremely rare. Read More

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Neck Procedures: Thyroid and Parathyroid.

Radiol Clin North Am 2020 Nov 17;58(6):1085-1098. Epub 2020 Sep 17.

Department of Radiology, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ 85054, USA.

Fine-needle aspiration (FNA) and core biopsy of masses in the neck predominantly include samples from thyroid nodules, parathyroids and lymph nodes. The diagnostic rate of a thyroid nodule FNA improves up to 6 passes and then does not significantly change. Thyroid FNA can be performed on patients who are anticoagulated. Read More

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November 2020

Surgeon-performed ultrasound in a head and neck surgical oncology clinic: saving time and improving patient care.

Eur Arch Otorhinolaryngol 2021 Jul 7;278(7):2455-2460. Epub 2020 Sep 7.

Head and Neck Surgical Oncology, Peter MacCallum Cancer Centre, 305 Grattan Street, Melbourne, VIC, 3000, Australia.

Introduction: Surgeon-performed ultrasound (SUS) for head and neck masses is increasingly being performed by head and neck surgeons. This is the first study assessing its impact in a head and neck surgical oncology clinic, examining the effect on various parameters.

Methods: Retrospective analysis was conducted on a database, analysing and comparing all new patients reviewed 6 months prior to (pre-SUS group) and 6 months following (post-SUS group) the introduction of SUS to the outpatient head and neck surgical oncology clinic. Read More

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Fine-needle aspiration cytology of head and neck masses: Is ultrasound guidance routinely warranted?

S Afr Med J 2020 Jul 29;110(8):713-714. Epub 2020 Jul 29.

Registrar, Division of Otorhinolaryngology, Faculty of Health Sciences, University of Cape Town, South Africa.

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Adenoid cystic carcinoma cytology: Salivary gland and nonsalivary gland.

Diagn Cytopathol 2020 Dec 18;48(12):1282-1289. Epub 2020 Aug 18.

Division of Cytopathology, Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland, USA.

Objectives: Adenoid cystic carcinoma (ACCA) is an uncommon primary malignancy of salivary glands and rarely nonsalivary tissue. This study aims to evaluate the diagnostic accuracy of ACCA on fine needle aspiration (FNA) material and the associated challenges.

Methods: A search on electronic pathology database from 2006 to 2016 at The Johns Hopkins Hospital found 83 cytology specimens diagnosed as ACCA, 49 with histology follow-up. Read More

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December 2020

Reply to letter to the editor "The role of fine-needle aspiration biopsy (FNAB) in the diagnostic management of parotid gland masses with emphasis on potential pitfalls".

Eur Arch Otorhinolaryngol 2020 10 7;277(10):2941. Epub 2020 Aug 7.

Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, University Hospital Motol, Charles University, V Uvalu 84, 150 06, Prague, Czech Republic.

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October 2020

Comparison of core needle biopsy and fine-needle aspiration in diagnosis of ma lignant salivary gland neoplasm: Systematic review and meta-analysis.

Head Neck 2020 10 16;42(10):3041-3050. Epub 2020 Jul 16.

Department of Radiology, Seoul National University Bundang Hospital, Seongnam, South Korea.

Background: In this meta-analysis, we compared the risk of obtaining nondiagnostic results and the diagnostic accuracy for detection of salivary gland malignancy between core needle biopsy (CNB) and fine-needle aspiration (FNA).

Methods: All published English-language studies comparing CNB and FNA diagnostic accuracy for salivary gland masses through December 2019 were searched. Pooled risk ratios (RRs) of nondiagnostic results, sensitivities, and specificities of CNB and FNA for salivary gland malignancy diagnosis were determined. Read More

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October 2020

Multiple Endocrine Neoplasia Type 2B Associated Mixed Medullary and Follicular Thyroid Carcinoma in A Chinese Patient with RET M918T Germline Mutation.

Endocr Metab Immune Disord Drug Targets 2021 ;21(3):554-560

Department of Head and Neck Surgery, Institute of Cancer and Basic Medicine (ICBM), Chinese Academy of Sciences, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, No.1 East Banshan Road, Hangzhou 310022, Zhejiang Province, China.

Background: Mixed medullary and follicular thyroid carcinoma (MMFC) displays heterogeneous morphological components and immunophenotypical features intermingled within the same lesion, which is rare and most described in the sporadic form. We report herein a Chinese patient with multiple endocrine neoplasia type 2B (MEN2B) harboring germline RET M918T and associated MMFC.

Methods: A case of a 39-year-old male patient with MEN2B presented palpable neck masses in both thyroid lobes (maximum sizes: left, 3. Read More

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January 2021

Diagnostic value of preoperative fine needle aspiration cytology in parotid gland tumors.

Diagn Cytopathol 2020 Nov 20;48(11):1075-1080. Epub 2020 Jun 20.

Department of Pathology, University of Health Sciences, Elazig Health Practices And Research Center, Elazig, Turkey.

Background: Salivary gland masses constitute a broad spectrum of lesions ranging from non-neoplastic to benign and malignant lesions. Parotid is the largest salivary gland and constitutes 75% to 80% of all salivary gland areas. 80% of parotid lesions are benign and 20% are malignant. Read More

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November 2020

Invasion of the thoracic duct by postlaryngectomy stomal recurrence: a case report.

J Med Case Rep 2020 Jun 13;14(1):68. Epub 2020 Jun 13.

Department of Otolaryngology-Head and Neck Surgery, The Second Xiangya Hospital, Central South University, 139 Renmin Road, Changsha, 410011, Hunan, PR China.

Background: Postlaryngectomy stomal recurrence can infiltrate the adjacent tissues of tracheal stoma. However, to the best of our knowledge, there is no report about postlaryngectomy stomal recurrence invading the thoracic duct with intra-mass accumulation of chylous fluid.

Case Presentation: Our patient was a 52-year-old Han man who presented with a cystic-solid mass on the left side of the tracheal stoma after total laryngectomy. Read More

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An approach to neck masses in adults.

Aust J Gen Pract 2020 05;49(5):267-271

MBBS, Surgical Registrar, Monash Health, Vic.

Background: Neck masses in adults are a common presentation for head and neck cancer. Head and neck cancer accounts for 3.4% of all malignancies in Australia, and the incidence of oropharyngeal squamous cell carcinoma is rising. Read More

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Introduction of surgeon-performed ultrasound to a head and neck clinic: indications, diagnostic adequacy and a new clinic model?

ANZ J Surg 2020 05 30;90(5):861-866. Epub 2020 Apr 30.

Head and Neck Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.

Background: Surgeon-performed ultrasound (SUS) changes management and surgical decision-making. It allows for immediate ultrasound-guided fine-needle aspiration (US-FNA) for the work-up of neck masses, lymph node metastases and thyroid nodules. We examined the introduction of SUS to an Australian Head and Neck cancer unit, identifying situations where it was used, and evaluated the diagnostic adequacy and accuracy of US-FNA. Read More

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Unusual metastasis of papillary thyroid cancer to the pancreas, liver, and diaphragm: a case report with review of literature.

BMC Surg 2020 Apr 22;20(1):82. Epub 2020 Apr 22.

Department of Pancreatic Surgery, West China Hospital, Sichuan University, GuoXue Lane No 37, Chengdu, 610041, China.

Background: Papillary thyroid cancer (PTC) is the most common form of well-differentiated endocrine malignancy. Distant metastases of PTC are rare and usually occur in the bones, lungs, and thoracic lymph nodes despite the common locoregional metastases to the lymph nodes of the neck. The metastasis of PTC to the pancreas is extremely rare. Read More

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A rapidly enlarging painful neck mass in a 59-year-old woman.

Clin Case Rep 2020 Mar 24;8(3):570-571. Epub 2020 Jan 24.

Division of Endocrinology Department of Medicine Walter Reed National Military Medical Center Bethesda MD USA.

Primary care physicians and endocrinologists should be aware that neck masses with concerning features like, in this case, a delay in evaluation and treatment may dramatically shorten a patient's life. Read More

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Fine-needle aspiration washout in the diagnosis of cystic parathyroid adenoma.

BMJ Case Rep 2020 Mar 10;13(3). Epub 2020 Mar 10.

Department of Endocrine Surgery, Scientific Center of Surgery named after M.A.Topchubashov, Baku, Azerbaijan.

Cystic parathyroid adenomas are one of the rare causes of neck masses. Due to its rarity, it causes misdiagnosis and wrong treatments and has undesirable consequences. The measurement of parathyroid hormone in fine-needle aspiration washout fluid is a minimally invasive, safe method for the diagnosis of parathyroid cysts and seems to be more useful than Tc-99m sestamibi (MIBI) parathyroid single photon emission computed tomography (SPECT)/CT. Read More

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The role of fine-needle aspiration biopsy (FNAB) in the diagnostic management of parotid gland masses with emphasis on potential pitfalls.

Eur Arch Otorhinolaryngol 2020 Jun 27;277(6):1763-1769. Epub 2020 Feb 27.

Department of Otorhinolaryngology and Head and Neck Surgery, First Faculty of Medicine, University Hospital Motol, Charles University, V Uvalu 84, 150 06, Prague, Czech Republic.

Purpose: The treatment strategy of parotid gland tumours depends mainly on the histopathological type of the lesion. Fine-needle aspiration biopsy (FNAB) is recommended in preoperative diagnostics. The aim of the study was to evaluate the FNAB standing in the diagnostic algorithm of parotid gland lesions and to correlate FNAB results in relation to the definitive histopathological diagnosis. Read More

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Pre-sternal thyroid swellings: a case of rare aberrant site recurrence and review of literature.

Thyroid Res 2019 21;12:12. Epub 2019 Nov 21.

3Department of Transfusion Medicine, All India Institute of Medical Sciences, Rishikesh, India.

Background: Thyroid swellings enlarge caudally into the mediastinum behind the sternum. Pre-sternal swelling of thyroid origin is very rare. We present our case of pre-sternal thyroid swelling which was albeit a surprisingly rare site of papillary thyroid carcinoma recurrence and review of pre-sternal thyroid swellings reported till date. Read More

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November 2019

Educational Case: Developmental Neck Masses and Other Neck Tumors.

Acad Pathol 2019 Jan-Dec;6:2374289519888735. Epub 2019 Nov 22.

Department of Pathology, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, OH, USA.

.. Read More

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November 2019