6,081 results match your criteria Fibrous Dysplasia


Orthodontic treatment of patient with maxillofacial fibrous dysplasia: A case report.

J Clin Exp Dent 2019 Mar 1;11(3):e296-e302. Epub 2019 Mar 1.

College of Dental Medicine, Medical University of South Carolina, Charleston SC, USA.

Fibrous dysplasia is a benign skeletal disorder in which the normal bone and marrow are replaced by fibrous tissue and haphazardly distributed woven bone. The aim of this case report is to discuss the orthodontic treatment of a 13-year-old patient with fibrous dysplasia in the left maxilla. The patient had rotated maxillary second premolars, moderate crowding in both maxillary and mandibular arches with low maxillary frenal attachment. Read More

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http://dx.doi.org/10.4317/jced.55584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461730PMC

Limb lengthening and deformity correction in children with abnormal bone.

Injury 2019 Apr 8. Epub 2019 Apr 8.

Russian Ilizarov Scientific Centre for Restorative Traumatology and Orthopaedics, 6, M. Ulyanova Street, 640014, Kurgan, Russian Federation. Electronic address:

Flexible intramedullary nailing (FIN) provides multiple advantages in limb lengthening and progressive deformity correction in combination with external fixation. The article presents brief literature review and authors' experience in limb lengthening of abnormal bone (Ollier's disease, fibrous dysplasia, osteogenesis imperfecta). Titanium and, especially, hydroxyapatite-coated bent elastic nails in combination with external fixator are appropriate in limb lengthening of abnormal bone in children. Read More

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http://dx.doi.org/10.1016/j.injury.2019.03.045DOI Listing

Comparison of histochemical staining techniques for detecting mast cells in oral lesions.

Biotech Histochem 2019 Apr 15:1-10. Epub 2019 Apr 15.

a Department of Oral Pathology and Microbiology , Maratha Mandal's NGH Institute of Dental Sciences and Research Centre , Belgaum , India.

Mast cells are large cells with granular cytoplasm that participate in wound healing, angiogenesis and defense against pathogens. They also contribute to inflammation by initiating innate and acquired immunity. The granules of these cells exhibit characteristic staining properties. Read More

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http://dx.doi.org/10.1080/10520295.2019.1597986DOI Listing

Surgical Approach to Frontal Sinus Osteoma: A Systematic Review.

Am J Rhinol Allergy 2019 Apr 5:1945892419839895. Epub 2019 Apr 5.

1 Department of Otolaryngology-Head and Neck Surgery, University of Texas Medical Branch, Galveston, Texas.

Background: Osteoma of the paranasal sinuses are benign bony masses most commonly found in the frontal sinus. In the past, due to the anatomical complexity of the frontal sinus, these often required an open approach, but with the invention of angled tools and endoscopes, many rhinologists are now attempting endoscopic or combined resections. No large systematic reviews currently exist that describe the surgical management of frontal sinus osteoma. Read More

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http://dx.doi.org/10.1177/1945892419839895DOI Listing
April 2019
4 Reads

68Ga-PSMA Uptake in Fibrous Dysplasia.

Clin Nucl Med 2019 Mar 29. Epub 2019 Mar 29.

Unit of Nuclear Medicine, Aosta Regional Hospital, Aosta, Italy.

Prostate cancer is one of the most common malignancies. Imaging tools play an important role throughout the entire process of the disease. The scenario, however, is going to change. Read More

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http://Insights.ovid.com/crossref?an=00003072-900000000-9718
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http://dx.doi.org/10.1097/RLU.0000000000002546DOI Listing
March 2019
1 Read

Pathological Neck of Femur Fracture with Failed Osteosynthesis in Adolescent: A Report of Two Cases.

J Orthop Case Rep 2018 Nov-Dec;8(6):88-91

Department of Orthopaedics, Sri Sathya Sai Institute of Higher Medical Sciences, Prasanthigram, Puttaparthi, Andhra Pradesh, India.

Introduction: Non-union of the neck of femur fractures in adolescents is a complex problem, especially if there is an underlying pathology such as fibrous dysplasia or unicameral bone cyst. Treatment is challenging and needs careful selection of a combination of strategies.

Case Report: We present two such cases with a history of failed osteosynthesis with a sliding hip screw. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424325PMC

Multi-analytic study of a probable case of fibrous dysplasia (FD) from certosa monumental cemetery (Bologna, Italy).

Int J Paleopathol 2019 Mar 23;25:1-8. Epub 2019 Mar 23.

Department of Cultural Heritage, University of Bologna, via degli Ariani 1, 48121, Ravenna, Italy; Department of Human Evolution, Max Planck Institute for Evolutionary Anthropology, Deutscher Platz 6, 04103, Leipzig, Germany.

Objective: To evaluate, via a multidisciplinary approach, a distinctive paleopathological condition, believed to be fibrous dysplasia, found on a 19th/20th century skeleton from Certosa Monumental Cemetery, Bologna, Italy.

Materials: A skeletonized cranium and mandible recovered from an ossuary in 2014.

Methods: Pathological alterations were analysed by radiological examination, dental macrowear, histopathological and genetic analyses. Read More

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http://dx.doi.org/10.1016/j.ijpp.2019.03.003DOI Listing
March 2019
1 Read

[Differential diagnosis of cemento-osseous dysplasia of the maxilla. A case report].

Rev Esp Patol 2019 Apr - Jun;52(2):120-124

Servicio de Anatomía Patológica, Hospital Nuestra Señora del Rosario, Instituto Jiménez-Ayala, Madrid, España.

Cemento-osseous dysplasia is a benign lesion which affects the jaw bones. It is a frequent incidental finding but no aggressive therapy is necessary. However, it may be confused with more aggressive entities, such as ossifying and cementifying fibroma, which do require treatment. Read More

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http://dx.doi.org/10.1016/j.patol.2018.03.003DOI Listing
January 2018
1 Read

Gα signaling in skeletal development, homeostasis and diseases.

Curr Top Dev Biol 2019 28;133:281-307. Epub 2018 Dec 28.

Department of Developmental Biology, Harvard School of Dental Medicine, Boston, MA, United States. Electronic address:

Skeletal development is exquisitely controlled both spatially and temporally by cell signaling networks. Gα is the stimulatory α-subunit in a heterotrimeric G protein complex transducing the signaling of G-protein-coupled receptors (GPCRs), responsible for controlling both skeletal development and homeostasis. Gα, encoded by the GNAS gene in humans, plays critical roles in skeletal development and homeostasis by regulating commitment, differentiation and maturation of skeletal cells. Read More

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http://dx.doi.org/10.1016/bs.ctdb.2018.11.019DOI Listing
December 2018
1 Read

Polyostotic Fibrous Dysplasia Mimicking Osseous Metastases.

Cureus 2019 Jan 14;11(1):e3884. Epub 2019 Jan 14.

Internal Medicine, Florida Hospital, Orlando, USA.

Fibrous dysplasia (FD) is a benign bone disorder, in which normal bone structure is replaced by fibrous connective tissue. Polyostotic FD is also related to McCune-Albright syndrome with possible endocrine disorder and Cafe-au-lait macules. Although FD commonly presents as craniofacial bone abnormality, atypical presentation can be misleading and pose a difficulty in clinical diagnosis. Read More

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http://dx.doi.org/10.7759/cureus.3884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420325PMC
January 2019
1 Read

Feline Hypertrophic Cardiomyopathy: The Consequence of Cardiomyocyte-Initiated and Macrophage-Driven Remodeling Processes?

Vet Pathol 2019 Mar 21:300985819837717. Epub 2019 Mar 21.

1 The Veterinary Cardiac Pathophysiology Consortium, Institute of Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Zürich, Switzerland.

vHypertrophic cardiomyopathy (HCM) is the most commonly diagnosed cardiac disease in cats. The complex pathophysiology of HCM is still far from clear, but myocardial remodeling is a key process, and cardiomyocyte disarray, interstitial fibrosis, leukocyte infiltration, and vascular dysplasia are described histopathologic features. The present study systematically investigated the pathological processes in HCM, with the aim to shed more light on its pathogenesis. Read More

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http://dx.doi.org/10.1177/0300985819837717DOI Listing
March 2019
4 Reads

Benign Fibro-Osseous Lesions of the Head and Neck.

Head Neck Pathol 2019 Mar 18. Epub 2019 Mar 18.

Department of Radiology, Naval Medical Center San Diego, San Diego, CA, USA.

Benign fibro-osseous lesions (BFOLs) are a particularly challenging set of diagnoses for the pathologist. This diverse collection of diseases includes fibrous dysplasia, ossifying fibroma and cemento-osseous dysplasia. While all three conditions have similar microscopic presentations, their treatment and prognosis differ, demanding an accurate and definitive diagnosis. Read More

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http://dx.doi.org/10.1007/s12105-018-0992-5DOI Listing
March 2019
2 Reads

Shepherd's crook deformity: How to set it straight. A five-step surgical guide.

J Orthop Surg (Hong Kong) 2019 Jan-Apr;27(1):2309499019834362

Department of Orthopaedics and Traumatology, Ganga Hospital, Coimbatore, Tamil Nadu, India.

Purpose:: Fibrous dysplasia (FD) of the proximal femur can result in severe deformity and disability. The results of surgical management in such situations have been reported to be poor. We present a novel, five-step surgical treatment to correct proximal femoral deformity in FD. Read More

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http://dx.doi.org/10.1177/2309499019834362DOI Listing
March 2019
1 Read

A Method for Reconstruction of Anterior Commissure Glottal Webs With Endoscopic Fibro-Mucosal Flaps.

Ann Otol Rhinol Laryngol 2019 Mar;128(3_suppl):82S-93S

1 Department of Surgery, Harvard Medical School, Boston, MA, USA.

Background:: Anterior-commissure (AC) cicatrization and web formation is a difficult problem that can result from a variety of clinical scenarios. An advancement-rotation flap utilizing papillomatous epithelium and subepithelial fibrous tissue has been previously described. For patients in whom there was not excessive redundant papillomatosis covering the AC web, including other clinical scenarios, a microlaryngoscopic procedure was designed to lengthen the glottal/subglottal aperture using substantial local fibro-mucosal tissue. Read More

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http://dx.doi.org/10.1177/0003489418820031DOI Listing
March 2019
6 Reads

The orthopaedic management of long bone deformities in genetically and acquired generalized bone weakening conditions.

Authors:
T Wirth

J Child Orthop 2019 Feb;13(1):12-21

Department of Orthopaedics, Klinikum Stuttgart, Olgahospital, Stuttgart, Germany.

Purpose: Diseases such as osteogenesis imperfecta, fibrous dysplasia, hypophosphataemic rickets and others lead to soft and weak bones and long bone deformity in affected patients. As a consequence, these patients lose their walking capacity and functional abilities of the upper extremities as well.

Methods: In combination with bisphosphonate treatment and physical rehabilitation programmes surgical interventions are being applied to correct and stabilize the deformed and less mechanically resistant long bones. Read More

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http://dx.doi.org/10.1302/1863-2548.13.180184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376434PMC
February 2019
2 Reads

Radiological Findings of Craniofacial Fibrous Dysplasia.

Turk Neurosurg 2018 Nov 21. Epub 2018 Nov 21.

Tokat Gaziosmanpasa University Medicine School.

Aim: Fibrous dysplasia (FD) is relatively rare in craniofacial region compared to other regions of body. In the present study, radiological findings of FD detected in patients who had computed tomography (CT) and/or magnetic resonance imaging (MRI) were evaluated.

Material And Methods: This study included a total of 25 patients (17 female and 8 male) who were found to have FD based on CT examinations in March 2010-July 2018 period. Read More

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http://dx.doi.org/10.5137/1019-5149.JTN.24627-18.2DOI Listing
November 2018
6 Reads

"Banana patella", fibrous dysplasia of patella: A rare case report.

J Clin Orthop Trauma 2019 Mar-Apr;10(2):418-421. Epub 2018 May 18.

Gujarat Cancer Research Institute, Ahmedabad, India.

Introduction: Patella is a very uncommon site for primary bone tumours and fibrous dysplasia lesion in patella has never been reported. Fibrous dysplasia is a benign fibrosseous lesion of the bone where the fibrous connective tissue replaces the normal bone.

Case Report: We report a case of 23 years female with 7 years history of progressive swelling and anterior knee pain. Read More

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http://dx.doi.org/10.1016/j.jcot.2018.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382953PMC

Fibrous Dysplasia and Juvenile Psammomatoid Ossifying Fibroma: A Case of Mistaken Identity.

Cleft Palate Craniofac J 2019 Feb 27:1055665619833294. Epub 2019 Feb 27.

1 Division of Plastic and Reconstructive Surgery, Lurie Children's Hospital of Chicago, Northwestern Feinberg School of Medicine, Chicago, IL, USA.

Juvenile psammomatoid ossifying fibroma (JPOF) is a rare benign osseous tumor, usually presenting in the midface. There are many similarities in location, presentation, and radiographic appearance between fibrous dysplasia (FD) and JPOF. Awareness of this entity is important for craniofacial surgeons, as surgical timing and intraoperative management differ between these tumors. Read More

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http://dx.doi.org/10.1177/1055665619833294DOI Listing
February 2019
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Malignant transformation of craniofacial fibrous dysplasia: a systematic review of overall survival.

Neurosurg Rev 2019 Feb 27. Epub 2019 Feb 27.

Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Tiantan Xili No. 6, Beijing, 100050, China.

The incidence of malignant transformation of fibrous dysplasia (FD) is very rare. Thus, the available knowledge of its characteristics, management, and survival is scarce. Here, we present a systemic review of fibrous dysplasia that had undergone malignant transformation. Read More

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http://dx.doi.org/10.1007/s10143-019-01089-1DOI Listing
February 2019

Dental implants in a patient with left mandibular fibrous dysplasia: Two-year outcomes on the normal and affected sides.

J Stomatol Oral Maxillofac Surg 2019 Feb 11. Epub 2019 Feb 11.

Oral and Maxillofacial surgery department, Rouen university hospital, 1, rue de Germont, 76031 Rouen, France; Laboratory of anatomy, Rouen faculty of medicine, 22, boulevard Léon-Gambetta, 76031 Rouen, France; French national institute for health (Inserm), LIMICS UMR-1142, 76031 Rouen, France.

Dental rehabilitation raises specific challenges in patients with mandibular fibrous dysplasia. We report the 2-year post-operative outcomes on the normal and affected sides in a 64-year-old female with focal left mandibular fibrous dysplasia and bilateral posterior edentulism. On the left, bone shaving of the lesion to restore sufficient vertical height was followed by the insertion of two dental implants. Read More

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http://dx.doi.org/10.1016/j.jormas.2019.02.005DOI Listing
February 2019

Fibrous dysplasia with secondary aneurysmal bone cyst-a rare case report and literature review.

Oral Maxillofac Surg 2019 Mar 13;23(1):101-107. Epub 2019 Feb 13.

Department of Pathology, Center of Health Sciences, Federal University of Santa Catarina, University Campus, Trindade, Florianópolis, 88.040-370, Santa Catarina, Brazil.

Introduction: Fibrous dysplasia (FD) and aneurysmal bone cyst (ABC) are uncommon non-neoplastic intraosseous lesions, and the occurrence of concomitant FD and ABC is extremely rare.

Case Report: An 11-year-old boy presented with gradual progressive enlargement of his right zygomatic bone over 4 years prior to presentation. Computed tomography revealed a lesion with a central bony area showing a ground-glass appearance surrounded by a well-defined expansile lesion with internal septations. Read More

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http://dx.doi.org/10.1007/s10006-019-00741-wDOI Listing
March 2019
1 Read

Treatment of diaphyseal pathological fractures in children with monostotic fibrous dysplasia using cortical strut allografts and internal plating: A retrospective clinical study.

Medicine (Baltimore) 2019 Feb;98(5):e14318

Department of Orthopaedic Surgery, The Affiliated Southeast Hospital of Xiamen University, Zhangzhou.

Children with fibrous dysplasia (FD) chronically suffer from pain, pathological fractures, and limb deformities. The most effective methods for managing the associated pathological fractures remain controversial. The purpose of this study was to evaluate the clinical results of the treatment of diaphyseal pathological fractures in children with monostotic fibrous dysplasia (MFD) using cortical strut allografts and internal plating. Read More

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http://dx.doi.org/10.1097/MD.0000000000014318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380873PMC
February 2019
6 Reads

The need for bone biopsies in the diagnosis of new bone lesions in patients with a known primary malignancy: A comparative review of 117 biopsy cases.

J Bone Oncol 2019 Feb 18;14:100213. Epub 2018 Dec 18.

Department of Orthopedics, Zhongshan Hospital, Fudan University, 180# Fenglin Road, Xuhui district, Shanghai, China.

Objective: This study used a clinical dataset to investigate the proportion of the newly found bone lesions in malignant patients diagnosed by biopsy as being benign, malignant but unrelated to the primary malignancy, or bone metastases of the primary malignancy. The clinical factors that might affect the correlation between bone lesions and the primary malignancy were also analyzed. It is expected to obtain some information contributing to the clinical decision-making regarding the need for biopsy of these lesions from the research results. Read More

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http://dx.doi.org/10.1016/j.jbo.2018.100213DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329701PMC
February 2019
3 Reads

Management of Fibrous Dysplasia of Proximal Femur by Internal Fixation Without Grafting: A Retrospective Study of 19 Patients.

J Am Acad Orthop Surg Glob Res Rev 2018 Oct 2;2(10):e057. Epub 2018 Oct 2.

Orthopedic Surgery Department, Cairo University, Cairo, Egypt (Dr. Ebeid), the Orthopedic Surgery Department, Menoufia University, Menoufia, Egypt (Dr. Hasan and Mesregah), and the Orthopedic Surgery Department, Keck School of Medicine, University of Southern California, Los Angeles, California (Dr. Mesregah).

Introduction: This paper assesses whether treating patients with fibrous dysplasia of proximal femur by internal fixation with correction of the deformity, if present, without grafting is enough or not.

Methods: This study is a retrospective study using patient's medical records, including analysis of 19 patients with fibrous dysplasia of proximal femur treated by internal fixation only and followed up between 2000 and 2017 for at least 2 years. Epidemiologic data, clinical manifestations, radiologic and histologic investigations, surgery, functional outcomes, and complications in these patients were analyzed. Read More

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http://dx.doi.org/10.5435/JAAOSGlobal-D-18-00057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324889PMC
October 2018
2 Reads

Prevalence and Clinical Features of Mazabraud Syndrome: A Multicenter European Study.

J Bone Joint Surg Am 2019 Jan;101(2):160-168

Department of Orthopaedic Surgery (B.C.J.M., M.A.J.v.d.S., and S.P.D.D.), Endocrinology Division, Department of Medicine (N.M.A.-D. and N.A.T.H.), and Department of Pathology (J.V.M.G.B.), Leiden University Medical Center, Leiden, the Netherlands.

Background: Mazabraud syndrome is a rare disorder, characterized by the presence of fibrous dysplasia (FD) with associated intramuscular myxomas. Data are scarce on the prevalence, clinical features, and natural history of this disorder and outcomes. In this multicenter study, we evaluated a series of patients from 6 European centers. Read More

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http://dx.doi.org/10.2106/JBJS.18.00062DOI Listing
January 2019
6 Reads

A rare case report of craniofacial fibrous dysplasia.

J Oral Maxillofac Pathol 2018 Sep-Dec;22(3):406-409

Department of Oral Pathology, School of Dental Sciences, Sharda University, Greater Noida, Uttar Pradesh, India.

Fibrous dysplasia (FD) is a fibro-osseous lesion of the osseous structures of the body. The exact cause is unknown; however, recently, the cause has been reported to be postzygomatic somatic mutation in guanine nucleotide-binding protein, alpha stimulating 1 gene located at chromosome 20q13.2. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_211_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306600PMC
January 2019
11 Reads

Age-Related Changes and Effects of Bisphosphonates on Bone Turnover and Disease Progression in Fibrous Dysplasia of Bone.

J Bone Miner Res 2019 Jan 15. Epub 2019 Jan 15.

Skeletal Diseases and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

Fibrous dysplasia (FD) is a mosaic disease in which bone is replaced with fibro-osseous tissue. Lesions expand during childhood, reaching final burden by age 15 years. In vitro data suggest that disease activity decreases in adulthood; however, there is no clinical data to support this concept. Read More

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http://doi.wiley.com/10.1002/jbmr.3649
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http://dx.doi.org/10.1002/jbmr.3649DOI Listing
January 2019
6 Reads

Gnathodiaphyseal dysplasia with a novel R597I mutation of ANO5: Mandibular reconstruction strategies.

J Stomatol Oral Maxillofac Surg 2019 Jan 11. Epub 2019 Jan 11.

Assistance Publique - Hôpitaux de Paris, Service de chirurgie maxillofaciale et plastique, Hôpital Universitaire Necker - Enfants Malades, Université Paris Descartes, Sorbonne Paris Cité, 75015, Paris, France. Electronic address:

Gnathodiaphyseal Dysplasia (GDD) is a rare, often misdiagnosed, autosomal-dominant disorder due to point mutations in the ANO5 gene. GDD combines craniofacial fibro-osseous lesions, dental loss and progressive curvature and cortical thickening of long bones and vertebra, causing pathological fractures. Diagnosis is based on bone pathology and mutation screening. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24687855193000
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http://dx.doi.org/10.1016/j.jormas.2019.01.005DOI Listing
January 2019
11 Reads

Freeman-Burian syndrome.

Orphanet J Rare Dis 2019 01 10;14(1):14. Epub 2019 Jan 10.

FSRG deGruyter-McKusick Institute of Health Sciences, Buckhannon, USA.

Clinical Description: Freeman-Burian syndrome (FBS) is a rare congenital myopathic craniofacial syndrome. Considerable variability in severity is seen, but diagnosis requires the following: microstomia, whistling-face appearance (pursed lips), H or V-shaped chin defect, and prominent nasolabial folds. Some patients do not have limb malformations, but essentially all do, typically camptodactyly with ulnar deviation of the hand and talipes equinovarus. Read More

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https://ojrd.biomedcentral.com/articles/10.1186/s13023-018-0
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http://dx.doi.org/10.1186/s13023-018-0984-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327538PMC
January 2019
9 Reads
3.358 Impact Factor

Hepatic Lesions Associated With McCune Albright Syndrome.

J Pediatr Gastroenterol Nutr 2019 Apr;68(4):e54-e57

Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

McCune-Albright syndrome (MAS) results from a GNAS gene mutation. It is associated with café au lait macules, fibrous dysplasia, and several endocrinopathies to include gonadotropin-independent precocious puberty, growth hormone excess, Cushing syndrome, thyroid disease, and renal phosphate wasting. It is recognized to be a rare cause of neonatal cholestasis. Read More

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http://dx.doi.org/10.1097/MPG.0000000000002266DOI Listing
April 2019
5 Reads

Surgical Treatment of Cervical Spine Fibrous Dysplasia: Case Report and Literature Review.

Int J Spine Surg 2018 Dec 21;12(6):659-664. Epub 2018 Dec 21.

Spine Unit, University Hospital of Vall d'Hebron, Barcelona, Spain.

Background: Fibrous dysplasia (FD) is an uncommon benign intramedullary fibro-osseous lesion. Cervical spine compromise is rare with only cases reported. Currently, the natural history of cervical FD is poorly understood, and its treatment remains controversial. Read More

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http://dx.doi.org/10.14444/5082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314346PMC
December 2018
2 Reads

[Fibrous dysplasia in a 12-year-old boy with severe house dust mite allergy].

Ugeskr Laeger 2019 Jan;181(2)

In this case report, a two-year-old boy debuted with irritative and obstructive nasal symptoms and a positive house dust mite allergy test. Antihistamines and nasal steroids were prescribed, but he had persistent nasal symptoms. An initial ear-nose-throat examination was without pathology. Read More

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January 2019
3 Reads

Serum periostin levels and severity of fibrous dysplasia of bone.

Bone 2019 Apr 4;121:68-71. Epub 2019 Jan 4.

INSERM UMR 1033, Université de Lyon, Division of Rheumatology, Edouard Herriot University Hospital, 5 Place d'Arsonval, 69003 Lyon, France.

Fibrous dysplasia of bone (FD) is a rare congenital bone disease, characterized by a fibrous component in the bone marrow. Periostin has been extensively researched because of its implication in various fibrotic or inflammatory diseases. Periostin may be associated with the burden or the severity of FD. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S87563282193000
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http://dx.doi.org/10.1016/j.bone.2019.01.004DOI Listing
April 2019
12 Reads

Giant cell reparative granuloma of the scapula: report of a case and literature review.

Skeletal Radiol 2019 Jan 4. Epub 2019 Jan 4.

Department of Orthopedics and Orthopedic Oncology, University of Padova, Via Giustiniani 3, Padova, Italy.

Giant cell reparative granulomas (GCRGs) are non-neoplastic inflammatory lesions, usually observed in the maxilla, mandible or small bones of the hands and feet. These lesions present a wide range of morphology and the misinterpretation with other giant cell lesions can often occur. We report the case of a 47-year-old woman with GCRG in the left scapula, presenting some uncommon features: the location (scapula) and age at presentation, the lack of underlying bone disease such as Paget's disease or fibrous dysplasia, the large aggressive expansile aspect of the lesion. Read More

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http://dx.doi.org/10.1007/s00256-018-3132-0DOI Listing
January 2019
6 Reads

Florid cemento-osseous dysplasia: Report of 2 cases.

J Clin Exp Dent 2018 Nov 1;10(11):e1145-e1148. Epub 2018 Nov 1.

MD, DDS, MS, PhD, EBOS, OMFS. Chairman and Professor of Oral and Maxillofacial Surgery, School of Medicine and Health Sciences, University of Barcelona. Director of the Master's Degree Program in Oral Surgery and Implantology (EFHRE International University/FUCSO). Coordinator/Researcher of the IDIBELL Institute. Head of the Oral Surgery, Implantology and Maxillofacial Surgery Department of the Teknon Medical Center, Barcelona (Spain).

Introduction: Florid cemento-osseous dysplasia is a non-neoplastic fibro-osseous lesion which often has an asymptomatic slow growth. Unfortunately, these lesions are usually diagnosed through routine radiographic examination. The aim of this study was to describe the main clinical, radiological and histological characteristics of two case reports diagnosed with florid cemento-osseous dysplasia. Read More

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http://dx.doi.org/10.4317/jced.55288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311402PMC
November 2018

Midfacial degloving approach for management of the maxillary fibrous dysplasia: a case report.

Maxillofac Plast Reconstr Surg 2018 Dec 6;40(1):38. Epub 2018 Dec 6.

1Department of Oral and Maxillofacial Surgery, Dental Hospital, Kyung-hee University Hospital at Gang-dong, #892 Dongnam-ro, Gangdong-gu, Seoul, 05278 Republic of Korea.

Background: Fibrous dysplasia (FD) is a benign bone lesion characterized by the progressive replacement of normal bone with fibro-osseous connective tissue. The maxilla is the most commonly affected area of facial bone, resulting in facial asymmetry and functional disorders. Surgery is an effective management option and involves removing the diseased bone via an intraoral approach: conservative bone shaving or radical excision and reconstruction. Read More

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http://dx.doi.org/10.1186/s40902-018-0177-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6281586PMC
December 2018
1 Read

Mazabraud's Syndrome: A Case Report And Up-To-Date Literature Review.

Endocr Metab Immune Disord Drug Targets 2018 12 25. Epub 2018 Dec 25.

Endocrinology and Metabolism Unit, University-Hospital S. Maria della Misericordia of Udine, 33100 Udine. Italy.

Objective: Mazabraud's syndrome is a rare form of bone fibrous dysplasia associated with intramuscular myxomas. Fibrous dysplasia, is generally localized to pelvis and femur and it results in a fragile bone with deformities, pain, pathological fractures and functional impairment. Intramuscular myxomas, are rare benign mesenchymal neoplasms that exceptionally may evolve to malignant forms. Read More

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http://dx.doi.org/10.2174/1871530319666181226103700DOI Listing
December 2018
18 Reads

A Case of Fibrous Dysplasia with Bilateral Shepherd Crook Deformity Treated with Dynamic Hip Screw Fixation.

J Orthop Case Rep 2018 May-Jun;8(3):33-37

Department of Orthopaedics, Sri Ramachandra Medical University, Chennai, Tamil Nadu, India.

Introduction: Fibrous dysplasia is a rare benign disorder of the skeletal system characterized by fibro-osseous proliferation with intervening areas of normal or immature bone in the intramedullary region. It can either be a monostotic (involves one bone) or a polyostotic (involves more than one bone) presentation and usually occurs equally in males and females. Deformities such as scoliosis and shepherd's crook deformity are frequently encountered in the polyostotic form. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298711PMC
December 2018
5 Reads

Orthognathic surgery for patients with fibrous dysplasia involved with dentition.

Maxillofac Plast Reconstr Surg 2018 Dec 3;40(1):37. Epub 2018 Dec 3.

1Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, 2177 Dalgubeol-daero, Jung-gu, Daegu, 41940 Republic of Korea.

Background: Fibrous dysplasia (FD) is characterized by the replacement of normal bone by abnormal fibro-osseous connective tissue and typically treated with surgical contouring of the dysplastic bone. When dysplastic lesions involve occlusion, not only is surgical debulking needed, orthognathic surgery for correction of dentofacial deformity is mandatory. However, the long-term stability of osteotomized, dysplastic bone segments is a major concern because of insufficient screw-to-bone engagement during surgery and the risk of FD lesion re-growth. Read More

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http://dx.doi.org/10.1186/s40902-018-0176-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6275155PMC
December 2018
1 Read

Surgical Treatment of Fibroosseous Lesion in Young Patient with Reduced Mouth Opening.

Craniomaxillofac Trauma Reconstr 2018 Dec 16;11(4):314-319. Epub 2017 Nov 16.

Department of Oral and Maxillofacial Surgery and Maxillofacial Prosthodontics, Faculty of Dentistry, Federal University of Pelotas, Pelotas, Brazil.

Fibrous dysplasia is a benign fibroosseous disorder that can affect the maxillary bones, causing aesthetic deformity and functional impairment. This article reports the case of a 13-year-old male patient at the time of diagnosis. The patient showed increased facial volume with relevant asymmetry, having reported the onset of the condition 12 months before. Read More

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http://dx.doi.org/10.1055/s-0037-1608697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224290PMC
December 2018
1 Read

A Systematic Literature Review of Patients With Carotid Web and Acute Ischemic Stroke.

Stroke 2018 Dec;49(12):2872-2876

From the Department of Neurology, University of Minnesota Medical School, Minneapolis (A.J.Z., P.D., D.A., J.K., B.J., C.S.).

Background and Purpose- Carotid web (CW) is a rare form of focal fibromuscular dysplasia defined as an abnormal shelf-like projection of intimal fibrous tissue into the carotid bulb. It is theorized that CW leads to ischemic stroke secondary to blood flow stasis and subsequent embolization. The natural history and optimal management of CW are unclear. Read More

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http://dx.doi.org/10.1161/STROKEAHA.118.021907DOI Listing
December 2018
10 Reads

Atypical localization of intraosseous angioleiomyoma in the rib of a pediatric patient: a case report.

BMC Med Imaging 2018 12 19;18(1):54. Epub 2018 Dec 19.

Institute of Pathology, School of Medicine, University of Belgrade, Dr Subotica 1, 11000, Belgrade, Republic of Serbia.

Background: This is the first reported case of a primary intraosseous angioleiomyoma and the second case of a primary leiomyoma of the rib, irrespective of age. Angioleiomyomas mostly occur in patients of advanced age, in any part of the body, particularly the lower extremities and present as painful, slow-growing nodules in the dermis, subcutaneous fat or deep fascia. Other localizations, especially bone, are considered extremely rare, as well as their occurrence in paediatric patients. Read More

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http://dx.doi.org/10.1186/s12880-018-0297-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300016PMC
December 2018
6 Reads

Sensory disturbance along the inferior alveolar nerve as a first clinical sign of multiple florid cemento-osseous dysplasia of the mandible-A case report.

Int J Surg Case Rep 2018 22;53:452-457. Epub 2018 Nov 22.

Centre for Oral and Maxillofacial Surgery, University of Dental Medicine and Oral Health, Danube Private University, Steiner Landstraße 124, 3500, Krems-Stein, Austria. Electronic address:

Introduction: Florid cemento-osseous dysplasia (FCOD) is a rare, benign, slow growing, multifocal fibro-osseous tumour originating from the periodontal ligament. The lesion is characterised by regular bone-structure replacement with fibrous tissue and dysplastic bone. The initial characteristics of FCOD, depending on localisation, resemble those of periapical lesions of inflammatory origin, potentially leading to misdiagnosis. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.11.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277216PMC
November 2018
1 Read

[Tumor hip prosthesis in fibrous dysplasia of proximal femur. Case report].

Acta Ortop Mex 2018 Jul-Aug;32(4):225-228

Unidad Médica de Alta Especialidad del Hospital de Traumatología y Ortopedia de Puebla del Instituto Mexicano del Seguro Social. Puebla, México.

Background: fibrous dysplasia is characterized by the formation of fibrous tissue that generates immature malformed trabeculae. Their involvement may be monostotic or poliostotic.

Case Report: Thirty years old female with fibrous dysplasia of the left hip. Read More

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December 2018

First two cases of craniomaxillofacial fibrous dysplasia from Nepal - case series.

Clin Cosmet Investig Dent 2018 26;10:269-274. Epub 2018 Nov 26.

Department of Oral and Maxillofacial Surgery, Chitwan Medical College and Teaching Hospital, Bharatpur-10, Chitwan, Nepal.

Fibrous dysplasia is a benign fibro-osseous disease of the bone, which is most commonly associated with congenital mutations in cAMP regulating protein Gsα coded by gene. Often it is seen involving the craniofacial skeleton and can range from an asymptomatic monostotic form to polyostotic variant involving almost all the bones of the skull, thereby leading to functional and esthetic problems. This requires a continuous monitoring of the involved region throughout the life of the patient, even after the surgical interventions. Read More

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http://dx.doi.org/10.2147/CCIDE.S178599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263244PMC
November 2018
2 Reads

Scedosporium apiospermum invasive sinusitis presenting as extradural abscess.

Eur Ann Otorhinolaryngol Head Neck Dis 2019 Apr 4;136(2):119-121. Epub 2018 Dec 4.

Département d'otorhinolaryngologie/chirurgie cervico-faciale/chirurgie de la base du crâne, université Paris-Diderot, hôpital Lariboisière, AP-HP, Paris, France.

Introduction: Chronic invasive fungal rhinosinusitis (CIFR) is a rare entity generally observed in immunodepressed subjects. The pathogen most frequently identified is Aspergillus spp. Imaging generally reveals invasive pseudoneoplastic features. Read More

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http://dx.doi.org/10.1016/j.anorl.2018.11.009DOI Listing
April 2019
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Activation of RANK/RANKL/OPG Pathway Is Involved in the Pathophysiology of Fibrous Dysplasia and Associated With Disease Burden.

J Bone Miner Res 2019 Feb 29;34(2):290-294. Epub 2018 Nov 29.

Skeletal Disorders and Mineral Homeostasis Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA.

Fibrous dysplasia of bone (FD) is a mosaic disease caused by mutations in GNAS. Constitutive activation of the α-subunit of the G stimulatory protein (Gαs) leads to dysregulated proliferation of bone marrow stromal cells (BMSCs), generating expansile lesions of fibrotic tissue and abnormal bone. Local bone remodeling regulation by BMSCs is also altered, and FD tissue is characterized by abundant osteoclast-like cells that may be essential for lesion expansion. Read More

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http://doi.wiley.com/10.1002/jbmr.3602
Publisher Site
http://dx.doi.org/10.1002/jbmr.3602DOI Listing
February 2019
21 Reads