Oral Surg Oral Med Oral Pathol Oral Radiol 2015 Jan 28;119(1):92-100. Epub 2014 Sep 28.
Associate Professor, Division of Oral Pathology, Department of Pathology, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.
Objective: To investigate central lesions of the jaws dominated by foamy macrophages (foam cells), which are interpreted to be "central xanthomas of the jaws" and to differentiate this condition from reported cases of jaw nonossifying fibroma/fibrous cortical defect and benign fibrous histiocytoma of bone.
Study Design: The study is a literature review and a retrospective analysis of clinical, radiographic, microscopic, and immunohistochemical features of five new cases of this condition.
Results: The lesion has a predilection for the mandible in adults of variable ages, with the potential to become very large and destructive; however, it has a very low recurrence rate, if any, following surgical curettage. Read More