Am J Transl Res 2021 15;13(5):4812-4818. Epub 2021 May 15.
Department of Orthopedics, Zhujiang Hospital, Southern Medical University Guangzhou 510282, Guangdong Province, China.
Objective: To investigate of the Wnt pathway serum regulator expression levels and their relationship with bone metabolism (BM) in thoracolumbar osteoporotic vertebral compression fracture (OVCF) patients.
Methods: In this study, 40 healthy controls (group A), 33 osteoporotic patients (group B), and 47 thoracolumbar OVCF patients (group C) were recruited as the study cohort during the same period. The Wnt pathway serum regulator levels, bone density, BM-related inflammatory cytokines, bone formation markers, and bone resorption markers were compared among the three groups, and the correlation between the Wnt pathway serum regulators and BM was analyzed. Read More