Search Our Scientific Publications & Authors

Neurogastroenterol Motil 2020 May 31:e13882. Epub 2020 May 31.

Section of Pediatrics, Department of Translational Medical Science, University of Naples "Federico II", Naples, Italy.

Background: High-resolution anorectal manometry (HR-ARM) is expected to be better than conventional manometry. Our aim was to characterize HR-ARM pressures in children with functional constipation (FC), with or without fecal incontinence (FI).

Methods: Children with diagnosis of FC, with or without FI, according to Rome-IV criteria, were enrolled. Read More

Int J Colorectal Dis 2020 May 30. Epub 2020 May 30.

Department of Surgery, Anorectal Physiology Laboratory, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Purpose: This study aims to analyze the quality of life in patients with an ileal pouch-anal anastomosis (IPAA) and to investigate the association between height and type of the anastomosis, the number of stage procedures and age, and the fecal continence outcomes.

Methods: This is a cross-sectional retrospective study in patients who had undergone IPAA between 1992 and 2016 (N = 133). We sent questionnaires to 102 eligible patients (64% response rate). Read More

Int Urogynecol J 2020 May 30. Epub 2020 May 30.

Gothenburg Continence Research Centre, Institute of Clinical Sciences, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden.

Introduction And Hypothesis: A systematic survey on the association between childhood nocturnal enuresis (CNE) and adult pelvic floor disorders (PFDs) has not been presented previously. The aim was to describe the prevalence of PFDs and lower urinary tract symptoms in nulliparous women, with or without a history of CNE, at the age of ≥ 5 years.

Methods: This national survey of urinary (UI) and fecal incontinence (FI) and symptoms of pelvic organ prolapse (sPOP) was a random sample of 20,000 nulliparous women aged 25-64 years conducted in 2014. Read More

Chirurg 2020 May 30. Epub 2020 May 30.

Klinik und Poliklinik für Allgemein‑, Viszeral‑, Transplantations‑, Gefäß- und Kinderchirurgie, Universitätsklinikum Würzburg, Oberdürrbacher Straße 6, 97080, Würzburg, Deutschland.

Background: Traumatic anal sphincter muscle defects often occur after childbirth and surgery and can lead to fecal incontinence that requires further treatment.

Objective: The aim of this article is to illustrate the etiology of traumatic sphincter muscle defects, the treatment options of subsequent fecal incontinence and their evaluation on the basis of current studies.

Material And Methods: Selected studies are presented. Read More

Dig Dis Sci 2020 May 28. Epub 2020 May 28.

Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

Background: Fecal urgency is classically associated with diarrhea, but is also common in individuals with normal bowel habits or constipation. Its etiology, particularly in non-diarrhea individuals, is unclear.

Methods: We examined data from 368 individuals with and without diarrhea who underwent three-dimensional high-resolution anorectal manometry and balloon expulsion test. Read More

CMAJ Open 2020 Apr-Jun;8(2):E414-E419. Epub 2020 May 28.

Departments of Obstetrics and Gynecology (Ross, Fast, Slade) and Family Medicine (Miyagishima, Soos, Taylor, Drummond), University of Alberta; Women & Children's Health Research Institute (Ross), Edmonton, Alta.; Departments of Family Medicine (Garies, Jackson, Doraty, Drummond) and Community Health Sciences (Williamson), University of Calgary, Calgary, Alta.

Background: To date, there has been no validated method to identify cases of pelvic floor disorders in primary care electronic medical record (EMR) data. We aimed to develop and validate symptom-based case definitions for urinary incontinence, fecal incontinence and pelvic organ prolapse in women, for use in primary care epidemiologic or clinical research.

Methods: Our retrospective study used EMR data from the Southern Alberta Primary Care Research Network (SAPCReN) and the Canadian Primary Care Sentinel Surveillance Network (CPCSSN) in southern Alberta. Read More

World Neurosurg 2020 May 24. Epub 2020 May 24.

Department of Neurosurgery, The University of Tokyo Hospital, Tokyo, Japan.

Background: Ventriculoperitoneal (VP) shunt placement is a common and standard treatment for hydrocephalus, and these shunts function appropriately in the presence of a pressure gradient between the ventricular and abdominal cavities.

Case Description: We encountered two cases of shunt malfunction due to a rise in intra-abdominal pressure (IAP), mainly caused by constipation and excessive accumulation of enteric gas. Although aggressive bowel regimens were implemented, this management failed in both cases. Read More

Neonatal Netw 2020 May;39(3):147-157

Neonatal tumors occur infrequently; sacrococcygeal teratoma (SCT) is a rare and abnormal mass often diagnosed on antenatal ultrasound. An SCT may cause serious antenatal complications, requires surgery in the neonatal period, and can lead to various long-term sequelae including fecal incontinence or constipation, urinary incontinence, and lower extremity mobility impairment. Even rarer are SCTs that include intraspinal extension necessitating complex neurosurgical intervention to relieve possible spinal cord compression or tumor tissue resection. Read More

Tech Coloproctol 2020 May 22. Epub 2020 May 22.

Department of Digestive and Oncologic Surgery, Edouard Herriot University Hospital, 69003, Lyon, France.

Colorectal Dis 2020 May 22. Epub 2020 May 22.

Department of General Surgery, Midland Regional Hospital, Mullingar, Ireland.

The case of a 27-year-old primigravida woman with a fourth degree perineal tear following an instrumental vaginal delivery is described in Video S1. This case was performed in the operating theatre under spinal anaesthetic as a category two emergency. Anal sphincter tears carry a significant risk of faecal incontinence and rectovaginal fistula; careful closure of each layer is essential in preventing these complications and ensuring optimal quality of life. Read More

Rehabilitacion (Madr) 2019 Oct 1. Epub 2019 Oct 1.

Servicio de Rehabilitación y Medicina Física, Hospital Universitario Santa Cristina, Madrid, España.

Tarlov, or perineural cysts, are lesions of the nerve root usually located at the sacral level of the spine. Their cause is unclear. These cysts are generally identified as an incidental finding and are usually asymptomatic. Read More

Curr Geriatr Rep 2020 Jun 9;9(2):64-71. Epub 2020 Mar 9.

Department of Obstetrics and Gynecology Hospital of the University of Pennsylvania 3400 Spruce Street Philadelphia, PA 19104.

Purpose Of Review: The purpose of this article is to review the various forms of incontinence, highlight their impact on older women, and to explore current literature regarding the link between physical activity, physical function, and incontinence.

Recent Findings: Both urinary and fecal incontinence become more prevalent with age, and are associated with significant morbidity. In parallel, there is a well-established decline in physical function that occurs with age. Read More

PLoS One 2020 21;15(5):e0232739. Epub 2020 May 21.

Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway.

Objectives: Systemic sclerosis (SSc) is an auto-immune, multi organ disease marked by severe gastrointestinal (GI) involvement and gut dysbiosis. Here, we aimed to determine the safety and efficacy of fecal microbiota transplantation (FMT) using commercially-available anaerobic cultivated human intestinal microbiota (ACHIM) in SSc.

Methods: Ten patients with SSc were randomized to ACHIM (n = 5) or placebo (n = 5) in a double-blind, placebo-controlled 16-week pilot. Read More

World J Surg 2020 May 20. Epub 2020 May 20.

Department of Coloproctology, Seoul Yang Hospital, Seoul, Republic of Korea.

Background: Conventionally, the Thiersch operation has typically involved blind positioning of the sling, and sling tension is subjectively based on a rule-of-thumb estimate. The aim of this study was to describe standardized methods for performing the Thiersch operation.

Methods: Seventeen patients with fecal incontinence underwent the calibrated method of the Thiersch procedure. Read More

J Laparoendosc Adv Surg Tech A 2020 May 15. Epub 2020 May 15.

Department of Surgery, St. Mark's Hospital, London, United Kingdom.

The aim of this prospective, nonrandomized, observational study was to present our results in operative treatment of complex anal fistulas using video-assisted anal fistula treatment (VAAFT) procedure with a curative intent in 2 years follow-up period. Between March 2016 and March 2018, 73 patients underwent the VAAFT procedure. Postoperative follow-up was 2 years, up to March 2020. Read More

Minim Invasive Surg 2020 22;2020:3057528. Epub 2020 Jan 22.

Pediatric Surgery Department, Al-Azhar University Hospitals, Cairo, Egypt.

Purpose: To compare laparoscopic mesh rectopexy with laparoscopic suture rectopexy. . The prospective study was conducted at Pediatric Surgery Department, Al-Azhar University Hospitals, Cairo, Egypt between Feb 2010 and Jan 2015. Read More

Pediatr Surg Int 2020 May 13. Epub 2020 May 13.

Children's Health Ireland at Temple Street, Dublin, Ireland.

Aim: To compare the quality of life (QoL) in children with spina bifida with a control group of their peers using a validated questionnaire, the Neurogenic Bowel Dysfunction Score (NBDS).

Methods: The NBDS questionnaire was prospectively distributed to children attending a multi-disciplinary Spina Bifida clinic and healthy controls attending pediatric urology clinics. A score (out of 41) was assigned to each child based on their responses to the validated questionnaire. Read More

J Pediatr Gastroenterol Nutr 2020 May 12. Epub 2020 May 12.

Clinical Assistant Professor of Pediatrics, The Florida State University, Assistant Professor of Pediatrics, UCF College of Medicine, Center for Digestive Health and Nutrition, Arnold Palmer Hospital for Children, Orlando, FL.

Introduction: Children with fecal incontinence and constipation can be classified into three groups: neurogenic bowel dysfunction related to spinal cord defects (NBD), refractory constipation (RC), or anorectal malformations (ARM). The transanal irrigation (TAI) device (Peristeen®) was approved in 2012 by the FDA. This system uses a pump rather than gravity to instill water as a colonic irrigant and utilizes balloon occlusion of the rectum. Read More

J Neurogastroenterol Motil 2020 May 14. Epub 2020 May 14.

Department of biostatistics, Soonchunhyang University Seoul Hospital, Seoul, Korea.

Background/aims: We aim to evaluate associations between comorbidities, peripheral neuropathy, and spontaneous internal anal sphincter relaxation (SAR) in patients with defecatory disorders.

Methods: A patient is considered to exhibit SAR during high-resolution anorectal manometry (HR-ARM) when the nadir pressure is < 15 mmHg and the time from onset to relaxation was ≥ 15 seconds in the resting pressure frame. A case-control study was performed using HR-ARM data collected from 880 patients from January 2010 to May 2015. Read More

Arq Gastroenterol 2020 May 8. Epub 2020 May 8.

Mininvasive and Bariatric Surgery, Division of General, University of Campania "Luigi Vanvitelli", Naples, Italy.

Pelvic floor rehabilitation aims to address perineal functional and anatomic alterations as well as thoraco-abdominal mechanic dysfunctions leading to procto-urologic diseases like constipation, fecal and urinary incontinence, and pelvic pain. They require a multidimensional approach, with a significant impact on patients quality of life. An exhaustive clinical and instrumental protocol to assess defecation disorders should include clinical and instrumental evaluation as well as several clinical/physiatric parameters. Read More

J Wound Ostomy Continence Nurs 2020 May/Jun;47(3):284-290

Malgorzata Arnold, MSN, RN, CWOCN, RML, Specialty Hospital, Hinsdale, Illinois. Cecilia Yanez, BSN, RN, CWOCN, RML, Specialty Hospital, Hinsdale, Illinois. Blanca Yanez, BSN, RN, CWON, RML, Specialty Hospital, Hinsdale, Illinois.

Background: We evaluated a new bed that updates the functionality of the current air fluidized therapy (AFT)/continuous low-pressure (CLP) pressure redistributing beds. This bed was evaluated in conjunction with standard wound care interventions in a long-term acute care hospital (LTACH). The AFT feature is designed to provide pressure distribution via a fluid-like medium that forces air though millions of tiny silicone beads that float the patient's body to achieve maximum immersion and envelopment. Read More

Cochrane Database Syst Rev 2020 05 6;5:CD007471. Epub 2020 May 6.

Rehabilitation Teaching and Research Unit, Department of Medicine, University of Otago, Wellington, New Zealand.

Background: About one-third of women have urinary incontinence (UI) and up to one-tenth have faecal incontinence (FI) after childbirth. Pelvic floor muscle training (PFMT) is commonly recommended during pregnancy and after birth for both preventing and treating incontinence. This is an update of a Cochrane Review previously published in 2017. Read More

Int Braz J Urol 2020 Jul-Aug;46(4):671-672

Divisão de Urologia Feminina - Faculdade de Ciências Médicas da Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.

Neuromodulation 2020 May 4. Epub 2020 May 4.

Department of Obstetrics & Gynecology, Division of Female Pelvic Medicine and Reconstructive Surgery, University of Louisville School of Medicine, Louisville, KY, USA.

Objectives: To evaluate whether percutaneous nerve evaluation (PNE) without fluoroscopy is inferior to fluoroscopy use in women undergoing trials of sacral neuromodulation (SNM) for pelvic floor disorders (PFDs).

Materials And Methods: In an unblinded noninferiority trial, women undergoing PNE were randomized to fluoroscopy or no fluoroscopy. The primary outcome was "success" and defined as implantation of the permanent SNM device within three months of PNE. Read More

Colorectal Dis 2020 May 4. Epub 2020 May 4.

Manchester University NHS Foundation Trust, Manchester, UK.

Aim: The recto-anal inhibitory reflex (RAIR) is currently measured using manometry catheters, potentially distorting the anal canal. Anal Acoustic Reflectometry is considered a catheter free technique, primarily measuring internal anal sphincter function. We sought to determine if RAIR could be measured using AAR. Read More

J Gastrointest Surg 2020 May 4. Epub 2020 May 4.

Section of Colon and Rectal Surgery, University of Wisconsin-Madison, Madison, WI, USA.

Background: Ileal pouch function is affected by several patient factors and pouch physiology. The significance of pouch physiology on optimal pouch function has not been well characterized. The purpose of this study was to examine specific post-ileal pouch anal anastomosis (IPAA) physiologic parameters to determine impact on pouch function and quality of life. Read More

Anticancer Res 2020 May;40(5):2969-2974

Department of Surgery Pietro Valdoni, Sapienza University of Rome, Rome, Italy.

Background: Although oncological results for resection of colon cancer with inferior mesenteric artery (IMA) ligation at its origin (high tie) or immediately below the left colic artery (low tie) are similar, injury of the superior hypogastric plexus may be caused when the IMA is tied at its origin, thus impairing defecatory functions.

Aim: The importance of IMA tie location on defecatory dysfunction in patients undergoing laparoscopic sigmoidal resection without preoperative radiation therapy was studied.

Patients And Methods: From February 2013 to December 2018, 56 consecutive patients submitted to curative laparoscopic resection for stage II and III, M0, sigmoidal cancer were randomized to a high or low tie of the IMA. Read More

Tech Coloproctol 2020 May 2. Epub 2020 May 2.

Department of Colorectal Surgery, Changhai Hospital, 168 Changhai Rd, Shanghai, 200433, China.

Background: Conformal sphincter preservation operation (CSPO) is a new surgical procedure for very low rectal cancers (within 4-5 cm from the anal verge). CSPO preserves more of the dentate line and distal rectal wall and also avoids injuring nerves in the intersphincteric space, resulting in satisfactory anal function after resection. The aim of this study was to analyze the short-term surgical results and long-term oncological and functional outcomes of CSPO. Read More

Tech Coloproctol 2020 Apr 30. Epub 2020 Apr 30.

Department of Surgery B, Sheba Medical Centre, Tel Hashomer, Israel.

Background: Sacral neuromodulation (SNM) has become one of the main treatment options in patients with fecal incontinence. The aim of this study was to determine the efficacy of sacral neuromodulation in the treatment of low anterior resection syndrome (LARS).

Methods: A systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Read More

Front Oncol 2020 3;10:469. Epub 2020 Apr 3.

Department of Radiation Oncology, The Netherlands Cancer Institute, Amsterdam, Netherlands.

Late gastrointestinal (GI) toxicity after radiotherapy for prostate cancer may have significant impact on the cancer survivor's quality of life. To date, little is known about local dose-effects after modern radiotherapy including hypofractionation. In the current study we related the local spatial distribution of radiation dose in the rectum to late patient-reported gastrointestinal (GI) toxicities for conventionally fractionated (CF) and hypofractionated (HF) modern radiotherapy in the randomized HYPRO trial. Read More

Int Urogynecol J 2020 Jun 27;31(6):1063-1089. Epub 2020 Apr 27.

Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of New Mexico, Albuquerque, NM, USA.

Introduction And Hypothesis: The COVID-19 pandemic and the desire to "flatten the curve" of transmission have significantly affected the way providers care for patients. Female Pelvic Medicine and Reconstructive Surgeons (FPMRS) must provide high quality of care through remote access such as telemedicine. No clear guidelines exist on the use of telemedicine in FPMRS. Read More

Neurourol Urodyn 2020 Apr 27. Epub 2020 Apr 27.

University of California, Irvine, California.

Aims: Sacral neuromodulation (SNM) is a guideline-recommended treatment for voiding dysfunction including urgency, urge incontinence, and nonobstructive retention as well as fecal incontinence. The Axonics® System is a miniaturized, rechargeable SNM system designed to provide therapy for at least 15 years, which is expected to significantly reduce revision surgeries as it will not require replacement as frequently as the non-rechargeable SNM system. The ARTISAN-SNM study is a pivotal study designed to treat patients with urinary urgency incontinence (UUI). Read More

Medicine (Baltimore) 2020 Apr;99(17):e19824

Department of integrated Traditional and Western Medicine Anorectal, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China.

Background: Constipation is a frequent gastrointestinal symptom. It is intimately related to many diseases. 1st-line therapy can not alleviate constipation for some patients. Read More

Neurourol Urodyn 2020 Apr 23. Epub 2020 Apr 23.

Department of Urology, Vanderbilt University Medical Center, Nashville, Tennessee.

Aims: The aim of this study is to identify factors associated with urinary incontinence (UI) in a community sample of young nulligravid women.

Methods: This was a secondary analysis from a cross-sectional survey-based study of cisgender women aged 18 to 25 years recruited through a national registry of research volunteers. Participants completed validated questionnaires assessing toileting behaviors, lower urinary tract symptoms (LUTS), and bowel symptoms. Read More

Ann Med Surg (Lond) 2020 Jun 13;54:22-25. Epub 2020 Apr 13.

Department of Surgery, Faculty of Medicine, Zagazig University, Egypt.

Background: rectal prolapse can cause bleeding and fecal incontinence that affects the life quality of patients. The treatment of external rectal prolapse is surgical. There are many procedures (abdominal or perineal) that can be used depending on the severity of the condition and patient tolerability for operation. Read More

Front Oncol 2020 3;10:458. Epub 2020 Apr 3.

Center for Difficult and Complicated Abdominal Surgery, Shanghai Tenth People's Hospital Affiliated to Tongji University, Shanghai, China.

Presacral tumors are rare space occupying lesions that arise in the presacral space. The incidence of presacral tumor has been reported to be 1 in 40,000 to 63,000 patients. An even rarer occurrence is the transformation of a presacral tumor into a squamous cell carcinoma (SCC). Read More

J Laparoendosc Adv Surg Tech A 2020 Apr 21. Epub 2020 Apr 21.

Department of Pediatric Surgery, Children's Mercy-Kansas City, Kansas City, Missouri, USA.

Rectal prolapse (RP) in pediatric patients may require surgical intervention. Varying surgical approaches and heterogenous patient populations have resulted in difficulty defining surgical outcomes and superiority of technique. We sought to review our surgical and self-reported outcomes of patients who underwent laparoscopic rectopexy for idiopathic RP. Read More

Pol Przegl Chir 2020 Feb;92(2):29-33

Klinika Chirurgii Dziecięcej i Transplantacji Narządów, Instytut "Pomnik - Centrum Zdrowia Dziecka", Warszawa.

Introduction: Perianal abscess and fistula-in-ano are common findings in infants and children. The perianal abscess is usually a manifestation of a fistula-in-ano. Experience of our center indicates general lack of knowledge of the origin of the abscess and therefore, it is usually treated by incision and drainage, which leads to repeated recurrences. Read More

Ann Coloproctol 2020 Apr 20. Epub 2020 Apr 20.

Surgery department, Policlinico Umberto primo, Sapienza University of Rome, Rome, Italy.

Background: The study aims to assess the functional outcome of anal sphincter sparing procedures (SSP) with TME for anorectal adenocarcinoma.

Methods: In a multicentric, prospective, single-group study in the period between December 2012 and November 2017, 93 patients presented with anorectal adenocarcinoma were included in the study. Sixty-nine patients underwent SSP with TME. Read More

J Menopausal Med 2020 Apr;26(1):24-28

School of Nursing and Midwifery, Department of Midwifery, Ardabil University of Medical Science, Ardabil, Iran.

Objectives: Urinary incontinence (UI) and anal incontinence (AI) cause concern, social exclusion, and ultimately reduced quality of life in women. The aim of present study was to assess the prevalence and related risk factors of UI, AI, and pelvic organ prolapse (POP).

Methods: The present study recruited 340 menopausal women living in Tabriz in northwest Iran. Read More

J Clin Gastroenterol 2020 Apr 14. Epub 2020 Apr 14.

Coloproctology Unit, Clinical Management Unit of General and Gastrointestinal Surgery, Division Seville, Biomedical Research Institute (BIS), University Hospital Virgen del Rocio/CSIC University of Seville, Seville.

Objective: The development and validation of a new version of the fecal incontinence (FI) scale "Rapid Assessment Fecal Incontinence Score" (RAFIS) incorporating domains for severity, type of stool loss, and global perception of the effect of incontinence on quality of life (QoL).

Background: FI negatively impacts on QoL. Currently used incontinence questionnaires have outstanding limitations on the global assessment of the impact of the disease on QoL that patients perceive. Read More

Int J Colorectal Dis 2020 Jun 16;35(6):1149-1153. Epub 2020 Apr 16.

Department of Surgery, Ospedale GM Vannini, Istituto Figlie di San Camillo, Rome, Italy.

Purpose: The management of complex anal fistulas remains a challenge, mainly due to the considerable risk of incontinence. We compared LIFT and VAAFT in the treatment of complex anal fistulas in terms of healing time, recurrence, continence, morbidity, and postoperative pain, focusing also on patients with local abscess at the time of surgery.

Methods: We include all patients with high trans-sphincteric anal fistula even with abscess at the time of surgery. Read More

World Neurosurg 2020 Apr 13;139:132-135. Epub 2020 Apr 13.

Division of Neurosurgery, Valleywise Health Medical Center, Creighton University School of Medicine, Phoenix, Arizona, USA; Department of Surgery, University of Arizona College of Medicine - Phoenix, Phoenix, Arizona, USA. Electronic address:

Background: Chordomas are rare, slow-growing, locally aggressive, malignant tumors of the spine. Chordomas are conventionally treated with surgical resection with or without radiation. There is an absence of literature documenting the natural history of a primary sacral chordoma. Read More

Int J Colorectal Dis 2020 Jun 16;35(6):977-983. Epub 2020 Apr 16.

Department of Abdominal and General Surgery and Oncology, National Cancer Institute, 1 Santariskiu Str., LT-08406, Vilnius, Lithuania.

Purpose: Although the multimodal cancer treatment techniques have greatly improved over the years, irradiation-induced late gastrointestinal toxicity remains a great concern as it may highly affect the quality of life of a patient. The aim of this study was to define the prevalence of late gastrointestinal toxicities.

Methods: Electronic databases of Cochrane Library, Embase, Web of Science, CENTRAL and PubMed were searched until September 2019. Read More

Basic Clin Neurosci 2019 Sep-Oct;10(5):419-431. Epub 2019 Sep 1.

Physiology Research Center, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

Introduction: The present systematic review and meta-analysis aims to investigate the role of Posterior Tibial Nerve Stimulation (PTNS) in the control of Fecal Incontinence (FI).

Methods: Two independent reviewers extensively searched in the electronic databases of Medline, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, CINAHL, and Scopus for the studies published until the end of 2016. Only randomized clinical trials were included. Read More

Nihon Shokakibyo Gakkai Zasshi 2020 ;117(4):321-326

Department of Inflammatory Bowel Disease, Yokohama Municipal Citizen's Hospital.

An 86-year-old woman was diagnosed with ulcerative colitis (UC) in the 1970s. A colonoscopy performed 40 years thereafter revealed a 0-Is lesion in the upper rectum, and pathological examination showed well-differentiated adenocarcinoma. The lesion was diagnosed as colitic cancer based on the pathological findings and the 40-year interval since the diagnosis of total colitis type of UC. Read More

Br J Nurs 2020 Apr;29(7):393-398

Director of Continence Services, Cardiff and Vale University Health Board, Cardiff.

Historically, the use of colonic irrigation or transanal irrigation (TAI) has been viewed as an alternative therapy for the treatment of a wide variety of conditions not relating to bowel dysfunction, including nausea, fatigue, depression, headache, anxiety and rheumatism. However, these days it is viewed as an effective treatment in individuals who may present with bowel dysfunction and related symptoms of constipation and faecal incontinence. Such individuals would include people with neuropathic bowel disorders, conditions that affect sphincter control or bowel motility disorders. Read More

Can Fam Physician 2020 Apr;66(4):264

Geriatrician at St Paul's Hospital in Vancouver, BC.

BJOG 2020 Apr 8. Epub 2020 Apr 8.

Department of Obstetrics and Gynaecology, Isala, Zwolle, The Netherlands.

Objective: To investigate whether laparoscopic sacrohysteropexy (LSH) is non-inferior to vaginal sacrospinous hysteropexy (SSHP) in the surgical treatment of uterine prolapse.

Design: Multicentre randomised controlled, non-blinded non-inferiority trial.

Setting: Five non-university teaching hospitals in the Netherlands, one university hospital in Belgium. Read More