J Dermatol Case Rep 2015 Dec 31;9(4):103-6. Epub 2015 Dec 31.

Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands;

Background: Favre-Racouchot syndrome (nodular cutaneous elastosis with cysts and comedones) is a cutaneous disease characterized by coexistence of cysts, comedones and elastotic nodules in actinically damaged skin, typically on the face. Ultraviolet radiation plays a significant role in the development of the disease. Unilateral lesions have been described. Read More

An Bras Dermatol 2015 May-Jun;90(3 Suppl 1):185-7

Instituto Lauro de Souza Lima, Bauru, SP, BR.

The actinic comedonal plaque is characterized by papules, cysts and comedones forming a yellowish plaque in areas of chronic sun exposure skin. There are few reports in literature about this entity, considered a rare and ectopic form of Favré-Racouchot Syndrome. We report two cases of lesions located on forearms and thorax. Read More

J Dermatol 2014 Jul 8;41(7):642-4. Epub 2014 May 8.

Department of Dermatology, The 251st Hospital of Chinese PLA, Zhangjiakou, China.

Favre-Racouchot syndrome (FRS) is a disorder consisting of solar elastosis with the presence of multiple cysts and open comedones. Although the exact mechanism of the condition is not known, FRS has been specifically connected to sun exposure, smoking and radiation exposure. The histological changes present in FRS reveal an atrophic epidermis and large masses of keratinous material, causing follicular plugging, as well as solar elastotic changes and possible basophilic degeneration of connective tissue. Read More

J Cutan Med Surg 2014 Jan-Feb;18(1):72-4

Background: Favre-Racouchot syndrome is a cutaneous disease characterized by nodules, cysts, and comedones that typically develops on sun-exposed areas of the face. This syndrome most commonly affects white males between the ages of 40 and 60 years and is frequently associated with chronic sun exposure and, more recently, chronic cigarette smoking.

Objective: We report a case of Favre-Racouchot syndrome in a 39-year-old female who received 6 weeks of radiation therapy to treat a grade 3 oligodendroglioma. Read More

Pan Afr Med J 2013 6;15. Epub 2013 May 6.

Service de Dermatologie, CHU Ibn Sina, Université Med V, Souissi, Rabat, Morocco.

Pediatr Dermatol 2013 Jul-Aug;30(4):429-32. Epub 2013 Apr 8.

Pediatric Dermatology Unit, Pellegrin Children's Hospital, Bordeaux, France.

Idiopathic facial aseptic granuloma (IFAG) is a disorder that usually occurs during early childhood. Its pathogenesis remains poorly understood. The objective of this study was to investigate possible relationships between IFAG and childhood rosacea. Read More

Dermatology 2013 26;226(1):32-4. Epub 2013 Feb 26.

Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität, DE–80337 Munich, Germany.

Favre-Racouchot disease commonly presents as comedones, cysts and elastosis in the periocular region of older men. Its etiology has been linked to several exogenous factors. Here we present 2 patients with strictly unilateral manifestation of the disease and a corresponding history of predominantly one-sided chronic occupational sun exposure and smoking, making the case for the causative role of these two factors. Read More

Hautarzt 2012 Oct;63(10):766-7

Hautklinik des Universitätsklinikums Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland.

A 71-year-old man presented with disfiguring skin changes of the nose and cheek. The patient had undergone a surgery of a malignant melanoma of the right paranasal sinus and then 5 months later received radiation therapy with 60 Gy total dose to the endonasal area. Physical examination revealed elastosis, open and closed comedones, and cysts in the field of radiation exposure. Read More

Dermatol Ther 2010 Jan-Feb;23 Suppl 1:S4-6

Dermatology Unit, Cutroni-Zodda Hospital, Barcellona, Italy.

Nodular elastosis with cysts and comedones also known as Favre-Racouchot syndrome frequently occurs on actinically damaged skin of middle-aged or elderly Caucasian subjects. The disease usually affects simmetrically the skin mainly around the orbits. Treatment in the past has not been entirely satisfactory. Read More

Photodermatol Photoimmunol Photomed 2005 Oct;21(5):275-7

Department of Dermatology, Faculty of Medicine, Mersin University, Mersin, Turkey.

Favre-Racouchot disease (FRD) is a common disease characterized by solar elastosis and large open comedones and cysts. This disorder mainly affects elderly Caucasian men who have had a great deal of exposure to the sun. Patients having FRD continuously develop numerous large open comedones that could cause a cosmetic problem. Read More

Dermatology 2002 ;204(3):251

Dermatology 2001 ;202(3):270-1

Acta Derm Venereol 2000 Nov-Dec;80(6):452

Hautarzt 2000 Mar;51(3):187-91

Klinik und Poliklinik für Dermatologie, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin.

Radiation-induced acne is a rare, clinically and pathogenetically ill-defined acneiform dermatosis with special features that may occur in irradiated skin areas especially after high doses of deeply penetrating radiation. We report on a patient with an oropharyngeal carcinoma who developed severe radiation-induced acne including comedones and cysts as well as few inflammatory papules and pustules in a skin area irradiated with up to 63 gray of a 6 MeV photon beam. Acnegenic drugs may precipitate the disease; our patient was on longterm therapy with carbamazepine whose acnegenic potency is less well documented than that of testosterone or glucocorticoids. Read More

Arch Dermatol 1997 Jun;133(6):743-5

Department of Dermatology, Hospital Universitario San Carlos, Madrid, Spain.

Objective: To determine the distinction between a comedo and an infundibular cyst of Favre-Racouchot disease.

Setting: A university hospital.

Patients: From the 8 patients included in the study, 19 cysts and comedones were evaluated. Read More

Ann Dermatol Venereol 1994 ;121(10):721-3

Service de Dermatologie, Hôpital de l'Antiquaille, Lyon.

Introduction: Cutaneous elastosis with cysts and comedones (Favre-Racouchot) is one of the oldest known manifestations of helioderma. Both sides of the face are usually involved symmetrically.

Case Report: We observed a 65-year-old woman with extremely severe Favre-Racouchot disease localized exclusively on the left side of the face. Read More

Clin Exp Dermatol 1993 May;18(3):256-8

Department of Health Sciences and Dermatology, University of Osnabrück, Germany.

A 59-year-old woman with a single cuff-like plaque, consisting of multiple skin-coloured to bluish cysts and comedones on her right forearm is reported. The solitary lesion resembled, morphologically and histologically, the Favre-Racouchot syndrome. The above condition is another case of the previously described actinic comedonal plaque, which seems to be a rare entity within the spectrum of disease caused by actinic damage to the skin. Read More

Clin Exp Dermatol 1992 Sep;17(5):346-8

Department of Dermatology, General Hospital of Galicia, Santiago de Compostela, Spain.

The lichen planus follicularis tumidus was described by Belaich et al. in 1977, and we have found 13 cases published so far. We report two cases we have recently seen, one of them with multiple lesions on the head, and the other with a temporo-frontal lesion. Read More

Arch Dermatol 1982 May;118(5):365-6

J Am Acad Dermatol 1982 Jan;6(1):84-91

Pyoderma faciale is a distinctive entity. Twenty-nine patients with this process were seen in the Mayo Clinic from 1969 to 1980. Twenty-seven patients had follow-up that ranged from 1 month to 11 years, and twenty-two had follow-up of 3 years or more. Read More

Z Hautkr 1981 Feb;56(4):209-14

A new dermato-surgical method for the treatment of the Favre-Racouchot syndrome is introduced. The cysts and comedones are excised in parallel stripes by means of a small electrically driven dermatome. Thus a number of cysts is only partly cut. Read More

Arch Dermatol 1972 Feb;105(2):294-6

Arch Dermatol 1971 Jul;104(1):92-3

Vestn Dermatol Venerol 1968 Oct;42(10):73-5

Z Haut Geschlechtskr 1966 Dec;41(11):417-24

Arch Dermatol 1964 Jun;89:798-802

J Lancet 1962 May;82:204-7

Hautarzt 1961 Jun;12:265-71