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J Cosmet Dermatol 2019 Apr 1. Epub 2019 Apr 1.

Dermatology Department, Santa Casa de Curitiba Hospital, Curitiba, Brazil.

Depigmented lesions may occur as postinflammatory sequelae of subacute cutaneous lupus erythematosus (SCLE), leading to great psychosocial impact. A 53-year-old male patient presented with post-SCLE depigmented facial lesions after five years of disease stability. We proposed surgical treatment with melanocyte-keratinocyte transplantation procedure (MKTP), and after five months the patient achieved 90% repigmentation, without Koebner phenomenon (KP). Read More

J Stomatol Oral Maxillofac Surg 2019 Mar 22. Epub 2019 Mar 22.

Department of maxillofacial surgery, university institute of the face and neck, university hospital of Nice, 31, avenue de Valombrose, 06100 Nice, France. Electronic address:

Introduction: Epidermolysis bullosa (EB) is a heterogeneous group of genetic diseases characterized by cutaneous and/or mucosal fragility. Blisters can occur spontaneously or because of minor friction on facial skin or the oral cavity. The repercussions of these dermatoses complicate the management of patients during surgery; for example, wisdom teeth removal might be complicated because of the limited mouth opening and mucosal lesions may be aggravated when the area of the wisdom teeth is being explored. Read More

Postepy Dermatol Alergol 2019 Feb 22;36(1):58-62. Epub 2019 Feb 22.

Evimed Medical Center, Warsaw, Poland.

Introduction: Topical ivermectin is an effective treatment for inflammatory papulopustular rosacea in adults. Positive therapeutic effects of ivermectin due to its potential anti-inflammatory properties could be achieved in the other facial dermatoses.

Aim: To assess the efficacy of topical ivermectin 1% cream therapy in mild and moderate perioral dermatitis (PD), seborrheic dermatitis (SD) and acne vulgaris (AV). Read More

Br J Dermatol 2019 Feb 22. Epub 2019 Feb 22.

Free University of Brussels (ULB), Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM) and Service de Biostatistique et Informatique Médicale (SBIM), Route de Lennik 808/CP602, 1070, Brussels, Belgium.

Background: Facial densities of Demodex mites have been observed to be greater in patients with demodicosis and papulopustular rosacea than in healthy control patients. In patients with erythematotelangiectatic rosacea (ETR), this density has been observed to be similar to or greater than that of healthy controls. Erythema and telangiectasia, characteristics of ETR, are often observed among patients with pityriasis folliculorum, a discreet demodicosis, suggesting a possible link between these conditions. Read More

Acta Derm Venereol 2019 Feb 8. Epub 2019 Feb 8.

Department of Dermatology, Venereology and Allergy, University Medical Center and Medical Faculty Mannheim, Heidelberg University, and Center of Excellence in Dermatology, DE-68167 Mannheim, Germany.

J Drugs Dermatol 2019 01;18(1):92-102

wide variety of therapeutic options, some challenges have arisen: designing an adequate treatment plan, electing the most suitable procedures for the patient, taking into consideration the rheological characteristics of the products, considering the amount needed to achieve a natural look, but also defining the safest way to deliver the treatment. Aging of the facial structural tissue layers occurs at a different pace and the requirements for the aesthetic approach of a 30-year-old patient are different from a 60-year-old patient. A group of twelve experts in minimally invasive injectable procedures sought to identify common changes observed in different age groups in order to help in establishing a plan of treatment for patients of different ages. Read More

J Drugs Dermatol 2019 01;18(1):86-91

Background: Calcium hydroxylapatite (CaHA, Radiesse®) with integral 0.3% lidocaine (CaHA(+)) has recently been approved for use in aesthetic medicine. This study assessed the performance of CaHA(+) in subjects undergoing treatment for facial volume loss and evaluated subject and physician satisfaction. Read More

J Drugs Dermatol 2019 01;18(1):80-85

Introduction: The skin of subjects with dry, flaking, and/or scaling conditions is characterized by decreased water and skin lipids content among other findings. It is well understood that daily use of gentle cleansers and moisturizers may help to restore and maintain an optimal skin barrier function. A cohort study of patients with dry skin was developed to evaluate efficacy of daily use of a ceramide containing cleanser and cream that also has salicylic acid. Read More

J Drugs Dermatol 2019 01;18(1):75-79

Background: A device that uses microfocused ultrasound with visualization (MFU-V) is cleared in the United States and European Union as a noninvasive procedure that lifts and tightens the skin (Ultherapy® System; Merz North America, Raleigh, NC, USA). The objective of this patient survey was to obtain more in-depth information on patient satisfaction during the MFU-V treatment procedure and satisfaction with their aesthetic results. Methods: Survey participants had received MFU-V treatment and completed at least 6 months of follow-up. Read More

J Drugs Dermatol 2019 01;18(1):67-74

Objective: To study the safety, efficacy, optimal volume, and longevity of an injectable hyaluronic acid (HA) gel dermal filler to treat facial temporal fossa fat loss. Methods and materials: This open-label, single-site, 12-month study used 20 mg/mL HA gel to correct volume loss in both temples in 30 subjects. Touch-ups were allowed at week 2. Read More

J Drugs Dermatol 2019 01;18(1):59-64

Background: The safety and effectiveness of high-intensity precision radiofrequency (RF) for rejuvenating the aging neck and face, and of fractional laser therapy for treating photodamaged skin have each been previously demonstrated. Objective: To assess the effects of combining high-intensity precision RF and fractional laser therapy for treating the aging face and neck. Methods and Materials: Subjects (N=19) with Fitzpatrick skin types I to VI and mild-to-moderate solar elastosis and sun or age-related pigmentation on the face and/or neck were sequentially treated with high-intensity precision RF and fractionated laser devices during the same session. Read More

J Drugs Dermatol 2019 01;18(1):40-48

Perceptions of attractiveness can be negatively affected by submental fullness. Patients seeking to improve their submental contour have a variety of treatment options including surgical procedures, energy-based devices, and injectable treatment. The Condition of Submental Fullness and Treatment Outcomes Registry (CONTOUR) was designed to provide insights into the treatment of submental fat (SMF) in clinical practice. Read More

J Drugs Dermatol 2019 01;18(1):32-38

Background: Acne vulgaris (acne) is the most common dermatologic disease seen in a racially, geographically, politically, culturally, and socioeconomically diverse Hispanic population. Despite their growing demographics in the US, there are few studies evaluating acne treatment in this population. Potential for skin irritation and dryness, as well as pigmentary changes are key concerns. Read More

J Drugs Dermatol 2019 01;18(1):28-31

Background: Moisturizers create the illusion of smooth, soft skin by placing a temporary film over the skin surface or by imparting a transient hydration benefit that does not clinically improve the quality or appearance of skin. Objective: The objective of this 8-week study was to assess the clinically relevant effects of a 3-step facial treatment program to improve the multiple qualities of photoaged skin. Methods: Thirty-five female subjects were evaluated at baseline and after 2, 4, and 8 weeks. Read More

BMJ 2019 Jan 24;364:l2. Epub 2019 Jan 24.

Department of dermatology, Kingston Hospital, London, UK.

Facial Plast Surg 2018 Dec 28;34(6):663-664. Epub 2018 Dec 28.

Department of Oral and Maxillofacial Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China.

J Drugs Dermatol 2018 Dec;17(12):s51-55

Acne vulgaris is the most common skin condition affecting adolescents and young adults with a tremendous psychosocial impact. Its pathogenic hallmarks include follicular dyskeratosis, increased sebum production, and inflammation induced by Cutibacterium (formerly Propionibacterium) acnes within the follicle. Retinoids, derived from vitamin A, are the mainstays of acne treatment given they address the key pathogenic pathways of acne. Read More

J Drugs Dermatol 2018 12;17(12):s44-48

Acne is a common disease affecting a high percentage of the younger population. Without appropriate and effective primary prevention of scarring, post-acne scars occur in about 80-95% of all patients. Acne scarring is the result of an alteration of the healing process and it can have deep psychosocial implications for patients. Read More

J Drugs Dermatol 2018 12;17(12):s43

This supplement summarize recent advances in the scientific understanding of acne pathogenesis as it relates to effective treatment acne in patients of all skin types and describes the role of retinoids in the management of acne and effective treatment and prevention strategies for hypertrophic and atrophic acne scarring in all skin types. Read More

J Drugs Dermatol 2018 12;17(12):1310-1315

Objective: To evaluate the safety and efficacy of ISDINCEUTICS Melaclear® serum (Barcelona, Spain) on skin brightness, skin quality, and signs of facial aging. Design: This was a single-center, observational, open label, prospective clinical study. Ten healthy females (ages 30-70) with moderate signs of facial aging and moderate photodamage (hyperpigmentation and/or sun spots) were enrolled. Read More

Arch Dis Child Fetal Neonatal Ed 2019 Mar 22;104(2):F191. Epub 2018 Dec 22.

Department of Neonatology and Pediatrics, Complexo Hospitalario Universitario de A Coruña, A Coruña, Spain.

BMJ 2018 Dec 21;363:k5098. Epub 2018 Dec 21.

King's College Hospital, London, UK.

Pan Afr Med J 2018 26;30:226. Epub 2018 Jul 26.

Department of Dermatology and Venereology, Ibn Rochd University Hospital, Casablanca, Morocco.

Morbihan disease (MD) is a rare entity. Its nosography is unclear and its therapeutic management is difficult. We report a new case of MD. Read More

BMJ Case Rep 2018 Dec 3;11(1). Epub 2018 Dec 3.

Dermatology, Emek Medical Center, Afula, Israel.

Scabies is a pruritic disorder caused by Sarcoptes scabiei var. hominis infestation of the skin. Transferred by close body contact, scabies is endemic within nursing homes and among poor and overcrowded populations. Read More

Pediatr Dermatol 2019 Jan 11;36(1):e20-e22. Epub 2018 Dec 11.

Department of Dermatology, Children's of Alabama, Birmingham, Alabama.

Dermatophyte infections are exceedingly rare in neonates, possibly due to the thin stratum corneum and high sebum content of neonatal skin. Only a handful of cases of tinea faciei have been reported in neonates, with the majority of reports occuring in India. Here, we report what to our knowledge is the earliest reported presentation of tinea faciei in the United States. Read More

Eur J Dermatol 2018 Oct;28(5):727-728

Hospital de Braga, R. Sete Fontes, 4710 Braga, Portugal.

J Drugs Dermatol 2018 11;17(11):1169 - 1172

INTRODUCTION: It has been well established that patients with darker skin types (Fitzpatrick skin types IV-VI) have an increased incidence of thermal induced side effects from laser and radio frequency (RF) treatments. Complications include a higher risk of post-inflammatory hyperpigmentation, hypopigmentation, and scarring, leading to unsatisfactory clinical outcomes. Fractional technologies improve the safety when treating patients with skin of color by treating only fractions of the skin while leaving a healing reservoir of untreated skin that improves the healing process. Read More

J Drugs Dermatol 2018 11;17(11):1164 - 1168

BACKGROUND: Laser skin resurfacing has continued to evolve over the past two decades. One of the most recent advances included a hybrid fractional laser resurfacing system that can sequentially utilize two wavelengths in its delivery, non-ablative coagulation with 1470 nm, and ablative vaporization with 2940 nm. The 1470 nm laser wavelength is absorbed by water, which is ideal for creating controlled zones of coagulation to chosen depths into the dermis up to 700 micrometers. Read More

J Drugs Dermatol 2018 11;17(11):1157 - 1162

OBJECTIVE: The aim of this study was to evaluate the incidence of adverse effects following laser skin resurfacing with the microablative carbon dioxide (CO2) laser system (SmartXide DOT; DEKA, Calenzano, Italy). METHODS: A retrospective chart review was performed. Data was collected for DOT laser procedures performed at three clinical centers from 2008-2014. Read More

Front Pharmacol 2018 2;9:1254. Epub 2018 Nov 2.

Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan.

Acne vulgaris, generally resulted from overgrowth of (), is one of the most difficult-to-treat facial dermatoses and more than 90% of adolescents experienced the disease worldwide. Because the innate non-lymphoid immune system cannot effectively eliminate excessive from the skin surface, so far the therapy of acne vulgaris is still mainly dependent on antibiotic treatment. However, long-term or overdose of antibiotics may initiate microbial drug resistance and/or generate unexpected side effects that seriously hamper the use of antibiotics in the clinic. Read More

Presse Med 2018 Nov - Dec;47(11-12 Pt 1):1035-1037. Epub 2018 Oct 29.

CHU Ibn Rochd, service de dermatologie vénérologie, Casablanca, Maroc.

Eur J Dermatol 2018 Oct;28(5):701-702

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Am J Dermatopathol 2018 Nov;40(11):857-858

Division of Dermatology, Department of Medicine, University of Washington School of Medicine, Seattle, WA.

J Cosmet Dermatol 2018 Oct 5;17(5):770-774. Epub 2018 Oct 5.

Skin Laser & Surgical Specialists of NY and NJ, Hackensack, New Jersey.

Objective: To evaluate the efficacy and safety associated with use of a 589-nm solid-state laser for treatment of facial erythema.

Methods: A prospective, IRB-approved study was conducted. Participants who were interested in treatment for facial erythema were recruited. Read More

BMJ 2018 Oct 4;363:k3614. Epub 2018 Oct 4.

Department of Medicine, Neurology unit, Sultan Qaboos University Hospital, Muscat, Oman.

Med Sante Trop 2018 Aug;28(3):273-276

Unité de formation et de recherche en science de la santé. Université Ouaga 1 Joseph Ki-Zerbo (Burkina Faso).

The necrotizing and not necrotizing acute bacterial dermohypodermitis (DHD) are acute bacterial infections of tissues situated between the skin and the muscles. The localizations of the face are infrequent, and sometimes put diagnostic difficulties with other current facial dermatosis. We report in this article 4 cases of DHD of the face with skin source, hospitalized in the service of the Infectious and Tropical Diseases of the Teaching Hospital Yalgado Ouédraogo of Ouagadougou (Burkina Faso). Read More

J Drugs Dermatol 2018 Sep;17(9):1018

I read with interest the informative article by Spencer et al1 that describes the efficacious use as a novel skin lightening agent (LumaPro-C) for the treatment of patients with melasma. Read More

J Drugs Dermatol 2018 Sep;17(9):1015

When rejuvenating the face with soft tissue fillers, one must consider its structural framework, and patient specific goals/needs holistically to achieve natural results. Read More

J Drugs Dermatol 2018 Sep;17(9):1006-1009

Introduction: The evaluation of Acne using ordinal scales reflects the clinical perception of severity but has shown low reproducibility both intra- and inter-rater. In this study, we investigated if Artificial Intelligence trained on images of Acne patients could perform acne grading with high accuracy and reliabilities superior to those of expert physicians.

Methods: 479 patients with acne grading ranging from clear to severe and sampled from three ethnic groups participated in this study. Read More

J Drugs Dermatol 2018 Sep;17(9):987-996

Background: Side effects may limit the use of current tetracycline-class antibiotics for acne.

Objective: Evaluate the efficacy and safety of once-daily sarecycline, a novel, narrow-spectrum tetracycline-class antibiotic, in moderate to severe acne.

Methods: Patients 9-45 years with moderate to severe facial acne (Investigator's Global Assessment [IGA] score ≥ 3, 20-50 inflammatory and ≤ 100 noninflammatory lesions, and ≤ 2 nodules) were randomized 1:1 to sarecycline 1. Read More

J Drugs Dermatol 2018 Sep;17(9):975-981

Introduction: Air pollution continues to be a global health concern and recent studies have shown that air pollutants can cause skin damage and skin aging through several pathways that induce oxidative stress, inflammation, apoptosis, and skin barrier dysfunction. Preventive measures need to be considered to retain optimal skin health, and topical skincare products may be able to alleviate the negative effects of air pollution on skin. A randomized, double-blind, placebo-controlled clinical usage study was conducted to assess the efficacy and tolerability of a novel two-part skincare system (LVS) that was developed to provide protection against environmental skin aggressors including air pollution. Read More

J Drugs Dermatol 2018 Sep;17(9):970-973

Introduction: Melasma is a condition in which patients develop symmetric, reticulated, hyperpigmented macules and patches on the face which is thought to be the result of ultraviolet (UV) exposure and hormonal influences, although the pathogenesis is not completely understood. The topical application of epidermal growth factor has been used as a whitening agent, moisturizer, and an aid for wound healing. In this study, we explore the efficacy of topical EGF in the treatment of melasma. Read More

Cutis 2018 08;102(2):82;88

Department of Dermatology, Peking University People's Hospital, Beijing, China.

Am J Dermatopathol 2018 Oct;40(10):778-779

Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic.

Facial Plast Surg Clin North Am 2018 Nov 16;26(4):447-454. Epub 2018 Aug 16.

Private Practice, 1701 East Prospect Road, Fort Collins, CO 80525, USA. Electronic address:

Microneedling is a popular and cost-effective treatment with little down time. The application of topical agents to enhance outcomes is common practice. Microchannels created with nonthermal needling close at 4 hours to 6 hours due to fibrin plugs. Read More

Indian J Dermatol 2018 Sep-Oct;63(5):375-379

Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal, India.

Background: Awareness against abuse of topical corticosteroids (TC), especially over the face, has been going on for last 5 years in India. In spite of that we are getting lots of cases in our hospitals.

Aims: The aims of this study were to ascertain the demographics, magnitude and clinical features of TC misuse on the face among the dermatology outpatient department (OPD) attendees and to analyze its causes. Read More

Dermatol Ther 2018 11 8;31(6):e12740. Epub 2018 Oct 8.

Department of Dermatology, Hanyang University Guri Hospital, Gyeonggi-do, Republic of Korea.

Dermatol Ther 2018 09 10;31(5):e12662. Epub 2018 Sep 10.

Department of Dermatology, Third Xiangya Hospital, Central South University, Changsha, Hunan, China.

Nevus depigmentosus (ND) is a rare, congenital, nonprogressive depigmented lesion with irregular outline. To date, the few therapeutic approaches that have been developed to treat ND have yielded unsatisfactory results. We reported on a 6-month-old girl who presented with a ND on the right side of her face for 5 months. Read More

Respir Care 2018 Sep;63(9):1102-1110

Southampton General Hospital, Clinical Academic Facility, Faculty of Health Sciences, University of Southampton, Southampton, United Kingdom.

Background: The use of noninvasive ventilation masks is known to cause damage to facial skin tissue, which affects both the efficacy of the intervention and the patient's quality of life. The use of humidification with noninvasive ventilation is a common practice, but its relative role in the development of facial pressure ulcers has not been fully studied.

Methods: A crossover cohort design was used in this study, with 15 healthy volunteers. Read More

Pediatr Dermatol 2018 Nov 28;35(6):748-753. Epub 2018 Aug 28.

Division of Dermatology, Department of Medicine, University of Arizona, Tucson, Arizona.

Head-and-neck dermatitis is a variant of atopic dermatitis (AD) often seen in children and is challenging to diagnose, as it frequently overlaps with other eczematous dermatoses. Successful head-and-neck dermatitis (HND) treatment requires identification of common triggers and clinical mimickers, such as airborne dermatitis, periorificial dermatitis, and steroid-induced rosacea. Head-and-neck involvement negatively impacts quality of life and is often harder to treat than other body parts, as long-term topical corticosteroid use carries higher risks for skin atrophy on the face. Read More