- Benjamin Farahnik,
- Collin M Blattner,
- Michael B Mortazie,
- Benjamin M Perry,
- William Lear,
- Dirk M Elston
J Am Acad Dermatol 2017 Mar 13;76(3):551-558.e3. Epub 2016 Oct 13.
Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina, Charleston, South Carolina.
Hailey-Hailey disease or familial benign chronic pemphigus is a rare blistering dermatosis that is characterized by recurrent erythematous plaques with a predilection for the skin folds. For extensive Hailey-Hailey disease that is recalcitrant to conventional therapy, laser ablation, photodynamic therapy, electron beam radiotherapy, botulinum toxin type A, dermabrasion, glycopyrrolate, and afamelanotide have been reported as useful treatments, but comparative trials are lacking. This review discusses the various treatment modalities for Hailey-Hailey disease and a summary of the evidence for the most recommended treatments. Read More