1,179 results match your criteria Facial Nerve Repair


Advances in facial nerve management in the head and neck cancer patient.

Curr Opin Otolaryngol Head Neck Surg 2020 Jun 28. Epub 2020 Jun 28.

Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of California San Diego, San Diego, California, USA.

Purpose Of Review: The purpose of this review is to summarize best practices in facial nerve management for patients with head and neck cancer. In addition, we provide a review of recent literature on novel innovations and techniques in facial reanimation surgery.

Recent Findings: Although recommended when tumor ablation surgery requires facial nerve sacrifice, facial reanimation procedures are not always performed. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000641DOI Listing

Facial nerve repair utilizing intraoperative repair strategies.

Laryngoscope Investig Otolaryngol 2020 Jun 28;5(3):552-559. Epub 2020 May 28.

Department of Anatomy, Cell Biology and Physiology Indiana University School of Medicine Indianapolis Indiana USA.

Objectives: To determine whether functional and anatomical outcomes following suture neurorrhaphy are improved by the addition of electrical stimulation with or without the addition of polyethylene glycol (PEG).

Methods: In a rat model of facial nerve injury, complete facial nerve transection and repair was performed via (a) suture neurorrhaphy alone, (b) neurorrhaphy with the addition of brief (30 minutes) intraoperative electrical stimulation, or (c) neurorrhaphy with the addition electrical stimulation and PEG. Functional recovery was assessed weekly for 16 weeks. Read More

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http://dx.doi.org/10.1002/lio2.411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314485PMC

Effects of the Remaining and/or Spontaneously Regenerated Facial Axons After Hypoglossal-Facial Nerve Neurorrhaphy for Facial Paralysis.

Front Neurol 2020 29;11:413. Epub 2020 May 29.

Department of Injury and Repair, Beijing Neurosurgical Institute, Beijing, China.

The incidence of incomplete facial paralysis is now relatively higher in clinical practice, and surgical intervention is still desirable for patients with significant facial paralysis. However, the importance and usefulness of the remaining and/or spontaneously regenerated facial axons for regaining facial function when using hypoglossal-facial nerve (HN-FN) neurorrhaphy or other nerve-transferring methods to treat facial paralysis remain controversial. We designed a rat FN injury model with preservation of the anatomical structure followed by HN-FN side-to-side neurorrhaphy to investigate the effects of the remaining and/or spontaneously regenerated FN axons on restoration of facial function. Read More

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http://dx.doi.org/10.3389/fneur.2020.00413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7272673PMC

Quantitative analysis of the impact of radiotherapy on facial nerve repair with sural nerve grafting after parotid gland surgery.

J Craniomaxillofac Surg 2020 Jun 4. Epub 2020 Jun 4.

Department of Plastic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:

In this study, we aimed to reveal the long-term impact of radiotherapy on recovery of facial animation function after facial nerve repair using sural nerve grafting in patients undergoing parotid gland surgery. We reviewed the medical records of patients who did or did not undergo radiotherapy following sural nerve graft repair after parotid gland surgery. Facial function metrics, such as House-Brackmann (HB) scale scores and FACEgram measurements, were used to compare facial muscle function between groups. Read More

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http://dx.doi.org/10.1016/j.jcms.2020.05.012DOI Listing

Use of a Cervicofacial Flap in Closing Large Defects Following Wide Local Excision of Complicated Preauricular Lesions.

Ann Otol Rhinol Laryngol 2020 Jun 9:3489420932605. Epub 2020 Jun 9.

Department of Otolaryngology and Communications Sciences, Medical College of Wisconsin, Children's Hospital of Wisconsin, Milwaukee, WI, USA.

Purpose: To describe innovative surgical technique for closure of large defect following complicated preauricular cyst excision secondary to prior failed excision attempts, infections, and drainage procedures. Preauricular cysts must be widely excised including any fistulous tracts in order to reduce recurrence rates; however, the resultant large local excision poses cosmetic challenges.

Methods: Retrospective chart review of 3 patient cases who underwent excision of recurrent preauricular lesions involving cervical parotid flap closure. Read More

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http://dx.doi.org/10.1177/0003489420932605DOI Listing

Neutralizing BDNF and FGF2 injection into denervated skeletal muscle improve recovery after nerve repair.

Muscle Nerve 2020 Jun 4. Epub 2020 Jun 4.

Department of Anatomy I, University of Cologne, Germany.

Background: After facial nerve injury and surgical repair in rats, recovery of vibrissal whisking is associated with a high proportion of mono-innervated neuro-muscular junctions (NMJs). Our earlier work with Sprague Dawley (SD)/Royal College of Surgeons (RCS) rats, which are blind and spontaneously restore NMJ-monoinnervation and whisking, showed correlations between functional recovery and increase of fibroblast growth factor-2 (FGF2) and brain-derived neurotrophic factor (BDNF) in denervated vibrissal muscles.

Methods: We used normally sighted rats (Wistar), in which NMJ-polyinnervation is highly correlated with poor whisking recovery, and injected the vibrissal muscle levator labii superioris (LLS) with combinations of BDNF, anti-BDNF, and FGF2 at different postoperative periods after facial nerve injury. Read More

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http://dx.doi.org/10.1002/mus.26991DOI Listing

Use of a compact high-definition two-dimensional exoscope in surgical treatment of large vestibular schwannoma.

Chin Med J (Engl) 2020 Jun;133(11):1292-1297

Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin Neurological Institute, Key Laboratory of Post-trauma Neuro-repair and Regeneration in Central Nervous System, Ministry of Education, Tianjin Key Laboratory of Injuries, Variations and Regeneration of Nervous System, Tianjin 300052, China.

Background: Extra-corporeal video telescope operating monitor system provides a necessary instrument to perform high-precision neurosurgical procedures that could substitute or supplement the traditional surgical microscope. The present study was designed to evaluate a compact high-definition two-dimensional exoscope system for assisting in surgical removal of large vestibular schwannoma (VS), as an alternative to a binocular surgical microscope.

Methods: Patients with Koos grade 3 and grade 4 VS undergoing surgery were enrolled in this prospective cohort study between January 2013 and June 2018. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289312PMC

Assessment of axonal sprouting and motor performance after hypoglossal-facial end-to-side nerve repair: experimental study in rats.

Exp Brain Res 2020 Jun 2;238(6):1563-1576. Epub 2020 Jun 2.

Department of Anatomy I, University of Cologne, Cologne, Germany.

Hypoglossal-facial nerve anastomosis (HFA) aims to reanimate denervated mimic muscles with hypoglossal axons when the transected facial nerve is not accessible. The aim of this study was to evaluate the recovery of HFA using a "Y" tube in two variants: (1) the proximal stump of the hypoglossal nerve was entubulated to the "Y" tube (classic "Y" tube HFA) and (2) the "Y" tube was sutured to an epineurial window of a slightly damaged hypoglossal nerve (end-to-side "Y" tube HFA). A total of 48 adult female rats were divided into four groups: intact controls (group 1), sham operated (group 2), classic "Y" tube HFA (group 3) and end-to-side "Y" tube HFA (group 4). Read More

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http://dx.doi.org/10.1007/s00221-020-05835-6DOI Listing

Fetal Bovine Collagen Grafts for Repair of Tegmen Defects and Encephaloceles Via Middle Cranial Fossa Approach.

Ear Nose Throat J 2020 Apr 13:145561320906906. Epub 2020 Apr 13.

Department of Neurological Surgery, Loyola University Medical Center, Maywood, IL, USA.

To evaluate the use of commercially available allogenic dural graft materials made of fetal bovine collagen, we present an analysis of our case series with use of autologous and allogenic graft materials. Patients who underwent surgical repair of a tegmen tympani defect associated with ipsilateral conductive hearing loss and cerebrospinal fluid (CSF) otorrhea using a middle cranial fossa (MCF) approach from 2004 to 2018 at Loyola University Medical Center were included. Resolution of CSF otorrhea, audiologic outcomes, facial nerve preservation, and surgical complications was analyzed. Read More

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http://dx.doi.org/10.1177/0145561320906906DOI Listing

Repair of temporal branch of the facial nerve with novel polyglycolic acid-collagen tube: a case report of two cases.

Nagoya J Med Sci 2020 Feb;82(1):123-128

Department of Plastic and Reconstructive Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Autologous nerve transplantation has been the gold standard in the treatment of facial nerve injury, however it has not been achieved satisfactory result and needs donor sacrifice. A polyglycolic acid collagen conduit (Nerbridge, Toyobo Co., Japan) has the potential to compare to or exceed autologous nerve grafts in promoting nerve regeneration. Read More

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http://dx.doi.org/10.18999/nagjms.82.1.123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103875PMC
February 2020

Long-term electrophysiological assessment after hypoglossal-facial anastomosis.

Eur Arch Otorhinolaryngol 2020 Apr 7. Epub 2020 Apr 7.

Department of Otorhinolaryngology, Gazi University School of Medicine, Ankara, Turkey.

Purpose: To investigate and provide objective documentation of the possible differences in the axonal reinnervation process of facial muscles after hypoglossal-facial nerve anastomosis. Then, to search for the presence of the trigemino-hypoglossal reflex and determine whether it indicates better peripheral recovery.

Methods: Electrophysiological examination performed on 20 patients who had undergone VII-XII anastomosis, with follow-up periods of more than 2 years. Read More

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http://dx.doi.org/10.1007/s00405-020-05954-4DOI Listing

Involvement of orbit in maxillofacial fractures: "Evaluation of its spectrum, characteristics, and treatment in 200 patients"-Prospective study.

J Cosmet Dermatol 2020 Mar 30. Epub 2020 Mar 30.

Department of Plastic and Reconstructive Surgery, The First Hospital of Jilin University, Changchun, China.

Background: To evaluate the orbital involvement epidemiology in facial fractures, the clinical distribution and effects of orbital involvement in these patients, the frequency and nature of treatment procedures performed for these involvements, and the immediate- and intermediate-term effects of these treatment procedures.

Methods: Two hundred patients with hard tissue maxillofacial injuries were included in this study. Clinical examination was performed in-depth. Read More

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http://dx.doi.org/10.1111/jocd.13385DOI Listing
March 2020
1.000 Impact Factor

Fabrication and transplantation of chitosan-selenium biodegradable nanocomposite conduit on transected sciatic nerve: a novel study in rat model.

Neurol Res 2020 Jun 29;42(6):439-450. Epub 2020 Mar 29.

Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.

: The improvement of techniques using conduits that connects the ends of damaged nerves and guides the growth of nerve fibers between the stumps, including adoption of natural or synthetic materials still is a challenge in peripheral nerve repair. The aim of the present novel study was to fabricate and transplant chitosan-selenium biodegradable nanocomposite conduit on transected sciatic nerve in rat model.: In NORMAL group, the left sciatic nerve was exposed through a gluteal muscle incision and after careful hemostasis skin was closed. Read More

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http://dx.doi.org/10.1080/01616412.2019.1709143DOI Listing

Current landscape in motoneuron regeneration and reconstruction for motor cranial nerve injuries.

Neural Regen Res 2020 Sep;15(9):1639-1649

Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.

The intricate anatomy and physiology of cranial nerves have inspired clinicians and scientists to study their roles in the nervous system. Damage to motor cranial nerves may result from a variety of organic or iatrogenic insults and causes devastating functional impairment and disfigurement. Surgical innovations directed towards restoring function to injured motor cranial nerves and their associated organs have evolved to include nerve repair, grafting, substitution, and muscle transposition. Read More

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http://dx.doi.org/10.4103/1673-5374.276325DOI Listing
September 2020

Hypoglossal Facial Nerve Anastomosis for Post-Operative and Post-Traumatic Complete Facial Nerve Paralysis.

Open Access Maced J Med Sci 2019 Dec 29;7(23):3984-3996. Epub 2019 Jul 29.

Department of Neurosurgery, Kasr Alainy Medical School, Cairo University, Cairo, Egypt.

Aim: This study aims to evaluate the outcome of patients with complete facial paralysis following surgery to cerebellopontine angle tumours or following traumatic petrous bone fractures after reanimation by hypoglossal-facial anastomosis as regards clinical improvement of facial asymmetry and facial muscle contractility as well as complications associated with hypoglossal-facial reanimation procedure.

Methods: This thesis included a prospective study to be carried out on 15 patients with unilateral complete lower motor neuron facial paralysis (11 patients after cerebellopontine angle tumour resection and 4 patients after traumatic transverse petrous bone fracture) operated upon by end to end hypoglossal-facial nerve anastomosis in Cairo university hospitals in the period between June 2015 and January 2017.

Results: At one year follow up the improvement of facial nerve functions were as follows: Three cases (20%) had improved to House Hrackmann grade II, eleven cases (73. Read More

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http://dx.doi.org/10.3889/oamjms.2019.490DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061404PMC
December 2019

Repair of facial nerve crush injury in rabbits using collagen plus basic fibroblast growth factor.

J Biomed Mater Res A 2020 Jun 27;108(6):1329-1337. Epub 2020 Feb 27.

Department of Multidisciplinary Treatment Center, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.

Facial nerves are frequently crushed or cut during facial surgery. In this study, the feasibility of repairing facial nerves in rabbits after crush or cut off injury was evaluated using collagen conduits with A collagen-binding domain (CBD)-human basic fibroblast growth factor (bFGF). A total of 39 six-month-old New Zealand White rabbits were randomly divided into four groups of nine rabbits, and bilateral crush or cut off injuries were made on each animal's face. Read More

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http://dx.doi.org/10.1002/jbm.a.36905DOI Listing

Warthin's tumor with necrotizing tuberculous granulomatous inflammation causing severe facial nerve adhesion in parotid gland: A case report and literature review.

Medicine (Baltimore) 2020 Feb;99(7):e18763

School of Medicine, Chang Gung University, Taoyuan.

Rationale: Warthin's tumor is the second most common tumor arising from the parotid gland, but it rarely occurs concomitantly with tuberculous granulomatous inflammation with only 13 documented case reports in the English literature.

Patient Concerns: An 82-year-old woman had a left infraauricular mass for approximately 3 years that had significantly increased in size over the previous 1 month.

Diagnoses: A diagnosis of Warthin's tumor was made by ultrasonography (US)-guided core needle biopsy. Read More

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http://dx.doi.org/10.1097/MD.0000000000018763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035061PMC
February 2020

Botulinum Neurotoxins and Cancer-A Review of the Literature.

Toxins (Basel) 2020 01 5;12(1). Epub 2020 Jan 5.

Department of Neurology, Yale University School of Medicine, New Haven, CT 06519, USA.

Botulinum neurotoxins (BoNT) possess an analgesic effect through several mechanisms including an inhibition of acetylcholine release from the neuromuscular junction as well as an inhibition of specific pain transmitters and mediators. Animal studies have shown that a peripheral injection of BoNTs impairs the release of major pain transmitters such as substance P, calcitonin gene related peptide (CGRP) and glutamate from peripheral nerve endings as well as peripheral and central neurons (dorsal root ganglia and spinal cord). These effects lead to pain relief via the reduction of peripheral and central sensitization both of which reflect important mechanisms of pain chronicity. Read More

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http://dx.doi.org/10.3390/toxins12010032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020400PMC
January 2020

Third Window Syndrome: Surgical Management of Cochlea-Facial Nerve Dehiscence.

Front Neurol 2019 13;10:1281. Epub 2019 Dec 13.

Department of Neurosurgery, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, United States.

This communication is the first assessment of outcomes after surgical repair of cochlea-facial nerve dehiscence (CFD) in a series of patients. Pre- and post-operative quantitative measurement of validated survey instruments, symptoms, diagnostic findings and anonymous video descriptions of symptoms in a cohort of 16 patients with CFD and third window syndrome (TWS) symptoms were systematically studied. Observational analytic case-control study. Read More

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http://dx.doi.org/10.3389/fneur.2019.01281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6923767PMC
December 2019

[Treatment of parotid hemangioma in children].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019 Nov;33(11):1076-1080

Department of Otolaryngology Head and Neck Surgery, Kunming Children's Hospital(Children's Hospital Affiliated to Kunming Medical University), Yunnan Key Laboratory of Children's Major Disease Research, Kunming, 650228, China.

To summarize the treatment and effect of children with parotid hemangioma. Thirty-three children with parotid hemangioma were treated with drug in 22 cases, 9 of which received propranolol orally, accounting for 27%; 13 cases underwent B-ultrasound guided bleomycin injection, accounting for 40%; another 11 cases were used. The treatment of surgical removal of hemangioma, accounting for 33%. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2019.11.017DOI Listing
November 2019

Drainless resection of the submandibular gland with facial vessel preservation: A comparative study.

J Stomatol Oral Maxillofac Surg 2020 Jan 2. Epub 2020 Jan 2.

University of Istanbul, Istanbul Medical Faculty, Department of Otorhinolaryngology & Head and Neck Surgery, Istanbul, Turkey.

Objective: Resection of the submandibular gland (SMG) is a common surgery and many surgeons leave a drainage system in the surgical field. However, surgical drain may increase risk of complication and related prolonged hospitalization time. The purpose of this study was to investigate the safety of SMG resection without any surgical drainage system. Read More

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http://dx.doi.org/10.1016/j.jormas.2019.12.017DOI Listing
January 2020

Side-to-End Hypoglossal-Facial Neurorrhaphy for Treatment of Complete and Irreversible Facial Paralysis after Vestibular Schwannoma Removal by Means of a Retrosigmoid Approach: A Clinical and Anatomic Study.

World Neurosurg 2020 Apr 2;136:e262-e269. Epub 2020 Jan 2.

Department of Neurosurgery, Hospital Clínico Universitario de Valencia, Valencia, Spain; Microneurosurgery Laboratory, Department of Anatomy and Human Embriology, University Valencia, Valencia, Spain; Mayo Clinic College of Medicine and Science, Jacksonville, Florida, USA.

Background: Facial paralysis secondary to a complete and irreversible anatomic or functional lesion of the facial nerve (FN) causes severe functional and psychological disorders for the patient. A large number of surgical techniques have therefore been developed for FN repair. Our objective was to propose a surgical FN reanimation protocol for patients with irreversible anatomic or functional postsurgical injury of the FN in the cerebellopontine angle after vestibular schwannoma resection. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.12.149DOI Listing

Dual Coaptation of Facial Nerve Using Masseteric Branch of Trigeminal Nerve for Iatrogenic Facial Palsy: Preliminary Reports.

Ann Otol Rhinol Laryngol 2020 May 30;129(5):505-511. Epub 2019 Dec 30.

Department of Otolaryngology, Asan Medical Centre, College of Medicine, University of Ulsan, Seoul, Korea.

Objectives: Immediate facial nerve substitution or graft technique has been used for the repair of facial nerve defects occurring as a result of tumour dissection. However, some patients report unsatisfactory outcomes, such as difficulty in maintaining resting or smiling symmetry, due to persistent flaccid facial palsy. Here we evaluated the functional outcomes of transferring the masseteric branch of the trigeminal nerve to the facial nerve adjunct to facial nerve graft. Read More

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http://dx.doi.org/10.1177/0003489419893722DOI Listing

Platelet-rich plasma can release nutrient factors to promote facial nerve crush injury recovery in rats.

Saudi Med J 2019 Dec;40(12):1209-1217

Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial ENT Hospital Affiliated to Shandong University, Jinan, People Republic of China. E-mail.

Objectives: To evaluate the effects of platelet-rich plasma (PRP) on promoting neural repair after facial nerve compression in rats and the mechanism by which this occurs.  Methods: Adult Wistar rats (n=100) were divided into 3 groups: healthy controls, surgery-only, and surgery+PRP groups. The rats underwent nerve crush injury to establish a facial palsy model. Read More

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http://dx.doi.org/10.15537/smj.2019.12.24747DOI Listing
December 2019
0.554 Impact Factor

Longitudinal study of risk for facial nerve injury in mandibular condyle fracture surgery: marginal mandibular branch-traversing classification of percutaneous approaches.

Clin Oral Investig 2020 Apr 8;24(4):1445-1454. Epub 2019 Dec 8.

Department of Oral and Maxillofacial Surgery II, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.

Objective: This study aimed to longitudinally assess the risk of facial nerve injury (FNI) in the surgical repair of mandibular condylar neck and subcondylar fractures (CN/SCFs) and to explore its predictors.

Materials And Methods: In a retrospective cohort study, the outcome was defined as FNI at 1 week and 1, 3, and 6 months postoperatively. Potential predictors included age, sex, etiology, fracture site and pattern (dislocation/non-dislocation), concomitant facial fractures, interval to surgery, surgeons' experience, plate types, and the marginal mandibular branch-traversing approach (deep/superficial group). Read More

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http://dx.doi.org/10.1007/s00784-019-03163-wDOI Listing
April 2020
2.352 Impact Factor

Immediate compared with late repair of extracranial branches of the facial nerve: a comparative study.

Br J Oral Maxillofac Surg 2020 Feb 24;58(2):163-169. Epub 2019 Nov 24.

Facial Palsy Unit, Queen Victoria Hospital, East Grinstead, UK.

The best outcomes after injury to the facial nerve are seen after immediate direct coaptation, but in practice, this happens infrequently. We ask whether late repair (between 3 weeks and 18 months) is comparable to immediate repair. In this prospective observational study over a two-year period (2016-18), we identified 18 patients (11 male and 7 female, mean (range) age 58 (23-94) years), who had sustained extracranial injuries to the facial nerve. Read More

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http://dx.doi.org/10.1016/j.bjoms.2019.11.004DOI Listing
February 2020

Photobiomodulation in Oral Surgery: A Review.

Photobiomodul Photomed Laser Surg 2019 Dec 21;37(12):814-825. Epub 2019 Nov 21.

Radiation Sciences Research Center, Laser Research Center in Medical Sciences, AJA University of Medical Sciences, Tehran, Iran.

This article presents a review of current data on the applications of photobiomodulation (PBM) in the field of oral and maxillofacial surgery (OMFS), to guide future research. Photobiomodulation therapy (PBMT) has been reported to be effective for various postoperative conditions, including pain relief, improvement of mastication, neurosensory recovery, and wound healing. There is a need for identifying the therapeutic irradiation windows for these conditions, based upon the available literature. Read More

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http://dx.doi.org/10.1089/photob.2019.4712DOI Listing
December 2019

Chimeric Vastus Lateralis and Anterolateral Thigh Flap for Restoring Facial Defects and Dynamic Function following Radical Parotidectomy.

Plast Reconstr Surg 2019 11;144(5):853e-863e

Camperdown, Wollongong, and Liverpool, New South Wales, Australia From the Faculty of Medicine and the Central Clinical School, University of Sydney; Department of Head and Neck Surgery and Sydney Facial Nerve Service, The Chris O'Brien Lifehouse; the Illawarra Health and Medical Research Institute; and the Centre for Oncology Education and Research Translation.

Background: Extirpation of malignant tumors of the parotid results in creation of a complex facial defect often in combination with facial nerve palsy. This study presents the authors' experience using vastus lateralis muscle as a chimeric flap with anterolateral thigh flap to allow both soft-tissue reconstruction and dynamic reanimation in radical parotidectomy.

Methods: A retrospective review of the medical records of cancer patients who had undergone radical parotidectomy and reconstruction using a chimeric vastus lateralis and anterolateral thigh flap between March of 2013 and May of 2017 was performed using the Sydney Head and Neck Cancer Institute database. Read More

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http://dx.doi.org/10.1097/PRS.0000000000006183DOI Listing
November 2019

CICAFAST: comparison of a biological dressing composed of fetal fibroblasts and keratinocytes on a split-thickness skin graft donor site versus a traditional dressing: a randomized controlled trial.

Trials 2019 Oct 28;20(1):612. Epub 2019 Oct 28.

Clinical Investigation Centre CIC1413, Nantes INSERM and CHU Nantes, 5, allée de l'île Gloriette, 44093, Nantes Cedex 1, France.

Background: Wound repair is one of the most complex biological processes of human life. Allogeneic cell-based engineered skin substitutes provide off-the-shelf temporary wound coverage and act as biologically active dressings, releasing growth factors, cytokines and extracellular matrix components essential for proper wound healing. However, they are susceptible to immune rejection and this is their major weakness. Read More

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http://dx.doi.org/10.1186/s13063-019-3718-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819456PMC
October 2019
1 Read

Simplified Lateral Brow Lift under Local Anesthesia for Correction of Lateral Hooding.

Plast Reconstr Surg Glob Open 2019 Jun 12;7(6):e2098. Epub 2019 Jun 12.

Northwestern University Feinberg School of Medicine, Division of Plastic and Reconstructive Surgery, Chicago, Ill.

Background: A limited incision lateral brow lift has been described as an alternative to the endoscopic or the bicoronal approaches. The senior author has developed a safe and effective lateral brow lift technique that can be performed in an office setting under local anesthesia.

Methods: We retrospectively reviewed 150 consecutive patients who underwent a brow lift by the senior author (TAM). Read More

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http://Insights.ovid.com/crossref?an=01720096-900000000-9791
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http://dx.doi.org/10.1097/GOX.0000000000002098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635213PMC
June 2019
11 Reads

Microvascular decompression in patients with hemifacial spasm.

Brain Behav 2019 11 15;9(11):e01432. Epub 2019 Oct 15.

Logistics College of the Chinese People's Armed Police Force, Tianjin, China.

Purpose: To study blood pressure alterations after microvascular decompression (MVD) surgery in patients with hemifacial spasm (HFS).

Methods: A retrospective study was performed to review HFS patients who received MVD surgery between January 2014 and December 2016. Vessels that were considered to be responsible for HFS were determined by reviewing the brain magnetic resonance imaging, magnetic resonance angiography, and surgical video. Read More

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http://dx.doi.org/10.1002/brb3.1432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851818PMC
November 2019

Reconstruction of a Chronic Volkmann Contracture following Forearm Revascularization with Burkhalter's Procedure and Fractional Flexor Tendon Lengthening after a Failed Stiles-Bunnell Transfer.

J Hand Microsurg 2019 Oct 17;11(Suppl 1):S36-S41. Epub 2019 Apr 17.

Department of Plastic, Reconstructive and Maxillo-Facial Surgery, and Burn Unity, Centro Hospitalar de São João, Porto Medical School, Porto, Portugal.

Volkmann ischemic contracture is a cause of limb dysfunction that can lead to varying amounts of limb deformity, stiffness, and paralysis. Several procedures have been used to improve limb function in these patients. An 11-year-old male patient sustained a domestic accident with a glass door, resulting in a severe soft tissue trauma to his proximal third of the right forearm with damage to flexor muscles and tendons, complete section of median and ulnar nerves, and radial and ulnar arteries. Read More

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http://dx.doi.org/10.1055/s-0039-1683457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791807PMC
October 2019

Bacterial cellulose tubes as a nerve conduit for repairing complete facial nerve transection in a rat model.

Eur Arch Otorhinolaryngol 2020 Jan 8;277(1):277-283. Epub 2019 Oct 8.

Department of Otorhinolaryngology-Head and Neck Surgery, Pendik Training and Research Hospital, Marmara University Medical Faculty, Istanbul, Turkey.

Purpose: Functionality of the facial nerve is cosmetically important. While many techniques have been investigated, early and effective treatment for traumatic facial nerve paralysis remains challenging. Here, we aim to examine bacterial cellulose (BC) as a new tubularization material for improving facial nerve regeneration. Read More

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http://dx.doi.org/10.1007/s00405-019-05637-9DOI Listing
January 2020
1 Read

Common Complications in Rhytidectomy.

Facial Plast Surg Clin North Am 2019 Nov 4;27(4):519-527. Epub 2019 Sep 4.

Santa Barbara Plastic Surgery Center, 222 West Pueblo Street, Suite A, Santa Barbara, CA 93105, USA.

Complications of rhytidectomy are well known, yet often preventable. A thorough preoperative history and physical along with realistic patient expectations provide the surgeon and patient with insight into potential complications and postoperative management. Understanding of surgical pitfalls and avoidance are crucial in beginning to manage facelift complications. Read More

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http://dx.doi.org/10.1016/j.fsc.2019.07.008DOI Listing
November 2019

Facial nerve repair: the impact of technical variations on the final outcome.

Eur Arch Otorhinolaryngol 2019 Dec 19;276(12):3301-3308. Epub 2019 Sep 19.

Department of Otorhinolaryngology, La Paz University Hospital, IdiPAZ Research Institute, Paseo La Castellana #261, 28046, Madrid, Spain.

Objectives: To analyze the outcome of facial nerve (FN) reconstruction, the impact of technical variations in different conditions and locations, and the importance of additional techniques in case of suboptimal results.

Study Design: Retrospective study.

Setting: University-based tertiary referral center. Read More

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http://dx.doi.org/10.1007/s00405-019-05638-8DOI Listing
December 2019
3 Reads

Results Of Immediate Facial Nerve Reconstruction In Patients Undergoing Parotid Tumour Resection.

J Ayub Med Coll Abbottabad 2019 Jul-Sep;31(3):340-345

Plastic Surgery Department, Shifa International Hospital, Islamabad, Pakistan.

Background: Facial nerve is usually sacrificed in total parotidectomy. The objective of this study is to present results of immediate reconstruction of facial nerve in total parotidectomy cases where facial nerve is sacrificed.

Methods: This is a prospective study done in patients who had total parotidectomy including facial nerve and immediate reconstruction was done with inter-positional nerve grafts (sural n=12 and greater auricular n=10) from December 2017 till February 2018 by single surgeon (MR). Read More

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January 2020
2 Reads

An Anatomic Variant of the Ansa Cervicalis Precluding Its Use as a Donor Nerve.

Ann Otol Rhinol Laryngol 2020 Jan 11;129(1):78-81. Epub 2019 Sep 11.

Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, MA, USA.

Background: The ansa cervicalis is useful for cranial nerve repair, and may be harvested without apparent morbidity. Herein we report an unusual and surgically relevant anatomic variant of the ansa cervicalis.

Methods: An adult male with left parotid adenoid cystic carcinoma underwent parotidectomy with upper-division facial nerve resection and planned interposition repair using the ansa cervicalis. Read More

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http://dx.doi.org/10.1177/0003489419875975DOI Listing
January 2020
2 Reads

Salomone et al did not induce PEG-fusion repair of severed rat facial nerves.

Head Neck 2019 10 9;41(10):3737-3739. Epub 2019 Aug 9.

Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1002/hed.25894DOI Listing
October 2019

Outcome measures of facial nerve regeneration: A review of murine model systems.

Ann Anat 2020 Jan 5;227:151410. Epub 2019 Aug 5.

University of Rochester Medical Center, 601 Elmwood Avenue, Box 661, Rochester, NY, USA.

Animal models of nerve function have been subject to extensive study in order to understand and investigate methods which may improve axon regeneration and promote functional outcomes following nerve injury and repair. As the facial nerve is a cranial nerve, there is mounting evidence that cranial nerve regeneration differs from peripheral, and outcome models specifically addressing the facial nerve are required. Murine models are the most commonly utilized, with a variety of methods employed to measure the actions of whisking, eye closure, or ear movement as indicators of facial nerve regeneration. Read More

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http://dx.doi.org/10.1016/j.aanat.2019.07.011DOI Listing
January 2020
3 Reads

Outcomes of 360° Osteotomy in the Cervicothoracic Spine (C7-T1) for Congenital Cervicothoracic Kyphoscoliosis in Children.

J Bone Joint Surg Am 2019 Aug;101(15):1357-1365

Department of Orthopedics, Peking Union Medical College Hospital, Beijing, People's Republic of China.

Background: There have been many reports on the treatment of congenital kyphoscoliosis. However, congenital deformities in the cervicothoracic spine (C7-T1) have not been well described because of the rarity of these conditions.

Methods: The medical records and imaging studies of 25 children who were treated with 360° osteotomy for congenital deformities in the cervicothoracic spine (C7-T1) at a mean age of 11. Read More

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http://dx.doi.org/10.2106/JBJS.18.01428DOI Listing
August 2019
5 Reads
5.280 Impact Factor

Two of a kind: transmissible Schwann cell cancers in the endangered Tasmanian devil (Sarcophilus harrisii).

Cell Mol Life Sci 2020 May 2;77(9):1847-1858. Epub 2019 Aug 2.

Menzies Institute for Medical Research, University of Tasmania, 17 Liverpool Street, Hobart, TAS, 7000, Australia.

Devil facial tumour disease (DFTD) comprises two genetically distinct transmissible cancers (DFT1 and DFT2) endangering the survival of the Tasmanian devil (Sarcophilus harrisii) in the wild. DFT1 first arose from a cell of the Schwann cell lineage; however, the tissue-of-origin of the recently discovered DFT2 cancer is unknown. In this study, we compared the transcriptome and proteome of DFT2 tumours to DFT1 and normal Tasmanian devil tissues to determine the tissue-of-origin of the DFT2 cancer. Read More

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http://dx.doi.org/10.1007/s00018-019-03259-2DOI Listing
May 2020
5 Reads

Use of the facelift incision for excision of non-tuberculous mycobacterial lymphadenitis in children.

Int J Pediatr Otorhinolaryngol 2019 Oct 10;125:182-186. Epub 2019 Jul 10.

Tufts Medical Center, Department of Otolaryngology-Head and Neck Surgery, Boston, MA, USA; Department of Pediatric Otolaryngology-Head and Neck Surgery and Pediatric Facial Plastic Surgery, Floating Hospital for Children at Tufts Medical Center, Boston, MA, USA. Electronic address:

Objectives: To present cases of pediatric periparotid nontuberculous mycobacterial lymphadenitis excised through a facelift incision in order to review the advantages of this approach to parotidectomy. We also aim to discuss scenarios in which to forgo the facelift incision in favor of a traditional modified Blair incision.

Methods: Retrospective series of seven consecutive patients who underwent parotidectomy for nontuberculous mycobacterial lymphadenitis between 2013 and 2018. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.07.005DOI Listing
October 2019
3 Reads

Nonmicrosurgical Grafting for Facial Nerve Branches with Permanent Sensational Functional Outcome.

Plast Reconstr Surg Glob Open 2019 May 16;7(5):e2195. Epub 2019 May 16.

Onco-Surgery Department, AL-Azhar University, Cairo, Egypt.

A 49-year-old man underwent intraoperatively modified procedure from superficial to radical parotidectomy with excision of the facial nerve 4 branches, temporal, zygomatic, buccal, and mandibular. We have dissected and harvested the branches of the great auricular nerve to repair the defects of the temporal, zygomatic, buccal, and mandibular nerves without microsurgery aid. The aims of the repair were just to mark the nerve endings, to try autologous grafting, and to avoid neuroma(s) formation, although neuroma(s) formations from motor nerves are rare. Read More

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http://dx.doi.org/10.1097/GOX.0000000000002195DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571312PMC
May 2019
2 Reads

Single-stage reconstruction of third-degree perineal lacerations in horses under general anesthesia: Utrecht repair method.

Vet Surg 2019 Oct 7;48(7):1299-1308. Epub 2019 Jul 7.

Equine Department, Equine Veterinary Clinic Emmeloord, Emmeloord, The Netherlands.

Objective: To describe perioperative management, surgical procedure, and outcome in mares with third-degree perineal lacerations (TDPL) treated with a single-stage repair, the Utrecht repair method (URM).

Study Design: Retrospective study.

Animals: Twenty mares with TDPL. Read More

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http://dx.doi.org/10.1111/vsu.13280DOI Listing
October 2019
3 Reads

An Anatomical Feasibility Study Using a Great Auricular Nerve Graft for Ipsilateral Inferior Alveolar Nerve Repair.

J Craniofac Surg 2019 Nov-Dec;30(8):2625-2627

Seattle Science Foundation, Seattle, WA.

The great auricular nerve (GAN) has been used for trigeminal and facial nerve repair and the inferior alveolar nerve (IAN) are often sacrificed during segmental mandibulectomy. To our knowledge, only 1 case report has discussed IAN repair using GAN after segmental mandibulectomy. The goal of this study is to clarify the feasibility of using GAN for IAN repair. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005739DOI Listing
January 2020
11 Reads

Risk factors for hypesthesia after repair of facial fractures.

Oral Surg Oral Med Oral Pathol Oral Radiol 2019 Oct 16;128(4):366-372. Epub 2019 May 16.

Department of Oral and Maxillofacial Surgery, School of Dentistry, Pusan National University, Yangsan, Korea; Institute of Translational Dental Sciences & Dental Research Institute, Pusan National University, Yangsan, Korea. Electronic address:

Objective: The aim of this study was to investigate the incidence of hypesthesia in patients with facial bone fractures and to identify the relationships between posttraumatic hypesthesia and risk factors, including general and fracture-related characteristics.

Study Design: A total of 437 patients who underwent surgery for facial bone fractures were included. Clinical neurosensory testing was performed at different time points (immediately after trauma and 1 week, 1 month, and 6 months after surgery). Read More

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http://dx.doi.org/10.1016/j.oooo.2019.05.003DOI Listing
October 2019
7 Reads

Acetyl-L-carnitine for the treatment of diabetic peripheral neuropathy.

Cochrane Database Syst Rev 2019 06 15;6:CD011265. Epub 2019 Jun 15.

Department of Internal Medicine, Universidade Federal de São Paulo, Rua Borges Lagoa, 1065/110, São Paulo, São Paulo, Brazil, 04038-032.

Background: Diabetic peripheral neuropathy (DPN) is a common and severe complication that affects 50% of people with diabetes. Painful DPN is reported to occur in 16% to 24% of people with diabetes. A complete and comprehensive management strategy for the prevention and treatment of DPN, whether painful or not, has not yet been defined. Read More

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http://dx.doi.org/10.1002/14651858.CD011265.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6953387PMC
June 2019
5 Reads

Facial reanimation: an update on nerve transfers in facial paralysis.

Curr Opin Otolaryngol Head Neck Surg 2019 Aug;27(4):231-236

Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology - Head and Neck Surgery, Rush University Medical Center, Chicago, Illinois, USA.

Purpose Of Review: The aim of this article is to review the recent literature on nerve transfers in facial paralysis. The discussion focuses on direct nerve repair and three types of nerve transfers, cross facial nerve graft, hypoglossal, and masseter nerve transfers.

Recent Findings: Masseteric nerve transfers have a high probability of creating significant movement, although tone is poor. Read More

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http://dx.doi.org/10.1097/MOO.0000000000000543DOI Listing
August 2019
13 Reads