1,112 results match your criteria Facial Nerve Repair


Segmental Gracilis Muscle Transplantation for Midfacial Animation in Möbius Syndrome: A 29-Year Experience.

Plast Reconstr Surg 2019 Mar;143(3):581e-591e

Toronto and Ottawa, Ontario, Canada From the Division of Plastic and Reconstructive Surgery, The Hospital for Sick Children; the Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Toronto; and the Faculty of Medicine, University of Ottawa.

Background: Möbius syndrome is a complex congenital disorder of unclear cause involving multiple cranial nerves and typically presenting with bilateral facial and abducens nerves palsies. At The Hospital for Sick Children, Toronto, Ontario, Canada, microneurovascular transfer of free-muscle transplant is the procedure of choice for midfacial animation. The primary aim of this study was to investigate surgical outcomes of the procedure in terms of complications, secondary revisions, and smile excursion gains. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005368DOI Listing
March 2019
1 Read

Facial Nerve Trauma: Clinical Evaluation and Management Strategies.

Plast Reconstr Surg 2019 Feb 14. Epub 2019 Feb 14.

Department of Plastic and Reconstructive Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.

The field of facial paralysis requires the reconstructive surgeon to apply a wide spectrum of reconstructive and aesthetic principles utilizing a comprehensive array of surgical tools, including microsurgery, peripheral nerve surgery, and aesthetic facial surgery on the road to optimize patient outcomes. The distinct deficits created by different anatomic levels of facial nerve injury require a fundamental understanding of facial nerve anatomy. Palsy duration, followed by location and mechanism, will determine mimetic muscle salvageability, either via direct repair, grafting, or nerve transfers, while longer palsy durations will necessitate introducing a new neuromuscular unit, whether by muscle transfer or free functional muscle transplant. Read More

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http://dx.doi.org/10.1097/PRS.0000000000005572DOI Listing
February 2019
2 Reads

Clinical Features, Intradural Transcavernous Surgical Management, and Outcomes of Giant Cavernous Sinus Hemangiomas: A Single-Institution Experience.

World Neurosurg 2019 Feb 5. Epub 2019 Feb 5.

Department of Neurosurgery, Beijing Tian Tan Hospital, Capital Medical University, Beijing, China.

Background: Cavernous sinus hemangiomas (CSHs) are rare vascular tumors. Stereotactic radiosurgery is an effective treatment for small CSHs. The optimal treatment for giant CSHs is controversial. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.165DOI Listing
February 2019
3 Reads
2.417 Impact Factor

Genetical modification on adipose-derived stem cells facilitates facial nerve regeneration.

Aging (Albany NY) 2019 Feb;11(3):908-920

Department of Plastic Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.

Adipose-derived stem cells (ASCs) have a demonstrative therapeutic potential in aging-associated facial nerve regeneration, in which ASCs work as a source of Schwann cells therapy as an alternative to autologous nerve grafts. However, the transplantation of ASCs may induce local fibrosis, which causes inferior outcome. Here, we aimed to use genetic modification approaches to reduce the fibrogenic properties of ASCs to improve their therapeutic effects on facial nerve regeneration. Read More

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http://dx.doi.org/10.18632/aging.101790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382422PMC
February 2019
1 Read

Review: Bioengineering approach for the repair and regeneration of peripheral nerve.

Bioact Mater 2019 Mar 10;4(1):107-113. Epub 2018 Oct 10.

Department of Orthopaedic Surgery, University of Connecticut Health, 263Farmington Ave., Farmington, CT 06030, USA.

Complex craniofacial surgeries of damaged tissues have several limitations, which present complications and challenges when trying to replicate facial function and structure. Traditional treatment techniques have shown suitable nerve function regeneration with various drawbacks. As technology continues to advance, new methods have been explored in order to regenerate damaged nerves in an effort to more efficiently and effectively regain original function and structure. Read More

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http://dx.doi.org/10.1016/j.bioactmat.2018.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351356PMC

Incidence Pattern of Bear-Inflicted Injuries to the Maxillofacial Region-Soft and Hard Tissue Injuries, Their Management, and Sequelae.

J Oral Maxillofac Surg 2019 Jan 3. Epub 2019 Jan 3.

Postgraduate Student, Department of Oral and Maxillofacial Surgery, H.P. Govt. Dental College and Hospital, Shimla, India.

Purpose: The aims of the study were to elucidate the incidence pattern of bear-inflicted facial injuries and to document soft and hard tissue injuries, their management, and complications.

Materials And Methods: A prospective study was performed of 21 bear-associated injuries sustained to the facial region. Most patients were young to middle age and most were male. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391183139
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http://dx.doi.org/10.1016/j.joms.2018.12.029DOI Listing
January 2019
8 Reads

Convergent end-to-end neurorrhaphy: An alternative technique for dual innervation of the gastrocnemius muscle in rats.

Microsurgery 2019 Jan 31. Epub 2019 Jan 31.

Plastic Surgery Department, Hospital das Clínicas, University of São Paulo, São Paulo, São Paulo, Brazil.

Introduction: Muscle contraction generated by electrical impulses simultaneously originating from two different neural sources may be an interesting treatment alternative for long term facial palsy. An experimental model was designed to compare single and dual innervation of the gastrocnemius muscle (GM) in rats.

Methods: Fifty adult Wistar rats underwent transection of their right peroneal nerve and were divided into five groups (n = 10): control (C), tibial nerve section (TS), tibial nerve primary end-to-end neurorrhaphy (PEE), tibial nerve primary repair associated with end-to-side peroneal-to-tibial nerve transfer (PRES), and tibial nerve repair by convergent end-to-end (CEE) neurorrhaphy between the proximal stumps of the tibial and peroneal nerves to the distal stump of the tibial nerve. Read More

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http://dx.doi.org/10.1002/micr.30433DOI Listing
January 2019
2 Reads

The Great Auricular Nerve: Anatomical Study with Application to Nerve Grafting Procedures.

World Neurosurg 2019 Jan 28. Epub 2019 Jan 28.

Seattle Science Foundation, Seattle, Washington, USA; Department of Anatomical Sciences, St. George's University, St. George's, Grenada.

Background: When it comes to autogenous nerve grafting, the sural and great auricular nerve (GAN) are the 2 nerves predominately used for trigeminal and facial nerve repair. Arising from the second and third cervical ventral rami, the GAN emerges from the posterior border of the sternocleidomastoid coursing superiorly and anteriorly toward the ear.

Methods: Eleven sides from 5 Caucasian and 1 Asian cadaveric heads (all fresh-frozen) were used. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.087DOI Listing
January 2019
1 Read

Patient Perspective in the Management of Zygomatic Fractures.

Ann Maxillofac Surg 2018 Jul-Dec;8(2):239-246

Department of Orthodontics and Dentofacial Orthopaedics, Institute of Dental Sciences, Siksha 'O' Anusandhan University, Bhubaneswar, Odisha, India.

Background: A clinical study was undertaken on the management of zygomatic complex fractures using various surgical approaches in the Department of Oral and Maxillofacial surgery during the past 3 years.

Aims: The aim of this study is to evaluate the versatility of various surgical approaches.

Materials And Methods: A total of 15 cases were selected following a clinical and radiological examination of fractures of the zygomatic complex. Read More

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http://www.amsjournal.com/text.asp?2018/8/2/239/248604
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http://dx.doi.org/10.4103/ams.ams_85_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327811PMC
January 2019
6 Reads

Fascicular turnover flap in the reconstruction of facial nerve defects: an experimental study in rats.

J Plast Surg Hand Surg 2019 Jan 24:1-6. Epub 2019 Jan 24.

a Department of Plastic Surgery , Oita University Hospital , Oita , Japan.

The purpose of this study was to assess the utility of a fascicular turnover flap for facial nerve repair and to investigate its possible application in the field of facial nerve repair using a rat model of facial paralysis. Twenty-four Wistar rats were used in this study. A left vibrissal muscle palsy model was established via excision of the buccal and marginal branches through a periauricular incision. Read More

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http://dx.doi.org/10.1080/2000656X.2018.1562458DOI Listing
January 2019
1 Read

Facial Nerve Injury and Repair: A Practical Review for Cutaneous Surgery.

Dermatol Surg 2019 Mar;45(3):340-357

Surgical Dermatology Group, Vestavia Hills, Alabama.

Background: The facial nerve and its branches are at risk of injury during dermatologic surgery. Few publications in the dermatologic literature discuss facial nerve injury and management.

Objective: To review facial nerve injury and management, including static and dynamic repair techniques, and to review outcomes in facial nerve reconstruction. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001773DOI Listing
March 2019
1 Read

Sensory Restoration of the Facial Region.

Ann Plast Surg 2018 Dec 13. Epub 2018 Dec 13.

From the Department of Plastic Surgery, University of Tennessee Health Science Center, Memphis, TN.

Normal sensitivity of the face is very important for preserving its integrity and function as an efferent source of information for the brain. The trigeminal nerve, which is the largest cranial nerve, conducts most of facial sensory function through its 3 branches: the ophthalmic nerve (V1), the maxillary nerve (V2), and the mandibular nerve (V3). The trigeminal nerve may be damaged by a variety of etiologies including inflammatory disorders, brain tumor resection, trauma, iatrogenic injury, or congenital anomalies. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001635DOI Listing
December 2018
12 Reads

Trochlear Nerve Repair during Retrosigmoid Suprameatal Approach for Petrotentorial Meningioma: Operative Video.

J Neurol Surg B Skull Base 2018 Dec 1;79(Suppl 5):S404-S406. Epub 2018 Oct 1.

Department of Neurosurgery, Tokyo Medical University, Tokyo, Japan.

When operating on difficult skull base lesions, it is essential to be able to handle unexpected intraoperative findings or troubles, while achieving maximal lesion removal and minimal functional deficit. This video demonstrates a case of trochlear nerve repair that was performed during the retrosigmoid suprameatal approach for treatment of a petrotentorial meningioma, extending into the Meckel's cave. The patient is a 47-year-old woman with a right petrotentorial meningioma, extending into the Meckel's cave. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1669967
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http://dx.doi.org/10.1055/s-0038-1669967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240355PMC
December 2018
10 Reads

CXCL12 has therapeutic value in facial nerve injury and promotes Schwann cells autophagy and migration via PI3K-AKT-mTOR signal pathway.

Int J Biol Macromol 2019 Mar 2;124:460-468. Epub 2018 Nov 2.

Department of Neurosurgery, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China. Electronic address:

Facial nerve injury is a clinically common disease accompanied by demyelination of damaged nerves. The remyelination of damaged nerves and the unsatisfactory function recovery are problems that have been plaguing people for a long time. The role that CXCL12 plays after facial nerve injury remains unknown. Read More

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http://dx.doi.org/10.1016/j.ijbiomac.2018.10.212DOI Listing

Comparison of the application of artificial ossicles and autologous ossicles in the reconstruction of a damaged ossicular chain.

Authors:
L Zhao J Li S Gong

J Laryngol Otol 2018 Oct;132(10):885-890

Department of Otolaryngology,Head and Neck Surgery,Beijing Friendship Hospital,Capital Medical University,China.

Objective: To evaluate the therapeutic effect that the titanium partial ossicular reconstruction prosthesis and autologous ossicles have on hearing loss after reconstruction of a damaged ossicular chain.

Methods: Forty-two medical records of treatments carried out from 2013 to 2015 for ossicular chain damage with facial nerve paralysis due to temporal bone fractures were reviewed. The study assessed: causes of damage, pre-operative pure tone audiometry findings, types of intra-operative ossicular chain damage, intra-operative ossicular chain repair methods (titanium partial ossicular reconstruction prosthesis or autologous ossicles) and post-operative pure tone audiometry results. Read More

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http://dx.doi.org/10.1017/S0022215118001627DOI Listing
October 2018
7 Reads

Stem Cells from Human Exfoliated Deciduous Teeth (SHED) Differentiate in vivo and Promote Facial Nerve Regeneration.

Cell Transplant 2019 Jan 31;28(1):55-64. Epub 2018 Oct 31.

1 Department of Ophthalmology and Otolaryngology, University of Sao Paulo, School of Medicine, Brazil.

Post-traumatic lesions with transection of the facial nerve present limited functional outcome even after repair by gold-standard microsurgical techniques. Stem cell engraftment combined with surgical repair has been reported as a beneficial alternative. However, the best association between the source of stem cell and the nature of conduit, as well as the long-term postoperative cell viability are still matters of debate. Read More

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http://dx.doi.org/10.1177/0963689718809090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322138PMC
January 2019
1 Read

End-to-Side Nerve Repair: Current Concepts and Future Perspectives.

Ann Plast Surg 2018 Dec;81(6):736-740

Department of Plastic Surgery, University of Balamand, Beirut, Lebanon.

Peripheral nerves injuries are extremely debilitating and have been a perennial challenge to the reconstructive surgeon. End-to-side (ETS) neurorrhaphy is a potential strategy for treating nerve lesions without usable proximal nerve stump. A number of interesting clinical and experimental studies have been carried out on ETS nerve repair during the first years of the 20th century. Read More

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http://dx.doi.org/10.1097/SAP.0000000000001663DOI Listing
December 2018
4 Reads

Fallopian Canal Meningocele with Spontaneous Cerebrospinal Fluid Otorrhea: Case Report and Systematic Review of the Literature.

World Neurosurg 2019 Feb 13;122:e285-e290. Epub 2018 Oct 13.

Department of Otorhinolaryngology, Mayo Clinic School of Medicine, Rochester, Minnesota, USA; Department of Neurosurgery, Mayo Clinic School of Medicine, Rochester, Minnesota, USA. Electronic address:

Objective: To present a case of spontaneous cerebrospinal fluid (CSF) otorrhea from a fallopian canal meningocele involving the geniculate fossa and review all cases of fallopian canal CSF leak reported in the literature with discussion of management and outcomes.

Methods: A 53-year-old woman with history of morbid obesity and hypertension presented to a tertiary care referral center with unilateral high-volume CSF otorrhea. High-resolution temporal bone computed tomography demonstrated significant dilatation of the geniculate fossa. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.10.021DOI Listing
February 2019
11 Reads

Management of Flaccid Facial Paralysis of Less Than Two Years' Duration.

Otolaryngol Clin North Am 2018 Dec 5;51(6):1093-1105. Epub 2018 Oct 5.

Division of Facial Plastic and Reconstructive Surgery, Department of Otorhinolaryngology-Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

Flaccid facial paralysis results in disfiguring facial changes. The treatment of flaccid facial paralysis is complex and treatment approaches should be determined based on duration and the causes of paralysis, status and accessibility of the affected facial nerve, medical comorbidities, and patient-specific goals. Although primary nerve repair is the preferred treatment strategy when possible, nerve substitution procedures are the mainstay of treatment for patients with flaccid facial paralysis of less than 2 years duration. Read More

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http://dx.doi.org/10.1016/j.otc.2018.07.006DOI Listing
December 2018
1 Read

Neuroendoscopic Resection of Trigeminal Schwannoma in the Pterygopalatine/Infratemporal Fossa via the Transnasal Perpendicular Plate Palatine Bone or Transnasal Maxillary Sinus Approach.

World Neurosurg 2018 Dec 13;120:e1011-e1016. Epub 2018 Sep 13.

Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair, Chinese Medical Association Neuroendoscopic Training Base and Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong, Jiangsu Province, China. Electronic address:

Background: Both the pterygopalatine fossa (PPF) and the infratemporal fossa (ITF) lie outside the midline of the skull base. Lesions in the PPF or ITF include trigeminal schwannoma (trigeminal schwannoma, TS), which originates from the second or third branch of the trigeminal nerve (maxillary nerve or mandibular nerve). Due to their typically deep anatomic location, lesions in the PPF or ITF can be difficult to treat using traditional surgical approaches. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.08.216DOI Listing
December 2018
4 Reads

Contralateral Botulinum Toxin Improved Functional Recovery after Tibial Nerve Repair in Rats.

Plast Reconstr Surg 2018 12;142(6):1511-1519

São Paulo, Brazil From the Plastic Surgery Division and the Department of Otorhinolaryngology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo.

Background: There is clinical and experimental evidence that botulinum toxin applied to the healthy side of patients with facial paralysis positively affects functional recovery of the paralyzed side. The authors created an experimental model to study the effects of botulinum toxin injection in the gastrocnemius muscle contralateral to the side of tibial nerve lesion/repair in rats.

Methods: Fifty rats were allocated into five groups: group I, control; group II, tibial nerve section; group III, tibial nerve section and immediate neurorrhaphy; group IV, tibial nerve section, immediate neurorrhaphy, and botulinum toxin injected into the contralateral gastrocnemius muscle; and group V, botulinum toxin injected into the gastrocnemius muscle and no surgery. Read More

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http://dx.doi.org/10.1097/PRS.0000000000004981DOI Listing
December 2018
13 Reads

Effects of the Number of Muscle-Nerve-Muscle Grafts on Rat Facial Nerve Functional Recovery.

Ann Otol Rhinol Laryngol 2018 Nov 5;127(11):791-797. Epub 2018 Sep 5.

1 Department of Otolaryngology-Head and Neck Surgery, Loyola University of Chicago, Maywood, IL, USA.

Introduction: Facial nerve denervation can be devastating for patients. Primary neurorrhaphy and interposition (IP) nerve grafting are common reinnervation techniques. Muscle-nerve-muscle (MNM) grafting is a lesser known alternative. Read More

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http://dx.doi.org/10.1177/0003489418795980DOI Listing
November 2018
1 Read

Using Three-Dimensional Printing to Create Individualized Cranial Nerve Models for Skull Base Tumor Surgery.

World Neurosurg 2018 Dec 16;120:e142-e152. Epub 2018 Aug 16.

Biomanufacturing Center, Department of Mechanical Engineering, Tsinghua University, Beijing, China. Electronic address:

Objective: Using three-dimensional (3D) printing to create individualized patient models of the skull base, the optic chiasm and facial nerve can be previsualized to help identify and protect these structures during tumor removal surgery.

Methods: Preoperative imaging data for 2 cases of sellar tumor and 1 case of acoustic neuroma were obtained. Based on these data, the cranial nerves were visualized using 3D T1-weighted turbo field echo sequence and diffusion tensor imaging-based fiber tracking. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.236DOI Listing
December 2018
23 Reads

Adipose-derived stem cells and the stromal vascular fraction in polyglycolic acid-collagen nerve conduits promote rat facial nerve regeneration.

Wound Repair Regen 2018 11 25;26(6):446-455. Epub 2018 Oct 25.

Department of Plastic and Reconstructive Surgery, Tokyo Women's Medical University, Tokyo, Japan.

Adipose-derived stem cells (ADSCs) and the stromal vascular fraction (SVF) promote nerve regeneration. Biodegradable nerve conduits are used to treat peripheral nerve injuries, but their efficiencies are lower than those of autologous nerve grafts. This study developed biodegradable nerve conduits containing ADSCs and SVF and evaluated their facial nerve regenerating abilities in a rat model with a 7-mm nerve defect. Read More

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http://dx.doi.org/10.1111/wrr.12665DOI Listing
November 2018
32 Reads

Application of Delayed Surgical Managements in Patients with Stensen's Duct Injury.

Curr Med Sci 2018 Jun 22;38(3):519-523. Epub 2018 Jun 22.

Center of Stomatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

The study aimed to retrospectively evaluate surgical treatment outcomes after delayed parotid gland and duct injuries. Nine patients subjected to parotid gland and duct injuries with 1- to 3-month treatment delay were retrospectively evaluated with special reference of etiology, past medical history, and injury location. Conservative treatment, microsurgical anastomosis, and diversion of salivary flow or ligation were chosen for delayed parotid gland and duct injuries concerning to their site of injury, time of repair and procedures. Read More

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http://dx.doi.org/10.1007/s11596-018-1909-yDOI Listing
June 2018
12 Reads

An Experimental Study on the Optimal Timing for the Repair of Incomplete Facial Paralysis by Hypoglossal-facial 'Side'-to-side Neurorrhaphy in Rats.

Biomed Environ Sci 2018 Jun;31(6):413-424

Beijing Neurosurgical Institute, Capital Medical University, Beijing 100050, China.

Objective: To investigate the optimal timing for the repair of persistent incomplete facial paralysis by hypoglossal-facial 'side'-to-side neurorrhaphy in rats.

Methods: A total of 30 adult rats with crushed and bulldog-clamped facial nerve injury were randomly divided into 5 groups (n = 6 each) that were subjected to injury without nerve repair or with immediate repair, 2-week-delayed repair, 4-week-delayed repair, or 8-week-delayed repair. Three months later, the effects of repair in each rat were evaluated by facial symmetry assessment, electrophysiological examination, retrograde labeling, and axon regeneration measurement. Read More

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http://dx.doi.org/10.3967/bes2018.055DOI Listing
June 2018
13 Reads
1.650 Impact Factor

Preliminary outcomes of endoscopic middle-ear surgery in 103 cases: a UK experience.

J Laryngol Otol 2018 Jun;132(6):493-496

Department of Otolaryngology,University Hospital Monklands, NHS Lanarkshire,Airdrie,Scotland,UK.

Background: Totally endoscopic ear surgery and endoscope-assisted microsurgery are still new concepts, with relatively few centres in the UK performing them. Advantages include better visualisation of difficult to reach areas, such as the sinus tympani, and limited external incisions. This paper reports our short-term outcomes for endoscopic middle-ear surgery. Read More

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http://dx.doi.org/10.1017/S0022215118000695DOI Listing
June 2018
3 Reads

Anterior Greater Auricular Point: Novel Anatomic Landmark to Facilitate Harvesting of the Greater Auricular Nerve.

World Neurosurg 2018 Nov 11;119:e64-e70. Epub 2018 Jul 11.

Department of Neurosurgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA. Electronic address:

Background: The greater auricular nerve (GAN) may be used as a nerve graft during neurosurgical procedures to repair damaged nerves. There is extensive literature on localization of the GAN at the posterior triangle of the neck, but objective information on localization of the GAN at the anterior triangle of the neck close to cranial neurosurgical fields is lacking. The aim of this study was to introduce simple and reliable landmarks to localize the GAN at the anterior triangle of the neck to facilitate its harvest during neurosurgical procedures. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.07.001DOI Listing
November 2018
11 Reads

Comprehensive approach to reestablishing form and function after radical parotidectomy.

Am J Otolaryngol 2018 Sep - Oct;39(5):542-547. Epub 2018 Jun 7.

Cleveland Clinic Foundation, 9500 Euclid Ave, Cleveland, OH 44195, USA.

Introduction: The reconstructive goals following radical parotidectomy include restoration of symmetry, reanimation of the face, and reestablishment of oral competence. We present our experience utilizing the anterolateral thigh (ALT) free flap, orthodromic temporalis tendon transfer (OTTT), and facial nerve cable grafting to reestablish form and function.

Material And Methods: From 2010 to 2016, 17 patients underwent radical parotidectomy followed by immediate reconstruction. Read More

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http://dx.doi.org/10.1016/j.amjoto.2018.06.008DOI Listing
December 2018
11 Reads

[Research of acellular xenogeneic nerve combined with adipose-derived stem cells and platelet rich plasma in repair of rabbit facial nerve injury].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 Jun;32(6):736-744

Department of Burn Plastic Surgery, the First Affiliated Hospital of Jinzhou Medical University, Jinzhou Liaoning, 121000, P.R.China.

Objective: To investigate the early effects of acellular xenogeneic nerve combined with adipose-derived stem cells (ADSCs) and platelet rich plasma (PRP) in repairing facial nerve injury in rabbits.

Methods: The bilateral sciatic nerves of 15 3-month-old male Sprague-Dawley rats were harvested and decellularized as xenografts. The allogeneic ADSCs were extracted from the neck and back fat pad of healthy adult New Zealand rabbits with a method of digestion by collagenase type Ⅰ and the autologous PRP was prepared by two step centrifugation. Read More

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http://dx.doi.org/10.7507/1002-1892.201711079DOI Listing
June 2018
5 Reads

Middle Cranial Fossa Approach to Repair Tegmen Defects with Autologous or Alloplastic Graft.

World Neurosurg 2018 Oct 2;118:e10-e17. Epub 2018 Jun 2.

Division of Neurological Surgery, University of Missouri School of Medicine, Columbia, Missouri, USA. Electronic address:

Background: Temporal bone tegmen defects may be associated with cerebrospinal fluid (CSF) otorrhea. A variety of techniques have been used for repair. We report our experience with skull base reconstruction for tegmen defects using either autologous or alloplastic grafts. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.05.196DOI Listing
October 2018
21 Reads

Comparison of osseous healing after sagittal split ramus osteotomy and intraoral vertical ramus osteotomy.

Int J Oral Maxillofac Surg 2018 Oct 26;47(10):1316-1321. Epub 2018 May 26.

Department of Clinical Oral Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, Nagasaki, Japan.

The sagittal split ramus osteotomy (SSRO) is generally associated with greater postoperative stability than the intraoral vertical ramus osteotomy (IVRO); however, it entails a risk of inferior alveolar nerve damage. In contrast, IVRO has the disadvantages of slow postoperative osseous healing and projection of the antegonial notch, but inferior alveolar nerve damage is believed to be less likely. The purposes of this study were to compare the osseous healing processes associated with SSRO and IVRO and to investigate changes in mandibular width after IVRO in 29 patients undergoing mandibular setback. Read More

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http://dx.doi.org/10.1016/j.ijom.2018.05.013DOI Listing
October 2018
2 Reads

Functional and Anatomical Outcomes of Facial Nerve Injury With Application of Polyethylene Glycol in a Rat Model.

JAMA Facial Plast Surg 2018 May 17. Epub 2018 May 17.

Department of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis.

Importance: Functional and anatomical outcomes after surgical repair of facial nerve injury may be improved with the addition of polyethylene glycol (PEG) to direct suture neurorrhaphy. The application of PEG has shown promise in treating spinal nerve injuries, but its efficacy has not been evaluated in treatment of cranial nerve injuries.

Objective: To determine whether PEG in addition to neurorrhaphy can improve functional outcomes and synkinesis after facial nerve injury. Read More

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http://dx.doi.org/10.1001/jamafacial.2018.0308DOI Listing
May 2018
3 Reads

[Effect of facial artery musculo-mucosal flap in reconstructing defects of tongue and mouth floor].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 Apr;31(4):461-464

Departmentof Oral and Maxillofacial Surgery, the Affiliated Hospital of Guilin Medical College, Guilin Guangxi, 541001, P.R.China.

Objective: To explore the effect of facial artery musculo-mucosal (FAMM) flap to reconstruct tongue and floor of mouth defects.

Methods: Between January 2011 and January 2016, 24 cases of tongue and floor of mouth defects were repaired with FAMM flap after tumor resection. There were 16 males and 8 females, aged from 38 to 70 years with an average of 55 years. Read More

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http://www.rrsurg.com/article/10.7507/1002-1892.201611108
Publisher Site
http://dx.doi.org/10.7507/1002-1892.201611108DOI Listing
April 2017
21 Reads

[Experimental study of using chitosan nerve conduit combined with PRP to repair facial nerve defect].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Oct;31(19):1496-1500;1503

Department of Oral and Maxillofacial Surgery,Zhongshan Hospital Affiliated to Dalian University,Dalian,116001,China.

The purpose of this study was to produce chitosan nerve conduit in order to investigate the feasibility of chitosan nerve conduit combined with autologous platelet-rich plasma (PRP) for repairing facial nerve defects.Forty New Zealand white rabbits were randomly divided into four groups (n=10 in each group).Establishment of the facial nerve defect model of the upper buccal branches was placed in the nerve regeneration catheter and injected with the same amount of PRP and saline. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2017.19.008DOI Listing
October 2017

End-to-end and end-to-side neurorrhaphy between thick donor nerves and thin recipient nerves: an axon regeneration study in a rat model.

Neural Regen Res 2018 Apr;13(4):699-703

Department of Plastic and Reconstructive Surgery, St. Marianna Medical University, Kawasaki City, Japan.

During nerve reconstruction, nerves of different thicknesses are often sutured together using end-to-side neurorrhaphy and end-to-end neurorrhaphy techniques. In this study, the effect of the type of neurorrhaphy on the number and diameter of regenerated axon fibers was studied in a rat facial nerve repair model. An inflow-type end-to-side and end-to-end neurorrhaphy model with nerve stumps of different thicknesses (2:1 diameter ratio) was created in the facial nerve of 14 adult male Sprague-Dawley rats. Read More

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http://dx.doi.org/10.4103/1673-5374.230296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950681PMC
April 2018
11 Reads

Electrophysiological assessment of a peptide amphiphile nanofiber nerve graft for facial nerve repair.

J Tissue Eng Regen Med 2018 Jun 16;12(6):1389-1401. Epub 2018 May 16.

Department of Otolaryngology-Head and Neck Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.

Facial nerve injury can cause severe long-term physical and psychological morbidity. There are limited repair options for an acutely transected facial nerve not amenable to primary neurorrhaphy. We hypothesize that a peptide amphiphile nanofiber neurograft may provide the nanostructure necessary to guide organized neural regeneration. Read More

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http://dx.doi.org/10.1002/term.2669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269104PMC
June 2018
7 Reads

3D bio-printed scaffold-free nerve constructs with human gingiva-derived mesenchymal stem cells promote rat facial nerve regeneration.

Sci Rep 2018 Apr 26;8(1):6634. Epub 2018 Apr 26.

Department of Oral and Maxillofacial Surgery and Pharmacology, University of Pennsylvania School of Dental Medicine, 240 South 40th Street, Philadelphia, PA19104, USA.

Despite the promising neuro-regenerative capacities of stem cells, there is currently no licensed stem cell-based product in the repair and regeneration of peripheral nerve injuries. Here, we explored the potential use of human gingiva-derived mesenchymal stem cells (GMSCs) as the only cellular component in 3D bio-printed scaffold-free neural constructs that were transplantable to bridge facial nerve defects in rats. We showed that GMSCs have the propensity to aggregate into compact 3D-spheroids that could produce their own matrix. Read More

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http://www.nature.com/articles/s41598-018-24888-w
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http://dx.doi.org/10.1038/s41598-018-24888-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5919929PMC
April 2018
9 Reads

An anterolateral thigh chimeric flap for dynamic facial and esthetic reconstruction after oncological surgery in the maxillofacial region: a case report.

Head Face Med 2018 Apr 11;14(1). Epub 2018 Apr 11.

Department of Oral and Maxillofacial Surgery, University of Szeged, Kálvária 57, Szeged, H-6725, Hungary.

Background: The surgical management of malignant tumors in the head and neck region often leads to functional and esthetic defects that impair the quality of life of the patients. Reconstruction can be solved with prostheses in these cases, but various types of microsurgical free flaps can provide a better clinical outcome.

Case Presentation: In this case report, the tumor and parts of the involved facial muscles and nerve were excised surgically from a 42-year-old patient after a third relapse of basal cell carcinoma in the left midface. Read More

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http://dx.doi.org/10.1186/s13005-018-0164-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896052PMC
April 2018
1 Read

Outcomes From Lateral Eyelid Coupling for Facial Paralysis Using the Modified Tarsoconjunctival Flap.

JAMA Facial Plast Surg 2018 Sep;20(5):381-386

Department of Otolaryngology-Head and Neck Surgery, University of California, Davis, Sacramento.

Importance: In the setting of facial paralysis, inadequate eyelid closure and lower eyelid ectropion can lead to corneal exposure and impaired quality of life. Repair of paralytic ectropion is challenging, and an ideal surgical approach for all cases has not been identified.

Objective: To assess the patient-reported outcomes and eyelid position improvement in patients with flaccid facial paralysis undergoing lateral eyelid coupling with a tarsal strip canthoplasty and modified tarsoconjunctival flap to correct eyelid malposition. Read More

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http://dx.doi.org/10.1001/jamafacial.2018.0070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233623PMC
September 2018
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Clinical Application of Foci Contralateral Facial Artery Myomucosal Flap for Tongue Defect Repair.

Plast Reconstr Surg Glob Open 2018 Feb 26;6(2):e1669. Epub 2018 Feb 26.

Department of Stomatology, Affiliated Hospital of Guilin Medical College, Guilin, China.

This study aims to investigate the clinical efficacy of foci contralateral facial artery myomucosal flap (FAMF) in repairing the defect of tongue after tumor resection. There were 10 cases who received the operation to repair tongue tissue defects caused by tumor resection from January 2010 to January 2016. FAMF flap size ranged from 2. Read More

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http://dx.doi.org/10.1097/GOX.0000000000001669DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865938PMC
February 2018
6 Reads

Dynamic Quantitative Assessment of Motor Axon Sprouting after Direct Facial-Hypoglossal End-To-Side Neurorrhaphy in Rats.

J Reconstr Microsurg 2018 Jul 1;34(6):436-445. Epub 2018 Apr 1.

Department of Neurosurgery, XinHua Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.

Background:  End-to-side (ETS) neurorrhaphy is a promising procedure for peripheral nerve repair, yet controversies regarding the efficacy of this repair in facial nerve anastomosis for facial paralysis still exist.

Materials And Methods:  Thirty rats were divided into three groups: intact control group, direct facial-hypoglossal ETS neurorrhaphy, and end-to-end (ETE) neurorrhaphy. Nerve regeneration was assessed with vibrissae motor performance, electrophysiological tests, retrograde labeling, and histomorphological analysis at 4 and 8 months postoperatively. Read More

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http://dx.doi.org/10.1055/s-0038-1636539DOI Listing
July 2018
11 Reads

Incidence, Risk Factors, and Management of Blindness after Orbital Surgery.

Ophthalmology 2018 Jul 15;125(7):1100-1108. Epub 2018 Mar 15.

Department of Ophthalmology, University of Washington, Seattle, Washington.

Purpose: Severe vision loss is a risk of orbital surgery which physicians should counsel patients about, but the overall risk rate is unknown. This research was conducted to determine the risk of severe vision loss related to orbital surgery.

Design: Retrospective review. Read More

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http://dx.doi.org/10.1016/j.ophtha.2018.01.030DOI Listing
July 2018
3 Reads

Valproic Acid Promotes Survival of Facial Motor Neurons in Adult Rats After Facial Nerve Transection: a Pilot Study.

J Mol Neurosci 2018 Apr 12;64(4):512-522. Epub 2018 Mar 12.

Department of Otolaryngology-Head and Neck Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, China.

Valproic acid (VPA), a medication primarily used to treat epilepsy and bipolar disorder, has been applied to the repair of central and peripheral nervous system injury. The present study investigated the effect of VPA on functional recovery, survival of facial motor neurons (FMNs), and expression of proteins in rats after facial nerve trunk transection by functional measurement, Nissl staining, TUNEL, immunofluorescence, and Western blot. Following facial nerve injury, all rats in group VPA showed a better functional recovery, which was significant at the given time, compared with group NS. Read More

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http://dx.doi.org/10.1007/s12031-018-1051-0DOI Listing
April 2018
7 Reads

Experiences with a modified preauricular mini incision with subdermally dissection in condylar and subcondylar fractures of the mandible.

J Craniomaxillofac Surg 2018 Apr 8;46(4):588-593. Epub 2018 Feb 8.

Regional Training and Research Hospital, Plastic and Reconstructive Surgery Clinic, Erzurum, Turkey.

Objective: Condylar and subcondylar fractures (CSFs) are among the most common mandible fractures. If reduction of these fractures is not carried out correctly, serious complications can result, including infection, damage to temporomandibular joint (TMJ) function, malocclusion, nonunion, malunion, and ankylosis of the TMJ.

Methods: We used a preauricular, mini-incision, open technique (PMIOT) for CSF of the mandible. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.01.018DOI Listing
April 2018
10 Reads

Anomalous Extratemporal Facial Nerve in Oculoauriculovertebral Spectrum.

Cleft Palate Craniofac J 2018 May 28;55(5):769-772. Epub 2018 Feb 28.

1 Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Ottawa, Ontario, Canada.

Facial nerve dysfunction is common in oculoauriculovertebral spectrum (OAVS). However, the course of the nerve has rarely been described. A 23-year-old woman with OAVS underwent excision of microtic ear remnants in preparation for an osseointegrated prosthesis and suffered iatrogenic transection of the facial nerve-the pes anserinus was within the subcutaneous tissue 15 mm posterior and 15 mm cephalad to the external acoustic meatus. Read More

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http://dx.doi.org/10.1177/1055665618756707DOI Listing
May 2018
1 Read

Surgical Treatment for Extracapsular Condylar Fractures of the Mandible.

J Craniofac Surg 2018 Jul;29(5):1312-1315

Cajuru Universitary Hospital, Curitiba, Brazil.

Background: Condylar fractures are considered the most controversial mandibular fractures, regarding both the diagnosis and the treatment. With the increase in surgical indications for handling this type of fracture, it is important to discuss about the advantages and disadvantages of the several surgical approaches available. This article describes the surgical details and postoperative results of the mini-retromandibular transparotid approach for treating extracapsular condylar fractures of the mandible. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004344DOI Listing
July 2018
7 Reads

Total Lower Lip Reconstruction With Functional Gracilis Free Muscle Flap.

J Craniofac Surg 2018 May;29(3):735-737

Department of Plastic Reconstructive and Aesthetic Surgery.

Free flaps based on static slings principles cannot provide esthetic and functional outcomes at a desired level in total or close to total lip loss. Therefore, dynamic methods have become a current issue in recent years and especially the idea of functional gracilis free muscle flap has been suggested. In this study, we present a case of a successful total lower lip repair with this flap. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004331DOI Listing
May 2018
7 Reads