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Stroke risk and outcomes in epilepsy patients: Two retrospective cohort studies based on National Health Insurance in Taiwan.

Atherosclerosis 2018 Nov 23;280:147-154. Epub 2018 Nov 23.

Department of Anesthesiology, Shuan Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan; Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:

Background And Aims: The risk of stroke in epileptic patients and the impact of epilepsy history on stroke patients' outcome have not been studied completely. Our purpose is to evaluate whether patients with epilepsy have increased risk of stroke or post-stroke mortality.

Methods: In Study I, we conducted a retrospective cohort study of 6746 patients with newly diagnosed epilepsy and 26,984 persons without epilepsy between 2000 and 2008, in the database of National Health Insurance in Taiwan. Read More

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November 2018

Visual stimulus-driven functional organization of macaque prefrontal cortex.

Neuroimage 2018 Dec 3. Epub 2018 Dec 3.

Laboratory of Sensorimotor Research, National Eye Institute, National Institute of Mental Health, National Institutes of Health, 20892, Bethesda, United States. Electronic address:

The extent to which the major subdivisions of prefrontal cortex (PFC) can be functionally partitioned is unclear. In approaching the question, it is often assumed that the organization is task dependent. Here we use fMRI to show that PFC can respond in a task-independent way, and we leverage these responses to uncover a stimulus-driven functional organization. Read More

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December 2018
3 Reads

Daily energy expenditure of males following alternative reproductive tactics: Solitary roamers spend more energy than group-living males.

Physiol Behav 2018 Dec 3. Epub 2018 Dec 3.

School of Animal, Plant & Environmental Sciences, University of the Witwatersrand, Private Bag 3, WITS, 2050 Johannesburg, South Africa; IPHC, UNISTRA, CNRS, 23 rue du Loess, 67200 Strasbourg, France.

In many species, males follow alternative reproductive tactics (ARTs), where one tactic (called bourgeois) has much higher reproductive success than alternative tactics followed by males with lower competitive ability. The extent to which ARTs differ in energetic costs is unknown, but it is important to understand the fitness payoffs of ARTs. We studied male African striped mice (Rhabdomys pumilio) which follow one of three ARTs: heavy bourgeois males defend harems of females and have 10 times higher reproductive success than smaller roamers, which have ten times higher reproductive success than philopatric males, which remain in their natal group and are the smallest males. Read More

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December 2018

Computer-assisted diagnosis techniques (dermoscopy and spectroscopy-based) for diagnosing skin cancer in adults.

Cochrane Database Syst Rev 2018 Dec 3;12:CD013186. Epub 2018 Dec 3.

Institute of Applied Health Research, University of Birmingham, Edgbaston Campus, Birmingham, UK, B15 2TT.

Background: Early accurate detection of all skin cancer types is essential to guide appropriate management and to improve morbidity and survival. Melanoma and cutaneous squamous cell carcinoma (cSCC) are high-risk skin cancers which have the potential to metastasise and ultimately lead to death, whereas basal cell carcinoma (BCC) is usually localised with potential to infiltrate and damage surrounding tissue. Anxiety around missing early curable cases needs to be balanced against inappropriate referral and unnecessary excision of benign lesions. Read More

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December 2018
4 Reads

Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults.

Cochrane Database Syst Rev 2018 Dec 3;12:CD011901. Epub 2018 Dec 3.

Institute of Applied Health Research, University of Birmingham, Birmingham, UK, B15 2TT.

Background: Early accurate detection of all skin cancer types is important to guide appropriate management, to reduce morbidity and to improve survival. Basal cell carcinoma (BCC) is almost always a localised skin cancer with potential to infiltrate and damage surrounding tissue, whereas a minority of cutaneous squamous cell carcinomas (cSCCs) and invasive melanomas are higher-risk skin cancers with the potential to metastasise and cause death. Dermoscopy has become an important tool to assist specialist clinicians in the diagnosis of melanoma, and is increasingly used in primary-care settings. Read More

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December 2018
2 Reads

Teledermatology for diagnosing skin cancer in adults.

Cochrane Database Syst Rev 2018 Dec 3;12:CD013193. Epub 2018 Dec 3.

Institute of Applied Health Research, University of Birmingham, Birmingham, UK, B15 2TT.

Background: Early accurate detection of all skin cancer types is essential to guide appropriate management and to improve morbidity and survival. Melanoma and squamous cell carcinoma (SCC) are high-risk skin cancers which have the potential to metastasise and ultimately lead to death, whereas basal cell carcinoma (BCC) is usually localised with potential to infiltrate and damage surrounding tissue. Anxiety around missing early curable cases needs to be balanced against inappropriate referral and unnecessary excision of benign lesions. Read More

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December 2018
5 Reads

Visual inspection for diagnosing cutaneous melanoma in adults.

Cochrane Database Syst Rev 2018 Dec 3;12:CD013194. Epub 2018 Dec 3.

Institute of Applied Health Research, University of Birmingham, Birmingham, UK, B15 2TT.

Background: Melanoma has one of the fastest rising incidence rates of any cancer. It accounts for a small percentage of skin cancer cases but is responsible for the majority of skin cancer deaths. History-taking and visual inspection of a suspicious lesion by a clinician is usually the first in a series of 'tests' to diagnose skin cancer. Read More

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December 2018
3 Reads

Dermoscopy, with and without visual inspection, for diagnosing melanoma in adults.

Cochrane Database Syst Rev 2018 Dec 3;12:CD011902. Epub 2018 Dec 3.

Institute of Applied Health Research, University of Birmingham, Birmingham, UK, B15 2TT.

Background: Melanoma has one of the fastest rising incidence rates of any cancer. It accounts for a small percentage of skin cancer cases but is responsible for the majority of skin cancer deaths. Although history-taking and visual inspection of a suspicious lesion by a clinician are usually the first in a series of 'tests' to diagnose skin cancer, dermoscopy has become an important tool to assist diagnosis by specialist clinicians and is increasingly used in primary care settings. Read More

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December 2018
4 Reads

Application of the Andersen-Newman model of health care utilization to understand antenatal care use in Kersa District, Eastern Ethiopia.

PLoS One 2018 6;13(12):e0208729. Epub 2018 Dec 6.

Research Centre for Generational Health and Ageing, Faculty of Health and Medicine, University of Newcastle, Newcastle, NSW, Australia.

Background: In Ethiopia, the uptake of antenatal care services has been low. Moreover, there is less frequent and late attendance of antenatal care among women who attend. Using the Anderson-Newman model of health care utilization, this study identified factors that either facilitate or impede antenatal care utilization in Kersa district, Eastern Ethiopia. Read More

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December 2018
1 Read

Climatic factors shaping intraspecific leaf trait variation of a neotropical tree along a rainfall gradient.

PLoS One 2018 6;13(12):e0208512. Epub 2018 Dec 6.

Departamento de Botânica, Universidade Federal de Minas Gerais, ICB-UFMG, Belo Horizonte, Brazil.

Intraspecific trait variation has been singled out as an important mechanism by which individuals can cope with environmental variations and avoid local extinctions. Here we evaluate variation in metamer traits (i.e. Read More

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December 2018

The eyes know it: Toddlers' visual scanning of sad faces is predicted by their theory of mind skills.

PLoS One 2018 6;13(12):e0208524. Epub 2018 Dec 6.

Department of Psychology, Concordia University, Montréal, Québec, Canada.

The current research explored toddlers' gaze fixation during a scene showing a person expressing sadness after a ball is stolen from her. The relation between the duration of gaze fixation on different parts of the person's sad face (e.g. Read More

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December 2018
4 Reads

Inflammatory and Infectious Syndromes Associated with Cancer Immunotherapies.

Clin Infect Dis 2018 Dec 6. Epub 2018 Dec 6.

Department of Medicine, Harvard Medical School, Boston, MA, USA.

Immunotherapy using antibodies to immune checkpoint molecules or targeted chimeric antigen receptor-modified T (CAR-T) cells represent dramatic advances in cancer treatment. These therapies mediate immune-related adverse events (irAEs) which may mimic or amplify infectious presentations. Checkpoint inhibitor therapy may be associated with diverse irAEs including mild skin, endocrine and autoimmune manifestations or severe inflammatory processes including colitis, pneumonitis, myocarditis, and shock. Read More

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December 2018
2 Reads

Cervical Discs as a Source of Neck Pain. An Analysis of the Evidence.

Pain Med 2018 Dec 6. Epub 2018 Dec 6.

Faculty of Medicine and Health Sciences, The University of Newcastle, Newcastle, Australia.

Objectives.: To determine the extent and strength of evidence that supports the belief that cervical intervertebral discs are a source of neck pain. The evidence from anatomical, laboratory, experimental, diagnostic, and treatment studies was summarized and analyzed for concept validity, face validity, content validity, and construct validity. Read More

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December 2018
1 Read

Involving people with dementia and their carers in dementia education for undergraduate healthcare professionals: a qualitative study of motivation to participate and experience.

Int Psychogeriatr 2018 Dec 6:1-8. Epub 2018 Dec 6.

Centre for Dementia Studies,Brighton and Sussex Medical School,Brighton,UK.

ABSTRACTBackground:There is a need to improve dementia education to prepare future generations of healthcare professionals to deal with the increasing challenges they will face. Time for Dementia is an innovative undergraduate education program for medical, nursing, and paramedic students in the south of England. Success of the program is dependent upon the participation of families (people with dementia and their carers). Read More

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December 2018

Improvements in the perception of facial attractiveness following surgical aesthetic treatment; study based on online before and after photos.

J Cosmet Dermatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Aesthetic Medicine, Medical University of Bialystok, Bialystok, Poland.

Background: Aesthetic surgery procedures such as lip augmentation, eyelid correction, face-lifting, or Botox treatment for lines and wrinkles are an important part of cosmetic surgery.

Objectives: The aim of the study was to estimate improvement in appearance following plastic surgery using modern collective intelligence methods of validation.

Methods: A total of 108 photographs showing 54 patients prior to and following cosmetic surgery were downloaded from Internet web presentations of several unnamed plastic surgeons. Read More

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December 2018

The voice of patients in system redesign: A case study of redesigning a centralized system for intake of referrals from primary care to rheumatologists for patients with suspected rheumatoid arthritis.

Health Expect 2018 Dec 5. Epub 2018 Dec 5.

Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Background: The published literature demands examples of health-care systems designed with the active engagement of patients to explore the application of this complex phenomenon in practice.

Methods: This case study explored how the voice of patients was incorporated into the process of redesigning an element of the health-care system, a centralized system for intake of referrals from primary care to rheumatologists for patients with suspected rheumatoid arthritis (RA)-centralized intake. The phenomenon of patient engagement using "patient and community engagement researchers" (PaCERs) in research and the process of redesigning centralized intake were selected as the case. Read More

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December 2018

The effectiveness of topical therapy combined with 308-nm excimer laser on vitiligo compared to excimer laser monotherapy in pediatric patients.

Pediatr Dermatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.

We evaluated the efficiency of using a 308-nm excimer laser with either tacrolimus, pimecrolimus, or halometasone for the treatment of childhood vitiligo. Patients who received combined treatments had significantly higher rates of repigmentation in comparison with individuals who underwent excimer laser alone therapy. Moreover, patients who received treatment with excimer laser and halometasone had significantly higher rates of repigmentation, even higher than individuals who were treated with tacrolimus combined or pimecrolimus combined. Read More

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December 2018

Abortion by telemedicine in the European Union.

Int J Gynaecol Obstet 2018 Dec 5. Epub 2018 Dec 5.

Kent Law School, University of Kent, Canterbury, UK.

This paper analyses an important set of legal issues raised by the telemedical provision of abortion pills. Focusing on the case of European Union (EU) law, it suggests that a properly accredited doctor seeking to treat a patient with abortion pills is entitled, in principle, to rely on EU rules of free movement to protect their access to patients in other member states, and women facing unwanted pregnancies likewise have legal rights to access the services thus offered. EU countries seeking to claim an exception to those rules on the basis of public health or the protection of a fundamental public policy interest (here, the protection of fetal life) will face significant barriers. Read More

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December 2018
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Efficacy of external cold and a vibrating device in reducing discomfort of dental injections in children: A split mouth randomised crossover study.

Eur Arch Paediatr Dent 2018 Dec 5. Epub 2018 Dec 5.

Department of Paediatric Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Aim: To study the discomfort and fear associated with maxillary infiltration injections when using a combination of external cold and a commercially available vibrating device.

Methodology: A total of 60 children aged 7 years old participated in this split mouth randomised crossover study. The control intervention comprised of the administration of 1. Read More

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December 2018
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An original procedure for orbitonasal cutaneous infiltrative tumor repair, using combined forehead and melolabial propeller flaps.

Eur Arch Otorhinolaryngol 2018 Dec 5. Epub 2018 Dec 5.

Institut Universitaire de la Face et du Cou, Centre Hospitalier Universitaire de NICE, 31 Avenue de Valombrose, 06100, Nice, Alpes-Maritimes, France.

Introduction: Resections of cutaneous tumors in the medial orbitonasal region can be transfixing. Repairs using a single local flap run the risk of failure and that of secondary sinonasal fistula, especially in cases of surgery on a radiated field. We propose an original and reliable repair procedure using two pedicled regional flaps vascularized by two distinct arterial systems clinched together to reconstruct the mucosal and cutaneous planes. Read More

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December 2018

Exploration of a cultural-adaptation of the EQ-5D for Thai population: A "bolt-on" experiment.

Qual Life Res 2018 Dec 5. Epub 2018 Dec 5.

Division of Social and Administrative Pharmacy, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayuthaya Rd., Rajathevi, Bangkok, 10400, Thailand.

Purpose: As the EQ-5D was developed in western countries with only five dimensions, it might be insensitive to non-western populations including Thai. This study examined the impact of adding two candidate dimensions, "interpersonal relationships (IR)" and "activities related to bending knees (AK)," to the EQ-5D questionnaire, and evaluated their psychometric properties in a Thai population sample.

Methods: Face-to-face interviews were conducted with 600 Thai. Read More

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December 2018

Oxygen reserve index (ORi™) contributes to prediction of hypoxemia and patient safety during tracheal stent insertion using rigid bronchoscopy: a case report.

J Clin Monit Comput 2018 Dec 5. Epub 2018 Dec 5.

Department of Anesthesiology and Critical Care Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-Shi, Tochigi-Ken, 329-0498, Japan.

The oxygen reserve index (ORi™) is a new noninvasive and continuous variable, which represents a moderate hyperoxygenation status, with a unitless scale between 0.00 and 1.00. Read More

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December 2018

Is Awareness Enough to Bring Patients to Colorectal Screening?

Open Med (Wars) 2018 25;13:528-533. Epub 2018 Nov 25.

Department of Hygiene, University of Medicine and Pharmacy of Tirgu Mures, Tirgu Mures 540139, Romania.

Background: The aim of the study was to assess the awareness of colorectal cancer (CRC) patients about CRC screening methods and to investigate the relationship between awareness, socio-demographic characteristics and the stage in which patients with CRC are diagnosed.

Methods: The observational cross-sectional study included 275 CRC patients admitted between 2014 and 2016 to two surgical clinics from Tîrgu Mureş, Romania. Study variables were collected via face-to-face interview and from patients' observation sheets. Read More

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November 2018
3 Reads

Young key affected population in Myanmar: are there any challenges in seeking information and care for HIV/sexually transmitted infections and reproductive health?

F1000Res 2018 21;7:1515. Epub 2018 Sep 21.

Department of Medical Research, Ministry of Health and Sports, Yangon, 11191, Myanmar.

Unmet needs and barriers in seeking HIV/STI and RH information and care are present especially among young key affected population (YKAP). Therefore, the study was conducted to determine the health seeking behaviors of YKAP regarding HIV/STI and RH, and challenges in seeking health information and care. A cross-sectional, mixed-methods study was conducted at two large cities in Myanmar. Read More

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September 2018

Competition alters seasonal resource selection and promotes use of invasive shrubs by an imperiled native cottontail.

Ecol Evol 2018 Nov 25;8(22):11122-11133. Epub 2018 Oct 25.

Department of Environmental and Forest Biology SUNY College of Environmental Science and Forestry Syracuse New York.

Many ecosystems face multiple invaders, and interactions among invasive and native species may complicate conservation efforts for imperiled species. Examination of fine-scale resource selection can be used to detect patterns in habitat selection resulting from species interactions and assess the value of specific resources, including invasive plants, to wildlife. We used animal location data with mixed-effects resource selection models to examine seasonal competitive interactions and species-specific selection for forage and cover resources by an imperiled native lagomorph, the New England cottontail and its nonnative competitor, the eastern cottontail in the eastern Hudson Valley, NY. Read More

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November 2018

Measuring agreement among experts in classifying camera images of similar species.

Ecol Evol 2018 Nov 30;8(22):11009-11021. Epub 2018 Oct 30.

Department of Biology University of British Columbia Okanagan Kelowna British Columbia Canada.

Camera trapping and solicitation of wildlife images through citizen science have become common tools in ecological research. Such studies collect many wildlife images for which correct species classification is crucial; even low misclassification rates can result in erroneous estimation of the geographic range or habitat use of a species, potentially hindering conservation or management efforts. However, some species are difficult to tell apart, making species classification challenging-but the literature on classification agreement rates among experts remains sparse. Read More

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November 2018

Trade-off between reproductive and anti-competitor abilities in an insect-parasitic nematode-bacteria symbiosis.

Ecol Evol 2018 Nov 18;8(22):10847-10856. Epub 2018 Oct 18.

Department of Biology Indiana University Bloomington Indiana.

Mutualistic symbionts can provide diverse benefits to their hosts and often supply key trait variation for host adaptation. The bacterial symbionts of entomopathogenic nematodes play a crucial role in successful colonization of and reproduction in the insect host. Additionally, these symbionts can produce a diverse array of antimicrobial compounds to deter within-host competitors. Read More

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November 2018

Split-face Evaluation of a Multi-ingredient Brightening Foam Versus a Reference Control in Women with Photodamaged Facial Skin.

J Clin Aesthet Dermatol 2018 Oct 1;11(10):24-28. Epub 2018 Oct 1.

Drs. Stephens and Babcock are with Thomas J. Stephens and Associates, Inc. in Colorado Springs, Colorado.

The gold standard for the treatment of hyperpigmentation is hydroquinone (HQ), which has been available as a skin lightener for more than 50 years. Numerous clinical studies have proven its efficacy in various topical formulations. In the United States, HQ is available as a nonprescription product in 2% formulations and as a 4% prescription product. Read More

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October 2018
2 Reads

Exploring the Validity of the Perceived Restorativeness Soundscape Scale: A Psycholinguistic Approach.

Front Psychol 2018 16;9:2224. Epub 2018 Nov 16.

School of Information Studies and Centre for Interdisciplinary Research in Music Media and Technology, McGill University, Montreal, QC, Canada.

Soundscapes affect people's health and well-being and contribute to the perception of environments as restorative. This paper continues the validation process of a previously developed Perceived Restorativeness Soundscape Scale (PRSS). The study takes a novel methodological approach to explore the PRSS face and construct validity by examining the qualitative reasons for participants' numerical responses to the PRSS items. Read More

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November 2018

Involving "authentic" cancer patients, their caregivers, and multidisciplinary professionals in a quality improvement trajectory in a hospital cancer pathway: a study protocol.

J Multidiscip Healthc 2018 9;11:661-671. Epub 2018 Nov 9.

Department of Internal Medicine, Zuyderland Medical Centre, Sittard, The Netherlands,

Introduction: The implementation of oncology care pathways that standardize organizational procedures has improved cancer care in recent years. However, the involvement of "authentic" patients and caregivers in quality improvement of these predetermined pathways is in its infancy, especially the scholarly reflection on this process. We, therefore, aim to explore the multidisciplinary challenges both in practice, when cancer patients, their caregivers, and a multidisciplinary team of professionals work together on quality improvement, as well as in our research team, in which a social scientist, health care professionals, health care researchers, and experience experts design a research project together. Read More

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November 2018

Treatment of relapsed refractory multiple myeloma: which new PI-based combination treatments do patients prefer?

Patient Prefer Adherence 2018 9;12:2387-2396. Epub 2018 Nov 9.

Asklepios Kliniken Hamburg GmbH, 22763 Hamburg, Germany.

Background And Objectives: This study describes preferences of German relapsed refractory multiple myeloma (RRMM) patients with novel proteasome inhibitor-based combination treatments.

Methods: Patients with a minimum age of 18 years and a diagnosis of RRMM were included. Their preferences were assessed using a discrete choice experiment design, which was developed based on a literature review and two patient focus group discussions. Read More

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November 2018
1 Read

Quality of life following surgery for congenital glaucoma: findings of the LVPEI congenital glaucoma registry.

Eye (Lond) 2018 Dec 5. Epub 2018 Dec 5.

Jasti V Ramanamma Children's Eye Care Centre, L V Prasad Eye Institute, Hyderabad, India.

Purpose: To evaluate the health-related quality of life (HRQoL) of children operated for primary congenital glaucoma (PCG) using the Kidscreen-27 questionnaire.

Methods: A total of 121 children (mean age, 11.8 years; SD, 2. Read More

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December 2018

A proposed mechanism influencing structural patterns in X-linked retinoschisis and stellate nonhereditary idiopathic foveomacular retinoschisis.

Eye (Lond) 2018 Dec 5. Epub 2018 Dec 5.

Vitreous Retina Macula Consultants of New York, New York, NY, USA.

Objective: To explore the structural differences between X-linked retinoschisis (XLR) and stellate nonhereditary idiopathic foveomacular retinoschisis (SNIFR) using swept-source optical coherence tomography angiography (SS-OCTA).

Methods: A case series of two patients, a 9-year-old male with XLR and a 58-year-old woman with SNIFR were imaged with swept-source optical coherence tomography angiography (SS-OCTA; PLEX Elite 900, Carl Zeiss Meditec, Inc, Dublin, CA). Automated segmentation was manually adjusted to include the areas of retinoschisis within en face flow and structural slabs. Read More

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December 2018

A neutron tomography study: probing the spontaneous crystallization of randomly packed granular assemblies.

Sci Rep 2018 Dec 5;8(1):17637. Epub 2018 Dec 5.

Institut Laue-Langevin, 71 Avenue des Martyrs, 38000, Grenoble, France.

We study the spontaneous crystallization of an assembly of highly monodisperse steel spheres under shaking, as it evolves from localized icosahedral ordering towards a packing reaching crystalline ordering. Towards this end, real space neutron tomography measurements on the granular assembly are carried out, as it is systematically subjected to a variation of frequency and amplitude. As expected, we see a presence of localized icosahedral ordering in the disordered initial state (packing fraction ≈ 0. Read More

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December 2018

Tuning structure and mechanical properties of Ta-C coatings by N-alloying and vacancy population.

Sci Rep 2018 Dec 5;8(1):17669. Epub 2018 Dec 5.

Institute of Materials Science and Technology, TU Wien, A-1060, Wien, Austria.

Tailoring mechanical properties of transition metal carbides by substituting carbon with nitrogen atoms is a highly interesting approach, as thereby the bonding state changes towards a more metallic like character and thus ductility can be increased. Based on ab initio calculations we could prove experimentally, that up to a nitrogen content of about 68% on the non-metallic sublattice, Ta-C-N crystals prevail a face centered cubic structure for sputter deposited thin films. The cubic structure is partly stabilized by non-metallic as well as Ta vacancies - the latter are decisive for nitrogen rich compositions. Read More

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December 2018
2 Reads

Cardiac parasympathetic activity and ventricular diastolic interactions in individuals with spinal cord injury.

Spinal Cord 2018 Dec 5. Epub 2018 Dec 5.

Department of Kinesiology, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, L2S 3A1, ON, Canada.

Study Design: Cohort cross-sectional study.

Objective: To investigate the relationship between cardiac vagal activity and left ventricular filling at rest and during vagal stimulation, via the cold face test (CFT), in individuals with spinal cord injury (SCI).

Setting: University-based laboratory at Brock University, St. Read More

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December 2018

Marine probiotics: increasing coral resistance to bleaching through microbiome manipulation.

ISME J 2018 Dec 5. Epub 2018 Dec 5.

Institute of Microbiology, Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, Brazil.

Although the early coral reef-bleaching warning system (NOAA/USA) is established, there is no feasible treatment that can minimize temperature bleaching and/or disease impacts on corals in the field. Here, we present the first attempts to extrapolate the widespread and well-established use of bacterial consortia to protect or improve health in other organisms (e.g. Read More

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December 2018

How Inclusive, User-Centered Design Research Can Improve Psychological Therapies for Psychosis: Development of SlowMo.

JMIR Ment Health 2018 Dec 5;5(4):e11222. Epub 2018 Dec 5.

Department of Psychology, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Background: Real-world implementation of psychological interventions for psychosis is poor. Barriers include therapy being insufficiently usable and useful for a diverse range of people. User-centered, inclusive design approaches could improve the usability of therapy, which may increase uptake, adherence, and effectiveness. Read More

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December 2018

Clinical Use of a Home Sleep Apnea Test: An Updated American Academy of Sleep Medicine Position Statement.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Abstract: The diagnosis and effective treatment of obstructive sleep apnea (OSA) in adults is an urgent health priority. It is the position of the American Academy of Sleep Medicine (AASM) that only a medical provider can diagnose medical conditions such as OSA and primary snoring. Throughout this statement, the term "medical provider" refers to a licensed physician and any other health care professional who is licensed to practice medicine in accordance with state licensing laws and regulations. Read More

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November 2018

Practical Implementation of a Single-Night Split-Titration Protocol With BPAP-ST and AVAPS in Patients With Neuromuscular Disease.

J Clin Sleep Med 2018 Nov 29. Epub 2018 Nov 29.

Study Objectives: At the sleep laboratory, noninvasive positive pressure ventilation titration protocols in patients with neuromuscular disease (NMD) are based on standard pressure cycle devices in a spontaneous/timed mode (BPAP-ST). Experience integrating protocols on average volume-assured pressure support (AVAPS) mode is limited, prompting us to develop a practical single-night titration protocol that provides information to assist clinicians and patients as they decide between BPAP-ST and AVAPS modes.

Methods: We implemented a sequential titration protocol of BPAP-ST followed by AVAPS during a single-night polysomnography study in patients with NMD and reported polysomnographic and clinical metrics. Read More

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November 2018

Increased risk of chronic fatigue syndrome following burn injuries.

J Transl Med 2018 Dec 5;16(1):342. Epub 2018 Dec 5.

Department of Health Policy and Management, Johns Hopkins University Bloomberg School of Public Health, Baltimore, United States.

Background: The overlapping symptoms and pathophysiological similarities between burn injury and chronic fatigue syndrome (CFS) are noteworthy. Thus, this study explores the possible association between burn injury and the subsequent risk of CFS.

Method: We used data from the Taiwan National Health Insurance system to address the research topic. Read More

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December 2018

Accrediting private providers with National Health Insurance to better serve low-income populations in Kenya and Ghana: a qualitative study.

Authors:
Lauren Suchman

Int J Equity Health 2018 Dec 5;17(1):179. Epub 2018 Dec 5.

Institute for Global Health Sciences, University of California San Francisco, San Francisco, California, USA.

Background: Small private providers in low- and middle-income countries (LMICs) are well positioned to fill gaps in services to low-income populations using Social Health Insurance (SHI) schemes. However, we know little about the practical challenges both private providers and patients face in the context of SHI that may ultimately limit access to quality services for low-income populations. In this paper, we pull together data collected from private providers, patients, and SHI officials in Kenya and Ghana to answer the question: does participation in an SHI scheme affect private providers' ability to serve poorer patient populations with quality health services?

Methods: In-depth interviews were held with 204 providers over three rounds of data collection (2013, 2015, 2017) in Kenya and Ghana. Read More

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December 2018

Challenges of Edible Oils From Farm to Industry: Views of Stakeholders.

Food Nutr Bull 2018 Dec 5:379572118813758. Epub 2018 Dec 5.

1 Food and Nutrition Policy and Planning Research Department, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Objective:: The purpose of this study is to explore stakeholders' views about quality and safety of edible oils from farm to industry and propose policy options to address these challenges.

Methods:: Semistructured, face-to-face interviews were conducted with 11 experts in edible oil industry. Participants were selected through purposive sampling and snowballing. Read More

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December 2018

An Improved YOLOv2 for Vehicle Detection.

Sensors (Basel) 2018 Dec 4;18(12). Epub 2018 Dec 4.

Key Laboratory of Dependable Service Computing in Cyber Physical Society of Ministry of Education, Chongqing University, Chongqing 40004, China.

Vehicle detection is one of the important applications of object detection in intelligent transportation systems. It aims to extract specific vehicle-type information from pictures or videos containing vehicles. To solve the problems of existing vehicle detection, such as the lack of vehicle-type recognition, low detection accuracy, and slow speed, a new vehicle detection model YOLOv2_Vehicle based on YOLOv2 is proposed in this paper. Read More

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December 2018
1 Read

[Honest, Open, Proud: Concept and Efficacy of a peer-led Program to Provide Support with Disclosure Decisions and Coping with Stigma].

Psychiatr Prax 2018 Dec 3. Epub 2018 Dec 3.

Freiberufliche Peer Support Specialist, Zürich, Schweiz.

Background: Due to the stigma associated with mental disorders, many people with mental illness face the difficult choice whether to disclose their illness to others. (Non-)Disclosure is a key reaction in coping with stigma. Disclosure as well as non-disclosure have risks and benefits, depending on the environment and the individual. Read More

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December 2018

Acupuncture improves the facial muscular function in a case of facioscapulohumeral muscular dystrophy.

J Acupunct Meridian Stud 2018 Nov 30. Epub 2018 Nov 30.

Department of Neurology and Neurological Sciences, Stanford University, Stanford, 94305 USA. Electronic address:

Facioscapulohumeral muscular dystrophy (FSHD) is a genetic muscle disorder in which muscles of the face, shoulder blades and upper arms develop gradual and progressive weakness. There is no effective pharmacological treatment currently available for this disorder so far. We had an opportunity to treat a patient with FSHD using acupuncture. Read More

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November 2018
1 Read

Preliminary validation of natural depression in macaques with acute treatments of the fast-acting antidepressant ketamine.

Authors:
Xunxun Chu

Behav Brain Res 2018 Nov 30. Epub 2018 Nov 30.

Interdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou 310012, PR China; Center for Neuroscience, Key Laboratory of Medical Neurobiology of the Ministry of Health of China, School of Medicine, Zhejiang University, Hangzhou 310058, PR China.

Non-human primates have become one of the most important model animals for the investigation of brain diseases because they share a wide-range of genetics and social similarities with human beings. Naturally-evoked depression models in macaques may offer a full spectrum of similarity to human depression states, but they require validation and corroboration of specific phenotypes to depression-associated states before they can be used in research into more effective interventions. It is reported here that depressed cynomolgus monkeys developed in the natural condition display higher levels of typical depressive-like huddling behavior than healthy monkeys. Read More

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November 2018

Validation of the person-centred coordinated care experience questionnaire (P3CEQ).

Int J Qual Health Care 2018 Dec 1. Epub 2018 Dec 1.

Plymouth University, Peninsula Schools of Medicine and Dentistry, NIHR CLAHRC, South West Peninsula (PenCLAHRC), 1 Davy Road, Plymouth Science Park, Plymouth, UK.

Background: Measuring patient experiences of healthcare is increasingly emphasized as a mechanism to measure, benchmark and drive quality improvement, clinical effectiveness and patient safety at both national and local NHS level. Person-centred coordinated care (P3C) is the conjunction of two constructs; person-centred care and care coordination. It is a complex intervention requiring support for changes to organizational structure and the behaviour of professionals and patients. Read More

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December 2018
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