20,296 results match your criteria Eyelid Anatomy


Evaluation of Residual Neuro-Muscular Integrity in the Orbicularis Oculi Muscle After Lower Eyelid Transcutaneous Blepharoplasty According to Reidy Adamson-s Flap.

Aesthetic Plast Surg 2020 May 26. Epub 2020 May 26.

Plastic and Reconstructive Microsurgery, Careggi University Hospital, Viale Giacomo Matteotti 42, 50132, Florence, Italy.

Background: The aging process affects skin, muscle and fat of the eyes in a different manner. Their individual rejuvenation would require specific surgical treatment according to their particular demands during lower eyelid blepharoplasty. This would require the separate management of the skin and the muscle by separating them into two different flaps. Read More

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http://dx.doi.org/10.1007/s00266-020-01783-2DOI Listing

Gross Anatomy, Histological and Histochemical Analysis of the Eyelids and Orbital Glands of the Neonate Pygmy Hippopotamus (Suina: Choeropsis liberiensis or Hexaprotodon liberiensis, Morton 1849) with reference to its habitat.

Anat Rec (Hoboken) 2020 May 23. Epub 2020 May 23.

Wroclaw Zoological Garden, Wróblewskiego 1/5, 51-618, Wrocław, Poland.

The pygmy hippopotamus is phylogenetically related to members of both the Suidae and Cetacea. However, differences in their habitats may have resulted in variation in the anatomy and physiology of the ocular adnexa between these species. Therefore, this study focuses on the identification of accessory organs of the eye, which are typical for the pygmy hippopotamus and are comparable to organs present in mammals related to it. Read More

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http://dx.doi.org/10.1002/ar.24459DOI Listing

Eyelid Complications Associated with Surgery for Periocular Cutaneous Malignancies.

Facial Plast Surg 2020 Apr 15;36(2):166-175. Epub 2020 May 15.

Department of Ophthalmology, Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan.

Periocular skin is highly prone to malignancies, especially basal cell and squamous cell carcinomas. Because of the complex anatomy and eye-protecting functions of the periocular tissues, treatment of these cancers requires special considerations. Mohs micrographic surgery is usually the treatment of choice, whenever possible, in order to enhance margin control while limiting collateral damage to nearby normal structures. Read More

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http://dx.doi.org/10.1055/s-0040-1709515DOI Listing

Treacher Collins syndrome: A novel TCOF1 mutation and monopodial stapes.

Clin Otolaryngol 2020 Apr 29. Epub 2020 Apr 29.

Department of Otolaryngology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Treacher Collins syndrome (TCS: OMIM 154500) is an autosomal dominant craniofacial disorder belonging to the heterogeneous group of mandibulofacial dysostoses.

Objective: To investigate four Treacher Collins syndrome patients of the Sgaw Karen family living in Thailand.

Method: Clinical examination, hearing tests, lateral cephalometric analyses, Computed tomography, whole exome sequencing and Sanger direct sequencing were performed. Read More

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http://dx.doi.org/10.1111/coa.13560DOI Listing
April 2020
2.268 Impact Factor

COVID-19 emergency in the cruise's ship: a case report of conjunctivitis.

Clin Ter 2020 May-Jun;171(3):e189-e191

Department of Public Health and Infectious diseases, Sapienza University of Rome, Italy.

Little is known about the Covid-19 transmission through ocular tissue, and more research needs to be carried out in order to confirm its ability to infect ocular tissue and its pathogenic mechanisms. Covid-19 may be detected in the tears and conjunctival secretions in novel coronavirus pneumonia patients with conjunctivitis. This case report shows a severe viral conjunctivitis in a patient diagnosed with Covid-19 on the Diamond Princess ship, characterized by both red, irritated and swollen eyes, with transparent serous secretions, conjunctival chemosis, pseudomembranes of fibrin and inflammatory cells on the tarsal conjunctiva accompanied by preauricular lymph nodes and enlarged submaxillaries. Read More

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http://dx.doi.org/10.7417/CT.2020.2212DOI Listing

Juberg-Hayward syndrome is a cohesinopathy, caused by mutation in ESCO2.

Eur J Orthod 2020 Apr 7. Epub 2020 Apr 7.

School of Chemistry, Institute of Science, and Center for Biomolecular Structure, Function and Application, Suranaree University of Technology, Nakhon Ratchasima, Thailand.

Background: Juberg-Hayward syndrome (JHS; MIM 216100) is a rare autosomal recessive malformation syndrome, characterized by cleft lip/palate, microcephaly, ptosis, short stature, hypoplasia or aplasia of thumbs, and dislocation of radial head and fusion of humerus and radius leading to elbow restriction.

Objective: To report for the first time the molecular aetiology of JHS.

Patient And Methods: Clinical and radiographic examination, whole exome sequencing, Sanger sequencing, mutant protein model construction, and in situ hybridization of Esco2 expression in mouse embryos were performed. Read More

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http://dx.doi.org/10.1093/ejo/cjaa023DOI Listing
April 2020
1.390 Impact Factor

A New Anatomy Finding of Levator Aponeurosis and Müller Muscle at Pretarsal Plate in Asian Males.

Ophthalmic Plast Reconstr Surg 2020 May/Jun;36(3):311-314

Department of Plastic and Cosmetic Surgery, The Affiliated Friendship Plastic Surgery Hospital of Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.

Purpose: To examine the fine anatomic structures between levator aponeurosis and Müller muscle in front of the tarsus.

Materials And Methods: Postmortem specimens of 6 Chinese males (5 elderly men, aging from 68 to 86 years; 1 child, 10 years old) were used. A 3-μm thickness sagittal section of the central part of the upper eyelid was prepared, and the samples were examined microscopically by using hematoxylin-eosin, Masson trichrome, and anti-smooth muscle actin antibodies staining. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001598DOI Listing

Total and near-total lower eyelid reconstruction with prefabricated orbicularis oculi musculocutaneous island flap.

Dermatol Ther 2020 Apr 3:e13372. Epub 2020 Apr 3.

Department of Plastic Reconstructive and Aesthetic Surgery, Faculty of Medicine, Bulent Ecevit University, Zonguldak, Turkey.

Full thickness lower lid defects are frequently encountered during daily practice. The unique anatomy of the eyelids hinders reconstructive efforts. The aim of the study is to develop an effective and easy procedure for the reconstruction of full thickness defects of the lower eyelid. Read More

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http://dx.doi.org/10.1111/dth.13372DOI Listing

Subtotal Exenteration of the Orbit for Benign Orbital Disease.

J Craniofac Surg 2020 Mar 27. Epub 2020 Mar 27.

Department of Ophthalmology.

Purpose: Total exenteration of the orbit with removal of the eye globe and surrounding tissues is most frequently indicated for malignant tumors. The indications for exenteration of the orbit for benign orbital lesion are rare. Not adequately treated infection of the orbit by systemic antibiotics can lead to destructive changes of soft tissues in the region of the orbit and partial exenteration with eyelid sparing technique is necessary. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006357DOI Listing

Neurotized Free Platysma Flap for Functional Eyelid Reconstruction: A Cadaveric Study of Anatomical Feasibility.

Plast Reconstr Surg 2020 Apr;145(4):1049-1057

Chicago, Ill.; and Cleveland, Ohio From the Division of Plastic and Reconstructive Surgery, Northwestern Feinberg School of Medicine; and the Department of Plastic Surgery, Cleveland Clinic.

Background: Conventional reconstructive options for large full-thickness eyelid defects are limited to static local flaps without replacing the missing orbicularis. The authors' aim is to delineate the platysma neurovascular anatomy for innervated functional eyelid reconstruction.

Methods: Fourteen fresh latex-injected heminecks were dissected. Read More

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http://dx.doi.org/10.1097/PRS.0000000000006648DOI Listing

[Genetic variant analysis of a pedigree affected with lymphedema-distichiasis syndrome].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 Apr;37(4):434-437

Department of Clinical Genetics, Huaian Maternal and Child Health Care Hospital, Huaian, Jiangsu 223002, China.

Objective: To analyze FOXC2 gene variant in a family affected with lymphodema-distichiasis syndrome (LDS).

Methods: Peripheral blood samples were collected for the extraction of DNA and protein. Whole-exome sequencing was carried out to detect variants in the proband. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2020.04.017DOI Listing

Anatomic Features of Head and Neck Keratinocyte Cancer in Virginia.

Dermatol Surg 2020 Mar 18. Epub 2020 Mar 18.

Departments of Oculoplastic Surger, and.

Background: Keratinocyte cancer (KC) patients benefit from early diagnosis. We describe here the anatomy of head/neck KCs to help guide screening efforts.

Objective: To examine lesion frequency and anatomic distribution of head and neck KC. Read More

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http://dx.doi.org/10.1097/DSS.0000000000002370DOI Listing

MR and CT Imaging of the Normal Eyelid and its Application in Eyelid Tumors.

Cancers (Basel) 2020 Mar 12;12(3). Epub 2020 Mar 12.

Department of Radiology, Leiden University Medical Centre, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.

T-staging of most eyelid malignancies includes the assessment of the integrity of the tarsal plate and orbital septum, which are not clinically accessible. Given the contribution of MRI in the characterization of orbital tumors and establishing their relations to nearby structures, we assessed its value in identifying different eyelid structures in 38 normal eyelids and evaluating tumor extension in three cases of eyelid tumors. As not all patients can receive an MRI, we evaluated those same structures on CT and compared both results. Read More

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http://dx.doi.org/10.3390/cancers12030658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139934PMC

Ocular Phenotype of Relaxin Gene Knockout (Rln) Mice.

Curr Eye Res 2020 Mar 16:1-11. Epub 2020 Mar 16.

School of BioSciences, The University of Melbourne, Parkville, Australia.

: To test if relaxin deficiency affects ocular structure and function we investigated expression of relaxin () and RXFP receptors (), and compared ocular phenotypes in relaxin gene knockout () and wild type () mice.: and mRNA expression was detected in ocular tissues of Rln+/+ mice using RT-PCR. The eyes of 11 and 5 male mice were investigated. Read More

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http://dx.doi.org/10.1080/02713683.2020.1737714DOI Listing
March 2020
1.663 Impact Factor

Smartphone screening for neonatal jaundice via ambient-subtracted sclera chromaticity.

PLoS One 2020 2;15(3):e0216970. Epub 2020 Mar 2.

Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.

Jaundice is a major cause of mortality and morbidity in the newborn. Globally, early identification and home monitoring are significant challenges in reducing the incidence of jaundice-related neurological damage. Smartphone cameras are promising as colour-based screening tools as they are low-cost, objective and ubiquitous. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0216970PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7051077PMC

Optical Analysis and Reappraisal of the Peripheral Light Focusing Theory of Nasal Pterygia Formation.

Invest Ophthalmol Vis Sci 2020 02;61(2):42

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Purpose: Pterygia are much more common nasally than temporally. Ultraviolet (UV) radiation is a major risk factor. Coroneo proposed that the nasal preference is caused by the "peripheral light focusing effect," (PLF), in which UV at an oblique angle passes through temporal cornea and is concentrated on and damages nasal limbal stem cells. Read More

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http://dx.doi.org/10.1167/iovs.61.2.42DOI Listing
February 2020

Classification for treatment urgency for the microphthalmia/anophthalmia spectrum using clinical and biometrical characteristics.

Acta Ophthalmol 2020 Feb 25. Epub 2020 Feb 25.

Department of Ophthalmology, Amsterdam Orbital Center, Amsterdam UMC, University of Amsterdam, Amsterdam, Netherlands.

Purpose: Current clinical classifications do not distinguish between the severity of the MICrophthalmia/Anophthalmia (MICA) spectrum with regard to treatment urgency. We aim to provide parameters for distinguishing mild, moderate and severe MICA using clinical and biometrical characteristics.

Methods: We performed a single-centre, cross-sectional analysis of prospective cohort of 58 MICA children from September 2013 to February 2018 seen at the Amsterdam University Medical Center, The Netherlands. Read More

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http://dx.doi.org/10.1111/aos.14364DOI Listing
February 2020

Late-Onset Infection of Resorbable Plates After Multiple Facial Fractures.

J Craniofac Surg 2020 May/Jun;31(3):e280-e282

Department of Plastic and Reconstructive Surgery and Maxillofacial Surgery, Kurume University School of Medicine, Kurume.

In recent years, a variety of resorbable plates have been used for craniofacial fractures. The authors report a case of plate infection that occurred more than 1 year after surgery and was difficult to distinguish from a foreign body reaction. A 19-year-old male suffered fractures of the right zygomatic bone, orbital floor, and left maxilla in a motorcycle accident. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006271DOI Listing
February 2020

Ectropion in Dermatologic Surgery: Exploration and Reconstruction Techniques.

Actas Dermosifiliogr 2020 Apr 6;111(3):229-235. Epub 2020 Feb 6.

Servicio de Dermatología, Complejo Asistencial Universitario de León, León, España.

Ectropion, or eyelid eversion, is the most common form of eyelid malposition. By impairing the eyelid's protective function, ectropion can cause epiphora, lagophthalmos, keratinization, chronic irritation, pain, and ulceration. There are 5 types of ectropion, each with a different cause: congenital, paralytic, involutional, cicatricial, and mechanical. Read More

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http://dx.doi.org/10.1016/j.ad.2019.06.004DOI Listing

[Disorders of the Lacrimal Apparatus, Part 1: Anatomy, Physiology, Diagnostics].

Laryngorhinootologie 2020 Feb 5;99(2):112-125. Epub 2020 Feb 5.

The lacrimal apparatus is a part of the ocular adnexa preserving ocular surface homoeostasis and therefore enabling sufficiant visual functioning. Tear producting tissues, eyelids and efferent tear ducts operate as one functional unit. Pathologic changes consist of inflammatory diseases, congenital disorders, degenerations and neoplasia. Read More

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http://dx.doi.org/10.1055/a-1013-8650DOI Listing
February 2020

Quantitative 3-dimensional Geometry of the Aging Eyelids.

Plast Reconstr Surg Glob Open 2019 Nov 12;7(11):e2512. Epub 2019 Nov 12.

Division of Plastic Surgery, Mount Auburn Hospital, Cambridge, Mass.

Although facial aging is a well-known phenomenon, it has not been comprehensively characterized in 3 dimensions. This study introduces a novel technique for capturing periorbital structures across age groups using 3-dimensional (3D) imaging and point cloud data collection.

Methods: Forty-six white women were divided into 3 age groups: 20-39 years, 40-59 years, and 60+ years. Read More

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http://dx.doi.org/10.1097/GOX.0000000000002512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6908328PMC
November 2019

Japanese encephalitis virus-induced neuropathology in mouse model infected through the conjunctival route.

Indian J Med Res 2019 11;150(5):498-503

Division of Pathology, ICAR-Indian Veterinary Research Institute, Bareilly, Uttar Pradesh, India.

Background & Objectives: Mouse is a preferred animal model for studying pathogenesis of Japanese encephalitis virus (JEV) infections, and different routes of inoculation have been tried. Some neurotropic viruses can reach the brain following infection through ocular route. This study was undertaken to establish JEV-induced clinical disease in mouse model through conjunctival route and document the neuropathological effects. Read More

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http://dx.doi.org/10.4103/ijmr.IJMR_2078_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6977363PMC
November 2019

Histological and immunohistochemical characterization of the porcine ocular surface.

PLoS One 2020 13;15(1):e0227732. Epub 2020 Jan 13.

Ocular Surface Group, IOBA - University of Valladolid, Valladolid, Spain.

The ocular surface of the white domestic pig (Sus scrofa domestica) is used as a helpful model of the human ocular surface; however, a complete histological description has yet to be published. In this work, we studied porcine eyeballs with intact eyelids to describe and characterize the different structures that form the ocular surface, including the cornea and conjunctiva that covers the bulbar sclera, tarsi, and the nictitating membrane. We determined the distribution of goblet cells of different types over the conjunctiva and analyzed the conjunctival-associated lymphoid tissue (CALT). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0227732PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957219PMC

Radioiodine therapy and Graves' disease - Myths and reality.

PLoS One 2020 13;15(1):e0226495. Epub 2020 Jan 13.

Department of Nuclear Medicine, Warsaw Medical University, Warsaw, Poland.

Introduction: Autoimmune reactions in Graves' disease (GD) occur not only in the thyroid gland, but also in the orbital connective tissue, eyelids, extraocular muscles. The occurrence of orbitopathy in the course of GD is influenced by environmental factors, e.g. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0226495PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6957158PMC

Bilateral nevus comedonicus of the eyelids: An unusual cause of ptosis and ectropion.

Am J Ophthalmol Case Rep 2020 Mar 17;17:100579. Epub 2019 Dec 17.

Department of Ophthalmology, Centre Hospitalier Universitaire de Martinique, Martinique, French West Indies, France.

Purpose: Nevus comedonicus is a rare developmental abnormality of the infundibulum of the hair follicle.

Observation: We report here an unusual case of bilateral extensive nevus comedonicus of the eyelids complicated by bilateral ptosis and ectropion of the lower eyelids. Blepharoplasty was performed on both upper eyelids. Read More

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http://dx.doi.org/10.1016/j.ajoc.2019.100579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938988PMC

Whale tear glands in the bowhead and the beluga whales: Source and function.

J Morphol 2020 Mar 6;281(3):316-325. Epub 2020 Jan 6.

Department of Anatomy and Neurobiology, Northeast Ohio Medical University, Rootstown, Ohio.

Orbital glands are found in many tetrapod vertebrates, and are usually separate structures, consisting of individual glands lying in the eyelids and both canthi of the orbit. In cetaceans, however, the orbital glandular units are less distinct and have been described by numerous authors as a single, periorbital mass. There are few histochemical and immunhistochemical studies to date of these structures. Read More

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http://dx.doi.org/10.1002/jmor.21099DOI Listing

SK2 channels in cerebellar Purkinje cells contribute to excitability modulation in motor-learning-specific memory traces.

PLoS Biol 2020 01 6;18(1):e3000596. Epub 2020 Jan 6.

Department of Neurobiology, University of Chicago, Chicago, Illinois, United States of America.

Neurons store information by changing synaptic input weights. In addition, they can adjust their membrane excitability to alter spike output. Here, we demonstrate a role of such "intrinsic plasticity" in behavioral learning in a mouse model that allows us to detect specific consequences of absent excitability modulation. Read More

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http://dx.doi.org/10.1371/journal.pbio.3000596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6964916PMC
January 2020

Herbert Pits in Trachoma Infection.

Mayo Clin Proc 2020 01;95(1):134-135

Cornea, Cataract, and Refractive Surgery Division, The Wilmer Eye Institute, The Johns Hopkins University Institutions, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2019.10.027DOI Listing
January 2020

Punctal dilatation and non-incisional canalicular curettage in the management of infectious canaliculitis.

Orbit 2020 Jan 3:1-5. Epub 2020 Jan 3.

Govindram Seksaria Institute of Dacryology, L.V. Prasad Eye Institute, Hyderabad, India.

: To describe the outcomes of punctal dilatation and non-incisional canalicular curettage in patients with infectious canaliculitis.: A retrospective analysis of 53 canaliculi of 47 eyes of 46 consecutive patients diagnosed with canaliculitis was performed from November 2015 to December 2018. All patients were treated with punctal dilatation and a non-incisional canalicular curettage. Read More

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http://dx.doi.org/10.1080/01676830.2019.1704797DOI Listing
January 2020

Case report of periorbital metastasis from rectal cancer.

Medicine (Baltimore) 2020 Jan;99(1):e18479

Department of Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Gwangjin-gu, Seoul, Republic of Korea.

Introduction: Periorbital metastasis of colorectal cancer is rare. Therefore, herein, we report a patient with rectal cancer who presented with periorbital metastasis without any systemic metastasis.

Patient Concerns: The patient was a 57-year-old man who had a painless nodule on his left eyelid. Read More

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http://dx.doi.org/10.1097/MD.0000000000018479DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946509PMC
January 2020

Evaluation of Intraarterial Thrombolysis in Treatment of Cosmetic Facial Filler-Related Ophthalmic Artery Occlusion.

Plast Reconstr Surg 2020 01;145(1):42e-50e

Beijing, People's Republic of China From the Departments of Burn and Plastic Surgery, Radiology, and Ophthalmology, The Fourth Medical Center of Chinese PLA General Hospital.

Background: With an increase in recent years in the number of people receiving cosmetic facial injection treatments of hyaluronic acid, the incidence of hyaluronic acid embolism has also increased commensurately. Hyaluronic acid embolism leads to serious complications, including blindness, eye and eyelid movement disorders, skin necrosis, and cerebral embolism. However, there is a lack of robust clinical evidence regarding the benefits of treatment for hyaluronic acid embolism by intraarterial thrombolysis therapy. Read More

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http://dx.doi.org/10.1097/PRS.0000000000006313DOI Listing
January 2020

The Nasal Gland in Turkeys (): Anatomy, Histology, and Ultrastructure.

Avian Dis 2019 12;63(4):551-558

California Animal Health and Food Safety Laboratory System, Tulare Branch, School of Veterinary Medicine, University of California-Davis, 18830 Road 112 Tulare, CA 93274-9042.

This study provides a detailed description of the major morphoanatomic and ultrastructural features of the nasal gland in turkeys. In this avian species, nasal or salt glands are bilateral, pale pink, elongated to spindle-shaped, serous, tubuloalveolar structures, with a mean length ranging from 0.64 ± 0. Read More

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http://dx.doi.org/10.1637/aviandiseases-D-19-00088DOI Listing
December 2019

Thoracic tumor resection combined with SVC replacement using autologous pericardium.

World J Surg Oncol 2019 Dec 21;17(1):227. Epub 2019 Dec 21.

Department of Thoracic Surgery, Jiangxi Province Tumor Hospital, No. 519 Beijing east Road, Nanchang, 330006, Jiangxi, China.

Background: Invasion of the superior vena cava (SVC) by thoracic tumors and occurrence of SVC syndrome are often encountered in clinical practice; but the prognosis in these cases is poor. Replacement of the SVC with autologous pericardial tissue is rarely performed. In this study, we sought to investigate the postoperative outcomes of this rare procedure. Read More

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http://dx.doi.org/10.1186/s12957-019-1769-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6925868PMC
December 2019

Effects of Regorafenib, a Multi-Kinase Inhibitor, on Conjunctival Scarring in a Canine Filtration Surgery Model in Comparison with Mitomycin-C.

Int J Mol Sci 2019 Dec 20;21(1). Epub 2019 Dec 20.

Department of Ophthalmology, Osaka Medical College, Takatsuki-City, Osaka 569-8686, Japan.

Regorafenib eye drops were developed for treating age-related macular degeneration. This study aimed to investigate the effects of this multi-kinase inhibitor on intraocular pressure (IOP), bleb formation, and conjunctival changes in a canine filtration surgery model. Glaucoma filtration surgery models were created in 24 eyes of 24 beagles. Read More

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http://dx.doi.org/10.3390/ijms21010063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982091PMC
December 2019

Supraorbital vs Endo-Orbital Routes to the Lateral Skull Base: A Quantitative and Qualitative Anatomic Study.

Oper Neurosurg (Hagerstown) 2018 11;15(5):567-576

Division of Neurosurgery, Department of Neurosciences, Reproductive and Odon-tostomatological Sciences, Univers-itá degli Studi di Napoli Federico II, Naples, Italy.

Background: Various extensions of the supraorbital approach reach the lateral and parasellar middle cranial fossa regions by removing the orbital rim and greater/lesser sphenoid wings. Recent proposals of a purely endoscopic ventral transorbital pathway to these regions heighten the need to compare these surgical windows.

Objective: To detail the lateral and parasellar middle cranial fossa regions and quantify exposures by 2 surgical windows (transcranial and transorbital) through anatomic study. Read More

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http://dx.doi.org/10.1093/ons/opx256DOI Listing
November 2018

The Role of Overriding Preseptal Orbicularis Oculi Muscle in Development of Involutional Lower Eyelid Entropion: Microscopic Viewpoints.

J Craniofac Surg 2020 Mar/Apr;31(2):573-576

Department of Oculoplastic, Orbital & Lacrimal Surgery, Aichi Medical University Hospital, Nagakute.

The aim of this study was to demonstrate the extent of preseptal orbicularis oculi muscle (OOM) override onto the pretarsal OOM in the lower eyelids. In this experimental microscopic study, 22 exenterated specimens from 22 Japanese cadavers were prepared as full-thickness sagittal sections. All exenterated specimens were devoid of lower eyelid entropion. Read More

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http://dx.doi.org/10.1097/SCS.0000000000006068DOI Listing
December 2019

How to best utilize the line of ligaments and the surface volume coefficient in facial soft tissue filler injections.

J Cosmet Dermatol 2020 Feb 15;19(2):303-311. Epub 2019 Dec 15.

Division of Anatomy, Department of Medical Education, Albany Medical College, Albany, NY, USA.

Background: Recent advances in facial anatomy have increased our understanding of facial aging and where to best position facial soft tissue fillers.

Aim: Aim of this study was to investigate a novel injection protocol which makes use of concepts like the line of ligaments or the surface - volume coefficient.

Materials And Methods: A total of 306 Caucasian patients (270 females, mean age 45. Read More

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http://dx.doi.org/10.1111/jocd.13245DOI Listing
February 2020

Management of orbital complications in palatomaxillary reconstruction: A review of preemptive and corrective measures.

Head Neck 2020 Mar 13;42(3):556-568. Epub 2019 Dec 13.

THANC (Thyroid, Head and Neck Cancer) Foundation, New York, New York.

Background: Reconstruction of orbit-sparing palatomaxillary defects requires consideration of globe dystopia, orbital volume, eyelid position and function, and the nasolacrimal system to preserve and optimize vision, globe protection, and appearance. We describe the fundamentals of orbital and eyelid anatomy, common orbital complications related to palatomaxillary reconstruction, and preemptive and corrective surgical techniques to be utilized during and after globe-sparing palatomaxillary reconstruction.

Methods: We present a review of the literature supplemented by clinical case examples. Read More

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http://dx.doi.org/10.1002/hed.26015DOI Listing

Ocular alignment, media, and eyelid disorders in Down syndrome.

Strabismus 2020 03 12;28(1):42-48. Epub 2019 Dec 12.

Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran.

: Determining the age and gender distribution of ocular disorders in Down syndrome patients aged 10 to 30 years.: In this study, 226 of 250 invited patients through special needs schools, the National Down Syndrome Society, and relevant nonprofit organizations were included. In Noor Eye Hospital, the patients underwent a complete eye examination by a general ophthalmologist and suspect cases were reexamined by a sub-specialist. Read More

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http://dx.doi.org/10.1080/09273972.2019.1699582DOI Listing

Repeatability of ocular surface vessel density measurements with optical coherence tomography angiography.

BMC Ophthalmol 2019 Dec 10;19(1):248. Epub 2019 Dec 10.

Department of Ophthalmology, First Affiliated Hospital, College of Medicine, Zhejiang University, Zhejiang, Hangzhou, China.

Background: To determine the repeatability of measurements of ocular surface vessel density in normal and diseased eyes using optical coherence tomography angiography (OCTA).

Methods: Ten normal eyes, 10 pinguecula eyes, and 10 pterygium eyes of 30 volunteers were subjected to OCTA (AngioVue Imaging System, Optovue, Inc.). Read More

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http://dx.doi.org/10.1186/s12886-019-1255-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902509PMC
December 2019

Trichoblastoma of lid: a masquerading tumour.

BMJ Case Rep 2019 Dec 8;12(12). Epub 2019 Dec 8.

Ophthalmology, Ruby Eye Hospital, Berhampur, Odisha, India.

A 62-year-old woman came to our hospital with complaints of painless gradual increase in dark coloured mass along inner canthus of the right eye. The surface of the mass was rough with a well-defined margin. No other systemic abnormality was detected. Read More

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http://dx.doi.org/10.1136/bcr-2019-232599DOI Listing
December 2019

Biallelic Deletion of in Mice Leads to Anophthalmia and Severe Eye Malformation.

Int J Mol Sci 2019 Dec 5;20(24). Epub 2019 Dec 5.

Cancer Research Institute, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.

Peroxidasin (PXDN) is a unique peroxidase containing extracellular matrix motifs and stabilizes collagen IV networks by forming sulfilimine crosslinks. PXDN gene knockout in () and results in the demise at the embryonic and larval stages. PXDN mutations lead to severe eye disorders, including microphthalmia, cataract, glaucoma, and anterior segment dysgenesis in humans and mice. Read More

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http://dx.doi.org/10.3390/ijms20246144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941041PMC
December 2019

Ocular surface and tear film changes in workers exposed to organic solvents used in the dry-cleaning industry.

PLoS One 2019 9;14(12):e0226042. Epub 2019 Dec 9.

School of Optometry and Vision Science, The University of New South Wales, Sydney, Australia.

Workers in the dry-cleaning industry are exposed to organic solvents that may cause eye irritation and tear film changes. Objective To quantify changes in the ocular surface and tear film in dry cleaners exposed to organic solvents and associate these changes with ocular irritation as reported in a symptom questionnaire for dry eye diagnosis. Methods This was a case and control study in which the characteristics and eye-irritation symptoms were compared between two groups of 62 participants that were either exposed or not exposed to organic solvents. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0226042PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901226PMC

Meibomian gland dysfunction (MGD), as diagnosed by non-contact infrared Meibography, in dogs with ocular surface disorders (OSD): a retrospective study.

BMC Vet Res 2019 Dec 5;15(1):443. Epub 2019 Dec 5.

Turin Veterinary Centre (CVT), Lungo Dora Colletta 147, 10153, Torino, Italy.

Background: Meibomian gland dysfunction (MGD) is one of the possible conditions underlying ocular surface disorders (OSD). Prevalence of MGD in dogs affected by OSD has not yet been reported. We aimed to evaluate the prevalence of MGD among OSD canine patients, which had been assessed by non-contact infrared meibography and interferometry, and to identify MGD associated factors that might guide its diagnosis. Read More

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http://dx.doi.org/10.1186/s12917-019-2203-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896755PMC
December 2019

Changes in Human Tear Proteome Following Topical Treatment of Dry Eye Disease: Cyclosporine A Versus Diquafosol Tetrasodium.

Invest Ophthalmol Vis Sci 2019 12;60(15):5035-5044

Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea.

Purpose: To compare the changes in human tear proteome and clinical effects following topical cyclosporine A (CsA) 0.05% or diquafosol tetrasodium (DQS) 3% treatment of dry eye disease (DED), and to identify biomarkers for determining disease severity and treatment effectiveness in DED.

Methods: A total of 18 patients were diagnosed with non-Sjögren DED. Read More

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http://dx.doi.org/10.1167/iovs.19-27872DOI Listing
December 2019
3.404 Impact Factor

Providing Optimal Rejuvenation to the Periocular Area Using Botulinum Toxin A Neuromodulators and Hyaluronic Acid Dermal Fillers.

Authors:
Rachel Varga

Plast Surg Nurs 2019 Oct/Dec;39(4):119-124

Rachel Varga, BScN, RN, is an aesthetic nurse, practicing in Hillside, Victoria, British Columbia, Canada. She is a clinical instructor, international speaker, trainer for Alladina Medical Ltd, writer, and founder of Rachel Varga Inc, specializing in anti-aging education for both the client and the clinician.

The periorbital area is the first area of the face to show signs of aging. To provide safe and natural looking rejuvenation of the delicate eyelids, and supporting structures, an advanced understanding of anatomy, ideal facial proportions, and the most effective methods for rejuvenation is discussed. Periocular rejuvenation is particularly challenging due to the intricate and delicate anatomy of the periocular area. Read More

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http://dx.doi.org/10.1097/PSN.0000000000000279DOI Listing

A Survey of Surgical Techniques in Pterygium, Thailand 2016.

Asia Pac J Ophthalmol (Phila) 2019 Nov-Dec;8(6):476-480

Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Background: Pterygium causes a significant ocular disturbance which usually requires surgical removal; however, recurrence of pterygium after surgery frustrates both patients and surgeons. This survey aimed to determine the current surgical approaches in primary and recurrent pterygium, and the ideal surgical techniques among Thai ophthalmologists.

Methods: Questionnaires were sent to 1150 ophthalmologists who are members of Royal College of Ophthalmologists of Thailand (RCOPT). Read More

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http://dx.doi.org/10.1097/01.APO.0000605100.25659.f7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903370PMC

Neurotized Platysma Graft: A New Technique for Functional Reanimation of the Eye Sphincter in Longstanding Facial Paralysis.

Plast Reconstr Surg 2019 12;144(6):1061e-1070e

Rio de Janeiro, Brazil From the Department of Reconstructive Microsurgery, HSE; and the Clínica de Cirurgia Plástica Rio de Janeiro.

Background: In 1984, Terzis reported on the potential use of a free platysma muscle transfer to reanimate the orbicularis oculi in longstanding paralysis of this unit. However, the vascularized platysma flap proved difficult to transfer, and this technique is not widely used today. In the present study, the authors have described the technique involving grafting of the platysma muscle to restore eyelid function and retrospectively discussed its clinical outcomes. Read More

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http://dx.doi.org/10.1097/PRS.0000000000006296DOI Listing
December 2019