599,292 results match your criteria Eye London England[Journal]


[Diagnostic Strategy and Therapeutic Dilemma in Acute Posterior and Panuveitis].

Klin Monbl Augenheilkd 2019 Feb 14. Epub 2019 Feb 14.

Augenklinik, Universitätsspital Basel, Schweiz.

Acute posterior and panuveitis mostly affect younger patients and affect both eyes in more than half of cases. Because of the severe consequences in the clinical course, rapid and broad differential diagnosis are critical steps. Permanent loss of vision after a delay in starting therapy and the initiation of ineffective treatment are both serious risks. Read More

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http://dx.doi.org/10.1055/a-0828-7395DOI Listing
February 2019

[Ocular Phenotype and Complications in Patients with Tuberous Sclerosis Complex (TSC)].

Klin Monbl Augenheilkd 2019 Feb 14. Epub 2019 Feb 14.

Augenklinik, UniversitätsSpital Zürich, Schweiz.

Background: Evaluation and comparison of the ocular phenotype in patients diagnosed with tuberous sclerosis complex (TSC). Analysis of ocular complications during follow-up.

Patients And Methods: A retrospective chart review was performed of patients with TSC who had received an ocular examination at the eye clinic of the University Hospital Zurich. Read More

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http://dx.doi.org/10.1055/a-0804-1816DOI Listing
February 2019

The Heimann-Bielschowsky Phenomenon: A Retrospective Case Series and Literature Review.

Klin Monbl Augenheilkd 2019 Feb 14. Epub 2019 Feb 14.

Ophthalmology, Jules Gonin Eye Hospital, Lausanne, Switzerland.

Background: The Heimann-Bielschowsky phenomenon (HBP) is an unusual form of monocular vertical pendular nystagmus and is usually asymptomatic. It always occurs in an eye with longstanding, profound visual loss. Reports of HBP are few and HBP is probably underdiagnosed. Read More

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http://dx.doi.org/10.1055/a-0829-6001DOI Listing
February 2019

[Prophylaxis of Recurrent Cytomegalovirus Uveitis with Topical Ganciclovir].

Klin Monbl Augenheilkd 2019 Feb 14. Epub 2019 Feb 14.

Augenklinik, UniversitätsSpital Zürich, Universität Zürich, Schweiz.

Purpose: Cytomegalovirus (CMV) can cause recurrent or chronic hypertensive anterior uveitis in immunocompetent patients. Antiviral treatment options include topical ganciclovir or systemic valganciclovir. However, recurrences are common after stopping treatment. Read More

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http://dx.doi.org/10.1055/a-0816-5598DOI Listing
February 2019

Effectiveness of Scleral Buckling with a Wide-Field Surgical Microscope and Chandelier Illumination in Retinal Detachment Repair.

Ophthalmologica 2019 Feb 14:1-7. Epub 2019 Feb 14.

Department of Ophthalmology, College of Medicine, Hallym University, Hwaseong, Republic of Korea.

Purpose: To assess treatment efficacy of scleral buckling surgery with wide-field surgical microscope and 27-gauge (G) chandelier illumination for rhegmatogenous retinal detachment (RRD).

Methods: This study is a retrospective chart review of 29 eyes in 29 patients with RRD who underwent scleral buckling surgery with a wide-field surgical microscope and 27-G chandelier illumination fiber inserted into the sclera at the pars plana. Results are expressed as mean ± standard deviation. Read More

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http://dx.doi.org/10.1159/000496165DOI Listing
February 2019

Pullulan-derived nanocomposite hydrogels for wastewater remediation: Synthesis and characterization.

J Colloid Interface Sci 2019 Feb 7;542:253-262. Epub 2019 Feb 7.

School of Chemical Engineering, Nanjing University of Science & Technology, Nanjing 210094, China. Electronic address:

Polysaccharide is a renewable, biocompatible and biodegradable material that has received considerable attention. In this work, a series of polysaccharide gels were synthesized from the chemical cross-linking of pullulan with diglycerols. The effects of the diglycerol chain length on the performance of the gels were evaluated by XRD, TGA, SEM, rheological testings and swelling measurements. Read More

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http://dx.doi.org/10.1016/j.jcis.2019.02.025DOI Listing
February 2019

Inhibition of the alternative complement pathway accelerates repair processes in the murine model of choroidal neovascularization.

Mol Immunol 2019 Feb 11;108:8-12. Epub 2019 Feb 11.

Department of Ophthalmology and Microbiology, Medical University of South Carolina, Charleston, SC 29425, United States; Department of Ralph H. Johnson VA Medical Center, Division of Research, Charleston, SC 29401, United States. Electronic address:

Age-related macular degeneration (AMD) is the leading cause of blindness in the US. Polymorphisms in complement components are associated with increased AMD risk, and it has been hypothesized that an overactive complement system is partially responsible for AMD pathology. Choroidal neovascularization (CNV) has two phases, injury/angiogenesis and repair/fibrosis. Read More

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http://dx.doi.org/10.1016/j.molimm.2019.02.001DOI Listing
February 2019

Mucoadhesive olaminosomes: A novel prolonged release nanocarrier of agomelatine for the treatment of ocular hypertension.

Int J Pharm 2019 Feb 11. Epub 2019 Feb 11.

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt. Electronic address:

Mucoadhesive olaminosomes are novel nanocarriers designed to control agomelatine release and enhance its bioavailability. Olaminosomes were prepared using oleic acid, oleylamine and sorbitan monooleate adopting thin film hydration technique. Chitosan HCl was added to impart the mucoadhesive properties to the olaminosomes. Read More

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http://dx.doi.org/10.1016/j.ijpharm.2019.01.070DOI Listing
February 2019

MiRNA as biomarker for uveitis - A systematic review of the literature.

Gene 2019 Feb 11. Epub 2019 Feb 11.

Eye Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia. Electronic address:

Aim: A systematic review of miRNA profiling studies in uveitis.

Methods: Literature search strategy - Pubmed central central database, using miRNA/microRNA and intraocular inflammation/uveitis as keywords.

Results: We found twenty publications regarding the experimental and clinical use of miRNA in uveitis, published between 2011 and 2018. Read More

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http://dx.doi.org/10.1016/j.gene.2019.02.004DOI Listing
February 2019

Corneal Substructure Dosimetry Predicts Corneal Toxicity in Patients with Uveal Melanoma Treated with Proton Beam Therapy.

Int J Radiat Oncol Biol Phys 2019 Feb 11. Epub 2019 Feb 11.

Department of Radiation Oncology, University of Washington School of Medicine, Seattle, WA 98195, USA.

Purpose: The present study examines the relationship between dose to corneal substructures and incidence of corneal toxicity within six months of proton beam therapy (PBT) for uveal melanoma. We aim to develop clinically meaningful dose constraints that can be used to mitigate corneal toxicity.

Methods And Materials: Ninety-two patients were treated with PBT between 2015 and 2017 and evaluated for grade 2+ (GR2+), intervention-requiring corneal toxicity in our prospectively maintained database. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2019.02.005DOI Listing
February 2019

Short-Term Effects of Intravitreal Bevacizumab in Contrast Sensitivity of Patients with Diabetic Macular Edema and Optimizing Glycemic Control.

Diabetes Res Clin Pract 2019 Feb 11. Epub 2019 Feb 11.

Division of Ophthalmology, University of São Paulo, São Paulo Medical School, São Paulo, Brazil.

Aims: To analyze contrast sensitivity of intravitreal bevacizumab injections with optimizing glycemic control versus optimizing glycemic control (in combination with sham injections) in eyes with diabetic macular edema (DME) DESIGN: Prospective, interventional, masked, randomized controlled trial.

Methods: Forty-one eyes of 34 patients with type 2 diabetes mellitus and DME with glycated hemoglobin (HbA1c) <11% received either intravitreal bevacizumab injection (Group 1) or sham injection (Group 2) at 0 and 6 weeks along with optimizing glycemic control. Mean change in best-corrected visual acuity (BCVA), contrast sensitivity (CS), optical coherence tomography (OCT)-measured by central macular thickness (CMT) were compared and correlated at baseline, 2, 6 and 12 weeks. Read More

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http://dx.doi.org/10.1016/j.diabres.2019.02.002DOI Listing
February 2019

Ginsenoside Rg1 protects human retinal pigment epithelial ARPE-19 cells from toxicity of high glucose by up-regulation of miR-26a.

Life Sci 2019 Feb 11. Epub 2019 Feb 11.

Department of Ophthalmology, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, Zhengzhou 450000, China. Electronic address:

Aims: The therapeutic strategies for diabetic retinopathy (DR) are disappointing. Ginsenoside Rg1 (Rg1) extracted from Panax ginseng can induce glucose uptake and lower oxidative stress. We aimed to explore the effect of Rg1 on DR using human retinal pigment epithelium cells (ARPE-19). Read More

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http://dx.doi.org/10.1016/j.lfs.2019.02.021DOI Listing
February 2019

The genetic influence on corticosteroid-induced ocular hypertension: A field positioned for discovery.

Am J Ophthalmol 2019 Feb 11. Epub 2019 Feb 11.

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114. Electronic address:

Purpose: To provide evidence that corticosteroid-induced ocular hypertension has a genetic component.

Design: Evidence-based Perspective.

Methods: We conducted a comprehensive literature search for studies exploring genetic influences on intraocular pressure responses to corticosteroid treatment. Read More

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http://dx.doi.org/10.1016/j.ajo.2019.02.001DOI Listing
February 2019

Comparison of Biphasic vs Static Oxygen Saturation Targets Among Infants With Retinopathy of Prematurity.

JAMA Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio.

Importance: The Surfactant, Positive Pressure, and Pulse Oximetry Randomized Trial (SUPPORT) demonstrated that static low oxygen saturation decreased retinopathy of prematurity (ROP) but increased mortality compared with static high oxygen saturation cohorts.

Objective: To compare outcomes of a biphasic oxygen protocol with static targets recommended by SUPPORT.

Design, Setting, And Participants: Retrospective cohort study comparing biphasic vs static standards 41 months prior to and 42 months after a change from biphasic to static SUPPORT standards at a level III neonatal intensive care unit (Fairview Hospital, Cleveland, Ohio). Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2018.7021DOI Listing
February 2019

Retinal Hemorrhages in a Patient With Petechiae.

JAMA Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Department of Ophthalmology, Baylor College of Medicine, Cullen Eye Institute, Houston, Texas.

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http://dx.doi.org/10.1001/jamaophthalmol.2018.6220DOI Listing
February 2019

The Argument for Sterile Loading of All Intravitreal Injections and the Benefit of Replicated Results.

JAMA Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jamaophthalmol.2018.7089DOI Listing
February 2019

Macrodendrite in a Patient With Herpes Simplex Virus Keratitis.

JAMA Ophthalmol 2019 Feb 14;137(2):e183979. Epub 2019 Feb 14.

Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jamaophthalmol.2018.3979DOI Listing
February 2019

Apocrine Hydrocystoma-Lantern of the Eye.

JAMA Ophthalmol 2019 Feb 14;137(2):e183975. Epub 2019 Feb 14.

Department of Ocular Pathology, Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

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http://dx.doi.org/10.1001/jamaophthalmol.2018.3975DOI Listing
February 2019

Choroidal Rupture Through the Fovea With Overlying Traumatic Epiretinal Membrane.

JAMA Ophthalmol 2019 Feb 14;137(2):e183971. Epub 2019 Feb 14.

Department of Ophthalmology, Ben Taub General Hospital, Houston, Texas.

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http://dx.doi.org/10.1001/jamaophthalmol.2018.3971DOI Listing
February 2019

Ocular Surface Squamous Neoplasia Hiding in Primary Acquired Melanosis.

JAMA Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami, Miami, Florida.

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http://dx.doi.org/10.1001/jamaophthalmol.2018.6503DOI Listing
February 2019

Reevaluating a Standardized Sedation Weaning Protocol for Pediatric Laryngotracheal Reconstruction for Continuous Quality Improvement.

JAMA Otolaryngol Head Neck Surg 2019 Feb 14. Epub 2019 Feb 14.

Department of Otolaryngology-Head and Neck Surgery, Massachusetts Eye & Ear Infirmary, Boston, Masschusetts.

Importance: Health care organizations are complex and evolving systems. To date, longitudinal evaluation to ensure the sustainability of quality improvement (QI) initiatives has been missing from the otolaryngology literature. We sought to reassess perioperative management of laryngotracheal reconstruction, which requires adequate sedation. Read More

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http://dx.doi.org/10.1001/jamaoto.2018.4348DOI Listing
February 2019

Assessment of Ideal Dimensions of the Ears, Nose, and Lip in the Circles of Prominence Theory on Facial Beauty.

Authors:
Philip Young

JAMA Facial Plast Surg 2019 Feb 14. Epub 2019 Feb 14.

Aesthetic Facial Plastic Surgery, Bellevue, Washington.

Importance: A theory on facial beauty might allow clinicians to achieve better results.

Objectives: To find the ideal vertical position of the ears, total lip length, lip pucker length, distance between the irises, and starting point for the nasal radix.

Design, Setting, And Participants: In this subjective survey, 11 sets of 43 total digitally adjusted pictures (DAPs) and line drawings of actual faces were ranked based on attractiveness by 419 clients at a facial plastic surgery clinic. Read More

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http://dx.doi.org/10.1001/jamafacial.2018.1797DOI Listing
February 2019

Abnormal intrinsic functional network hubs and connectivity following peripheral visual loss because of inherited retinal degeneration.

Neuroreport 2019 Mar;30(4):295-304

Eye Center, Renmin Hospital of Wuhan University, Wuhan, Hubei Province.

Previous neuroimaging studies have shown that the long-term effects of peripheral vision loss lead to functional and morphological reorganization in visual cortices. However, it has not been determined whether whole-brain functional network centrality changes occur during peripheral vision loss. This study aimed to investigate functional network centrality and connectivity changes in individuals with peripheral vision loss because of retinitis pigmentosa (RP) by using voxel-wise degree centrality (DC) and seed-based resting-state functional connectivity (rsFC) methods. Read More

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http://dx.doi.org/10.1097/WNR.0000000000001200DOI Listing

Hypertensive ocular disease in cats: A guide to fundic lesions to facilitate early diagnosis.

Authors:
Jenny Carter

J Feline Med Surg 2019 Jan;21(1):35-45

Auckland, New Zealand.

Practical Relevance:: Systemic hypertension is common in older cats and can result in damage to organs with a rich arteriolar supply such as the eyes, kidneys, myocardium and brain. Hypertensive disease in these organs is known as target organ damage (TOD). Disease in the eye resulting from hypertension is the most easily identifiable form of TOD and can often be the reason the cat is presented to the veterinarian. Read More

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http://dx.doi.org/10.1177/1098612X18818668DOI Listing
January 2019

Temporomandibular Disorder: An Important Cause of Temporal Headache in Patients Unlikely to Have Giant Cell Arteritis.

Semin Ophthalmol 2019 Feb 14:1-5. Epub 2019 Feb 14.

a Tennent Institute of Ophthalmology , Gartnavel General Hospital , Glasgow , UK.

Introduction: Temporal headache often results in an Ophthalmology referral to rule out giant cell arteritis (GCA). When clinical suspicion of GCA is low, alternative diagnoses should be considered. Temporomandibular disorder (TMD) commonly causes a temporal headache. Read More

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http://dx.doi.org/10.1080/08820538.2019.1578383DOI Listing
February 2019

The drug price iceberg: more than meets the eye.

Am J Manag Care 2019 Feb;25(2):57-58

University of Michigan, 2800 Plymouth Rd, Bldg 16, Fl 4, 016-400S-25, Ann Arbor, MI 48109-2800. Email:

When it comes to the political iceberg of drug prices, there is more below the surface. Policies that reduce prices but do not lower consumers' out-of-pocket costs will not address the main challenge facing most Americans. Read More

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February 2019

Recommendations for ultrasound examination in ophthalmology. Part II: Orbital ultrasound.

J Ultrason 2018 ;18(75):349-354

Imperial College NHS Trust, Western Eye Hospital , London , UK.

Pathological processes within the orbits are a heterogeneous group of diseases of various etiologies, clinical pictures and therapy models. Due to poor access to the orbits in a clinical examination, imaging plays a significant role in both diagnosis and treatment monitoring in patients with an orbital pathology. One of such imaging modalities is ultrasonography. Read More

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http://dx.doi.org/10.15557/JoU.2018.0051DOI Listing
January 2018

Recommendations for ultrasound examination in ophthalmology. Part I: Ultrabiomicroscopic examination.

J Ultrason 2018 ;18(75):344-348

Vilnius University, Faculty of Medicine , Vilnius , Lithuania ; Center of Eye Diseases in Vilnius University Hospital Santaros Klinikos , Vilnius , Lithuania.

Range of ultrasounds used in medical imaging is between 2 and 80 MHz. The highest frequencies are applied in medical imaging of an anterior segment of an eyeball. This paper covers the newest method of ultrasound imaging - an ultrabiomicroscopic examination. Read More

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http://dx.doi.org/10.15557/JoU.2018.0050DOI Listing
January 2018

A Case of Radioactive Iodine Uptake Found in Artificial Eye.

Clin Nucl Med 2019 Feb 8. Epub 2019 Feb 8.

From the Department of Nuclear Medicine and Molecular Imaging, Ajou University School of Medicine, Suwon, South Korea.

Radioactive iodine (RAI) therapy is widely used as an adjunctive treatment in patients with differentiated thyroid cancer. Although I has high avidity in the functioning thyroid, and in differentiated thyroid cancer lesions, physiological and nonspecific uptake of I in healthy or benign tissue may contribute to false-positive findings on an I scan. Here, we present an interesting image of RAI uptake in the eye region post-RAI treatment, which has been identified as tear contamination in the artificial eye. Read More

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http://dx.doi.org/10.1097/RLU.0000000000002486DOI Listing
February 2019
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Quantitative Multimodal Assessment of Concussion Recovery in Youth Athletes.

Clin J Sport Med 2019 Feb 11. Epub 2019 Feb 11.

The Micheli Center for Sports Injury Prevention, Waltham, Massachusetts.

Objective: To evaluate recovery trajectories among youth athletes with a concussion and healthy controls across different domains using a quantitative and multifaceted protocol.

Study Design: Prospective repeated measures.

Participants: Youth athletes diagnosed with a concussion between the ages of 8 and 18 years were evaluated (1) within 10 days after injury, (2) approximately 3 weeks after injury, and (3) after return-to-play clearance. Read More

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http://dx.doi.org/10.1097/JSM.0000000000000722DOI Listing
February 2019

IMPACT OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY REVIEW STRATEGY ON DETECTION OF CHOROIDAL NEOVASCULARIZATION.

Retina 2019 Feb 11. Epub 2019 Feb 11.

Vitreoretinal Service, Cleveland Clinic Foundation, Cole Eye Institute, Cleveland, Ohio.

Purpose: To compare optical coherence tomography angiography (OCTA) review strategies for optimizing choroidal neovascularization (CNV) detection.

Methods: Eyes with CNV in the differential diagnosis were imaged with the Avanti RTVue XR HD (Optovue, Fremont, CA). Three modalities of review for CNV presence were used in each case: a single report generated using automated segmentation within Avanti software; a continuous slab descent video OCTA export; and a manual segmentation approach using cross-sectional OCT with decorrelation signal overlay. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002443DOI Listing
February 2019

ACUTE MACULAR AND PERIPAPILLARY ANGIOGRAPHIC CHANGES WITH INTRAVITREAL INJECTIONS.

Retina 2019 Feb 11. Epub 2019 Feb 11.

Department of Ophthalmology, The New York Eye and Ear Infirmary of Mount Sinai, New York, New York.

Purpose: Intravitreal injections acutely and temporarily increase intraocular pressure (IOP), and this may have cumulative long-term effects including an increased risk for glaucoma surgery. This study was designed to measure retinal perfusion density changes on optical coherence tomography (OCT) angiography and OCT thickness alterations associated with acutely increased IOP after intravitreal injections.

Methods: Retrospective observational clinical study of 40 eyes (39 patients) with various retinopathies from October 2016 to June 2017 at a tertiary care retina clinic in NYC. Read More

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http://dx.doi.org/10.1097/IAE.0000000000002433DOI Listing
February 2019

Evaluation of Ocular Surface Disease in Patients With Glaucoma: Clinical Parameters, Self Report Assessment, and Keratograph Analysis.

J Glaucoma 2019 Feb 12. Epub 2019 Feb 12.

Glaucoma Services, Dr. Shroff's Charity Eye Hospital, Daryaganj, Delhi - 110 002, India.

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http://dx.doi.org/10.1097/IJG.0000000000001213DOI Listing
February 2019

Kahook Dual Blade (KDB) in Severe and Refractory Glaucoma.

J Glaucoma 2019 Feb 12. Epub 2019 Feb 12.

Sita lakshmi glaucoma center, Anand eye institute, 7-147/1, Nagendra Nagar, Habsiguda, Hyderabad, Telangana, India.

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http://dx.doi.org/10.1097/IJG.0000000000001210DOI Listing
February 2019

An eye for an eye? A meta-analysis of negative reciprocity in organizations.

J Appl Psychol 2019 Feb 14. Epub 2019 Feb 14.

Department of Management, Sam and Irene Black School of Business, Pennsylvania State University-Erie.

Most models of negative workplace behaviors (NWB) are individual in nature, focusing on individual attitudes (e.g., satisfaction) and general workplace perceptions (e. Read More

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http://dx.doi.org/10.1037/apl0000396DOI Listing
February 2019

The quantitative measuring method of meibomian gland vagueness and diagnostic efficacy of meibomian gland index combination.

Authors:
Yue Yin Lan Gong

Acta Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Department of Ophthalmology and Vision Science, The Eye & ENT Hospital of Fudan University, Shanghai, China.

Purpose: To propose and to evaluate a quantitative measuring method of meibomian gland (MG) vagueness.

Methods: A total of 47 patients (32 female and 15 male, 39.21 ± 11. Read More

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http://dx.doi.org/10.1111/aos.14052DOI Listing
February 2019

Ultrahigh-resolution anterior segment optical coherence tomography for analysis of corneal microarchitecture during wound healing.

Acta Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.

Purpose: To employ ultrahigh-resolution (UHR) optical coherence tomography (OCT) for investigation of the early wound healing process in corneal epithelium.

Methods: A custom-built UHR-OCT system assessed epithelial healing in human keratoconic cornea after epi-off crosslinking (CXL) procedure and a wound healing model in rabbits with iatrogenic corneal injury. 3D OCT data sets enhanced obtaining epithelial thickness maps and evaluation of reepithelization stage. Read More

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http://dx.doi.org/10.1111/aos.14053DOI Listing
February 2019

Real-world efficacy and safety of dividing aflibercept into three syringes in the treatment of wet age-related macular degeneration.

Acta Ophthalmol 2019 Feb 14. Epub 2019 Feb 14.

Tays Eye Centre, Tampere University Hospital, Tampere, Finland.

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http://dx.doi.org/10.1111/aos.14051DOI Listing
February 2019

Genetics of anophthalmia and microphthalmia. Part 1: Non-syndromic anophthalmia/microphthalmia.

Hum Genet 2019 Feb 14. Epub 2019 Feb 14.

Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK.

Eye formation is the result of coordinated induction and differentiation processes during embryogenesis. Disruption of any one of these events has the potential to cause ocular growth and structural defects, such as anophthalmia and microphthalmia (A/M). A/M can be isolated or occur with systemic anomalies, when they may form part of a recognizable syndrome. Read More

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http://dx.doi.org/10.1007/s00439-019-01977-yDOI Listing
February 2019

Differences in the Clinical and Laboratory Features of Imported Onchocerciasis in Endemic Individuals and Temporary Residents.

Am J Trop Med Hyg 2019 Feb 11. Epub 2019 Feb 11.

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.

Many parasitic infections have different presenting features in endemic individuals (ENDs) and immunologically naive temporary residents (TRs). Temporary residents with loiasis often display acute symptoms and hypereosinophilia, in contrast to a parasite-induced subclinical state in chronically infected ENDs. Few studies have examined differences in ENDs and TRs infected with the related filarial parasite . Read More

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http://dx.doi.org/10.4269/ajtmh.18-0757DOI Listing
February 2019

Paramedic and Emergency Medical Technician Reflections on the Ongoing Impact of the 9/11 Terrorist Attacks.

Prehosp Disaster Med 2019 Feb;34(1):56-61

3Harvard Humanitarian Initiative,Harvard University and Harvard T.C. Chan School of Public Health,Cambridge,MassachusettsUSA.

IntroductionIn the years following the September 11, 2001 terrorist attacks in New York City (New York USA), otherwise known as 9/11, first responders began experiencing a range of health and psychosocial impacts. Publications documenting these largely focus on firefighters. This research explores paramedic and emergency medical technician (EMT) reflections on the long-term impact of responding to the 9/11 terrorist attacks. Read More

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http://dx.doi.org/10.1017/S1049023X18001255DOI Listing
February 2019

Evaluation of the retinal nerve fiber layer and ganglion cell complex thicknesses in patients with exfoliation syndrome

Turk J Med Sci 2019 Feb 11;49(1):272-278. Epub 2019 Feb 11.

Background/aim: This study aimed to evaluate retinal nerve fiber layer (RNFL) and ganglion cell complex (GCC) thicknesses using spectral domain optical coherence tomography (SD-OCT) in both unilateral and bilateral exfoliation syndrome (XFS) patients

Materials And Methods: Twenty-four patients with unilateral XFS, 20 patients with bilateral XFS, and 23 healthy subjects were enrolled in this study. Eyes with XFS were compared with both fellow eyes and age-matched control subject eyes in terms of mean and segmental RNFL thickness and minimum, mean, and segmental GCC thickness.

Results: In the bilateral XFS group, minimum GCC of the right eye (75. Read More

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http://dx.doi.org/10.3906/sag-1803-27DOI Listing
February 2019

Parts-based representations of perceived face movements in the superior temporal sulcus.

Hum Brain Mapp 2019 Feb 13. Epub 2019 Feb 13.

Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, Massachusetts.

Facial motion is a primary source of social information about other humans. Prior fMRI studies have identified regions of the superior temporal sulcus (STS) that respond specifically to perceived face movements (termed fSTS), but little is known about the nature of motion representations in these regions. Here we use fMRI and multivoxel pattern analysis to characterize the representational content of the fSTS. Read More

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http://doi.wiley.com/10.1002/hbm.24540
Publisher Site
http://dx.doi.org/10.1002/hbm.24540DOI Listing
February 2019
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A case-control-family study of idiopathic rapid eye movement sleep behavior disorder.

Ann Neurol 2019 Feb 13. Epub 2019 Feb 13.

Sleep Assessment Unit, Department of Psychiatry, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, SAR, China.

Background: To determine the familial aggregation of idiopathic rapid eye movement sleep behavior disorder (iRBD), neurodegenerative diseases, and related biomarkers.

Methods: A total of 404 and 387 first-degree relatives of 102 patients with iRBD and 89 controls were recruited, respectively. Among them, 204 and 208 relatives of patients and controls underwent face-to-face clinical assessment, while 97 and 75 relatives underwent further video-polysomnographic assessment, respectively. Read More

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http://dx.doi.org/10.1002/ana.25435DOI Listing
February 2019

In response to letter to the editor regarding: "Patient-reported versus physiologic swallowing outcomes in patients with head and neck cancer after chemoradiation".

Laryngoscope 2019 Feb 13. Epub 2019 Feb 13.

Department of Speech, Language, and Swallowing Disorders, Massachusetts General Hospital, Boston, Massachusetts, U.S.A.

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http://dx.doi.org/10.1002/lary.27857DOI Listing
February 2019

Neurometabolic Hereditary Diseases of Adults.

Authors:
Georg F Hoffmann

J Inherit Metab Dis 2019 Feb 13. Epub 2019 Feb 13.

University Children's Hospital, Ruprecht-Karls-University Heidelberg, Heidelberg, Germany.

Springer International Publishing AG 2018, ISBN 978-3-319-76148-0, ISBN 978-3-319-76148-0 (ebook) Growing up is a fascinating journey. The book "Neurometabolic Hereditary Diseases of Adults" designed and edited by Dr. Allessandro P. Read More

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http://dx.doi.org/10.1002/jimd.12074DOI Listing
February 2019

Traumatic eye injury from an exploding aerosol can.

Med J Aust 2019 Feb 13. Epub 2019 Feb 13.

Royal Victorian Eye and Ear Hospital, Melbourne, VIC.

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http://dx.doi.org/10.5694/mja2.50009DOI Listing
February 2019

The clinical presentation of cobalamin-related disorders: From acquired deficiencies to inborn errors of absorption and intracellular pathways.

J Inherit Metab Dis 2018 Dec 27. Epub 2018 Dec 27.

Division of Metabolism and Children's Research Center, University Children's Hospital Zürich, Zürich, Switzerland.

This review gives an overview of clinical characteristics, treatment and outcome of nutritional and acquired cobalamin (Cbl; synonym: vitamin B12) deficiencies, inborn errors of Cbl absorption and intracellular trafficking, as well as methylenetetrahydrofolate dehydrogenase (MTHFD1) and methylene tetrahydrofolate reductase (MTHFR) deficiencies, which impair Cbl-dependent remethylation. Acquired and inborn Cbl-related disorders and MTHFR deficiency cause multisystem, often severe disease. Failure to thrive, neurocognitive or psychiatric symptoms, eye disease, bone marrow alterations, microangiopathy and thromboembolic events are characteristic. Read More

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http://dx.doi.org/10.1002/jimd.12012DOI Listing
December 2018

Risk Behaviors Associated with Alcohol Consumption Predict Future Severe Liver Disease.

Dig Dis Sci 2019 Feb 14. Epub 2019 Feb 14.

Stress Research Institute, Stockholm University, Stockholm, Sweden.

Background: Excess consumption of alcohol can lead to cirrhosis, but it is unclear whether the type of alcohol and pattern of consumption affects this risk.

Aims: We aimed to investigate whether type and pattern of alcohol consumption early in life could predict development of severe liver disease.

Methods: We examined 43,242 adolescent men conscribed to military service in Sweden in 1970. Read More

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http://dx.doi.org/10.1007/s10620-019-05509-6DOI Listing
February 2019
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