8,521 results match your criteria Eye[Journal]


Long-term natural history of idiopathic epiretinal membranes with good visual acuity.

Eye (Lond) 2019 Apr 19. Epub 2019 Apr 19.

Department of Ophthalmology & Vision Sciences, University of California, Davis, Sacramento, CA, USA.

Background/objectives: To evaluate the long-term progression of idiopathic epiretinal membranes (iERMs) with good baseline visual acuity, and to identify predictors of visual decline.

Design: Retrospective case series SUBJECTS METHODS: We reviewed records of 145 eyes with iERM and best-corrected visual acuity (BCVA) of 20/40 or greater at presentation, including BCVA, lens status, and central macular thickness (CMT) at yearly visits; as well as anatomic biomarkers including vitreomacular adhesion, pseudohole, lamellar hole, intraretinal cysts, disorganization of the inner retinal layers (DRIL), and disruption of outer retinal layers. Linear mixed effects and mixed-effects Cox proportional hazards models were used to identify clinical and anatomic predictors of vision change and time to surgery. Read More

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http://www.nature.com/articles/s41433-019-0397-z
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http://dx.doi.org/10.1038/s41433-019-0397-zDOI Listing
April 2019
1 Read

Tyrosinase (TYR) gene sequencing and literature review reveals recurrent mutations and multiple population founder gene mutations as causative of oculocutaneous albinism (OCA) in Pakistani families.

Eye (Lond) 2019 Apr 17. Epub 2019 Apr 17.

Department of Human Genetics and Molecular Biology, University of Health Sciences (UHS), Lahore, Pakistan.

Purpose: To investigate eight previously unreported Pakistani families with genetically undefined OCA for mutations in TYR.

Methods: Sanger sequencing of TYR has been performed in eight families with OCA phenotype. Mutation analysis was performed to establish the pathogenic role of novel mutation. Read More

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http://dx.doi.org/10.1038/s41433-019-0436-9DOI Listing

Visual Function Questionnaire as an outcome measure for homonymous hemianopia: subscales and supplementary questions, analysis from the VISION trial.

Eye (Lond) 2019 Apr 17. Epub 2019 Apr 17.

Division of Health and Social Care, King's College, London, WC2B 5RL, UK.

Background: We conduct supplementary analyses of the NEI VFQ-25 data to evaluate where changes occurred within subscales of the NEI VFQ-25 leading to change in the composite scores between the three treatment arms, and evaluate the NEI VFQ-25 with and without the Neuro 10 supplement.

Methods: A prospective, multicentre, parallel, single-blind, three-arm RCT of fourteen UK acute stroke units was conducted. Stroke survivors with homonymous hemianopia were recruited. Read More

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http://dx.doi.org/10.1038/s41433-019-0441-zDOI Listing
April 2019
1 Read

A hidden footprint: embryological origins of age related macular degeneration.

Eye (Lond) 2019 Apr 17. Epub 2019 Apr 17.

Institute of Ophthalmology, University College London, London, UK.

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http://www.nature.com/articles/s41433-019-0444-9
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http://dx.doi.org/10.1038/s41433-019-0444-9DOI Listing
April 2019
1 Read

Comparison between patient-reported outcomes after enucleation and proton beam radiotherapy for uveal melanomas: a 2-year cohort study.

Eye (Lond) 2019 Apr 15. Epub 2019 Apr 15.

Liverpool Ocular Oncology Centre, Royal Liverpool and Broadgreen University Hospital, NHS Trust, Prescot St, Liverpool, L7 8XP, UK.

Background: Uveal melanomas affect 2-8 per million Europeans each year. Approximately 35%, are treated by enucleation. Proton beam radiotherapy (PBR) can be an eye-conserving alternative to enucleation for patients who wish to retain the eye. Read More

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http://www.nature.com/articles/s41433-019-0440-0
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http://dx.doi.org/10.1038/s41433-019-0440-0DOI Listing
April 2019
1 Read

National incidence of eyelid cancer in Ireland (2005-2015).

Eye (Lond) 2019 Apr 11. Epub 2019 Apr 11.

Sligo University Hospital, Sligo, Ireland.

Aims: We report on the incidence of cutaneous eyelid tumours in Ireland over the 11-year-period from 2005 to 2015, we identify associations between demographic factors and cutaneous eyelid tumour risk.

Methods: Skin cancers, including basal cell carcinoma (BCC), squamous cell carcinoma (SCC), melanoma, and other cancers, located on the eyelid or canthus according to ICD-10 coding, as registered by the National Cancer Registry of Ireland (NCRI), were captured from the period 2005 to 2015. Age standardised rates (ASR) were calculated according to the European Standard Population (2013). Read More

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http://www.nature.com/articles/s41433-019-0437-8
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http://dx.doi.org/10.1038/s41433-019-0437-8DOI Listing
April 2019
5 Reads

Two-stage aqueous drainage tube implant with pericardial graft patch.

Eye (Lond) 2019 Apr 11. Epub 2019 Apr 11.

Western Eye Hospital, Imperial Healthcare Trust, London, UK.

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http://www.nature.com/articles/s41433-019-0433-z
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http://dx.doi.org/10.1038/s41433-019-0433-zDOI Listing
April 2019
4 Reads

Risk of aphakic glaucoma after pars plana-lensectomy with and without removal of the peripheral lens capsule.

Eye (Lond) 2019 Apr 10. Epub 2019 Apr 10.

Eye Center, Medical Center, Medical Faculty, University of Freiburg, Freiburg, Germany.

Background: The etiology of aphakic glaucoma is unclear. It has been suggested that remaining lens epithelium releases cytokines transducing trabecular meshwork cells. Therefore, we compared two cohorts of children undergoing lensectomy. Read More

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http://dx.doi.org/10.1038/s41433-019-0435-xDOI Listing

Test performance of optical coherence tomography angiography in detecting retinal diseases: a systematic review and meta-analysis.

Eye (Lond) 2019 Apr 10. Epub 2019 Apr 10.

Eye Clinic, Cantonal Hospital of Lucerne, Lucerne, Switzerland.

Objective: To investigate the diagnostic accuracy of optical coherence tomography angiography (OCTA) in detecting vascular characteristics of chorio-retinal disease.

Methods: Evidence acquisition: We searched Web of Science, Scopus, and Medline by the citation of references and complemented these electronic searches by checking the list of references of included and review articles. Screening, selection, assessment, and extraction was performed in parallel by two authors. Read More

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http://dx.doi.org/10.1038/s41433-019-0421-3DOI Listing

Optical coherence tomography angiography of types 1 and 2 choroidal neovascularization in age-related macular degeneration during anti-VEGF therapy: evaluation of a new quantitative method.

Eye (Lond) 2019 Apr 10. Epub 2019 Apr 10.

Department of Ophthalmology, St. Franziskus Hospital, Münster, Germany.

Purpose: The aim of this pilot study was to test whether mathematical parameters of the vascular morphology of choroidal neovascularization (CNV) can be used as biomarkers and to investigate how these parameters change during anti-vascular endothelial growth factor (VEGF) therapy.

Methods: Treatment-naive CNV in exudative age-related macular degeneration (AMD) was diagnosed in 28 patients. OCT-angiography (OCT-A) (Avanti/FA Optovue) performed before and after anti-VEGF therapy. Read More

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http://dx.doi.org/10.1038/s41433-019-0429-8DOI Listing

Correlation between structural progression in glaucoma and obstructive sleep apnea.

Eye (Lond) 2019 Apr 10. Epub 2019 Apr 10.

Department of Ophthalmology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background/objectives: To investigate the correlation between obstructive sleep apnea (OSA) severity and the structural and functional progression in patients with glaucoma.

Subjects/methods: This retrospective comparative cohort study included subjects from the polysomnography database in Chang Gung Memorial Hospital between June 1, 2009, and June 1, 2017, by identifying patients who had received diagnoses of primary open-angle glaucoma (POAG), normal-tension glaucoma (NTG), or glaucoma suspect. Patients with follow-up time of <3 years and/or <3 consecutive reliable optical coherence tomography (OCT) or visual field (VF) tests were excluded. Read More

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http://dx.doi.org/10.1038/s41433-019-0430-2DOI Listing
April 2019
3 Reads

Biotherapeutics and immunogenicity: ophthalmic perspective.

Eye (Lond) 2019 Apr 9. Epub 2019 Apr 9.

Division of Ophthalmology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

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http://dx.doi.org/10.1038/s41433-019-0434-yDOI Listing

Children's Hospital of Philadelphia Score to predict severe retinopathy in Indian preterm infants.

Eye (Lond) 2019 Apr 8. Epub 2019 Apr 8.

National Institute of Immunohaematology, Indian Council of Medical Research, Mumbai, India.

Background: Retinopathy of Prematurity (ROP) screenings are expensive and entail heavy workload. Predictive models using postnatal weight gain reduces the number of ophthalmological examinations. The objective was to validate Children's Hospital of Philadelphia (CHOP) score to predict severe ROP in resource limited settings. Read More

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http://dx.doi.org/10.1038/s41433-019-0431-1DOI Listing

Foveal and parafoveal choroidal thickness pattern measuring by swept source optical coherence tomography.

Eye (Lond) 2019 Apr 8. Epub 2019 Apr 8.

Vitreoretinal Research Unit, Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Objective: To evaluate the choroidal thickness (CT) in foveal and parafoveal regions in Thai adults using swept-source optical coherence tomography (SS-OCT).

Methods: We enrolled healthy volunteers ≥18 years of age from King Chulalongkorn Memorial Hospital, Thailand, during September 2015 to March 2016. Optical coherence tomography (OCT) of the macula was performed, and subfoveal CT was measured manually using a line scan. Read More

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http://dx.doi.org/10.1038/s41433-019-0404-4DOI Listing
April 2019
1 Read

The practice patterns in the management of sebaceous carcinoma of the eyelid in the Asia Pacific region.

Eye (Lond) 2019 Apr 5. Epub 2019 Apr 5.

Department of Ophthalmology, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong SAR, China.

Purpose: To determine the practice patterns of ophthalmic plastic surgeons regarding the management of eyelid sebaceous carcinoma (SC).

Methods: An electronic survey was distributed to oculoplastic surgical colleagues in the Asia Pacific region requesting clinical information and treatment approaches to SC.

Results: The responses from 192 respondents from the Asia Pacific region was included and analyzed in this study. Read More

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http://dx.doi.org/10.1038/s41433-019-0432-0DOI Listing
April 2019
1 Read

Long-term outcomes of patients with myopic traction maculopathy after phacoemulsification for incident cataract.

Eye (Lond) 2019 Apr 5. Epub 2019 Apr 5.

Department of Ophthalmology, Eye & ENT Hospital of Fudan University, 83 Fenyang Road, 200031, Shanghai, China.

Purpose: To evaluate the long-term effect of cataract surgery on highly myopic patients with myopic traction maculopathy (MTM) and the risk factors associated with MTM progression.

Methods: Highly myopic patients with cataract and MTM were included. Phacoemulsification surgery was performed on patients who had vision loss below 20/63 and were willing to operation. Read More

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http://dx.doi.org/10.1038/s41433-019-0416-0DOI Listing
April 2019
3 Reads

Diagnosis and surgical management of orbital sparganosis.

Eye (Lond) 2019 Apr 3. Epub 2019 Apr 3.

The State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, 510060, Guangzhou, People's Republic of China.

Purpose/background: Orbital sparganosis represents an extremely rare condition with only a few cases being reported in literature. Here we describe cases of orbital sparganosis, including their etiology, clinical findings, and surgical outcomes.

Patients And Methods: A retrospective review was performed on patients with orbital sparganosis, who were treated at Zhongshan Ophthalmic Center, of Sun Yat-sen University, China between 2000 and 2012. Read More

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http://dx.doi.org/10.1038/s41433-019-0427-xDOI Listing
April 2019
3 Reads

Direct eyelid defect closure: a prospective study of functional and aesthetic outcomes.

Eye (Lond) 2019 Apr 3. Epub 2019 Apr 3.

Royal Eye Infirmary, Derriford Hospital, Derriford Rd., Plymouth, PL6 8DH, UK.

Background/objectives: Direct closure (DC) of eyelid defects has been retrospectively shown to give excellent outcomes. We present prospective outcome data as further evidence to promote its wider use.

Subjects And Methods: A consecutive, unselected, series of patients undergoing eyelid tumour resection was studied prospectively. Read More

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http://dx.doi.org/10.1038/s41433-019-0414-2DOI Listing
April 2019
1 Read

Intra-lenticular lens aspiration in paediatric cases with anterior dislocation of lens.

Eye (Lond) 2019 Apr 3. Epub 2019 Apr 3.

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

Purpose: To assess the outcomes of intra-lenticular lens aspiration (ILLA) in paediatric cases with anterior dislocation of lens.

Methods: A retrospective review of medical records of cases with anterior dislocation of the lens in children (age < 16 years) that underwent ILLA between June 2017 and May 2018 was performed. Corrected distance visual acuity (CDVA), intraocular pressure (IOP), and anterior segment findings were noted at presentation and follow-up. Read More

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http://www.nature.com/articles/s41433-019-0426-y
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http://dx.doi.org/10.1038/s41433-019-0426-yDOI Listing
April 2019
4 Reads

Long-term outcomes of bilateral lateral rectus recession versus unilateral lateral rectus recession-medial rectus plication in children with basic type intermittent exotropia.

Eye (Lond) 2019 Apr 3. Epub 2019 Apr 3.

Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Purpose: To compare the long-term surgical outcomes between bilateral lateral rectus recession (BLR) and unilateral lateral rectus recession-medial rectus plication (RP) in intermittent exotropia.

Methods: Children who underwent BLR or RP for basic type intermittent exotropia between 2015 and 2016 with a minimum follow-up period of 2 years were retrospectively reviewed. Surgical outcomes were classified based on postoperative angle of deviation as follows: success (esodeviation ≤ 5 prism diopters [PD] to exodeviation ≤ 10 PD), and failure (overcorrection [esodeviation > 5 PD] and undercorrection or recurrence [exodeviation > 10 PD]). Read More

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http://dx.doi.org/10.1038/s41433-019-0422-2DOI Listing
April 2019
2 Reads

Treatment of presumed trematode-induced granulomatous anterior uveitis among children in rural areas of Egypt.

Eye (Lond) 2019 Apr 3. Epub 2019 Apr 3.

Mansoura Ophthalmic center, Mansoura University, Mansoura, Egypt.

Purpose: The purpose of this study is to evaluate the efficacy of systemic antiparasitic medications alone or in combination with surgical aspiration in management of presumed trematode-induced anterior uveitis in children.

Patients And Methods: Prospective case series. Children who presented with anterior chamber (AC) granuloma were included in the study. Read More

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http://dx.doi.org/10.1038/s41433-019-0428-9DOI Listing
April 2019
5 Reads

The effect of single periocular injection of methylprednisolone and drainage of suprachoroidal fluid in the treatment of rhegmatogenous retinal detachment combined with choroidal detachment.

Eye (Lond) 2019 Apr 2. Epub 2019 Apr 2.

The Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China.

Purpose: In this study we compared the anatomic and functional outcomes of two steroid treatments on rhegmatogenous retinal detachment (RRD) combined with choroidal detachment (CD), namely treatment with oral prednisolone (1 mg/kg daily) for 3-7 days before vitrectomy or a single periocular injection of methylprednisolone (40 mg) 1-3 days before vitrectomy. We also analyzed the outcomes of the eyes with subsided CD and the eyes with persistent CD that underwent drainage of suprachoroidal fluids during the vitrectomy.

Methods: This was a prospective randomized study. Read More

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http://dx.doi.org/10.1038/s41433-019-0420-4DOI Listing

Cochrane Corner: Ocriplasmin-why isn't it being used more?

Eye (Lond) 2019 Apr 2. Epub 2019 Apr 2.

Sunderland Eye Infirmary, Queen Alexandra Road, Sunderland, SR2 9HP, UK.

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http://dx.doi.org/10.1038/s41433-019-0407-1DOI Listing
April 2019
1 Read

How stressful is cataract surgery for consultants and ophthalmic trainees? Phacoemulsification is a stressful experience for young consultants.

Eye (Lond) 2019 Apr 1. Epub 2019 Apr 1.

Department of Ophthalmology, Singleton Hospital, Sketty Lane, Swansea, SA2 8QA, UK.

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http://dx.doi.org/10.1038/s41433-019-0423-1DOI Listing
April 2019
1 Read

Bilateral advanced (group D or E) intraocular retinoblastoma: outcomes in 72 Asian Indian patients.

Eye (Lond) 2019 Apr 1. Epub 2019 Apr 1.

Operation Eyesight Universal Institute for Eye Cancer, Hyderabad, India.

Purpose: To study the clinical presentation, treatment, and outcomes of patients with bilateral advanced intraocular retinoblastoma.

Methods: Retrospective case series of 72 patients.

Results: The mean age at presentation was 19 months. Read More

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http://dx.doi.org/10.1038/s41433-019-0409-zDOI Listing

Myopic traction maculopathy biomarkers on optical coherence tomography angiography-An overlooked mechanism of visual acuity correction in myopic eyes.

Eye (Lond) 2019 Apr 1. Epub 2019 Apr 1.

Department of Ophthalmology, National Taiwan University Hospital, College of Medicine, National Taiwan University, No. 7, Chung-Shan S. Rd, Taipei City, 10002, Taiwan.

Background/objectives: Myopic traction maculopathy of the retinoschisis type is a unique entity that has been frequently overlooked in refraction correction in daily practice in myopic eyes. The objective of this study was to describe the imaging characteristics of myopic traction maculopathy (MTM) seen on optical coherence tomography angiography (OCTA) and to detect biomarkers of the associated functional changes.

Subjects/methods: We performed OCTA on eyes with MTM and retinoschisis (RS group; n = 27) and highly myopic eyes without MTM (control group; n = 27). Read More

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http://dx.doi.org/10.1038/s41433-019-0424-0DOI Listing
April 2019
1 Read

Surgical and sensory outcomes in patients with intermittent exotropia according to preoperative refractive error.

Eye (Lond) 2019 Apr 1. Epub 2019 Apr 1.

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Background/objectives: To analyze the surgical and sensory outcomes of intermittent exotropia according to refractive errors and the factors associated with surgical success.

Subjects/methods: A total of 326 children were divided into three groups according to preoperative refractive error; hyperopic eyes with SE ≥+2D (hyperopic group), eyes with SE between -1D and +2D (emmetropic group), and myopic eyes with SE ≤-1D (myopic group). The surgical outcomes and the sensory outcomes measured by near and distant stereoacuity were compared among the three groups. Read More

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http://dx.doi.org/10.1038/s41433-019-0419-xDOI Listing

Evaluation of photoreceptor outer segment length in hydroxychloroquine users.

Eye (Lond) 2019 Apr 1. Epub 2019 Apr 1.

Department of Ophthalmology, University of Health Sciences, Okmeydani Training and Research Hospital, Istanbul, Turkey.

Objective: This study aims to evaluate the photoreceptor outer segment (PROS) length in patients who use hydroxychloroquine (HCQ) prior to the development of retinopathy.

Methods: In this prospective, single-centre, comparative study, 44 patients using HCQ for ≥5 years, 30 patients using HCQ <5 years, and 45 age- and sex-matched healthy controls were enrolled. The participants underwent a detailed ophthalmologic examination, spectral-domain optical coherence tomography (SD-OCT) imaging, and 10-2 automated visual field testing. Read More

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http://dx.doi.org/10.1038/s41433-019-0425-zDOI Listing
April 2019
3 Reads

Membrane patterns in eyes with choroidal neovascularization on optical coherence tomography angiography.

Eye (Lond) 2019 Apr 1. Epub 2019 Apr 1.

Istanbul Retina Institute, Istanbul, Turkey.

Background: To evaluate morphologic patterns of choroidal neovascular membranes using optical coherence tomography angiography (OCTA) in patients with treatment-naive, continuously treated, and previously treated exudative age-related macular degeneration (AMD).

Subjects: We assessed retrospectively 184 eyes of 153 patients diagnosed with type 1, type 2, and mixed-type neovascularization associated with AMD. The type of neovascularization and clinical activity were assessed by clinical examination and spectral domain optical coherence tomography (SD-OCT). Read More

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http://dx.doi.org/10.1038/s41433-019-0415-1DOI Listing

Action on neovascular age-related macular degeneration (nAMD): recommendations for management and service provision in the UK hospital eye service.

Eye (Lond) 2019 Mar;33(Suppl 1):1-21

The Action on nAMD Group, Birmingham, UK.

This report by a group of UK retina specialists and health professionals considers best practice recommendations for the management of sight-threatening neovascular age-related macular degeneration (nAMD), based on collective experience and expertise in routine clinical practice. The authors provide an update for ophthalmologists, allied healthcare professionals and commissioners on practice principles for optimal patient care and service provision standards. Refinement of care pathways for nAMD has improved access to intravitreal anti-vascular endothelial growth factor therapy but there are still variations in care and reported outcomes between clinic centres. Read More

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http://dx.doi.org/10.1038/s41433-018-0300-3DOI Listing
March 2019
3 Reads

Peripapillary retinal nerve fiber layer and ganglion cell complex degeneration in Egyptian patients with bipolar disorder.

Eye (Lond) 2019 Mar 29. Epub 2019 Mar 29.

Psychiatry Department, Faculty of Medicine, Cairo University, Giza, Egypt.

Purpose: To determine if changes in OCT parameters including peripapillary RNFL thickness and GCC thickness in Egyptian patients with bipolar disorder exist, and to correlate them with disease severity and clinical characteristics.

Methods: A case-control study conducted on 40 patients with bipolar disorder were compared to 40 matched healthy controls. Both patients and controls were subjected to ophthalmic examination including: BCVA, slit-lamp examination, fundus examination, and OCT imaging. Read More

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http://dx.doi.org/10.1038/s41433-019-0403-5DOI Listing
March 2019
1 Read

Optical coherence tomography evidence of macular ganglion cell-inner plexiform layer thinning in eyes with subretinal drusenoid deposits.

Eye (Lond) 2019 Mar 29. Epub 2019 Mar 29.

Ophthalmology Unit, Department of Sense Organs, Azienda Policlinico Umberto I, "Sapienza "University of Rome, Rome, Italy.

Background/objectives: The purpose of this study was to evaluate macular ganglion cell layer-inner plexiform layer (GCL-IPL) and choroidal thickness in early age-related macular degeneration (AMD) in eyes with subretinal drusenoid deposits (SDD).

Subjects/methods: Comprehensive ophthalmological examination was performed. Near infrared reflectance and raster images using enhanced depth imaging were acquired with spectral domain optical coherence tomography. Read More

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http://dx.doi.org/10.1038/s41433-019-0405-3DOI Listing
March 2019
1 Read

The invisible ophthalmologist.

Eye (Lond) 2019 Mar 29. Epub 2019 Mar 29.

Professional Standards Royal College of Ophthalmologists, London, UK.

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http://dx.doi.org/10.1038/s41433-019-0411-5DOI Listing
March 2019
1 Read

SAS Ophthalmologist: my positive career choice.

Authors:
Bronwen Attrup

Eye (Lond) 2019 Mar 29. Epub 2019 Mar 29.

United Lincolnshire Hospitals NHS Trust, Lincolnshire, UK.

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http://dx.doi.org/10.1038/s41433-019-0410-6DOI Listing

Digital photo-editing in preoperative counselling for cosmetic corneal tattooing.

Eye (Lond) 2019 Mar 28. Epub 2019 Mar 28.

Moorfields Eye Hospital, 162 City Road, London, EC1V 2PD, UK.

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http://dx.doi.org/10.1038/s41433-019-0412-4DOI Listing
March 2019
1 Read

Correction: Differences in eye movement range based on age and gaze direction.

Eye (Lond) 2019 Mar 28. Epub 2019 Mar 28.

Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Korea.

Since the online publication of the above article, the authors have noted an error with the funding. The authors apologize for any convenience caused by this error.The correct funding is:This work was supported by the research fund of Hanyang University (HY-201700000000487) and the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) (No. Read More

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http://dx.doi.org/10.1038/s41433-019-0413-3DOI Listing

A pilot study of fluorescence lifetime imaging ophthalmoscopy in preclinical Alzheimer's disease.

Eye (Lond) 2019 Mar 28. Epub 2019 Mar 28.

Doheny Eye Institute, University of California, Los Angeles, CA, USA.

Purpose: To investigate fluorescence lifetime imaging ophthalmoscopy (FLIO) findings in preclinical Alzheimer's disease (AD).

Methods: This prospective, observational study enrolled patients with early AD undergoing Alzheimer's biomarker analysis and matched controls. Alzheimer-associated parameters (β-amyloid [Aβ], total tau in cerebrospinal fluid [CSF], Mini-Mental Status Examination [MMSE], etc. Read More

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http://dx.doi.org/10.1038/s41433-019-0406-2DOI Listing
March 2019
1 Read

Intraocular application of Mitomycin C to prevent proliferative vitreoretinopathy in perforating and severe intraocular foreign body injuries.

Eye (Lond) 2019 Mar 27. Epub 2019 Mar 27.

Beirut Eye & ENT Specialist Hospital, Beirut, Lebanon.

Aim: To assess the long-term anatomical and functional outcomes in addition to complications of a new surgical technique of localized intraocular application of mitomycin C (MMC) to prevent proliferative vitreoretinopathy (PVR) in eyes with open globe trauma.

Methods: Prospective non-comparative interventional case series of 16 consecutive eyes with perforating and deep choroidal impact foreign body injuries presenting over a 2-year period. Patients underwent vitrectomy with intraocular application of MMC at the site of the chorioretinal injury and were followed-up for 1 year. Read More

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http://dx.doi.org/10.1038/s41433-019-0408-0DOI Listing

Near vision in individuals with Down syndrome: a vision screening study.

Eye (Lond) 2019 Mar 26. Epub 2019 Mar 26.

Brien Holden Institute of Optometry and Vision Sciences, Hyderabad Eye Research Foundation, L V Prasad Eye Institute, Hyderabad, India.

Objectives: Children with Down syndrome are known to have reduced focusing ability for near vision (hypoaccommodation). Through a vision screening study we investigated the correlation between hypoaccommodation and near visual acuity in individuals with Down syndrome.

Methods: A cross-sectional vision screening study was conducted on individuals with Down Syndrome. Read More

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http://dx.doi.org/10.1038/s41433-019-0402-6DOI Listing

Raised intra-ocular pressure in the setting of Coffin-Siris syndrome.

Eye (Lond) 2019 Mar 26. Epub 2019 Mar 26.

Department of Ophthalmology, Royal Victoria Hospital, Belfast Heath and Social Care Trust, Antrim, UK.

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http://dx.doi.org/10.1038/s41433-019-0399-xDOI Listing

Graded Anderson procedure for correcting abnormal head posture in infantile nystagmus.

Eye (Lond) 2019 Mar 25. Epub 2019 Mar 25.

Schneider Children's Medical Center of Israel, Petah Tikva, Israel.

Purpose: To describe the long-term results of Anderson procedure, which includes recession of the two extraocular yoke muscles responsible for eccentric eye position and abnormal head posture (AHP) in patients with infantile nystagmus.

Methods: Retrospective data collection of patients who underwent an Anderson procedure at a single medical center by one surgeon from 2008 to 2016. The main outcome measure was the elimination of AHP following surgery. Read More

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http://www.nature.com/articles/s41433-019-0400-8
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http://dx.doi.org/10.1038/s41433-019-0400-8DOI Listing
March 2019
7 Reads

Macular OCT-angiography parameters to predict the clinical stage of nonproliferative diabetic retinopathy: an exploratory analysis.

Eye (Lond) 2019 Mar 22. Epub 2019 Mar 22.

Department of Ophthalmology, Centro Hospitalar e Universitário de Coimbra - CHUC, E.P.E. Praceta Professor Mota Pinto, 3000-075, Coimbra, Portugal.

Background: To test whether a single or a composite set of macular vascular density parameters, evaluated with optical coherence tomography angiography (OCTA), are able to predict nonproliferative diabetic retinopathy (NPDR) staging according to the gold-standard ETDRS-grading scheme.

Methods: Prospectively defined, cross-sectional study in which macular structural and vascular parameters of diabetic eyes with nonproliferative DR (up to ETDRS Level 53) were evaluated with OCTA (Avanti RTVue-XR 100, Optovue Inc, Fremont, CA). Seven-field photographs of the fundus were taken for DR staging according to the ETDRS-grading scheme. Read More

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http://dx.doi.org/10.1038/s41433-019-0401-7DOI Listing

Handheld laser devices and laser-induced retinopathy (LIR) in children: an overview of the literature.

Eye (Lond) 2019 Mar 20. Epub 2019 Mar 20.

The Oxford Eye Hospital, John Radcliffe Hospital, Oxford, OX3 9DU, UK.

Handheld laser devices are easily available to purchase through the internet and unregulated marketplaces at a relatively low cost. They are particularly attractive to children as they are seen as 'high tech', brightly coloured, and known to be able to burn holes in objects such as balloons. There is a widespread lack of knowledge about the risks of viewing the beam emanating directly from handheld lasers, and particularly those with high-output powers. Read More

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http://dx.doi.org/10.1038/s41433-019-0395-1DOI Listing

Living with an artificial eye-the emotional and psychosocial impact.

Eye (Lond) 2019 Mar 19. Epub 2019 Mar 19.

Consultant Ophthalmologist, Princess Alexandra Eye Pavilion, Chalmers Street, Edinburgh, EH3 9HA, UK.

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http://www.nature.com/articles/s41433-019-0398-y
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http://dx.doi.org/10.1038/s41433-019-0398-yDOI Listing
March 2019
2 Reads

Assessment of the anterior segment of patients with primary congenital glaucoma using handheld optical coherence tomography.

Eye (Lond) 2019 Mar 18. Epub 2019 Mar 18.

Ophthalmology Group, University of Leicester, Leicester, UK.

Purpose: To investigate the potential of handheld optical coherence tomography (HH-OCT) in assessing the anterior segment of the eye in patients with primary congenital glaucoma.

Design: A prospective, case-controlled observational study.

Participants: Twenty-two patients with primary congenital glaucoma (PCG, 9 females and 13 males; mean age 4. Read More

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http://dx.doi.org/10.1038/s41433-019-0369-3DOI Listing

Safety and efficacy of intravitreal conbercept injection after vitrectomy for the treatment of proliferative diabetic retinopathy.

Eye (Lond) 2019 Mar 14. Epub 2019 Mar 14.

Tianjin Medical University Eye Hospital & Tianjin Medical University Eye Institute, Tianjin, China.

Background/objectives: The aim of this study was to evaluate the safety and efficacy of intravitreal conbercept (a recombinant fusion protein that primarily targets vascular endothelial growth factors) after vitrectomy for the management of proliferative diabetic retinopathy without tractional retinal detachment (TRD).

Subjects/methods: Fifty patients with non-clearing vitreous haemorrhage (VH) due to proliferative diabetic retinopathy without TRD were enroled. They were randomly divided into control and treatment groups (25 eyes to each group) after they provided informed consent. Read More

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http://dx.doi.org/10.1038/s41433-019-0396-0DOI Listing
March 2019
2 Reads
1.897 Impact Factor

Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP): telemedicine-based examination after laser photocoagulation for treatment-warranted retinopathy of prematurity.

Eye (Lond) 2019 Mar 12. Epub 2019 Mar 12.

Byers Eye Institute, Horngren Family Vitreoretinal Center, Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA, USA.

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http://dx.doi.org/10.1038/s41433-019-0392-4DOI Listing

The association between personality disorders/traits and violent eye trauma.

Eye (Lond) 2019 Mar 11. Epub 2019 Mar 11.

Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Aims: To determine the prevalence of various personality disorders in patients with open globe injuries caused by violent eye trauma.

Materials And Methods: One-hundred patients were divided equally to case and control groups. The case group was selected from admitted patients with open globe injury following a violent act. Read More

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http://dx.doi.org/10.1038/s41433-019-0394-2DOI Listing
March 2019
1 Read
1.897 Impact Factor

Socio-economic status and outcomes for patients with age-related macular degeneration.

Eye (Lond) 2019 Mar 11. Epub 2019 Mar 11.

Faculty of Medicine, University of Southampton, Southampton, UK.

Objectives: To explore disparities in severity of baseline disease, treatment completion, and treatment outcomes among patients with wet age-related macular degeneration (AMD) receiving anti-vascular endothelial growth factor therapy by socio-economic status (SES) and distance from home to hospital.

Study Design: Retrospective cohort study.

Methods: Data from clinic records of 756 wet AMD patients receiving treatment for wet AMD with aflibercept between May 2013 and Jan 2017 were obtained. Read More

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http://dx.doi.org/10.1038/s41433-019-0393-3DOI Listing