312,106 results match your criteria External Ear Malignant External Otitis


The adoption of sustainable practices: A supplier's perspective.

J Environ Manage 2018 Dec 3;232:692-701. Epub 2018 Dec 3.

Chinese Academy of Environmental Planning, Beijing, China.

Suppliers' adoption of sustainable practices plays a critical role for global companies to improve environmental performance. Based on the absorptive capacity theory, this study empirically explores how suppliers' knowledge bases and power relationships influence their adoption of sustainability practices. A longitudinal case study with eight suppliers has been conducted. Read More

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December 2018
4 Reads

Socioeconomic differences among resident, users and neighbour populations of a protected area in the Brazilian dry forest.

J Environ Manage 2018 Dec 3;232:607-614. Epub 2018 Dec 3.

Departamento de Biociências, Universidade Federal Rural do Semiárido, Av. Francisco Mota, 572, Mossoró, Rio Grande do Norte, Brazil. Electronic address:

Protected areas are an important strategy to safeguard biodiversity. However, if social development is not considered, biological conservation targets may not be achieved. In this empirical study, we assess the relationship between poverty and conservation goals in dry forests within a 62,000-ha Brazilian National Park (Caatinga biome). Read More

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December 2018
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Online behavior of people visiting a scientific website on epilepsy.

Epilepsy Behav 2018 Dec 3;90:79-83. Epub 2018 Dec 3.

'Sapienza' University of Rome, Human Neuroscience Department, Rome, Italy.

We investigated the online behavior of Internet users consulting the website of the Italian Chapter of the International League Against Epilepsy (Lega Italiana Contro l'Epilessia [LICE]). We obtained the visualization statistics of the LICE website using AWStats (https://awstats.sourceforge. Read More

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December 2018
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Long-term functional outcome after decompressive suboccipital craniectomy for space-occupying cerebellar infarction.

Clin Neurol Neurosurg 2018 Dec 1;176:47-52. Epub 2018 Dec 1.

Department of Neurosurgery, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.

Objectives: Suboccipital decompressive craniectomy (SDC) is considered the best treatment option in patients with space-occupying cerebellar infarction and clinical signs of deterioration. The primary purpose of this study was to evaluate long-term functional outcome in patients one year after SDC for space-occupying cerebellar infarction, and secondly, to determine factors associated with outcome.

Patients And Methods: All patients treated with SDC due to space-occupying cerebellar infarction between January 2009 and October 2015 were included in the study. Read More

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December 2018
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Time-dependently slow-released multiple-drug eluting external sheath for efficient long-term inhibition of saphenous vein graft failure.

J Control Release 2018 Dec 3. Epub 2018 Dec 3.

Department of Cardiac Surgery, First Affiliated Hospital, China Medical University, Shenyang, PR China. Electronic address:

Coronary artery bypass graft surgery (CABG) is an effective therapeutic method for coronary artery disease. Great saphenous vein is the predominant graft due to the accessibility, sufficient length and suitable size matching with coronary artery. However, saphenous vein graft failure (SVGF) always restrict the long-term success of CABG. Read More

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December 2018
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Structure and biomechanics of the antennal grooming mechanism in the southern green stink bug Nezara viridula.

J Insect Physiol 2018 Dec 3. Epub 2018 Dec 3.

Department of Functional Morphology and Biomechanics, Kiel University, Germany.

Insects devote a high amount of time to self-groom to remove foreign material, especially from their sensory appendages. Using various microscopy techniques and behavioural experiments on intact and ablated insects, the present study investigates the antennal grooming of the green stinkbug Nezara viridula, which represents a serious pest of different crops in most areas of the world. The antennal grooming behaviour encompass an action of scraping involving the tibial comb complex (tibial comb + fossula) of both forelegs, generally followed by the tibial comb complex grooming of one leg using the tarsal hairy pad of the opposite leg (rubbing). Read More

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December 2018

Electronic "Sniffer" Systems to Identify the Acute Respiratory Distress Syndrome: A Systematic Review.

Ann Am Thorac Soc 2018 Dec 6. Epub 2018 Dec 6.

University of Michigan, Internal Medicine, Ann Arbor, Michigan, United States ;

Background: The acute respiratory distress syndrome (ARDS) results in substantial mortality but remains underdiagnosed in clinical practice. Automated ARDS "sniffer" systems, tools that can automatically analyze electronic medical record data, have been developed to improve recognition of ARDS in clinical practice.

Objective: To perform a systematic review examining the evidence underlying automated sniffer systems for ARDS detection. Read More

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December 2018
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[Quantification of changes in the external morphology of the back by means of surface topography based on structured light in idiopathic scoliosis in adolescents after a year of treatment with orthopedic corse].

Acta Ortop Mex 2018 May-Jun;32(3):145-156

Servicio de Cirugía Ortopédica y Traumatología. Hospital Clínico Universitario de Valencia. Valencia, España.

Background: To quantify the morphological changes in the surface of the back of adolescents with idiopathic scoliosis as a result of treatment with braces and to correlate them with radiographic changes.

Material And Methods: An analytical, cohort, prospective study on a sample of 31 adolescents with idiopathic scoliosis. We divided them into two groups: eleven treated with braces and twenty without them. Read More

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December 2018

Comparison of brain magnetic resonance imaging between myotonic dystrophy type 1 and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

PLoS One 2018 6;13(12):e0208620. Epub 2018 Dec 6.

Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.

Background: Anterior temporal lobe hyperintensities detected by brain MRI are a recognized imaging hallmark of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Because similar findings may be present in patients with myotonic dystrophy type 1 (DM1), the brain MRI in these two diseases is often misinterpreted. We compared the MRI findings between the two entities to examine whether they display distinctive characteristics. Read More

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December 2018
4 Reads

Screening for osteoporosis: A systematic assessment of the quality and content of clinical practice guidelines, using the AGREE II instrument and the IOM Standards for Trustworthy Guidelines.

PLoS One 2018 6;13(12):e0208251. Epub 2018 Dec 6.

School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.

Background: Numerous clinical practice guidelines (CPGs) are published to guide management of osteoporosis. Little is known about their quality or how recommendations have changed over time.

Objective: To systematically assess the quality and content of the guidelines on screening for osteoporosis, using the Appraisal of Guidelines for Research and Evaluation (AGREE II) tool, and the Institute of Medicine (IOM) standards for trustworthy guidelines. Read More

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December 2018

The impact of a fine-scale population stratification on rare variant association test results.

PLoS One 2018 6;13(12):e0207677. Epub 2018 Dec 6.

INSERM, CNRS, UNIV Nantes, l'institut du thorax, Nantes, France.

Population stratification is a well-known confounding factor in both common and rare variant association analyses. Rare variants tend to be more geographically clustered than common variants, because of their more recent origin. However, it is not yet clear if population stratification at a very fine scale (neighboring administrative regions within a country) would lead to statistical bias in rare variant analyses. Read More

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December 2018

Effect of positive carbon-11-choline PET/CT results in the therapeutic management of prostate cancer biochemical relapse.

Nucl Med Commun 2019 Jan;40(1):79-85

Department of Nuclear Medicine, Marqués de Valdecilla University Hospital, Molecular Imaging Group (IDIVAL), University of Cantabria, Santander, Spain.

Objective: Carbon-11-(C)-choline PET/computed tomography (CT) has shown good results in re-staging of prostate cancer (PCa) with raised serum levels of prostate-specific antigen. Our aim was to evaluate the effect of positive C-choline PET/CT results in the therapeutic management of patients with PCa with biochemical relapse (BR) after curative intention treatment.

Patients And Methods: A total of 112 patients with PCa BR and positive C-choline PET/CT were retrospectively evaluated. Read More

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January 2019

Oligomerization of equilibrative nucleoside transporters: a novel regulatory and functional mechanism involving PKC and PP1.

FASEB J 2018 Dec 6:fj201800440RR. Epub 2018 Dec 6.

Department of Chemistry and Biology, Ryerson University, Toronto, Ontario, Canada.

Equilibrative nucleoside transporters (ENTs) translocate nucleosides and nucleobases across plasma membranes, as well as a variety of anti-cancer, -viral, and -parasite nucleoside analogs. They are also key members of the purinome complex and regulate the protective and anti-inflammatory effects of adenosine. Despite their important role, little is known about the mechanisms involved in their regulation. Read More

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December 2018
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[2, 2'-Bipyridin]-6(1H)-one, a Truly Cooperating Ligand in the Palladium-Mediated C-H Activation Step: Experimental Evidence in the Direct C-3 Arylation of Pyridine.

J Am Chem Soc 2018 Dec 6. Epub 2018 Dec 6.

The ligand [2, 2'-bipyridin]-6(1H)-one (bipy-6-OH) has a strong accelerating effect in the Pd-catalyzed direct arylation of pyridine or arenes. The isolation of relevant intermediates and the study of their decomposition unequivocally show that the deprotonated coordinated ligand acts as a base and assists the cleavage of the C-H bond. Mechanistic work indicates that the direct arylation of pyridine with this ligand occurs through a Pd(0)/Pd(II) cycle. Read More

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December 2018

Are Increased Masticatory Forces Risk for Primary 2nd Molars without Successors? A 3D FEA Study.

J Clin Pediatr Dent 2018 Dec 6. Epub 2018 Dec 6.

Objective: Persistent primary teeth with healthy crown-root structures and acceptable functional and esthetic properties may be preserved over a long-term period if needed. However, they may experience root resorption, ankylosis or infraocclusion especially in the second or third decades of life. Despite a lack of sufficient detailed data, increases in occlusal forces by age are known to cause destructive stresses on root surfaces and periodontal tissue. Read More

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December 2018

Robustly Superhydrophobic Conductive Textile for Efficient Electromagnetic Interference Shielding.

ACS Appl Mater Interfaces 2018 Dec 6. Epub 2018 Dec 6.

Superhydrophobic electromagnetic interference (EMI) shielding textile (EMIST) is of great significance to the safety and long-term service of all-weather outdoor equipment. However, it is still challenging to achieve long-term durability and stability under external mechanical deformations or other harsh service conditions. Herein, by designing and implementing silver nanowire (AgNW) networks and a superhydrophobic coating onto a commercial textile, we demonstrate a highly robust superhydrophobic EMIST. Read More

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December 2018

Force analysis of shoulder joint muscles in the early phase of brain stroke.

Acta Bioeng Biomech 2018 ;20(4):107-113

Department of Physical Medicine, Medical University of Lodz, Łódź, Poland.

Purpose: Upper limb impairment in the early phase of brain stroke is one of the key problems in rehabilitation. An estimation of muscle force can be a helpful factor for functional improvement after a stroke. The primary goals of this study were to determine the muscles with the lowest force in the affected (A) and non-affected (non-A) upper limb. Read More

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January 2018
2 Reads

Agency in dementia care: systematic review and meta-ethnography.

Int Psychogeriatr 2018 Dec 6:1-16. Epub 2018 Dec 6.

Division of Psychiatry and Applied Psychology, School of Medicine,University of Nottingham,Nottingham,UK.

ABSTRACTObjectives:Dementia often limits the agency of the person to such an extent that there is need for external support in making daily life decisions. This support is usually provided by family members who are sometimes legally empowered to engage in decision-making on behalf of the person for whom they care. However, such family carers receive little or no information on how to best provide support when there is a lack of capacity. Read More

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December 2018
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Individual optimal attentional strategy during implicit motor learning boosts frontoparietal neural processing efficiency: A functional near-infrared spectroscopy study.

Brain Behav 2018 Dec 5:e01183. Epub 2018 Dec 5.

Department of Neurosurgery, Jichi Medical University, Shimotsuke, Japan.

Introduction: Optimal focus of attention is a crucial factor for improving motor learning. Most previous studies have shown that directing attention to movement outcome (external focus; EF) is more effective than directing attention to body movement itself (internal focus; IF). However, our recent studies demonstrated that the optimal attentional strategy in healthy and clinical populations varies depending on individual motor imagery ability. Read More

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December 2018

P(III)-Chelation-Assisted Indole C7-Arylation, Olefination, Methylation, and Acylation with Carboxylic Acids/Anhydrides via Rhodium Catalysis.

Authors:
Zhuangzhi Shi

Angew Chem Int Ed Engl 2018 Dec 5. Epub 2018 Dec 5.

Nanjing University , School of Chemistry & Chemical Engineering, 163 Xianlin Avenue , 163, 210046, Nanjing, CHINA.

Rhodium-catalyzed C7-selective decarbonylative arylation, olefination and methylation of indoles with carboxylic acids or anhydrides via C-H and C-C bond activation have been developed. Furthermore, C7-acylation products can also be generated selectively at a lower reaction temperature in our system. The key to the high reactivity and regioselectivity of this transformation is the appropriate choice of an indole N-PtBu2 chelation-assisted group. Read More

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December 2018

Disruption of sex-specific doublesex exons results in male- and female-specific defects in the black cutworm, Agrotis ipsilon.

Pest Manag Sci 2018 Dec 6. Epub 2018 Dec 6.

Key Laboratory of Insect Developmental and Evolutionary Biology, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.

Background: Doublesex (dsx), the downstream gene in the insect sex determination pathway, is a key regulator of sexually dimorphic development and behavior across a variety of insects. Manipulating the expression of dsx could be a useful method in genetic control of insects. However, information on the sex-specific function of dsx in non-model insects is lacking. Read More

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December 2018
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Efficacy of external cold and a vibrating device in reducing discomfort of dental injections in children: A split mouth randomised crossover study.

Eur Arch Paediatr Dent 2018 Dec 5. Epub 2018 Dec 5.

Department of Paediatric Dentistry, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Aim: To study the discomfort and fear associated with maxillary infiltration injections when using a combination of external cold and a commercially available vibrating device.

Methodology: A total of 60 children aged 7 years old participated in this split mouth randomised crossover study. The control intervention comprised of the administration of 1. Read More

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December 2018
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Fabrication of Poly(acrylic acid)/Boron Nitride Composite Hydrogels with Excellent Mechanical Properties and Rapid Self-Healing Through Hierarchically Physical Interactions.

Nanoscale Res Lett 2018 Dec 5;13(1):393. Epub 2018 Dec 5.

Institute for Frontier Materials, Deakin University, Locked Bag 20000, Geelong, Victoria, 3220, Australia.

Many living tissues possess excellent mechanical properties and self-healing ability. To mimic these living tissues, a series of novel composite hydrogels, poly(acrylic acid)/surface-modified boron nitride nanosheets (PAA/BNNS-NH) were fabricated simply through hierarchically physical interactions: molecular-scale metal coordination interaction between -COOH of PAA and Fe and nanoscale H-bond between -COOH of PAA and -NH of BNNS-NH. The composite hydrogels exhibit both excellent mechanical properties (including enhanced fracture stress, elongation, toughness, Young's modulus, and dissipated energy) and rapid healing ability without any external stimulus. Read More

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December 2018
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Adsorption of Tetracycline with Reduced Graphene Oxide Decorated with MnFeO Nanoparticles.

Nanoscale Res Lett 2018 Dec 5;13(1):396. Epub 2018 Dec 5.

Jiangsu Provincial Key Laboratory of Materials Cycling and Pollution Control, School of Environment, Nanjing Normal University, Nanjing, 210023, China.

Nanomaterials were widely used as efficient adsorbents for environmental remediation of tetracycline pollution. However, the separation of the adsorbents posed the challenge to their practical applications. In this study, we grew magnetic MnFeO nanoparticles on the reduced graphene oxide (rGO) to form MnFeO/rGO nanocomposite with a one-step method. Read More

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December 2018
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A wheat protein kinase gene TaSnRK2.9-5A associated with yield contributing traits.

Theor Appl Genet 2018 Dec 5. Epub 2018 Dec 5.

National Key Facility for Crop Gene Resources and Genetic Improvement, Institute of Crop Sciences, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.

Key Message: We developed breeder-friendly high-throughput and cost-effective KASP marker for marker-assisted selection for grain yield related traits in wheat. Plant-specific protein kinase, SnRK2s, is a major family of signaling genes associated with metabolic regulations, nutrient utilization and response to external stimuli. In the present study, three copies of TaSnRK2. Read More

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December 2018
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External temperature control of lymphatic drainage of thermo-sensitive nanomaterials.

Biomater Sci 2018 Dec 6. Epub 2018 Dec 6.

Department of Biomedical Engineering, University of Minnesota, 7-105 Hasselmo Hall, 312 Church Street S. E., Minneapolis, Minnesota 55455, USA.

Nano-carrier-facilitated delivery of bioactive molecules into lymph nodes (LNs) has found application in the treatment and diagnosis of numerous immune-related diseases. Much work has focused on optimization of physicochemical properties of the nano-carrier to enhance lymphatic drainage passively, whereas active modulation of the quantity and timing of lymphatic delivery remains a significant challenge. Here, inspired by the success of thermo-modulation of tumor targeting, we have developed a simple external temperature control strategy to regulate the distribution of thermo-sensitive nanomaterials between the injection site and draining LNs. Read More

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December 2018

High-performance solar-blind SnO nanowire photodetectors assembled using optical tweezers.

Nanoscale 2018 Dec 6. Epub 2018 Dec 6.

Hunan Key Laboratory for Super Microstructure and Ultrafast Process, School of Physics and Electronics, Central South University, Changsha, Hunan 410083, P. R. China. and Department of Physics and Astronomy, University of Rochester, Rochester, NY 14627, USA.

One-dimensional semiconducting SnO2 nanowires with wide bandgaps are promising candidates to build many important optoelectronic devices. Because building these devices involves the assembly of nanowires into complex structures, manipulation of the active materials needs to be done with high spatial precision. In this paper, an optical tweezer system, comprising a spatial light-modulator, a microscope, and optical elements, is used to individually trap, transfer, and assemble SnO2 nanowires into two-terminal photodetectors in a liquid environment. Read More

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December 2018
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Impact of Intravenous Fluid Challenge Infusion Time on Macrocirculation and Endothelial Glycocalyx in Surgical and Critically Ill Patients.

Biomed Res Int 2018 1;2018:8925345. Epub 2018 Nov 1.

Dpt. of Anesthesiology and Intensive Care Medicine, Faculty of Medicine in Plzen, Charles University, Plzen, Czech Republic.

The fluid challenge (FC) is a well-established test of preload reserve. Only limited data exist in regard to the FC efficacy based on infusion time. Slow administration may be associated with lack of effect based on fluid redistribution and external conditions changes. Read More

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November 2018

Assessment of quality control system by sigma metrics and quality goal index ratio: A roadmap towards preparation for NABL.

World J Methodol 2018 Nov 29;8(3):44-50. Epub 2018 Nov 29.

Department of Biochemistry, Pt. B.D. Sharma, University of Health Sciences, Rohtak 124001, Haryana, India.

Aim: To study sigma metrics and quality goal index ratio (QGI).

Methods: The retrospective study was conducted at the Clinical Biochemistry Laboratory, PGIMS, Rohtak, which recently became a National Accreditation Board for Testing and Calibration of Laboratories accredited lab as per the International Organization for Standardization 15189:2012 and provides service to a > 1700-bed tertiary care hospital. Data of 16 analytes was extracted over a period of one year from January 2017 to December 2017 for calculation of precision, accuracy, sigma metrics, total error, and QGI. Read More

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November 2018

A quick and simple method for the determination of ivermectin in dog plasma by LC-MS/MS.

MethodsX 2018 17;5:1503-1507. Epub 2018 Nov 17.

Alma Mater Studiorum - University of Bologna, Department of Veterinary Medical Sciences, Via Tolara di Sopra 50, 40064, Ozzano dell'Emilia, BO, Italy.

Ivermectin is an endectocide belonging to the macrocyclic lactone class, commonly used in dogs as a heartworm preventative and for the treatment of several external and internal parasite infections. Among the analytical methods for ivermectin determination in plasma available in literature, many require a laborious clean-up step on SPE cartridge, and use fluorescence detection instead of the more reliable mass spectrometry. In the context of a project aimed at its pharmacokinetic evaluation in this species, a liquid chromatography-tandem mass spectrometry method for the determination of ivermectin in dog plasma was developed and validated, using blank plasma provided by a local canine blood transfusion service. Read More

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November 2018

ShapeGTB: the role of local DNA shape in prioritization of functional variants in human promoters with machine learning.

PeerJ 2018 29;6:e5742. Epub 2018 Nov 29.

Laboratory of Bioinformatics and Biostatistics, Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland.

Motivation: The identification of functional sequence variations in regulatory DNA regions is one of the major challenges of modern genetics. Here, we report results of a combined multifactor analysis of properties characterizing functional sequence variants located in promoter regions of genes.

Results: We demonstrate that GC-content of the local sequence fragments and local DNA shape features play significant role in prioritization of functional variants and outscore features related to histone modifications, transcription factors binding sites, or evolutionary conservation descriptors. Read More

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November 2018
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Safety and feasibility of an interactive workshop and facilitated outdoor walking group compared to a workshop alone in increasing outdoor walking activity among older adults: a pilot randomized controlled trial.

Pilot Feasibility Stud 2018 29;4:179. Epub 2018 Nov 29.

7Department of Physical Therapy, University of Toronto, Toronto, Ontario Canada.

Background: Limited outdoor walking is a marker of frailty and a risk factor for decline in mobility and self-care functioning, social isolation, and reduced health-related quality of life (HRQL). Objectives were to evaluate the safety, feasibility, and preliminary effect of a supervised outdoor walking group and interactive workshop compared to the workshop alone in increasing outdoor walking activity and identify an optimal method for estimating outdoor walking activity among older adults who infrequently walk outdoors.

Methods: A pilot 2-parallel-group randomized controlled trial was conducted. Read More

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November 2018
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Identification of a HIV Gp41-Specific Human Monoclonal Antibody With Potent Antibody-Dependent Cellular Cytotoxicity.

Front Immunol 2018 16;9:2613. Epub 2018 Nov 16.

AIDS Institute, Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong.

Antibody-Dependent Cellular Cytotoxicity (ADCC) is a major mechanism of protection against viral infections . Identification of HIV-1-specific monoclonal antibodies (mAbs) with potent ADCC activity may help develop an effective HIV-1 vaccine. In present study, we isolated such human mAb, designated E10, from an HIV-1-infected patient sample by single B cell sorting and single cell PCR. Read More

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November 2018

Iron Dysregulation and Dormant Microbes as Causative Agents for Impaired Blood Rheology and Pathological Clotting in Alzheimer's Type Dementia.

Front Neurosci 2018 16;12:851. Epub 2018 Nov 16.

Department of Physiological Sciences, Stellenbosch University, Stellenbosch, South Africa.

Alzheimer's disease and other similar dementias are debilitating neurodegenerative disorders whose etiology and pathogenesis remain largely unknown, even after decades of research. With the anticipated increase in prevalence of Alzheimer's type dementias among the more susceptible aging population, the need for disease-modifying treatments is urgent. While various hypotheses have been put forward over the last few decades, we suggest that Alzheimer's type dementias are triggered by external environmental factors, co-expressing in individuals with specific genetic susceptibilities. Read More

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November 2018
2 Reads

Nomogram application to predict overall and cancer-specific survival in osteosarcoma.

Cancer Manag Res 2018 8;10:5439-5450. Epub 2018 Nov 8.

Department of Orthopedics, Guangzhou First People's Hospital, Guangzhou Medical University, School of Medicine, South China University of Technology, Guangzhou, Guangdong 510180, People's Republic of China,

Purpose: A prognostic nomogram was applied to predict survival in osteosarcoma patients.

Patients And Methods: Data collected from 2,195 osteosarcoma patients in the Surveillance, Epidemiology, and End Results (SEER) database between 1983 and 2014 were analyzed. Independent prognostic factors were identified via univariate and multivariate Cox analyses. Read More

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November 2018
2 Reads

Transformation between meron and skyrmion topological spin textures in a chiral magnet.

Nature 2018 12 5;564(7734):95-98. Epub 2018 Dec 5.

RIKEN Center for Emergent Matter Science (CEMS), Wako, Japan.

Crystal lattices with tetragonal or hexagonal structure often exhibit structural transitions in response to external stimuli. Similar behaviour is anticipated for the lattice forms of topological spin textures, such as lattices composed of merons and antimerons or skyrmions and antiskyrmions (types of vortex related to the distribution of electron spins in a magnetic field), but has yet to be verified experimentally. Here we report real-space observations of spin textures in a thin plate of the chiral-lattice magnet CoZnMn, which exhibits in-plane magnetic anisotropy. Read More

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December 2018
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Soft-tissue evidence for homeothermy and crypsis in a Jurassic ichthyosaur.

Nature 2018 Dec 5. Epub 2018 Dec 5.

Department of Geology, Lund University, Lund, Sweden.

Ichthyosaurs are extinct marine reptiles that display a notable external similarity to modern toothed whales. Here we show that this resemblance is more than skin deep. We apply a multidisciplinary experimental approach to characterize the cellular and molecular composition of integumental tissues in an exceptionally preserved specimen of the Early Jurassic ichthyosaur Stenopterygius. Read More

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December 2018

Daily changes in phytoplankton lipidomes reveal mechanisms of energy storage in the open ocean.

Nat Commun 2018 Dec 5;9(1):5179. Epub 2018 Dec 5.

Department of Marine Chemistry and Geochemistry, Woods Hole Oceanographic Institution, Woods Hole, MA, 02543, USA.

Sunlight is the dominant control on phytoplankton biosynthetic activity, and darkness deprives them of their primary external energy source. Changes in the biochemical composition of phytoplankton communities over diel light cycles and attendant consequences for carbon and energy flux in environments remain poorly elucidated. Here we use lipidomic data from the North Pacific subtropical gyre to show that biosynthesis of energy-rich triacylglycerols (TAGs) by eukaryotic nanophytoplankton during the day and their subsequent consumption at night drives a large and previously uncharacterized daily carbon cycle. Read More

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December 2018

ANTIBODY-MEDIATED PROTECTIVE MECHANISMS INDUCED BY A TRIVALENT PARAINFLUENZA-VECTORED EBOLAVIRUS VACCINE.

J Virol 2018 Dec 5. Epub 2018 Dec 5.

Department of Pathology, University of Texas Medical Branch, Galveston, TX

Ebolaviruses Zaire (EBOV), Bundibugyo (BDBV) and Sudan (SUDV) cause human disease with high case fatality rates. Experimental monovalent vaccines, which all utilize the sole envelope glycoprotein (GP), do not protect against heterologous ebolaviruses. Human parainfluenza virus type 3-vectored vaccines offer benefits including needle-free administration and induction of mucosal responses in the respiratory tract. Read More

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December 2018

Debridement, internal fixation and staged autogenous bone graft for the management of infected femoral non-union.

Injury 2018 Nov 22. Epub 2018 Nov 22.

Hip Department - Orthopedic and Trauma v, I.R.C.C.S. Policlinico San Donato, 20097, San Donato Mil.se, Milan, Italy; Division of Orthopaedic Surgery, McMaster University, Canada.

An infected non-union is a major and potentially devastating complication following bone fractures. It is often debilitating for the patients, physically and psychologically, because of its long healing period and emotional toll on patient and caregivers. Different surgical procedures (in one or two stages) are described in literature for its treatment. Read More

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November 2018

Intercalary allograft reconstruction in a patient with large tibial defect: Case report.

Injury 2018 Oct 16. Epub 2018 Oct 16.

Orthopaedic and Traumatology Division, Department of Medicine and Science of Aging, University of Study "G. d'Annunzio" Chieti-Pescara, Italy.

A fit 26 year-old-man presented to our Department with an open fracture of the left tibial shaft (AO 42-C3). The fracture was initially treated with an External Fixator, which was replaced by an intramedullary Grosse Kempf nail after 4 months. In the following year he developed an atrophic non-union and we witnessed the increasing bone resorption at the fracture site which led to the nail breakage. Read More

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October 2018
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Performance of gimbal-based dynamic tumor tracking for treating liver carcinoma.

Radiat Oncol 2018 Dec 5;13(1):242. Epub 2018 Dec 5.

Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsstraße 27, 91054, Erlangen, Germany.

Background: Since the introduction of tumor tracking in radiotherapy, it is possible to ensure a precise irradiation of moving targets. To follow the tumor movement, most systems rely on the detection of implanted markers and correlation models between the internal and external patient movement. This study reports the clinical workflow and first results of the dynamic tumor tracking (DTT) performance for patients with liver carcinoma at the Vero SBRT system of the University Hospital Erlangen regarding the detection of the internal marker and the changes of the determined correlation models. Read More

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December 2018

Prognostic factors affecting clinical outcomes after arthroscopic rotator cuff repair: importance of functional recovery by 3 months after surgery.

J Orthop Surg Res 2018 Dec 5;13(1):310. Epub 2018 Dec 5.

Department of Orthopedic Surgery, Kurume University Medical Center, 155-1 Kokubu-machi, Kurume, Fukuoka, 839-0863, Japan.

Background: To examine important factors that affect clinical outcomes following arthroscopic rotator cuff repair (ARCR).

Methods: Among 163 patients who underwent ARCR, we included 71 shoulders in 71 patients whose progress was monitored for > 2 years, postoperatively. We divided the patients into groups A (scores ≥ 83 points, 59 patients) and B (scores < 83 points, 12 patients) using the Japanese Orthopedic Association (JOA) score at 24 months. Read More

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December 2018
2 Reads

Retrospective evaluation of perioperative and short term clinical outcomes in appendicular long bone skeleton fractures repaired via the string of pearls (SOP) locking plate system.

BMC Vet Res 2018 Dec 5;14(1):386. Epub 2018 Dec 5.

Memphis Veterinary Specialists, 555 Trinity Creek Cove, Cordova, TN, 38018, USA.

Background: Internal plate fixation and, more recently, locking plate fixation are commonly used in the repair of fractures in small animal surgery. This retrospective study reviewed the use of the String of Pearls locking plate system in the fixation/repair of appendicular long bone skeleton fractures in 31 small animal veterinary patients (33 fractures).

Results: Major complications necessitating revision surgery occurred in 7/33 (21%), with implant failure as the inciting cause in all cases. Read More

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December 2018
2 Reads

Postural Control Entropy Is Increased When Adopting an External Focus of Attention.

Motor Control 2018 Dec 5:1-13. Epub 2018 Dec 5.

1 The University of North Carolina at Greensboro.

Falls in older adults are a public health challenge due to their influence on well-being and health-care costs. One way to address this challenge is to discover new methods to enhance postural control in older adults so they are better prepared to maintain an upright stance. Older and younger adults (N = 32) performed a static balance task on a force plate with no instructions, internal focus instructions, or external focus instructions. Read More

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December 2018

Visible-light-Driven External-Reductant-Free Cross-Electrophile Couplings of Tetraalkyl Ammonium Salts.

J Am Chem Soc 2018 Dec 6. Epub 2018 Dec 6.

Cross-electrophile couplings between two electrophiles are powerful and economic methods to generate C─C bonds in the presence of stoichiometric external reductants. Herein, we report a novel strategy to realize the first external-reductant-free cross-electrophile coupling via visible-light photoredox catalysis. A variety of tetraalkyl ammonium salts, bearing primary, secondary, and tertiary C─N bonds, undergo selective couplings with aldehydes/ketone and CO2. Read More

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December 2018