178 results match your criteria External Ear Malignant External Otitis


The Impact of using the term "Diabetic Ear" for the patients with Skull Base Osteomyelitis.

J Family Community Med 2019 Jan-Apr;26(1):23-29

Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Imam Abdulrahman Bin Faisal University, KFUH, Al-Khobar, Saudi Arabia.

Background: Diabetes and ear disease are some of the most widespread health concerns. The focus here is on the impact of using the term "Diabetic Ear" for patients with skull base osteomyelitis (SBM) in the context of malignant otitis externa (MOE). The aim of this study was to discover the awareness of general practitioners (GPs), residents, specialists, and consultants at Primary Health Care Centers about necrotizing otitis externa (NOE), also known previously as malignant external otitis (MOE), assess their deficiencies and provide solutions; also assist them for the early detection and possible prevention of diabetes- related ear diseases and their complications. Read More

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http://dx.doi.org/10.4103/jfcm.JFCM_187_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335838PMC
January 2019
4 Reads

FDG-PET/CT for diagnosis and follow-up of necrotizing (malignant) external otitis.

Laryngoscope 2018 Dec 14. Epub 2018 Dec 14.

Department of Otolaryngology-Head and Neck Surgery, Petach Tikva, Israel.

Objective: Imaging is important for the diagnosis and follow-up of necrotizing external otitis (NEO). The best imaging modality is controversy. To suggest 2-deoxy-2-[fluorine-18] fluoro-D-glucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) as an alternative to technetium-99m and gallium-67 scans for diagnosis and assessment of response to treatment for patients with NEO. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.27526
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http://dx.doi.org/10.1002/lary.27526DOI Listing
December 2018
7 Reads

The Role of Surgical Debridement in Cases of Refractory Malignant Otitis Externa.

Indian J Otolaryngol Head Neck Surg 2018 Dec 18;70(4):549-554. Epub 2018 Jun 18.

Sri Guru Ram Das Institute of Health Sciences and Research Amritsar, 27-C; Sant Avenue, The Mall, Amritsar, 143001 India.

Malignant Otitis externa is a necrotizing condition of external ear involving causing the osteomyelitis of the bone and surrounding soft tissue leading to multiple cranial nerve palsies. Though most patients respond to oral ciprofloxacin but due to emerging resistance cases of refractory malignant otitis externa which are unresponsive to antibiotic therapy for at least 6 weeks are being encountered lately. A study of 20 patients of refractory malignant otitis Externa was conducted at a tertiary care centre in north India; 10 patients were randomly allotted in group A and group B each. Read More

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http://dx.doi.org/10.1007/s12070-018-1426-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224839PMC
December 2018
10 Reads

Diagnosis and treatment of necrotising otitis externa and diabetic foot osteomyelitis - similarities and differences.

J Laryngol Otol 2018 Sep 28;132(9):775-779. Epub 2018 Aug 28.

Department of Otolaryngology - Head and Neck Surgery,Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University in the Negev,Beer-Sheva,Israel.

Objective: Necrotising otitis externa is a severe inflammatory process affecting soft tissue and bone, mostly in diabetic patients. Diabetic patients are also at risk of diabetic foot osteomyelitis, another inflammatory condition involving soft tissue and bone. This review aimed to describe the similarities and differences of these entities in an attempt to further advance the management of necrotising otitis externa. Read More

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http://dx.doi.org/10.1017/S002221511800138XDOI Listing
September 2018
4 Reads

Malignant external otitis following radiotherapy for oral cancer: A case report.

Medicine (Baltimore) 2018 May;97(21):e10898

Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, Yokohama, Japan.

Rationale: Although an ototoxicity is well-known as adverse event of the radiotherapy, it is not widely known that immunosuppressed patients who underwent radiotherapy in head and neck region have risk of malignant external otitis.

Patient Concerns: A 68-year-old man with diabetes, who had been diagnosed as intraosseous squamous cell carcinoma of the right mandible, underwent surgical resection. He received a total of 60 Gy/30Fr postoperative radiation. Read More

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http://dx.doi.org/10.1097/MD.0000000000010898DOI Listing
May 2018
3 Reads

[The tumors of the ear].

Presse Med 2017 Nov 31;46(11):1079-1088. Epub 2017 Oct 31.

Hôpital Robert-Debré, departement d'oto-rhino-laryngologie, 51100 Reims, France; Université de Reims Champagne-Ardenne, faculté de médecine, 51100 Reims, France.

Any cutaneous lesion of the outer ear must be managed jointly by a dermatologist and an ENT, regardless of the age of the patient. The presence of a malignant cutaneous carcinoma (Squamous cell carcinoma or melanoma) of the pavilion requires a minimum extension assessment by a cervical ultrasound, CT-scan and MRI will be prescribed according to the degree of infiltration and the presence of clinics signs (lymphadenopathy, facial paralysis, cognitive impairment). A polyp of the external auditory meatus must be systematically biopsied in consultation and, if necessary, in the operating room with fresh anatomopathological analysis. Read More

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http://dx.doi.org/10.1016/j.lpm.2017.09.016DOI Listing
November 2017
1 Read

The treatment of pseudoaneurysms with flow diverters after malignant otitis externa.

Interv Neuroradiol 2017 Dec 9;23(6):609-613. Epub 2017 Oct 9.

4 Department of Radiology, Faculty of Medicine, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary.

Background We report a case of bilateral malignant otitis externa complicated with bilateral petrous internal carotid artery pseudoaneurysms and their successful treatment with a flow diverter. Case report A 68-year-old woman with serious complications of type II diabetes mellitus had malignant otitis externa on the right side. She was treated with combined antibiotic therapy and underwent mastoidectomy for mastoiditis. Read More

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http://dx.doi.org/10.1177/1591019917729804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814079PMC
December 2017
12 Reads

[External auditory canal cholesteatoma].

Pan Afr Med J 2016 27;24:269. Epub 2016 Jul 27.

Service d'Oto-rhino-laryngologie et Chirurgie Cervico-Faciale, CHU Mohammed VI, Oujda, Maroc.

External auditory canal cholesteatoma is defined as an accumulation of keratin leading to osteolytic bony erosion. It is a rare or underdiagnosed otologic entity. Our study aims to illustrate one case of external auditory canal cholesteatoma. Read More

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http://dx.doi.org/10.11604/pamj.2016.24.269.5977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267907PMC
March 2017
7 Reads

Invasive keratinizing squamous cell carcinoma of the left external auricular canal and the middle ear - case report.

Rom J Morphol Embryol 2017 ;58(4):1519-1524

Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, "Titu Maiorescu" University, Bucharest, Romania; Department of Anatomy, Faculty of Dental Medicine, "Ovidius" University of Constanta, Romania;

The rather low incidence of auricular neoplasms irrespective of localization is likely to cause confusion of diagnosis with the more frequent benign ear pathology. Because of this, the elapsed time until confirmation of the diagnosis facilitates the evolution of the disease to the detriment of the patient's health. The diagnosis of an ear neoplasm can hide under the ordinary appearance of external otitis, chronic otorrhea or episodes of various types of ear pain. Read More

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September 2018
1 Read

Propionibacterium skull base osteomyelitis complicated by internal carotid artery pseudoaneurysm.

Laryngoscope 2017 10 15;127(10):2337-2339. Epub 2016 Nov 15.

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, U.S.A.

The microbiology of skull base osteomyelitis (SBO) is evolving. We present here the first case of SBO caused by Propionibacterium acnes leading to the development of a pseudoaneurysm of the internal carotid artery. Otolaryngologists should recognize this pathogen as a potential cause of invasive temporal bone infection to optimize prompt diagnosis and treatment. Read More

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http://doi.wiley.com/10.1002/lary.26412
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http://dx.doi.org/10.1002/lary.26412DOI Listing
October 2017
3 Reads

Scedosporium apiospermum: a rare cause of malignant otitis externa.

BMJ Case Rep 2016 Sep 9;2016. Epub 2016 Sep 9.

Department of ENT, South Devon NHS Foundation Trust, Torquay, Devon, UK.

A 79-year-old man, with a history of well-controlled diabetes mellitus, presented with left-sided otalgia. With an initial diagnosis of simple otitis externa, he was discharged on topical drops. He represented 2 months later with worsening otalgia and discharge. Read More

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http://dx.doi.org/10.1136/bcr-2016-217015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020719PMC
September 2016
2 Reads

Malignant external otitis: Factors predicting patient outcomes.

Am J Otolaryngol 2016 Sep-Oct;37(5):425-30. Epub 2016 May 6.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Otolaryngology-Head and Neck Surgery, Meir Medical Center, Kfar Saba, Israel. Electronic address:

Objective: Malignant external otitis (MEO) is an aggressive infection, primarily affecting elderly diabetic patients. It begins in the external ear canal and spreads to adjacent structures. This study investigated the clinical characteristics of patients diagnosed and treated for MEO and analyzed factors affecting patient outcomes. Read More

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http://dx.doi.org/10.1016/j.amjoto.2016.04.005DOI Listing
March 2017
4 Reads

Malignant external otitis in Spain.

Acta Otorrinolaringol Esp 2017 Jan - Feb;68(1):23-28. Epub 2016 May 27.

Servicio de Otorrinolaringología Hospital Universitario de La Ribera, Alzira, Valencia, España.

Introduction: Malignant external otitis is a necrotizing infection, which extends from the squamous epithelium of the ear canal to the adjacent tissue. The objective of the study was to investigate its incidence and other epidemiological data in Spain, reporting the largest case series to date.

Methods: A descriptive, retrospective study of the Spanish population was carried out using the minimum basic data set (MBDS) based on data of patients admitted to hospitals in the 2008-2013 period. Read More

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http://dx.doi.org/10.1016/j.otorri.2016.02.010DOI Listing
February 2018

Malignant Otitis Externa and Stroke.

Eur J Case Rep Intern Med 2016 14;3(4):000387. Epub 2016 Apr 14.

Department of Internal Medicine, Hospital de Egas Moniz, Lisboa, Portugal.

Malignant otitis externa (MOE) is an aggressive but benign entity which evolves into skull base osteomyelitis. An 81-year-old female patient was admitted for left hemiparesis and homonymous hemianopia. She complained of headache radiating to the right cervical area. Read More

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http://dx.doi.org/10.12890/2016_000387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346865PMC

Hypoglossal paresis as the only complication of malignant otitis externa.

B-ENT 2015 ;11(3):235-8

Background: Ipsilateral hypoglossal nerve (XII) paresis has never been reported as the first and only complication of malignant otitis external (MOE).

Case Report: A 73-year-old diabetic male with persistent left temporomandibular joint ache and ear fullness was admitted with the diagnosis of MOE. He received intravenous ciprofloxacin for 14 days and then continued with oral administration (per os). Read More

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January 2016
2 Reads

Temporomandibular joint disorder from skull-base osteomyelitis: a case report.

Maxillofac Plast Reconstr Surg 2015 Dec 31;37(1):39. Epub 2015 Oct 31.

Department of Oral and Maxillofacial surgery, Dong-a University Hospital, Daesingongwon-ro 26, Seo-gu, Busan, 602-715 Korea.

Skull-base osteomyelitis is a rare disease affecting the medulla of the temporal, sphenoid, and occipital bones. In general, it occurs due to external ear canal infections caused by malignant external otitis. Skull-base osteomyelitis usually affects elderly diabetic patients. Read More

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http://www.jkamprs.com/content/pdf/s40902-015-0041-1.pdf
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http://www.jkamprs.com/content/37/1/39
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http://dx.doi.org/10.1186/s40902-015-0041-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628617PMC
December 2015
2 Reads

Radiology of external ear: indications, normal anatomy, and pathological processes.

Radiologia 2016 May-Jun;58(3):189-98. Epub 2015 Oct 12.

Área Clínica de Imagen Médica, Hospital Universitario y Politécnico La Fe, Valencia, España.

The external ear is accessible to direct examination; the clinical history and otoscopy are sufficient to diagnose and treat most diseases of the external ear. We aim to describe the normal anatomy of the external ear, specify the indications for imaging tests, and review the clinical and radiological manifestations of the most common diseases affecting the external ear. We classify these diseases according to their origin into congenital, inflammatory, infectious, or traumatic disease or benign bone tumors or malignant tumors. Read More

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http://dx.doi.org/10.1016/j.rx.2015.08.003DOI Listing
November 2017
3 Reads

Malignant otitis externa in a healthy non-diabetic patient.

Eur Arch Otorhinolaryngol 2016 Aug 2;273(8):2261-5. Epub 2015 Aug 2.

Department of Otolaryngology-Head and Neck Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou, 510515, China.

A healthy 60-year-old male was initially treated for external otitis, and subsequently received multiple surgeries including abscess drainage, temporal bone debridement, canaloplasty of the external auditory meatus, and fistula excision and was treated with numerous antibiotics at another hospital over a 1-year period. He was seen at our hospital on February 14, 2014 with a complaint of a non-healing wound behind the left ear and drainage of purulent fluid. He had no history of diabetes mellitus or compromised immune function. Read More

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http://dx.doi.org/10.1007/s00405-015-3738-yDOI Listing
August 2016
9 Reads

Malignant Otitis Externa - A Retrospective Study of 15 Patients Treated in a Tertiary Healthcare Center.

J Int Adv Otol 2015 Apr;11(1):72-6

Department of Otorhinolaryngology, K S Hegde Medical Academy, Karnataka, India.

Objective: Malignant otitis externa (MOE) is an uncommon but potentially fatal disease of the external auditory canal. The study aimed at evaluating the demographic profile, coexisting disabilities, clinical presentations, and management of MOE.

Materials And Methods: This is a retrospective study of patients with MOE who were treated at the Otorhinolaryngology Department of our institution. Read More

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http://dx.doi.org/10.5152/iao.2015.430DOI Listing
April 2015
6 Reads

Malignant otitis externa.

Ear Nose Throat J 2015 Apr-May;94(4-5):136-8

Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA.

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November 2016
3 Reads

Cholesteatoma and osteoradionecrosis after radio­therapy of the temporal bone: Surgical aspects.

Rev Laryngol Otol Rhinol (Bord) 2015;136(4):163-5

Introduction: The treatment for head and neck cancer with radiotherapy can cause different alterations of the auditory system. We report two cases of chronic otitis of the external and middle ear secondary to osteoradionecrosis of the temporal bone. This article aims to report the experience of the surgical approach in such condition. Read More

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Squamous cell carcinoma of the external auditory canal in a patient with non-resolving ear discharge.

Malays Fam Physician 2015 31;10(2):52-4. Epub 2015 Aug 31.

Othman bin Abdullah Department of Pathology, Hospital Sultan Abdul Halim, Kedah, Malaysia.

Discharging ear is a common symptom in the primary care and private general clinics. Most of the cases are treated with the antibiotic ear drops for otitis externa or otitis media. However, despite an adequate standard therapy, a malignant tumour can also be present with non-specific symptom such as ear discharge, especially in the case of persistent ear discharge. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826582PMC
April 2016
1 Read

Central skull base osteomyelitis: new insights and implications for diagnosis and treatment.

Eur Arch Otorhinolaryngol 2015 May 9;272(5):1269-76. Epub 2014 Nov 9.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Freiburg, Killianstrasse 5, 79106, Freiburg, Germany.

Central skull base osteomyelitis (SBO) is a life-threatening disease originating from ear and from sinonasal infections. The intention of this study was to evaluate contemporary trends in etiology, diagnosis, management, and outcome of SBO and to draw the clinician's attention on this probably underestimated disease. Over a 6-year period we performed this systematic study in an academic quaternary medical care and skull base center including 20 patients (mean age 63. Read More

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http://link.springer.com/content/pdf/10.1007/s00405-014-3390
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http://link.springer.com/10.1007/s00405-014-3390-y
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http://dx.doi.org/10.1007/s00405-014-3390-yDOI Listing
May 2015
4 Reads

[Ear diseases and diabetes mellitus].

HNO 2014 Nov;62(11):823-32

Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Plastische Operationen, Krankenhaus Martha-Maria Halle-Dölau, Röntgenstr. 1, 06120, Halle (Saale), Deutschland,

In the literature there is very little information about the importance of diabetes mellitus for ear diseases. Therefore, this article gives an overview about contact points between endocrinological and otological problems in patients with diseases of the ear and pre-existing diabetes mellitus. In particular the focus is on the impact of diabetes mellitus on patients with external otitis, malignant external otitis, otitis media, sudden sensorineural hearing loss and slowly progressive hearing loss. Read More

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http://dx.doi.org/10.1007/s00106-014-2902-9DOI Listing
November 2014
2 Reads

Osteomyelitis of the temporal bone: terminology, diagnosis, and management.

J Neurol Surg B Skull Base 2014 Oct 26;75(5):324-31. Epub 2014 Jun 26.

Department of Otolaryngology - Head & Neck Surgery, Kasturba Medical College, Mangalore (Manipal University), Mangalore, Karnataka, India.

Objectives To review the terminology, clinical features, and management of temporal bone osteomyelitis. Design and Setting Prospective study in a tertiary care center from 2001 to 2008. Participants Twenty patients visiting the outpatient department diagnosed with osteomyelitis of the temporal bone. Read More

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http://dx.doi.org/10.1055/s-0034-1372468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176546PMC
October 2014
17 Reads
3 Citations

Diagnosis and surgical treatment of a malignant trichoepithelioma of the ear canal in a pet rabbit (Oryctolagus cuniculus).

J Am Vet Med Assoc 2014 Jul;245(2):227-31

Departments of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706.

Case Description: A 10-year-old spayed female Holland Lop-mix pet rabbit (Oryctolagus cuniculus) was evaluated because of purulent-hemorrhagic discharge from the right ear canal and a suspected mass within that ear canal.

Clinical Findings: Results of contrast-enhanced CT, video otoscopy, and histologic examination of endoscopic tissue biopsy samples indicated severe otitis media and externa and a benign trichoepithelioma of the right ear canal.

Treatment And Outcome: Total ear canal ablation and lateral bulla osteotomy were performed. Read More

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http://dx.doi.org/10.2460/javma.245.2.227DOI Listing
July 2014
13 Reads

B-cell malignant lymphoma presenting as otitis media and mastoiditis associated with sinus thrombosis.

Case Rep Neurol 2014 May 15;6(2):161-5. Epub 2014 May 15.

Department of Neurosurgery, Aomori Prefectural Central Hospital, Aomori, Hirosaki, Japan.

Cerebral venous thrombosis as a manifestation of paraneoplastic angitis and otitis media, revealing non-Hodgkin B-cell lymphoma (NHBL), is extremely rare. A 57-year-old woman presented with headache, auditory disturbance and recalcitrant otitis media. Magnetic resonance imaging showed brain edema in the temporal lobe and transverse sinus thrombosis. Read More

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https://www.karger.com/Article/FullText/362114
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http://dx.doi.org/10.1159/000362114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049015PMC
May 2014
5 Reads

Technetium-99m (⁹⁹mTc)-labelled sulesomab in the management of malignant external otitis: is there any role?

Eur Arch Otorhinolaryngol 2015 Jun 18;272(6):1377-82. Epub 2014 Feb 18.

Department of Otorhinolaryngology, University of Messina, Messina, Italy,

We report two cases of malignant external otitis (MEO) evaluated with Technetium-99m((99m)Tc)-labelled sulesomab. Two patients affected by MEO are presented, together with a literature review. Both patients were studied with clinical examination, ear discharge culture, radiological imaging, blood exams, (99m)Tc Sulesomab, and treated with antibiotic therapy. Read More

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http://dx.doi.org/10.1007/s00405-014-2938-1DOI Listing
June 2015
1 Read

Survival outcomes of patients with temporal bone squamous cell carcinoma with different invasion patterns.

Head Neck 2015 Feb 12;37(2):188-96. Epub 2014 Feb 12.

Department of Otology and Skull Base Surgery, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China.

Background: The correlation between the survival rate and various invasion patterns of patients with temporal bone squamous cell carcinoma (SCC) is unclear. This study was performed to compare the survival outcomes of these patients to disclose the correlation.

Methods: The cases of 39 patients with temporal bone SCC who underwent surgery between January 2004 and December 2012 were reviewed. Read More

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http://doi.wiley.com/10.1002/hed.23576
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http://dx.doi.org/10.1002/hed.23576DOI Listing
February 2015
25 Reads

Synchronous malignant otitis externa and squamous cell carcinoma of the external auditory canal.

Case Rep Otolaryngol 2013 30;2013:837169. Epub 2013 Sep 30.

Department of Otolaryngology Head and Neck Surgery, Nepean Hospital, The University of Sydney, Sydney, NSW 2747, Australia.

Objectives. To discuss the management of a squamous cell carcinoma in the presence of malignant otitis externa. Study Design. Read More

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http://dx.doi.org/10.1155/2013/837169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806128PMC
November 2013
1 Read

Skull base osteomyelitis following a mastoidectomy.

Auris Nasus Larynx 2013 Dec 8;40(6):584-6. Epub 2013 Feb 8.

Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Hallym University, Seoul, South Korea.

Skull base osteomyelitis is a rare but life-threatening condition that is characterized by osteitis of the temporal bone and skull base. Although skull base osteomyelitis is recognized as a rare complication of malignant external otitis or middle ear infection, it may also occur following a mastoidectomy. We present a case of an 81-year-old woman who suffered severe otalgia with normal-looking EAC and tympanic membrane that developed six weeks following a canal wall up mastoidectomy. Read More

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http://dx.doi.org/10.1016/j.anl.2012.12.002DOI Listing
December 2013
3 Reads

Complicated necrotizing otitis externa.

Am J Otolaryngol 2013 Nov-Dec;34(6):706-9. Epub 2013 Aug 5.

University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA. Electronic address:

Necrotizing (malignant) otitis externa (NOE) is a rare and invasive infection originating in the external acoustic meatus seen most commonly in diabetes and other immunocompromised states. After a protracted course, disease can smolder and extend into the mastoid, skull base, dural sinuses, and intracranially. We present a case of NOE complicated by mastoiditis, dural sinus thrombosis, and Bezold's abscess in an uncontrolled diabetic presenting with a prolonged course of facial nerve palsy. Read More

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http://dx.doi.org/10.1016/j.amjoto.2013.07.003DOI Listing
October 2014
7 Reads

A case of orbital apex syndrome in a patient with malignant otitis externa.

J Pak Med Assoc 2013 Feb;63(2):271-3

Sections of Ophthalmology and Otolaryngology, Department of Surgery, Aga Khan University, Karachi.

A rare case of skull base infection with a rapid clinical course leading to visual loss and eventually death in a poorly-controlled diabetic patient is presented. A 37-year-old woman presented with a history of visual loss and painful protrusion of the right eye for the preceding 3 days.This was accompanied by vertigo and right-side facial weakness. Read More

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February 2013
1 Read

Quantitative measurement of m-RNA levels to assess expression of cyclooxygenase-II, inducible nitric oxide synthase and 12-lipoxygenase genes in middle ear cholesteatoma.

Eur Arch Otorhinolaryngol 2014 Jun 6;271(6):1471-5. Epub 2013 Jul 6.

ENT Department, Gazi University, Ankara, Turkey,

To assess expression of three main inflammatory genes, COX-II, ALOX-12 and i-NOS, quantitatively at transcriptional level in cholesteatoma matrix tissue. Ten patients who have chronic otitis media with primary acquired cholesteatoma were included in this study. Tissue samples obtained from cholesteatoma matrix and external ear canal skin (control tissue). Read More

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http://link.springer.com/content/pdf/10.1007/s00405-013-2614
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http://link.springer.com/10.1007/s00405-013-2614-x
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http://dx.doi.org/10.1007/s00405-013-2614-xDOI Listing
June 2014
3 Reads

Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa.

Cochrane Database Syst Rev 2013 May 31(5):CD004617. Epub 2013 May 31.

Department of Otolaryngology, Norfolk and Norwich University Hospital NHS Trust, Norwich, UK.

Background: Malignant, or necrotising, otitis externa is a potentially fatal infection of the external ear canal and surrounding soft tissue and bone. It may be complicated by involvement of cranial nerves, principally the facial nerves and the contents of the jugular foramen. It is an uncommon condition mainly found in the elderly or in diabetics. Read More

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http://dx.doi.org/10.1002/14651858.CD004617.pub3DOI Listing
May 2013
1 Read

Bisphosphonate-associated osteonecrosis of the external auditory canal.

J Laryngol Otol 2013 Jul 15;127 Suppl 2:S51-3. Epub 2013 May 15.

Department of Haematology, Adelaide Cancer Centre, Adelaide, South Australia, Australia.

Background: Osteonecrosis is a benign condition characterised by necrotic exposed bone, and is associated with bisphosphonate use. Osteonecrosis of the external auditory canal is rare, with only a few reported cases.

Method: Two case reports of temporal bone osteonecrosis are presented. Read More

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http://dx.doi.org/10.1017/S002221511300100XDOI Listing
July 2013
2 Reads

Necrotizing external otitis: a case series.

B-ENT 2013 ;9(1):61-6

Department of Otolaryngology Head and Neck Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Objectives: Necrotizing (malignant) external otitis (NEO) is a life-threatening progressive infection of the external auditory canal, mastoid, and skull base. Here, we review the clinical findings for a series of NEO patients.

Methodology: This case review study includes 18 patients with NEO (males: 11 (61. Read More

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July 2013
1 Read

[Eustachian orifice malignant melanoma: a case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2013 Feb;27(4):221-2

The patient, a 52 year old male was admitted to the hospital, because of right hearing loss before three months. Six months ago; the patient had the right former group sinusitis and nasal polyps, and had the right former group sinus open and polypectomy operation outside the hospital. The surgery was uneventful and the postoperative dressing was done. Read More

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February 2013
29 Reads

Osteonecrosis of the external auditory canal associated with oral bisphosphonate therapy: case report and literature review.

Otol Neurotol 2013 Feb;34(2):209-13

ENT Department, Olomouc University Hospital and Medical School, Palack] University, Olomouc, Czech Republic.

Objective: To present the first case of a patient with oral bisphosphonates-associated ear canal osteonecrosis (BPECO), review previously published cases, and suggest a definition of BPECO.

Patient: A 79-year-old woman with left otorrhea and earache was treated for otitis externa for 2 months. The examination revealed a deep floor of the left ear canal defect. Read More

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February 2013
84 Reads

Pseudomonas and Aspergillus interaction in malignant external otitis: risk of treatment failure.

Acta Otorhinolaryngol Ital 2012 Dec;32(6):416-9

ENT-Ear Surgery Unit, Az. Ospedaliera, via Giustiniani 2, Padua, Italy.

Malignant external otitis (MEO) is a rare infection of the temporal bone primarily affecting elderly patients and diabetics or immunocompromised individuals, which may have dismal prognosis if treatment is not prompt and adequate. Almost 95% of MEO cases reported in the literature are attributed to Pseudomonas aeruginosa, and this pathogen is isolated from aural drainage in > 90% of cases. However, in recent years fungal and polymicrobial temporal bone infections have been reported with increasing frequency. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552534PMC
December 2012
1 Read

Initial management of necrotizing external otitis: errors to avoid.

Eur Ann Otorhinolaryngol Head Neck Dis 2013 Jun 29;130(3):115-21. Epub 2012 Dec 29.

Groupement de coopération sanitaire, centre Antoine-Lacassagne, institut universitaire de la face et du cou, centre hospitalier universitaire de Nice, 31, avenue de Valombrose, 06107 Nice cedex 2, France.

Objectives: Diagnostic and therapeutic practice guidelines have been established for classical forms of benign otitis externa. However, these guidelines do not include unusual forms of the disease, especially "invasive" otitis externa. No consensual diagnostic flow diagram has been published in the literature, which frequently results in delayed diagnosis and inappropriate primary care management. Read More

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http://dx.doi.org/10.1016/j.anorl.2012.04.011DOI Listing
June 2013
18 Reads

[Bilateral bisphosphonate-associated osteonecrosis of the external ear canal : a rare case].

HNO 2012 Dec;60(12):1127-9

Klinik für Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie/Plastische Operationen, Helios-Klinikum Bad Saarow, Pieskower Str. 33, 15526, Bad Saarow, Deutschland.

Osteonecrosis of the mandible is a well-known and dreaded complication after the administration of bisphosphonates. Only a few cases of bisphosphonate-associated osteonecrosis of the external ear canal have been described. Especially after long-lasting bisphosphonate therapy, for example in patients with multiple myeloma, an ulceration of the floor of the bony external auditory canal should be treated surgically and be distinguished from radioosteonecrosis, malignant external otitis, or carcinoma of the external ear. Read More

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http://dx.doi.org/10.1007/s00106-012-2554-6DOI Listing
December 2012
2 Reads

Malignant otitis externa.

J Craniofac Surg 2012 Nov;23(6):1748-51

Otolaryngology Department, Cerrahpasa Medical School, Istanbul University, Istanbul, Turkey.

Objective: Malignant external otitis is a severe infection of the external auditory canal and skull base, which most often affects elderly patients with diabetes mellitus. This disease is still a serious disease associated with cranial nerve complications and high morbidity-mortality rate. Malignant otitis externa requires urgent diagnosis and treatment. Read More

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http://dx.doi.org/10.1097/SCS.0b013e31825e4d9aDOI Listing
November 2012
15 Reads

Clinical-scintigraphy discordance in a case of malignant external otitis.

Rev Esp Med Nucl Imagen Mol 2012 Sep 3;31(5):267-9. Epub 2012 Jan 3.

Servicio de Medicina Nuclear, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.

We report the case of an immunocompromised female patient with external otitis, who developed a picture of external otitis with poor response to conventional treatment and subsequent isolation of Pseudomona Aeruginosa in the ear secretion culture. The final diagnosis was malignant external otitis. Our objective is to describe the scintigraphic findings as well as to analyze their correlation with the clinical pattern and to evaluate the possible causes of the discordance found. Read More

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http://dx.doi.org/10.1016/j.remn.2011.11.003DOI Listing
September 2012
1 Read

The misdiagnosis of external auditory canal carcinoma.

Eur Arch Otorhinolaryngol 2013 May 25;270(5):1607-13. Epub 2012 Aug 25.

Department of Otology and Skull Base Surgery, Eye Ear Nose and Throat Hospital, Fudan University, Shanghai 200031, China.

External auditory canal (EAC) carcinomas are frequently misdiagnosed. The aim of this study was to conduct a review of misdiagnosed cases and analyze the factors involved. This study was a retrospective assessment. Read More

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http://dx.doi.org/10.1007/s00405-012-2159-4DOI Listing
May 2013
1 Read

[Imaging diagnosis of benign lesions of the external auditory canal].

Acta Otorrinolaringol Esp 2013 Jan-Feb;64(1):6-11. Epub 2012 Aug 15.

Servicio de Neurorradiología, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, España.

Introduction And Objectives: Benign lesions of the external auditory canal (EAC) are an infrequent cause of temporal bone CT scan requests. We are not usually well versed in the different pathologies located in the EAC, perhaps because it is "only" a conduit and the relevant anatomical structures are located in the middle and inner ear. Our objective was to improve knowledge of this structure by reviewing the different benign conditions found in this location. Read More

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http://dx.doi.org/10.1016/j.otorri.2012.06.004DOI Listing
February 2014
2 Reads

[External granulation otitis].

Vestn Otorinolaringol 2011 (4):33-4

Kafedra otorinolaringologii s klinikoĭ Sankt-Peterburgskogo gosudarstvennogo meditsinskogo universiteta im. akad. I.P. Pavlova.

The authors repot two cases of successful treatment of external granulation otitis. Taken together, the difficulties encountered in diagnostics of this condition, concomitant disorders aggravating pathological changes in the ear, and the malignant clinical course of the disease hamper the adequate management of external granulation otitis. Read More

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April 2016
1 Read

[Osteoradionecrosis of the temporal bone].

Otolaryngol Pol 2011 Sep;65(5 Suppl):85-92

Katedra i Klinika Otolaryngologii Warszawskiego Uniwersytetu Medycznego.

Introduction: Radiotherapy is an effective, modern method of treating malignant neoplasms of head and neck and also intracranial tumours. Technological development and computerization of equipment used in radiotherapy enabled introduction of modern methods of treatment allowing decrease the risk of postradiation complications but not eliminating them completely. Postradiant necrosis of temporal bone that is osteoradionecrosis (ORN) is a quite well known complication of radiotherapy of head and neck tumours. Read More

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http://linkinghub.elsevier.com/retrieve/pii/S003066571170714
Publisher Site
http://dx.doi.org/10.1016/S0030-6657(11)70714-4DOI Listing
September 2011
4 Reads

[Necrotizing (malignant) external otitis].

Authors:
V M Bobrov

Vestn Otorinolaringol 2011 (3):71-2

Five cases of necrotizing (malignant) external otitis were diagnosed during 25 years (from 1984 to 2009). All the patients aged from 60 to 80 years presented with diabetes mellitus. Blue pus bacilli were isolated from the ear canal. Read More

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September 2011
2 Reads

Erosive external otitis: a novel distinct clinical entity of the external auditory canal in nonimmunosuppressed individuals.

Otol Neurotol 2010 Dec;31(9):1409-11

Division of Head and Neck Surgery, University of California, San Diego, San Diego, California 92093-0647, USA.

Objective: We introduce erosive external otitis (EEO) as a novel erosive process of the external auditory canal in the absence of diabetes or immune suppression.

Study Design: Case series and literature review.

Setting: Tertiary referral center. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364102PMC
December 2010
15 Reads