186 results match your criteria External Ear Malignant External Otitis


An emergency medicine-focused review of malignant otitis externa.

Am J Emerg Med 2020 Apr 29. Epub 2020 Apr 29.

Brooke Army Medical Center, Department of Emergency Medicine, 3841 Roger Brooke Dr, Fort Sam Houston, TX 78234, United States.

Introduction: Malignant otitis externa (MOE) is a progressive infection of the external auditory canal (EAC). This disease is rare but has severe morbidity and mortality.

Objective: This narrative review provides an overview of malignant otitis externa for emergency clinicians. Read More

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http://dx.doi.org/10.1016/j.ajem.2020.04.083DOI Listing

Malignant Otitis Externa: Causes for Various Treatment Responses.

J Int Adv Otol 2020 Apr;16(1):98-103

Clinic of Otorhinolaryngology and Maxillofacial Surgery, Clinical Center of Serbia, Belgrade, Serbia.

Objectives: Malignant (necrotizing) otitis externa (MOE) is an aggressive form of skin inflammation of the external ear with a tendency to spread infection to the temporal bone. The study aimed to evaluate a causal relationship between treatment responses and clinical features in patients with MOE.

Materials And Methods: In a retrospective, descriptive section study, the database was analyzed between January 2008 and December 2018 in our department, all patients with diagnosed MOE were identified. Read More

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http://dx.doi.org/10.5152/iao.2020.7709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7224427PMC

Surgery for necrotizing otitis externa-indications and surgical findings.

Eur Arch Otorhinolaryngol 2020 May 12;277(5):1327-1334. Epub 2020 Feb 12.

Department of Otolaryngology-Head and Neck Surgery, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Yitzhak I. Rager Blvd 151, 84101, Beer-Sheva, Israel.

Purpose: Treatment for necrotizing otitis externa (NOE) includes long term antibiotic and surgery in selected cases. Indications and extent of surgery, however, are still not defined. The aims of this study were: (1) present our experience in surgery for NOE (2) compare high-resolution computer tomography and perioperative findings (3) suggest recommendations for indications and extent of surgery. Read More

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http://dx.doi.org/10.1007/s00405-020-05842-xDOI Listing

Thirty-Day Readmission and Prolonged Length of Stay in Malignant Otitis Externa.

Laryngoscope 2019 Nov 22. Epub 2019 Nov 22.

Department of Otolaryngology-Head and Neck Surgery, Icahn School of Medicine at Mount Sinai, New York, New York, U.S.A.

Objectives: To determine independent risk factors for 30-day readmission, prolonged length of stay (PLOS), and discharge to a rehabilitation facility for those with malignant otitis externa.

Methods: Retrospective cohort study of patients hospitalized with malignant otitis externa (International Classification of Diseases, 9th edition, code 380.14) in the Nationwide Readmissions Database (2013-2014). Read More

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http://dx.doi.org/10.1002/lary.28409DOI Listing
November 2019

A retrospective review of 14 cases of malignant otitis externa.

J Otol 2019 Jun 8;14(2):63-66. Epub 2019 Jan 8.

Department of Otorhinolaryngology, K.S.Hegde Medical Academy, Nitte(deemed to be University), Mangalore, Karnataka, India.

Background: Malignant otitis externa is an inflammatory condition of the external ear which has the propensity to spread to the skull base. It can be a difficult entity to treat as clinical presentation varies and response to treatment differs between patients. We reviewed cases of malignant otitis externa in our setup to document the epidemiology and outcome of management. Read More

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http://dx.doi.org/10.1016/j.joto.2019.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6570638PMC
June 2019
13 Reads

Malignant (necrotizing) externa otitis: the experience of a single hyperbaric centre.

Eur Arch Otorhinolaryngol 2019 Jul 4;276(7):1881-1887. Epub 2019 Jun 4.

Centro de Medicina Subaquática e Hiperbárica de Lisboa, Lisbon, Portugal.

Introduction: Malignant otitis externa (MOE) is a potentially life-threatening infection of the soft tissues of the external ear, quickly spreading to involve the periosteum and bone of the skull base. Treatment includes antibiotics and eventually surgery. Hyperbaric oxygen treatment (HBOT) has been proposed as an adjunctive therapy. Read More

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http://dx.doi.org/10.1007/s00405-019-05396-7DOI Listing
July 2019
14 Reads

Otitis Externa.

Dtsch Arztebl Int 2019 03;116(13):224-234

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Leipzig; Department of Pediatrics, University Hospital Carl Gustav Carus Dresden, TU Dresden; Institute of General Practice, Technical University of Munich; HNO-Praxis Lundershausen, Erfurt.

Background: Otitis externa has a lifetime prevalence of 10% and can arise in acute, chronic, and necrotizing forms.

Methods: This review is based on publications retrieved by a selective search of the pertinent literature.

Results: The treatment of acute otitis media consists of anal- gesia, cleansing of the external auditory canal, and the appli- cation of antiseptic and antimicrobial agents. Read More

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http://dx.doi.org/10.3238/arztebl.2019.0224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522672PMC
March 2019
11 Reads

[Atypical skull base osteomyelitis suspected of spreading inflammation from the ear canal with unilateral multiple cranial neuropathy and cerebral infarctions].

Rinsho Shinkeigaku 2019 Apr 30;59(4):205-210. Epub 2019 Mar 30.

Department of Neurology, Japan Community Healthcare Organization Kyushu Hospital.

A 76-year-old man, who had undergone surgery for esophageal cancer in 2010, presented to our hospital in April 2017 complaining of prolonged slight fever, loss of appetite, and dysphagia. Initial evaluation revealed a paralyzed left vocal cord, slight muscle weakness of the extremities, left facial paralysis, hoarseness, left sternocleidomastoid and trapezius muscle weakness, tongue deviation to the left, and left hypacusia-suggesting a diagnosis of Garcin's syndrome. Laboratory tests revealed increased white blood cells and C-reactive protein. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001258DOI Listing
April 2019
23 Reads

The Impact of using the term "Diabetic Ear" for the patients with Skull Base Osteomyelitis.

J Family Community Med 2019 Jan-Apr;26(1):23-29

Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Imam Abdulrahman Bin Faisal University, KFUH, Al-Khobar, Saudi Arabia.

Background: Diabetes and ear disease are some of the most widespread health concerns. The focus here is on the impact of using the term "Diabetic Ear" for patients with skull base osteomyelitis (SBM) in the context of malignant otitis externa (MOE). The aim of this study was to discover the awareness of general practitioners (GPs), residents, specialists, and consultants at Primary Health Care Centers about necrotizing otitis externa (NOE), also known previously as malignant external otitis (MOE), assess their deficiencies and provide solutions; also assist them for the early detection and possible prevention of diabetes- related ear diseases and their complications. Read More

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http://dx.doi.org/10.4103/jfcm.JFCM_187_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335838PMC
January 2019
30 Reads

FDG-PET/CT for diagnosis and follow-up of necrotizing (malignant) external otitis.

Laryngoscope 2019 04 14;129(4):961-966. Epub 2018 Dec 14.

Department of Otolaryngology-Head and Neck Surgery, Petach Tikva, Israel.

Objective: Imaging is important for the diagnosis and follow-up of necrotizing external otitis (NEO). The best imaging modality is controversy. To suggest 2-deoxy-2-[fluorine-18] fluoro-D-glucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) as an alternative to technetium-99m and gallium-67 scans for diagnosis and assessment of response to treatment for patients with NEO. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.27526
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http://dx.doi.org/10.1002/lary.27526DOI Listing
April 2019
24 Reads

The Role of Surgical Debridement in Cases of Refractory Malignant Otitis Externa.

Indian J Otolaryngol Head Neck Surg 2018 Dec 18;70(4):549-554. Epub 2018 Jun 18.

Sri Guru Ram Das Institute of Health Sciences and Research Amritsar, 27-C; Sant Avenue, The Mall, Amritsar, 143001 India.

Malignant Otitis externa is a necrotizing condition of external ear involving causing the osteomyelitis of the bone and surrounding soft tissue leading to multiple cranial nerve palsies. Though most patients respond to oral ciprofloxacin but due to emerging resistance cases of refractory malignant otitis externa which are unresponsive to antibiotic therapy for at least 6 weeks are being encountered lately. A study of 20 patients of refractory malignant otitis Externa was conducted at a tertiary care centre in north India; 10 patients were randomly allotted in group A and group B each. Read More

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http://dx.doi.org/10.1007/s12070-018-1426-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224839PMC
December 2018
23 Reads

Diagnosis and treatment of necrotising otitis externa and diabetic foot osteomyelitis - similarities and differences.

J Laryngol Otol 2018 Sep 28;132(9):775-779. Epub 2018 Aug 28.

Department of Otolaryngology - Head and Neck Surgery,Soroka University Medical Center and Faculty of Health Sciences, Ben-Gurion University in the Negev,Beer-Sheva,Israel.

Objective: Necrotising otitis externa is a severe inflammatory process affecting soft tissue and bone, mostly in diabetic patients. Diabetic patients are also at risk of diabetic foot osteomyelitis, another inflammatory condition involving soft tissue and bone. This review aimed to describe the similarities and differences of these entities in an attempt to further advance the management of necrotising otitis externa. Read More

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http://dx.doi.org/10.1017/S002221511800138XDOI Listing
September 2018
24 Reads

Malignant external otitis following radiotherapy for oral cancer: A case report.

Medicine (Baltimore) 2018 May;97(21):e10898

Department of Oral and Maxillofacial Surgery, School of Dental Medicine, Tsurumi University, Yokohama, Japan.

Rationale: Although an ototoxicity is well-known as adverse event of the radiotherapy, it is not widely known that immunosuppressed patients who underwent radiotherapy in head and neck region have risk of malignant external otitis.

Patient Concerns: A 68-year-old man with diabetes, who had been diagnosed as intraosseous squamous cell carcinoma of the right mandible, underwent surgical resection. He received a total of 60 Gy/30Fr postoperative radiation. Read More

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http://dx.doi.org/10.1097/MD.0000000000010898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392893PMC
May 2018
10 Reads

[The tumors of the ear].

Presse Med 2017 Nov 31;46(11):1079-1088. Epub 2017 Oct 31.

Hôpital Robert-Debré, departement d'oto-rhino-laryngologie, 51100 Reims, France; Université de Reims Champagne-Ardenne, faculté de médecine, 51100 Reims, France.

Any cutaneous lesion of the outer ear must be managed jointly by a dermatologist and an ENT, regardless of the age of the patient. The presence of a malignant cutaneous carcinoma (Squamous cell carcinoma or melanoma) of the pavilion requires a minimum extension assessment by a cervical ultrasound, CT-scan and MRI will be prescribed according to the degree of infiltration and the presence of clinics signs (lymphadenopathy, facial paralysis, cognitive impairment). A polyp of the external auditory meatus must be systematically biopsied in consultation and, if necessary, in the operating room with fresh anatomopathological analysis. Read More

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http://dx.doi.org/10.1016/j.lpm.2017.09.016DOI Listing
November 2017
2 Reads

The treatment of pseudoaneurysms with flow diverters after malignant otitis externa.

Interv Neuroradiol 2017 Dec 9;23(6):609-613. Epub 2017 Oct 9.

4 Department of Radiology, Faculty of Medicine, Albert Szent-Györgyi Clinical Center, University of Szeged, Szeged, Hungary.

Background We report a case of bilateral malignant otitis externa complicated with bilateral petrous internal carotid artery pseudoaneurysms and their successful treatment with a flow diverter. Case report A 68-year-old woman with serious complications of type II diabetes mellitus had malignant otitis externa on the right side. She was treated with combined antibiotic therapy and underwent mastoidectomy for mastoiditis. Read More

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http://dx.doi.org/10.1177/1591019917729804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5814079PMC
December 2017
18 Reads

[External auditory canal cholesteatoma].

Pan Afr Med J 2016 27;24:269. Epub 2016 Jul 27.

Service d'Oto-rhino-laryngologie et Chirurgie Cervico-Faciale, CHU Mohammed VI, Oujda, Maroc.

External auditory canal cholesteatoma is defined as an accumulation of keratin leading to osteolytic bony erosion. It is a rare or underdiagnosed otologic entity. Our study aims to illustrate one case of external auditory canal cholesteatoma. Read More

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http://dx.doi.org/10.11604/pamj.2016.24.269.5977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267907PMC
March 2017
14 Reads

Invasive keratinizing squamous cell carcinoma of the left external auricular canal and the middle ear - case report.

Rom J Morphol Embryol 2017 ;58(4):1519-1524

Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, "Titu Maiorescu" University, Bucharest, Romania; Department of Anatomy, Faculty of Dental Medicine, "Ovidius" University of Constanta, Romania;

The rather low incidence of auricular neoplasms irrespective of localization is likely to cause confusion of diagnosis with the more frequent benign ear pathology. Because of this, the elapsed time until confirmation of the diagnosis facilitates the evolution of the disease to the detriment of the patient's health. The diagnosis of an ear neoplasm can hide under the ordinary appearance of external otitis, chronic otorrhea or episodes of various types of ear pain. Read More

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September 2018
4 Reads

Propionibacterium skull base osteomyelitis complicated by internal carotid artery pseudoaneurysm.

Laryngoscope 2017 10 15;127(10):2337-2339. Epub 2016 Nov 15.

Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, U.S.A.

The microbiology of skull base osteomyelitis (SBO) is evolving. We present here the first case of SBO caused by Propionibacterium acnes leading to the development of a pseudoaneurysm of the internal carotid artery. Otolaryngologists should recognize this pathogen as a potential cause of invasive temporal bone infection to optimize prompt diagnosis and treatment. Read More

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http://doi.wiley.com/10.1002/lary.26412
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http://dx.doi.org/10.1002/lary.26412DOI Listing
October 2017
6 Reads

Scedosporium apiospermum: a rare cause of malignant otitis externa.

BMJ Case Rep 2016 Sep 9;2016. Epub 2016 Sep 9.

Department of ENT, South Devon NHS Foundation Trust, Torquay, Devon, UK.

A 79-year-old man, with a history of well-controlled diabetes mellitus, presented with left-sided otalgia. With an initial diagnosis of simple otitis externa, he was discharged on topical drops. He represented 2 months later with worsening otalgia and discharge. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2016-21701
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http://dx.doi.org/10.1136/bcr-2016-217015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020719PMC
September 2016
5 Reads

Malignant external otitis: Factors predicting patient outcomes.

Am J Otolaryngol 2016 Sep-Oct;37(5):425-30. Epub 2016 May 6.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Otolaryngology-Head and Neck Surgery, Meir Medical Center, Kfar Saba, Israel. Electronic address:

Objective: Malignant external otitis (MEO) is an aggressive infection, primarily affecting elderly diabetic patients. It begins in the external ear canal and spreads to adjacent structures. This study investigated the clinical characteristics of patients diagnosed and treated for MEO and analyzed factors affecting patient outcomes. Read More

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http://dx.doi.org/10.1016/j.amjoto.2016.04.005DOI Listing
March 2017
7 Reads

Malignant external otitis in Spain.

Acta Otorrinolaringol Esp 2017 Jan - Feb;68(1):23-28. Epub 2016 May 27.

Servicio de Otorrinolaringología Hospital Universitario de La Ribera, Alzira, Valencia, España.

Introduction: Malignant external otitis is a necrotizing infection, which extends from the squamous epithelium of the ear canal to the adjacent tissue. The objective of the study was to investigate its incidence and other epidemiological data in Spain, reporting the largest case series to date.

Methods: A descriptive, retrospective study of the Spanish population was carried out using the minimum basic data set (MBDS) based on data of patients admitted to hospitals in the 2008-2013 period. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00016519163001
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http://dx.doi.org/10.1016/j.otorri.2016.02.010DOI Listing
February 2018
3 Reads

Malignant Otitis Externa and Stroke.

Eur J Case Rep Intern Med 2016 14;3(4):000387. Epub 2016 Apr 14.

Department of Internal Medicine, Hospital de Egas Moniz, Lisboa, Portugal.

Malignant otitis externa (MOE) is an aggressive but benign entity which evolves into skull base osteomyelitis. An 81-year-old female patient was admitted for left hemiparesis and homonymous hemianopia. She complained of headache radiating to the right cervical area. Read More

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http://dx.doi.org/10.12890/2016_000387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346865PMC
April 2016
4 Reads

Hypoglossal paresis as the only complication of malignant otitis externa.

B-ENT 2015 ;11(3):235-8

Background: Ipsilateral hypoglossal nerve (XII) paresis has never been reported as the first and only complication of malignant otitis external (MOE).

Case Report: A 73-year-old diabetic male with persistent left temporomandibular joint ache and ear fullness was admitted with the diagnosis of MOE. He received intravenous ciprofloxacin for 14 days and then continued with oral administration (per os). Read More

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January 2016
6 Reads

Temporomandibular joint disorder from skull-base osteomyelitis: a case report.

Maxillofac Plast Reconstr Surg 2015 Dec 31;37(1):39. Epub 2015 Oct 31.

Department of Oral and Maxillofacial surgery, Dong-a University Hospital, Daesingongwon-ro 26, Seo-gu, Busan, 602-715 Korea.

Skull-base osteomyelitis is a rare disease affecting the medulla of the temporal, sphenoid, and occipital bones. In general, it occurs due to external ear canal infections caused by malignant external otitis. Skull-base osteomyelitis usually affects elderly diabetic patients. Read More

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http://www.jkamprs.com/content/pdf/s40902-015-0041-1.pdf
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http://www.jkamprs.com/content/37/1/39
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http://dx.doi.org/10.1186/s40902-015-0041-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4628617PMC
December 2015
5 Reads

Radiology of external ear: indications, normal anatomy, and pathological processes.

Radiologia 2016 May-Jun;58(3):189-98. Epub 2015 Oct 12.

Área Clínica de Imagen Médica, Hospital Universitario y Politécnico La Fe, Valencia, España.

The external ear is accessible to direct examination; the clinical history and otoscopy are sufficient to diagnose and treat most diseases of the external ear. We aim to describe the normal anatomy of the external ear, specify the indications for imaging tests, and review the clinical and radiological manifestations of the most common diseases affecting the external ear. We classify these diseases according to their origin into congenital, inflammatory, infectious, or traumatic disease or benign bone tumors or malignant tumors. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00338338150015
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http://dx.doi.org/10.1016/j.rx.2015.08.003DOI Listing
November 2017
6 Reads

Malignant otitis externa in a healthy non-diabetic patient.

Eur Arch Otorhinolaryngol 2016 Aug 2;273(8):2261-5. Epub 2015 Aug 2.

Department of Otolaryngology-Head and Neck Surgery, Nanfang Hospital, Southern Medical University, 1838 Guangzhou Avenue North, Guangzhou, 510515, China.

A healthy 60-year-old male was initially treated for external otitis, and subsequently received multiple surgeries including abscess drainage, temporal bone debridement, canaloplasty of the external auditory meatus, and fistula excision and was treated with numerous antibiotics at another hospital over a 1-year period. He was seen at our hospital on February 14, 2014 with a complaint of a non-healing wound behind the left ear and drainage of purulent fluid. He had no history of diabetes mellitus or compromised immune function. Read More

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http://dx.doi.org/10.1007/s00405-015-3738-yDOI Listing
August 2016
16 Reads

Malignant Otitis Externa - A Retrospective Study of 15 Patients Treated in a Tertiary Healthcare Center.

J Int Adv Otol 2015 Apr;11(1):72-6

Department of Otorhinolaryngology, K S Hegde Medical Academy, Karnataka, India.

Objective: Malignant otitis externa (MOE) is an uncommon but potentially fatal disease of the external auditory canal. The study aimed at evaluating the demographic profile, coexisting disabilities, clinical presentations, and management of MOE.

Materials And Methods: This is a retrospective study of patients with MOE who were treated at the Otorhinolaryngology Department of our institution. Read More

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http://dx.doi.org/10.5152/iao.2015.430DOI Listing
April 2015
33 Reads

Malignant otitis externa.

Ear Nose Throat J 2015 Apr-May;94(4-5):136-8

Department of Otolaryngology-Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA.

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November 2016
10 Reads

Cholesteatoma and osteoradionecrosis after radio­therapy of the temporal bone: Surgical aspects.

Rev Laryngol Otol Rhinol (Bord) 2015;136(4):163-5

Introduction: The treatment for head and neck cancer with radiotherapy can cause different alterations of the auditory system. We report two cases of chronic otitis of the external and middle ear secondary to osteoradionecrosis of the temporal bone. This article aims to report the experience of the surgical approach in such condition. Read More

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March 2018
2 Reads

Squamous cell carcinoma of the external auditory canal in a patient with non-resolving ear discharge.

Malays Fam Physician 2015 31;10(2):52-4. Epub 2015 Aug 31.

Othman bin Abdullah Department of Pathology, Hospital Sultan Abdul Halim, Kedah, Malaysia.

Discharging ear is a common symptom in the primary care and private general clinics. Most of the cases are treated with the antibiotic ear drops for otitis externa or otitis media. However, despite an adequate standard therapy, a malignant tumour can also be present with non-specific symptom such as ear discharge, especially in the case of persistent ear discharge. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4826582PMC
April 2016
4 Reads

Central skull base osteomyelitis: new insights and implications for diagnosis and treatment.

Eur Arch Otorhinolaryngol 2015 May 9;272(5):1269-76. Epub 2014 Nov 9.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Freiburg, Killianstrasse 5, 79106, Freiburg, Germany.

Central skull base osteomyelitis (SBO) is a life-threatening disease originating from ear and from sinonasal infections. The intention of this study was to evaluate contemporary trends in etiology, diagnosis, management, and outcome of SBO and to draw the clinician's attention on this probably underestimated disease. Over a 6-year period we performed this systematic study in an academic quaternary medical care and skull base center including 20 patients (mean age 63. Read More

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http://link.springer.com/content/pdf/10.1007/s00405-014-3390
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http://link.springer.com/10.1007/s00405-014-3390-y
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http://dx.doi.org/10.1007/s00405-014-3390-yDOI Listing
May 2015
21 Reads

[Ear diseases and diabetes mellitus].

HNO 2014 Nov;62(11):823-32

Klinik für Hals-Nasen-Ohrenheilkunde, Kopf- und Halschirurgie, Plastische Operationen, Krankenhaus Martha-Maria Halle-Dölau, Röntgenstr. 1, 06120, Halle (Saale), Deutschland,

In the literature there is very little information about the importance of diabetes mellitus for ear diseases. Therefore, this article gives an overview about contact points between endocrinological and otological problems in patients with diseases of the ear and pre-existing diabetes mellitus. In particular the focus is on the impact of diabetes mellitus on patients with external otitis, malignant external otitis, otitis media, sudden sensorineural hearing loss and slowly progressive hearing loss. Read More

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http://dx.doi.org/10.1007/s00106-014-2902-9DOI Listing
November 2014
9 Reads

Osteomyelitis of the temporal bone: terminology, diagnosis, and management.

J Neurol Surg B Skull Base 2014 Oct 26;75(5):324-31. Epub 2014 Jun 26.

Department of Otolaryngology - Head & Neck Surgery, Kasturba Medical College, Mangalore (Manipal University), Mangalore, Karnataka, India.

Objectives To review the terminology, clinical features, and management of temporal bone osteomyelitis. Design and Setting Prospective study in a tertiary care center from 2001 to 2008. Participants Twenty patients visiting the outpatient department diagnosed with osteomyelitis of the temporal bone. Read More

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http://dx.doi.org/10.1055/s-0034-1372468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176546PMC
October 2014
29 Reads
3 Citations

Diagnosis and surgical treatment of a malignant trichoepithelioma of the ear canal in a pet rabbit (Oryctolagus cuniculus).

J Am Vet Med Assoc 2014 Jul;245(2):227-31

Departments of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706.

Case Description: A 10-year-old spayed female Holland Lop-mix pet rabbit (Oryctolagus cuniculus) was evaluated because of purulent-hemorrhagic discharge from the right ear canal and a suspected mass within that ear canal.

Clinical Findings: Results of contrast-enhanced CT, video otoscopy, and histologic examination of endoscopic tissue biopsy samples indicated severe otitis media and externa and a benign trichoepithelioma of the right ear canal.

Treatment And Outcome: Total ear canal ablation and lateral bulla osteotomy were performed. Read More

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http://dx.doi.org/10.2460/javma.245.2.227DOI Listing
July 2014
40 Reads

B-cell malignant lymphoma presenting as otitis media and mastoiditis associated with sinus thrombosis.

Case Rep Neurol 2014 May 15;6(2):161-5. Epub 2014 May 15.

Department of Neurosurgery, Aomori Prefectural Central Hospital, Aomori, Hirosaki, Japan.

Cerebral venous thrombosis as a manifestation of paraneoplastic angitis and otitis media, revealing non-Hodgkin B-cell lymphoma (NHBL), is extremely rare. A 57-year-old woman presented with headache, auditory disturbance and recalcitrant otitis media. Magnetic resonance imaging showed brain edema in the temporal lobe and transverse sinus thrombosis. Read More

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https://www.karger.com/Article/FullText/362114
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http://dx.doi.org/10.1159/000362114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049015PMC
May 2014
9 Reads

Technetium-99m (⁹⁹mTc)-labelled sulesomab in the management of malignant external otitis: is there any role?

Eur Arch Otorhinolaryngol 2015 Jun 18;272(6):1377-82. Epub 2014 Feb 18.

Department of Otorhinolaryngology, University of Messina, Messina, Italy,

We report two cases of malignant external otitis (MEO) evaluated with Technetium-99m((99m)Tc)-labelled sulesomab. Two patients affected by MEO are presented, together with a literature review. Both patients were studied with clinical examination, ear discharge culture, radiological imaging, blood exams, (99m)Tc Sulesomab, and treated with antibiotic therapy. Read More

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http://dx.doi.org/10.1007/s00405-014-2938-1DOI Listing
June 2015
3 Reads

Survival outcomes of patients with temporal bone squamous cell carcinoma with different invasion patterns.

Head Neck 2015 Feb 12;37(2):188-96. Epub 2014 Feb 12.

Department of Otology and Skull Base Surgery, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China.

Background: The correlation between the survival rate and various invasion patterns of patients with temporal bone squamous cell carcinoma (SCC) is unclear. This study was performed to compare the survival outcomes of these patients to disclose the correlation.

Methods: The cases of 39 patients with temporal bone SCC who underwent surgery between January 2004 and December 2012 were reviewed. Read More

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http://doi.wiley.com/10.1002/hed.23576
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http://dx.doi.org/10.1002/hed.23576DOI Listing
February 2015
58 Reads

Synchronous malignant otitis externa and squamous cell carcinoma of the external auditory canal.

Case Rep Otolaryngol 2013 30;2013:837169. Epub 2013 Sep 30.

Department of Otolaryngology Head and Neck Surgery, Nepean Hospital, The University of Sydney, Sydney, NSW 2747, Australia.

Objectives. To discuss the management of a squamous cell carcinoma in the presence of malignant otitis externa. Study Design. Read More

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http://dx.doi.org/10.1155/2013/837169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806128PMC
November 2013
6 Reads

Skull base osteomyelitis following a mastoidectomy.

Auris Nasus Larynx 2013 Dec 8;40(6):584-6. Epub 2013 Feb 8.

Department of Otorhinolaryngology-Head & Neck Surgery, College of Medicine, Hallym University, Seoul, South Korea.

Skull base osteomyelitis is a rare but life-threatening condition that is characterized by osteitis of the temporal bone and skull base. Although skull base osteomyelitis is recognized as a rare complication of malignant external otitis or middle ear infection, it may also occur following a mastoidectomy. We present a case of an 81-year-old woman who suffered severe otalgia with normal-looking EAC and tympanic membrane that developed six weeks following a canal wall up mastoidectomy. Read More

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http://dx.doi.org/10.1016/j.anl.2012.12.002DOI Listing
December 2013
9 Reads

Complicated necrotizing otitis externa.

Am J Otolaryngol 2013 Nov-Dec;34(6):706-9. Epub 2013 Aug 5.

University of Missouri-Kansas City School of Medicine, Kansas City, MO, USA. Electronic address:

Necrotizing (malignant) otitis externa (NOE) is a rare and invasive infection originating in the external acoustic meatus seen most commonly in diabetes and other immunocompromised states. After a protracted course, disease can smolder and extend into the mastoid, skull base, dural sinuses, and intracranially. We present a case of NOE complicated by mastoiditis, dural sinus thrombosis, and Bezold's abscess in an uncontrolled diabetic presenting with a prolonged course of facial nerve palsy. Read More

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http://dx.doi.org/10.1016/j.amjoto.2013.07.003DOI Listing
October 2014
15 Reads

A case of orbital apex syndrome in a patient with malignant otitis externa.

J Pak Med Assoc 2013 Feb;63(2):271-3

Sections of Ophthalmology and Otolaryngology, Department of Surgery, Aga Khan University, Karachi.

A rare case of skull base infection with a rapid clinical course leading to visual loss and eventually death in a poorly-controlled diabetic patient is presented. A 37-year-old woman presented with a history of visual loss and painful protrusion of the right eye for the preceding 3 days.This was accompanied by vertigo and right-side facial weakness. Read More

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February 2013
6 Reads

Quantitative measurement of m-RNA levels to assess expression of cyclooxygenase-II, inducible nitric oxide synthase and 12-lipoxygenase genes in middle ear cholesteatoma.

Eur Arch Otorhinolaryngol 2014 Jun 6;271(6):1471-5. Epub 2013 Jul 6.

ENT Department, Gazi University, Ankara, Turkey,

To assess expression of three main inflammatory genes, COX-II, ALOX-12 and i-NOS, quantitatively at transcriptional level in cholesteatoma matrix tissue. Ten patients who have chronic otitis media with primary acquired cholesteatoma were included in this study. Tissue samples obtained from cholesteatoma matrix and external ear canal skin (control tissue). Read More

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http://link.springer.com/content/pdf/10.1007/s00405-013-2614
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http://link.springer.com/10.1007/s00405-013-2614-x
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http://dx.doi.org/10.1007/s00405-013-2614-xDOI Listing
June 2014
22 Reads

Hyperbaric oxygen as an adjuvant treatment for malignant otitis externa.

Cochrane Database Syst Rev 2013 May 31(5):CD004617. Epub 2013 May 31.

Department of Otolaryngology, Norfolk and Norwich University Hospital NHS Trust, Norwich, UK.

Background: Malignant, or necrotising, otitis externa is a potentially fatal infection of the external ear canal and surrounding soft tissue and bone. It may be complicated by involvement of cranial nerves, principally the facial nerves and the contents of the jugular foramen. It is an uncommon condition mainly found in the elderly or in diabetics. Read More

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http://dx.doi.org/10.1002/14651858.CD004617.pub3DOI Listing
May 2013
17 Reads

Bisphosphonate-associated osteonecrosis of the external auditory canal.

J Laryngol Otol 2013 Jul 15;127 Suppl 2:S51-3. Epub 2013 May 15.

Department of Haematology, Adelaide Cancer Centre, Adelaide, South Australia, Australia.

Background: Osteonecrosis is a benign condition characterised by necrotic exposed bone, and is associated with bisphosphonate use. Osteonecrosis of the external auditory canal is rare, with only a few reported cases.

Method: Two case reports of temporal bone osteonecrosis are presented. Read More

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http://dx.doi.org/10.1017/S002221511300100XDOI Listing
July 2013
3 Reads

Necrotizing external otitis: a case series.

B-ENT 2013 ;9(1):61-6

Department of Otolaryngology Head and Neck Surgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Objectives: Necrotizing (malignant) external otitis (NEO) is a life-threatening progressive infection of the external auditory canal, mastoid, and skull base. Here, we review the clinical findings for a series of NEO patients.

Methodology: This case review study includes 18 patients with NEO (males: 11 (61. Read More

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July 2013
4 Reads

[Eustachian orifice malignant melanoma: a case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2013 Feb;27(4):221-2

The patient, a 52 year old male was admitted to the hospital, because of right hearing loss before three months. Six months ago; the patient had the right former group sinusitis and nasal polyps, and had the right former group sinus open and polypectomy operation outside the hospital. The surgery was uneventful and the postoperative dressing was done. Read More

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February 2013
44 Reads

Osteonecrosis of the external auditory canal associated with oral bisphosphonate therapy: case report and literature review.

Otol Neurotol 2013 Feb;34(2):209-13

ENT Department, Olomouc University Hospital and Medical School, Palack] University, Olomouc, Czech Republic.

Objective: To present the first case of a patient with oral bisphosphonates-associated ear canal osteonecrosis (BPECO), review previously published cases, and suggest a definition of BPECO.

Patient: A 79-year-old woman with left otorrhea and earache was treated for otitis externa for 2 months. The examination revealed a deep floor of the left ear canal defect. Read More

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http://dx.doi.org/10.1097/mao.0b013e31827ca34dDOI Listing
February 2013
141 Reads

Pseudomonas and Aspergillus interaction in malignant external otitis: risk of treatment failure.

Acta Otorhinolaryngol Ital 2012 Dec;32(6):416-9

ENT-Ear Surgery Unit, Az. Ospedaliera, via Giustiniani 2, Padua, Italy.

Malignant external otitis (MEO) is a rare infection of the temporal bone primarily affecting elderly patients and diabetics or immunocompromised individuals, which may have dismal prognosis if treatment is not prompt and adequate. Almost 95% of MEO cases reported in the literature are attributed to Pseudomonas aeruginosa, and this pathogen is isolated from aural drainage in > 90% of cases. However, in recent years fungal and polymicrobial temporal bone infections have been reported with increasing frequency. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552534PMC
December 2012
5 Reads

Initial management of necrotizing external otitis: errors to avoid.

Eur Ann Otorhinolaryngol Head Neck Dis 2013 Jun 29;130(3):115-21. Epub 2012 Dec 29.

Groupement de coopération sanitaire, centre Antoine-Lacassagne, institut universitaire de la face et du cou, centre hospitalier universitaire de Nice, 31, avenue de Valombrose, 06107 Nice cedex 2, France.

Objectives: Diagnostic and therapeutic practice guidelines have been established for classical forms of benign otitis externa. However, these guidelines do not include unusual forms of the disease, especially "invasive" otitis externa. No consensual diagnostic flow diagram has been published in the literature, which frequently results in delayed diagnosis and inappropriate primary care management. Read More

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http://dx.doi.org/10.1016/j.anorl.2012.04.011DOI Listing
June 2013
22 Reads

[Bilateral bisphosphonate-associated osteonecrosis of the external ear canal : a rare case].

HNO 2012 Dec;60(12):1127-9

Klinik für Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie/Plastische Operationen, Helios-Klinikum Bad Saarow, Pieskower Str. 33, 15526, Bad Saarow, Deutschland.

Osteonecrosis of the mandible is a well-known and dreaded complication after the administration of bisphosphonates. Only a few cases of bisphosphonate-associated osteonecrosis of the external ear canal have been described. Especially after long-lasting bisphosphonate therapy, for example in patients with multiple myeloma, an ulceration of the floor of the bony external auditory canal should be treated surgically and be distinguished from radioosteonecrosis, malignant external otitis, or carcinoma of the external ear. Read More

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http://dx.doi.org/10.1007/s00106-012-2554-6DOI Listing
December 2012
5 Reads