3,781 results match your criteria Exercise-Induced Asthma


Cough in exercise and athletes.

Pulm Pharmacol Ther 2019 Feb 13. Epub 2019 Feb 13.

Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Canada.

In the general population, particularly in individuals with asthma, cough is a common symptom, often reported after exertion, although regular exercise may be associated with a reduction in the prevalence of cough. In athletes, exercise-induced cough is also a particularly frequent symptom. The main etiologies of cough in athletes are somewhat similar to non-athletes, including asthma/airway hyperresponsiveness, upper airways disorders such as allergic or non-allergic rhinitis, and exercise-induced laryngeal obstruction, although these conditions are more frequently observed in athletes. Read More

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http://dx.doi.org/10.1016/j.pupt.2019.02.003DOI Listing
February 2019

Physiotherapy improves symptoms of exercise-induced laryngeal obstruction in young elite athletes: a case series.

BMJ Open Sport Exerc Med 2019 23;5(1):e000487. Epub 2019 Jan 23.

Department of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.

Objective: A constricted, upper chest breathing pattern and postural dealignments habitually accompany exercise-induced laryngeal obstruction (EILO), but there are few effective treatments for athletes presenting with EILO. This case series was conducted to examine whether physiotherapy based on principles from the Norwegian psychomotor physiotherapy (NPMP) combined with elements of cognitive behavioural therapy can reduce laryngeal distress in athletes with EILO.

Methods: Respiratory distress in four subjects was examined by interview prior to a physiotherapeutic body examination. Read More

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http://dx.doi.org/10.1136/bmjsem-2018-000487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347884PMC
January 2019
1 Read

Ventilatory Demand During Stepping and Running: Implications for Exercise-Induced Bronchoconstriction in Children.

Respir Care 2019 Feb 5. Epub 2019 Feb 5.

Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, São Paulo, Brazil.

Background: Single-step tests have been proposed as simple and inexpensive challenges to diagnose exercise-induced bronchoconstriction (EIB) in the pediatric population. Work performed and the resulting ventilation, however, might be substantially lower in stepping than running. This might decrease the diagnostic yield of step-based challenges. Read More

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http://dx.doi.org/10.4187/respcare.06363DOI Listing
February 2019
1 Read

Asthma and youth soccer: an investigation into the level of asthma awareness and training among youth soccer coaches.

Open Access J Sports Med 2019 15;10:17-31. Epub 2019 Jan 15.

Department of Family Medicine, University of Alberta, Edmonton, AB, Canada,

Purpose: Asthma is the most common chronic disease among children. Exercise-induced bronchoconstriction which is common in asthmatic patients also occurs in individuals with no prior asthma diagnosis. Despite this and the fact that soccer is a high ventilation sport, there are no validated asthma management protocols in place for soccer coaches. Read More

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http://dx.doi.org/10.2147/OAJSM.S182178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339450PMC
January 2019
1 Read

Kounis syndrome induced by oral intake of aspirin: case report and literature review.

Pan Afr Med J 2018 30;30:301. Epub 2018 Aug 30.

Department of Cardiology B, Ibn Sina Hospital, Mohammed V University, Rabat, Morocco.

The Kounis-Zavras syndrome is defined as the coincidental occurrence of acute coronary events and hypersensitivity reactions following an allergic reaction including a mast-cell degranulation of vasospastic mediators. This report describes a case of Kounis-Zavras syndrome in the setting of aspirin-induced asthma also known as Samter-Beer triad combining nasal polyps, asthma, and aspirin allergy leading to vasospasm and myocardial infarction. All physicians should be aware of The Kounis syndrome and always keep that unique clinical entity in mind to recognize it promptly and direct the therapy at suppressing the allergic reaction. Read More

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http://dx.doi.org/10.11604/pamj.2018.30.301.14948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320451PMC
January 2019
1 Read

Dysfunctional Breathing in Children and Adults With Asthma.

Front Pediatr 2018 20;6:406. Epub 2018 Dec 20.

University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom.

Asthma occurs across the life course. Its optimal treatment includes the use of personalized management plans that recognize the importance of co-morbidities including so-called "dysfunctional breathing." Such symptoms can arise as a result of induced laryngeal obstruction (ILO) or alterations in the mechanics of normal breathing called breathing pattern disorders. Read More

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http://dx.doi.org/10.3389/fped.2018.00406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306426PMC
December 2018
1 Read

Inconsistent calculation methodology for the eucapnic voluntary hyperpnoea test affects the diagnosis of exercise-induced bronchoconstriction.

BMJ Open Respir Res 2018 18;5(1):e000358. Epub 2018 Dec 18.

School of Kinesiology, University of British Columbia, Vancouver, Canada.

Introduction: The eucapnic voluntary hyperpnoea (EVH) challenge is used to screen for exercise-induced bronchoconstriction. Several criteria have been proposed to determine the decrease in lung function (fall index, FI) following EVH. We compared three published FI calculation methods to determine if they affect the diagnostic classification. Read More

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http://dx.doi.org/10.1136/bmjresp-2018-000358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307554PMC
December 2018
1 Read

[Prevalence of asthma, allergic rhinitis and atopic dermatitis in school children of the Mexican Bajío region].

Rev Alerg Mex 2018 Oct-Dec;65(4):372-378

Universidad Quetzalcóatl en Irapuato, Guanajuato, México.

Background: The prevalence of allergic diseases markedly varies according to the geographical region.

Objective: To determine the prevalence of asthma, allergic rhinitis and atopic dermatitis in children of six and seven years of age.

Methods: Cross-sectional study that included a sample of almost 15 thousand children in five cities of Mexico. Read More

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http://dx.doi.org/10.29262/ram.v65i4.527DOI Listing
January 2019
4 Reads

Dynamic tonsillar prolapse masquerading as paradoxical vocal fold movement dysfunction.

Int J Pediatr Otorhinolaryngol 2019 Mar 2;118:68-72. Epub 2018 Dec 2.

Division of Pediatric Otolaryngology, UPMC Children's Hospital of Pittsburgh, USA.

Introduction: Paradoxical vocal fold movement dysfunction (PVFMD) is a disorder in which the vocal folds involuntarily adduct during inspiration resulting in stridor, cough, dysphonia and dyspnea. Diagnosis of PVFMD is difficult given the episodic nature of the disorder and the often-normal laryngeal exam in between episodes. Moreover, additional sources of obstruction have been identified as sources of Periodic Occurrence of Laryngeal Obstruction (POLO). Read More

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http://dx.doi.org/10.1016/j.ijporl.2018.11.023DOI Listing
March 2019
1 Read

Asthma prevalence and control levels among Special Olympics athletes, and asthma-related knowledge of their coaches.

J Intellect Disabil Res 2018 Dec 19. Epub 2018 Dec 19.

Faculty of Health Science, University of Ontario Institute of Technology, Oshawa, Ontario, Canada.

Background: The prevalence of asthma among athletes with intellectual disabilities, and the asthma knowledge levels of their coaches, is unknown.

Methods: Special Olympics Canada athletes completed a demographic questionnaire (n = 208). Athletes who identified as having ever or current asthma completed the Asthma Control Questionnaire and the Mini Asthma Quality of Life Questionnaire and were measured for height, weight and lung function (n = 73). Read More

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http://doi.wiley.com/10.1111/jir.12579
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http://dx.doi.org/10.1111/jir.12579DOI Listing
December 2018
6 Reads

Influence of weight loss on pulmonary function and levels of adipokines among asthmatic individuals with obesity: One-year follow-up.

Respir Med 2018 Dec 21;145:48-56. Epub 2018 Oct 21.

Department of Surgery, Faculty of Medical Sciences, University of Campinas, Campinas, São Paulo, Brazil.

Background: Individuals with obesity are more likely to develop asthma, but the exact mechanism is still uncertain and several hypotheses have been raised, such as the release of inflammatory mediators secreted by adipose tissue.

Objective: To assess the effects of weight loss in patients submitted to bariatric surgery on pulmonary and systemic inflammation.

Method: The study evaluated patients undergoing bariatric surgery (Roux-en-Y gastric bypass) with the diagnosis of asthma, except smokers. Read More

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http://dx.doi.org/10.1016/j.rmed.2018.10.017DOI Listing
December 2018
2 Reads

Aetiology of anaphylaxis in patients referred to an immunology clinic in Colombo, Sri Lanka.

Allergy Asthma Clin Immunol 2018 8;14:81. Epub 2018 Nov 8.

3Department of Microbiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Colombo, Sri Lanka.

Background: The aetiology of anaphylaxis differs according to types of foods consumed, fauna and foliage and cultural practices. Although the aetiology of anaphylaxis in Western countries are well known, the causes in South Asian countries have not been reported. We sought to determine the causes of anaphylaxis in patients referred to an immunology clinic in Colombo, Sri Lanka. Read More

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https://aacijournal.biomedcentral.com/articles/10.1186/s1322
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http://dx.doi.org/10.1186/s13223-018-0295-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225671PMC
November 2018
9 Reads

Heating-induced contraction in airways smooth muscle: A possible causative factor of exercise-induced bronchoconstriction.

Authors:
Seham Mustafa

Respir Physiol Neurobiol 2019 Jan 6;259:162-165. Epub 2018 Nov 6.

Department of Biomedical Sciences, College of Nursing, Public Authority for Applied Education & Training, Kuwait. Electronic address:

Asthmatic patients often suffer from bronchoconstriction or asthma following breathing hot air or exposure to exercise due to raises the core body temperature. However, the direct effect of heating airways has not been studied yet. The aim of this study is to investigate the effect of heating on tracheal and bronchiolar smooth muscles. Read More

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http://dx.doi.org/10.1016/j.resp.2018.11.001DOI Listing
January 2019
2 Reads

Exercise-Induced Anaphylaxis: Literature Review and Recent Updates.

Curr Allergy Asthma Rep 2018 Oct 26;18(12):72. Epub 2018 Oct 26.

Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, 60 Fenwood Rd., Building for Transformative Medicine, 5th Floor, Boston, MA, 02115, USA.

Purpose Of Review: This paper will review the pathophysiology, diagnosis, and treatment of exercise-induced anaphylaxis and food-dependent, exercise-induced anaphylaxis with an emphasis on novel studies published in the past several years.

Recent Findings: Exercise-induced anaphylaxis (EIAn) is a clinical syndrome characterized by anaphylaxis during or shortly after physical exertion. The syndrome is broadly grouped into two categories: exercise-induced anaphylaxis and food-dependent, exercise-induced anaphylaxis (FDEIAn). Read More

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http://link.springer.com/10.1007/s11882-018-0830-6
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http://dx.doi.org/10.1007/s11882-018-0830-6DOI Listing
October 2018
12 Reads

[Exercise Testing in Respiratory Medicine - DGP Recommendations].

Pneumologie 2018 Oct 10;72(10):687-731. Epub 2018 Oct 10.

Facharztforum Fürth.

This document replaces the DGP recommendations published in 1998 and 2013. Based on recent studies and a consensus conference, the indications, choice and performance of the adequate exercise testing method and its necessary technical and staffing setting are discussed. Detailed recommendations are provided: for blood gas analysis and right heart catheterization during exercise, walk tests, spiroergometry, and stress echocardiography. Read More

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http://dx.doi.org/10.1055/a-0637-8593DOI Listing
October 2018
3 Reads

Exercise-induced anaphylaxis associated with the use of bee pollen.

Ann Allergy Asthma Immunol 2019 Jan 25;122(1):118-119. Epub 2018 Sep 25.

Cleveland Clinic Foundation, Cleveland, Ohio.

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http://dx.doi.org/10.1016/j.anai.2018.09.461DOI Listing
January 2019
2 Reads

The association between paracetamol use and the risk of asthma, rhinitis and eczema in the Polish population.

Ann Agric Environ Med 2018 Sep 17;25(3):428-432. Epub 2018 Apr 17.

Department of the Prevention of Environmental Hazards and Allergology, Medical University of Warsaw, Warsaw, Poland.

Introduction: A growing number of epidemiological studies suggest that paracetamol, which is commonly used in children, may be a risk factor for asthma, allergic rhinitis, and atopic eczema.

Objective: The aim of this study was to determine and characterize the correlation between paracetamol use and asthma, allergic rhinitis, and atopic eczema symptoms in the Polish population.

Material And Methods: The study is part of the ECAP project involving the use of the ISAAC and ECRHS questionnaires. Read More

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http://dx.doi.org/10.26444/aaem/86336DOI Listing
September 2018
7 Reads

Efficient Use of Simple Exercise-Induced Bronchoconstriction Challenge Testing in Pediatric Exercise-Induced Dyspnea.

Respir Care 2019 Jan 25;64(1):71-76. Epub 2018 Sep 25.

Department of Pediatrics, Division of Pulmonology, Akron Children's Hospital, Akron, Ohio.

Background: A simple exercise test to evaluate for exercise-induced bronchoconstriction (EIB) is routinely ordered in pediatric patients with exercise-induced dyspnea. However, the utility of this test in establishing the cause of exercise-induced dyspnea is not thoroughly examined in the pediatric population. We sought to assess the efficiency of a simple EIB challenge test in finding the cause of exercise-induced dyspnea in pediatric patients referred to our tertiary center in the last 5 y. Read More

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http://dx.doi.org/10.4187/respcare.06283DOI Listing
January 2019
4 Reads

Identification and molecular characterization of allergenic non-specific lipid-transfer protein from durum wheat (Triticum turgidum).

Clin Exp Allergy 2019 Jan 7;49(1):120-129. Epub 2018 Oct 7.

Molecular Allergology, Paul-Ehrlich-Institut, Federal Institute for Vaccines and Biomedicines, Langen, Germany.

Background: Common wheat (Triticum aestivum) and durum wheat (T. turgidum) are both involved in Baker's asthma (BA) and food allergy (FA) including wheat-dependent exercise-induced asthma (WDEIA). However, allergens in durum wheat have not been described, and the over-expression of T. Read More

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http://doi.wiley.com/10.1111/cea.13271
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http://dx.doi.org/10.1111/cea.13271DOI Listing
January 2019
19 Reads

Association between quality of life, severity of asthma, sleep disorders and exercise capacity in children with asthma: a cross-sectional study.

Braz J Phys Ther 2019 Jan - Feb;23(1):12-18. Epub 2018 Aug 23.

Postgraduate Studies in Physiotherapy Department, Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil. Electronic address:

Objective: To assess the association between quality of life, asthma severity, sleep disorders and exercise capacity in children with asthma.

Methods: We evaluated 45 children with asthma of both sexes aged between 7 and 12 years, diagnosed by a pediatrician/pulmonologist and classified according to the IV Brazilian Guidelines for Asthma Management: severity (intermittent/mild and moderate/severe) and control (controlled, partially controlled and uncontrolled). Quality of life (QoL), presence of sleep disorders and exercise capacity were respectively assessed using the following instruments: Pediatric Asthma Quality of Life Questionnaire (PAQLQ); Sleep Disturbance Scale for Children (SDSC); and six-minute step test (6MST). Read More

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http://dx.doi.org/10.1016/j.bjpt.2018.08.010DOI Listing
August 2018
3 Reads

Pulmonary function and bronchial reactivity 4 years after the first virus-induced wheezing.

Allergy 2018 Aug 24. Epub 2018 Aug 24.

Department of Paediatrics and Adolescent Medicine, Turku University Hospital and University of Turku, Turku, Finland.

Background: Wheezing illnesses among young children are common and are a risk factor for asthma. However, determinants of childhood bronchial reactivity, a key feature of asthma, are largely unknown. The aim of this study was to determine how patient characteristics during the first severe virus-induced wheezing episode are associated with pulmonary function at preschool age. Read More

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http://doi.wiley.com/10.1111/all.13593
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http://dx.doi.org/10.1111/all.13593DOI Listing
August 2018
9 Reads
6.030 Impact Factor

Genome mapping of seed-borne allergens and immunoresponsive proteins in wheat.

Sci Adv 2018 Aug 17;4(8):eaar8602. Epub 2018 Aug 17.

Norwegian University of Life Sciences, Aas, Norway.

Wheat is an important staple grain for humankind globally because of its end-use quality and nutritional properties and its adaptability to diverse climates. For a small proportion of the population, specific wheat proteins can trigger adverse immune responses and clinical manifestations such as celiac disease, wheat allergy, baker's asthma, and wheat-dependent exercise-induced anaphylaxis (WDEIA). Establishing the content and distribution of the immunostimulatory regions in wheat has been hampered by the complexity of the wheat genome and the lack of complete genome sequence information. Read More

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http://dx.doi.org/10.1126/sciadv.aar8602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097586PMC
August 2018
3 Reads

Exercise-induced bronchoconstriction: prevalence, pathophysiology, patient impact, diagnosis and management.

NPJ Prim Care Respir Med 2018 Aug 14;28(1):31. Epub 2018 Aug 14.

Global Respiratory Franchise, GSK, Middlesex, London, UK.

Exercise-induced bronchoconstriction (EIB) can occur in individuals with and without asthma, and is prevalent among athletes of all levels. In patients with asthma, symptoms of EIB significantly increase the proportion reporting feelings of fearfulness, frustration, isolation, depression and embarrassment compared with those without symptoms. EIB can also prevent patients with asthma from participating in exercise and negatively impact their quality of life. Read More

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http://dx.doi.org/10.1038/s41533-018-0098-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092370PMC
August 2018
2 Reads

[Guidelines for methacholine provocation testing].

Rev Mal Respir 2018 Sep 7;35(7):759-775. Epub 2018 Aug 7.

Antenne médicale de prévention du dopage, EA 3450, service des examens de la fonction respiratoire et de l'aptitude à l'exercice médecine du sport, CHRU de Nancy Brabois, 54500 Vandœuvre-lès-Nancy, France.

Bronchial challenge with the direct bronchoconstrictor agent methacholine is commonly used for the diagnosis of asthma. The "Lung Function" thematic group of the French Pulmonology Society (SPLF) elaborated a series of guidelines for the performance and the interpretation of methacholine challenge testing, based on French clinical guideline methodology. Specifically, guidelines are provided with regard to the choice of judgment criteria, the management of deep inspirations, and the role of methacholine bronchial challenge in the care of asthma, exercise-induced asthma, and professional asthma. Read More

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http://dx.doi.org/10.1016/j.rmr.2018.02.010DOI Listing
September 2018
11 Reads

Small airway function in children with mild to moderate asthmatic symptoms.

Ann Allergy Asthma Immunol 2018 Oct 27;121(4):451-457. Epub 2018 Jul 27.

Pediatric Unit, Department of Allergy, Skin and Allergy Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: Clinical significance of small airway obstruction in mild pediatric asthma is unclear.

Objective: To evaluate small airway properties in children with mild to moderate asthmatic symptoms and the association of small airway function with asthma control and exercise-induced bronchoconstriction (EIB).

Methods: Children (5-10 years old) with recurrent wheezing (n = 42) or persistent troublesome cough (n = 16) and healthy controls (n = 19) performed impulse oscillometry (IOS), spirometry, and a multiple-breath nitrogen washout (MBNW) test. Read More

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http://dx.doi.org/10.1016/j.anai.2018.07.026DOI Listing
October 2018
5 Reads

Physiological and Biological Responses to Short-Term Intermittent Hypobaric Hypoxia Exposure: From Sports and Mountain Medicine to New Biomedical Applications.

Front Physiol 2018 9;9:814. Epub 2018 Jul 9.

Exercise Physiology Unit, Department of Physiological Sciences, Faculty of Medicine and Health Sciences, Universitat de Barcelona, L'Hospitalet de Llobregat, Barcelona, Spain.

In recent years, the altitude acclimatization responses elicited by short-term intermittent exposure to hypoxia have been subject to renewed attention. The main goal of short-term intermittent hypobaric hypoxia exposure programs was originally to improve the aerobic capacity of athletes or to accelerate the altitude acclimatization response in alpinists, since such programs induce an increase in erythrocyte mass. Several model programs of intermittent exposure to hypoxia have presented efficiency with respect to this goal, without any of the inconveniences or negative consequences associated with permanent stays at moderate or high altitudes. Read More

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http://dx.doi.org/10.3389/fphys.2018.00814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046402PMC
July 2018
10 Reads
1 Citation

Prevalence of asthma among male 16 to 18-year-old adolescents in the Northern Borders Region of Saudi Arabia.

Electron Physician 2018 Jun 25;10(6):6920-6926. Epub 2018 Jun 25.

Consultant of Public Health, Saudi Board of Family Medicine, Northern Borders, Arar City, Saudi Arabia.

Background: Asthma is a common chronic disease in adolescents, and has led to a significant morbidity and disability. Few studies have estimated the prevalence of asthma in the Northern Borders Region of Saudi Arabia. Only limited data has been available about prevalence of asthma in adolescents' age. Read More

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http://dx.doi.org/10.19082/6920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049974PMC
June 2018
2 Reads

A novel nutritional intervention improves lung function in overweight/obese adolescents with poorly controlled asthma: the Supplemental Nutrition in Asthma Control (SNAC) pilot study.

FASEB J 2018 Jul 19:fj201700338. Epub 2018 Jul 19.

Center for Nutrition and Metabolism, Children's Hospital Oakland Research Institute (CHORI), Oakland, California, USA.

Asthma in the obese is often severe, difficult to treat, and characterized by less eosinophilic inflammation than asthma in the nonobese. Obesity-associated metabolic dysregulation may be a causal factor. We previously reported that a nutrient- and fiber-dense bar [Children's Hospital Oakland Research Institute (CHORI)-bar], which was designed to fill gaps in poor diets, improved metabolism in healthy overweight/obese (OW/OB) adults. Read More

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http://dx.doi.org/10.1096/fj.201700338DOI Listing
July 2018
2 Reads

Meal-exercise challenge and physical activity reduction impact on immunity and inflammation (MERIIT trial).

Contemp Clin Trials Commun 2018 Jun 9;10:177-189. Epub 2018 May 9.

Basic and Clinical Immunology, Department of Pathology, Faculty of Medicine, University of Porto, Portugal.

Background: The effect of a pre-exercise meal as countermeasure to exercise induced immunodepression is poorly known. Also, sedentary behavior is associated with increased cardiometabolic risk but studies on immune changes are lacking. Therefore, we aimed to assess: 1) the impact of a pre-exercise Mediterranean meal (MdM) compared with a fast-food type meal (FFM) on exercise-induced immunological changes and 2) the impact of an induced acute period of sedentary behavior on neuro-immune-endocrine status. Read More

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http://dx.doi.org/10.1016/j.conctc.2018.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042468PMC
June 2018
4 Reads

Lower Airway Disease in the Athletic Horse.

Authors:
Melissa R Mazan

Vet Clin North Am Equine Pract 2018 Aug;34(2):443-460

Department of Clinical Sciences, Tufts University Cummings School of Veterinary Medicine, 200 Westboro Road, North Grafton, MA 01536, USA. Electronic address:

The airways are the first part of the pathway in the oxygen transport chain that is critical to excellent athletic performance, and the lower airways are considered the final gatekeeper before oxygen enters the blood and carbon dioxide exits. Horses are blessed with large airways and lungs that allow them to be superb athletes, but the down side of this largesse on the part of evolution is that unless they are truly elite athletes they may withstand noninfectious disease of the lower respiratory tract for months to years before the owner or trainer notices. The two conditions of the lower respiratory tract that affect the athletic horse during exercise are exercise-induced pulmonary hemorrhage and inflammatory airway disease. Read More

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http://dx.doi.org/10.1016/j.cveq.2018.04.010DOI Listing
August 2018
8 Reads

Anaphylaxis caused by lipid transfer proteins: an unpredictable clinical syndrome.

Allergol Immunopathol (Madr) 2018 Nov - Dec;46(6):565-570. Epub 2018 Jul 5.

Immunoallergy Department, CUF Descobertas Hospital, Lisbon, Portugal.

Introduction: Lipid transfer proteins (LTPs) are panallergens found in many plant foods. They are a common cause of food-induced anaphylaxis (FIA) in adults living in the Mediterranean area. LTPs have also been proposed as a main cause of food-dependent exercise-induced anaphylaxis (FDEIA). Read More

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http://dx.doi.org/10.1016/j.aller.2018.04.002DOI Listing
January 2019
6 Reads

"Exercise induced asthma" is not always asthma.

Respir Med Case Rep 2018 19;24:138-142. Epub 2018 May 19.

Department of Pneumology, University Hospital Basel, Switzerland.

A 25 year old woman was referred to our center for further evaluation of an exercise-induced dyspnea. Moreover, the patient suffered from hoarseness and recurrent sinusitis and otitis. After initially finding nothing suspicious, a spiro-ergometry was performed. Read More

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http://dx.doi.org/10.1016/j.rmcr.2018.05.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010668PMC
May 2018
2 Reads

Efficacy and safety of the combination fluticasone propionate plus salmeterol in asthmatic preschoolers: An observational study.

J Asthma 2018 Jun 29:1-8. Epub 2018 Jun 29.

a Aristotle University of Thessaloniki , Greece, Paediatric Pulmonology Unit, Hippokration Hospital , Thessaloniki , Greece.

Background: Inhaled Corticosteroids (ICS) are the cornerstone of asthma management in pediatric patients. However, in some cases, asthma is not adequately controlled on ICS alone. Long-acting beta-agonists (LABA) are one of the available additional therapies but their use has rarely been studied among children younger than 5 years. Read More

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http://dx.doi.org/10.1080/02770903.2018.1474923DOI Listing
June 2018
6 Reads
1.830 Impact Factor

Thoracoabdominal Asynchrony Contributes to Exercise Limitation in Mild Asthmatic Subjects.

Front Physiol 2018 13;9:719. Epub 2018 Jun 13.

Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, Italy.

This study aimed to better understand how subjects with stable asthma and without exercise-induced bronchoconstriction respond to mild exercise. Breathing pattern, chest wall compartmental and operational volumes, and thoracoabdominal asynchrony were assessed in 11 stable asthmatic subjects and 10 healthy subjects at rest and during exercise in a cycle-ergometer through optoelectronic plethysmography. Dyspnea and sensation of leg effort were assessed through Borg scale. Read More

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http://dx.doi.org/10.3389/fphys.2018.00719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009101PMC
June 2018
2 Reads

Evaluating pulmonary function, aerobic capacity, and pediatric quality of life following a 10-week aerobic exercise training in school-aged asthmatics: a randomized controlled trial.

Patient Prefer Adherence 2018 15;12:1015-1023. Epub 2018 Jun 15.

Department of Physiotherapy, College of Medical and Health Sciences, Ahlia University, Manama, Kingdom of Bahrain.

Background: It has been documented that aerobic exercise may increase pulmonary functions and aerobic capacity, but limited data has evaluated a child's satisfaction and pediatric quality of life (PQoL) with exercise training.

Objectives: This study aimed to investigate the effects of moderate-intensity exercise training on asthmatic school-aged children.

Subjects And Methods: This study included 38 school-aged children with asthma (23 males and 15 females) aged between 8-12 years. Read More

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http://dx.doi.org/10.2147/PPA.S159622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6007206PMC
June 2018
21 Reads

Acute responses to sprint-interval and continuous exercise in adults with and without exercise-induced bronchoconstriction.

J Sports Sci 2019 Jan 20;37(2):212-220. Epub 2018 Jun 20.

a Faculty of Health Sciences , University of Ontario Institute of Technology , Oshawa , ON , Canada.

The purpose was to compare the airway response to sprint interval exercise (SIE) and continuous exercise (CE) in active adults with exercise-induced bronchoconstriction (EIBC), and to compare ventilatory and oxygen delivery responses between adults with and without EIBC. Adults with EIBC (n = 8, 22.3 ± 3. Read More

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http://dx.doi.org/10.1080/02640414.2018.1488520DOI Listing
January 2019
2 Reads

Repurposing drugs as inhaled therapies in asthma.

Adv Drug Deliv Rev 2018 Aug 12;133:19-33. Epub 2018 Jun 12.

Clinical Professor, Central Clinical School, Sydney Medical School, University of Sydney, Sydney, NSW 2006, Australia. Electronic address:

For the first 40 years of the 20th century treatment for asthma occurred in response to an asthma attack. The treatments were given by injection or orally and included the adrenergic agonists adrenalin/epinephrine and ephedrine and a phosphodiesterase inhibitor theophylline. Epinephrine became available as an aerosol in 1930. Read More

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http://dx.doi.org/10.1016/j.addr.2018.06.006DOI Listing
August 2018
20 Reads
15.040 Impact Factor

Data on various allergen specific IgEs and prospective treatments on food-dependent exercise-induced anaphylaxis.

Data Brief 2018 Jun 5;18:1895-1899. Epub 2018 May 5.

Murayama Pediatrics, 3-2-33 Nagayoshi-Nagahara-Higashi Hirano-ku Osaka-shi, 547-0013 Osaka, Japan.

Food-dependent exercise-induced anaphylaxis (FDEIAn) is an anaphylactic reaction induced by physical exercise after ingestion of certain meals. FDEIAn is not very frequent, but recent case reports associated with various meals indicate an upward trend. Here, we report the data of various food specific IgEs and the clinical course of an experience with a patient who exhibited a unique FDEIAn reaction. Read More

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http://dx.doi.org/10.1016/j.dib.2018.04.097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998299PMC
June 2018
18 Reads

Editorial: The Parallel March of Asthma and Allergy in Childhood: A Multi-Perspective Approach.

Front Pediatr 2018 9;6:135. Epub 2018 May 9.

Pediatric Allergy and Pulmonology Units, Hospital Universitario Virgen de la Arrixaca, IMIB-Arrixaca Bio-health Research Institute, University of Murcia, Murcia, Spain.

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http://dx.doi.org/10.3389/fped.2018.00135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5954088PMC
May 2018
13 Reads

Noninvasive ventilation and respiratory physical therapy reduce exercise-induced bronchospasm and pulmonary inflammation in children with asthma: randomized clinical trial.

Ther Adv Respir Dis 2018 Jan-Dec;12:1753466618777723

Nove de Julho University, Rua Vergueiro, 235/249 - Liberdade, São Paulo - SP, Brazil 01504-000.

Background: Asthma is characterized by hyperresponsiveness of the airways, and exercise-induced bronchospasm (EIB) is a symptom that limits a large proportion of asthmatic patients, especially children. Continuous positive airway pressure (CPAP) leads to a reduction in the reactivity of the airways. The aim of this study was to evaluate the effect of outpatient treatment with CPAP and bilevel pressure combined with respiratory physical therapy for children and adolescents with asthma following bronchial hyperresponsiveness caused by an exercise bronchoprovocation test. Read More

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http://dx.doi.org/10.1177/1753466618777723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990882PMC
January 2019
25 Reads

An independent relation of atopic dermatitis to exercise-induced wheezing in asthmatic children.

Allergol Int 2019 Jan 30;68(1):26-32. Epub 2018 May 30.

Department of Allergy, Tokyo Metropolitan Children's Medical Centre, Tokyo, Japan.

Background: Atopic dermatitis (AD) and exercise-induced asthma (EIA) are common in asthmatic children, and exercise is the most common trigger other than infection for acute onset asthma attack in children. We examined whether AD is related to exercise-induced wheezing (EIW), some proxy for EIA.

Methods: Japanese version of the International Study of Asthma and Allergies in Childhood questionnaires were used. Read More

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http://dx.doi.org/10.1016/j.alit.2018.04.013DOI Listing
January 2019
7 Reads

Exhaled nitric oxide and mannitol test to predict exercise-induced bronchoconstriction.

Pediatr Int 2018 Aug;60(8):691-696

Department of Pediatrics, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.

Background: Exercise-induced bronchoconstriction (EIB) is diagnosed via exercise challenge on a treadmill, but such testing requires complex equipment and sufficient health-care resources. The fraction of exhaled nitric oxide (FeNO) test and mannitol bronchial provocation test (BPT) may serve as a surrogate for exercise testing.

Methods: We compared the diagnostic utilities of the FeNO test and mannitol BPT in predicting EIB in asthmatic children. Read More

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http://dx.doi.org/10.1111/ped.13599DOI Listing
August 2018
14 Reads

Hypertrophic effect of inhaled beta -agonist with and without concurrent exercise training: A randomized controlled trial.

Scand J Med Sci Sports 2018 Oct 7;28(10):2114-2122. Epub 2018 Jun 7.

Section of Integrative Physiology, Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark.

Due to a high prevalence of asthma and exercise-induced bronchoconstriction in elite athletes, there is a high use of beta -adrenoceptor agonists (beta -agonists) in the athletic population. While anabolic in rodents, no study has been able to detect hypertrophy in humans after chronic beta -agonist inhalation. We investigated whether inhaled beta -agonist, terbutaline, alters body composition and metabolic rate with and without concurrent exercise training in healthy young men. Read More

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http://doi.wiley.com/10.1111/sms.13221
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http://dx.doi.org/10.1111/sms.13221DOI Listing
October 2018
8 Reads

Exercise-induced laryngeal obstruction in athletes: Contributory factors and treatment implications.

Physiother Theory Pract 2018 May 14:1-12. Epub 2018 May 14.

c Department of Sports medicine , The Norwegian School of Sport Sciences , Oslo , Norway.

Otherwise healthy adolescent athletes presenting with respiratory symptoms consistent with exercise-induced laryngeal obstruction (EILO) are frequently encountered in clinical practice. The symptoms are often incorrectly considered to result from exercise-induced asthma, and may be wrongly treated as such. Given the potential implications for health and performance if EILO is left untreated, a more comprehensive understanding of contributory mechanisms is essential in order to create appropriate treatment procedures. Read More

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https://www.tandfonline.com/doi/full/10.1080/09593985.2018.1
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http://dx.doi.org/10.1080/09593985.2018.1474306DOI Listing
May 2018
6 Reads

Exercise-induced bronchospasm in children and adolescents with allergic rhinitis by treadmill and hyperventilation challenges.

Respir Med 2018 05 3;138:102-106. Epub 2018 Apr 3.

Health Sciences Postgraduate Course, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil; Center for Research in Allergy and Clinical Immunology, Clinical Hospital, Federal University of Pernambuco, Recife, Brazil; Child and Adolescent Health Postgraduate Course, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil.

Background: Respiratory complaints after exercise are common in patients with rhinitis. Exercise-induced bronchospasm (EIB) may be one of the causes.

Objectives: To evaluate EIB prevalence in a group of children and adolescents with allergic rhinitis, to compare the treadmill running (TR) and eucapnic voluntary hyperventilation (EVH) challenge methods as diagnostic tools and to assess the association between respiratory complaints on exercise and EIB. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09546111183010
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http://dx.doi.org/10.1016/j.rmed.2018.04.001DOI Listing
May 2018
5 Reads

Development of a tool predicting severity of allergic reaction during peanut challenge.

Ann Allergy Asthma Immunol 2018 Jul 27;121(1):69-76.e2. Epub 2018 Apr 27.

Sean N. Parker Center for Allergy and Asthma Research, Stanford University, Stanford, California; Department of Medicine, Stanford University School of Medicine, Stanford, California; Department of Pediatrics, Stanford University School of Medicine, Stanford, California. Electronic address:

Background: Reliable prognostic markers for predicting severity of allergic reactions during oral food challenges (OFCs) have not been established.

Objective: To develop a predictive algorithm of a food challenge severity score (CSS) to identify those at higher risk for severe reactions to a standardized peanut OFC.

Methods: Medical history and allergy test results were obtained for 120 peanut allergic participants who underwent double-blind, placebo-controlled food challenges. Read More

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http://dx.doi.org/10.1016/j.anai.2018.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026554PMC
July 2018
12 Reads

Echocardiographic Assessment of Ventricular Function in Young Patients with Asthma.

Arq Bras Cardiol 2018 Mar;110(3):231-239

Faculdade Ciências Médicas - Minas Gerais, Belo Horizonte, MG, Brazil.

Background: Despite significant advances in understanding the pathophysiology and management of asthma, some of systemic effects of asthma are still not well defined.

Objectives: To compare heart function, baseline physical activity level, and functional exercise capacity in young patients with mild-to-moderate asthma and healthy controls.

Methods: Eighteen healthy (12. Read More

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http://dx.doi.org/10.5935/abc.20180052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898772PMC
March 2018
13 Reads

Impact of detecting and treating exercise-induced bronchoconstriction in elite footballers.

ERJ Open Res 2018 Apr 20;4(2). Epub 2018 Apr 20.

School of Sport and Exercise Sciences, University of Kent, Chatham, UK.

Our aim was to evaluate the prevalence of exercise-induced bronchoconstriction (EIB) in elite football players and assess subsequent impact of therapy on airway health and exercise performance. 97 male professional football players completed an airway health assessment with a eucapnic voluntary hyperpnoea (EVH) challenge to diagnose EIB. Players demonstrating a positive result (EVH) were prescribed inhaler therapy depending on severity, including inhaled corticosteroids and inhaled short-acting β-agonists, and underwent repeat assessment after 9 weeks of treatment. Read More

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http://dx.doi.org/10.1183/23120541.00122-2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909043PMC
April 2018
3 Reads

Breathless athlete: exercise-induced laryngeal obstruction.

Br J Sports Med 2018 Sep 18;52(18):1211-1212. Epub 2018 Apr 18.

Department of Respiratory Medicine, Royal Brompton Hospital, London, UK.

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http://dx.doi.org/10.1136/bjsports-2018-099159DOI Listing
September 2018
5 Reads

Variation in the TEK gene is not associated with asthma but with allergic conjunctivitis.

Int J Immunogenet 2018 Jun 18;45(3):102-108. Epub 2018 Apr 18.

Department of Genetics, Cell- and Immunobiology, Semmelweis University, Budapest, Hungary.

The Tie2 receptor is an important player in angiogenesis. The Tie2 mRNA and protein are abundantly expressed in the lungs and the associated pathway also has an important role in the development and function of the eye. Tie2 is encoded by the TEK gene in humans. Read More

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http://doi.wiley.com/10.1111/iji.12365
Publisher Site
http://dx.doi.org/10.1111/iji.12365DOI Listing
June 2018
14 Reads