19,348 results match your criteria Exercise-Induced Asthma


An inducible knockout of Dicer in adult mice does not affect endurance exercise-induced muscle adaptation.

Am J Physiol Cell Physiol 2018 Dec 12. Epub 2018 Dec 12.

Faculty of Health and Sport Sciences, The University of Tokyo, Waseda University, Japan.

The contractile and metabolic properties of adult skeletal muscle change in response to endurance exercise. The mechanisms of transcriptional regulation in exercise-induced skeletal muscle adaptation, including fiber-type switching and mitochondrial biogenesis, have been investigated intensively, whereas the role of microRNA (miRNA)-mediated posttranscriptional gene regulation is less well understood. We used tamoxifen-inducible Dicer1 knockout (iDicer KO) mice to reduce the global expression of miRNAs in adult skeletal muscle and subjected these mice to 2 weeks of voluntary wheel running. Read More

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December 2018

Muscle metaboreflex activation via postexercise ischemia as a tool for teaching cardiovascular physiology for undergraduate students.

Adv Physiol Educ 2019 Mar;43(1):34-41

NeuroV̇ASQ̇, Integrative Physiology Laboratory, Faculty of Physical Education, University of Brasília , Brasília , Brazil.

The cardiovascular responses to exercise are mediated by several interactive neural mechanisms, including central command, arterial baroreflex, and skeletal muscle mechano- and metaboreflex. In humans, muscle metaboreflex activation can be isolated via postexercise ischemia (PEI), which increases sympathetic nerve activity and partially maintains the exercise-induced increase in arterial blood pressure. Here, we describe a practical laboratory class using PEI as a simple and useful technique to teach cardiovascular physiology. Read More

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Rehabilitation following spinal cord injury: how animal models can help our understanding of exercise-induced neuroplasticity.

Neural Regen Res 2019 Mar;14(3):405-412

Institute of Clinical Neuroimmunology, Ludwig-Maximilians Universität München; Munich Cluster of Systems Neurology (SyNergy), Munich, Germany.

Spinal cord injury is a devastating condition that is followed by long and often unsuccessful recovery after trauma. The state of the art approach to manage paralysis and concomitant impairments is rehabilitation, which is the only strategy that has proven to be effective and beneficial for the patients over the last decades. How rehabilitation influences the remodeling of spinal axonal connections in patients is important to understand, in order to better target these changes and define the optimal timing and onset of training. Read More

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The Influence of Oxygen Saturation on the Relationship Between Hemoglobin Mass and VO max.

Sports Med Int Open 2018 Jul 6;2(4):E98-E104. Epub 2018 Sep 6.

Department of Integrative Physiology, University of Colorado Boulder, Boulder, United States.

Hemoglobin mass (tHb) is a key determinant of maximal oxygen uptake (VO max). We examined whether oxyhemoglobin desaturation (ΔS O ) at VO max modifies the relationship between tHb and VO max at moderate altitude (1,625 m). Seventeen female and 16 male competitive, endurance-trained moderate-altitude residents performed two tHb assessments and two graded exercise tests on a cycle ergometer to determine VO max and ΔS O . Read More

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Metabolic and Performance Responses to Sprint Exercise under Hypoxia among Female Athletes.

Sports Med Int Open 2018 Jun 22;2(3):E71-E78. Epub 2018 Aug 22.

Ritsumeikan University, Faculty of Sport and Health Science, Kusatsu, Japan.

The present study determined metabolic and performance responses to repeated sprint exercise under hypoxia among female team-sport athletes. Fifteen female athletes (age, 20.7±0. Read More

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Exercise-related QT interval shortening with a peaked T wave in a boy with MEN 2 syndrome.

J Cardiol Cases 2013 Apr 1;7(4):e93-e96. Epub 2012 Dec 1.

Department of Cardiology, Bayindir Hospital, Ankara, Turkey.

Multiple endocrine neoplasia 2 (MEN 2) is a hereditary syndrome associated with medullary thyroid carcinoma, pheochromocytoma (PCC), and hyperparathyroidism. PCCs in patients with MEN 2 are usually found in the adrenals after the manifestation of medullary thyroid cancer and are commonly bilateral and hormonally active. Unfortunately, a diagnosis of MEN 2 or PCC often is delayed until after the patient has developed an advanced MEN 2-related tumor. Read More

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Sudden cardiac death: Beware of hasty diagnosis!

J Cardiol Cases 2013 Mar 3;7(3):e68-e70. Epub 2012 Dec 3.

Le2i UMR CNRS 5158, Dijon, France.

We report the case of a 21-year-old man admitted to the intensive-care unit after resuscitation from a sudden cardiac death (SCD) while he was playing football. Using a wide range of imaging techniques, we diagnosed a singular association between a hypertrophic cardiomyopathy (HCM) and an abnormal left coronary artery origin from the right coronary artery. Coronary artery anomalies, after HCM, are the second most common cause of SCD during exercise in young athletes, but the association between these 2 diseases is very uncommon. Read More

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Interleukin-10 responses from acute exercise in healthy subjects: A systematic review.

J Cell Physiol 2018 Dec 7. Epub 2018 Dec 7.

Exercise and Immunometabolism Research Group, Postgraduation Program in Movement Sciences, Department of Physical Education, Universidade Estadual Paulista (UNESP), Presidente Prudente, São Paulo, Brazil.

Purpose: Interleukin 10 (IL-10) is a cytokine that plays a critical role with potent anti-inflammatory properties when produced during exercise, limiting host immune response to pathogens and preventing tissue damage. The purpose of this systematic review was to assess the response of IL-10 after acute exercise session in healthy adults.

Methods: Databases of Ovid Medline (1978-2016), CINAHL (1998-2016), EMBASE (2003-2016), SportDiscus (1990-2016), and Web of Science library (1990-2016) were carefully screened. Read More

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December 2018

Effects of short-term endurance exercise on gut microbiota in elderly men.

Physiol Rep 2018 Dec;6(23):e13935

Institute of Advanced Active Aging Research, Tokorozawa, Japan.

Regular exercise reduces the risks for cardiovascular diseases. Although the gut microbiota has been associated with fitness level and cardiometabolic risk factors, the effects of exercise-induced gut microbiota changes in elderly individuals are unclear. This study evaluated whether endurance exercise modulates the gut microbiota in elderly subjects, and whether these changes are associated with host cardiometabolic phenotypes. Read More

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December 2018
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It's Harder to Push, When I Have to Push Hard-Physical Exertion and Fatigue Changes Reasoning and Decision-Making on Hypothetical Moral Dilemmas in Males.

Front Behav Neurosci 2018 23;12:268. Epub 2018 Nov 23.

Department of Psychology, University of Greifswald, Greifswald, Germany.

Despite the prevalence of physical exertion and fatigue during military, firefighting and disaster medicine operations, sports or even daily life, their acute effects on moral reasoning and moral decision-making have never been systematically investigated. To test the effects of physical exertion on moral reasoning and moral decision-making, we administered a moral dilemma task to 32 male participants during a moderate or high intensity cycling intervention. Participants in the high intensity cycling group tended to show more non-utilitarian reasoning and more non-utilitarian decision-making on impersonal but not on personal dilemmas than participants in the moderate intensity cycling group. Read More

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November 2018

Role of Physical Activity in Parkinson's Disease.

Ann Indian Acad Neurol 2018 Oct-Dec;21(4):242-249

Department of Neurology, National Neuroscience Institute, Singapore.

Parkinson's disease (PD) is common, age-dependent neurodegenerative disorder caused by a severe loss of the nigrostriatal dopaminergic neurons. Given the projected increase in the number of people with PD over the coming decades, interventions aimed at minimizing morbidity and improve quality of life are crucial. There is currently no fully proven pharmacological therapy that can modify or slow the disease progression. Read More

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December 2018

Successful medical management and rehabilitation of exercise-induced dorsal scapular luxation in an ultramarathon endurance sled dog with magnetic resonance imaging diagnosis of grade II serratus ventralis strain.

Can Vet J 2018 Dec;59(12):1329-1332

Department of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York, USA (Frye); Department of Veterinary Medicine, University of Alaska Fairbanks, Fairbanks, Alaska, USA (Hansen); Department of Veterinary Biosciences and Diagnostic Imaging, University of Georgia, Athens, Georgia, USA (Gendron); Friendship Surgical Specialists of the Friendship Hospital for Animals, Washington, DC, USA (von Pfeil).

Dorsal displacement of the scapula in dogs is rare and often traumatic. This report describes dorsal luxation of the scapula in a sled dog. This case is unique given the injury was sport-related. Read More

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December 2018

Increasing Wellness Through Physical Activity in Children With Chronic Disease and Disability.

Curr Sports Med Rep 2018 Dec;17(12):425-432

Diploma Sport Medicine McGill University Faculty of Science Montreal, QC CANADA.

Children with chronic medical conditions face many challenges when considering sport participation. Compared with their healthy counterparts, they are often discouraged from physical activity or sports participation because of real or perceived limitations imposed by their condition. Prescribed exercise should be based on the demands of the sport, the effect of the disease on performance, and the potential for exercise-induced acute or chronic worsening of the illness or disability. Read More

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December 2018

Sarcopenia targeting with autophagy mechanism by exercise.

BMB Rep 2018 Dec 11. Epub 2018 Dec 11.

Department of life Science, University of Science and Technology (UST), Daejeon 34113, Korea.

The loss of skeletal muscle, called sarcopenia, is an inevitable event during the aging process, and significantly impacts quality of life. Autophagy is known to reduce muscle atrophy caused by dysfunctional organelles, even though the molecular mechanism remains unclear. Here, we have discuss the current understanding of exercise-induced autophagy activation in skeletal muscle regeneration and remodeling, leading to sarcopenia intervention. Read More

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December 2018

Does vibration benefit delayed-onset muscle soreness?: a meta-analysis and systematic review.

J Int Med Res 2018 Dec 10:300060518814999. Epub 2018 Dec 10.

8 School of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai, P. R. China.

Objective: Delayed-onset muscle soreness (DOMS) is a symptom of exercise-induced muscle injury that is commonly encountered in athletes and fitness enthusiasts. Vibration is being increasingly used to prevent or treat DOMS. We therefore carried out a meta-analysis to evaluate the effectiveness of vibration in patients with DOMS. Read More

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December 2018

Hypothesized mechanisms through which acute exercise influences episodic memory.

Physiol Int 2018 Dec 10:1-13. Epub 2018 Dec 10.

1 Exercise & Memory Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi , Oxford, MS, USA.

Emerging research demonstrates that exercise is favorably associated with several cognitive outcomes, including episodic memory function. The majority of the mechanistic work describing the underlying mechanisms of this effect has focused on chronic exercise engagement. Such mechanisms include, e. Read More

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December 2018

Cerebrovascular Function in the Large Arteries Is Maintained Following Moderate Intensity Exercise.

Front Physiol 2018 21;9:1657. Epub 2018 Nov 21.

Centre for Heart Lung and Vascular Health, School of Health and Exercise Science, University of British Columbia Okanagan, Kelowna, BC, Canada.

Exercise has been shown to induce cerebrovascular adaptations. However, the underlying temporal dynamics are poorly understood, and regional variation in the vascular response to exercise has been observed in the large cerebral arteries. Here, we sought to measure the cerebrovascular effects of a single 20-min session of moderate-intensity exercise in the one hour period immediately following exercise cessation. Read More

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November 2018

French translation and validation of the exercise-induced leg pain Questionnaire.

Disabil Rehabil 2018 Dec 3:1-6. Epub 2018 Dec 3.

c Department of Sport and Rehabilitation Sciences , University of Liège , Liège , Belgium.

Objective: The "Exercise-Induced Leg Pain" questionnaire was developed (in German) for the evaluation of the severity of symptoms and sports ability in individuals with exercise-induced leg pain. The purpose of the present study was to translate and cross-culturally adapt this questionnaire into French and to study the reliability and validity of this French-language version.

Methods: The translation and cross-cultural adaptation of the original "Exercise-Induced Leg Pain" was performed according to established guidelines. Read More

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December 2018
2 Reads

Exercise-induced Illness and Inflammation: Can Immunonutrition and Iron Help?

Int J Sport Nutr Exerc Metab 2018 Dec 3:1-26. Epub 2018 Dec 3.

4 School of Human Sciences, The University of Western Australia, Perth, Australia.

The main focus of this review is illness amongst elite athletes, how and why it occurs, and whether any measures can be taken to combat it or to prevent its onset. In particular, there is particular interest in exercise-induced immunodepression which is a result of the immune system regarding exercise (for example, prolonged, exhaustive exercise) as a challenge to its function. This promotes the inflammatory response. Read More

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December 2018

Amplification of endothelium-dependent vasodilatation in contracting human skeletal muscle: role of K channels.

J Physiol 2018 Dec 1. Epub 2018 Dec 1.

Human Cardiovascular Physiology Laboratory, Department of Health and Exercise Science.

Key Points: In humans, the vasodilatory response to skeletal muscle contraction is mediated in part by activation of inwardly rectifying potassium (K ) channels. Evidence from animal models suggest that K channels serve as electrical amplifiers of endothelium-dependent hyperpolarization (EDH). We found that skeletal muscle contraction amplifies vasodilatation to the endothelium-dependent agonist acetylcholine (ACh), whereas there was no change in the vasodilatory response to sodium nitroprusside, an endothelium-independent nitric oxide donor. Read More

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December 2018
3 Reads

Low-Level Laser Therapy Prevents Treadmill Exercise-Induced Progression of Arthrogenic Joint Contracture Via Attenuation of Inflammation and Fibrosis in Remobilized Rat Knees.

Inflammation 2018 Dec 1. Epub 2018 Dec 1.

Department of Rehabilitation, Faculty of Rehabilitation, Hiroshima International University, Kurose-Gakuendai 555-36, Higashi-Hiroshima, Hiroshima, 739-2695, Japan.

We investigated whether the combination of exercise and anti-inflammatory/anti-fibrotic treatment using low-level laser therapy (LLLT) promotes recovery from joint contracture without arthrogenic contracture progression. Rat knees were immobilized for 3 weeks in a flexed position. After fixator removal, rats were divided into no intervention (RM), daily treadmill walking (WALK), and daily treadmill walking and LLLT (W + L) groups. Read More

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December 2018

A Moving Anecdote: Exercise-Induced Vasovagal Sinus Arrest.

Am J Med 2018 Nov 29. Epub 2018 Nov 29.

Division of Heart Rhythm Services, Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN. Electronic address:

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November 2018

A systematic comparison of exercise training protocols on animal models of cardiovascular capacity.

Life Sci 2018 Dec 2. Epub 2018 Dec 2.

National Engineering Laboratory for Resource Development of Endangered Crude Drugs in Northwest of China/CGDB, Shaanxi Normal University College of Life Sciences, Xi'an 710119, China. Electronic address:

Cardiovascular disease (CVD) is a major global cause of mortality, which has prompted numerous studies seeking to reduce the risk of heart failure and sudden cardiac death. While regular physical activity is known to improve CVD associated morbidity and mortality, the optimal duration, frequency, and intensity of exercise remains unclear. To address this uncertainty, various animal models have been used to study the cardioprotective effects of exercise and related molecular mechanism such as the mice training models significantly decrease size of myocardial infarct by affecting Kir6. Read More

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December 2018
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Impact of Environmental Stressors on Tolerance to Hemorrhage in Humans.

Am J Physiol Regul Integr Comp Physiol 2018 Dec 5. Epub 2018 Dec 5.

Exercise and Nutrition Sciences, University at Buffalo, United States.

Hemorrhage is a leading cause of death in the military and civilian settings and approximately 85% of potentially survivable battlefield deaths are hemorrhage related. Both Soldiers and civilians are exposed to a number of environmental and physiological conditions that have the potential to alter tolerance to a hemorrhagic insult. The objective of this review article is to summarize the known impact of commonly encountered environmental and physiological conditions on hemorrhagic tolerance, primarily in humans. Read More

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December 2018
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Response of Sclerostin and Bone Turnover Markers to High Intensity Interval Exercise in Young Women: Does Impact Matter?

Biomed Res Int 2018 1;2018:4864952. Epub 2018 Nov 1.

Department of Kinesiology, Faculty of Applied Health Sciences, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, Ontario, Canada.

This study examined potential exercise-induced changes in sclerostin and in bone turnover markers in young women following two modes of high intensity interval exercise that involve impact (running) or no-impact (cycling). Healthy, recreationally active, females (n=20; 22.5±2. Read More

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November 2018

Effects of Exercise on the Resting Heart Rate: A Systematic Review and Meta-Analysis of Interventional Studies.

J Clin Med 2018 Dec 1;7(12). Epub 2018 Dec 1.

Paracelsus-Klinik Bremen, In der Vahr 65, D-28329 Bremen, Germany.

Resting heart rate (RHR) is positively related with mortality. Regular exercise causes a reduction in RHR. The aim of the systematic review was to assess whether regular exercise or sports have an impact on the RHR in healthy subjects by taking different types of sports into account. Read More

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December 2018
1 Read

Estrogen receptor alpha signaling maintains immunometabolic function in males and is obligatory for exercise-induced amelioration of nonalcoholic fatty liver.

Am J Physiol Endocrinol Metab 2018 Dec 4. Epub 2018 Dec 4.

University of Missouri, United States.

The role of estrogen receptor alpha (ERα) signaling in immunometabolic function is established in females. However, its necessity in males, while appreciated, requires further study. Accordingly, we first determined whether lower metabolic function in male mice compared to females is related to reduced ERα expression. Read More

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December 2018

Compensation in response to energy deficits induced by exercise or diet.

Obes Rev 2018 Dec;19 Suppl 1:36-46

School of Human Kinetics, Faculty of Health Sciences, University of Ottawa, Ottawa, Canada.

Obesity is an extremely resilient condition. Weight loss is most challenging, and weight recidivism is rampant. There is accumulating evidence highlighting that energy deficits meant to produce increased mobilization of energy stores trigger a number of somewhat persistent adaptations that together increase the drive to eat and decrease energy output. Read More

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December 2018

Guidelines for exercise during normal pregnancy and gestational diabetes: a review of international recommendations.

Hormones (Athens) 2018 Dec 3. Epub 2018 Dec 3.

School of Physical Education and Sports Science, Democritus University of Thrace, 69100, Komotini, Greece.

Objective: Τo summarize and present the main guidelines for exercise during normal pregnancy and pregnancy complicated by gestational diabetes mellitus (GDM).

Methods: Relevant guidelines were retrieved through the electronic databases PubMed (MEDLINE), CENTRAL (Cochrane), and Embase; reference sections of the retrieved publications; proceedings of the main congresses in the field; and websites of relevant organizations published during the years 2000-2018.

Results: All guidelines recommend aerobic training from 60 to 150 min/week, with an upper limit of 30 min/day. Read More

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December 2018
1 Read

Antioxidants Facilitate High-intensity Exercise IL-15 Expression in Skeletal Muscle.

Int J Sports Med 2018 Nov 29. Epub 2018 Nov 29.

Research Institute of Biomedical and Health Sciences (IUIBS), Universidad de Las Palmas de Gran Canaria - Campus de Tafira, Las Palmas de Gran Canaria, Spain.

Interleukin (IL)-15 stimulates mitochondrial biogenesis, fat oxidation, glucose uptake and myogenesis in skeletal muscle. However, the mechanisms by which exercise triggers IL-15 expression remain to be elucidated in humans. This study aimed at determining whether high-intensity exercise and exercise-induced RONS stimulate IL-15/IL-15Rα expression and its signaling pathway (STAT3) in human skeletal muscle. Read More

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November 2018
5 Reads

Menstrual Cycle Phase Does Not Modulate Whole-Body Heat Loss during Exercise in Hot, Dry Conditions.

J Appl Physiol (1985) 2018 Nov 29. Epub 2018 Nov 29.

School of Human Kinetics, University of Ottawa, Canada.

Menstrual cycle phase has long been thought to modulate thermoregulatory function. However, information pertaining to the effects of menstrual phase on time-dependent changes in whole-body dry and evaporative heat exchange during exercise-induced heat stress and the specific heat load at which menstrual phase modulates whole-body heat loss remained unavailable. We therefore used direct calorimetry to continuously assess whole-body dry and evaporative exchange in twelve habitually active, non-endurance trained, eumenorrheic females (21±2 years) within the early-follicular, late-follicular and mid-luteal menstrual phases during three, 30-min bouts of cycling at increasing fixed exercise intensities of 40% (Low), 55% (Moderate) and 70% (High) V̇O, each followed by a 15-min recovery, in hot, dry conditions (40°C, 15% relative humidity). Read More

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November 2018
1 Read

No evidence of direct association between GLUT4 and glycogen in human skeletal muscle.

Physiol Rep 2018 Nov;6(22):e13917

Department of Physiology, The University of Melbourne, Melbourne, Australia.

Previous studies have demonstrated that exercise increases whole body and skeletal muscle insulin sensitivity that is linked with increased GLUT4 at the plasma membrane following insulin stimulation and associated with muscle glycogen depletion. To assess the potential direct association between muscle glycogen and GLUT4, seven untrained, male subjects exercised for 60 min at ~75% VO peak, with muscle samples obtained by percutaneous needle biopsy immediately before and after exercise. Exercise reduced muscle glycogen content by ~43%. Read More

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November 2018
2 Reads

The role of submaximal exercise-induced skeletal muscle remodelling in heart failure with reduced ejection fraction patients.

J Physiol 2018 Nov 28. Epub 2018 Nov 28.

School of Medicine, University College Cork, Cork, Ireland.

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November 2018
3 Reads

Monitoring Exercise-Induced Muscle Fatigue and Adaptations: Making Sense of Popular or Emerging Indices and Biomarkers.

Sports (Basel) 2018 Nov 26;6(4). Epub 2018 Nov 26.

Muscle Physiology and Mechanics Group, School of Physical Education and Sports Science, University of Thessaly, Trikala 42100, Greece.

Regular exercise with the appropriate intensity and duration may improve an athlete's physical capacities by targeting different performance determinants across the endurance⁻strength spectrum aiming to delay fatigue. The mechanisms of muscle fatigue depend on exercise intensity and duration and may range from substrate depletion to acidosis and product inhibition of adenosinetriphosphatase (ATPase) and glycolysis. Fatigue mechanisms have been studied in isolated muscles; single muscle fibers (intact or skinned) or at the level of filamentous or isolated motor proteins; with each approach contributing to our understanding of the fatigue phenomenon. Read More

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November 2018

Prolonged depression of knee-extensor torque complexity following eccentric exercise.

Exp Physiol 2018 Nov 28. Epub 2018 Nov 28.

Endurance Research Group, School of Sport and Exercise Sciences, University of Kent, UK.

New Findings: What is the central question of this study? Does eccentric exercise leading to prolonged knee-extensor torque depression also result in a prolonged loss of knee-extensor torque complexity? What is the main finding and its importance? The recovery of the loss of torque complexity after eccentric exercise took 24 h, whereas after acute muscle fatigue it took 10 min. The depression of torque complexity after eccentric exercise was prolonged.

Abstract: Neuromuscular fatigue reduces the temporal structure, or complexity, of muscle torque output. Read More

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November 2018
1 Read

Unexpected postpneumonectomy exertion-induced acute right heart failure.

Tumori 2018 Nov 28:300891618812682. Epub 2018 Nov 28.

4 Department of Anesthesia, Intensive Care and Palliative Care, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Introduction:: Thoracic surgery can have serious side effects. Accurate preoperative evaluation to assess which patients with anatomically resectable disease are suitable candidates for surgery is mandatory.

Case Description:: A 58-year-old man, scheduled for left pneumonectomy for lung cancer, passed all the preoperative examinations suggested by guidelines and underwent the surgery. Read More

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November 2018
3 Reads

Effects of Exercise-Induced Fatigue on Lower Extremity Joint Mechanics, Stiffness, and Energy Absorption during Landings.

J Sports Sci Med 2018 Dec 20;17(4):640-649. Epub 2018 Nov 20.

School of Kinesiology, Shanghai University of Sport, Shanghai 200438, China.

The aim of this study was to determine the effects of two fatigue protocols on lower-limb joint mechanics, stiffness and energy absorption during drop landings. Fifteen male athletes completed landing tasks before and after two fatigue protocols (constant speed running [R-FP] and repeated shuttle sprint plus vertical jump [SJ-FP]). Sagittal plane lower-limb kinematics and ground reaction forces were recorded. Read More

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December 2018

Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats.

Brain Struct Funct 2018 Nov 26. Epub 2018 Nov 26.

Division of Brain Science, Department of Physiology, Kurume University School of Medicine, Kurume, Japan.

14-3-3γ is an important early ischemia-inducible protective factor against ischemic cell death in cerebral cortical neurons. We investigated the anti-apoptosis mechanism of enhanced 14-3-3γ mediated by preconditioning exercise-induced brain ischemic tolerance after stroke. Rats were assigned to four groups: exercise and ischemia (Ex group), ischemia and no exercise (No-Ex group), exercise and no ischemia (Ex-only group), and no exercise and ischemia (control group). Read More

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November 2018
2 Reads

Long-term, health-enhancing physical activity is associated with reduction of pain but not pain sensitivity or improved exercise-induced hypoalgesia in persons with rheumatoid arthritis.

Arthritis Res Ther 2018 Nov 26;20(1):262. Epub 2018 Nov 26.

Department of Clinical Neuroscience, Karolinska Institutet, Nobels väg 9, SE-171 77, Stockholm, Sweden.

Background: We aimed to evaluate the 1-year and 2-year outcome of a health-enhancing physical activity (HEPA) support program on global pain, pressure pain sensitivity, and exercise-induced segmental and plurisegmental hypoalgesia (EIH) in persons with rheumatoid arthritis (RA).

Methods: Thirty participants (27 women and 3 men) were recruited from a larger intervention cohort that engaged in strength training and moderate-intensity aerobic activity. Assessments were performed before the HEPA intervention and at 1-year and 2-year follow-ups. Read More

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November 2018
3 Reads

Relationship of Circulating Irisin with Body Composition, Physical Activity, and Cardiovascular and Metabolic Disorders in the Pediatric Population.

Int J Mol Sci 2018 Nov 23;19(12). Epub 2018 Nov 23.

Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Ave. Morones Prieto 3000, Monterrey N.L. 64710, Mexico.

Exercise-induced irisin, a recently discovered myokine, has been linked to insulin resistance, obesity, and other diseases in adults; however, information in children is scarce and contradictory. We analyzed the limited evidence of irisin's effects in children and adolescents, and its association with body composition, exercise training, cardiovascular risk factors, and metabolic diseases, as well as the results of dietetic interventions. Both positive and negative correlations between irisin concentrations and body mass index, fat mass, fat-free mass, and other anthropometric parameters were found. Read More

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November 2018
9 Reads

Gradient variability in hypertrophic cardiomyopathy: New insights from computer-assisted, high fidelity, rest and exercise hemodynamic analysis.

Catheter Cardiovasc Interv 2018 Nov 25. Epub 2018 Nov 25.

Cardiology Service, Brooke Army Medical Center, Fort Sam Houston, Texas.

Objectives: This study examines the intrapatient variability in peak instantaneous left ventricular outflow tract (LVOT) gradients and aortic pulse pressures during rest, exercise, and after ventricular ectopy.

Background: Although the variability in LVOT gradients in patients with hypertrophic cardiomyopathy (HCM) is well known, the predictors of such variation are not. We hypothesized that quantitative invasive analysis of gradient variation could identify useful predictors of maximal gradients. Read More

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November 2018
5 Reads

Exercise inhibits tumor growth and central carbon metabolism in patient-derived xenograft models of colorectal cancer.

Cancer Metab 2018 15;6:14. Epub 2018 Nov 15.

1Division of Medical Oncology, Duke University Medical Center, 3008 Snyderman Building, 905 S. LaSalle St, Durham, NC 27710 USA.

Background: While self-reported exercise is associated with a reduction in the risk of recurrence in colorectal cancer, the molecular mechanisms underpinning this relationship are unknown. Furthermore, the effect of exercise on intratumoral metabolic processes has not been investigated in detail in human cancers. In our current study, we generated six colorectal patient patient-derived xenografts (CRC PDXs) models and treated each PDX to voluntary wheel running (exercise) for 6-8 weeks or no exposure to the wheel (control). Read More

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November 2018
4 Reads

Allergic acute coronary syndrome in exercise-induced anaphylaxis.

Neth J Med 2018 Nov;76(9):411-414

Departments of Acute Care, Erasmus Medical Center, Rotterdam, the Netherlands.

In this case report we present a 49-year-old male who was seen in the emergency department after collapsing due to anaphylactic shock, with ECG findings suggesting myocardial ischaemia. We linked both diagnoses to Kounis syndrome, which describes an acute coronary syndrome due to an allergic event. His circulatory collapse was explained by exercise-induced anaphylaxis. Read More

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November 2018
4 Reads

Exercise capacity in COPD patients with exercise-induced pulmonary hypertension.

Int J Chron Obstruct Pulmon Dis 2018 31;13:3599-3610. Epub 2018 Oct 31.

Clinic of Allergology and Respiratory Medicine, Oslo, Norway.

Background: Pulmonary hypertension (PH) in patients with COPD is associated with reduced exercise capacity. A subgroup of COPD patients has normal mean pulmonary artery pressure (mPAP) at rest, but develops high mPAP relative to cardiac output (CO) during exercise, a condition we refer to as exercise-induced pulmonary hypertension (EIPH). We hypothesized that COPD patients with EIPH could be identified by cardiopulmonary exercise test (CPET) and that these patients have lower exercise capacity and more abnormal CPET parameters compared to COPD patients with normal hemodynamic exercise response. Read More

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October 2018
5 Reads

Towards reducing the immunogenic potential of wheat flour: omega gliadins encoded by the D genome of hexaploid wheat may also harbor epitopes for the serious food allergy WDEIA.

BMC Plant Biol 2018 Nov 21;18(1):291. Epub 2018 Nov 21.

National Institute of Agricultural Sciences, RDA, Jeonju, 54874, South Korea.

Background: Omega-5 gliadins are a group of highly repetitive gluten proteins in wheat flour encoded on the 1B chromosome of hexaploid wheat. These proteins are the major sensitizing allergens in a severe form of food allergy called wheat-dependent exercise-induced anaphylaxis (WDEIA). The elimination of omega-5 gliadins from wheat flour through biotechnology or breeding approaches could reduce the immunogenic potential and adverse health effects of the flour. Read More

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November 2018
3 Reads

Acute effect of taping on plantar pressure characteristics in athletes with exercise-induced leg pain: a description and comparison of groups.

Phys Sportsmed 2018 Nov 21:1-8. Epub 2018 Nov 21.

b Department of Marine Sports , Pukyoung National University , Busan , Republic of Korea.

Objectives: Foot pronation is considered as a potential risk factor of lower leg overuse injury. This study aimed to identify plantar pressure characteristics of elite athletes with exercise-induced leg pain in throwing athletic disciplines, and to verify the acute effect of taping for restricting foot pronation by analyzing the plantar pressure characteristics.

Methods: This study was designed as a description and comparison of throwing athletic athletes. Read More

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November 2018
3 Reads

Exercise effects on mood, and its associations with self-regulatory skills, self-efficacy, and eating changes during the year following weight-loss treatment.

Authors:
James J Annesi

Women Health 2018 Nov 21:1-15. Epub 2018 Nov 21.

a YMCA of Metro Atlanta , Atlanta , Georgia , USA.

Maintaining weight loss beyond an initial year of behavioral treatment is of concern, and understanding interrelationships of theory-based psychosocial correlates is minimal. Although exercise is universally suggested, its indirect impacts on long-term nutritional changes are unclear. Data from women with obesity (N= 129), who participated in the treatment groups of two initial trials of a new social cognitive theory-based weight-loss protocol during 2016-2017, were incorporated. Read More

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November 2018
5 Reads

Cold water immersion or LED therapy after training sessions: effects on exercise-induced muscle damage and performance in rats.

Lasers Med Sci 2018 Nov 19. Epub 2018 Nov 19.

Center of Biological Sciences, Universidade Estadual de Londrina, Londrina, Brazil.

Cryotherapy and phototherapy have been suggested as recovery methods due to their anti-inflammatory effects. They may also induce mitochondrial biogenesis, thus favoring endurance training adaptation. The aim of this study was to evaluate the anti-inflammatory and ergogenic effects of phototherapy or cold water immersion (CWI) applied daily after exercise in rats. Read More

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November 2018

Aetiology of anaphylaxis in patients referred to an immunology clinic in Colombo, Sri Lanka.

Allergy Asthma Clin Immunol 2018 8;14:81. Epub 2018 Nov 8.

3Department of Microbiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Colombo, Sri Lanka.

Background: The aetiology of anaphylaxis differs according to types of foods consumed, fauna and foliage and cultural practices. Although the aetiology of anaphylaxis in Western countries are well known, the causes in South Asian countries have not been reported. We sought to determine the causes of anaphylaxis in patients referred to an immunology clinic in Colombo, Sri Lanka. Read More

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November 2018
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Regular Practice of Moderate Physical Activity by Older Adults Ameliorates Their Anti-Inflammatory Status.

Nutrients 2018 Nov 16;10(11). Epub 2018 Nov 16.

Grup de Nutrició Comunitària i Estrès Oxidatiu, Departament de Biologia Fonamental i Ciències de la Salut, Universitat de les Illes Balears, 07122 Palma, Spain.

A chronic inflammatory state is a major characteristic of the aging process, and physical activity is proposed as a key component for healthy aging. Our aim was to evaluate the body composition, hypertension, lipid profile, and inflammatory status of older adults, and these factors' association with physical activity. A total of 116 elderly volunteers were categorized into terciles of quantitative metabolic equivalents of task (MET). Read More

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November 2018
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