4,066 results match your criteria Exercise-Induced Asthma


Generalized allergic reaction in response to exercise due to strawberry gibberellin-regulated protein: a case report.

Allergy Asthma Clin Immunol 2022 Jun 11;18(1):49. Epub 2022 Jun 11.

Department of Food Science, Kyoto Women's University, 35 Kitahiyoshi-cho, Imakumano, Higashiyama-ku, Kyoto, 605-8501, Japan.

Background: The Rosaceae family includes fruits, such as peach, apple, Japanese apricot, cherry (Prunoideae subfamily), and strawberry (Rosoideae subfamily). The allergens responsible for Rosaceae fruit allergies have been reported to include Bet v 1 and profilin, which mainly cause oral symptoms, and lipid transfer protein (LTP). Recently, gibberellin-regulated protein (GRP) has been identified as an allergen that induces generalized symptoms in peach-, orange-, and plum-related allergies. Read More

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Constant-load exercise versus high-intensity interval training on aerobic fitness in moderate to severe asthma: A RCT.

J Allergy Clin Immunol Pract 2022 May 30. Epub 2022 May 30.

Department of Physical Therapy, School of Medicine, University of São Paulo, São Paulo, Brazil.

Background: The effects of high-intensity interval training (HIIT) on dyspnea and aerobic fitness in adults with asthma are poorly understood.

Objective: To compare constant-load exercise (CLE) versus HIIT for improvements in dyspnea symptoms and clinical control in adults with moderate to severe asthma.

Methods: Participants were randomized into 2 groups: CLE (n=27; started with 70% of maximal watts (Wmax) obtained during cardiopulmonary exercise testing (CPET)) and HIIT (n=28; started with 80% and increased until 140% Wmax). Read More

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International Olympic Committee (IOC) consensus statement on acute respiratory illness in athletes part 2: non-infective acute respiratory illness.

Br J Sports Med 2022 May 27. Epub 2022 May 27.

Medical and Scientific Department, International Olympic Committee, Lausanne, Switzerland.

Acute respiratory illness (ARill) is common and threatens the health of athletes. ARill in athletes forms a significant component of the work of Sport and Exercise Medicine (SEM) clinicians. The aim of this consensus is to provide the SEM clinician with an overview and practical clinical approach to non-infective ARill in athletes. Read More

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Cut-off value for exercise-induced bronchoconstriction based on the features of the airway obstruction.

PLoS One 2022 26;17(5):e0268969. Epub 2022 May 26.

Division of Allergy, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

The current cut-off value for diagnosing exercise-induced bronchoconstriction (EIB) in adults-percent fall in FEV1 (ΔFEV1) ≥ 10% after exercise challenge test (ECT)-has low specificity and weak evidences. Therefore, this study aimed to identify the cut-off value for EIB that provides the highest diagnostic sensitivity and specificity. Participants who underwent the ECT between 2007 and 2018 were categorized according to ΔFEV1: definite EIB (ΔFEV1 ≥ 15%), borderline (10% ≤ ΔFEV1 < 15%), and normal (ΔFEV1 < 10%). Read More

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Results From a National Survey of Asthma Provider Beliefs and Practices Regarding Exercise and Asthma: A Work Group Report of the AAAAI Committee on Sports, Exercise, and Fitness.

J Allergy Clin Immunol Pract 2022 May 20. Epub 2022 May 20.

Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois at Chicago, Chicago, Ill.

Background: National Heart, Lung, and Blood Institute guidelines recommend regular physical activity (PA) for patients with asthma. Health care provider (HCP) counseling represents an effective approach to optimizing patient PA. However, current exercise rates among asthma patients are suboptimal, which suggests that counseling may be improved. Read More

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Anaphylaxis in Chinese Children with Pollen Sensitization: Triggers, Clinical Presentation, and Acute Management.

J Asthma Allergy 2022 16;15:633-643. Epub 2022 May 16.

Department of Allergy, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health; Key Laboratory of Major Diseases in Children, Ministry of Education; National Clinical Research Center for Respiratory Diseases, Beijing, People's Republic of China.

Purpose: Pollen sensitization is increasing in children. However, there is little evidence regarding the characteristics of anaphylaxis in individuals with pollen sensitization.

Patients And Methods: We conducted a retrospective study of patients with anaphylaxis combined with pollen sensitization who attended an allergy department in a tertiary children's hospital from 2014 to 2021. Read More

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Experiences of exercise in patients with asthma: qualitative analysis of discussions in a UK asthma online community.

BJGP Open 2022 Apr 29. Epub 2022 Apr 29.

Asthma UK Centre for Applied Research, (AUKCAR) Wolfson Institute of Population Health, Queen Mary University of London, London, UK

Background: Engagement with exercise in adults with asthma is suboptimal. Limited information is available regarding factors affecting engagement with exercise.

Aim: To explore experiences of exercise and linked unmet needs in adults with asthma. Read More

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Risk factors for severe reactions in food allergy: Rapid evidence review with meta-analysis.

Allergy 2022 Apr 20. Epub 2022 Apr 20.

NIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust, Faculty of Medicine, University of Southampton, Southampton, UK.

This rapid review summarizes the most up to date evidence about the risk factors for severe food-induced allergic reactions. We searched three bibliographic databases for studies published between January 2010 and August 2021. We included 88 studies and synthesized the evidence narratively, undertaking meta-analysis where appropriate. Read More

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Association of rhinitis with asthma prevalence and severity.

Sci Rep 2022 04 16;12(1):6389. Epub 2022 Apr 16.

Traslational Research In Airway Diseases Group (TRIAD), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.

Asthma and rhinitis often co-exist in the same patient. Although some authors observed a higher prevalence and/or greater severity of asthma in patients with rhinitis, this view is not homogeneous and the debate continues. The aim of our study is to describe the prevalence of rhinitis in children and adolescents and to analyse their relationship with the prevalence of asthma. Read More

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Cleaning Products Commonly Used in Oklahoma Family Child Care Homes: Implications for Respiratory Risk and Children's Health.

Int J Environ Res Public Health 2022 04 3;19(7). Epub 2022 Apr 3.

Department of Health Promotion Sciences, Hudson College of Public Health, University of Oklahoma Health Sciences Center, 801 N.E. 13th Street, Oklahoma City, OK 73104, USA.

Little is known about the cleaning products used by early care and education programs that contribute to childhood asthma, particularly in Oklahoma where rates of uncontrolled asthma are higher than national rates (60.0% vs. 50. Read More

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A breathing mask attenuates acute airway responses to exercise in sub-zero environment in healthy subjects.

Eur J Appl Physiol 2022 Jun 7;122(6):1473-1484. Epub 2022 Apr 7.

Swedish Winter Sports Research Centre, Department of Health Sciences, Mid Sweden University, Östersund, Sweden.

Purpose: Cold air exposure is associated with increased respiratory morbidity and mortality. Repeated inhalation of cold and dry air is considered the cause of the high prevalence of asthma among winter endurance athletes. This study assessed whether a heat- and moisture-exchanging breathing device (HME) attenuates airway responses to high-intensity exercise in sub-zero temperatures among healthy subjects. Read More

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The impact of identifying laryngeal obstruction syndromes on reducing treatment of pediatric asthma: A systematic review.

Pediatr Pulmonol 2022 06 22;57(6):1401-1415. Epub 2022 Apr 22.

Department of Pediatrics, University of Alberta, Edmonton, Canada.

Inducible laryngeal obstruction (ILO) in children is underrecognized. This systematic review characterizes the scientific evidence on the impact of pediatric ILO diagnosis and treatment on asthma medication use. This review, registered with PROSPERO (CRD42020209168), utilized database searches in MEDLINE, EMBASE, CINAHL, and Web of Science from inception to October 2020. Read More

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COVID-19 symptoms are reduced by targeted hydration of the nose, larynx and trachea.

Sci Rep 2022 03 29;12(1):4599. Epub 2022 Mar 29.

Sensory Cloud, 650 East Kendall St, Cambridge, MA, USA.

Dehydration of the upper airways increases risks of respiratory diseases from COVID-19 to asthma and COPD. We find in human volunteer studies involving 464 human subjects in Germany, the US, and India that respiratory droplet generation increases by up to 4 orders of magnitude in dehydration-associated states of advanced age (n = 357), elevated BMI-age (n = 148), strenuous exercise (n = 20) and SARS-CoV-2 infection (n = 87), and falls with hydration of the nose, larynx and trachea by calcium-rich hypertonic salts. We also find in a protocol of exercise-induced airway dehydration that hydration of the airways by calcium-rich salts increases oxygenation relative to a non-treatment control (P < 0. Read More

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Overuse of Short-Acting Beta-2 Agonists (SABAs) in Elite Athletes: Hypotheses to Explain It.

Sports (Basel) 2022 Mar 2;10(3). Epub 2022 Mar 2.

MINT, University Angers, Inserm, CNRS, SFR ICAT, F-49000 Angers, France.

The use of short-acting beta-2 agonists (SABAs) is more common in elite athletes than in the general population, especially in endurance sports. The World Anti-Doping Code places some restrictions on prescribing inhaled β2-agonists. These drugs are used in respiratory diseases (such as asthma) that might reduce athletes' performances. Read More

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An Algorithm for Strategic Continuation or Restriction of Asthma Medication Prior to Exercise Challenge Testing in Childhood Exercise Induced Bronchoconstriction.

Front Pediatr 2022 22;10:800193. Epub 2022 Feb 22.

Department of Paediatrics, Medisch Spectrum Twente, Enschede, Netherlands.

Exercise induced bronchial (EIB) constriction is a common and highly specific feature of pediatric asthma and should be diagnosed with an exercise challenge test (ECT). The impact of EIB in asthmatic children's daily lives is immense, considering the effects on both physical and psychosocial development. Monitoring childhood asthma by ECT's can provide insight into daily life disease burden and the control of asthma. Read More

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February 2022

Is airway damage during physical exercise related to airway dehydration? Inputs from a computational model.

J Appl Physiol (1985) 2022 04 24;132(4):1031-1040. Epub 2022 Feb 24.

Laboratoire J. A. Dieudonné, UMR CNRS 7351, Université Côte d'Azur, Nice, France.

In healthy subjects, at low minute ventilation (V̇e) during physical exercise, the water content and temperature of the airways are well regulated. However, with the increase in V̇e, the bronchial mucosa becomes dehydrated and epithelial damage occurs. Our goal was to demonstrate the correspondence between the ventilatory threshold inducing epithelial damage, measured experimentally, and the dehydration threshold, estimated numerically. Read More

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Ventilation Rates Achieved in Eucapnic Voluntary Hyperpnea Challenge and Exercise-Induced Bronchoconstriction Diagnosis in Young Patients with Asthma.

Lung 2022 04 23;200(2):229-236. Epub 2022 Feb 23.

Center for Research in Allergy and Clinical Immunology, Hospital das Clínicas, Universidade Federal de Pernambuco, Rua Luiz Guimarães, 411, apto 301-a, CEP-52061-160, Poço da Panela, Recife, Brazil.

Purpose: Exercise-induced bronchoconstriction (EIB) affects approximately 50% of young asthma patients, impairing their participation in sports and physical activities. Eucapnic voluntary hyperpnea (EVH) is an approved surrogate challenge to exercise for objective EIB diagnosis, but the required minimum target hyperventilation rates remain unexplored in this population. This study aimed to evaluate the association between the achieved ventilation rates (VRs) during a challenge and EIB-compatible response (EIB-cr) in young asthma patients. Read More

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Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'.

Br J Sports Med 2022 Jun 22;56(11):622-629. Epub 2022 Feb 22.

Department of Pediatric and Adolescent Medicine, Haukeland Universityhospital, Bergen, Norway.

Exercise-induced laryngeal obstruction (EILO) is caused by paradoxical inspiratory adduction of laryngeal structures during exercise. EILO is an important cause of upper airway dysfunction in young individuals and athletes, can impair exercise performance and mimic lower airway dysfunction, such as asthma and/or exercise-induced bronchoconstriction. Over the past two decades, there has been considerable progress in the recognition and assessment of EILO in sports medicine. Read More

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Exercise-Induced Bronchospasm in Elite Athletes.

Cureus 2022 Jan 3;14(1):e20898. Epub 2022 Jan 3.

Pulmonology, University of Thessaly, Larissa, GRC.

Exercise is one of the most common triggers of exercise-induced bronchospasm (EIB), with less trained athletes showing more symptoms. Exercise-induced bronchospasm is a common and frequent problem among elite athletes with obvious implications on competing performance, health, and quality of life. Classical pathways in the development of EIB in this population include the osmotic and the thermal theory as well as the presence of epithelial injury and inflammation in the airway. Read More

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January 2022

Impact of Inhaled Corticosteroids on the Modulation of Respiratory Defensive Reflexes During Artificial Limb Exercise in Ovalbumin-Sensitized Rabbits.

Front Physiol 2021 25;12:804577. Epub 2022 Jan 25.

EA 3450 DevAH-Development, Adaptation and Disadvantage, Cardiorespiratory Regulations and Motor Control, Université de Lorraine, Nancy, France.

Introduction: Cough is a major lower airway defense mechanism that can be triggered by exercise in asthma patients. Studies on cough reflex in experimental animal models revealed a decrease of cough reflex sensitivity during exercise in healthy animals, but a lack of desensitization in ovalbumin-sensitized rabbits. The aim of our study is to evaluate the impact of inhaled corticosteroids on cough reflex during artificial limb exercise in an animal model of eosinophilic airway inflammation. Read More

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January 2022

The continuous laryngoscopy exercise test in severe or in difficult-to-treat asthma in adults: a systematic review.

J Asthma 2022 Feb 6:1-10. Epub 2022 Feb 6.

Pulmonary Department, Heart and Lung Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.

Objective: A systematic review was performed to determine if the continuous laryngoscopy exercise test (CLE) has been used in the diagnostics of exercise dyspnea in adults with asthma, and whether inducible laryngeal obstruction (ILO) is found in those with asthma or with severe or difficult-to-treat asthma.

Data Sources: We used Scopus and PubMed databases. The articles published up to 13 August 2019 were considered. Read More

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February 2022

Evaluating Children and Adolescents with Suspected Exercise Induced Asthma: Real Life Data.

Klin Padiatr 2022 Feb 3. Epub 2022 Feb 3.

Division of Allergy, Pulmonology and Cystic fibrosis, Department for Children and Adolescents, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany.

Objective: Exercise-induced bronchoconstriction (EIB) occurs frequently in children and adolescents and may be a sign of insufficient asthma control. EIB is often evaluated by respiratory symptoms, spirometry, eNO measurement and methacholine testing (MCT) instead of time consuming exercise test. Aim of this study was to analyse the amount of patients for which an exercise challenge in a cold chamber (ECC) was needed for a clear EIB diagnosis, to characterize EIB phenotypes and the incidence of exercise induced laryngeal obstruction (EILO) in a large cohort of patients with EIB. Read More

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February 2022

Conundrums in the breathless athlete; exercise-induced laryngeal obstruction or asthma?

Scand J Med Sci Sports 2022 Jun 8;32(6):1041-1049. Epub 2022 Feb 8.

Department of Pediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.

Purpose: Exercise-induced bronchoconstriction (EIB) and exercise-induced laryngeal obstruction (EILO) are the two disorders commonly considered when athletes complain of exertional dyspnea. They are highly different but often confused. We aimed to address this diagnostic challenge and its consequences in elite athletes. Read More

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Exercise Limitation in Children and Adolescents with Mild-to-Moderate Asthma.

J Asthma Allergy 2022 18;15:89-98. Epub 2022 Jan 18.

Pediatric Respiratory Unit, University of Patras Medical School, Patras, Greece.

Background: Children with uncontrolled asthma are less tolerant to exercise due to ventilatory limitation, exercise-induced bronchoconstriction (EIB), or physical deconditioning. The contribution of these factors in children with controlled mild-to-moderate asthma is unknown.

Objective: To explore the underlying mechanisms of reduced exercise capacity in children with controlled mild-to-moderate asthma. Read More

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January 2022

Classroom-Based Strategies to Reduce Disparities in Physical Activity Among Children with Asthma.

Prev Sci 2022 05 26;23(4):587-597. Epub 2022 Jan 26.

School of Kinesiology, University of Michigan, Ann Arbor, MI, USA.

Children with asthma often experience physical activity (PA) induced symptoms 5-15 min following the start of exercise. Classroom PA breaks provide short intermittent bouts of PA and may represent a novel strategy to safely promote PA participation in this clinical population. The purpose of this study was to determine the feasibility of a classroom-based PA intervention, Interrupting Prolonged Sitting with Activity (InPACT), where teachers implement 5 × 4-min moderate-to-vigorous physical activity (MVPA) breaks throughout the school day. Read More

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The Need for Testing-The Exercise Challenge Test to Disentangle Causes of Childhood Exertional Dyspnea.

Front Pediatr 2021 6;9:773794. Epub 2022 Jan 6.

Ludwig Engel Centre for Respiratory Research, Westmead Institute for Medical Research, Westmead, NSW, Australia.

Exertional dyspnea is a common symptom in childhood which can induce avoidance of physical activity, aggravating the original symptom. Common causes of exertional dyspnea are exercise induced bronchoconstriction (EIB), dysfunctional breathing, physical deconditioning and the sensation of dyspnea when reaching the physiological limit. These causes frequently coexist, trigger one another and have overlapping symptoms, which can impede diagnoses and treatment. Read More

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January 2022

Exercise-Induced Bronchoconstriction in Children.

Front Med (Lausanne) 2021 3;8:814976. Epub 2022 Jan 3.

Department of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", Naples, Italy.

Exercise-induced bronchoconstriction (EIB) is a transient airflow obstruction, typically 5-15 min after physical activity. The pathophysiology of EIB is related to the thermal and osmotic changes of the bronchial mucosa, which cause the release of mediators and the development of bronchoconstriction in the airways. EIB in children often causes an important limitation to physical activities and sports. Read More

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January 2022

Exercise Related Respiratory Problems in the Young-Is It Exercise-Induced Bronchoconstriction or Laryngeal Obstruction?

Front Pediatr 2021 3;9:800073. Epub 2022 Jan 3.

Department of Paediatrics and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.

Complaints of breathlessness during heavy exercise is common in children and adolescents, and represent expressions of a subjective feeling that may be difficult to verify and to link with specific diagnoses through objective tests. Exercise-induced asthma and exercise-induced laryngeal obstruction are two common medical causes of breathing difficulities in children and adolescents that can be challenging to distinguish between, based only on the complaints presented by patients. However, by applying a systematic clinical approach that includes rational use of tests, both conditions can usually be diagnosed reliably. Read More

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January 2022

Inappropriate sinus tachycardia-induced cardiomyopathy with severe functional mitral regurgitation and successful treatment with ivabradine.

J Cardiol Cases 2022 Jan 20;25(1):6-9. Epub 2021 Jun 20.

Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center, Kumamoto-city, Japan.

Ivabradine increases stroke volume, but does not have a negative impact on blood pressure (BP). Thus, a patient with low BP can benefit from treatment with ivabradine. A 72-year-old Japanese woman with asthma and chronic bronchitis presented with dyspnea. Read More

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January 2022