158,012 results match your criteria Evidence-based dentistry[Journal]


The neurophysiological and neurochemical effects of alcohol on the brain are inconsistent with current evidence based models of sleepwalking.

Authors:
Mark R Pressman

Sleep Med Rev 2018 Nov 10;43:92-95. Epub 2018 Nov 10.

Sleep Medicine Services, Lankenau Medical Center, Wynnewood, PA, USA; Lankenau Institute for Medical Research, Wynnewood, PA, USA; Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA; Charles Widger School of Law, Villanova University, Villanova, PA, USA. Electronic address:

The DSM-5 and ICSD-3 have removed alcohol from the list of potential triggers for sleepwalking due to the lack of empirical evidence. Recent imaging and EEG based studies of sleepwalking and confusional arousals have provided a more data-based method of examining if alcohol is compatible with what is known about the neurophysiology and neurochemistry of sleepwalking. These studies have demonstrated a deactivation of the frontal areas of the brain, while the cingulate or motor cortex remains active and characterized activation in the form of beta EEG. Read More

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November 2018
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Measuring Value in Post-Acute Care.

Arch Phys Med Rehabil 2018 Dec 8. Epub 2018 Dec 8.

John F. Butzer Center for Research and Innovation, Mary Free Bed Rehabilitation Hospital, Grand Rapids, MI; Division of Rehabilitation, Michigan State University College of Human Medicine, Grand Rapids, MI.

The value of post-acute care is unclear. While experienced clinicians understand the appropriateness of each specific site of post-acute care, clear evidence-based guidelines are not available, and many referrals to post-acute care today are made based on bed availability rather than patient need. Measuring value (value = outcomes / cost) for the entire episode of care has been proposed as an effective method to both evaluate and enable faster innovation in care. Read More

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December 2018

Comparison of Quality Oncology Practice Initiative Metrics in Solid Tumor Oncology Clinic With or Without Concomitant Supportive Oncology Consultation.

J Oncol Pract 2018 Dec;14(12):e786-e793

Icahn School of Medicine at Mount Sinai, New York, NY; and The Everett Clinic, Providence Regional Medical Center, Everett, WA.

Purpose:: The Quality Oncology Practice Initiative (QOPI) is a quality measurement and improvement program designed to assess practice performance for various consensus-based and evidence-based measures. In this study, we evaluated differences in QOPI metrics met among patients with advanced solid cancer receiving routine oncologic care alone (routine care) compared with patients receiving integrated oncology and specialty-level palliative care (supportive care).

Methods:: We conducted a retrospective chart review of 100 randomly selected patients treated between June 2013 and June 2015 from our supportive care group and matched these patients to 100 routine care group patients on the basis of tumor type and initial oncology visit date. Read More

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December 2018

Coming ready or not! An integrative review examining new graduate nurses' transition in acute care.

Int J Nurs Pract 2018 Dec 9:e12714. Epub 2018 Dec 9.

Department of Rural Health, University of Newcastle, Taree, Australia.

Aims: To synthesize the scientific evidence about new graduate nurses' transition to practice in the acute care setting and consider implications for nurses and nursing practice.

Background: Despite the vast amount of literature on new graduate nurses' transition to practice, the transition of new graduate nurses is a global issue and remains at the forefront of discussions within the nursing community.

Design: An integrative review. Read More

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December 2018

Erythrocyte sedimentation rate as an independent prognostic marker for mortality: a prospective population-based cohort study.

J Intern Med 2018 Dec 9. Epub 2018 Dec 9.

Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

Background: A very high erythrocyte sedimentation rate (ESR) is usually an indication of underlying pathology. Additionally, a moderately elevated ESR may also be attributable to biological ageing. Whether the ESR is a prognostic factor for mortality, regardless of age, has been scarcely investigated. Read More

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December 2018

Acute cellular rejection treatment outcomes stratified by Banff grade in pediatric kidney transplant.

Pediatr Transplant 2018 Dec 7:e13334. Epub 2018 Dec 7.

Pediatric Nephrology at Children's Healthcare of Atlanta, Atlanta, Georgia.

Introduction: There are limited data to guide optimal treatment strategies for acute cellular rejection (ACR) based on Banff grade for pediatric kidney transplant recipients. This report reviews a large pediatric transplant center's experience with ACR.

Materials And Methods: A retrospective analysis of pediatric kidney transplant recipients at our center from 2007 to 2014 was performed. Read More

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December 2018

Science for Policy: A Case Study of Scientific Polarization, Values, and the Framing of Risk and Uncertainty.

Risk Anal 2018 Dec 10. Epub 2018 Dec 10.

The Institute for Resources, Environment and Sustainability (IRES), University of British Columbia, Vancouver, British Columbia, Canada.

It is well documented that more research can lead to hardened positions, particularly when dealing with complex, controversial, and value-laden issues. This study is an attempt to unveil underlying values in a contemporary debate, where both sides use scientific evidence to support their argument. We analyze the problem framing, vocabulary, interpretation of evidence, and policy recommendations, with particular attention to the framing of nature and technology. Read More

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December 2018

How often are bath emollients prescribed to children with atopic eczema in primary care in England? A cross-sectional study.

Br J Dermatol 2018 Dec 10. Epub 2018 Dec 10.

Centre of Evidence Based Dermatology, University of Nottingham, King's Meadow Campus, Lenton Lane, Nottingham, NG7 2NR.

Atopic eczema is one of the most burdensome skin diseases across the globe and affects up to 20% of children in the UK. The mainstay of treatment is regular use of emollients including leave-on emollients, soap substitutes and emollient bath additives. However, the lack of evidence to support the use of bath additives has led some to question their role in atopic eczema management. Read More

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December 2018
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Pharmacotherapy in Older Adults with Cardiovascular Disease: Report from an American College of Cardiology, American Geriatrics Society, and National Institute on Aging Workshop.

J Am Geriatr Soc 2018 Dec 7. Epub 2018 Dec 7.

Cardiovascular Division, Department of Internal Medicine, Washington University, St. Louis, Missouri.

Objectives: To identify the top priority areas for research to optimize pharmacotherapy in older adults with cardiovascular disease (CVD).

Design: Consensus meeting.

Setting: Multidisciplinary workshop supported by the National Institute on Aging, the American College of Cardiology, and the American Geriatrics Society, February 6-7, 2017. Read More

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December 2018

Now More Than Ever: The Importance of Reporting Evidence-Based Science.

Authors:
Jan A Nolta

Stem Cells 2018 Dec 11. Epub 2018 Dec 11.

University of California Davis Health System, Stem Cell Program, Sacramento, California, USA.

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December 2018

Does a bounding exercise program prevent hamstring injuries in adult male soccer players? - A cluster -RCT.

Scand J Med Sci Sports 2018 Dec 9. Epub 2018 Dec 9.

Utrecht University, University Medical Center Utrecht, Rudolf Magnus Institute of Neurosciences, Department Rehabilitation, Physical Therapy Science & Sports, Utrecht, The Netherlands.

Background: Although the Nordic Hamstring Exercise (NHE) prevents hamstring injury in soccer players effectively, the annual incidence of these injuries still increases. This may be because of poor long-term compliance with the program. Furthermore, the timing and amplitude of gluteal and core muscle activation seem to play an important role in hamstring injury prevention, the NHE program was not designed to improve activation of these muscles. Read More

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December 2018

Wait times for endoscopic sinus surgery influence patient-reported outcome measures in patients with chronic rhinosinusitis who fulfill appropriateness criteria.

Int Forum Allergy Rhinol 2018 Dec 10. Epub 2018 Dec 10.

Division of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

Background: Previous studies on the impact of wait times for endoscopic sinus surgery (ESS) in medically recalcitrant chronic rhinosinusitis (rCRS) have not examined its influence on the 5 distinct symptoms domains of the 22-item Sino-Nasal Outcome Test (SNOT-22), and have not applied evidence-based surgical indications. Our primary study objective was to investigate the impact of ESS wait times on postoperative SNOT-22 global and symptom domain scores in patients with rCRS deemed "appropriate" surgical candidates.

Methods: This was a retrospective analysis of adult patients with rCRS undergoing ESS, categorized as "appropriate" surgical candidates. Read More

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December 2018

The American Headache Society Position Statement On Integrating New Migraine Treatments Into Clinical Practice.

Authors:

Headache 2018 Dec 10. Epub 2018 Dec 10.

Objective: To provide healthcare professionals with updated guidance in the use of novel preventive and acute treatments for migraine in adults.

Background: The principles of preventive and acute pharmacotherapy for patients with migraine have been outlined previously, but the emergence of new technologies and treatments, as well as new formulations of previously established treatments, has created a need for an updated guidance on the preventive and acute treatment of migraine.

Methods: This statement is based on a review of existing guidelines and principles for preventive and acute treatment of migraine, as well as the results of recent clinical trials of drugs and devices for these indications. Read More

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December 2018

Incidence of severe critical events in paediatric anaesthesia in the United Kingdom: secondary analysis of the anaesthesia practice in children observational trial (APRICOT study).

Anaesthesia 2018 Dec 10. Epub 2018 Dec 10.

Department of Paediatric Anaesthesia and Pain Management, University of Glasgow, Glasgow, Scotland, UK.

The anaesthesia practice in children observational trial of 31,127 patients in 261 European hospitals revealed a high (5.2%) incidence of severe critical events in the peri-operative period and wide variability in practice. A sub-analysis of the UK data was undertaken to investigate differences compared with the non-UK cohort in the incidence and nature of peri-operative severe critical events and to attempt to identify areas for quality improvement. Read More

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December 2018

Rückkehr in das Erwerbsleben nach kurativer Therapie von Kopf-Hals-Karzinomen.

Laryngorhinootologie 2018 Dec 10;97(12):838-845. Epub 2018 Dec 10.

Universitätsklinikum Leipzig AöR Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde.

Objective: Reintegration of cancer patients into occupational life is an important social and economic factor. Data for the "return to work" in Head and Neck Cancer (HNC) patients are sparse, especially compared with other tumor entities.

Material And Methods: In a selective literature research, original articles dealing with the theme complex "return to work in patients with HNC", between 1997 and 2018 were included and analyzed. Read More

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December 2018

Evaluating centralized technical assistance as an implementation strategy to improve cancer prevention and control.

Cancer Causes Control 2018 Dec 7. Epub 2018 Dec 7.

Prevention Research Center, Brown School, Washington University in St. Louis, One Brookings Drive, Campus, Box 1196, St. Louis, MO, 63130, USA.

Purpose: In 2015-2016, the Comprehensive Cancer Control National Partnership provided technical assistance workshops to support 22 cancer coalitions in increasing human papillomavirus (HPV) vaccination uptake and increasing colorectal cancer (CRC) screening in their local communities. As national efforts continue to invest in providing technical assistance, there is a current gap in understanding its use as a strategy to accelerate implementation of evidence-based interventions (EBIs) for cancer prevention. The objective of this study was to evaluate the impact of technical assistance on the participants' knowledge, attitudes, and skills for implementing EBIs in their local context and enhancing state team collaboration. Read More

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December 2018

"Creative Financing": Funding Evidence-Based Interventions in Human Service Systems.

J Behav Health Serv Res 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive (8012), La Jolla, CA, 92093-0812, USA.

Implementation and sustainment of evidence-based interventions (EBIs) is influenced by outer (e.g., broader environments in which organizations operate) and inner (e. Read More

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December 2018

Perspectives on a Stage-Based Treatment for Posttraumatic Stress Disorder Among Dialectical Behavior Therapy Consumers in Public Mental Health Settings.

Community Ment Health J 2018 Dec 7. Epub 2018 Dec 7.

Department of Psychology, University of Washington, Box 351635, Seattle, WA, 98195, USA.

Difficulties with consumer engagement are a common barrier to implementing trauma-focused evidence-based psychotherapies (TF-EBPs). Potential methods of increasing engagement include utilizing a stage-based treatment approach, and involving consumers in implementation efforts. This mixed method study explored consumers' perspectives on a stage-based TF-EBP, Dialectical Behavior Therapy (DBT) with the DBT Prolonged Exposure (DBT PE) protocol. Read More

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December 2018

Unicompartmental versus total knee arthroplasty for knee osteoarthritis.

Eur J Orthop Surg Traumatol 2018 Dec 7. Epub 2018 Dec 7.

Department of Orthopaedics, RWTH Aachen University Clinic, Pauwelsstraße 30, 52074, Aachen, Germany.

Purpose: In the last couple of years, a significant amount of studies comparing the UKA and TKA for unicompartmental knee osteoarthritis have been published. However, there is a lack of recent meta-analysis comparing the two implants. Since the number of performed UKAs is currently increasing and the indications are obsolete, it becomes important to update current evidences and outcomes. Read More

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December 2018

Retrograde fixation of the lesser trochanter in the adolescent: new surgical technique and clinical results of two cases.

Arch Orthop Trauma Surg 2018 Dec 10. Epub 2018 Dec 10.

Department of Orthopaedic Sports Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Introduction: Avulsions of the lesser femoral trochanter are rare injuries in the adolescent population. An acute avulsion causes severe functional impairment with compromised hip flexion. Recent literature reports the superiority of surgical treatment for apophyseal avulsion fractures of the pelvis in adolescents. Read More

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December 2018

Supercooled Liquid Serum Physiologic Solution Instantly Crystallized on the Nurse Table Used for Cooling of Periorbital Region During Rhinoplasty.

Aesthetic Plast Surg 2018 Dec 10. Epub 2018 Dec 10.

Institut de Biologie Paris-Seine (IBPS), CNRS, UMR 8256, Inserm ERL U1164, Biological Adaptation and Ageing, Sorbonne Université, 75005, Paris, France.

Introduction: Formation of less periorbital ecchymosis in post-operative period of rhinoplasty is a popular trend. We present the use of instantly crystallizing supercooled serum physiologic solution for periorbital cooling.

Physics Of Supercooling: There are circumstances in which water temperature drops below its freezing point, but no phase transition happens while water remains in the liquid phase. Read More

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December 2018

Ultrasound-Guided Bilateral Erector Spinae Block Versus Tumescent Anesthesia for Postoperative Analgesia in Patients Undergoing Reduction Mammoplasty: A Randomized Controlled Study.

Aesthetic Plast Surg 2018 Dec 10. Epub 2018 Dec 10.

Anesthesiology and Reanimation, Kahramanmaraş Sutcu Imam University School of Medicine, Kahramanmaras, Turkey.

Purpose: The aim of this prospective, randomized, double-blind study was to compare the tumescent anesthesia method and erector spinae block with respect to postoperative analgesia consumption, pain scores and patient satisfaction, in patients receiving breast reduction surgery under general anesthesia.

Methods: The study included 44 females, aged 20-65 years, who were to undergo breast reduction surgery, without adjunctive liposuction on the breast. Using the closed envelope method, the patients were randomly separated into two groups to receive tumescent anesthesia or erector spinae block (ESB). Read More

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December 2018

Comprehensive cancer control planning in the Pacific: the Cancer Council of the Pacific Islands a multi-national regional coalition.

Cancer Causes Control 2018 Dec 10. Epub 2018 Dec 10.

Cancer Council of the Pacific Islands, Yap State Department of Health Services, Yap State, Federated States of Micronesia, c/o Department of Family Medicine and Community Health, John A. Burns School of Medicine, University of Hawai'i, 651 Ilalo Street, MEB 224, Honolulu, HI, 96813, USA.

Introduction: In the early 1990s, a comprehensive cancer control (CCC) approach was developed in the United States (US). In 2003, the US-Affiliated Pacific Islands (USAPI) adopted the CCC approach through a regional coalition, the Cancer Council of the Pacific Islands (CCPI). Using the CCC approach, the CCPI developed jurisdiction-specific cancer coalitions and initiated their respective cancer plans. Read More

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December 2018

A glossary of user-centered design strategies for implementation experts.

Transl Behav Med 2018 Dec 7. Epub 2018 Dec 7.

Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.

User-centered design (UCD), a discipline that seeks to ground the design of an innovation in information about the people who will ultimately use that innovation, has great potential to improve the translation of evidence-based practices from behavioral medicine research for implementation in health care settings. UCD is a diverse, innovative field that remains highly variable in terms of language and approaches. Ultimately, we produced a glossary of UCD-related strategies specifically for experts in implementation research and practice, with the goal of promoting interdisciplinary collaboration in implementation efforts. Read More

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December 2018

European consensus-based recommendations for the diagnosis and treatment of rare paediatric vasculitides - the SHARE initiative.

Rheumatology (Oxford) 2018 Dec 7. Epub 2018 Dec 7.

Department of Paediatric Rheumatology, Alder Hey Children's Hospital, Liverpool, UK.

Objectives: The European initiative Single Hub and Access point for paediatric Rheumatology in Europe (SHARE) aimed to optimize care for children with rheumatic diseases. Systemic vasculitides are very rare in children. Consequently, despite recent advances, paediatric-specific information is sparse. Read More

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December 2018

European consensus-based recommendations for the diagnosis and treatment of Kawasaki disease - the SHARE initiative.

Rheumatology (Oxford) 2018 Dec 7. Epub 2018 Dec 7.

Department of Paediatric Rheumatology, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.

Objectives: The European Single Hub and Access point for paediatric Rheumatology in Europe initiative aimed to optimize care for children with rheumatic diseases. Kawasaki disease (KD) is the most common cause of acquired heart disease in children and an important cause of long-term cardiac disease into adulthood. Prompt diagnosis and treatment of KD is difficult due to the heterogeneity of the disease but is crucial for improving outcome. Read More

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December 2018
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Translational approaches in treatment-resistant depression based on animal model.

Rom J Morphol Embryol 2018 ;59(3):955-964

Department of Psychiatry, "Dr. Carol Davila" Central Military Emergency University Hospital, Bucharest, Romania;

An intensively researched and yet poorly understood phenomenon, both at clinical and neurobiological level, is the determinism of treatment-resistant depression. Even more controversial are the stages of approaching therapeutically this pathology because there are no evidence-based recommendations stating that a pharmacological agent is superior to another, on medium and long-term. Due to the lack of "golden standard" approaches, physician's experience, therapeutic alliance and a close monitoring stand as the most useful good practices in the treatment of resistant depression. Read More

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January 2018
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Comparison of complementary diagnostic tests in cerebrospinal fluid and serum for neurocysticercosis.

Heliyon 2018 Dec 1;4(12):e00991. Epub 2018 Dec 1.

Instituto de Investigación en Salud Pública y Zoonosis, Facultad de Medicina Veterinaria y Zootecnia, Universidad Central del Ecuador, Quito, Ecuador.

The role of immunologic tests in the diagnosis of neurocysticercosis (NC) is controversial and few studies have made comparisons among them. The objective of this study was to compare immunological tests in both serum and cerebrospinal fluid (CSF) for the diagnosis of NC. We conducted a case-control study in Cuenca, Ecuador, enrolling patients with NC (N = 24) and matching them with other neurosurgical patients (N = 18). Read More

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December 2018

Development of a Self-Determination Theory-Based Physical Activity Intervention for Aged Care Workers: Protocol for the Activity for Well-being Program.

Front Public Health 2018 26;6:341. Epub 2018 Nov 26.

Alliance for Research in Exercise, Nutrition and Activity (ARENA), School of Health Sciences, University of South Australia, Adelaide, SA, Australia.

Despite the well-established benefits of regular participation in physical activity, many Australians still fail to maintain sufficient levels. More self-determined types of motivation and more positive affect during activity have been found to be associated with the maintenance of physical activity behaviour over time. Need-supportive approaches to physical activity behaviour change have previously been shown to improve quality of motivation and psychological well-being. Read More

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November 2018
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Global emergency care clinical practice guidelines: A landscape analysis.

Afr J Emerg Med 2018 Dec 24;8(4):158-163. Epub 2018 Oct 24.

Centre for Evidence-based Health Care, Division of Epidemiology and Biostatistics, Stellenbosch University, South Africa.

Introduction: An adaptive guideline development method, as opposed to a guideline development, is dependent on access to existing high-quality up-to-date clinical practice guidelines (CPGs). We described the characteristics and quality of CPGs relevant to prehospital care worldwide, in order to strengthen guideline development in low-resource settings for emergency care.

Methods: We conducted a descriptive study of a database of international CPGs relevant to emergency care produced by the African Federation for Emergency Medicine (AFEM) CPG project in 2016. Read More

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December 2018

The case for investing in public health surveillance in low- and middle-income countries.

Afr J Emerg Med 2018 Dec 31;8(4):127-128. Epub 2018 Jul 31.

Department of Strategy, Policy & Information, World Health Organization, avenue Appia 20, 1211 Geneva 27, Switzerland.

Surveillance is central to public health. In the absence of comparable data from most low-income and middle-income countries, national and international agencies use estimates to monitor health targets. Although morbidity and mortality estimations generated by statistical modelling can fulfill national and global reporting requirements, locally generated data are needed to guide evidence-based local action. Read More

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December 2018

Medication belief as correlate of medication adherence among patients with diabetes in Edo State, Nigeria.

Nurs Open 2019 Jan 14;6(1):197-202. Epub 2018 Sep 14.

Department of Nursing Babcock University Ilisha Remo Ogun State Nigeria.

Aim: The study aim was to determine the level of medication adherence, patient medication belief and to determine the correlation between medication belief and medication adherence among patients with diabetes. This is to find out whether medication belief of patient could enhance medication adherence which in turn would promote effective management of diabetic mellitus in Nigeria.

Background: The World Health Organization (WHO, 2015) estimated that over 366 million people are affected. Read More

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January 2019

Gentle Is Better: The Original "Gentle Technique" for Fat Placement in Breast Lipofilling.

J Cutan Aesthet Surg 2018 Jul-Sep;11(3):120-126

Department of Plastic and Reconstructive Surgery, University of Rome "Tor Vergata," Rome, Italy.

Context: Breast lipofilling usually involves three different stages (harvesting, processing, and placement), and in each of these phases, adipocyte cells can be damaged. Our technique of fat placement is quite different from the others as we focus our attention on the last stage of fat graft procedure, which could explain the better results in graft survival.

Aims: Our method is focused on eliminating any unnecessary manipulation of the graft so as to optimize graft retention and clinical outcomes: Controlled movement and slow rate of fat injection are the cornerstone of our technique and guarantee a nontraumatic fat transfer and a greater survival rate of adipocytes. Read More

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December 2018

Nuclear Medicine in India: A Historical Journey.

Indian J Nucl Med 2018 Nov;33(Suppl 1):S5-S10

Department of Nuclear Medicine, Kokilaben Dhirubhai Ambani Hospital, Mumbai, Maharashtra, India.

Evidence-based historical accounts of critical events, which shaped nuclear medicine in India today, are presented in this article. There was parallel activity happening in the northern and western region of India in the early 60s. Radiation Medicine Center (RMC) at Mumbai inaugurated in September 1963 by Dr. Read More

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November 2018

Registration and Outcome-Reporting Bias in Randomized Controlled Trials of Distal Radial Fracture Treatment.

JB JS Open Access 2018 Sep 24;3(3):e0065. Epub 2018 Jul 24.

Department of Academic Orthopaedics, Trauma and Sports Medicine, University of Nottingham, Nottingham, United Kingdom.

Background: The purpose of the present study was to systematically evaluate the completeness of trial registration and the extent of outcome-reporting bias in modern randomized controlled trials (RCTs) relating to the treatment of distal radial fracture.

Methods: With use of 4 databases (PubMed, Cochrane CENTRAL, Embase, and PEDro), this systematic review identified all RCTs of distal radial fracture treatment published from January 1, 2010, to December 31, 2015. We independently determined the registration status of these trials in a public trial registry and compared the characteristics of registered and non-registered trials. Read More

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September 2018

Complex Interventions and Interorganisational Relationships: Examining Core Implementation Components of Assertive Community Treatment.

Int J Integr Care 2018 Dec 6;18(4):11. Epub 2018 Dec 6.

Department of Social Work, Umeå University, Umeå, SE.

Introduction: There is increasing interest in implementing evidence-based integrated models of care in community-based mental health service systems. Assertive Community Treatment (ACT) is seen as an attractive, and at the same time challenging, model to implement in sectored service settings. This study investigates the implementation process of such an initiative. Read More

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December 2018

Prevalence and treatment of hip and knee osteoarthritis in people aged 60 years or older in Germany: an analysis based on health insurance claims data.

Clin Interv Aging 2018 14;13:2339-2349. Epub 2018 Nov 14.

Department of Health Services Research, Carl von Ossietzky University, Oldenburg, Germany.

Objective: Osteoarthritis (OA) is highly prevalent throughout the world, especially in the elderly population, and is strongly associated with patients' frailty. However, little is known about the prevalence and treatment of OA in elderly patients in routine clinical care in Germany.

Materials And Methods: As a part of Linking Patient-Reported Outcomes with CLAIms Data for Health Services Research in Rheumatology (PROCLAIR), a cross-sectional study using claims data from a large Germany statutory health insurance (BARMER) was conducted. Read More

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November 2018

The DREAMS core package of interventions: A comprehensive approach to preventing HIV among adolescent girls and young women.

PLoS One 2018 7;13(12):e0208167. Epub 2018 Dec 7.

Office of the U.S. Global AIDS Coordinator and Health Diplomacy, U.S. Department of State, Washington, DC, United States of America.

In sub-Saharan Africa, adolescent girls and young women (AGYW) are 5 to 14 times more likely to be infected with HIV than their male peers. Every day, more than 750 AGYW are infected with HIV. Many factors make girls and young women particularly vulnerable to HIV, including gender-based violence, exclusion from economic opportunities, and a lack of access to secondary school. Read More

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December 2018

Low dose aspirin blocks breast cancer-induced cognitive impairment in mice.

PLoS One 2018 10;13(12):e0208593. Epub 2018 Dec 10.

Drug Discovery Biology Theme, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.

Cancer patients with non-central nervous system tumors often suffer from cognitive impairment. While chemotherapy has long been attributed as the cause of these memory, learning and concentration difficulties, we recently observed cognitive impairment in cancer patients prior to treatment. This suggests the cancer alone may be sufficient to induce cognitive impairment, however the mechanisms are unknown. Read More

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December 2018

Non-GVHD ocular complications after hematopoietic cell transplantation: expert review from the Late Effects and Quality of Life Working Committee of the CIBMTR and Transplant Complications Working Party of the EBMT.

Bone Marrow Transplant 2018 Dec 7. Epub 2018 Dec 7.

Department of Ophthalmology, Hospital Universitario Puerta de Hierro, Madrid, Spain.

Non-graft-vs.-host disease (non-GVHD) ocular complications are generally uncommon after hematopoietic cell transplantation (HCT), but can cause prolonged morbidity affecting activities of daily living and quality of life. Here we provide an expert review of non-GVHD ocular complications in a collaboration between transplant physicians and ophthalmologists through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Read More

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December 2018

Analysis of 51 proposed hypertrophic cardiomyopathy genes from genome sequencing data in sarcomere negative cases has negligible diagnostic yield.

Genet Med 2018 Dec 11. Epub 2018 Dec 11.

Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

Purpose: Increasing numbers of genes are being implicated in Mendelian disorders and incorporated into clinical test panels. However, lack of evidence supporting the gene-disease relationship can hinder interpretation. We explored the utility of testing 51 additional genes for hypertrophic cardiomyopathy (HCM), one of the most commonly tested Mendelian disorders. Read More

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December 2018

[Endotheliotropic effects of venotonic drugs in treatment of patients with varicose veins].

Angiol Sosud Khir 2018 ;24(4):72-74

Department of Cardiovascular, Roentgenoendovascular, Operative Surgery and Topographic Anatomy, Ryazan State Medical University named after Academician I.P. Pavlov under the RF Ministry of Public Health, Ryazan, Russia.

The authors analysed the effect of Venarus on the endothelial function in patients suffering from lower limb varicose veins. Our open-label prospective study included a total of 100 patients diagnosed as having CEAP class C1-C2 varicose veins and divided into two equal groups. Dynamic assessment of the clinical course of the disease in Group One patients was carried out on the background of taking Venarus and compression therapy, with Group Two patients evaluated without taking Venarus. Read More

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January 2018

Toward Evidence-Based Practice.

MCN Am J Matern Child Nurs 2019 Jan/Feb;44(1):56-58

Kathleen Leask Capitulo is Chief Nurse Executive, James J. Peters VA Medical Center, Bronx, NY. She is also an Editorial Board member of MCN. Dr. Capitulo can be reached via e-mail at Nancy O'Brien-Abel is a Perinatal Clinical Nurse Specialist, President of Perinatal Consulting, LLC, an Affiliate Instructor in Family and Child Nursing at the University of Washington, Seattle, WA, and an Editorial Board member of MCN. Ms. O'Brien-Abel can be reached via e-mail at

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December 2018

Symptom Care at Home: A Comprehensive and Pragmatic Pro System Approach to Improve Cancer Symptom Care.

Med Care 2018 Dec 10. Epub 2018 Dec 10.

University of Utah (emeritus), Salt Lake City, UT.

Introduction: There is growing recognition that systematically obtaining the patient's perspective on their health experience, using patient-reported outcomes (PRO), can be used to improve patient care in real time. Few PRO systems are designed to monitor and provide symptom management support between visits. Patients are instructed to contact providers between visits with their concerns, but they rarely do, leaving patients to cope with symptoms alone at home. Read More

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December 2018

Treating Chronic Nonmalignant Pain: Evidence and Faith-Based Approaches.

J Christ Nurs 2019 Jan/Mar;36(1):22-30

Sarah Snell, DNP, CRNA, teaches in the Department of Nurse Anesthesia, Adventist University of Health Sciences, Orlando, Florida. Tia Hughes, DrOT, is the program director for the occupational therapy program at Adventist University of Health Sciences. Carolyn Fore, PhD, RN, is a professor in the Department of Nursing at Adventist University of Health Sciences. Roy Lukman, PhD, is the director, Department of Institutional Research at Adventist University of Health Sciences. Brett Morgan, DNP, CRNA, is director of the Nurse Anesthesia Doctor of Nursing Practice Program, Duke University School of Nursing, Durham, North Carolina.

A significant portion of the world's population is impacted by chronic pain; in the United States, chronic pain costs billions annually in treatment and lost productivity. A needs assessment was conducted to evaluate the prevalence of chronic nonmalignant pain (CNMP) at a university occupational therapy clinic over a 3-month period; recommendations were made to improve pain management at the clinic and referring hospital system. Graded Chronic Pain Scale 2. Read More

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December 2018

Can a psychometric property be a qualitative measure in disguise?

Authors:
Michelle Block

JBI Database System Rev Implement Rep 2018 Dec;16(12):2246-2247

Associate Professor of Nursing, The Indiana Center for Evidence Based Nursing Practice: a Joanna Briggs Institute Center of Excellence.

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December 2018