7,164 results match your criteria Evidence-based Complementary and Alternative Medicine [Journal]


Screening Five Qi-Tonifying Herbs on M2 Phenotype Macrophages.

Evid Based Complement Alternat Med 2019 15;2019:9549315. Epub 2019 Jan 15.

Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Cailun Road 1200, Shanghai 201203, China.

Tumor-associated macrophages (TAMs) with M2 phenotype play an essential role in tumor microenvironment (TME) during the progression and development of numerous cancers and associated with poor prognosis. Thus, regulation of TAMs polarization emerged as a new strategy for tumor immune therapy. According to Traditional Chinese Medicine (TCM) theory, herbs with Qi-tonifying character are involved in improving the defense capacity of immune system. Read More

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http://dx.doi.org/10.1155/2019/9549315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350552PMC
January 2019

Auricular Plaster Therapy for Comorbid Insomnia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Evid Based Complement Alternat Med 2019 15;2019:7120169. Epub 2019 Jan 15.

School of Nursing, Tongji Medical College, Huazhong University of Science and Technology, Hangkong Road 13, Qiaokou District, Wuhan 430030, China.

Background: Although the effectiveness of auricular plaster therapy (APT) on primary insomnia has been systematically reviewed, no systematic review of studies has focused on the effect on comorbid insomnia.

Objective: To evaluate the efficacy and safety of APT for comorbid insomnia.

Methods: Fifteen databases were searched from inception to July 2018. Read More

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http://dx.doi.org/10.1155/2019/7120169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350581PMC
January 2019

Effect of Propolis Preparations on Transepithelial Electrical Potential, Resistance, and Ion Transport in Study.

Evid Based Complement Alternat Med 2019 15;2019:3756092. Epub 2019 Jan 15.

Department of Pathobiochemistry and Clinical Chemistry, Faculty of Pharmacy, Collegium Medicum in Bydgoszcz Nicolaus Copernicus University in Torun, Poland.

Background: Propolis and its ethanol extract show positive germicidal, bacteriostatic, and anti-inflammatory antioxidants and regenerative properties after use on the surface of the skin. Propolis is in common use in production of cosmetics and in folk medicine. The influence of this resinous mixture on ion channels, channels located in skin cells membranes and skin electrical resistance, was not explained. Read More

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http://dx.doi.org/10.1155/2019/3756092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350614PMC
January 2019

, , and Essential Oils: Chemical Composition, Antimicrobial and Antileishmanial Activity.

Evid Based Complement Alternat Med 2019 15;2019:2421695. Epub 2019 Jan 15.

Mestrado em Ciência Animal, Universidade Estadual do Maranhão, 65055-310 São Luís, MA, Brazil.

The resistance mechanisms of bacteria and protozoans have evidenced the need of discover new compounds with potential pharmaceutical activity against pathogenic microorganisms. Medicinal plants have been for centuries a promising alternative as sources of new drugs. The objective of this work was to evaluate the chemical composition, antimicrobial and antileishmanial activities of , , and essential oils. Read More

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http://dx.doi.org/10.1155/2019/2421695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350612PMC
January 2019

Lung Function Decline after 24 Weeks of Moxa Smoke Exposure in Rats.

Evid Based Complement Alternat Med 2019 10;2019:9236742. Epub 2019 Jan 10.

Beijing University of Chinese Medicine, Beijing, China.

Objective: Moxibustion is a complementary therapy that has been used for thousands of years. Burning moxa produces smoke and inhalable particulates. Recent research has indicated that smoke inhalation is associated with negative lung effects. Read More

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http://dx.doi.org/10.1155/2019/9236742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348917PMC
January 2019

Effects of Laser Acupuncture on Delayed Onset Muscle Soreness of the Biceps Brachii Muscle: A Randomized Controlled Trial.

Evid Based Complement Alternat Med 2019 13;2019:6568976. Epub 2019 Jan 13.

Department of Physical Therapy, China Medical University. No. 91, Hsueh-Shih Road, Taichung City 404, Taiwan.

Objectives: The aim of this study was to explore the effects of laser acupuncture on improvement of recovery and muscle performance in delayed muscle soreness (DOMS) when applied before exercise.

Methods: This randomized, blinded, and controlled study included healthy participants (n = 40) who were randomized into laser acupuncture and placebo groups. Laser acupuncture was applied to the Tianquan (PC2) and Chihtseh acupoints (LU5) at a dose of 36 J and energy density of 9. Read More

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http://dx.doi.org/10.1155/2019/6568976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348906PMC
January 2019

Aiweixin, a Traditional Uyghur Medicinal Formula, Extends the Lifespan of .

Evid Based Complement Alternat Med 2019 13;2019:3684601. Epub 2019 Jan 13.

College of Xinjiang Uyghur Medicine, Hetian, Xinjiang 848000, China.

Aiweixin (AWX) is a traditional Uyghur medicine prescription, which has been used to treat senile diseases for a long time. We investigate whether the AWX extends the lifespan of . The AWX decoction was the conventional product for clinical use. Read More

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http://dx.doi.org/10.1155/2019/3684601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348922PMC
January 2019

Corrigendum to "Cardioprotective Effects of Qishenyiqi Mediated by Angiotensin II Type 1 Receptor Blockade and Enhancing Angiotensin-Converting Enzyme 2".

Evid Based Complement Alternat Med 2019 10;2019:9791436. Epub 2019 Jan 10.

Beijing University of Chinese Medicine, Bei San Huan Dong Lu 11, Chao Yang District, Beijing 100029, China.

[This corrects the article DOI: 10.1155/2012/978127.]. Read More

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http://dx.doi.org/10.1155/2019/9791436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348833PMC
January 2019
1.880 Impact Factor

Downregulation of Aquaporin 3 Mediated the Laxative Effect in the Rat Colon by a Purified Resin Glycoside Fraction from Pharbitis Semen.

Evid Based Complement Alternat Med 2019 13;2019:9406342. Epub 2019 Jan 13.

Jiangsu Key Laboratory of Bioactive Natural Product Research and State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, China.

Background: Pharbitis Semen, the seeds of , is widely used as a traditional purgative medicine in China, Korea, and Japan. This study investigated the laxative effects of a purified resin glycoside fraction obtained in our previous study from Pharbitis Semen in vivo and in vitro.

Materials And Methods: After orally administering a purified resin glycoside fraction from Pharbitis Semen (RFP) to rats, the content of fecal water, AQP3, NF-B, COX-2 expression, and the prostaglandin E (PGE) concentrations in the colon were examined. Read More

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http://dx.doi.org/10.1155/2019/9406342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348868PMC
January 2019

Investigation of Safety Profile of Four Species and of Kaurenoic Acid by /Microsome Test.

Evid Based Complement Alternat Med 2019 10;2019:7631531. Epub 2019 Jan 10.

Laboratory of Research in Applied Microbiology (LAPEMA), University of Franca, Avenida Dr. Armando Salles de Oliveira 201, 14404-600 Franca, SP, Brazil.

Trees of the genus are native to the tropical regions of Latin America and Western Africa. sp is widely used as a popular medicine and it has various ethnopharmacological indications, including gonorrhea, bronchitis, asthma, skin ulcers, ulcers, sore throat, uterine infections, general inflammations, cancer, and leishmanioses. Kaurenoic acid is a naturally occurring diterpene found in and has been used as an anti-inflammatory, treatment of ulcer, leishmaniasis, and cancer. Read More

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http://dx.doi.org/10.1155/2019/7631531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348810PMC
January 2019
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The Influence of Carrier Oils on the Antimicrobial Activity and Cytotoxicity of Essential Oils.

Evid Based Complement Alternat Med 2019 14;2019:6981305. Epub 2019 Jan 14.

University of the Witwatersrand, Faculty of Health Sciences, Department of Pharmacy and Pharmacology, 7 York Road, Parktown 2193, South Africa.

The topical use of essential oils requires dilution into a carrier oil; however, scientific evidence regarding the antimicrobial efficacy and cytotoxicity when a carrier oil is combined with an essential oil is lacking. This study sets out to determine the antimicrobial activity and cytotoxicity of 23 essential oils combined with six known carrier oils. Gas chromatography-mass spectrometry/flame ionization detector (GC-MS/FID) was used to characterize the methyl esters of the carrier oils. Read More

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http://dx.doi.org/10.1155/2019/6981305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348851PMC
January 2019

Corrigendum to "A Comparison of Wound Healing Rate Following Treatment with Aftamed and Chlorine Dioxide Gels in Streptozotocin-Induced Diabetic Rats".

Evid Based Complement Alternat Med 2019 10;2019:4265081. Epub 2019 Jan 10.

Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia.

[This corrects the article DOI: 10.1155/2012/468764.]. Read More

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http://dx.doi.org/10.1155/2019/4265081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348817PMC
January 2019

Chinese Herbal Formula Feilin Vaginal Gel Prevents the Cervicitis in Mouse Model.

Evid Based Complement Alternat Med 2019 10;2019:4168126. Epub 2019 Jan 10.

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Cervicitis is a common sexually transmitted disease. In recent years, the abuse of antibiotic in the treatment of cervicitis results in the emergence of antibiotic-resistant bacteria; alternative strategies are needed to be developed. In this research, we investigated the effects of Feilin Vaginal Gel (FVG), a Chinese herbal formula, on the treatment of cervicitis. Read More

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http://dx.doi.org/10.1155/2019/4168126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348856PMC
January 2019

Safety Evaluation of a New Traditional Chinese Medical Formula, Ciji-Hua'ai-Baosheng II Formula, in Adult Rodent Models.

Evid Based Complement Alternat Med 2019 14;2019:3659890. Epub 2019 Jan 14.

Department of Traditional Chinese Medicine, School of Medicine, Xiamen University, Xiamen 361102, Fujian, China.

Background: Ciji-Hua'ai-Baosheng II Formula (CHB-II-F) is a new traditional Chinese medical formula that has been shown to reduce toxicity and side effects of chemotherapy and increase the probability of cancer patient survival. Whether CHB-II-F is safe as an adjunctive therapy for cancer patients receiving chemotherapy has yet to be determined.

Purpose: To evaluate the acute and subchronic toxic effects of CHB-II-F in rodent models. Read More

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http://dx.doi.org/10.1155/2019/3659890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348800PMC
January 2019
1 Read
1.880 Impact Factor

Corrigendum to "Antiadipogenic Effects of Extract: In Vivo and In Vitro Effects".

Evid Based Complement Alternat Med 2019 10;2019:2459192. Epub 2019 Jan 10.

Department of Pharmacology, College of Oriental Medicine, Sangji University, Wonju-si, Gangwon-do 220-702, Republic of Korea.

[This corrects the article DOI: 10.1155/2013/859624.]. Read More

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http://dx.doi.org/10.1155/2019/2459192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348843PMC
January 2019

Adenosine Attenuates LPS-Induced Cardiac Dysfunction by Inhibition of Mitochondrial Function via the ER Pathway.

Evid Based Complement Alternat Med 2019 10;2019:1832025. Epub 2019 Jan 10.

Henan University of Chinese Medicine, Zhengzhou 450046, China.

Sepsis is a life-threatening organ dysfunction syndrome with a high rate of mortality. It is caused by an abnormal immune response to infection, and the occurrence of sepsis-induced cardiomyopathy is the primary cause of death. The present study was designed to examine the effects of adenosine on lipopolysaccharide- (LPS-) induced cardiac anomalies and the underlying mechanisms involved. Read More

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http://dx.doi.org/10.1155/2019/1832025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348826PMC
January 2019

Pilose Antler Extracts (PAEs) Protect against Neurodegeneration in 6-OHDA-Induced Parkinson's Disease Rat Models.

Evid Based Complement Alternat Med 2019 8;2019:7276407. Epub 2019 Jan 8.

Experimental Research Center, China Academy of Chinese Medical Sciences, No. 16, Nanxiao Road, Dongzhimen, Beijing 100700, China.

Parkinson's disease (PD) is one of the most common neurodegenerative diseases worldwide. Although dopamine replacement therapy mitigates motor dysfunction in PD patients, there are no therapeutics that are currently available to reverse neuronal cell death in the substantia nigra pars compacta (SNc), which is the main region for dopamine loss in PD patients. The protein concentration of the Pilose antler extracts (PAEs) was estimated using the Bradford Protein Assay Kit. Read More

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http://dx.doi.org/10.1155/2019/7276407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341246PMC
January 2019
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The Effects of Safflower Yellow on Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Randomized, Controlled Clinical Trial.

Evid Based Complement Alternat Med 2019 8;2019:5952742. Epub 2019 Jan 8.

Department of Anaesthesiology, West China Hospital of Sichuan University, Chengdu 610041, China.

Objectives: To evaluate the efficacy of safflower yellow in the acute exacerbation of chronic obstructive pulmonary disease (AECOPD).

Methods: In a prospective, randomized, controlled trial, 127 patients who met the inclusion criteria were enrolled and were randomly divided into two groups. The control group included 64 patients treated according to the global strategy for diagnosis, management, and prevention of COPD (www. Read More

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http://dx.doi.org/10.1155/2019/5952742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341243PMC
January 2019
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Effects of Compression Tights on Recovery Parameters after Exercise Induced Muscle Damage: A Randomized Controlled Crossover Study.

Evid Based Complement Alternat Med 2019 8;2019:5698460. Epub 2019 Jan 8.

Institute of Medical Physics, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), Erlangen, Germany.

Introduction: Recent meta-analyses on compression garments have reported faster recovery of muscle function particularly after intense eccentric power or resistance exercise. However, due to the complex interaction between cohorts included, exercises involved and compression applied, recovery length and modalities, and outcome parameters selected, only limited practical recommendations can be drawn from these studies. Thus, our aim was to determine the effect of compression tights on recovery from high mechanical and metabolic stress monitored over a longer recovery period. Read More

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http://dx.doi.org/10.1155/2019/5698460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341249PMC
January 2019
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Estrogenic Effect of the Extract of QingYan Formula on Reproductive Tissues in Immature Mice.

Evid Based Complement Alternat Med 2019 8;2019:5493714. Epub 2019 Jan 8.

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, China.

A Chinese herbal preparation, QingYan formula (QYF), has been used clinically for kidney-invigorating. However, no evidence base links QYF to estrogen replacement therapy. In this study, the estrogenic effects of QingYan formula 70% ethanol extract (QYFE) were investigated in immature mice. Read More

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http://dx.doi.org/10.1155/2019/5493714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341256PMC
January 2019

Protective Effects of Siebold Fruit Extract against Palmitate-Induced Lipotoxicity in Mesangial Cells.

Evid Based Complement Alternat Med 2019 8;2019:4509403. Epub 2019 Jan 8.

Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon 21999, Republic of Korea.

Diabetic nephropathy is one of the most serious complications of diabetes. Lipotoxicity in glomerular mesangial cells is associated with the progression of diabetic nephropathy. Paper mulberry, Siebold (BK), has been used in oriental medicine for human health problems. Read More

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http://dx.doi.org/10.1155/2019/4509403DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341277PMC
January 2019
1 Read

A Randomized, Controlled Clinical Trial of Combining Therapy with Traditional Chinese Medicine-Based Psychotherapy and Chinese Herbal Medicine for Menopausal Women with Moderate to Serious Mood Disorder.

Evid Based Complement Alternat Med 2019 6;2019:9581087. Epub 2019 Jan 6.

Department of Gynecology, The Second Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China.

Objective: To comparatively examine the effectiveness and safety of the combination therapy of traditional Chinese medicine formula Bushen-Shugan granule and psychotherapy (BSSG-P) and Chinese herbal medicine Bushen-Shugan granule (BSSG) alone in the treatment of moderate to serious mood disorder in menopausal women.

Methods: In our previous clinical studies, BSSG-P had been proved to be superior to BSSG, psychological treatment, and placebo in improving mild mood disorder in menopausal women. In this study, we analyzed the efficacy of BSSG-P and BSSG in the treatment of moderate to serious mood disorder. Read More

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http://dx.doi.org/10.1155/2019/9581087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339727PMC
January 2019
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Chromatography Based Metabolomics and Screening of Leaf Extract for Its Antidiabetic Potential.

Evid Based Complement Alternat Med 2019 6;2019:7523159. Epub 2019 Jan 6.

Human Genetics Laboratory, Department of Bioscience, Jamia Millia Islamia, New Delhi 110025, India.

, popularly known as gurmar, is extensively used in traditional systems of medicine for diabetes, stomach ailments, liver diseases, and cardiac disorders. Dried leaf powder of was extracted through soxhlation using 70% (v/v) alcohol. The hydroalcoholic extract was concentrated to 1/4th of its volume and basified to isolate gymnemic acid enriched extract using chloroform. Read More

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https://www.hindawi.com/journals/ecam/2019/7523159/
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http://dx.doi.org/10.1155/2019/7523159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339760PMC
January 2019
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Do Different Species of in Haizao Yuhu Decoction Cause Different Effects in a Rat Goiter Model?

Evid Based Complement Alternat Med 2019 6;2019:5645620. Epub 2019 Jan 6.

Beijing University of Chinese Medicine, No. 11 East Road, North 3rd Ring Road, Chaoyang District, Beijing 100029, China.

species combined with is a famous herbal pair in traditional Chinese medicine, as one of the so-called "eighteen antagonistic medicaments." In the Chinese Pharmacopoeia, two different species of , and , are recorded but they are not clearly differentiated in clinical use. In this study, we aimed to determine whether the two species of could result in different effects when combined with in Haizao Yuhu Decoction (HYD), which is used for treating thyroid-related diseases, especially goiter. Read More

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http://dx.doi.org/10.1155/2019/5645620DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339761PMC
January 2019
1 Read
1.880 Impact Factor

Plant Diversity and Ethnoveterinary Practices of Ethiopia: A Systematic Review.

Evid Based Complement Alternat Med 2019 6;2019:5276824. Epub 2019 Jan 6.

College of Agriculture and Natural resources, Wolkite University, Wolkite, Ethiopia.

The systematic review was conducted on Ethnoveterinary Medicinal (EVM) plants from the two (integrated and pastoral) majorly known livestock production systems (LPS) of Ethiopia. A total of 48 documents pertinent to EVM significance were assessed from different sources using Google search engine and local university websites. Search outputs were screened using the developed inclusion criteria, and only 26 documents were selected. Read More

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http://dx.doi.org/10.1155/2019/5276824DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339719PMC
January 2019

Clinical Effects and Safety of Tongxieyaofang on Diarrhea Predominant Irritable Bowel Syndrome: A Meta-Analysis of Randomized Trails.

Evid Based Complement Alternat Med 2019 6;2019:4893876. Epub 2019 Jan 6.

Department of Pathology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China.

Tongxieyaofang (TXYF), a prescription originated from traditional Chinese medicine (TCM), has been widely used on treating Diarrhea Predominant Irritable Bowel Syndrome (IBS-D). The purpose of this meta-analysis was to investigate whether TXYF was effective and safe for IBS-D. We searched seven electronic databases including CENTRAL, MEDLINE, PubMed, CNKI, VIP, CBM, and Wanfang Data up to 26 July 2017. Read More

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http://dx.doi.org/10.1155/2019/4893876DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339716PMC
January 2019

Antihypertensive Activity of Sw. (Poaceae) Aqueous Extract on Ethanol-Induced Hypertension in Wistar Rat.

Evid Based Complement Alternat Med 2019 6;2019:2897867. Epub 2019 Jan 6.

Department of Animal Biology and Physiology, Laboratory of Animal Physiology, University of Yaoundé I, P.O. Box 812, Yaoundé, Cameroon.

() is used in traditional medicine to treat many diseases including hypertension. This study aimed to evaluate the curative effects of the aqueous extract of on hypertension. Hypertension was induced in rats by oral administration of ethanol (5 g/kg/day) for five weeks. Read More

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http://dx.doi.org/10.1155/2019/2897867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339736PMC
January 2019

Natural Killer Response and Lipo-Metabolic Profile in Adults with Low HDL-Cholesterol and Mild Hypercholesterolemia: Beneficial Effects of Artichoke Leaf Extract Supplementation.

Evid Based Complement Alternat Med 2019 6;2019:2069701. Epub 2019 Jan 6.

Department of Brain and Behavioral Science, University of Pavia, Pavia, Italy.

The aim of the present study is to evaluate the effects of 60-day artichoke leaf extract (ALE) supplementation (250mg, twice daily) on cytokines levels, natural killer cell (NK) response, and lipo-metabolic profile (HDL, LDL, and total-cholesterol, triglycerides (TG), ApoB, ApoA, lipid accumulation product (LAP), glucose, insulin, and homeostasis model assessment of insulin resistance (HOMA-IR)) in twenty adults (9/11 males/females, age=49.10 ± 13.74 years, and BMI=33. Read More

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http://dx.doi.org/10.1155/2019/2069701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339758PMC
January 2019

Network Pharmacology Integrated Molecular Docking Reveals the Antiosteosarcoma Mechanism of Biochanin A.

Evid Based Complement Alternat Med 2019 6;2019:1410495. Epub 2019 Jan 6.

Department of Orthopedics, No. 371 Central Hospital of PLA, Xinxiang, Henan, China.

Background: As the malignant tumor with the highest incidence in teenagers, osteosarcoma has become a major problem in oncology research. In addition to surgical management, the pharmacotherapeutic strategy for osteosarcoma treatment is an attractive way to explore. It has been demonstrated that biochanin A has an antitumor capacity on multiple kinds of solid tumor, including osteosarcoma. Read More

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http://dx.doi.org/10.1155/2019/1410495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339762PMC
January 2019

Bufei Jianpi Granules Reduce Quadriceps Muscular Cell Apoptosis by Improving Mitochondrial Function in Rats with Chronic Obstructive Pulmonary Disease.

Evid Based Complement Alternat Med 2019 6;2019:1216305. Epub 2019 Jan 6.

Henan Key Laboratory of Chinese Medicine for Respiratory Disease, Henan University of Chinese Medicine, Zhengzhou, Henan 450046, China.

Background: Cell apoptosis is an important mechanism underlying skeletal muscle dysfunction in chronic obstructive pulmonary disease (COPD) patients, and mitochondrial dysfunction is recognized as a central aspect contributing to skeletal muscle deterioration. Bufei Jianpi granules have been confirmed effective for improving motor function in COPD patients, but the specific mechanism for this improved function remains unknown. This study explored the mechanisms by which Bufei Jianpi granules improve cell apoptosis and mitochondrial dysfunction in COPD. Read More

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http://dx.doi.org/10.1155/2019/1216305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339712PMC
January 2019

Antiproliferative and Proapoptotic Effects of a Protein Component Purified from Dallas on Cancer Cells and .

Evid Based Complement Alternat Med 2019 3;2019:8934794. Epub 2019 Jan 3.

Provincial Key Laboratory for Agricultural Pest Management of Mountainous Region, Institute of Entomology, Guizhou University, Guiyang, Guizhou 550025, China.

Dallas is used as a traditional Chinese medicine. In China, clinical evidence suggests that it has anticancer activity. However, the anticancer active components are not fully elucidated. Read More

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http://dx.doi.org/10.1155/2019/8934794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335791PMC
January 2019
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Treatment Effects of Jinlingzi Powder and Its Extractive Components on Gastric Ulcer Induced by Acetic Acid in Rats.

Evid Based Complement Alternat Med 2019 3;2019:7365841. Epub 2019 Jan 3.

School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, 24 Heping Road, Harbin, 150040, China.

Jinlingzi powder comprises . and and is usually applied in clinic as traditional Chinese medicine for pain. The present study aims to investigate the therapeutic actions of Jinlingzi powder and its extracted components and theirs treatment mechanism on the acetic acid induced-gastric ulcer in rats. Read More

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http://dx.doi.org/10.1155/2019/7365841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335817PMC
January 2019
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A Review of Antiplatelet Activity of Traditional Medicinal Herbs on Integrative Medicine Studies.

Evid Based Complement Alternat Med 2019 3;2019:7125162. Epub 2019 Jan 3.

Korean Medicine (KM)-Application Center, Korea Institute of Oriental Medicine (KIOM), 70 Cheomdan-ro, Dong-gu, Daegu 41062, Republic of Korea.

Thrombotic events mainly occurred by platelet activation and aggregation. The vascular occlusion causes serious disease states such as unstable angina, ischemic stroke, and heart attack. Due to the pervading of thrombotic diseases, new antiplatelet drugs are necessary for preventing and treating arterial thrombosis without adverse side effects. Read More

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http://dx.doi.org/10.1155/2019/7125162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335729PMC
January 2019
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Moxibustion of Zusanli (ST36) and Shenshu (BL23) Alleviates Cartilage Degradation through RANKL/OPG Signaling in a Rabbit Model of Rheumatoid Arthritis.

Evid Based Complement Alternat Med 2019 3;2019:6436420. Epub 2019 Jan 3.

Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.

Rheumatoid arthritis (RA) is a systemic and chronic autoimmune inflammatory disease characterized by severe synovial hyperplasia associated with progressive cartilage degradation. Due to the severe pain and disability caused by RA, effective therapeutic strategies that could simultaneously alleviate the inflammatory response and delay the disease progression are urgently needed. As a major alternative therapy in traditional Chinese medicine, moxibustion has been demonstrated that it could reduce the chronic inflammatory responses of a series of musculoskeletal diseases; however, whether moxibustion has protective effects on RA is still unclear. Read More

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http://dx.doi.org/10.1155/2019/6436420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335855PMC
January 2019
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Potential Therapeutic Effects of Underground Parts of on Benign Prostatic Hyperplasia.

Evid Based Complement Alternat Med 2019 2;2019:6340757. Epub 2019 Jan 2.

Instituto de Pesquisas de Produtos Naturais, Universidade Federal do Rio de Janeiro, 21941-902 Rio de Janeiro, RJ, Brazil.

Benign Prostatic Hyperplasia (BPH) affects mainly older men. It is estimated to affect 50% of 51-60-year-old men and 70% of 61-70-year-old men. BPH is a nonmalignant proliferation of epithelial and stromal cells of the prostate gland regions. Read More

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http://dx.doi.org/10.1155/2019/6340757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334319PMC
January 2019

Effects of on ATP, Na/K-ATPase, and Respiratory Chain Complexes of Hippocampus and Gastrocnemius Muscle in Depressed Rats.

Evid Based Complement Alternat Med 2019 3;2019:6054926. Epub 2019 Jan 3.

Dongfang Hospital Beijing University of Chinese Medicine, Beijing 100078, China.

Objective: To clarify the effectiveness and mechanism of the Chinese herbal formula (XPKYF) which is composed of (Xi-Yang-shen), (Yu-Jin), (Shi-Chang-pu), and (Guan-Ye-lian-qiao) in depressed rats.

Methods: The rat model of depression was established by chronic unpredictable mild stress (CUMS) method for 6 weeks. Rats were randomly divided into six groups: control group, CUMS group, CUMS+XPKYF (3. Read More

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http://dx.doi.org/10.1155/2019/6054926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335795PMC
January 2019

Different Brain Activation after Acupuncture at Combined Acupoints and Single Acupoint in Hypertension Patients: An Rs-fMRI Study Based on ReHo Analysis.

Evid Based Complement Alternat Med 2019 3;2019:5262896. Epub 2019 Jan 3.

School of Traditional Chinese Medicine, Southern Medical University, Guangzhou, Guangdong Province 510515, China.

Background: Acupuncture is proved to be effective on hypertension by numerous studies and resting-state functional magnetic resonance imaging (Rs-fMRI) is a widely used technique to study its mechanism. Along with lower blood pressure, patients with hypertension receiving acupuncture also presented improvement in function of cognition, emotion, language, sematic sensation, and so on. This study was a primary study to explore the acting path of acupuncture at combined acupoints in stimulated brain areas related to such functions. Read More

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http://dx.doi.org/10.1155/2019/5262896DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335668PMC
January 2019
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Acupuncture Enhances Communication between Cortices with Damaged White Matters in Poststroke Motor Impairment.

Evid Based Complement Alternat Med 2019 2;2019:4245753. Epub 2019 Jan 2.

Department of Neurology and Stroke Center, Dongzhimen Hospital, The First Affiliated Hospital of Beijing University of Chinese Medicine, Beijing, China.

Stroke is a leading cause of motor disability. Acupuncture is an effective therapeutic strategy for poststroke motor impairment. However, its mechanism is still elusive. Read More

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http://dx.doi.org/10.1155/2019/4245753DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334314PMC
January 2019
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Endothelium-Dependent Effects of (Cham. & Schltdl.) Micheli Mediated by M3-Muscarinic and B2-Bradykininergic Receptors on Peripheral Vascular Resistance and Its Modulatory Effects on K+ Channels in Mesenteric Vascular Beds.

Evid Based Complement Alternat Med 2019 2;2019:4109810. Epub 2019 Jan 2.

Faculdade de Ciências da Saúde, Universidade Federal da Grande Dourados, Dourados, MS, Brazil.

This work provides the first demonstration that ethanolic extract (EEEG) obtained from leaves (EEEG) and its butanolic fraction (ButFr) has important vasodilatory effects on isolated mesenteric vascular beds (MVBs). First, the EEEG was obtained and a liquid-liquid fractionation was performed. EEEG and its resulting fractions were analyzed by high-performance liquid chromatography. Read More

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http://dx.doi.org/10.1155/2019/4109810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334330PMC
January 2019

Yangyin Yiqi Mixture Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Rats through Inhibiting TGF-β1/Smad Pathway and Epithelial to Mesenchymal Transition.

Evid Based Complement Alternat Med 2019 3;2019:2710509. Epub 2019 Jan 3.

Beijing University of Chinese Medicine, No. 11 on North 3rd Ring Road, Beijing 100029, China.

Objective: The aim of the current study was to investigate the protective effect of Yangyin Yiqi Mixture (YYYQ) on Bleomycin-induced pulmonary fibrosis in rats based on TGF-1/Smad signal pathway and epithelial to mesenchymal transition (EMT).

Methods: 120 Wistar rats were randomly divided into six groups: control group, BLM group, BLM + Pred group, BLM+YYYQ-L group, BLM+YYYQ-M group, and BLM+YYYQ-H group. Rats were given an intratracheal instillation of 3 mg/kg BLM to establish the pulmonary fibrosis model and followed by different dosages of YYYQ (11, 22, 44g/kg, via intragastric gavage) or prednisone soluble (4. Read More

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http://dx.doi.org/10.1155/2019/2710509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335662PMC
January 2019

Systematically Characterizing Chemical Profile and Potential Mechanisms of Qingre Lidan Decoction Acting on Cholelithiasis by Integrating UHPLC-QTOF-MS and Network Target Analysis.

Evid Based Complement Alternat Med 2019 3;2019:2675287. Epub 2019 Jan 3.

Institute of Integrative Medicine, Dalian Medical University, No. 9, South Road of Lvshun, Dalian 116044, China.

Qingre Lidan Decoction (QRLDD), a classic precompounded prescription, is widely used as an effective treatment for cholelithiasis clinically. However, its chemical profile and mechanism have not been characterized and elucidated. In the present study, a rapid, sensitive, and reliable ultraperformance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry method was established for comprehensively identifying the major constituents in QRLDD. Read More

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http://dx.doi.org/10.1155/2019/2675287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335670PMC
January 2019
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Investigation on Advanced Non-Small-Cell Lung Cancer among Elderly Patients Treated with Chinese Herbal Medicine versus Chemotherapy: A Pooled Analysis of Individual Data.

Evid Based Complement Alternat Med 2019 2;2019:1898345. Epub 2019 Jan 2.

Integrative Cancer Centre, Guangzhou University of Chinese Medicine First Affiliated Hospital, Guangzhou, Guangdong, China.

Purpose: Many patients with advanced non-small-cell lung cancer (NSCLC) seek help from Chinese herbal medicine (CHM). The purpose of this study was to investigate the survival between CHM and chemotherapy (CT) treatment of patients aged ≥60 years with advanced Epidermal Growth Factor Receptor (EGFR) wild type NSCLC and Karnofsky Performance Status (KPS) ≥ 60.

Methods: We extracted individual data of all eligible patients from 1 randomized control trial and 2 cohort studies and performed a pooled analysis. Read More

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http://dx.doi.org/10.1155/2019/1898345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334362PMC
January 2019
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Effects of Shugan Hewei Granule on Depressive Behavior and Protein Expression Related to Visceral Sensitivity in a Rat Model of Nonerosive Reflux Disease.

Evid Based Complement Alternat Med 2019 2;2019:1505693. Epub 2019 Jan 2.

Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Objective: To explore the effect of Shugan Hewei Granule (SGHWG) and to provide the experimental basis for its clinical application.

Methods: 40 healthy male Wistar rats were divided into 5 groups, with 8 rats in each group, including control group, model group, normal saline (NS) group, SGHWG group, and Rabeprazole group. The control group was not treated. Read More

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http://dx.doi.org/10.1155/2019/1505693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334618PMC
January 2019

A Review on the Nonpharmacological Therapy of Traditional Chinese Medicine with Antihypertensive Effects.

Evid Based Complement Alternat Med 2019 2;2019:1317842. Epub 2019 Jan 2.

Longhua Hospital, Shanghai University of Traditional Chinese Medicine, China.

Hypertension is a global health concern. Although the pharmacological treatment has obvious antihypertensive effects, there are still some limitations on management of hypertension by drug therapy alone. In recent years, the nonpharmacological therapy of traditional Chinese medicine (TCM) has gradually become an important mean to help the prevention and treatment of hypertension in some Eastern countries. Read More

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https://www.hindawi.com/journals/ecam/2019/1317842/
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http://dx.doi.org/10.1155/2019/1317842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334369PMC
January 2019
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Effectiveness of Extract Combination with Atorvastatin on Experimentally Induced Hyperlipidemia in Rats.

Evid Based Complement Alternat Med 2019 1;2019:9726137. Epub 2019 Jan 1.

Professor of Physiology, Zoology Department, Faculty of Science, Cairo University, Egypt.

Background: The present study aimed to assess the effectiveness of clam extract in combination with atorvastatin against experimentally hyperlipidemia in rats.

Method: Forty male rats were divided into 5 groups (8 rats /group): control, high fat diet (HFD), atorvastatin (AROR), clam extract (CE), and ATOR + CE.

Results: The treatments with ATOR and /or CE significantly reduced the body weight gain, AST, ALT, ALP, TL, TC, TG, LDL-C, urea, creatinine, and uric acid levels while they increased total proteins, albumin, and HDL-C. Read More

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http://dx.doi.org/10.1155/2019/9726137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332942PMC
January 2019

Huangqi-Danshen Decoction Ameliorates Adenine-Induced Chronic Kidney Disease by Modulating Mitochondrial Dynamics.

Evid Based Complement Alternat Med 2019 1;2019:9574045. Epub 2019 Jan 1.

Department of Nephrology, Shenzhen Traditional Chinese Medicine Hospital, Guangzhou University of Chinese Medicine, Shenzhen, Guangdong, China.

Chronic kidney disease (CKD) is a leading public health problem with high morbidity and mortality. However, the therapies remain limited. Traditional Chinese medicine (TCM) has been used for treating kidney disease for thousands of years and is an effective alternative treatment for CKD patients in China and other Asian countries. Read More

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http://dx.doi.org/10.1155/2019/9574045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332985PMC
January 2019

Circulating Hypoxia Responsive microRNAs (HRMs) and Wound Healing Potentials of Green Tea in Diabetic and Nondiabetic Rat Models.

Evid Based Complement Alternat Med 2019 1;2019:9019253. Epub 2019 Jan 1.

Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Green tea () has many biological activities and may promote diabetic wound healing by regulation of circulating hypoxia responsive microRNAs (HRMs) which triggers the wound repairing process in diabetic and nondiabetic wounds. Thus, in this study, the potential effects of green tea extract (GTE) on the expression of miRNAs; miR-424, miR-199a, miR-210, miR-21, and fibrogenitic markers; hydroxyproline (HPX), fibronectin (FN), and nitric oxide (NO) were evaluated in wounds of diabetic and nondiabetic rats. The animals were topically treated with vaseline, 0. Read More

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http://dx.doi.org/10.1155/2019/9019253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332961PMC
January 2019

Ethnomedical Survey of the Plants Used by Traditional Healers in Narok County, Kenya.

Evid Based Complement Alternat Med 2019 1;2019:8976937. Epub 2019 Jan 1.

Department of Forestry, University of Eldoret, P.O. Box 1125-30100, Eldoret, Kenya.

Most of the plants used by herbalists amongst the various Kenyan communities have not been documented despite their widespread use. The purpose of this research was to document the medicinal plants used by the herbalists from the Maasai, a community that still relies on herbal medicine to a large extent for the provision of medical services. Semistructured interviews, direct observations, group discussions, and in-depth interviews were used to collect information from the traditional healers. Read More

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https://www.hindawi.com/journals/ecam/2019/8976937/
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http://dx.doi.org/10.1155/2019/8976937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332960PMC
January 2019
2 Reads
1.880 Impact Factor

Tetrandrine-Induced Autophagy in MDA-MB-231 Triple-Negative Breast Cancer Cell through the Inhibition of PI3K/AKT/mTOR Signaling.

Evid Based Complement Alternat Med 2019 1;2019:7517431. Epub 2019 Jan 1.

The Fangshan Hospital, Beijing University of Chinese Medicine, Beijing 102488, China.

The present study examined the effects of tetrandrine suppressing proliferation, targeting LC3, p62, and Beclin-1 autophagy genes by inhibiting PI3K/AKT/mTOR signaling in Triple-negative breast cancer (TNBC) MDA-MB-231 cell. Cell viability and apoptosis were evaluated by MTT and Annexin-V/PI double staining. Cytotoxicity was determined with LDH assay. Read More

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https://www.hindawi.com/journals/ecam/2019/7517431/
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http://dx.doi.org/10.1155/2019/7517431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332987PMC
January 2019
9 Reads