158,163 results match your criteria Evidence-based Complementary and Alternative Medicine [Journal]


2018 Infectious Diseases Society of America Clinical Practice Guideline for the Management of Outpatient Parenteral Antimicrobial Therapy.

Clin Infect Dis 2019 Jan;68(1):1-4

Department of Medicine, Perelman School of Medicine, University of Pennsylvania, and Center for Evidence-based Practice, University of Pennsylvania Health System, Philadelphia.

A panel of experts was convened by the Infectious Diseases Society of America to update the 2004 clinical practice guideline on outpatient parenteral antimicrobial therapy (OPAT) [1]. This guideline is intended to provide insight for healthcare professionals who prescribe and oversee the provision of OPAT. It considers various patient features, infusion catheter issues, monitoring questions, and antimicrobial stewardship concerns. Read More

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January 2019

Mobilising evidence to improve nursing practice: A qualitative study of leadership roles and processes in four countries.

Int J Nurs Stud 2018 Nov 27;90:21-30. Epub 2018 Nov 27.

School of Education, Health, and Social Studies, Dalarna University, Falun, Sweden.

Background: The approach and style of leaders is known to be an important factor influencing the translation of research evidence into nursing practice. However, questions remain as to what types of roles are most effective and the specific mechanisms through which influence is achieved.

Objectives: The aim of the study was to enhance understanding of the mechanisms by which key nursing roles lead the implementation of evidence-based practice across different care settings and countries and the contextual factors that influence them. Read More

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November 2018

Estimating the probability of abusive head trauma after abuse evaluation.

Child Abuse Negl 2018 Dec 11;88:266-274. Epub 2018 Dec 11.

Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, United States.

Background: Evidence-based, patient-specific estimates of abusive head trauma probability can inform physicians' decisions to evaluate, confirm, exclude, and/or report suspected child abuse.

Objective: To derive a clinical prediction rule for pediatric abusive head trauma that incorporates the (positive or negative) predictive contributions of patients' completed skeletal surveys and retinal exams.

Participants And Setting: 500 acutely head-injured children under three years of age hospitalized for intensive care at one of 18 sites between 2010 and 2013. Read More

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December 2018

National survey: Developing a common approach to grading of practice in pre-registration midwifery.

Nurse Educ Pract 2018 Nov 26;34:150-160. Epub 2018 Nov 26.

University College London, Gower St, Bloomsbury, London, WC1E 6BT, United Kingdom. Electronic address:

This paper presents the final phase of a national project exploring grading of practice in programmes leading to registration as a midwife in the United Kingdom. The aim was to develop a generic framework for grading practice, enhancing standardisation while enabling flexibility in application of current and new educational standards. A mixed method on-line survey considered existing practice assessment tools, factors contributing to robust and reliable assessment and perceptions of two assessment tools developed by the research team: a 'Lexicon Framework' and 'Rubric', which were tested through scenarios. Read More

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November 2018

Which patients initiate cognitive processing therapy and prolonged exposure in department of veterans affairs PTSD clinics?

J Anxiety Disord 2018 Nov 20;62:53-60. Epub 2018 Nov 20.

Center for Chronic Disease Outcomes Research, Minneapolis VA Health Care System, One Veterans Drive, Minneapolis, MN 55417, USA; Department of Medicine, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455, USA; Department of Psychiatry, University of Minnesota, 2450 Riverside Ave, Minneapolis, MN 55454, USA; Department of Psychology, University of Minnesota, 75 E River Rd, Minneapolis, MN 55455, USA. Electronic address:

The United States Department of Veterans Affairs (VA) provides Cognitive Processing Therapy (CPT) and Prolonged Exposure therapy (PE) for PTSD at all of its facilities, but little is known about systematic differences between patients who do and do not initiate these treatments. VA administrative data were analyzed for 6,251 veterans receiving psychotherapy over one year in posttraumatic stress disorder (PTSD) specialty clinics at nine VA medical centers. CPT and PE were initiated by 2,173 (35%) patients. Read More

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November 2018

International priorities for home care education, research, practice, and management: Qualitative content analysis.

Nurse Educ Today 2018 Dec 7;73:83-87. Epub 2018 Dec 7.

Case Western Reserve University, United States of America. Electronic address:

Background: Despite growing demand for home care nursing, there is a growing home care workforce shortage, due in part to hospital-centric nursing curricula that lead students to undervalue of home care and community practice setting (Van Iersel et al., 2018a, 2018b).

Objectives: Articulate an international vision for the future of home care education, research, practice, and management shared by experienced home care nurses working in leadership roles. Read More

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December 2018

Current Resources for Evidence-Based Practice, January 2019.

Authors:
Marit L Bovbjerg

J Obstet Gynecol Neonatal Nurs 2018 Dec 11. Epub 2018 Dec 11.

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December 2018

One-Session Treatment of Phobias in Children: Recent Developments and a Systematic Review.

Annu Rev Clin Psychol 2018 Dec 14. Epub 2018 Dec 14.

Department of Psychology, Stockholm University, SE-106 91 Stockholm, Sweden; email:

One-session treatment is a well-established evidence-based treatment for specific phobias in youths that incorporates reinforcement, cognitive challenges, participant modeling, psychoeducation, and skills training into a single, massed session of graduated exposure. This review begins by briefly examining the phenomenology, etiology, epidemiology, and assessment of specific phobias and then pivots to a description of One-Session Treatment. We examine the use of One-Session Treatment with children and adolescents, briefly discussing its components and application, and subsequently review almost two decades of research supporting its efficacy. Read More

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December 2018

Impact of Patient Safety Culture on Missed Nursing Care and Adverse Patient Events.

J Nurs Care Qual 2018 Dec 12. Epub 2018 Dec 12.

Columbia University, School of Nursing, New York, New York (Dr Hessels); Ann May Center for Nursing and Allied Health, Hackensack Meridian Health, Neptune, New Jersey (Drs Hessels, Weaver, and Wurmser); Institute of Evidence-Based Care, Hackensack Meridian Health, Neptune, New Jersey (Ms Paliwal); and Medical Services Division, United Nations, New York, New York (Dr Siddiqui).

Background: A strong patient safety culture (PSC) may be associated with improved patient outcomes in hospitals. The mechanism that explains this relationship is underexplored; missed nursing care may be an important link.

Purpose: The purpose of this study was to describe relationships among PSC, missed nursing care, and 4 types of adverse patient events. Read More

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December 2018

High-grade Endometrial Carcinomas: Morphologic and Immunohistochemical Features, Diagnostic Challenges and Recommendations.

Int J Gynecol Pathol 2019 Jan;38 Suppl 1:S40-S63

Department of Pathology, Memorial Sloan Kettering Cancer Center (R.M., R.A.S.) New York University Medical Center and School of Medicine, Tisch Hospital (K.M.), New York Department of Pathology, University Hospital, Stony Brook School of Medicine, Stony Brook (C.T.), New York Department of Pathology, Oslo University Hospital, Norwegian Radium Hospital; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway (B.D.) Department of Pathology, University of California San Diego, San Diego (O.F.) Department of Pathology, Cedars-Sinai Medical Center, Los Angeles (J.K.L.R.), California Department of Pathology, Karolinska Institutet, Stockholm, Sweden (J.A.C.) Department of Pathology, Brigham and Women's Hospital, Harvard Medical School (C.P.C.) Department of Pathology, Massachussetts General Hospital, Harvard Medical School (E.O.), Boston, Massachussetts Department of Pathology, University of British Columbia, Vancouver (C.B.G., J.A.I.) Department of Laboratory Medicine, Pathology and Medical Genetics, Royal Jubilee Hospital, Victoria (J.A.I.), BC, Canada Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas (A.M.) Department of Pathology, Hospital University Arnau de Vilanova; and Department of Pathology, Hospital University de Bellvitge, IRBLLEIDA, IDIBELL, University of Lleida, CIBERONC, Barcelona, Spain (X.M.-G.) Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK (W.G.M.) Department of Pathology and Obstetrics and Gynecology, Yale School of Medicine and Yale School of Publich Health, New Haven, Connecticut (V.P.) Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland (P.N.S.) Department of Pathology, KEMH and School for Women's and Infants' Health, University of Western Australia, Perth, WA, Australia (C.J.R.S.).

This review of challenging diagnostic issues concerning high-grade endometrial carcinomas is derived from the authors' review of the literature followed by discussions at the Endometrial Cancer Workshop sponsored by the International Society of Gynecological Pathologists in 2016. Recommendations presented are evidence-based, insofar as this is possible, given that the levels of evidence are weak or moderate due to small sample sizes and nonuniform diagnostic criteria used in many studies. High-grade endometrioid carcinomas include FIGO grade 3 endometrioid carcinomas, serous carcinomas, clear cell carcinomas, undifferentiated carcinomas, and carcinosarcomas. Read More

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January 2019
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Society of Cardiovascular Anesthesiologists/European Association of Cardiothoracic Anaesthetists Practice Advisory for the Management of Perioperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery.

Anesth Analg 2019 Jan;128(1):33-42

Department of Perioperative Medicine, Barts Heart Centre, St Bartholomew's Hospital, London, United Kingdom.

Postoperative atrial fibrillation (poAF) is the most common adverse event after cardiac surgery and is associated with increased morbidity, mortality, and hospital and intensive care unit length of stay. Despite progressive improvements in overall cardiac surgical operative mortality and postoperative morbidity, the incidence of poAF has remained unchanged at 30%-50%. A number of evidence-based recommendations regarding the perioperative management of atrial fibrillation (AF) have been released from leading cardiovascular societies in recent years; however, it is unknown how closely these guidelines are being followed by medical practitioners. Read More

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January 2019

Effective But Not Adhered to: How Can We Improve Adherence to Evidence-Based Hamstring Injury Prevention in Amateur Football?

Clin J Sport Med 2018 Dec 13. Epub 2018 Dec 13.

Department of Rehabilitation, Physical Therapy Science and Sports, Rudolf Magnus Institute of Neurosciences, University Medical Center Utrecht, Utrecht, the Netherlands.

Objectives: To investigate adherence to a Nordic hamstring exercise (NHE) program in a real-world context of male amateur football, and the perceptions of end users (players) and intervention deliverers (coaches and medical staff) about adherence to this proven effective program.

Design: Retrospective cohort study.

Setting: Dutch amateur football. Read More

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December 2018

Can a smartphone App help manage wounds in primary care?

J Am Assoc Nurse Pract 2018 Dec 12. Epub 2018 Dec 12.

School of Nursing & Health Professions, University of San Francisco, San Francisco, California.

Background And Purpose: Although wound care guidelines are available for primary care providers, barriers to assessment and treatment remain. This article examines current evidence supporting wound management, wound guidelines, and provider comfort with wound management in primary care and discusses the need for improved training, education, and the development of a simplified approach to wound management in primary care.

Methods: This review of evidence examines knowledge of wound care, wound curriculum, and the current availability of guidelines for health care providers at the frontlines. Read More

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December 2018

Statewide implementation of child trauma-focused practices using the community-based learning collaborative model.

Psychol Serv 2018 Dec 13. Epub 2018 Dec 13.

Institute of Behavioral Science.

A significant number of youth in the United States experience traumatic events that substantially increase the risk of physical and behavioral health problems across the life span. This public health concern warrants concerted efforts to promote trauma-informed, evidence-based practices that facilitate recovery. Although youth-focused trauma-specific treatments exist, determining effective ways to disseminate and implement these services-so that they are available, accessible, and sustainable-poses an ongoing challenge. Read More

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December 2018

Underaddressed animal-welfare issues in conservation.

Conserv Biol 2018 Dec 14. Epub 2018 Dec 14.

College of Veterinary Medicine, School of Veter…cut the number of references to the best 3inary and Life Sciences, Murdoch University, 90 South St, Murdoch, WA 6160, Australia.

Much progress has been made improving animal welfare in conservation over the past two decades. However, several glaring knowledge gaps remain where animal welfare concerns exist but animal welfare studies have not been performed in politically sensitive contexts. We use examples from Australia to identify four such issues lacking meaningful analysis; the absence of animal welfare oversight for operations designated as "management" (as opposed to research), the lack of consideration for the animal welfare impacts of biological agents that are used to control invasive animals, the paucity of studies to examine the welfare of animals that are hunted recreationally, and the scarcity of studies to examine the animal welfare impacts associated with Indigenous wildlife use. Read More

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December 2018

No Easy Answers: Avoiding Potential Pitfalls of De-implementation.

Am J Community Psychol 2018 Dec 14. Epub 2018 Dec 14.

School of Social Work, Columbia University, New York, NY, USA.

In 2012, the Centers for Disease Control and Prevention (CDC) began to de-emphasize and de-implement multiple evidence-based HIV prevention practices that had been around for 20 years, thus changing the scope of implementation across the globe. The authors provide evidence how existing interventions (e.g. Read More

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December 2018

Preconception management of women with obesity: A systematic review.

Obes Rev 2018 Dec 13. Epub 2018 Dec 13.

Department of Medicine (Austin Health), University of Melbourne, Heidelberg Heights, Victoria, Australia.

The prevalence of women of child-bearing age with obesity continues to rise at an alarming rate. This has significant implications for both the short-term and long-term health of mother and offspring. Given the paucity of evidence-based literature in this field, the preconception management of women with obesity is highly variable both between institutions and around the world. Read More

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December 2018

A Systematic Review of Ayres Sensory Integration Intervention for Children with Autism.

Autism Res 2018 Dec 12. Epub 2018 Dec 12.

Department of Occupational Therapy Jefferson, College of Health Professions Faculty, Farber Institute for Neurosciences Thomas Jefferson University Philadelphia, Pennsylvania.

Sensory integration is one of the most highly utilized interventions in autism, however, a lack of consensus exists regarding its evidence base. An increasing number of studies are investigating the effectiveness of this approach. This study used the Council for Exceptional Children (CEC) Standards for Evidence-based Practices in Special Education to evaluate the effectiveness research from 2006 to 2017 on Ayres Sensory Integration (ASI) intervention for children with autism. Read More

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December 2018
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Dissemination of the CAPABLE Model of Care in a Medicaid Waiver Program to Improve Physical Function.

J Am Geriatr Soc 2018 Dec 13. Epub 2018 Dec 13.

School of Nursing, Johns Hopkins University, Baltimore, Maryland.

Background/objectives: Of older adults, 42% report problems with daily function, and physical function is the most important consideration for aging individuals. Thus, we implemented a model of care focused on improving physical function and examined health and use outcomes and satisfaction.

Design: A 3-year participatory, single-group pretrial/posttrial benchmarked to a usual care cohort that was evaluated prior to the study. Read More

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December 2018

Evidence-based skin care in preterm infants.

Pediatr Dermatol 2018 Dec 12. Epub 2018 Dec 12.

Department of Dermatology, University of California, San Diego School of Medicine, San Diego, California.

Most guidelines on neonatal skin care emphasize issues pertaining to healthy, term infants. Few address the complex task of skin barrier maintenance in preterm, very preterm, and extremely preterm infants. Here, we provide an evidence-based review of the literature on skin care of preterm neonates. Read More

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December 2018
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The effect of a teamwork intervention on staff perception of teamwork and patient care on a medical surgical unit.

Nurs Forum 2018 Dec 12. Epub 2018 Dec 12.

School of Nursing, Western Kentucky University, Bowling Green, Kentucky.

As a result of the ever-changing health care environment and patient complexity, it is difficult for nursing teams to provide safe quality care and complete all tasks, also known as missed nursing care. Missed nursing care is a global health care issue and defined as any aspect of care missed in part, in whole, or delayed. Teamwork has been found to not only positively impact the performance of a team, but also patient outcomes. Read More

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December 2018

Update on the Role of Research in the Oncology Nursing Society.

Oncol Nurs Forum 2019 Jan;46(1):11-14

Oncology Nursing Society.

Changes are underway at the Oncology Nursing Society to align resources so that scientists have the support needed to generate new knowledge and clinicians have access to tools needed to use evidence-based interventions that can speed the translation of research to transform cancer care. Read More

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January 2019

Epidemiological association between multiple chemical sensitivity and birth by caesarean section: a nationwide case-control study.

Environ Health 2018 Dec 14;17(1):89. Epub 2018 Dec 14.

Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, 18-1 Sakuradai, Minami-ku, Sagamihara, Kanagawa, 252-0392, Japan.

Introduction: Multiple chemical sensitivity (MCS) is characterized by recurrent nonspecific symptoms that are attributed to exposure to trace levels of environmental agents. Although the clinical symptoms of MCS have been described in several studies, the risk factors for this condition remain unclear. Our aim was to clarify the risk factors for MCS and the association between MCS and birth by caesarean section. Read More

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December 2018

Using the behavior change wheel to identify barriers to and potential solutions for primary care clinical guideline use in four provinces in South Africa.

BMC Health Serv Res 2018 Dec 14;18(1):965. Epub 2018 Dec 14.

Department of Public Health Sciences, Karolinska Institutet, Tomtebodavägen 18A, 17177, Stockholm, Sweden.

Background: Clinical practice guidelines risk having little impact on healthcare if not effectively implemented. Theory informed, targeted implementation may maximise their impact. Our study explored barriers to and facilitators of guideline implementation and use by South African primary care nurses and allied healthcare workers in four provinces in South Africa. Read More

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December 2018

The development of a survey instrument to measure the barriers to the conduct and application of research in complementary and alternative medicine: a Delphi study.

BMC Complement Altern Med 2018 Dec 14;18(1):335. Epub 2018 Dec 14.

Department of Rural Health, University of South Australia, North Terrace, Adelaide, SA, 5000, Australia.

Background: As Complementary and Alternative medicine (CAM) grows in popularity, there is overt recognition for research evidence to inform clinical practice. While various strategies have been trialed to overcome the barriers to such progress, it is important to first understand the extent to which these barriers impact the conduct and application of CAM research. This study aimed to garner consensus and agreement among CAM researchers and practitioners in refining and validating a preliminary survey instrument for measuring these barriers. Read More

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December 2018

Using PhotoVoice to Understand Health Determinants of Formerly Homeless Individuals Living in Permanent Housing in Detroit.

Qual Health Res 2018 Dec 14:1049732318816670. Epub 2018 Dec 14.

4 Neighborhood Service Organization, Detroit, Michigan, USA.

Housing First is an evidence-based approach to addressing chronic homelessness that provides permanent, low-barrier housing. Previous literature on the health of tenants of Housing First programs has primarily focused on mental health, substance use, and health care. Using the social-ecological model, we conducted a community-based participatory research (CBPR) PhotoVoice study to better understand what Housing First residents in Detroit identify as factors that impact their health. Read More

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December 2018

A case of fulminant myocarditis treated with very long-term support by cardiopulmonary support system.

J Cardiol Cases 2016 Nov 6;14(5):141-144. Epub 2016 Aug 6.

Cardiovascular Center, Munakata Suikokai General Hospital, Fukutsu, Japan.

Fulminant myocarditis (FM) sometimes causes severe left ventricular dysfunction and lethal arrhythmias leading to cardiogenic shock and critical conditions. Thus, mechanical circulation support with intra-aortic balloon pumping and/or a cardiopulmonary support system (CPS) is sometimes needed to save lives. The special recommended therapies for FM for that classified as class I (evidence level C) in the guidelines of the Japanese Circulation Society are intra-aortic balloon pumping, CPS, percutaneous cardiac pacing, and a left ventricular assist device (LVAD), and they are well established in evidence-based medicine. Read More

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November 2016

Group Therapy for Substance Use Disorders: A Survey of Clinician Practices.

J Groups Addict Recover 2017 8;12(4):243-259. Epub 2017 Dec 8.

Department of Psychology, University of Michigan.

Substance use disorder (SUD) treatment is typically delivered in group format, but clinical research focuses on individual therapy. This exploratory study narrows this gap through a survey of 566 SUD group clinicians in the United States, concerning most commonly used group practices, attitudes about evidence-based treatments (EBTs), and beliefs about addiction. Clinicians reported high use of open groups, moderately high utilization of EBT practices, and moderate use of questionable practices. Read More

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December 2017

Pembrolizumab for Locally Advanced or Metastatic Urothelial Cancer Where Cisplatin is Unsuitable: An Evidence Review Group Perspective of a NICE Single Technology Appraisal.

Pharmacoeconomics 2018 Dec 13. Epub 2018 Dec 13.

University College London Hospitals NHS Foundation Trust, London, UK.

As part of its Single Technology Appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer (Merck Sharp & Dohme) of pembrolizumab (Keytruda) to submit evidence of its clinical and cost effectiveness for the treatment of locally advanced or metastatic urothelial cancer where cisplatin is unsuitable. The School of Health and Related Research Technology Appraisal Group at the University of Sheffield was commissioned to act as the independent Evidence Review Group (ERG). The ERG produced a detailed review of the evidence for the clinical and cost effectiveness of the technology, based on the company's submission (CS) to NICE. Read More

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December 2018

Standardized Cost Estimates for Home Visiting: Pilot Study of the Home Visiting Budget Assistance Tool (HV-BAT).

Matern Child Health J 2018 Dec 13. Epub 2018 Dec 13.

Division of Home Visiting and Early Childhood Systems, HRSA, Maternal and Child Health Bureau, 5600 Fishers Lane, Rockville, MD, 20857, USA.

Purpose Using a standardized approach and metrics to estimate home visiting costs across multiple evidence-based models and regions could improve the consistency and accuracy of cost estimates, allow stakeholders to observe trends in cost allocation, analyze how home visiting costs vary, and develop future program budgets. Between October 2015 and December 2018, we developed and pilot-tested the Home Visiting Budget Assistance Tool (HV-BAT) to standardize the collection of home visiting program costs and analyze costs for local implementing agencies (LIAs). Methods We recruited LIAs that implemented at least one of nine evidence-based home visiting models in 15 states implementing the Maternal, Infant, and Early Childhood Home Visiting (MIECHV) Program. Read More

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December 2018

Age as a Moderator of Social Skills Intervention Response Among Korean Adolescents with Autism Spectrum Disorder.

J Autism Dev Disord 2018 Dec 13. Epub 2018 Dec 13.

Department of Psychiatry, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam, Gyeonggi, 13620, South Korea.

Few studies have investigated the effect of age on treatment effectiveness of evidence-based social skills training in autism spectrum disorder (ASD) adolescents. This study evaluated the effectiveness of Program for the Education and Enrichment of Relational Skills (PEERS) in different ages of ASD adolescents. A total of 110 ASD adolescents aged 11-19 years were divided into early, middle, and late adolescence groups, and the changes in outcome measures following intervention were compared among the three groups. Read More

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December 2018

Optimizing medical care for geriatric patients in Austria: defining a top five list of "Choosing Wisely" recommendations using the Delphi technique.

Eur Geriatr Med 2018 27;9(6):783-793. Epub 2018 Sep 27.

14Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria.

Purpose: Inappropriate use of diagnostic and therapeutic medical procedures is common and potentially harmful for older patients. The Austrian Society of Geriatrics and Gerontology defined a consensus of five recommendations to avoid overuse of medical interventions and to improve care of geriatric patients.

Methods: From an initial pool of 147 reliable recommendations, 20 were chosen by a structured selection process for inclusion in a Delphi process to define a list of five top recommendations for geriatric medicine. Read More

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September 2018

Surgical strategy for temporal lobe epilepsy with dual pathology and incomplete evidence from EEG and neuroimaging.

Exp Ther Med 2018 Dec 19;16(6):4886-4892. Epub 2018 Sep 19.

Department of Neurosurgery, The Second Hospital of Dalian Medical University, Dalian, Liaoning 116000, P.R. China.

Coexistence of hippocampal sclerosis (HS) and a temporal neocortical lesion, including focal cortical dysplasia, vascular malformations or benign primary brain tumors, is defined as dual pathology. In the majority of cases, the complete evidence based on electroencephalogram (EEG) and magnetic resonance imaging (MRI) for each of the dual pathological lesions is difficult to obtain. As a result, patients with dual pathology are poor surgical candidates due to potential incomplete resection of the epileptogenic zone. Read More

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December 2018

The Effects of Natural Daylight on Length of Hospital Stay.

Environ Health Insights 2018 3;12:1178630218812817. Epub 2018 Dec 3.

Department of Psychiatry, School of Medicine, Ajou University, Suwon, Korea.

Background And Purpose: While providing medical services, hospitals generate many data about patients. Such medical data could contribute to better treatments once their associations or patterns have been identified. With properly analyzed medical data, traditional knowledge at an individual level could be further extended to broader populations. Read More

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December 2018

Health Dynamics in the Built Environment: An Urban Intensity Perspective - An Exploratory Study in Trinidad and Tobago.

Environ Health Insights 2018 29;12:1178630218811342. Epub 2018 Nov 29.

Centre for Environmental Studies and Applied Life Sciences, The University of Trinidad and Tobago, Arima, Trinidad and Tobago.

The built environment encompasses the physical components of the environment, inclusive of infrastructure, households, buildings, streets, and open spaces, within which individuals reside and carry out their daily activities. It affects both indirectly and directly on the outdoor and indoor physical environment as well as the socio-economic environment. The elements which comprise the built environment and those of the physical and socio-economic environments, which are affected by it, are recognised as key determinants of health. Read More

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November 2018

Evidence based or evidence biased!

Authors:
Indu Bhusan Kar

Natl J Maxillofac Surg 2018 Jul-Dec;9(2):115-116

Department of Oral and Maxillofacial Surgery, SCB Dental College and Hospital, Cuttack, Odisha, India. E-mail:

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December 2018

Low back pain.

Nat Rev Dis Primers 2018 Dec 13;4(1):52. Epub 2018 Dec 13.

Center for Health and Medical Psychology, School of Law, Psychology, and Social Work, Örebro University, Örebro, Sweden.

Low back pain affects individuals of all ages and is a leading contributor to disease burden worldwide. Despite advancements in assessment and treatment methods, the management of low back pain remains a challenge for researchers and clinicians alike. One reason for the limited success in identifying effective treatments is the large variation in the manifestations, possible causes, precipitating and maintaining factors, course, prognosis and consequences in terms of activity interference and quality of life. Read More

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December 2018

Variation in Integrated Head and Neck Cancer Care: Impact of Patient and Hospital Characteristics.

J Natl Compr Canc Netw 2018 Dec;16(12):1491-1498

Scientific Center for Quality of Healthcare, and Department of Otolaryngology, Head and Neck Surgery, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen; Department of Otorhinolaryngology, Head and Neck Surgery, Erasmus MC Cancer Institute, Rotterdam; Department of Medical Oncology, Antoni van Leeuwenhoek Nederlands Kanker Instituut, Amsterdam; Department of Oral and Maxillofacial Surgery, Rijnstate Hospital, Arnhem; Department of Oral and Maxillofacial Surgery, Noordwest Ziekenhuisgroep, Alkmaar; Department of Oral and Maxillofacial Surgery, Maastricht University Medical Center, Maastricht; Department of Research, Netherlands Comprehensive Cancer Organisation, Utrecht; Department of Epidemiology, University of Groningen, University Medical Centre Groningen, Groningen; Department of Head and Neck Surgical Oncology, UMC Utrecht Cancer Centre, Utrecht; Department of Radiation Oncology (MAASTRO), GROW - School for Oncology and Developmental Biology, Maastricht University Medical Centre, Maastricht; Department of Oral and Maxillofacial Surgery, Medisch Spectrum Twente, Enschede; Department of Otolaryngology, Head and Neck Surgery, Elisabeth Tweesteden Ziekenhuis Tilburg, Tilburg; Department of Otorhinolaryngology, Head and Neck Surgery, Leiden University Medical Centre, Leiden; Department of Otolaryngology, Head and Neck Surgery, MC Haaglanden-Bronovo, The Hague; Department of Oral and Maxillofacial Surgery, Medical Centre Leeuwarden, Leeuwarden; Department of Otolaryngology, Head and Neck Surgery, VU University Medical Centre, Amsterdam; Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Centre Groningen, Groningen; Department of Head and Neck Surgery and Oncology, Antoni van Leeuwenhoek Nederlands Kanker Instituut, Amsterdam; Department of Oral and Maxillofacial Surgery, Academisch Medisch Centrum, Amsterdam Zuid-Oost; and Department of Oral and Maxillofacial Surgery, Radboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen, the Netherlands.

Monitoring and effectively improving oncologic integrated care requires dashboard information based on quality registrations. The dashboard includes evidence-based quality indicators (QIs) that measure quality of care. This study aimed to assess the quality of current integrated head and neck cancer care with QIs, the variation between Dutch hospitals, and the influence of patient and hospital characteristics. Read More

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December 2018
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New Cancer Drug Approvals From the Perspective of a Universal Healthcare System: Analyses of the Pan-Canadian Oncology Drug Review Recommendations.

J Natl Compr Canc Netw 2018 Dec;16(12):1460-1466

CancerCare Manitoba, and University of Manitoba, Winnipeg, Manitoba, Canada.

FDA approvals do not consider cost, but they set the tone for regulatory approvals worldwide, including in countries with universal healthcare where cost-effectiveness, utility, and adoption feasibility are considered rigorously. Data from the pan-Canadian Oncology Drug Review (pCODR), a national drug review system that makes evidence-based funding recommendations to Canada's provinces and territories, were collected. Our objectives were to assess (1) temporal trends in cost and efficacy of drugs reviewed, (2) correlations among magnitude of benefits, cost, and pCODR decisions, and (3) predictors of approvals. Read More

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December 2018

Strengthening national vaccine decision-making: Assessing the impact of SIVAC Initiative support on national immunisation technical advisory group (NITAG) functionality in 77 low and middle-income countries.

Vaccine 2018 Dec 10. Epub 2018 Dec 10.

Department of Infectious Disease Epidemiology, Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, Keppel Street, WC1E 7HT London, United Kingdom; Modelling and Economics Unit, Public Health England, 61 Colindale Avenue, NW9 5EQ London, United Kingdom. Electronic address:

Background: National Immunisation Technical Advisory Groups (NITAGs) are multi-disciplinary expert groups that provide policy-makers with independent, evidence-based advice on vaccination. Between 2008 and 2017, the SIVAC Initiative supported establishment and strengthening of NITAGs in low and lower-middle income countries though its impact was never assessed quantitatively.

Aim: To quantitatively assess whether SIVAC support is associated with a faster rate at which NITAGs became functional based on six performance indicators. Read More

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December 2018

A randomized controlled trial assessing the efficacy of a self-administered psycho-educational intervention for patients with cancer.

Patient Educ Couns 2018 Dec 3. Epub 2018 Dec 3.

Louise Granofsky Psychosocial Oncology Program, Segal Cancer Center, Jewish General Hospital, Montreal, Canada; Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Canada; Departments of Psychology, Oncology and Psychiatry, McGill University, Montreal, Canada.

Objective: Bibliotherapy refers to psychological self-help interventions that utilize treatment books to improve psychological well-being. Research supports bibliotherapy as an efficacious intervention for a variety of mental health problems. Yet, few studies have investigated bibliotherapy in psychosocial oncology. Read More

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December 2018

Building a culture of safety in interventional radiology.

Tech Vasc Interv Radiol 2018 Dec 29;21(4):198-204. Epub 2018 Jul 29.

Program Director Vascular Interventional Radiology, University of North Carolina at Chapel Hill, Campus Box 7510, Chapel Hill, NC. Electronic address:

Safety in medicine is a pressing issue. It has been shown that deaths due to medical error range from 98,000 to 400,000 per year in the United States. Since this issue was broached in 1999, a variety of clinical and institutional safety interventions have been pioneered; however, the medical community has realized that without a strong institutional safety culture, the efficacy of these interventions is limited. Read More

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December 2018

Annual review of selected scientific literature: A report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry.

J Prosthet Dent 2018 Dec;120(6):816-878

Private practice oral and maxillofacial surgery, Ansbach, Bavaria, Germany.

Problem: There are countless numbers of scientific studies published in countless scientific journals on subjects related to restorative dentistry.

Purpose: The purpose of this article is to review pertinent scientific studies published in 2017 on topics of interest to restorative dentists.

Methods And Materials: The authors, considered to be experts in their disciplines searched the scientific literature in 7 different areas (prosthodontics, periodontics, dental materials, occlusion and temporomandibular disorders, sleep-disordered breathing, oral medicine and oral and maxillofacial surgery and dental caries). Read More

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December 2018

The changing landscape of phase II/III metastatic sarcoma clinical trials-analysis of ClinicalTrials.gov.

BMC Cancer 2018 Dec 13;18(1):1251. Epub 2018 Dec 13.

Department of Medical Melanoma and Sarcoma, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, 651 East Dongfeng Road, Guangzhou, 510060, China.

Background: Well-designed clinical trials are of great importance in validating novel treatments and ensuring an evidence-based approach for sarcoma. This study aimed to provide a comprehensive landscape of the characteristics of metastatic or advanced sarcoma clinical trials using the substantial resource of the ClincialTrials.gov database. Read More

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December 2018

Knowledge, perceptions, and clinical experiences on molar incisor hypomineralization among dental care providers in Hong Kong.

BMC Oral Health 2018 Dec 13;18(1):217. Epub 2018 Dec 13.

Paediatric Dentistry, Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong, SAR, China.

Background: Molar incisor hypomineralization (MIH) is an alarming problem with considerable challenges in management. This study aimed to evaluate and compare the knowledge, perceptions, and clinical experiences of molar incisor hypomineralization (MIH) between general dental practitioners (GDPs) and paediatric dentists (PDs) in Hong Kong.

Methods: A cross-sectional survey of 557 randomly selected GDPs (approximately 25% of all registered dentists) and all registered PDs (n = 31) were invited. Read More

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December 2018

Examining trends in inequality in the use of reproductive health care services in Ghana and Nigeria.

BMC Pregnancy Childbirth 2018 Dec 13;18(1):492. Epub 2018 Dec 13.

Department of Health Services Research, CAPHRI, Maastricht University Medical Center, Faculty of Health, Medicine and Life Sciences, Maastricht University, PO Box 616, 6200MD, Maastricht, The Netherlands.

Background: Equitable use of reproductive health care services is of critical importance since it may affect women's and children's health. Policies to reduce inequality in access to reproductive health care services are often general and frequently benefit the richer population. This is known as the inverse equity situation. Read More

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December 2018

Irish general practitioners' view of perinatal mental health in general practice: a qualitative study.

BMC Fam Pract 2018 Dec 13;19(1):196. Epub 2018 Dec 13.

School of Allied Health, Faculty of Education & Health Sciences, Health Sciences Building, University of Limerick, Limerick, Ireland.

Background: Identification of perinatal mental health problems and effective care for women who experience them are important considering the potentially serious impact that they may have on the wellbeing of the woman, her baby, family and wider society. General practitioners (GPs) play a central role in identifying and supporting women and this study aimed to explore GPs' experiences of caring for women with perinatal mental health problems in primary care. The results of this study may provide guidance to inform policy, practice, research and development of curriculum and continuous professional development resources. Read More

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December 2018

[Irritable bowel syndrome: comorbid psychiatric disorders and psychological treatment options].

Orv Hetil 2018 Dec;159(50):2115-2121

Pszichológiai Intézet, Eötvös Loránd Tudományegyetem Budapest, Izabella u. 46., 1064.

Irritable bowel syndrome is a chronic functional gastrointestinal disorder with a prevalence of 7-21%. It has a negative impact on health-related quality of life and work productivity and it is associated with increased psychological distress and mental comorbidity, like major depression disorder and generalised anxiety disorder. Due to biopsychosocial factors and the brain-gut axis playing a key role in the aetiology of the disease, the use of psychological treatments has great importance in the therapy of irritable bowel syndrome. Read More

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December 2018