158,044 results match your criteria Evidence-Based Ophthalmology[Journal]


Periconceptional intake of folic acid among low-risk women in Canada: summary of a workshop aiming to align prenatal folic acid supplement composition with current expert guidelines.

Am J Clin Nutr 2018 Dec;108(6):1357-1368

School of Nutrition Sciences, University of Ottawa, Ottawa, Ontario, Canada.

The Government of Canada and the Society of Obstetricians and Gynaecologists of Canada both recommend a daily multivitamin supplement containing 400 µg folic acid (FA) for the primary prevention of neural tube defects among low-risk women from before conception and throughout lactation. Prenatal supplements marketed and prescribed in Canada typically exceed the recommended dose, usually providing ≥1000 µg FA/d. This high daily dose, coupled with staple-food FA fortification, has resulted in the observation of very high blood folate concentrations among reproductive-aged women consuming FA-containing supplements. Read More

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December 2018

Factors Predicting Adoption of the Nurses Improving Care of Healthsystem Elders Program.

Nurs Res 2019 Jan/Feb;68(1):13-21

Amy Witkoski Stimpfel, PhD, RN, is Assistant Professor, Rory Meyers College of Nursing, New York University, New York. Mattia J. Gilmartin, PhD, RN, FAAN, is Executive Director, NICHE, Rory Meyers College of Nursing, New York University, New York. At the time the research was completed, Dr. Gilmartin was a Senior Research Scientist at Rory Meyers College of Nursing, New York University.

Background: Registered nurses are often underprepared with the knowledge and skills to care for hospitalized older adult patients. One strategy to bridge this gap is for hospitals to adopt the Nurses Improving Care for Healthsystem Elders (NICHE) program: A nurse-led interdisciplinary organizational intervention to improve care of hospitalized older adults.

Objectives: This study aimed to identify the market, organizational and managerial, and sociotechnical factors associated with the adoption of NICHE among U. Read More

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December 2018
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The Titration and Tolerability of Sacubitril/Valsartan for Patients with Heart Failure in Clinical Practice.

J Cardiovasc Pharmacol 2018 Dec 10. Epub 2018 Dec 10.

University of Alberta, Edmonton, Canada.

Little is known about the dosing and tolerability of sacubitril/valsartan (LCZ696; Entresto™, Quebec, Canada) in a non-clinical trial population. This study was conducted to evaluate the use and tolerability of sacubitril/valsartan in patients followed at a multidisciplinary heart failure clinic. We performed a retrospective chart review of 126 patients with heart failure, initiated on sacubitril/valsartan, and seen at a specialty heart failure clinic between August 1, 2015 and August 1, 2017. Read More

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December 2018

Assessment and management of coronary artery disease in kidney and pancreas transplant candidates.

J Cardiovasc Med (Hagerstown) 2018 Dec 11. Epub 2018 Dec 11.

Department of Medicine, Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

: Patients with end-stage renal disease (ESRD) undergoing evaluation for kidney and/or pancreas transplantation represent a population with unique cardiovascular (CV) profiles and unique therapeutic needs. Coronary artery disease (CAD) is common in patients with ESRD, mediated by both the overrepresentation and higher prognostic value of traditional CV risk factors amongst this population, as well as altered cardiovascular responses to failing renal function, likely mediated by dysregulation of the renin-angiotensin-aldosterone system (RAAS) and abnormal calcium and phosphate metabolism. Within the ESRD population, obstructive CAD correlates highly with adverse coronary events, including during the peri-transplant period, and successful revascularization may attenuate some of that increased risk. Read More

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December 2018

An integrative review of nurse practitioner education models: Part three of a four-part series on critical topics identified by the 2015 Nurse Practitioner Research Agenda.

J Am Assoc Nurse Pract 2018 Dec;30(12):696-709

Rush University College of Nursing, Chicago, Illinois.

Background And Purpose: Critical research topics were identified after nurse practitioner (NP) organization stakeholders participated in the Fellows of the American Association of Nurse Practitioner, 2015 Nurse Practitioner Research Agenda Roundtable. Strategies and recommendations were identified to support further work examining NP outcomes-based research priorities in four areas: 1) policy and regulation; 2) workforce; 3) education; and 4) practice. For the purpose of this article, we focus on NP education. Read More

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December 2018

Development and Usability Testing of the Society for Pediatric Anesthesia Pedi Crisis Mobile Application.

Anesth Analg 2018 Dec 11. Epub 2018 Dec 11.

United States National Aeronautics and Space Administration, Ames Research Center, Moffett Field, California.

When life-threatening, critical events occur in the operating room, the fast-paced, high-distraction atmosphere often leaves little time to think or deliberate about management options. Success depends on applying a team approach to quickly implement well-rehearsed, systematic, evidence-based assessment and treatment protocols. Mobile devices offer resources for readily accessible, easily updatable information that can be invaluable during perioperative critical events. Read More

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December 2018

Exploring the Role of Regional Anesthesia in the Treatment of the Burn Injured Patient: A Narrative Review of Current Literature.

Clin J Pain 2018 Dec 11. Epub 2018 Dec 11.

The University of Queensland, School of Nursing, Midwifery and Social Work, St Lucia, QLD, Australia, 4072.

Objectives: The review article was designed to assess the effectiveness of regional anesthesia, specifically peripheral nerve blocks, in the treatment of burn pain; with noting of clinical indications and contraindications for peripheral nerve block application, along with discussion of evidence-based analgesic strategies for providing improved, comprehensive burn pain management.

Methods: A search of relevant literature was performed using CINAHL, PubMed, EMBASE, Web of Science and SCOPUS with a publication date between January 2005 and December 2017.

Results: The search yielded ten results that met criteria. Read More

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December 2018

Value-based medicine in oncology: the importance of perspective in the emerging value frameworks.

Clinics (Sao Paulo) 2018 Dec 10;73(suppl 1):e470s. Epub 2018 Dec 10.

Centro de Investigacao Translacional em Oncologia, Instituto do Cancer do Estado de Sao Paulo (ICESP), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.

Recently, professional and healthcare-related entities have launched frameworks designed to assess the value of cancer innovations in multistakeholder decision processes. Among the most visible entities that propose and implement value frameworks in oncology are the European Society of Medical Oncology (ESMO), the American Society of Clinical Oncology (ASCO), the Memorial Sloan Kettering Cancer Center (MSKCC) and the National Comprehensive Cancer Network (NCCN). However, these value frameworks have been criticized for conceptual inconsistencies, inability to include a greater variety of value criteria, and inadequate explanation of the uncertainty approach used in the modeling process. Read More

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December 2018

Brazilian guidelines for the management of psychomotor agitation. Part 1. Non-pharmacological approach.

Braz J Psychiatr 2018 Dec 6. Epub 2018 Dec 6.

Comissão de Emergências Psiquiátricas, Associação Brasileira de Psiquiatria (ABP), Rio de Janeiro, RJ, Brazil.

Objective: To present the essential guidelines for non-pharmacological management of patients with psychomotor agitation in Brazil.

Methods: These guidelines were developed based on a systematic review of articles published from 1997 to 2017, retrieved from MEDLINE (PubMed), Cochrane Database of Systematic Review, and SciELO. Other relevant articles identified by searching the reference lists of included studies were also used to develop these guidelines. Read More

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December 2018

[The Münsteraner Memorandum on Alternative Practitioners - Analysis and evaluation of critical commentaries].

Z Evid Fortbild Qual Gesundhwes 2018 Nov 26;137-138:27-35. Epub 2018 Oct 26.

Institut für Ethik, Geschichte und Theorie der Medizin der Universität Münster, Deutschland. Electronic address:

With its "Münsteraner Memorandum on Alternative Practitioners" the author collective "Münsteraner Kreis" has recently criticized current German double standards for physicians versus alternative practitioners with regard to minimal competency and to quality assurance. The authors' main goal was to attract attention to the problem and to provide systematic arguments in favor of a healthcare system that is serving patients' needs more appropriately. Reactions to the Memorandum were numerous, divergent in their evaluations, often constructive, and frequently emotionally heated. Read More

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November 2018

Effect of the Diverse Standardized Patient Simulation (DSPS) Cultural Competence Education Strategy on Nursing Students' Transcultural Self-Efficacy Perceptions.

Authors:
Eda Ozkara San

J Transcult Nurs 2018 Dec 12:1043659618817599. Epub 2018 Dec 12.

1 Pace University, New York, NY, USA.

Introduction: Standardized patient simulation can be an effective strategy to foster culturally competence education.

Methodology: Guided by the cultural competence and confidence model, this grant-funded, longitudinal, one-group, pretest and posttest study used the Transcultural Self-Efficacy Tool (TSET) to examine the effect of the Diverse Standardized Patient Simulation (DSPS) cultural competence education strategy on students' ( n = 53) transcultural self-efficacy. Developed by following recommended guidelines and standards, the DSPS had content validity review. Read More

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December 2018

Three Out of Ten Working Patients Expect No Clinical Improvement of Their Ability to Perform Work-Related Knee-Demanding Activities After Total Knee Arthroplasty: A Multicenter Study.

J Occup Rehabil 2018 Dec 11. Epub 2018 Dec 11.

Department Coronel Institute of Occupational Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.

Purpose Three out of ten patients do not return to work after total knee arthroplasty (TKA). Patient expectations are suggested to play a key role. What are patients' expectations regarding the ability to perform work-related knee-demanding activities 6 months after TKA compared to their preoperative status? Methods A multi-center cross-sectional study was performed among 292 working patients listed for TKA. Read More

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December 2018

Autism Spectrum Disorder and the Experience of Traumatic Events: Review of the Current Literature to Inform Modifications to a Treatment Model for Children with Autism.

J Autism Dev Disord 2018 Dec 11. Epub 2018 Dec 11.

Department of Educational and Counselling Psychology, Faculty of Education, University of British Columbia, 2125 Main Mall, Vancouver, BC, V6T 1Z4, Canada.

Children with autism incur trauma and have increased vulnerabilities for experiencing trauma. This paper summarizes the current literature in the study of trauma in typically developing children and those with autism. A treatment model for children with autism, drawing on components from cognitive behavior therapy (CBT), trauma-focused CBT, and CBT to teach emotion regulation and treat anxiety in children with autism is suggested. Read More

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December 2018

Re: Brazilian Consensus Recommendation on the Use of Polymethylmethacrylate Filler in Facial and Corporal Aesthetics by Túlio Armanini Blanco Souza, Letícia Marques Colomé, Eduardo André Bender, Gottfriede Lemperle Aesthethic Plastic Surgery 2018; 42(5): 1244-51.

Aesthetic Plast Surg 2018 Dec 11. Epub 2018 Dec 11.

Brazilian Society of Plastic Surgery (Sociedade Brasileira de Cirurgia Plástica), Rua Funchal, 129, 2 andar - Vila Olímpia, São Paulo, SP, CEP 04551-060, Brazil.

The self-titled study Brazilian Consensus Recommendation cannot be considered a consensus and more specifically cannot be considered a Brazilian consensus. The study does not represent the point-of-view of members of the Brazilian Society of Plastic Surgery. The content of this paper is plenty of contradictory and questionable affirmations. Read More

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December 2018

Social Thinking®, Pseudoscientific, Not Empirically Supported, and Non-Evidence Based: a Reply to Crooke and Winner.

Behav Anal Pract 2018 Dec 8;11(4):456-466. Epub 2018 Mar 8.

Autism Partnership Foundation, 200 Marina Drive, Seal Beach, CA 90740 USA.

J. B. Leaf et al. Read More

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December 2018

Evidence-Based Practice in Primary Care Occupational Therapy: A Cross-Sectional Survey in Sweden.

Occup Ther Int 2018 28;2018:5376764. Epub 2018 Oct 28.

Närhälsan Research and Development Primary Health Care, Region Västra Götaland, Gothenburg, Sweden.

Introduction: Understanding of attitudes, knowledge, and behaviour related to evidence-based practice (EBP) and guidelines in Swedish occupational therapy is limited. The study aims were to investigate attitudes, knowledge, and behaviour related to evidence-based practice and guidelines of Swedish occupational therapists in primary care.

Methods: A web-based survey of 94 Swedish primary care occupational therapists (response rate 53. Read More

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October 2018

Highlights of the Updated Evidence-Based IBS Treatment Monograph.

Gastroenterol Hepatol (N Y) 2018 Nov;14(11):665-667

David M. Underwood Chair of Medicine in Digestive Disorders Houston Methodist Hospital Professor of Medicine Weill Cornell Medical College Houston, Texas.

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November 2018

Approach of minimal invasive monitoring and initial treatment of the septic patient in emergency medicine.

Open Access Emerg Med 2018 20;10:183-191. Epub 2018 Nov 20.

Emergency Medicine, Universidad del Rosario, Bogotá, Colombia.

Sepsis and septic shock constitute a complex disease condition that requires the engagement of several medical specialties. A great number of patients with this disease are constantly admitted to the emergency department, which warrants the need for emergency physicians to lead in the recognition and early management of septic patients. Timely and appropriate interventions may help reduce mortality in a disease with an unacceptably high mortality rate. Read More

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November 2018

Comparative effectiveness of different chemotherapy regimens of advanced-stage Hodgkin lymphoma in adults: a network meta-analysis.

Cancer Manag Res 2018 22;10:6017-6028. Epub 2018 Nov 22.

Department of Oncology, Weifang Traditional Chinese Hospital, Weifang, Shandong Province, People's Republic of China,

Background: Combined chemotherapy is the cornerstone treatment for patients with advanced Hodgkin lymphoma (HL). The objective of our study was to perform a network meta-analysis of the efficacy of different chemotherapy regimens in adults with advanced-stage HL.

Materials And Methods: We searched for relevant randomized controlled trials (RCTs) in titles/abstracts in PubMed, Embase, and the Cochrane Library. Read More

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November 2018

Dysfunctional phagocytosis capacity, granulocyte recruitment and inflammatory factor secretion of Kupffer cells in diabetes mellitus reversed by Lidocaine.

Diabetes Metab Syndr Obes 2018 26;11:827-834. Epub 2018 Nov 26.

Department of Gynaecology and Obstetrics, Beijing Key Laboratory of Cancer Therapeutic Vaccine, Beijing 100038, China,

Purpose: Kupffer cells (KCs) present dysfunctional immunity capacity among the diabetes mellitus patients. This study aims to investigate whether Lidocaine could reverse dysfunctions of KCs, in terms of phagocytosis, granulocyte recruitment and inflammatory mediator secretion.

Methods: db/db and C57BL/6 mice were employed to establish diabetic and nondiabetic models. Read More

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November 2018

Clinical efficacy of immune checkpoint inhibitors in the treatment of unresectable advanced or recurrent gastric cancer: an evidence-based review of therapies.

Onco Targets Ther 2018 21;11:8239-8250. Epub 2018 Nov 21.

Department of Internal Medicine, Division of Gastroenterology and Hepatology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan,

Standard treatment options for patients with advanced gastric cancer (GC) offer limited efficacy and are associated with some toxicity, which necessitates the development of more effective therapies for improving the treatment outcomes for this disease. Immunotherapy involving immune checkpoint inhibitors (ICIs) which inhibit the programmed death 1 (PD-1)/programmed death ligand 1 interaction has emerged as a new treatment option. Nivolumab, a human IgG4 monoclonal antibody inhibitor of PD-1, has demonstrated promising clinical activity and induced durable responses in patients with advanced GC. Read More

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November 2018
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New therapeutic strategies in systemic lupus erythematosus management.

Nat Rev Rheumatol 2018 Dec 11. Epub 2018 Dec 11.

Unit of Rheumatology, Department of Medicine, University of Padova, Padova, Italy.

The current treatment approach for systemic lupus erythematosus (SLE), as outlined in the recommendations by international medical associations including EULAR and the ACR, is mostly eminence-based rather than evidence-based. However, knowledge on SLE is growing quickly, and such new advances need to be translated into clinical practice. Questions remain regarding the choice and timing of drug administration and tapering until withdrawal, which both can affect the balance between the control of disease activity and damage to organs triggered by long-standing and/or disproportionate immunosuppression. Read More

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December 2018

A cross-sectional study to assess Evidence-Based Medicine teaching method: online or face-to-face?

BMJ Evid Based Med 2018 Dec 11. Epub 2018 Dec 11.

Department of Critical Care Medicine, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

We aimed to study differences in postgraduate students' achievement if they are taught evidence-based medicine (EBM) by face-to-face or by online learning. We assessed the performance of 28 postgraduate students who completed a face-to-face learning module and 34 students who completed an online learning module in a cross-sectional study. The teaching materials were the same in both courses so that any performance difference would be due to the teaching method. Read More

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December 2018

Predicting a 'difficult cholecystectomy' after mild gallstone pancreatitis.

HPB (Oxford) 2018 Dec 8. Epub 2018 Dec 8.

Department of Surgery, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, Netherlands. Electronic address:

Background: Cholecystectomy after gallstone pancreatitis may be technically demanding. The aim of this study was to investigate risk factors for a difficult cholecystectomy after mild pancreatitis.

Methods: This was a prospective study within a randomized controlled trial on the timing of cholecystectomy after mild gallstone pancreatitis. Read More

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December 2018

A manual-based intervention for carers of people with dementia and sleep disturbances: an acceptability and feasibility RCT.

Health Technol Assess 2018 Dec;22(71):1-408

Division of Psychiatry, Faculty of Brain Sciences, University College London, London, UK.

Background: It has been estimated that between 25% and 40% of people living with dementia suffer from sleep disturbances, and there are currently no known effective treatments. Sleep disturbances may be the direct result of dementia or due to other comorbidities, such as pain and limited mobility. If carers' sleep is also disturbed, carers too can become tired and stressed, and this sometimes results in the breakdown of care in the home. Read More

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December 2018

Angioplasty and stenting for below the knee ulcers in diabetic patients: protocol for a systematic review.

Syst Rev 2018 Dec 11;7(1):228. Epub 2018 Dec 11.

Division of Vascular and Endovascular Surgery, Department of Surgery, Escola Paulista de Medicina, Universidade Federal de São Paulo, Rua Borges Lagoa 754, São Paulo, 04038-001, SP, Brazil.

Background: The worldwide incidence and prevalence of diabetes mellitus (DM) are increasing. DM has a high social and economic burden due to its complications and associated disorders. Peripheral arterial disease (PAD) is closely related to DM. Read More

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December 2018

The impact of a social norms approach on reducing levels of misperceptions around smokefree hospital entrances amongst patients, staff, and visitors of a NHS hospital: a repeated cross-sectional survey study.

BMC Public Health 2018 Dec 11;18(1):1365. Epub 2018 Dec 11.

Leeds Institute of Health Sciences, School of Medicine, University of Leeds, Leeds, UK.

Background: Smoking is a cause of avoidable morbidity and mortality. In the United Kingdom (UK) the national smoking ban inside hospital buildings is widely adhered to. There is a perception it has led to smokers congregating around hospital entrances (Selbie D. Read More

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December 2018

A Randomized Controlled Trial of Animal-Assisted Therapy as an Adjunct to Intensive Family Preservation Services.

Child Maltreat 2018 Dec 11:1077559518817678. Epub 2018 Dec 11.

1 Graduate School of Social Work, University of Denver, Denver, CO, USA.

Method:: Families referred by Child Protective Services ( M = 6 years ± 4; M = 32 years ± 8.26) were individually randomized to experimental ( n = 14) or control ( n = 14) intervention. Family functioning outcomes were measured using the North Carolina Family Assessment Scale for Reunification. Read More

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December 2018

The neurophysiological and neurochemical effects of alcohol on the brain are inconsistent with current evidence based models of sleepwalking.

Authors:
Mark R Pressman

Sleep Med Rev 2018 Nov 10;43:92-95. Epub 2018 Nov 10.

Sleep Medicine Services, Lankenau Medical Center, Wynnewood, PA, USA; Lankenau Institute for Medical Research, Wynnewood, PA, USA; Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA; Charles Widger School of Law, Villanova University, Villanova, PA, USA. Electronic address:

The DSM-5 and ICSD-3 have removed alcohol from the list of potential triggers for sleepwalking due to the lack of empirical evidence. Recent imaging and EEG based studies of sleepwalking and confusional arousals have provided a more data-based method of examining if alcohol is compatible with what is known about the neurophysiology and neurochemistry of sleepwalking. These studies have demonstrated a deactivation of the frontal areas of the brain, while the cingulate or motor cortex remains active and characterized activation in the form of beta EEG. Read More

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November 2018
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Measuring Value in Post-Acute Care.

Arch Phys Med Rehabil 2018 Dec 8. Epub 2018 Dec 8.

John F. Butzer Center for Research and Innovation, Mary Free Bed Rehabilitation Hospital, Grand Rapids, MI; Division of Rehabilitation, Michigan State University College of Human Medicine, Grand Rapids, MI.

The value of post-acute care is unclear. While experienced clinicians understand the appropriateness of each specific site of post-acute care, clear evidence-based guidelines are not available, and many referrals to post-acute care today are made based on bed availability rather than patient need. Measuring value (value = outcomes / cost) for the entire episode of care has been proposed as an effective method to both evaluate and enable faster innovation in care. Read More

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December 2018

Comparison of Quality Oncology Practice Initiative Metrics in Solid Tumor Oncology Clinic With or Without Concomitant Supportive Oncology Consultation.

J Oncol Pract 2018 Dec;14(12):e786-e793

Icahn School of Medicine at Mount Sinai, New York, NY; and The Everett Clinic, Providence Regional Medical Center, Everett, WA.

Purpose:: The Quality Oncology Practice Initiative (QOPI) is a quality measurement and improvement program designed to assess practice performance for various consensus-based and evidence-based measures. In this study, we evaluated differences in QOPI metrics met among patients with advanced solid cancer receiving routine oncologic care alone (routine care) compared with patients receiving integrated oncology and specialty-level palliative care (supportive care).

Methods:: We conducted a retrospective chart review of 100 randomly selected patients treated between June 2013 and June 2015 from our supportive care group and matched these patients to 100 routine care group patients on the basis of tumor type and initial oncology visit date. Read More

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December 2018

Coming ready or not! An integrative review examining new graduate nurses' transition in acute care.

Int J Nurs Pract 2018 Dec 9:e12714. Epub 2018 Dec 9.

Department of Rural Health, University of Newcastle, Taree, Australia.

Aims: To synthesize the scientific evidence about new graduate nurses' transition to practice in the acute care setting and consider implications for nurses and nursing practice.

Background: Despite the vast amount of literature on new graduate nurses' transition to practice, the transition of new graduate nurses is a global issue and remains at the forefront of discussions within the nursing community.

Design: An integrative review. Read More

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December 2018

Erythrocyte sedimentation rate as an independent prognostic marker for mortality: a prospective population-based cohort study.

J Intern Med 2018 Dec 9. Epub 2018 Dec 9.

Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

Background: A very high erythrocyte sedimentation rate (ESR) is usually an indication of underlying pathology. Additionally, a moderately elevated ESR may also be attributable to biological ageing. Whether the ESR is a prognostic factor for mortality, regardless of age, has been scarcely investigated. Read More

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December 2018

Acute cellular rejection treatment outcomes stratified by Banff grade in pediatric kidney transplant.

Pediatr Transplant 2018 Dec 7:e13334. Epub 2018 Dec 7.

Pediatric Nephrology at Children's Healthcare of Atlanta, Atlanta, Georgia.

Introduction: There are limited data to guide optimal treatment strategies for acute cellular rejection (ACR) based on Banff grade for pediatric kidney transplant recipients. This report reviews a large pediatric transplant center's experience with ACR.

Materials And Methods: A retrospective analysis of pediatric kidney transplant recipients at our center from 2007 to 2014 was performed. Read More

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December 2018

Science for Policy: A Case Study of Scientific Polarization, Values, and the Framing of Risk and Uncertainty.

Risk Anal 2018 Dec 10. Epub 2018 Dec 10.

The Institute for Resources, Environment and Sustainability (IRES), University of British Columbia, Vancouver, British Columbia, Canada.

It is well documented that more research can lead to hardened positions, particularly when dealing with complex, controversial, and value-laden issues. This study is an attempt to unveil underlying values in a contemporary debate, where both sides use scientific evidence to support their argument. We analyze the problem framing, vocabulary, interpretation of evidence, and policy recommendations, with particular attention to the framing of nature and technology. Read More

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December 2018

How often are bath emollients prescribed to children with atopic eczema in primary care in England? A cross-sectional study.

Br J Dermatol 2018 Dec 10. Epub 2018 Dec 10.

Centre of Evidence Based Dermatology, University of Nottingham, King's Meadow Campus, Lenton Lane, Nottingham, NG7 2NR.

Atopic eczema is one of the most burdensome skin diseases across the globe and affects up to 20% of children in the UK. The mainstay of treatment is regular use of emollients including leave-on emollients, soap substitutes and emollient bath additives. However, the lack of evidence to support the use of bath additives has led some to question their role in atopic eczema management. Read More

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December 2018
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Pharmacotherapy in Older Adults with Cardiovascular Disease: Report from an American College of Cardiology, American Geriatrics Society, and National Institute on Aging Workshop.

J Am Geriatr Soc 2018 Dec 7. Epub 2018 Dec 7.

Cardiovascular Division, Department of Internal Medicine, Washington University, St. Louis, Missouri.

Objectives: To identify the top priority areas for research to optimize pharmacotherapy in older adults with cardiovascular disease (CVD).

Design: Consensus meeting.

Setting: Multidisciplinary workshop supported by the National Institute on Aging, the American College of Cardiology, and the American Geriatrics Society, February 6-7, 2017. Read More

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December 2018

Now More Than Ever: The Importance of Reporting Evidence-Based Science.

Authors:
Jan A Nolta

Stem Cells 2018 Dec 11. Epub 2018 Dec 11.

University of California Davis Health System, Stem Cell Program, Sacramento, California, USA.

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December 2018

Does a bounding exercise program prevent hamstring injuries in adult male soccer players? - A cluster -RCT.

Scand J Med Sci Sports 2018 Dec 9. Epub 2018 Dec 9.

Utrecht University, University Medical Center Utrecht, Rudolf Magnus Institute of Neurosciences, Department Rehabilitation, Physical Therapy Science & Sports, Utrecht, The Netherlands.

Background: Although the Nordic Hamstring Exercise (NHE) prevents hamstring injury in soccer players effectively, the annual incidence of these injuries still increases. This may be because of poor long-term compliance with the program. Furthermore, the timing and amplitude of gluteal and core muscle activation seem to play an important role in hamstring injury prevention, the NHE program was not designed to improve activation of these muscles. Read More

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December 2018

Wait times for endoscopic sinus surgery influence patient-reported outcome measures in patients with chronic rhinosinusitis who fulfill appropriateness criteria.

Int Forum Allergy Rhinol 2018 Dec 10. Epub 2018 Dec 10.

Division of Rhinology, Department of Otolaryngology-Head and Neck Surgery, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

Background: Previous studies on the impact of wait times for endoscopic sinus surgery (ESS) in medically recalcitrant chronic rhinosinusitis (rCRS) have not examined its influence on the 5 distinct symptoms domains of the 22-item Sino-Nasal Outcome Test (SNOT-22), and have not applied evidence-based surgical indications. Our primary study objective was to investigate the impact of ESS wait times on postoperative SNOT-22 global and symptom domain scores in patients with rCRS deemed "appropriate" surgical candidates.

Methods: This was a retrospective analysis of adult patients with rCRS undergoing ESS, categorized as "appropriate" surgical candidates. Read More

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December 2018

The American Headache Society Position Statement On Integrating New Migraine Treatments Into Clinical Practice.

Authors:

Headache 2018 Dec 10. Epub 2018 Dec 10.

Objective: To provide healthcare professionals with updated guidance in the use of novel preventive and acute treatments for migraine in adults.

Background: The principles of preventive and acute pharmacotherapy for patients with migraine have been outlined previously, but the emergence of new technologies and treatments, as well as new formulations of previously established treatments, has created a need for an updated guidance on the preventive and acute treatment of migraine.

Methods: This statement is based on a review of existing guidelines and principles for preventive and acute treatment of migraine, as well as the results of recent clinical trials of drugs and devices for these indications. Read More

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December 2018

Incidence of severe critical events in paediatric anaesthesia in the United Kingdom: secondary analysis of the anaesthesia practice in children observational trial (APRICOT study).

Anaesthesia 2018 Dec 10. Epub 2018 Dec 10.

Department of Paediatric Anaesthesia and Pain Management, University of Glasgow, Glasgow, Scotland, UK.

The anaesthesia practice in children observational trial of 31,127 patients in 261 European hospitals revealed a high (5.2%) incidence of severe critical events in the peri-operative period and wide variability in practice. A sub-analysis of the UK data was undertaken to investigate differences compared with the non-UK cohort in the incidence and nature of peri-operative severe critical events and to attempt to identify areas for quality improvement. Read More

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December 2018

Rückkehr in das Erwerbsleben nach kurativer Therapie von Kopf-Hals-Karzinomen.

Laryngorhinootologie 2018 Dec 10;97(12):838-845. Epub 2018 Dec 10.

Universitätsklinikum Leipzig AöR Klinik und Poliklinik für Hals-, Nasen-, Ohrenheilkunde.

Objective: Reintegration of cancer patients into occupational life is an important social and economic factor. Data for the "return to work" in Head and Neck Cancer (HNC) patients are sparse, especially compared with other tumor entities.

Material And Methods: In a selective literature research, original articles dealing with the theme complex "return to work in patients with HNC", between 1997 and 2018 were included and analyzed. Read More

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December 2018

Evaluating centralized technical assistance as an implementation strategy to improve cancer prevention and control.

Cancer Causes Control 2018 Dec 7. Epub 2018 Dec 7.

Prevention Research Center, Brown School, Washington University in St. Louis, One Brookings Drive, Campus, Box 1196, St. Louis, MO, 63130, USA.

Purpose: In 2015-2016, the Comprehensive Cancer Control National Partnership provided technical assistance workshops to support 22 cancer coalitions in increasing human papillomavirus (HPV) vaccination uptake and increasing colorectal cancer (CRC) screening in their local communities. As national efforts continue to invest in providing technical assistance, there is a current gap in understanding its use as a strategy to accelerate implementation of evidence-based interventions (EBIs) for cancer prevention. The objective of this study was to evaluate the impact of technical assistance on the participants' knowledge, attitudes, and skills for implementing EBIs in their local context and enhancing state team collaboration. Read More

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December 2018

"Creative Financing": Funding Evidence-Based Interventions in Human Service Systems.

J Behav Health Serv Res 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychiatry, University of California, San Diego, 9500 Gilman Drive (8012), La Jolla, CA, 92093-0812, USA.

Implementation and sustainment of evidence-based interventions (EBIs) is influenced by outer (e.g., broader environments in which organizations operate) and inner (e. Read More

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December 2018