110 results match your criteria Evidence-Based Gastroenterology[Journal]


Reconciliation of Recent Helicobacter pylori Treatment Guidelines in a Time of Increasing Resistance to Antibiotics.

Gastroenterology 2019 Apr 15. Epub 2019 Apr 15.

Department of Gastroenterology, Hepatology and infectious diseases, Otto-von-Guericke University, Magdeburg, Germany, and Ludwig Maximilian University Clinic, Med. Clinic II, Muenchen, Germany.

Increasing resistance to antibiotics, worldwide, has adverse effects on the effectiveness of standard therapies to eradicate Helicobacter pylori infection. We reviewed guidelines developed by expert groups in Europe, Canada, and the United States for the treatment of Helicobacter pylori infection. We compared the recommendations of these guidelines, reconciled them, and addressed the increasing resistance of H pylori to antibiotic therapy regimens. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085193570
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http://dx.doi.org/10.1053/j.gastro.2019.04.011DOI Listing
April 2019
3 Reads

Endoscopic transpapillary drainage in disconnected pancreatic duct syndrome after acute pancreatitis and trauma: long-term outcomes in 31 patients.

BMC Gastroenterol 2019 Apr 16;19(1):54. Epub 2019 Apr 16.

Department of Gastroenterology, Digestive Endoscopy Center, Changhai Hospital, The Second Military Medical University, 168 Changhai Road, Shanghai, 200433, China.

Background: Conventionally, disconnected pancreatic duct syndrome is treated surgically. Endoscopic management is associated with lesser morbidity and mortality than that observed with surgery and shows similar success rates. However, limited data are available in this context. Read More

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http://dx.doi.org/10.1186/s12876-019-0977-1DOI Listing
April 2019
1 Read

Current Concepts in Severe Acute and Necrotizing Pancreatitis: An Evidence-Based Approach.

Gastroenterology 2019 Feb 15. Epub 2019 Feb 15.

Department of Surgery, Amsterdam Gastroenterology and Metabolism, Amsterdam UMC, University of Amsterdam, the Netherlands.

The incidence of acute pancreatitis continues to rise, inducing substantial medical and social burden, with annual costs exceeding $2 billion in the United States alone. Although most patients develop mild pancreatitis, 20% develop severe and/or necrotizing pancreatitis, requiring advanced medical and interventional care. Morbidity resulting from local and systemic complications as well as invasive interventions result in mortality rates historically as high as 30%. Read More

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http://dx.doi.org/10.1053/j.gastro.2019.01.269DOI Listing
February 2019

Effects of Promotility Agents on Gastric Emptying and Symptoms: A Systematic Review and Meta-analysis.

Gastroenterology 2019 May 31;156(6):1650-1660. Epub 2019 Jan 31.

Evidence Based Practice Center, Mayo Clinic, Rochester, Minnesota.

Background & Aims: Studies have reported a lack of association between improvements in gastric emptying (GE) and upper gastrointestinal (UGI) symptoms with promotility drugs. However, GE test methods were suboptimal in some studies. We assessed improvements in GE and UGI symptoms in patients given promotility agents in studies with optimal or moderate test methods (scintigraphy or breath test, solid meal, >2 hours duration) compared to studies with suboptimal GE test methods. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085193034
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http://dx.doi.org/10.1053/j.gastro.2019.01.249DOI Listing
May 2019
6 Reads

Superiority of Step-up Approach vs Open Necrosectomy in Long-term Follow-up of Patients With Necrotizing Pancreatitis.

Gastroenterology 2019 03 2;156(4):1016-1026. Epub 2018 Nov 2.

Department of Surgery, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Surgery, St. Antonius Hospital, Nieuwegein, the Netherlands. Electronic address:

Background & Aims: In a 2010 randomized trial (the PANTER trial), a surgical step-up approach for infected necrotizing pancreatitis was found to reduce the composite endpoint of death or major complications compared with open necrosectomy; 35% of patients were successfully treated with simple catheter drainage only. There is concern, however, that minimally invasive treatment increases the need for reinterventions for residual peripancreatic necrotic collections and other complications during the long term. We therefore performed a long-term follow-up study. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183520
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http://dx.doi.org/10.1053/j.gastro.2018.10.045DOI Listing
March 2019
28 Reads

Evidence-Based Guidelines for Screening Individuals With a Family History of Colorectal Cancer- More Questions Than Answers.

Gastroenterology 2018 11 8;155(5):1298-1300. Epub 2018 Oct 8.

Gastroenterology Section, John D. Dingell VA Medical Center and Department of Medicine, University of Michigan School of Medicine, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.10.014DOI Listing
November 2018
1 Read

Potential Intended and Unintended Consequences of Recommending Initiation of Colorectal Cancer Screening at Age 45 Years.

Gastroenterology 2018 10 21;155(4):950-954. Epub 2018 Aug 21.

VA San Diego Health Care System and University of California, San Diego and Moores Cancer Center, La Jolla, California.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183488
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http://dx.doi.org/10.1053/j.gastro.2018.08.019DOI Listing
October 2018
6 Reads

Clinical Practice Guideline on Screening for Colorectal Cancer in Individuals With a Family History of Nonhereditary Colorectal Cancer or Adenoma: The Canadian Association of Gastroenterology Banff Consensus.

Gastroenterology 2018 11 16;155(5):1325-1347.e3. Epub 2018 Aug 16.

Division of Gastroenterology and Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.

Background & Aims: A family history (FH) of colorectal cancer (CRC) increases the risk of developing CRC. These consensus recommendations developed by the Canadian Association of Gastroenterology and endorsed by the American Gastroenterological Association, aim to provide guidance on screening these high-risk individuals.

Methods: Multiple parallel systematic review streams, informed by 10 literature searches, assembled evidence on 5 principal questions around the effect of an FH of CRC or adenomas on the risk of CRC, the age to initiate screening, and the optimal tests and testing intervals. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183488
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http://dx.doi.org/10.1053/j.gastro.2018.08.017DOI Listing
November 2018
17 Reads

An Evidence-Based Review of Statin Use in Patients With Nonalcoholic Fatty Liver Disease.

Clin Med Insights Gastroenterol 2018 10;11:1179552218787502. Epub 2018 Jul 10.

Office of Professional Affairs, Department of Pharmacy Practice, School of Pharmacy, Texas Tech University Health Sciences Center, Dallas, TX, USA.

Background: Nonalcoholic fatty liver disease (NAFLD) is a common complication in patients with metabolic syndrome. The role of statin therapy specifically for the treatment of NAFLD remains unknown. The aim of this review is to discuss outcomes of recent articles analyzing statin therapy in patients with NAFLD. Read More

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http://dx.doi.org/10.1177/1179552218787502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043943PMC
July 2018
5 Reads

Rome Foundation Working Team Report on Post-Infection Irritable Bowel Syndrome.

Gastroenterology 2019 01 28;156(1):46-58.e7. Epub 2018 Nov 28.

Department of Biochemical Engineering and Biotechnology, Faculty of Technology and Metallurgy, University of Belgrade, Belgrade, Serbia.

Background & Aims: The existence of postinfection irritable bowel syndrome (PI-IBS) has been substantiated by epidemiology studies conducted in diverse geographic and clinical settings. However, the available evidence has not been well summarized, and there is little guidance for diagnosis and treatment of PI-IBS. The ROME Foundation has produced a working team report to summarize the available evidence on the pathophysiology of PI-IBS and provide guidance for diagnosis and treatment, based on findings reported in the literature and clinical experience. Read More

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http://dx.doi.org/10.1053/j.gastro.2018.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309514PMC
January 2019
13 Reads

Development of Evidence-Based Surveillance Intervals After Radiofrequency Ablation of Barrett's Esophagus.

Gastroenterology 2018 08 13;155(2):316-326.e6. Epub 2018 Apr 13.

University of North Carolina at Chapel Hill, Department of Medicine, Division of Gastroenterology and Hepatology, Center for Esophageal Diseases and Swallowing, Chapel Hill, North Carolina. Electronic address:

Background & Aims: Barrett's esophagus (BE) recurs in 25% or more of patients treated successfully with radiofrequency ablation (RFA), so surveillance endoscopy is recommended after complete eradication of intestinal metaplasia (CEIM). The frequency of surveillance is informed only by expert opinion. We aimed to model the incidence of neoplastic recurrence, validate the model in an independent cohort, and propose evidence-based surveillance intervals. Read More

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http://dx.doi.org/10.1053/j.gastro.2018.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6067977PMC
August 2018
6 Reads

Acute Pancreatitis Guideline.

Gastroenterology 2018 Mar 2;154(4):1102. Epub 2018 Mar 2.

Section of Gastroenterology and Hepatology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

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http://dx.doi.org/10.1053/j.gastro.2018.02.029DOI Listing
March 2018
3 Reads

Endoscopic Submucosal Dissection: Indications and Application in Western Endoscopy Practice.

Gastroenterology 2018 May 2;154(7):1887-1900.e5. Epub 2018 Mar 2.

Academic Medical Centre, Department of Gastroenterology and Hepatology, Amsterdam, Netherlands.

Endoscopic submucosal dissection was developed in Japan, early in this century, to provide a minimally invasive yet curative treatment for the large numbers of patients with early gastric cancer identified by the national screening program. Previously, the majority of these patients were treated surgically at substantial cost and with significant risk of short- and long-term morbidity. En-bloc excision of these early cancers, most with a limited risk of nodal metastasis, allowed complete staging of the tumor, stratification of the subsequent therapeutic approach, and potential cure. Read More

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http://dx.doi.org/10.1053/j.gastro.2018.01.068DOI Listing
May 2018
3 Reads

Controversies in Endoscopic Eradication Therapy for Barrett's Esophagus.

Gastroenterology 2018 05 16;154(7):1861-1875.e1. Epub 2018 Feb 16.

Division of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

Advances in endoscopic eradication therapy for Barrett's Esophagus-associated neoplasia have resulted in a significant paradigm shift in the diagnosis and management of this complex disease. A robust body of literature critically evaluating outcomes of resection and ablative strategies has allowed gastroenterologists to make quality, evidence-based decisions for their patients. Despite this progress, there are still many unanswered questions and challenges that remain. Read More

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http://dx.doi.org/10.1053/j.gastro.2017.12.045DOI Listing
May 2018
6 Reads

Initial Medical Treatment of Acute Pancreatitis: American Gastroenterological Association Institute Technical Review.

Gastroenterology 2018 Mar 6;154(4):1103-1139. Epub 2018 Feb 6.

Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1053/j.gastro.2018.01.031DOI Listing
March 2018
4 Reads

Best Practice Update: Incorporating Psychogastroenterology Into Management of Digestive Disorders.

Gastroenterology 2018 Apr 1;154(5):1249-1257. Epub 2018 Feb 1.

Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Chronic digestive diseases, including irritable bowel syndrome, gastroesophageal reflux disease, and inflammatory bowel diseases, cannot be disentangled from their psychological context-the substantial burden of these diseases is co-determined by symptom and disease severity and the ability of patients to cope with their symptoms without significant interruption to daily life. The growing field of psychogastroenterology focuses on the application of scientifically based psychological principles and techniques to the alleviation of digestive symptoms. In this Clinical Practice Update, we describe the structure and efficacy of 2 major classes of psychotherapy-cognitive behavior therapy and gut-directed hypnotherapy. Read More

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http://dx.doi.org/10.1053/j.gastro.2018.01.045DOI Listing
April 2018
6 Reads

American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis.

Gastroenterology 2018 Mar 3;154(4):1096-1101. Epub 2018 Feb 3.

Division of Gastroenterology, McGill University, Montréal, Québec, Canada.

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http://dx.doi.org/10.1053/j.gastro.2018.01.032DOI Listing
March 2018
5 Reads

Consensus Recommendations for Evaluation, Interpretation, and Utilization of Computed Tomography and Magnetic Resonance Enterography in Patients With Small Bowel Crohn's Disease.

Gastroenterology 2018 Mar 10;154(4):1172-1194. Epub 2018 Jan 10.

Division of GI Surgery, Northwestern Medicine, Chicago, Illinois.

Computed tomography and magnetic resonance enterography have become routine small bowel imaging tests to evaluate patients with established or suspected Crohn's disease, but the interpretation and use of these imaging modalities can vary widely. A shared understanding of imaging findings, nomenclature, and utilization will improve the utility of these imaging techniques to guide treatment options, as well as assess for treatment response and complications. Representatives from the Society of Abdominal Radiology Crohn's Disease-Focused Panel, the Society of Pediatric Radiology, the American Gastroenterological Association, and other experts, systematically evaluated evidence for imaging findings associated with small bowel Crohn's disease enteric inflammation and established recommendations for the evaluation, interpretation, and use of computed tomography and magnetic resonance enterography in small bowel Crohn's disease. Read More

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http://dx.doi.org/10.1053/j.gastro.2017.11.274DOI Listing
March 2018
3 Reads

Efficacy of Laparoscopic Nissen Fundoplication vs Transoral Incisionless Fundoplication or Proton Pump Inhibitors in Patients With Gastroesophageal Reflux Disease: A Systematic Review and Network Meta-analysis.

Gastroenterology 2018 04 3;154(5):1298-1308.e7. Epub 2018 Jan 3.

Division of General Surgery, University of South Florida, Tampa, Florida.

Background & Aims: The effects of transoral incisionless fundoplication (TIF) and laparoscopic Nissen fundoplication (LNF) have been compared with those of proton pump inhibitors (PPIs) or a sham procedure in patients with gastroesophageal reflux disease (GERD), but there has been no direct comparison of TIF vs LNF. We performed a systematic review and network meta-analysis of randomized controlled trials to compare the relative efficacies of TIF vs LNF in patients with GERD.

Methods: We searched publication databases and conference abstracts through May 10, 2017 for randomized controlled trials that compared the efficacy of TIF or LNF with that of a sham procedure or PPIs in patients with GERD. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085183000
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http://dx.doi.org/10.1053/j.gastro.2017.12.021DOI Listing
April 2018
7 Reads
1 Citation
16.720 Impact Factor

Neuromodulators for Functional Gastrointestinal Disorders (Disorders of Gut-Brain Interaction): A Rome Foundation Working Team Report.

Gastroenterology 2018 Mar 22;154(4):1140-1171.e1. Epub 2017 Dec 22.

Laboratory for Brain-Gut Axis Studies, Translational Research Center for Gastrointestinal Disorders, University of Leuven, Leuven, Belgium.

Background & Aims: Central neuromodulators (antidepressants, antipsychotics, and other central nervous system-targeted medications) are increasingly used for treatment of functional gastrointestinal disorders (FGIDs), now recognized as disorders of gut-brain interaction. However, the available evidence and guidance for the use of central neuromodulators in these conditions is scanty and incomplete. In this Rome Foundation Working Team report, a multidisciplinary team summarized available research evidence and clinical experience to provide guidance and treatment recommendations. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085173671
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http://dx.doi.org/10.1053/j.gastro.2017.11.279DOI Listing
March 2018
39 Reads

American Gastroenterological Association Institute Guideline on Therapeutic Drug Monitoring in Inflammatory Bowel Disease.

Gastroenterology 2017 09 3;153(3):827-834. Epub 2017 Aug 3.

Division of Gastroenterology, University of California, San Diego, La Jolla, California.

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http://dx.doi.org/10.1053/j.gastro.2017.07.032DOI Listing
September 2017
61 Reads

Therapeutic Drug Monitoring in Inflammatory Bowel Disease: A Patient Guide.

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Gastroenterology 2017 Sep 31;153(3):860-861. Epub 2017 Jul 31.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085173596
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http://dx.doi.org/10.1053/j.gastro.2017.07.037DOI Listing
September 2017
22 Reads

American Gastroenterological Association Institute Technical Review on the Role of Elastography in Chronic Liver Diseases.

Gastroenterology 2017 05;152(6):1544-1577

Division of Gastroenterology and Hepatology, Cleveland VA Medical Center and University Hospitals, Case Western Reserve University, Cleveland, Ohio.

Chronic liver diseases (CLDs), due to chronic hepatitis C; hepatitis B; nonalcoholic fatty liver diseases (NAFLD); and alcoholic liver disease, are a leading cause of morbidity and mortality globally. Early identification of patients with cirrhosis at high risk of progression to liver-related complications may facilitate timely care and improve outcomes. With risks and misclassification associated with invasive tests, such as liver biopsy, noninvasive imaging modalities for liver fibrosis assessment have gained popularity. Read More

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http://dx.doi.org/10.1053/j.gastro.2017.03.016DOI Listing
May 2017
11 Reads

American Gastroenterological Association Institute Guideline on the Role of Elastography in the Evaluation of Liver Fibrosis.

Gastroenterology 2017 05;152(6):1536-1543

Division of Gastroenterology and Hepatology, Cleveland VA Medical Center and University Hospitals, Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1053/j.gastro.2017.03.017DOI Listing
May 2017
3 Reads

Costs and quality of life of small-incision open cholecystectomy and laparoscopic cholecystectomy - an expertise-based randomised controlled trial.

BMC Gastroenterol 2017 Apr 8;17(1):48. Epub 2017 Apr 8.

Department of Surgery, Umeå University, SE-901 85, Umeå, Sweden.

Background: Health care providers need solid evidence based data on cost differences between alternative surgical procedures for common surgical disorders. We aimed to compare small-incision open cholecystectomy (SIOC) and laparoscopic cholecystectomy (LC) concerning costs and health-related quality of life using data from an expertise-based randomised controlled trial.

Methods: Patients scheduled for cholecystectomy were assigned to undergo LC or SIOC performed by surgeons in two different expert groups. Read More

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http://bmcgastroenterol.biomedcentral.com/articles/10.1186/s
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http://dx.doi.org/10.1186/s12876-017-0601-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385047PMC
April 2017
5 Reads

The Risks and Benefits of Long-term Use of Proton Pump Inhibitors: Expert Review and Best Practice Advice From the American Gastroenterological Association.

Gastroenterology 2017 03;152(4):706-715

Divison of Gastroenterology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Background & Aims: The purpose of this review is to evaluate the risks associated with long-term use of proton pump inhibitors (PPIs), focusing on long-term use of PPIs for three common indications: gastroesophageal reflux disease (GERD), Barrett's esophagus (BE), and non-steroidal anti-inflammatory drug (NSAID) bleeding prophylaxis.

Methods: The recommendations outlined in this review are based on expert opinion and on relevant publications from PubMed, EMbase, and the Cochrane library (through July 2016). To identify relevant ongoing trials, we queried clinicaltrials. Read More

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http://dx.doi.org/10.1053/j.gastro.2017.01.031DOI Listing
March 2017
20 Reads

Clinical Practice Update: Expert Review on Endoscopic Bariatric Therapies.

Gastroenterology 2017 03 29;152(4):716-729. Epub 2017 Jan 29.

Division of Gastroenterology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

Background & Aims: Multiple endoscopic bariatric therapies (EBTs) currently are being evaluated or are in clinical use in the United States. EBTs are well positioned to fill an important gap in the management of obesity and metabolic disease. The purpose of this expert review is to update gastroenterologists on these therapies and provide practice advice on how to incorporate them into clinical practice. Read More

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http://dx.doi.org/10.1053/j.gastro.2017.01.035DOI Listing
March 2017
3 Reads

The cut-off value of tumor size and appropriate timing of follow-up for management of minimal EUS-suspected gastric gastrointestinal stromal tumors.

BMC Gastroenterol 2017 Jan 11;17(1). Epub 2017 Jan 11.

Department of Gastrointestinal Surgery, Peking University People's Hospital, Beijing, 100044, People's Republic of China.

Backgroud: The detectable rate of minimal gastric GISTs has continuously increased. While the surveillance and management of GIST <2 cm have been deemed controversial or lack evidence-based approaches.  The aim of the current study is to propose a cut-off value of tumor size for treatment policy and the appropriate timing for endoscopic ultrasonography (EUS) follow-up in the minimal EUS-suspected gastric GIST patients. Read More

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http://dx.doi.org/10.1186/s12876-016-0567-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5225611PMC
January 2017
10 Reads

American Gastroenterological Association Institute Technical Review on Initial Testing and Management of Acute Liver Disease.

Gastroenterology 2017 Feb 4;152(3):648-664.e5. Epub 2017 Jan 4.

Division of Gastroenterology and Hepatology, Department of Medicine, Case and VA Medical Center, Case Western Reserve University, Cleveland, Ohio.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163554
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http://dx.doi.org/10.1053/j.gastro.2016.12.027DOI Listing
February 2017
7 Reads

American Gastroenterological Association Institute Guidelines for the Diagnosis and Management of Acute Liver Failure.

Gastroenterology 2017 Feb 2;152(3):644-647. Epub 2017 Jan 2.

Division of Gastroenterology, Cleveland VA Medical Center and University Hospitals, Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1053/j.gastro.2016.12.026DOI Listing
February 2017
4 Reads

Managing Crohn's Disease After Surgery: A Patient Guide.

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Gastroenterology 2017 01 26;152(1):296-297. Epub 2016 Nov 26.

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http://dx.doi.org/10.1053/j.gastro.2016.11.039DOI Listing
January 2017
2 Reads

American Gastroenterological Association Institute Guideline on the Management of Crohn's Disease After Surgical Resection.

Gastroenterology 2017 01 10;152(1):271-275. Epub 2016 Nov 10.

Minneapolis VA Health Care System, University of Minnesota, Minneapolis, Minnesota.

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http://dx.doi.org/10.1053/j.gastro.2016.10.038DOI Listing
January 2017
13 Reads

American Gastroenterological Association Institute Technical Review on the Management of Crohn's Disease After Surgical Resection.

Gastroenterology 2017 01 10;152(1):277-295.e3. Epub 2016 Nov 10.

Divisions of Gastroenterology and Biomedical Informatics, Department of Medicine, University of California, San Diego, La Jolla, California.

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http://dx.doi.org/10.1053/j.gastro.2016.10.039DOI Listing
January 2017
5 Reads

Etiology and Treatment of Pain and Psychosocial Issues in Patients With Inflammatory Bowel Diseases.

Gastroenterology 2017 Feb 2;152(2):430-439.e4. Epub 2016 Nov 2.

Division of Gastroenterology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania. Electronic address:

There is increasing evidence that brain-gut interactions are altered during development of inflammatory bowel diseases (IBDs). Understanding the relationship between the neurobiology, psychological symptoms, and social ramifications of IBD can guide comprehensive care for the whole patient. The most common psychological conditions in patients with IBD are chronic abdominal pain, anxiety, and depression. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163528
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http://dx.doi.org/10.1053/j.gastro.2016.10.036DOI Listing
February 2017
9 Reads

Helicobacter pylori Eradication?

Authors:
Alberto Donzelli

Gastroenterology 2016 10 30;151(4):773-4. Epub 2016 Aug 30.

Area of Education for Appropriateness and Evidence Based Medicine, Health Protection Agency, Metropolitan City of Milan, Milan, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085163489
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http://dx.doi.org/10.1053/j.gastro.2016.05.059DOI Listing
October 2016
4 Reads

Childhood Functional Gastrointestinal Disorders: Neonate/Toddler.

Gastroenterology 2016 Feb 15. Epub 2016 Feb 15.

Center for Motility and Functional Gastrointestinal Disorders, Boston Children's Hospital, Boston Ma, USA.

In 2006, a consensus concerning functional gastrointestinal intestinal disorders (FGIDs) in infants and toddlers was described. At that time little evidence regarding epidemiology, pathophysiology, diagnostic work-up, treatment strategies and follow-up was available. Consequently the criteria for the clinical entities were more experience than evidence based. Read More

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http://dx.doi.org/10.1053/j.gastro.2016.02.016DOI Listing
February 2016
52 Reads

The Intestinal Microenvironment and Functional Gastrointestinal Disorders.

Gastroenterology 2016 Feb 18. Epub 2016 Feb 18.

Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, the Netherlands.

For decades, interactions between the enteric neuromuscular apparatus and the central nervous system have served as the primary focus of pathophysiological research in the functional gastrointestinal disorders. The accumulation of patient reports, as well as clinical observations, has belatedly led to an interest in the role of various luminal factors and their interactions with each other and the host in functional gastrointestinal disorders. Most prominent among these factors has been the role of food. Read More

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http://dx.doi.org/10.1053/j.gastro.2016.02.028DOI Listing
February 2016
13 Reads

An appraisal of clinical practice guidelines for constipation: a right attitude towards to guidelines.

BMC Gastroenterol 2016 May 4;16(1):52. Epub 2016 May 4.

Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, No. 305 East Zhongshan Road, Nanjing, 210002, China.

Background: Clinical practice guidelines (CPGs) are formally developed statements that assist users to provide proper health care for a kind of disease and play a significant contribution in healthcare system. This study report the methodological quality of CPGs on constipation.

Methods: The "Appraisal of Guidelines and Research and Evaluation" (AGREEII) instrument was developed to determine the quality of CPGs. Read More

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http://dx.doi.org/10.1186/s12876-016-0466-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855801PMC
May 2016
37 Reads

Evidence-Based Therapeutic Options for Hepatorenal Syndrome.

Gastroenterology 2016 Apr 27;150(4):1031-3. Epub 2016 Feb 27.

Division of Gastroenterology, University of Michigan, Ann Arbor, Michigan.

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http://dx.doi.org/10.1053/j.gastro.2016.02.050DOI Listing
April 2016
7 Reads

A randomised controlled trial of a Mediterranean Dietary Intervention for Adults with Non Alcoholic Fatty Liver Disease (MEDINA): study protocol.

BMC Gastroenterol 2016 Feb 2;16:14. Epub 2016 Feb 2.

Department of Rehabilitation, La Trobe University, Nutrition and Sports, Kingsbury Drive, Bundoora, Australia.

Background: Non-alcoholic fatty liver disease, the most prevalent liver disease in developed countries, remains difficult to manage with no proven safe and effective pharmacotherapy available. While weight reduction is the most commonly practiced treatment strategy, this is difficult to both achieve and/or maintain in the majority. Furthermore evidence-based dietary recommendations to guide the nutritional management of these patients are lacking. Read More

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http://dx.doi.org/10.1186/s12876-016-0426-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736175PMC
February 2016
58 Reads

Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma.

Gastroenterology 2016 Apr 12;150(4):835-53. Epub 2016 Jan 12.

Division of Gastroenterology, Department of Medicine, Toronto General Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada.

Evidence-based management of patients with hepatocellular carcinoma (HCC) is key to their optimal care. For individuals at risk for HCC, surveillance usually involves ultrasonography (there is controversy over use of biomarkers). A diagnosis of HCC is made based on findings from biopsy or imaging analyses. Read More

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http://www.usahealthsystem.com/workfiles/physicians_docs/cli
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http://linkinghub.elsevier.com/retrieve/pii/S001650851600007
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http://dx.doi.org/10.1053/j.gastro.2015.12.041DOI Listing
April 2016
5 Reads

American Gastroenterological Association Institute Guideline on the Medical Management of Microscopic Colitis.

Gastroenterology 2016 Jan 14;150(1):242-6; quiz e17-8. Epub 2015 Nov 14.

McMaster University, Hamilton, Ontario, Canada; Evidence-Based Dentistry Unit, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.

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http://dx.doi.org/10.1053/j.gastro.2015.11.008DOI Listing
January 2016
11 Reads

American Gastroenterological Association Institute Technical Review on the Medical Management of Microscopic Colitis.

Gastroenterology 2016 Jan 14;150(1):247-274.e11. Epub 2015 Nov 14.

McMaster University, Hamilton, Ontario, Canada; Evidence-Based Dentistry Unit, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.

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https://linkinghub.elsevier.com/retrieve/pii/S00165085150162
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http://dx.doi.org/10.1053/j.gastro.2015.11.006DOI Listing
January 2016
7 Reads

Measuring the quality of Barrett's esophagus management with measures that are high quality.

Gastroenterology 2015 Nov 15;149(6):1298-301. Epub 2015 Sep 15.

Durham Veterans Administration Medical Center and Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1053/j.gastro.2015.09.006DOI Listing
November 2015
6 Reads

Increasing the Impact of Randomized, Controlled Trials in Gastrointestinal Endoscopy.

Gastroenterology 2015 Sep 27;149(3):521-5. Epub 2015 Jul 27.

Division of Gastroenterology and Hepatology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2015.07.022DOI Listing
September 2015
3 Reads

AGA Clinical Practice Guidelines: Robust, Evidence-Based Tools for Guiding Clinical Care Decisions.

Gastroenterology 2015 Aug 29;149(2):493-5. Epub 2015 Jun 29.

Department of Medicine, Fox Chase Cancer Center, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1053/j.gastro.2015.06.040DOI Listing
August 2015
8 Reads

Characterization of Serum Cytokine Profile in Predominantly Colonic Inflammatory Bowel Disease to Delineate Ulcerative and Crohn's Colitides.

Clin Med Insights Gastroenterol 2015 6;8:29-44. Epub 2015 May 6.

Laboratory of Inflammatory Bowel Disease Research, Department of Biochemistry and Cancer Biology, Meharry Medical College School of Medicine, Nashville, Tennessee. ; Department of General Surgery, Colon and Rectal Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee. ; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, Tennessee.

Background: As accessible diagnostic approaches fail to differentiate between ulcerative colitis (UC) and Crohn's colitis (CC) in one-third of patients with predominantly colonic inflammatory bowel disease (IBD), leading to inappropriate therapy, we aim to investigate the serum cytokine levels in these patients in search of molecular biometric markers delineating UC from CC.

Methods: We measured 38 cytokines, chemokines, and growth factors using magnetic-bead-based multiplex immunoassay in 25 UC patients, 28 CC patients, and 30 controls. Our results are compared with those from a review of current literature regarding advances in serum cytokine profiles and associated challenges preventing their use for diagnostic/prognostic purposes. Read More

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http://dx.doi.org/10.4137/CGast.S20612DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459555PMC
June 2015
71 Reads

Laparoscopic versus open appendectomy in patients with suspected appendicitis: a systematic review of meta-analyses of randomised controlled trials.

BMC Gastroenterol 2015 Apr 15;15:48. Epub 2015 Apr 15.

Department for Evidence-based health services research, Institute for Research in Operative Medicine, Witten/Herdecke University, Ostmerheimer Str. 200 (building 38), 51109, Cologne, Germany.

Background: Several systematic reviews (SRs) of randomised controlled trials (RCTs) comparing laparoscopic versus open appendectomy have been published, but there has been no overview of SRs of these two interventions. This overview (review of review) aims to summarise the results of such SRs in order to provide the most up to date evidence, and to highlight discordant results.

Methods: Medline, Embase, Cinahl, the Cochrane Database of Systematic Reviews and the Database of Abstracts of Reviews of Effects were searched for SRs published up to August 2014. Read More

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http://dx.doi.org/10.1186/s12876-015-0277-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399217PMC
April 2015
3 Reads