49,821 results match your criteria Evaluation of Gestation


Induction of Labor at 39 Weeks of Gestation vs. Expectant Management for Low-Risk Nulliparous Women: A Cost-Effectiveness Analysis.

Am J Obstet Gynecol 2019 Feb 12. Epub 2019 Feb 12.

Oregon Health & Science University, Department of Obstetrics and Gynecology. Portland, OR.

Background: A large, recent multicenter trial found that induction of labor at 39 weeks for low-risk nulliparous women was not associated with an increased risk of cesarean delivery or adverse neonatal outcomes.

Objective: We sought to examine the cost-effectiveness and outcomes associated with induction of labor at 39 weeks versus expectant management for low-risk nulliparous women in the United States.

Study Design: A cost-effectiveness model using TreeAge software was designed to compare outcomes in women who were induced at 39 weeks versus expectantly managed. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.02.017DOI Listing
February 2019

Impact of pharmacogenetics and pregnancy on tenofovir and emtricitabine pharmacokinetics.

Pharmacogenomics 2019 Feb 15. Epub 2019 Feb 15.

Department of Molecular & Clinical Pharmacology, University of Liverpool, Liverpool, UK.

Aim: Treatment and prevention of mother-to-child transmission of HIV in pregnancy utilizes tenofovir (TFV) and emtricitabine (FTC) as NRTI backbone in combination with a third agent from a different class. We hypothesized that combined effect of pregnancy and pharmacogenetics significantly changes TFV and FTC pharmacokinetics (PK). Therefore, this study aims to evaluate the role of SNPs of transporters (ABCC2 and ABCC4) on TFV and FTC PK during pregnancy. Read More

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http://dx.doi.org/10.2217/pgs-2018-0111DOI Listing
February 2019

[Establishment and one-year evaluation of an internal medicine consultation in a maternity].

Sante Publique 2018 September October;30(5):671-677

Objective: In the obstetric medicine movement and in response to requests for appointments in internal medicine by obstetricians and midwives, we created an internal medicine consultation within the maternity ward of our General Hospital, and provide feedback after 1 year.

Methods: This retrospective descriptive study took place at the Robert Ballanger Intercommunal Hospital Center in Aulnay-sous-Bois in Seine-Saint-Denis (France) between 3rd March 2016 and 9th March 2017, the first year of the internal medicine consultation, one afternoon every 15 days, in the maternity level 2b.

Results: Out of 121 appointments, 93 consultations were conducted for 63 patients. Read More

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http://dx.doi.org/10.3917/spub.186.0671DOI Listing
February 2019

How can we make pregnancy safe for women with Turner syndrome?

Am J Med Genet C Semin Med Genet 2019 Feb 15. Epub 2019 Feb 15.

Endocrinology Department, Saint Antoine Hospital, Centre de Référence des Maladies Endocrines Rares de la Croissance, Filière FIRENDO, ENDO-ERN, Paris, France.

Pregnancy is a crucial issue in patients with Turner syndrome (TS). Although natural pregnancies have been reported in 4-7% of TS patients, most women will need assisted reproductive technologies (ART) with oocyte donation. The main issue is the maternal mortality rate that is higher than in the general population. Read More

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http://dx.doi.org/10.1002/ajmg.c.31682DOI Listing
February 2019

Claims for contraceptive services among young women filling chronic opioid prescriptions.

Contraception 2019 Feb 11. Epub 2019 Feb 11.

Division of Pharmaceutical Evaluation and Policy, Department of Pharmacy Practice, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address:

Objective: To describe claims for contraceptive services among reproductive aged women filling chronic opioid prescriptions.

Study Design: Using a large US commercial claims database, IMS Lifelink+, we identified women aged 15-44years who filled chronic opioid prescriptions (defined as a 90day supply of opioids without a 30day gap over a 180day time period) and had continuous pharmacy and medical enrollment for at least 90days prior to and 180days following their index opiod prescription. After excluding women with any claims for pregnancy-related services, we describe claims for contraceptive prescriptions and used multivariable logistic regression to identify variables associated with women filling chronic opioids without any contraceptive claims. Read More

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http://dx.doi.org/10.1016/j.contraception.2019.01.004DOI Listing
February 2019

The incidence of unexpected poor ovarian response in Chinese young women.

Medicine (Baltimore) 2019 Feb;98(7):e14379

School of Medical and Life Science/Reproductive & Women-Children Hospital, Chengdu University of Traditional Chinese Medicine.

Unexpected poor ovarian response (UPOR) is a problem for both clinicians and infertile couples, because our understanding of this situation is limited. This article investigated incidence of UPOR in women <35 years with normal ovarian reserve function with further analysis.This is a retrospective study, which included 567 women who accepted their first IVF-ET/ICSI. Read More

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http://dx.doi.org/10.1097/MD.0000000000014379DOI Listing
February 2019

An evaluation of sexually transmitted infection and odds of preterm or early term birth using propensity score matching.

Sex Transm Dis 2019 Feb 11. Epub 2019 Feb 11.

California Preterm Birth Initiative, University of California San Francisco, San Francisco, California, USA.

Background: Few studies have examined the relationship between sexually transmitted infections (STIs) and preterm birth (<37 weeks gestation) by subtype (<32 weeks, 32 - 36 weeks, spontaneous, provider-initiated). Here, we evaluate the odds of preterm (by subtype) and early term (37 and 38 weeks gestation) birth in women with an STI compared to a propensity score matched reference population.

Methods: The sample was selected from California births in 2007-2012. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000985DOI Listing
February 2019

Evaluation of an improved tool for non-invasive prediction of neonatal respiratory morbidity based on fully automated fetal lung ultrasound analysis.

Sci Rep 2019 Feb 13;9(1):1950. Epub 2019 Feb 13.

BCNatal - Barcelona Center for Maternal-Fetal and Neonatal Medicine (Hospital Clínic and Hospital Sant Joan de Deu, University of Barcelona), Barcelona, Spain.

The objective of this study was to evaluate the performance of a new version of quantusFLM®, a software tool for prediction of neonatal respiratory morbidity (NRM) by ultrasound, which incorporates a fully automated fetal lung delineation based on Deep Learning techniques. A set of 790 fetal lung ultrasound images obtained at 24 + 0-38 + 6 weeks' gestation was evaluated. Perinatal outcomes and the occurrence of NRM were recorded. Read More

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http://www.nature.com/articles/s41598-019-38576-w
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http://dx.doi.org/10.1038/s41598-019-38576-wDOI Listing
February 2019
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EQUIPTT: The Evaluation of the QUiPP app for Triage and Transfer protocol for a cluster randomised trial to evaluate the impact of the QUiPP app on inappropriate management for threatened preterm labour.

BMC Pregnancy Childbirth 2019 Feb 13;19(1):68. Epub 2019 Feb 13.

Division of Women's Health, Faculty of Life Sciences & Medicine, King's College London, 10th Floor, North Wing, St Thomas's Hospital Campus, London, SE1 7EH, UK.

Background: Accurate diagnosis of preterm labour is needed to ensure correct management of those most at risk of preterm birth and to prevent the maternal and fetal risks incurred by unnecessary interventions given to the large majority of women, who do not deliver within a week of presentation. Intervention "just-in-case" results in many avoidable admissions, women being transferred out of their local hospital unnecessarily and most women receiving unwarranted drugs, such as steroids and tocolytics. It also precludes appropriate transfers for others as neonatal cots are blocked pre-emptively, resulting in more dangerous ex-utero transfers. Read More

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http://dx.doi.org/10.1186/s12884-019-2210-1DOI Listing
February 2019

Using fetal scalp stimulation with Doppler ultrasonography to enhance intermittent auscultation in low-resource settings: a diagnostic trial from Tanzania.

BMC Pregnancy Childbirth 2019 Feb 13;19(1):71. Epub 2019 Feb 13.

Hubert-Yeargan Center for Global Health, Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC, USA.

Background: Hypoxia during labor contributes to 2.2 million intrapartum and early neonatal deaths each year. An additional 0. Read More

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http://dx.doi.org/10.1186/s12884-019-2212-zDOI Listing
February 2019

A free-choice high-fat high-sucrose diet induces hyperphagia, obesity, and cardiovascular dysfunction in female cycling and pregnant rats.

Am J Physiol Regul Integr Comp Physiol 2019 Feb 13. Epub 2019 Feb 13.

Department of Physiology and Anatomy, University of North Texas Health Science Center, United States.

The main objective of these studies was to characterize metabolic, body composition, and cardiovascular responses to a free-choice high-fat high-sucrose diet in female cycling and pregnant rats. In the non-pregnant state, female Sprague-Dawley rats offered a 3-week free-choice high-fat high-sucrose diet had greater energy intake, adiposity, serum leptin and triglyceride concentrations compared to rats fed with standard chow, and developed glucose intolerance. In addition, choice diet-fed rats had larger cardiac ventricular weights, smaller kidney and pancreas weights, and higher blood pressure than chow-fed rats, but they did not exhibit resistance artery endothelial dysfunction. Read More

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http://dx.doi.org/10.1152/ajpregu.00391.2018DOI Listing
February 2019

Evaluation of Mothers' Perceptions of a Technology-Based Supportive Educational Parenting Program (Part 2): Qualitative Study.

J Med Internet Res 2019 Feb 13;21(2):e11065. Epub 2019 Feb 13.

National University of Singapore, Singapore, Singapore.

Background: Transitioning into parenthood can be stressful as parents struggle to cope with new parenting responsibilities. Although perinatal care in hospitals aims to improve parental outcomes, there is a general consensus that it is suboptimal and insufficient. Therefore, many studies have designed intervention methods to supplement support for parents during this stressful period. Read More

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http://dx.doi.org/10.2196/11065DOI Listing
February 2019

Piloting a Telephone Based Health Coaching Program for Pregnant Women: A Mixed Methods Study.

Matern Child Health J 2019 Feb 12. Epub 2019 Feb 12.

Department of Obstetrics and Gynaecology, Royal North Shore Hospital, St Leonards, NSW, Australia.

Objectives Get Healthy in Pregnancy (GHiP) is a telephone based lifestyle coaching service for pregnant women, in New South Wales, Australia. GHiP had two service options; a telephone-based health coaching program consisting of up to 10 calls and information only (including one call). This study sought to compare the outcomes of the two GHiP options, to determine the characteristics of women likely to use the service and to explore the feedback from women and health professionals. Read More

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http://dx.doi.org/10.1007/s10995-019-02735-2DOI Listing
February 2019

Proteomics and Metabolomics in Pregnancy-An Overview.

Obstet Gynecol Surv 2019 Feb;74(2):111-125

Director of Ob/Gyn Research, Texas A&M Health Science Center College of Medicine, and Departments of Pediatrics, Obstetrics & Gynecology, and Internal Medicine, Baylor Scott & White Health, Temple, TX.

Importance: Pregnancy is getting more and more complex due to increasing number of complications that may affect fetal outcomes. The introduction of newer "proteomics and metabolomics" technologies in the field of obstetrics and gynecology may allow physicians to identify possible associated etiologies that affect the mother during pregnancy and lead to associated complications affecting the offspring.

Objective: The principal objective of this review article is to provide a comprehensive evaluation of the use of proteomics and metabolomics in complicated pregnancies. Read More

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http://dx.doi.org/10.1097/OGX.0000000000000646DOI Listing
February 2019

Antenatal care as a means to increase participation in the continuum of maternal and child healthcare: an analysis of the poorest regions of four Mesoamérican countries.

BMC Pregnancy Childbirth 2019 Feb 12;19(1):66. Epub 2019 Feb 12.

Institute for Health Metrics and Evaluation, 2301 5th Ave, Suite, Seattle, WA, 600, USA.

Background: Antenatal care (ANC) is a means to identify high-risk pregnancies and educate women so that they might experience a healthier delivery and outcome. There is a lack of evidence about whether receipt of ANC is an effective strategy for keeping women in the system so they partake in other maternal and child interventions, particularly for poor women. The present analysis examines whether ANC uptake is associated with other maternal and child health behaviors in poor mothers in Guatemala, Honduras, Nicaragua, and Mexico (Chiapas). Read More

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http://dx.doi.org/10.1186/s12884-019-2207-9DOI Listing
February 2019

[Medically Assisted Reproduction in Natural Cycle: Outcome Evaluation of a Reproductive Medicine Department].

Acta Med Port 2019 Feb 1;32(1):25-29. Epub 2019 Feb 1.

Departamento de Ginecologia/Obstetrícia. Faculdade de Medicina. Universidade de Coimbra. Coimbra. Portugal.

Introduction: Medically assisted reproduction in natural cycle has been investigated, especially in women with poor response to conventional ovarian stimulation, with endometrial receptivity improvement, lower cost and possibility of successive cycles. The disadvantages are: lower profitability per treatment cycle and higher cancellation rate. The aim of this study was to determine the rate of clinical pregnancy in infertile women subjected to medically assisted reproduction in natural cycle. Read More

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http://dx.doi.org/10.20344/amp.10195DOI Listing
February 2019
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The risk of birth defects is not associated with semen parameters or mode of conception in offspring of men visiting a reproductive health clinic.

Hum Reprod 2019 Feb 12. Epub 2019 Feb 12.

Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA.

Study Question: What is the relationship between semen parameters and birth defect (BD) rates in offspring of men evaluated for infertility?

Summary Answer: Among men undergoing infertility evaluation, there is no significant relationship between semen parameters and defect rates in live or still births, even when considering mode of conception.

What Is Known Already: Approximately 15% of couples have fertility difficulties, with up to a 50% male factor contribution. An increased risk of BDs exists in couples using ART, particularly IVF and ICSI, but it is unknown if this related to the ART procedures or an underlying male factor. Read More

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http://dx.doi.org/10.1093/humrep/dez005DOI Listing
February 2019
1 Read

Neurologic Conditions: New-Onset Seizures in Adults.

FP Essent 2019 Feb;477:22-28

University of South Alabama College of Medicine Department of Family Medicine, 1601 Center Street, 2N Mobile, AL 36604.

Family physicians may be the first point of contact for adults with new-onset seizure. There are many etiologies of seizures in adults. Etiologies of provoked seizures include temporary metabolic disturbances, central nervous system infections, cerebrovascular disease, drug withdrawal, and traumatic brain injury. Read More

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February 2019
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Neurodevelopmental and behavioral consequences of perinatal exposure to the HIV drug efavirenz in a rodent model.

Transl Psychiatry 2019 Feb 11;9(1):84. Epub 2019 Feb 11.

Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition, and Behaviour, Centre for Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands.

Efavirenz is recommended as a preferred first-line drug for women of childbearing potential living with human immunodeficiency virus. Efavirenz is known for its central nervous system side effects, which are partly mediated by serotonergic actions. The neurotransmitter serotonin exerts neurotrophic effects during neurodevelopment and antenatal exposure to serotonergic agents has been linked to developmental delay. Read More

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http://dx.doi.org/10.1038/s41398-019-0420-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370772PMC
February 2019

Bronchopulmonary dysplasia: Rationale for a pathophysiological rather than treatment based approach to diagnosis.

Paediatr Respir Rev 2018 Dec 19. Epub 2018 Dec 19.

School of Human Sciences, University of Western Australia, Perth, Australia; Centre for Neonatal Research and Education, University of Western Australia, Perth, Australia. Electronic address:

Bronchopulmonary dysplasia (BPD), also known as Chronic Lung Disease (CLD), is a chronic respiratory condition of prematurity with potential life-long consequences for respiratory well-being. BPD was first described by Northway in 1967, when the mean gestation of preterm infants with BPD was 34 weeks' postmenstrual age (PMA). Survival of preterm infants at lower gestational ages has increased steadily since 1967 associated with marked improvements in respiratory management of respiratory distress syndrome. Read More

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http://dx.doi.org/10.1016/j.prrv.2018.12.002DOI Listing
December 2018

Expression, Regulation, and Function of the Calmodulin Accessory Protein PCP4/PEP-19 in Myometrium.

Reprod Sci 2019 Feb 11:1933719119828072. Epub 2019 Feb 11.

1 Department of Obstetrics and Gynecology, Division of Research, University of Kansas School of Medicine, Kansas City, KS, USA.

Objective:: Calmodulin (CaM) plays a key role in the orchestration of Ca signaling events, and its regulation is considered an important component of cellular homeostasis. The control of uterine smooth muscle function is largely dependent on the regulation of Ca and CaM signaling. The objective of this study was to investigate the expression, function, and regulation of CaM regulatory proteins in myometrium during pregnancy. Read More

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http://dx.doi.org/10.1177/1933719119828072DOI Listing
February 2019
3 Reads

Does the anti-Müllerian hormone truly reflect ovarian response in women with endometrioma?

J Obstet Gynaecol 2019 Feb 11:1-6. Epub 2019 Feb 11.

b Department of Reproductive Endocrinology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.

In this study, our aim was to determine which factor is more correlated with the number of oocytes retrieved in patients with endometrioma compared with controls undergoing in vitro fertilisation-intracytoplasmic sperm injection (IVF-ICSI) cycles: antral follicle count (AFC) or anti-Müllerian hormone (AMH). A total of 60 women with endometrioma and a control population of 60 women without endometrioma in the same period were randomly selected underwent the injection IVF-ICSI treatment. No significant differences were found between the groups in terms of age (28. Read More

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http://dx.doi.org/10.1080/01443615.2018.1533542DOI Listing
February 2019

A review of the Effects of heat stress on body temperature, milk production, and reproduction in dairy cows: a novel idea for monitoring and evaluation of heat stress.

Asian-Australas J Anim Sci 2019 Jan 4. Epub 2019 Jan 4.

Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

Heat stress exerts a substantial effect on dairy production. The temperature and humidity index (THI) is widely used to assess heat stress in dairy operations. Herein, we review the effects of high temperature and humidity on body temperature, feed intake, milk production, follicle development, estrous behavior, and pregnancy in dairy cows. Read More

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http://dx.doi.org/10.5713/ajas.18.0743DOI Listing
January 2019

[Dose-response relationship between maternal thyroid hormones in the first twenty weeks and physical and neuropsychological development of infants: A prospective cohort study in China].

Zhonghua Liu Xing Bing Xue Za Zhi 2019 Feb;40(2):180-185

Department of Maternal, Child and Adolescent Health, Anhui Provincial Key Laboratory of Population Health and Aristogenics, School of Public Health, Anhui Medical University, Hefei 230032, China.

To study the dose-response relationship between maternal thyroid hormone levels in the first twenty weeks of pregnancy and the infant physical and neuropsychological development. In this prospective cohort study, a total of 945 women and their children were included. Maternal serum samples during first half of the pregnancy were collected and analyzed for levels of thyroid hormones by using the electro-chemiluminescence immunoassay. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2019.02.011DOI Listing
February 2019
1 Read

[A Case of Uterine Rupture during Pregnancy].

Cuad Bioet 2019 Jan-Apr;30(98):67-76

Academia Alphonsiana Roma. Italia.

The article presents a rare case of uterine rupture at the 19th week of gestation, in the presence of a scar after a caesarean section practiced two years earlier. The fetus was pulled out alive, but given the gestational age, died within a few minutes. The uterus was preserved, but the woman was advised to proceed with tubal ligation and, in any case, to absolutely avoid a new pregnancy. Read More

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November 2018
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Opioid use disorder during pregnancy: An overview.

JAAPA 2019 Feb 6. Epub 2019 Feb 6.

At the time this article was written, Lillian C. Carter and Molly A. Read were students in the PA program at the University of Lynchburg in Lynchburg, Va. Laura Read is director of didactic education in the PA program at the University of Lynchburg. Joyce S. Nicholas is director of evaluation, assessment, and compliance in the PA program at the University of Lynchburg. Eric Schmidt is an assistant professor at the University of Lynchburg. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Women with opioid use disorder who become pregnant are a particularly vulnerable population and require a comprehensive treatment approach for mother and fetus. Research is continuing on opioid use disorder, effects of opioid use on the fetus, and best treatment approaches. This article reviews current recommendations and guidelines for treatment. Read More

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http://dx.doi.org/10.1097/01.JAA.0000553378.44766.1dDOI Listing
February 2019

Pono Choices: Lessons for School Leaders From the Evaluation of a Teen Pregnancy Prevention Program.

J Sch Health 2019 Feb 11. Epub 2019 Feb 11.

University of Hawaii at Manoa, 1410 Lower Campus Road #171F, Honolulu, HI 96826.

Background: The US Office of Adolescent Health (OAH) funded studies of teen pregnancy and sexually transmitted infection (STI) prevention programs in 2010. The results of a 5-year OAH study conducted in the state of Hawai'i with middle school youth has implications for school leaders in the selection and implementation of comprehensive sex education curricula yielding positive outcomes for youth.

Methods: A cluster randomized controlled trial was conducted across 34 middle school in the state of Hawai'i with 1783 student participants in pre-, post-, and 1-year follow-up surveys to determine effectiveness of a culturally responsive teen pregnancy prevention curriculum, called Pono Choices, specifically developed for youth in Hawai'i. Read More

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http://doi.wiley.com/10.1111/josh.12733
Publisher Site
http://dx.doi.org/10.1111/josh.12733DOI Listing
February 2019
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Morphology and physiology of rat placenta for toxicological evaluation.

J Toxicol Pathol 2019 Jan 15;32(1):1-17. Epub 2018 Oct 15.

Veterinary Clinical Pathology, Faculty of Veterinary Medicine Okayama University of Science, 1-3 Ikoinooka, Imabari, Ehime794-8555, Japan.

The placenta plays a pivotal role in fetal growth, and placental dysfunction and injury are associated with embryo/fetal toxicity. Histological examination of the rat placenta for safety evaluation provides valuable clues to the mechanisms of this toxicity. However, the placenta has specific and complex biological features unlike those of other organs, and placental structure dramatically changes depending on the time during the gestation period. Read More

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https://www.jstage.jst.go.jp/article/tox/32/1/32_2018-0042/_
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http://dx.doi.org/10.1293/tox.2018-0042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361663PMC
January 2019
2 Reads

Economic evaluation of artificial insemination of sex-sorted semen on a Brown Swiss dairy farm-A case study.

Anim Sci J 2019 Feb 10. Epub 2019 Feb 10.

Nippon Veterinary and Life Science University, Musashino, Tokyo, Japan.

Artificial insemination using sex-sorted semen is employed to efficiently increase the number of female dairy calves born. Previous studies have determined that using sex-sorted semen is beneficial to improve the management, but the mechanism by which it increases cattle numbers through objective indices of breeding remains unclear. This study focused on a Brown Swiss cattle herd in which frozen female sex-sorted semen was systematically employed to increase the number of cattle. Read More

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http://dx.doi.org/10.1111/asj.13156DOI Listing
February 2019

Understanding innovation in health program planning and development.

Eval Program Plann 2019 Feb 4;73:226-231. Epub 2019 Feb 4.

Texas A&M University, Center for Community Health Development, 1266 TAMU, SPH Administration Building, College Station, TX 77843, United States. Electronic address:

Introduction: A need for innovative public health programs is evident as the field adapts to address changes in health priorities and target populations. The Innovative Teen Pregnancy Prevention Program (iTP) was created to support and enable innovation in teenage pregnancy prevention, developing programs to reach the most at risk youth.

Methods: A formative evaluation was conducted to understand what innovation means in the context of program development, and examine the process of innovation. Read More

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http://dx.doi.org/10.1016/j.evalprogplan.2019.02.001DOI Listing
February 2019
1 Read

[Lupus nephritis].

Nephrol Ther 2019 Feb 7. Epub 2019 Feb 7.

Service de néphrologie, hôpital Bichat, 46, rue Henri-Huchard, 75877 Paris cedex 18, France; Université Paris Diderot, 5, rue Thomas-Mann, 75013 Paris, France; Inserm U1149, Département hospitalo-universitaire (DHU) Fibrosis-Inflammation-Remodeling (FIRE), 16, rue Henri Huchard, 75890 Paris cedex 18, France. Electronic address:

Systemic lupus erythematosus is the most characteristic of auto-immune disorders that can lead to tissue damage in many organs, including kidney. Lupus nephritis occurs in 10 to 40% of lupus patients. Its clinical hallmark is the appearance of a proteinuria as soon as a 0. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17697255183065
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http://dx.doi.org/10.1016/j.nephro.2018.11.003DOI Listing
February 2019
2 Reads

: Development and Practice-Based Evidence of a Culturally Attuned Teen Pregnancy Prevention Program for Native Youth.

Int J Environ Res Public Health 2019 Feb 6;16(3). Epub 2019 Feb 6.

School of Nursing & Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA.

A clear need exists for teen pregnancy prevention programs that are responsive to the specific needs and cultural contexts of Native American communities. Recent data indicates that the birth rate for Native teens is nearly two and a half times the rate for White teens (32.9 versus 13. Read More

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http://dx.doi.org/10.3390/ijerph16030470DOI Listing
February 2019

Introduction of Intracapsular Rotary-cut Procedures (IRCP): A Modified Hysteromyomectomy Procedures Facilitating Fertility Preservation.

J Vis Exp 2019 Jan 17(143). Epub 2019 Jan 17.

Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, China; Shenzhen Key Laboratory of Gynecological Diagnostic Technology Research, China;

Uterine fibroids are common benign tumors in the female reproductive system. A hysterectomy is the most effective treatment for symptomatic fibroids. For patients desiring pregnancy, laparoscopic intracapsular myomectomy (LM) is an alternative surgery option. Read More

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http://dx.doi.org/10.3791/58410DOI Listing
January 2019
1 Read

Serum concentrations of IGF-I/IGF-II as biomarkers of alcohol damage during foetal development and diagnostic markers of Foetal Alcohol Syndrome.

Sci Rep 2019 Feb 7;9(1):1562. Epub 2019 Feb 7.

Grup de Recerca Infancia i Entorn (GRIE), Institut d'investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Foetal Alcohol Syndrome (FAS) is the most deleterious health effect derived from alcohol consumption during pregnancy and is placed at the end of the Foetal Alcohol Spectrum Disorders (FASD). Few studies have proposed potential molecular biomarkers of physical and neurological damage associated with prenatal alcohol exposure. We prospectively recruited 55 children from 8 to 12 years old, with a prenatal assessment for ethanol exposure using meconium analysis of fatty acid ethyl esters (FAEE). Read More

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http://dx.doi.org/10.1038/s41598-018-38041-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367511PMC
February 2019
1 Read

How diet, physical activity and psychosocial well-being interact in women with gestational diabetes mellitus: an integrative review.

BMC Pregnancy Childbirth 2019 Feb 7;19(1):60. Epub 2019 Feb 7.

Institute of Higher Education and Research in Healthcare (IUFRS), University of Lausanne, 1010, Lausanne, Switzerland.

Background: Gestational Diabetes Mellitus (GDM) is associated with future cardio-metabolic risks for the mother and her child. In addition, one-third of women with recent GDM develop postpartum depression. Given these adverse impacts of GDM on the health of the mother and her offspring, it is important to intervene on modifiable factors, such as diet, physical activity, and psychosocial well-being. Read More

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http://dx.doi.org/10.1186/s12884-019-2185-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367798PMC
February 2019
1 Read

Successful rescue of antepartum eclampsia in a Chinese patient: Case report.

Medicine (Baltimore) 2019 Feb;98(6):e14301

Central Laboratory of Medicine, Maternity and Child Health Hospital of Zhenjiang, Zhenjiang, Jiangsu, P.R. China.

Rationale: Eclampsia is a life-threatening complication of pregnancy. Eclampsia is a leading cause of maternal and neonatal morbidity and mortality with most injury being associated with the seizures that mark the onset of the disease. It is vital that medical worker managing eclampsia have an understanding of the disease process. Read More

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http://dx.doi.org/10.1097/MD.0000000000014301DOI Listing
February 2019
1 Read

The results of treatment with high-dose chemotherapy and peripheral blood stem cell support for gestational trophoblastic neoplasia.

Eur J Cancer 2019 Feb 4;109:162-171. Epub 2019 Feb 4.

Department of Medical Oncology, Charing Cross Hospital Campus of Imperial College, London, UK. Electronic address:

Objective: The objective of the study was to evaluate the effect of high-dose chemotherapy (HDC) with peripheral blood stem cell support (PBSCS) on survival of patients with gestational trophoblastic neoplasia (GTN) with either refractory choriocarcinomas or a poor-prognosis placental site/epithelioid trophoblastic tumours (PSTT/ETTs).

Methods: Databases of two referral centres for gestational trophoblastic disease were searched, and 32 patients treated with HDC between 1994 and 2015 were identified. Tissue samples were retrieved for genetic evaluation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09598049193001
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http://dx.doi.org/10.1016/j.ejca.2018.12.033DOI Listing
February 2019
3 Reads

Predictors of objectively measured physical activity in 12-month-old infants: A study of linked birth cohort data with electronic health records.

Pediatr Obes 2019 Feb 6:e12512. Epub 2019 Feb 6.

Health Data Research UK, Swansea University, Swansea, UK.

Background: Physical activity (PA) levels are associated with long-term health, and levels of PA when young are predictive of adult activity levels.

Objectives: This study examines factors associated with PA levels in 12-month infants.

Method: One hundred forty-one mother-infant pairs were recruited via a longitudinal birth cohort study (April 2010 to March 2013). Read More

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http://dx.doi.org/10.1111/ijpo.12512DOI Listing
February 2019
1 Read

Abnormal lung ultrasound pattern during labor: A prospective cohort pilot study.

J Clin Ultrasound 2019 Feb 6. Epub 2019 Feb 6.

Department of Anesthesiology and Intensive Care Medicine, Jagiellonian University Medical College, Cracow, Poland.

Purpose: Lung ultrasound (LUS) examination is used to evaluate patients with acute respiratory failure. The physiological LUS pattern during labor in healthy parturients has not been well described. The aim of this study was to evaluate the LUS pattern in a cohort of healthy women during uncomplicated labor. Read More

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http://dx.doi.org/10.1002/jcu.22692DOI Listing
February 2019
1 Read

10 most important contemporary challenges in the management of SLE.

Lupus Sci Med 2019 10;6(1):e000303. Epub 2019 Jan 10.

Service de rhumatologie, Hôpitaux Universitaires de Strasbourg, Université de Strasbourg, Strasbourg, France.

From a 1-year survival of less than 50% before the discovery of glucocorticoids to over 90% at 10 years in most dedicated centres, the spectrum of SLE has profoundly evolved. Despite this improvement, several major challenges currently remain. The aim of this review is to analyse what are, according to us, the 10 most important contemporary challenges in the management of SLE. Read More

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http://lupus.bmj.com/lookup/doi/10.1136/lupus-2018-000303
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http://dx.doi.org/10.1136/lupus-2018-000303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340557PMC
January 2019
4 Reads

Deferred and referred deliveries contribute to stillbirths in the Indian state of Bihar: results from a population-based survey of all births.

BMC Med 2019 Feb 7;17(1):28. Epub 2019 Feb 7.

Public Health Foundation of India, Sector 44, Institutional Area, Gurugram, National Capital Region, India.

Background: The India Newborn Action Plan (INAP) aims for < 10 stillbirths per 1000 births by 2030. A population-based understanding of risk factors for stillbirths compared with live births that could assist with reduction of stillbirths is not readily available for the Indian population.

Methods: Detailed interviews were conducted in a representative sample of all births between January and December 2016 from 182,486 households (96. Read More

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http://dx.doi.org/10.1186/s12916-019-1265-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366028PMC
February 2019
1 Read

An evaluation of oncofertility decision support resources among breast cancer patients and health care providers.

BMC Health Serv Res 2019 Feb 6;19(1):101. Epub 2019 Feb 6.

Department of Surgery, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.

Background: Cancer patients of reproductive age are at risk of infertility as a result of their treatment. Oncofertility decision support resources can assist patients with fertility decision-making before treatment yet available oncofertility resources contain varying levels of detail and different fertility options. The key information/sections needed in oncofertility resources remain unclear. Read More

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https://bmchealthservres.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12913-019-3901-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366104PMC
February 2019
3 Reads

Histological chorioamnionitis at term according to labor onset: a prospective controlled study.

J Perinatol 2019 Feb 5. Epub 2019 Feb 5.

Department of Obstetrics & Gynecology, affiliated with the Sackler Faculty of Medicine, Tel Aviv University, the Edith Wolfson Medical Center, Holon, Israel.

Objective: To study the incidence of histological chorioamnionitis (HCA) in term pregnancies according to labor onset.

Study Design: During 2013-6, term pregnancy placentas were prospectively sent to histopathology evaluation, and compared between patients with spontaneous onset labor, pre-labor ROM, labor induction and elective cesarean deliveries.

Results: A total of 260 placentas were obtained, 65 from each group. Read More

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http://dx.doi.org/10.1038/s41372-019-0327-8DOI Listing
February 2019
1 Read

Statistical Methodology in Studies of Prenatal Exposure to Mixtures of Endocrine-Disrupting Chemicals: A Review of Existing Approaches and New Alternatives.

Environ Health Perspect 2019 Feb;127(2):26001

1 School of Public Health, Faculty of Medicine, The University of Queensland , Brisbane, Queensland, Australia.

Background: Prenatal exposures to endocrine-disrupting chemicals (EDCs) during critical developmental windows have been implicated in the etiologies of a wide array of adverse perinatal and pediatric outcomes. Epidemiological studies have concentrated on the health effects of individual chemicals, despite the understanding that EDCs act together via common mechanisms, that pregnant women are exposed to multiple EDCs simultaneously, and that substantial toxicological evidence of adverse developmental effects has been documented. There is a move toward multipollutant models in environmental epidemiology; however, there is no current consensus on appropriate statistical methods. Read More

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http://dx.doi.org/10.1289/EHP2207DOI Listing
February 2019
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Early-life exposure to household chemicals and wheezing in children.

Sci Total Environ 2019 Jan 25;663:418-425. Epub 2019 Jan 25.

Research Centre for Toxic Compounds in the Environment, Faculty of Science, Masaryk University, Kamenice 753/5, 625 00 Brno, Czech Republic; Department of Epidemiology & Public Health, University College London,1 - 19 Torrington Place, London WC1E 6BT, United Kingdom. Electronic address:

The prevalence of the asthmatic symptoms among children increases globally over the time. Reduced exposure to pathogens in early childhood and increased exposure to anthropogenic irritants result in increased risk of wheezing in children, and all of this may be related to the usage of household chemicals. Objective of this analysis thus was to study the potential effects of overall exposure to home chemicals in the early life on the phenotypes of wheezing from birth until five years of age. Read More

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http://dx.doi.org/10.1016/j.scitotenv.2019.01.254DOI Listing
January 2019
2 Reads

The impact of active delivery of the anterior arm during vacuum-assisted vaginal delivery on perineal tears: a clinical practice evaluation.

J Matern Fetal Neonatal Med 2019 Feb 3:1-5. Epub 2019 Feb 3.

a Department of Obstetrics and Gynecology , Besançon University Medical Center , Besançon , France.

Objective: Our purpose was to evaluate the impact of active delivery of the anterior arm with Couder's Maneuver (CM) during vacuum-assisted vaginal delivery (VAVD) on perineal tears. This maneuver can be beneficial because it has the advantage of reducing fetal biacromial diameter.

Methods: This monocentric retrospective study compared two non-concurrent cohorts of nulliparous women before and after implementation of a systematic CM during VAVD: Cohort 1 from 1 January to 31 December 2006 without CM and Cohort 2 from 1 January to 31 December 2016 with systematic CM. Read More

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http://dx.doi.org/10.1080/14767058.2019.1571573DOI Listing
February 2019

Comparing opium tincture and methadone for medication-assisted treatment of patients with opioid use disorder: Protocol for a multicenter parallel group noninferiority double-blind randomized controlled trial.

Int J Methods Psychiatr Res 2019 Feb 4:e1768. Epub 2019 Feb 4.

Addiction and Concurrent Disorders Group, Institute of Mental Health, Centre for Health Evaluation and Outcome Sciences, Department of Psychiatry, University of British Columbia, Vancouver, Canada.

Objectives: This is the first study to compare the safety and efficacy of opium tincture (OT) with methadone for treatment of opioid use disorder.

Methods: In this multicenter, double-blind, noninferiority controlled trial, a stratified sample of 204 participants with opioid use disorder were recruited from community outreach, drop-in centers, and triangular clinics. Participants were excluded in case of active participation in another treatment program for opioid use disorder, hypersensitivity to trial medications, pregnancy, and certain serious medical conditions. Read More

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http://dx.doi.org/10.1002/mpr.1768DOI Listing
February 2019
3.759 Impact Factor