55,706 results match your criteria Evaluation of Gestation


Ultrasound evaluation of the placenta in healthy and placental syndrome pregnancies: A systematic review.

Eur J Obstet Gynecol Reprod Biol 2021 May 4;262:45-56. Epub 2021 May 4.

Department of Obstetrics and Gynecology, Maastricht University Medical Centre (MUMC+), the Netherlands.

Introduction: An antepartum screening method to determine normal and abnormal placental function is desirable in the prevention of maternal and fetal pregnancy complications. Placental appearance can easily be obtained and evaluated using 2D ultrasonography, but surprisingly little is known about the change in placental appearance during gestation. Aim of this systematic review was to describe the antepartum placental appearance in placenta syndrome (PS) pregnancies, and to compare this to the appearance in healthy pregnancies. Read More

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Maternal Weight Gain and Pregnancy Outcomes in Twin Gestations.

Am J Obstet Gynecol 2021 May 10. Epub 2021 May 10.

Departments of Obstetrics and Gynecology, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Data on the optimal gestational weight gain (GWG) in twin pregnancies are limited. As a result, the Institute of Medicine (IOM) currently provides only provisional recommendations on GWG in this population.

Objective: To identify the optimal range of GWG in twin pregnancies and to estimate the association between inappropriate GWG and adverse pregnancy outcomes. Read More

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Combined Oral Contraceptive Pill-Induced Hypertension and Hypertensive Disorders of Pregnancy: Shared Mechanisms and Clinical Similarities.

Curr Hypertens Rep 2021 May 13;23(5):29. Epub 2021 May 13.

Division of Nephrology and Hypertension, Department of Internal Medicine, Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Mayo Clinic College of Medicine, Mayo Clinic, 200 First Street, SW, Rochester, MN, USA.

Purpose Of Review: Oral contraceptive pill-induced hypertension (OCPIH) and hypertensive disorders in pregnancy (HDP) share common risk factors and pathophysiological mechanisms, yet the bidirectional relationship between these two conditions is not well-established. We review and describe OCPIH and HDP to better understand how hormonal and metabolic imbalances affect hypertension.

Recent Findings: Oral contraceptive pills continue to be a popular method of contraception, with an incidence of OCPIH ranging from 1-8. Read More

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Three-Dimensional Live Imaging of Bovine Preimplantation Embryos: A New Method for IVF Embryo Evaluation.

Front Vet Sci 2021 26;8:639249. Epub 2021 Apr 26.

Laboratory of Theriogenology, Joint Department of Veterinary Medicine, Faculty of Agriculture, Tottori University, Tottori, Japan.

Conception rates for transferred bovine embryos are lower than those for artificial insemination. Embryo transfer (ET) is widely used in cattle but many of the transferred embryos fail to develop, thus, a more effective method for selecting bovine embryos suitable for ET is required. To evaluate the developmental potential of bovine preimplantation embryos (2-cell stage embryos and blastocysts), we have used the non-invasive method of optical coherence tomography (OCT) to obtain live images. Read More

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Modification of maternal late pregnancy sleep position: a survey evaluation of a New Zealand public health campaign.

BMJ Open 2021 May 11;11(5):e047681. Epub 2021 May 11.

Department of Obstetrics and Gynaecology, University of Auckland, Auckland, New Zealand.

Introduction: A 'Sleep-On-Side When Baby's Inside' public health campaign was initiated in New Zealand in 2018. This was in response to evidence that maternal supine going-to-sleep position was an independent risk factor for stillbirth from 28 weeks' gestation. We evaluated the success of the campaign on awareness and modification of late pregnancy going-to-sleep position through nationwide surveys. Read More

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Value of second-trimester uterine artery pulsatility index in pregnancies with systemic lupus erythematosus and/or antiphospholipid syndrome.

J Matern Fetal Neonatal Med 2021 May 12:1-7. Epub 2021 May 12.

Department of Obstetrics and Gynecology, Hospital General de Granollers, Barcelona, Spain.

Objective: To assess the value of the second trimester mean pulsatility index of the uterine arteries (MPI-UtA) to predict adverse perinatal outcome (APO) in women with systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS).

Methods: Pregnancies with either an SLE diagnosis or with primary APS controlled at our Hospital during a 10 years period were included. MPI-UtA was performed between 19-23 weeks' gestation. Read More

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Effect of L-Arginine supplementation in pregnant women with chronic hypertension and previous placenta vascular disorders receiving Aspirin prophylaxis: a randomized control trial.

Minerva Obstet Gynecol 2021 May 12. Epub 2021 May 12.

Obstetrics Unit, Mother Infant Department, University Hospital Policlinico of Modena, Modena, Italy.

Background: The aim of the study is to evaluate the effects of supplementation with Arginine (L-Arg) 3g, (together with Magnesium (Mg) 350 mg and Salicilate (Sal) 100 mg) on maternal blood pressure (BP), uterine artery doppler PI and neonatal outcomes in women with high-risk pregnancy for chronic hypertension (CH) and other previous placenta vascular disorders (PVD) already treated with low dose of aspirin (LDA), as recommended by guidelines.

Methods: We enrolled women affected by CH and other previous PVD referred to the High-Risk Clinic of the Mother-Infant Department of the University of Modena and Reggio Emilia from September 2017 to June 2019. The study design was a controlled, randomized trial of oral supplementation of L-Arg 3g (together with Mg 350 mg and Sal extract 100 mg) + LDA 100 mg/die versus only LDA 100 mg/die. Read More

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Lupus-like membranous nephropathy. Is it lupus? Report of 5 cases in a reference hospital in Mexico.

Lupus 2021 May 12:9612033211013584. Epub 2021 May 12.

Hospital Central "Dr. Ignacio Morones Prieto" and Faculty of Medicine, Universidad Autónoma de San Luis Potosí, S.L.P., México.

Lupus nephritis requires antinuclear antibodies as classification criteria. There is a group of patients with nephrotic syndrome and conclusive histopathological findings for lupus nephritis, without classification criteria for systemic lupus erythematosus (SLE) or extrarenal manifestations. These groups of patients have been described as "lupus-like" nephritis or "renal-limited lupus nephritis". Read More

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Evaluation of the use and attitudes of pregnant and postpartum women towards medicine utilization during pregnancy in the United Arab Emirates: A national cross-sectional study.

Int J Clin Pract 2021 May 11:e14344. Epub 2021 May 11.

College of Pharmacy, University of Florida, Guainseville, USA.

Introduction: Pregnancy period is of high concern to every woman. Knowledge about medication use needs to be highlighted at such a critical stage.

Objective: This study aimed to assess pregnant and postpartum women's use and attitude regarding the utilization of medications during pregnancy in the United Arab Emirates (UAE). Read More

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[Assessment of thyroid function in the preterm and/or very low birth weight newborn].

An Pediatr (Barc) 2021 May 8. Epub 2021 May 8.

Sección de Endocrinología Pediátrica, Complejo Hospitalario de Navarra, Pamplona, Navarra, España.

The screening program or early detection of congenital hypothyroidism is one of the greatest advances achieved in Pediatrics. Thyroid hormones are essential for brain development and maturation, which continue into the neonatal stage. Alterations in thyroid function in premature and underweight children in the first months of life causes irreversible damage to the central nervous system and is one of the most frequent and avoidable causes of mental retardation. Read More

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Client satisfaction and experience of telemedicine and home use of mifepristone and misoprostol for abortion up to 10 weeks' gestation at British Pregnancy Advisory Service: a cross-sectional evaluation.

Contraception 2021 May 8. Epub 2021 May 8.

British Pregnancy Advisory Service, 20 Timothy's Bridge Road, Stratford Enterprise Park, Stratford-upon-Avon, Warwickshire, CV37 9BF, UK. Electronic address:

Objective: Evaluate satisfaction and experience with telemedicine consultation and home use of mifepristone and misoprostol for abortion to 10 weeks' gestation.

Study Design: Cross-sectional evaluation of British Pregnancy Advisory Service (BPAS) clients who used mifepristone and misoprostol at home from 11 May to 10 July 2020. We sent a text message with a link to a web-survey 2-3 weeks postabortion. Read More

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A Smartphone App (TRIANGLE) to Change Cardiometabolic Risk Behaviors in Women Following Gestational Diabetes Mellitus: Intervention Mapping Approach.

JMIR Mhealth Uhealth 2021 May 11;9(5):e26163. Epub 2021 May 11.

Diabetes Research Group, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, Munich, Germany.

Background: Gestational diabetes mellitus (GDM) is the most common complication during pregnancy and is associated with an increased risk for the development of cardiometabolic diseases. Behavioral interventions can reduce this risk, but current solutions insufficiently address the requirements for such a program. The systematic development of a scalable mobile health (mHealth) promotion program for mothers during the first years post-GDM may contribute to solving this problem. Read More

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A Rare Case of Early Transformation of Gestational Trophoblastic Neoplasia Following Molar Pregnancy.

Am J Case Rep 2021 May 11;22:e930789. Epub 2021 May 11.

Department of Obstetrics and Gynecology, Faculty of Medicine, Padjadjaran University - Dr. Hasan Sadikin Hospital, Bandung, Indonesia.

BACKGROUND Gestational trophoblastic disease (GTD) encompasses a group of disorders that arise from abnormal growth of trophoblastic tissue. The spectrum of GTD includes 2 major groups: benign and malignant. The benign form is a hydatidiform mole, either complete or partial; the malignant forms, referred to as gestational trophoblastic neoplasia (GTN), consist of invasive moles, choriocarcinomas, placental site trophoblastic tumors, and epithelioid trophoblastic tumors. Read More

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Fetal Growth in Multiple Gestations: Evaluation and Management.

Obstet Gynecol Clin North Am 2021 Jun;48(2):401-417

Division of Maternal-Fetal Medicine, University of Colorado, Children's Hospital Colorado, Colorado Fetal Care Center, 12631 East 17th Avenue, Box B198-5, Aurora, CO 80045, USA.

Multifetal gestation pregnancies present a clinical challenge due to unique complications including growth issues, prematurity, maternal risk, and pathologic processes, such as selective intrauterine growth restriction (sIUGR), twin-to-twin transfusion syndrome (TTTS), and twin anemia-polycythemia sequence. If sIUGR is found, then management may involve some combination of increased surveillance, fetal procedures, and/or delivery. The combination of sIUGR with TTTS or other comorbidities increases the risk of pregnancy complications. Read More

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Pertussis immunization during pregnancy: assessment of the role of maternal antibodies on immune responses in term and preterm born infants.

Clin Infect Dis 2021 May 10. Epub 2021 May 10.

Centre for the Evaluation of Vaccination, Vaccine & Infectious Diseases Institute, University of Antwerp, Antwerp, Belgium.

Background: Limited data exist on the impact of maternal Tetanus, Diphtheria, acellular Pertussis (aP) (Tdap) vaccination for preterm born infants. We report its effect at birth and on antibody-mediated immune responses to a DTaP-IPV-HB-PRP~T vaccine in preterm compared to term infants.

Methods: Women delivering at term or prematurely were either vaccinated with a Tdap vaccine (Boostrix®, GSK) during pregnancy or not vaccinated in the last 5 years. Read More

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Associations of treated and untreated human papillomavirus infection with preterm delivery and neonatal mortality: A Swedish population-based study.

PLoS Med 2021 May 10;18(5):e1003641. Epub 2021 May 10.

Department of Obstetrics and Gynaecology, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Background: Treatment of cervical intraepithelial neoplasia (CIN) is associated with an increased risk of preterm delivery (PTD) although the exact pathomechanism is not yet understood. Women with untreated CIN also seem to have an increased risk of PTD. It is unclear whether this is attributable to human papillomavirus (HPV) infection or other factors. Read More

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Assessing the pregnancy protective impact of scheduled non-adherence of a novel progestin-only pill: a study protocol for a prospective, multi-centered, randomized, cross-over study.

JMIR Res Protoc 2021 May 5. Epub 2021 May 5.

Centre for Reproductive Health, University of Edinburgh, Edinburgh, GB.

Background: Oral contraceptives are the most widely used hormonal contraceptive methods in the United States. Progestin-only pills (POP) are commonly reserved for women with medical co-morbidities but in actuality, POPs can be safety used by anyone wanting to prevent pregnancy. This wide safety profile makes them an ideal candidate for being available over-the-counter without a prescription but adherence issues may be more common with over-the-counter use. Read More

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Risk of Pregnancy Termination and Congenital Anomalies After Domperidone Exposure: A Study in the EFEMERIS Database.

Drug Saf 2021 May 10. Epub 2021 May 10.

Réseau REGARDS, Laboratoire de Pharmacologie Médicale et Clinique (Medical and Clinical Pharmacology Laboratory), Centre Hospitalier Universitaire de Toulouse (Toulouse University Hospital Centre), Centre d'Epidémiologie et de Recherche en santé des POPulations (Center for Epidemiology and Research in POPulation health, CERPOP), INSERM UMR 1295, Equipe SPHERE: Study of Perinatal, paediatric and adolescent Health: Epidemiological Research and Evaluation, Faculté de Médecine de Toulouse (Toulouse Faculty of Medicine), 37 allées Jules Guesde, 31000, Toulouse, France.

Introduction: Domperidone is widely used during pregnancy, although the risks associated with pregnant women have not been adequately evaluated.

Objective: The objective of this study was to compare the rate of pregnancy outcomes and congenital anomalies between pregnant women exposed and unexposed to domperidone during pregnancy.

Methods: We conducted a retrospective cohort study comparing pregnant women exposed and unexposed to domperidone during pregnancy. Read More

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Cost-effectiveness of mifepristone and misoprostol versus misoprostol alone for the management of missed miscarriage: an economic evaluation based on the MifeMiso Trial.

BJOG 2021 May 10. Epub 2021 May 10.

NHS Greater Glasgow and Clyde, Glasgow, UK.

Objective: To assess the cost-effectiveness of mifepristone and misoprostol (MifeMiso) compared with misoprostol only for the medical management of a missed miscarriage.

Design: Within-trial economic evaluation and model-based analysis to set the findings in the context of the wider economic evidence for a range of comparators. Incremental costs and outcomes were calculated using non-parametric bootstrapping and reported using cost-effectiveness acceptability curves. Read More

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A review on the motivations, decision-making factors, attitudes and experiences of couples using pre-implantation genetic testing for inherited conditions.

Hum Reprod Update 2021 May 10. Epub 2021 May 10.

Division of Surgery and Cancer, Institute of Developmental Reproductive & Developmental Biology, Imperial College London, Chelsea and Westminster Hospital Campus, London, UK.

Background: In pre-implantation genetic testing (PGT), fertile couples undergo IVF with genetic testing of embryos to avoid conceptions with a genetic condition. There is an exponentially increasing uptake with over 600 applications listed by the Human Fertilisation and Embryology Authority in the UK. The psychological aspects of the decision-making process and the experience of PGT, however, are relatively underevaluated, with the potential to leave patients unsupported in their journeys. Read More

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Gestational and Breastfeeding Low-Protein Intake on Blood Pressure, Kidney Structure, and Renal Function in Male Rat Offspring in Adulthood.

Front Physiol 2021 22;12:658431. Epub 2021 Apr 22.

Fetal Programming and Hydroelectrolyte Metabolism Laboratory, Nucleus of Medicine and Experimental Surgery, Department of Internal Medicine, Faculty of Medical Sciences at State University of Campinas, Campinas, Brazil.

: Our previous studies demonstrated that maternal protein-restricted (low-protein, LP) 16-week-old offspring had pronounced nephron number reduction and arterial hypertension associated with an unchanged glomerular filtration rate (GFR). An enhanced gomerular area may be related to increased glomerular filtration and overflow, which accounts for glomerular filtration barrier breakdown and early glomerulosclerosis. The effect of protein restriction during gestational and breastfeeding periods is unknown. Read More

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Overweight and obesity at age 19 after pre-natal famine exposure.

Int J Obes (Lond) 2021 May 10. Epub 2021 May 10.

Netherlands Interdisciplinary Demographic Institute (NIDI-KNAW)/University of Groningen, The Hague/Groningen, Netherlands.

Background: Weight for height has been used in the past as an indicator of obesity to report that prenatal exposure to the Dutch famine of 1944-1945 determined subsequent obesity. Further evaluation is needed as unresolved questions remain about the possible impact of social class differences in fertility decline during the famine and because being overweight is now defined by a Body Mass Index (BMI: kg/m) from 25 to <30 and obesity by a BMI of 30 or more.

Methods: We studied heights and weights of 371,100 men in the Netherlands born between 1943 and 1947 and examined for military service at age 19. Read More

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Changes in anti-müllerian hormone after ultrasound guided aspiration and ethanol sclerotic therapy of ovarian cyst.

Taiwan J Obstet Gynecol 2021 May;60(3):509-512

Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, No 199 Dunhua N Rd, Songshan District, Taipei, 105, Taiwan. Electronic address:

Objective: To evaluate the effect of transvaginal ultrasound-guided aspiration and ethanol sclerotherapy on anti-müllerian hormone (AMH) in patients with ovarian endometriomas.

Setting: Teaching hospital affiliated with Chang Gung University, Taipei.

Material And Methods: We retrospectively reviewed 124 patients, with ovarian endometriomas who underwent transvaginal aspiration and sclerotherapy of endometrioma(s) at a tertiary medical center, Chang Gung Memorial Hospital, Taipei, Taiwan. Read More

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Signal Detection in EUROmediCAT: Identification and Evaluation of Medication-Congenital Anomaly Associations and Use of VigiBase as a Complementary Source of Reference.

Drug Saf 2021 May 9. Epub 2021 May 9.

Population Health Research Institute, St George's, University of London, London, UK.

Introduction: Knowledge on the safety of medication use during pregnancy is often sparse. Pregnant women are generally excluded from clinical trials, and there is a dependence on post-marketing surveillance to identify teratogenic medications.

Aims: This study aimed to identify signals of potentially teratogenic medications using EUROmediCAT registry data on medication exposure in pregnancies with a congenital anomaly, and to investigate the use of VigiBase reports of adverse events of medications in the evaluation of these signals. Read More

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Ultrasonographic evaluation of pelvic floor structure at antepartum and postpartum periods using three-dimensional transperineal ultrasound.

J Med Ultrason (2001) 2021 May 8. Epub 2021 May 8.

Department of Obstetrics and Gynecology, Saitama Medical University, 38 Morohongo Moroyama-machi, Iruma-gun, Saitama, 3500495, Japan.

Purpose: To examine the changes in the pelvic floor structure caused by pregnancy and delivery.

Methods: A total of 141 nulliparous women were examined with three-dimensional transperineal ultrasound (3D-TPU) at the 24th and 34th weeks of gestation, 5th day postpartum, and 1 month postpartum. Puborectalis muscle trauma was diagnosed and the area of levator hiatus (ALH) was measured. Read More

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A 45-year-old female patient with Sheehan's syndrome presenting with imminent adrenal crisis: a case report.

J Med Case Rep 2021 May 8;15(1):229. Epub 2021 May 8.

Department of Epidemiology and Biostatistics, School of Public Health, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.

Background: Sheehan's syndrome is hypopituitarism due to pituitary gland necrosis resulting from hemorrhagic shock during pregnancy. It is a rare complication with varied manifestations and a considerable delay in diagnosis.

Case Presentation: We describe the case of a 45-year-old Ethiopian woman who presented with generalized fatigue for 18 years which progressed to anorexia, nausea, vomiting, diarrhea, and abdominal pain of 6 years' duration, for which she was treated symptomatically throughout these years. Read More

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Fetomaternal Hemorrhage: Evaluation of Recurrence Within a Large Integrated Health Care System.

Am J Obstet Gynecol 2021 May 4. Epub 2021 May 4.

Kaiser Permanente Oakland Department of Pathology, 275 W MacArthur Boulevard Oakland, CA 94610.

Background: Fetomaternal hemorrhage is associated with severe fetal morbidity and mortality. The recurrence risk of fetomaternal hemorrhage is unknown.

Objective: We sought to establish the recurrence rate of fetomaternal hemorrhage in a large integrated healthcare system over a 10-year period. Read More

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Pediatric dental outcomes among children exposed to chemotherapy in utero.

Int J Paediatr Dent 2021 May 7. Epub 2021 May 7.

Department of Obstetrics and Gynecology, Cooper University Hospital, 1 Cooper Plaza, Camden, NJ, 08103, USA.

Aim: Our study prospectively evaluated dental development in children exposed to chemotherapy in utero compared to unexposed controls.

Design: Women who received chemotherapy while pregnant were enrolled in a research registry. After age two years, each child's dentist was asked to complete a questionnaire about dental abnormalities and malformations as well as for their unexposed siblings. Read More

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