59,481 results match your criteria Evaluation of Gestation

Out-of-hospital cardiac arrest in pregnant women: a 55-patient French cohort study.

Resuscitation 2022 Jun 24. Epub 2022 Jun 24.

The members of the study group are listed in the acknowledgment part at the end of the article.

Aim: To describe a cohort of pregnant women having suffered an out-of-hospital cardiac arrest (OHCA) and to compare them with nonpregnant women of childbearing age having suffered OHCA.

Methods: Study data were extracted from the French National OHCA Registry between 2011 and 2021. We compared patients in terms of characteristics, care and survival. Read More

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Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate.

Int J Toxicol 2022 Jun 27:10915818221111331. Epub 2022 Jun 27.

MediBeacon Inc., St. Louis, MO, USA.

The fluorescent tracer, MB-102, has been designed for the direct, real-time measurement of glomerular filtration rate. Previous studies, both and (rats, rabbits and dogs), were conducted to assess potential toxicity including single dose toxicity, mutation assay, chromosomal aberration assay, phototoxicity, local tolerance study, micronuclease assay, hERG channel changes, CNS and cardiovascular safety. The results of these studies led to a safety/toxicology profile for this agent deemed sufficient by the FDA to conduct Phase I and Phase II human clinical studies. Read More

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[Treatment of hypothyroidism in childbearing age].

Livia Barba

Recenti Prog Med 2022 Jun;113(6):3e-6e

Thyroid diseases play a crucial role in conditions of infertility and recurrent miscarriages. We here reported a case of a 34 years old woman, affected by autoimmune thyroiditis with subclinical hypothyroidism. The patient previously had a miscarriage and she was planning another pregnancy. Read More

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Evaluation of the relationship between serum TSH levels and pregnancy outcomes of IVF/ICSI patients in follicular phase long-acting long protocol.

Gynecol Endocrinol 2022 Jun 25:1-5. Epub 2022 Jun 25.

Reproductive Medical Centre, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China.

Objective: To investigate whether TSH levels are associated with the pregnancy outcomes of patients in the follicular phase long-acting long protocol of IVF/ICSI.

Methods: This was a single-central, retrospective study which was conducted in the Reproductive Medicine Center, Renmin Hospital of Wuhan University from February 2019 to April 2021. A total number of 773 patients underwent the follicular phase long-acting long protocol during in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) treatment were divided into Group A (0. Read More

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Evaluation of Antepartum Factors for Predicting the Risk of Emergency Cesarean Delivery in Pregnancies Complicated With Placenta Previa.

Ochsner J 2022 ;22(2):146-153

Department of Obstetrics and Gynecology, Health Sciences University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.

The optimal delivery timing for patients with placenta previa remains controversial in the literature. To reduce spontaneous vaginal bleeding rates, which occur increasingly with advancing gestational weeks, elective cesarean delivery is advocated between 36 and 37 weeks of gestation, but this clinical approach does not take into consideration numerous patient variables. Few papers identify the risk factors for emergency cesarean delivery in patients with placenta previa. Read More

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January 2022

Mesenteric venous thrombosis in a pregnant woman at first trimester gestation: a case report.

J Surg Case Rep 2022 Jun 21;2022(6):rjac294. Epub 2022 Jun 21.

General and Digestive Surgery Service, Hospital Nossa Senhora das Graças, Curitiba, Brazil.

Mesenteric vein thrombosis (MVT) in a pregnant patient is a rare condition that seems to be associated with the pregnancy pró-thrombotic state. This can lead to severe circumstances such as intestinal hemorrhagic ischemia, sepsis, abortion and death. Abdominal assessment is challenging due to the anatomical and physiological changes during pregnancy. Read More

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Umbilical Artery Systolic/Diastolic Ratio and Amniotic Fluid Index in Prediction of Adverse Perinatal Outcome in Term Pregnancies.

Int J Appl Basic Med Res 2022 Apr-Jun;12(2):76-81. Epub 2022 May 10.

Department of Obstetrics and Gynecology, Geetanjali Medical College, Udaipur, Rajasthan, India.

Background: Antenatal fetal surveillance is a field of increasing importance in modern obstetrics. It is based on fetal heart rate monitoring using nonstress test and contraction stress test, ultrasound biometry and amniotic fluid assessment, Doppler blood flow studies of fetal and uteroplacental circulation, and an evaluation of biophysical fetal parameters. The combination of these methods leads to improvements in fetal morbidity and mortality. Read More

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Cytotoxicity of Amphotericin B and AmBisome: and Evaluation Employing the Chick Embryo Model.

Front Pharmacol 2022 8;13:860598. Epub 2022 Jun 8.

Afzalipour School of Medicine and Pathology and Stem Cells Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Leishmaniasis has been identified as a significant disease in tropical and subtropical regions of the world, with Iran being one of the disease-endemic areas. Various treatments have been applied for this disease, and amphotericin B (Amp B) is the second line of treatment. Side effects of this drug have been reported in various organs. Read More

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Antenatal depression screening and psychosocial assessment in an Australian private hospital: An evaluation.

Aust N Z J Obstet Gynaecol 2022 Jun 27. Epub 2022 Jun 27.

Gidget Foundation Australia, North Sydney, New South Wales, Australia.

Background: Universal mental health screening and psychosocial assessment during pregnancy have been recommended as best practice, but uptake of universal programs in the private hospital system has been slow.

Aim: The aim of this study was to evaluate the Pre-admission Midwife Appointment Program (PMAP), an antenatal mental health screening program at the Mater Hospital, Sydney.

Materials And Methods: In this mixed-methods design study, PMAP interview data were collected for a consecutive series of 485 women who attended the PMAP during a 10-month period. Read More

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Evaluation of the predictive values of elevated serum L-homoarginine and dimethylarginines in preeclampsia.

Amino Acids 2022 Jun 26. Epub 2022 Jun 26.

Department of Laboratory Medicine, Wusong Branch, Zhongshan Hospital, Fudan University, Shanghai, 200940, China.

L-homoarginine (hARG) is involved in nitric oxide biosynthesis, but its role and concentration in preeclampsia (PE) have not been fully revealed. The purpose of this study was to develop and validate a feasible clinical assay to quantify serum hARG, arginine (ARG), asymmetric (ADMA) and symmetric dimethylarginines (SDMA) levels by LC-MS/MS and investigate their differences at different stages of pregnancy with or without preeclampsia. Serum samples were collected from 84 pregnant women without complications (controls), 84 with mild preeclampsia (MPE), and 81 with severe preeclampsia (SPE) at various gestation stages (before the 20th week, during the 20th-28th week or after the 28th week of gestation). Read More

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Expectant versus medical management for retained products of conception after medical termination of pregnancy: A randomized controlled study.

Am J Obstet Gynecol 2022 Jun 22. Epub 2022 Jun 22.

Department of Obstetrics and Gynecology, Lis Hospital for Women's Health, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Despite the rise of medical treatments for the termination of pregnancy, to-date no prospective trial has evaluated the efficacy of misoprostol in treating retained products of conception after induced termination of pregnancy.

Objective: To compare medical management with misoprostol with expectant management for retained products of conception after first trimester medical termination of pregnancy.

Study Design: An open-label randomized controlled trial conducted at a university-affiliated tertiary medical center. Read More

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Evaluation of the feasibility of the FAST-M maternal sepsis intervention in Pakistan: a protocol.

Pilot Feasibility Stud 2022 Jun 24;8(1):130. Epub 2022 Jun 24.

Institute of Life Course and Medical Sciences, University of Liverpool, William Henry Duncan Building, Liverpool, L7 8TX, UK.

Background: Maternal sepsis is a life-threatening condition, defined by organ dysfunction caused by infection during pregnancy, childbirth, and the postpartum period. It is estimated to account for between one-tenth and half (4.7% to 13. Read More

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Mixed methods evaluation of simulation-based training for postpartum hemorrhage management in Guatemala.

BMC Pregnancy Childbirth 2022 Jun 24;22(1):513. Epub 2022 Jun 24.

Department of Obstetrics & Gynecology, Division of Maternal-Fetal Medicine, Stanford University School of Medicine, Stanford, USA.

Background: To assess if simulation-based training (SBT) of B-Lynch suture and uterine balloon tamponade (UBT) for the management of postpartum hemorrhage (PPH) impacted provider attitudes, practice patterns, and patient management in Guatemala, using a mixed-methods approach.

Methods: We conducted an in-country SBT course on the management of PPH in a governmental teaching hospital in Guatemala City, Guatemala. Participants were OB/GYN providers (n = 39) who had or had not received SBT before. Read More

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Impact of vaccination during pregnancy on infants' immune responses to vaccinations- definitions and statistical approaches.

Vaccine 2022 Jun 21. Epub 2022 Jun 21.

Department of Pediatrics, Division of Infectious Diseases, University of British Columbia, Vancouver, British Columbia, Canada; Vaccine Evaluation Center, British Columbia Children's Hospital Research Institute, Vancouver, British Columbia, Canada. Electronic address:

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Development of the Sepsis-Associated Adverse Outcomes in Pregnancy Score.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Obstetrics & Gynecology, Department of Obstetrics, Gynecology, and Reproductive Sciences, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, United States.

Objective: To develop and evaluate a scoring system-called Sepsis-Associated Adverse Outcomes in Pregnancy (SAAP) Score-to identify individuals with maternal infection that have composite maternal adverse outcomes (CMAO).

Study Design: Using ICD codes, we identified pregnant and postpartum (up to 6 weeks after birth) individuals admitted at our center with a primary diagnosis of infection. The primary outcome was CMAO, which included any of the following: maternal intensive care unit admission, surgical intervention, vasopressor use, acute respiratory distress syndrome, pulmonary edema, mechanical ventilation, high flow nasal cannula, disseminated intravascular coagulation, dialysis, organ failure, venous thromboembolism, or maternal death. Read More

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Being a mother under the COVID-19 pandemic lockdown: Evaluation of perinatal anxiety, prenatal attachment, and maternal-infant attachment.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Obstetrics and Gynecology, TC Saglik Bakanligi Izmir Il Saglik Mudurlugu Izmir Saglik Bilimleri Universitesi Tepecik Egitim ve Arastirma Hastanesi, Izmir, Turkey.

Objectives: The COVID-19 pandemic has caused both physical and emotional stress throughout the population due to its worldwide impact. The unknowns about the disease, the social isolation, and pregnant women's concerns regarding exposure to the COVID-19, inaccessibility to necessary care, and the possibility of harm to their fetus, may cause increased psychological distress during the perinatal period. We aimed to evaluate the association between perinatal anxiety, prenatal attachment, and maternal-infant attachment status among women with those who delivered their child in a tertiary care center with rigid hospital restrictions. Read More

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Do sclero-embolization procedures have advantages over surgical ligature in treating varicocele in children, adolescents and adults? Results from a systematic review and meta-analysis.

Andrologia 2022 Jun 24:e14510. Epub 2022 Jun 24.

Urology Unit, Azienda Ospedaliero-Universitaria Ospedali Riuniti di Ancona, Polytechnic University of the Marche Region, Ancona, Italy.

We aimed to systematically review complications, and recurrence rate of varicocele treatment by comparing the surgical ligature versus sclero-embolization techniques in children, adolescents and adults. The secondary outcomes were the evaluation of semen parameters and spontaneous pregnancy rate in adults. The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework. Read More

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Evaluation of placental oxygenation in fetal growth restriction using blood oxygen level-dependent magnetic resonance imaging.

Placenta 2022 Jun 18;126:40-45. Epub 2022 Jun 18.

Department of Obstetrics and Gynecology, Mie University Faculty Medicine, Mie, Japan.

Introduction: Abnormalities in placental function can lead to fetal growth restriction (FGR), but there is no consensus on their evaluation. Using blood oxygen level-dependent magnetic resonance imaging (BOLD MRI), we compared placental oxygenation between FGR cases and previously reported normal pregnancies.

Methods: Eight singleton pregnant women (>32 weeks of gestation) diagnosed with fetal growth failure during pregnancy were recruited. Read More

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Advances in the ultrasound diagnosis in equine reproductive medicine: new approaches.

Reprod Domest Anim 2022 Jun 24. Epub 2022 Jun 24.

Laboratory of Equine Reproduction and Equine Spermatology, Veterinary Teaching Hospital, University of Extremadura, Cáceres, Spain.

Ultrasound technology has led to new lines of research in equine reproduction, and it has helped to greatly improve clinical diagnosis and reproductive outcomes in equine practice. This review aims to discuss the potential clinical uses and new approaches of ultrasonography in equine reproduction. Doppler modalities are usually used to evaluate the vascularization of the follicles, corpus luteum (CL), and the uterus in the mare for diagnostic purposes. Read More

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Evaluation of the tolerability of monoclonal antibody therapy for pregnant patients with COVID-19.

J Obstet Gynaecol Res 2022 Jun 24. Epub 2022 Jun 24.

Department of Obstetrics and Gynecology, Mie University Faculty Medicine, Mie, Japan.

Aim: To evaluate the tolerability of casirivimab and imdevimab (CAS/IMB) therapy in pregnant women with COVID-19 in Japan and its impact on the neonate and process of delivery.

Methods: Eight cases of pregnancy complicated by COVID-19 and requiring hospitalization during the delta variant epidemic were included. Gestational age, initial symptoms, pregnancy complications and outcome, severity of illness, blood test findings at the time of treatment initiation and on days 3-5 after administration, body temperature at administration, and 8, 24, and 48 h post-administration, delivery outcome, and neonatal findings were recorded. Read More

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Hepatitis C is associated with more adverse pregnancy outcomes than hepatitis B: A 7-year national inpatient sample study.

Hepatol Commun 2022 Jun 24. Epub 2022 Jun 24.

Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Prior international studies have shown mixed results regarding the association of hepatitis B and hepatitis C with adverse pregnancy outcomes. We performed an updated evaluation of the prevalence of associated adverse pregnancy outcomes and evaluated trends over time of diagnosis of chronic hepatitis B (HBV) and chronic hepatitis C (HCV) in pregnant women in a national database. All pregnant women with HBV and HCV were identified from the National Inpatient Sample database 2012 to 2018. Read More

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Cost-effectiveness of antenatal corticosteroids and tocolytic agents in the management of preterm birth: A systematic review.

EClinicalMedicine 2022 Jul 3;49:101496. Epub 2022 Jun 3.

Maternal, Child and Adolescent Health Program, Burnet Institute, Melbourne, Australia.

Background: Preterm birth is a leading cause of neonatal mortality and morbidity, and imposes high health and societal costs. Antenatal corticosteroids (ACS) to accelerate fetal lung maturation are commonly used in conjunction with tocolytics for arresting preterm labour in women at risk of imminent preterm birth.

Methods: We conducted a systematic review on the cost-effectiveness of ACS and/or tocolytics as part of preterm birth management. Read More

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Three-Dimensional (3D) Imaging Technology to Monitor Growth and Development of Holstein Heifers and Estimate Body Weight, a Preliminary Study.

Sensors (Basel) 2022 Jun 19;22(12). Epub 2022 Jun 19.

PEGASE, INRAE, Institut Agro, 35590 Saint-Gilles, France.

The choice of rearing strategy for dairy cows can have an effect on production yield, at least during the first lactation. For this reason, it is important to closely monitor the growth and development of young heifers. Unfortunately, current methods for evaluation can be costly, time-consuming, and dangerous because of the need to physically manipulate animals, and as a result, this type of monitoring is seldom performed on farms. Read More

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Pattern of Antibiotic Use in the Perinatal Period in a Public University Hospital in Romania.

Medicina (Kaunas) 2022 Jun 7;58(6). Epub 2022 Jun 7.

Psycho-Neurosciences and Recovery Department, Faculty of Medicine and Pharmacy, University of Oradea, 1 University Street, 410087 Oradea, Romania.

: Antibiotics are the most frequently prescribed drugs in hospitals and their prescription is increased during pregnancy and labor. There are limited data about this issue, and the safe use of antibiotics in pregnancy and antibiotic resistance remains a concern. The aim of the study is to evaluate the use of antibiotics among pregnant women attending hospital for five years. Read More

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The Value of Fetal Head Station as a Delivery Mode Predictor in Primiparous Women at Term before the Onset of Labor.

J Clin Med 2022 Jun 8;11(12). Epub 2022 Jun 8.

Department of Obstetrics and Gynecology, University Emergency County Hospital Craiova, 200642 Craiova, Romania.

Objective: Our objective was to demonstrate the role of the clinical determination of fetal head station (FHS) at term to predict the delivery mode in primiparous women before the onset of labor.

Methods: This prospective study included unselected primiparous women at term who presented at our tertiary maternity. We excluded multiparous patients, pregnancies with a planned Cesarean section, non-cephalic presentations, and multiple pregnancies. Read More

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Developmental Exposure to Endocrine Disrupter DDT Interferes with Age-Related Involution of Thymus.

Int J Mol Sci 2022 Jun 15;23(12). Epub 2022 Jun 15.

Department of Histology, Cytology, and Embryology, Federal State Funded Educational Institution of Higher Education, I.M. Sechenov First Moscow State Medical University, 119435 Moscow, Russia.

The impact of endocrine-disrupting chemicals on the development and involution of the immune system is a possible reason for the increased incidence of disorders associated with inappropriate immune function. The thymus is a lymphoid and also an endocrine organ, and, accordingly, its development and functioning may be impaired by endocrine disruptors. The aim was to evaluate age-related thymus involution in mature rats exposed to the endocrine disruptor DDT during prenatal and postnatal ontogeny. Read More

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Neurodevelopment in Normocephalic Children Exposed to Zika Virus in Utero with No Observable Defects at Birth: A Systematic Review with Meta-Analysis.

Int J Environ Res Public Health 2022 Jun 14;19(12). Epub 2022 Jun 14.

ISGlobal, Hospital Clínic-Universitat de Barcelona, 132 Rosselló Street, 08036 Barcelona, Spain.

Zika virus (ZIKV) infection during pregnancy is a cause of pregnancy loss and multiple clinical and neurological anomalies in children. This systematic review aimed to assess the effect of ZIKV exposure in utero on the long-term neurodevelopment of normocephalic children born to women with ZIKV infection in pregnancy. This review was conducted according to the PRISMA guidelines for systematic reviews and meta-analyses. Read More

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Evaluation of Infant Injury Prevention Education Provided during Antenatal Classes after Two Years: A Pilot Prospective Cohort Study.

Int J Environ Res Public Health 2022 Jun 11;19(12). Epub 2022 Jun 11.

Department of Gerontological home Care and Long-Term Care Nursing/Palliative Care Nursing, Graduate School of Medicine, The University of Tokyo, Tokyo 113-0033, Japan.

This study examined the long-term effects of an infant injury prevention program implemented during an antenatal class of 131 mothers. Questionnaires were completed 2 years postpartum to assess the incidence of injury (medically attended or home-care), mothers' perception of injury prevention, implementation of safety practices, and active attitudes toward injury prevention. Responses were obtained from 68 (51. Read More

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Risk Measurement of Perinatal and Neonatal Morbidity Characteristics and Applicability of GAIA Case Definitions: Results and Lessons Learnt of a Hospital-Based Prospective Cohort Study in the Valencia Region (2019-2020).

Int J Environ Res Public Health 2022 Jun 10;19(12). Epub 2022 Jun 10.

Vaccines Research Department, Fundación Para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (Fisabio), Av. de Catalunya, 21, 46020 Valencia, Spain.

Post-marketing safety surveillance of new vaccines aimed to be administered during pregnancy is crucial to orchestrate efficient adverse events evaluation. This is of special relevance in the current landscape of new vaccines being introduced in the pregnant women population, and particularly due to the recent administration of COVID-19 vaccines in pregnant women. This multi-center prospective cohort study, nested within the WHO-Global Vaccine Safety-MCC study, involved two hospitals in the Valencia region. Read More

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Evaluation of a Maternal Plasma RNA Panel Predicting Spontaneous Preterm Birth and Its Expansion to the Prediction of Preeclampsia.

Diagnostics (Basel) 2022 May 27;12(6). Epub 2022 May 27.

Department of Obstetrics and Gynecology, University of Illinois-Chicago, Chicago, IL 60612, USA.

Preterm birth is the principal contributor to neonatal death and morbidity worldwide. We previously described a plasma cell-free RNA panel that between 16 and 20 weeks of pregnancy had potential to predict spontaneous preterm birth (sPTB) ≤ 32 weeks caused by preterm labor (PTL) or preterm premature rupture of membranes (PPROM). The present study had three objectives: estimate the RNA panel prognostic accuracy for PTL/PPROM ≤ 32 weeks in a larger series; improve accuracy by adding clinical characteristics to the predictive model; and examine the association of the RNA panel with preeclampsia. Read More

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