8,124 results match your criteria European Journal of Radiology[Journal]


Corrigendum to "MR features based on LI-RADS identify cytokeratin 19 status of hepatocellular carcinomas" [Eur. J. Radiol. 113 (2019) 7-14].

Eur J Radiol 2019 May 24;114:193. Epub 2019 Mar 24.

Department of Radiology, Zhongshan Hospital, Fudan University, and Shanghai Medical Imaging Institute, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2019.03.013DOI Listing

The prognostic significance of intratumoral heterogeneity of 18F-FDG uptake in patients with oral cavity squamous cell carcinoma.

Eur J Radiol 2019 May 11;114:99-104. Epub 2019 Mar 11.

Department of Oral and Maxillofacial Surgery, Ogaki Municipal Hospital, Ogaki, Japan.

Purpose: This study aimed to evaluate the prognostic significance of two major indices of intratumoral heterogeneity of 18F-fluorodeoxyglucose uptake by positron emission tomography (PET)/computed tomography (CT), namely heterogeneity index (HI) and heterogeneity factor (HF), in patients with oral squamous cell carcinoma.

Methods: We performed a retrospective analysis of 62 patients who underwent resective surgery. HI, HF, maximum standardized uptake value (SUV), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) were obtained from pretreatment PET. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.004DOI Listing
May 2019
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Which clinical and radiological characteristics can predict clinically significant prostate cancer in PI-RADS 3 lesions? A retrospective study in a high-volume academic center.

Eur J Radiol 2019 May 25;114:92-98. Epub 2019 Feb 25.

Department of Radiology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium. Electronic address:

Objective: To investigate which clinical and radiological characteristics can predict clinically significant prostate cancer (csPCa) in PI-RADS 3 lesions. To investigate which clinical and radiological characteristics influence the clinician to biopsy a PI-RADS 3 lesion.

Materials And Methods: mpMRI PI-RADS 3 lesions scored by 1 out of 3 highly specialized radiologists in a single high-volume center during the period March 2015 to August 2017 were investigated. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.031DOI Listing
May 2019
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Percutaneous CT guided bone biopsy for suspected osteomyelitis: Diagnostic yield and impact on patient's treatment change and recovery.

Eur J Radiol 2019 May 8;114:85-91. Epub 2019 Feb 8.

Radiology, UT Southwestern Medical Center, Dallas, TX, USA; Orthopedics, UT Southwestern Medical Center, Dallas, TX, USA.

Aim: To evaluate the utility of percutaneous CT guided bone biopsy (PCBB) for suspected osteomyelitis (OM) and its eventual impact on patient management and recovery.

Material And Methods: Patients who received a PCBB for suspected osteomyelitis from years 2012-2018. Patient demographics, lesion location, ulcer grade, signs of toxemia, serology, wound and blood cultures, bone biopsy and cross-sectional imaging results were recorded. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.032DOI Listing

Comparison between subtalar joint quantitative kinematic 4-D CT parameters in healthy volunteers and patients with joint stiffness or chronic ankle instability: A preliminary study.

Eur J Radiol 2019 May 5;114:76-84. Epub 2019 Mar 5.

Service D'imagerie Guilloz, Hôpital Central, CHU Nancy, F-54000, France.

Objective: to compare quantitative kinematic 4-D CT parameters between healthy volunteers and pathologic patients (joint stiffness or chronic ankle instability).

Methods: Thirteen healthy volunteers without previous ankle trauma, 18 patients with clinical subtalar joint stiffness and 10 patients with chronic ankle instability diagnosed based on clinical and imaging findings were prospectively evaluated with 4-D CT. This study was approved by the local ethics committee and all patients signed an informed consent. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.001DOI Listing

Functional connectivity disruption of the substantia nigra associated with cognitive impairment in acute mild traumatic brain injury.

Eur J Radiol 2019 May 8;114:69-75. Epub 2019 Mar 8.

Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China. Electronic address:

Purpose: Mild traumatic brain injury is known to have frequent cognitive impairment. Accumulating evidence is pointing to the malfunctioning of the substantia nigra (SN) as an important factor for head trauma. However, it remains unknown whether changes in the SN-based resting state functional connectivity following mTBI at acute stage and its relationship with cognitive function. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.002DOI Listing

Ultra-low dose chest computed tomography: Effect of iterative reconstruction levels on image quality.

Eur J Radiol 2019 May 18;114:62-68. Epub 2019 Feb 18.

Department of Diagnostic Physics, Oslo University Hospital, Oslo, Norway; The Department of Physics, University of Oslo, Oslo, Norway.

Purpose: To optimize image quality and radiation dose of chest CT with respect to various iterative reconstruction levels, detector collimations and body sizes.

Method: A Kyoto Kagaku Lungman with and without extensions was scanned using fixed ultra-low doses of 0.25, 0. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.021DOI Listing

Agreement of 2D transthoracic echocardiography with cardiovascular magnetic resonance imaging after ST-elevation myocardial infarction.

Eur J Radiol 2019 May 28;114:6-13. Epub 2019 Feb 28.

University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, PO box 30.001, 9700 RB, the Netherlands; University of Groningen, University Medical Center Groningen, Center for Medical Imaging, Groningen, PO box 30.001, 9700 RB, the Netherlands. Electronic address:

Background: This study was designed to investigate the agreement of 2D transthoracic echocardiography (2D TTE) with cardiovascular magnetic resonance imaging (CMR) in a contemporary population of ST-elevation myocardial infarction (STEMI) patients.

Methods: In this subanalysis of the GIPS-III trial, a randomized controlled trial investigating the administration of metformin in STEMI patients to prevent reperfusion injury, we studied 259 patients who underwent same-day CMR and 2D TTE assessments four months after hospitalization for a first STEMI. Bland-Altman analyses were performed to assess agreement between LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), LV ejection fraction (LVEF), and LV mass measurements. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.039DOI Listing

Background parenchymal enhancement assessment: Inter- and intra-rater reliability across breast MRI sequences.

Eur J Radiol 2019 May 27;114:57-61. Epub 2019 Feb 27.

Department of Diagnostic Imaging and Radiotherapy, Radiology Institute, University of Turin, A. O. U. Città della Salute e della Scienza di Torino - Presidio Ospedaliero Molinette, Via Genova 3, 10126, Turin, Italy.

Objective: To evaluate inter- and intra-rater reliability of background parenchymal enhancement (BPE) assessment across breast MRI sequences.

Materials And Methods: Institutional review board approval was obtained and the requirement for consent was waived. Three radiologists qualitatively categorized BPE on 150 breast MRI using a four-point scale (minimal, mild, moderate or marked) according to BI-RADS category system. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.036DOI Listing

Does higher field strength translate into better diagnostic accuracy? A prospective comparison of breast MRI at 3 and 1.5 Tesla.

Eur J Radiol 2019 May 28;114:51-56. Epub 2019 Feb 28.

Department of Biomedical Imaging and Image-Guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna, Waehringer-Guertel 18-20, Vienna, Austria. Electronic address:

Objective: We performed a prospective monocentric study to inter-individually compare the diagnostic accuracy of breast MRI at 1.5 T and 3 T.

Methods: During a consecutive period of 12 months all 982 patients receiving breast MRI according to standard indications (problem solving, preoperative staging) were randomized to one 3 T or 1. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.033DOI Listing

Qualitative versus quantitative lumbar spinal stenosis grading by machine learning supported texture analysis-Experience from the LSOS study cohort.

Eur J Radiol 2019 May 19;114:45-50. Epub 2019 Feb 19.

Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Zurich, Switzerland.

Purpose: To investigate and compare the reproducibility and accuracy of qualitative ratings and quantitative texture analysis (TA) in detection and grading of lumbar spinal stenosis (LSS) in magnetic resonance imaging (MR) scans of the lumbar spine.

Materials And Methods: From a nationwide multicenter and multidisciplinary lumbar stenosis outcome study (LSOS) register 82 patients, undergoing MR scans of the lumbar spine due to clinical indication of spinal claudication, with a single level central or lateral severe LSS were included. In total 343 transaxial T2-weighted images of the lumbar spine were included from one to five levels (L1 to S1) per patient. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X193007
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http://dx.doi.org/10.1016/j.ejrad.2019.02.023DOI Listing
May 2019
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Using biparametric MRI radiomics signature to differentiate between benign and malignant prostate lesions.

Eur J Radiol 2019 May 25;114:38-44. Epub 2019 Feb 25.

Imaging Center, Wuxi People's Hospital, Nanjing Medical University, No. 299, Qingyang Road, Liangxi District, Wuxi, Jiangsu Province, 214023, China. Electronic address:

Purpose: To investigate the efficiency of radiomics signature in discriminating between benign and malignant prostate lesions with similar biparametric magnetic resonance imaging (bp-MRI) findings.

Experimental Design: Our study consisted of 331 patients underwent bp-MRI before pathological examination from January 2013 to November 2016. Radiomics features were extracted from peripheral zone (PZ), transition zone (TZ), and lesion areas segmented on images obtained by T2-weighted imaging (T2WI), diffusion-weighted imaging (DWI), and its derivative apparent-diffusion coefficient (ADC) imaging. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.032DOI Listing
May 2019
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Interventional oncology treatments for unresectable early stage HCC in patients with a high risk for intraprocedural bleeding: Is a single-step combined therapy safe and feasible?

Eur J Radiol 2019 May 23;114:32-37. Epub 2019 Feb 23.

Fondazione Fondazione Policlinico Universitario A. Gemelli IRCCS, UOC di Radiologia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Roma, Italy; Università Cattolica del Sacro Cuore, Istituto di Radiologia, Roma, Italy.

Purpose: This study was designed to assess the feasibility and safety of a single-step combined therapy using radiofrequency ablation and transarterial chemoembolization (RFA + TACE) in patients with hepatocellular carcinoma (HCC) and uncontrolled coagulopathy. The study also aimed to compare the effectiveness of this approach with TACE alone, performed in a control group.

Material And Methods: One hundred and forty-three consecutive cirrhotic patients having a single HCC < 8 cm were enrolled in this observational prospective single-center study from January 2010 to June 2017 and were divided, according to coagulation tests, into three groups (A: low risk; B: intermediate risk and C: high risk of bleeding). Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.030DOI Listing

Can whole-tumor apparent diffusion coefficient histogram analysis be helpful to evaluate breast phyllode tumor grades?

Eur J Radiol 2019 May 27;114:25-31. Epub 2019 Feb 27.

Department of Radiology, Guangdong Academy of Medical Sciences/Guangdong General Hospital, Guangzhou, 510180, China. Electronic address:

Purpose: To investigate whether whole-tumor apparent diffusion coefficient (ADC) histogram analysis could be helpful to evaluate breast phyllode tumor (PT) grades.

Materials And Methods: This institutional review board-approved retrospective study included 56 PTs (23 benign lesions, 22 borderline lesions, and 11 malignant lesions) from August 2011 to November 2017. MRI was performed using a 1. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.035DOI Listing
May 2019
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The accuracy of incremental pre-operative breast MRI findings - Concordance with histopathology in the Swedish randomized multicenter POMB trial.

Eur J Radiol 2019 May 14;114:185-191. Epub 2019 Mar 14.

Region Västmanland-Uppsala University, Center for Clinical Research, Hospital of Västmanland Västerås, 721 89 Västerås, Sweden; Department of Surgery, Hospital of Västmanland, 721 89 Västerås, Sweden.

Purpose: The Pre-Operative MRI of the Breast (POMB) trial was a randomized, prospective, multicenter trial evaluating the impact of pre-operative breast MRI on treatment regimens and short-term surgical outcomes in women up to 56 years of age with breast cancer. The purpose of this study was to evaluate the performance of pre-operative breast MRI in the POMB trial with respect to incremental MRI findings - over conventional breast imaging methods - and their concordance with histopathology.

Patients And Methods: Two-hundred and ten patients (n = 210) participating in the POMB trial underwent pre-operative breast MRI at two Swedish breast units. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.005DOI Listing

Prediction of molecular subtypes of breast cancer using BI-RADS features based on a "white box" machine learning approach in a multi-modal imaging setting.

Eur J Radiol 2019 May 21;114:175-184. Epub 2019 Mar 21.

Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands. Electronic address:

Purpose: To develop and validate an interpretable and repeatable machine learning model approach to predict molecular subtypes of breast cancer from clinical metainformation together with mammography and MRI images.

Methods: We retrospectively assessed 363 breast cancer cases (Luminal A 151, Luminal B 96, HER2 76, and BLBC 40). Eighty-two features defined in the BI-RADS lexicon were visually described. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.015DOI Listing

Imaging features of triple-negative breast cancers according to androgen receptor status.

Eur J Radiol 2019 May 21;114:167-174. Epub 2019 Mar 21.

Department of Diagnostic Radiology, Unit 1350, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX, 77030, USA. Electronic address:

Objective: Different molecular subtypes of triple-negative breast cancer (TNBC) have previously been identified through analysis of gene expression profiles. The luminal androgen receptor (LAR) subtype has been shown to have a lower rate of pathologic complete response to neoadjuvant chemotherapy than other TNBC subtypes. The purpose of this study was to determine if the imaging features of TNBCs differ by AR (androgen receptor) status, which is a surrogate immunohistochemical (IHC) marker for the chemoresistant LAR subtype of TNBC. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.017DOI Listing
May 2019
2.369 Impact Factor

Feasibility of Dixon magnetic resonance imaging to quantify effects of physical training on muscle composition-A pilot study in young and healthy men.

Eur J Radiol 2019 May 26;114:160-166. Epub 2019 Mar 26.

Institute of Medical Physics, Friedrich-Alexander University Erlangen-Nuremberg (FAU), Henkestr. 91, 91052 Erlangen, Germany; Department of Medicine 3, Friedrich-Alexander University Erlangen-Nuremberg (FAU) and University Hospital Erlangen, Ulmenweg 18, Erlangen, Germany. Electronic address:

Changes in muscle-fat-composition affect physical performance and muscular function, like strength and power. The purpose of the present study was to investigate whether changes in soft tissue composition of the thigh and changes in muscle size and composition resulting from physical training were detectable with Dixon magnetic resonance imaging (MRI). A young and healthy subject population (n = 21, 29 ± 5 years) was split into a strength training (G_t, 11 subjects) and a control group (G_c, 10 subjects). Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.019DOI Listing

Noninvasive assessment of H3 K27M mutational status in diffuse midline gliomas by using apparent diffusion coefficient measurements.

Eur J Radiol 2019 May 14;114:152-159. Epub 2019 Mar 14.

Department of Medical Imaging, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, PR China. Electronic address:

Purpose: H3 K27M-mutant diffuse midline gliomas are associated with worse prognosis than H3 K27M wild-type gliomas. In the present study, we sought to evaluate the conventional magnetic resonance imaging (cMRI) of H3 K27M-mutant glioma and examine whether diffusion-weighted imaging (DWI) derived apparent diffusion coefficient (ADC) could noninvasively predict H3 K27M mutational status in brain diffuse midline gliomas.

Materials And Methods: The institutional review board approved this study and waived the requirement for informed consent. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.006DOI Listing

MRI with diffusion-weighted imaging to predict feasibility of complete cytoreduction with the peritoneal cancer index (PCI) in advanced stage ovarian cancer patients.

Eur J Radiol 2019 May 15;114:146-151. Epub 2019 Mar 15.

Department of Radiology, The Netherlands Cancer Institute, PO Box 900203, 1006 BE, Amsterdam, the Netherlands. Electronic address:

Objectives: To determine the diagnostic performance of MRI with diffusion-weighted imaging (DW-MRI) in assessing the peritoneal tumor load and predicting whether a complete cytoreduction can be achieved in patients with epithelial ovarian cancer (EOC).

Methods: For this observational prospective study, 25 patients with epithelial ovarian cancer scheduled for cytoreductive surgery were included. Patients underwent a 3 T DW-MRI scan prior to surgery. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.007DOI Listing

The present and future of deep learning in radiology.

Eur J Radiol 2019 May 2;114:14-24. Epub 2019 Mar 2.

Stroke Monitoring and Diagnostic Division, AtheroPoint™, Roseville, CA, USA. Electronic address:

The advent of Deep Learning (DL) is poised to dramatically change the delivery of healthcare in the near future. Not only has DL profoundly affected the healthcare industry it has also influenced global businesses. Within a span of very few years, advances such as self-driving cars, robots performing jobs that are hazardous to human, and chat bots talking with human operators have proved that DL has already made large impact on our lives. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X193009
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http://dx.doi.org/10.1016/j.ejrad.2019.02.038DOI Listing
May 2019
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The feasibility in estimating pulmonary vascular resistance by cardiovascular magnetic resonance in pulmonary hypertension: A systematic review and meta-analysis.

Eur J Radiol 2019 May 20;114:137-145. Epub 2019 Mar 20.

Department of Radiology, The Yongchuan Affiliated Hospital, Chongqing Medical University, Yongchuan District, Chongqing, PR China. Electronic address:

Purpose: Cardiac magnetic resonance (CMR) is a substitute technique for noninvasively assessing pulmonary hemodynamics. Some preliminary studies have shown that CMR has the potential to quantify pulmonary vascular resistance (PVR). However, the evaluative value has not been well established. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.014DOI Listing

The problematic lung nodule.

Eur J Radiol 2019 May 21;114:136. Epub 2019 Mar 21.

Saint Louis University School of Medicine, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ejrad.2019.03.011DOI Listing

Preoperative prediction of pelvic lymph nodes metastasis in early-stage cervical cancer using radiomics nomogram developed based on T2-weighted MRI and diffusion-weighted imaging.

Eur J Radiol 2019 May 20;114:128-135. Epub 2019 Mar 20.

Department of Medical Imaging, First Affiliated Hospital of Xi'an Jiaotong University, No.277, West Yanta Road, Xi'an, 710061, Shaanxi, People's Republic of China. Electronic address:

Objective: To explore an MRI-based radiomics nomogram for preoperatively predicting of pelvic lymph node (PLN) metastasis in patients with early-stage cervical cancer (ECC).

Methods: Ninety-six patients with ECC were enrolled in this study. All patients underwent T2WI and DWI scans before radical hysterectomy with PLN dissection surgery. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X193000
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http://dx.doi.org/10.1016/j.ejrad.2019.01.003DOI Listing
May 2019
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Modelling MR and clinical features in grade II/III astrocytomas to predict IDH mutation status.

Eur J Radiol 2019 May 14;114:120-127. Epub 2019 Mar 14.

Department of Brain Repair and Rehabilitation, UCL Institute of Neurology, London, UK; National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Background And Purpose: There is increasing evidence that many IDH wildtype (IDHwt) astrocytomas have a poor prognosis and although MR features have been identified, there remains diagnostic uncertainty in the clinic. We have therefore conducted a comprehensive analysis of conventional MR features of IDHwt astrocytomas and performed a Bayesian logistic regression model to identify critical radiological and basic clinical features that can predict IDH mutation status.

Materials And Methods: 146 patients comprising 52 IDHwt astrocytomas (19 WHO Grade II diffuse astrocytomas (A II) and 33 WHO Grade III anaplastic astrocytomas (A III)), 68 IDHmut astrocytomas (53 A II and 15 A III) and 26 GBM were studied. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X193009
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http://dx.doi.org/10.1016/j.ejrad.2019.03.003DOI Listing
May 2019
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Comparison of diagnostic performance between two prostate imaging reporting and data system versions: A systematic review.

Eur J Radiol 2019 May 20;114:111-119. Epub 2019 Mar 20.

Department of Medical Imaging, Jiangsu Vocational College of Medicine, Yancheng City, China. Electronic address:

Objective: To compare the diagnostic performance between Prostate Imaging Reporting and Data System version 1(PI-RADS v1) and PI-RADS v2 for detection of prostate cancer (PCa).

Methods: A systematic literature search was performed from inception to September 31, 2018, in following databases MEDLINE, EMBASE, Cochrane Library, Google Scholar, in addition to Chinese National Knowledge Infrastructure (CNKI) and Wanfang Data database. Sensitivity and specificity of individual studies along with summary estimates were calculated and presented in forest plots. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0720048X193011
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http://dx.doi.org/10.1016/j.ejrad.2019.03.016DOI Listing
May 2019
2 Reads

The usefulness of the oblique coronal plane of three-dimensional isotropic T2-weighted fast spin-echo (VISTA) knee MRI in the evaluation of posterior cruciate ligament reconstruction with allograft: Comparison with the oblique coronal plane of two-dimensional fast spin-echo T2-weighted sequences.

Eur J Radiol 2019 May 16;114:105-110. Epub 2019 Mar 16.

Department of Radiology, Myongji hospital, Republic of Korea.

Purpose: We compared two imaging techniques to assess whether 3D VISTA imaging could replace 2D FSE in diagnosing PCL reconstruction complications.

Materials And Methods: This retrospective study included 40 patients who underwent surgery of PCL reconstruction and follow-up knee MRI (3D VISTA and 2D FSE) for evaluation of PCL graft integrity. Each image was interpreted independently by two radiologists without knowledge of radiologic reports or clinical history. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.03.009DOI Listing
May 2019
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Improved visualization of the coronary arteries using motion correction during vasodilator stress CT myocardial perfusion imaging.

Eur J Radiol 2019 May 2;114:1-5. Epub 2019 Mar 2.

Departments of Medicine and Radiology, University of Chicago Medical Center, Chicago, IL, United States. Electronic address:

Background: Vasodilator stress computed tomography perfusion (sCTP) imaging is complementary to coronary CT angiography (CCTA), used to determine the hemodynamic significance of coronary artery disease. However, it requires a separate image acquisition due to motion artifacts caused by higher heart rates during stress, resulting in increased iodine contrast dose and radiation. We sought to determine whether a novel motion correction algorithm applied to stress images would improve the visualization of the coronary arteries to potentially allow CCTA + sCTP evaluation in a single scan. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.010DOI Listing

Can we predict lesion detection rates in second-look ultrasound of MRI-detected breast lesions? A systematic analysis.

Eur J Radiol 2019 Apr 11;113:96-100. Epub 2019 Feb 11.

Department of Biomedical Imaging and Image-guided Therapy,Medical University of Vienna, Austria. Electronic address:

Purpose: To predict detection rates (DR) in second-look ultrasound of MRI-detected breast lesions by systematically combining clinical and anthropomorphic features.

Methods: A total of 104 suspicious breast-lesions, that were initially detected on breast MRI and underwent subsequent SLU from January 2013 through December 2013, were evaluated in this retrospective analysis. All images were reviewed by an experienced radiologist for this study. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.008DOI Listing
April 2019
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Deep learning for segmentation of 49 selected bones in CT scans: First step in automated PET/CT-based 3D quantification of skeletal metastases.

Eur J Radiol 2019 Apr 1;113:89-95. Epub 2019 Feb 1.

Department of Translational Medicine, Lund University, Malmö, Sweden; Wallenberg Center for Molecular Medicine, Lund University, Malmö, Sweden.

Purpose: The aim of this study was to develop a deep learning-based method for segmentation of bones in CT scans and test its accuracy compared to manual delineation, as a first step in the creation of an automated PET/CT-based method for quantifying skeletal tumour burden.

Methods: Convolutional neural networks (CNNs) were trained to segment 49 bones using manual segmentations from 100 CT scans. After training, the CNN-based segmentation method was tested on 46 patients with prostate cancer, who had undergone F-choline-PET/CT and F-NaF PET/CT less than three weeks apart. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.028DOI Listing
April 2019
1 Read

Combination of breast imaging parameters obtained from F-FDG PET and CT scan can improve the prediction of breast-conserving surgery after neoadjuvant chemotherapy in luminal/HER2-negative breast cancer.

Eur J Radiol 2019 Apr 7;113:81-88. Epub 2019 Feb 7.

Department of Nuclear Medicine, Centre Antoine-Lacassagne, Nice, France; TIRO-UMR E 4320, University of Nice-Sophia-Antipolis, France.

Introduction: The luminal/Human Epidermal growth factor Receptor 2 (HER2) negative subtype of breast cancer has low chemo-sensitivity. When neoadjuvant chemotherapy (NAC) is indicated in this subtype, before a possible breast-conserving surgery (BCS), it is more reasonable to target tumor shrinkage than complete pathological tumor response. We aimed to identify breast and tumor Fluoro-deoxy-glucose (F-FDG) PET-CT scan imaging features for the early prediction of BCS after NAC in luminal/HER2 negative subtypes of breast cancer. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.005DOI Listing
April 2019
2 Reads

Diagnostic accuracy of shear wave elastography - Virtual touch imaging quantification in the evaluation of breast masses: Impact on ultrasonography's specificity and its ultimate clinical benefit.

Eur J Radiol 2019 Apr 10;113:74-80. Epub 2019 Feb 10.

Department of Gynecology and Obstetrics of Faculty of Medical Sciences of Campinas State University (UNICAMP), São Paulo, Brazil. Electronic address:

Objectives: To evaluate the diagnostic performance and the clinical benefit of Shear-Wave Elastography - Virtual Touch Imaging Quantification (SWE-VTIQ) as a complement to ultrasonography (US).

Methods: From October 2016 through Jun 2017, B-mode US and SWE-VTIQ were prospectively performed in 396 breast masses in 357 women who consented to undergo this study. Quantitative elastography values were recorded: V (maximum elasticity), V (median elasticity), V (ratio of V and surrounding parenchyma) and V (ratio of V and surrounding parenchyma). Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.004DOI Listing
April 2019
3 Reads

MR features based on LI-RADS identify cytokeratin 19 status of hepatocellular carcinomas.

Eur J Radiol 2019 Apr 31;113:7-14. Epub 2019 Jan 31.

Department of Radiology, Zhongshan Hospital, Fudan University, and Shanghai Medical Imaging Institute, Shanghai, China. Electronic address:

Objective: To retrospectively evaluate the value of MR features based on Liver Imaging Reporting and Data System (LI-RADS ver.2017) for identifying the status of cytokeratin (CK) 19 expression of HCC before surgery.

Methods: A total of 201 patients with 207 HCCs who underwent MR imaging were reviewed retrospectively. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.036DOI Listing
April 2019
2 Reads

Review of axillary web syndrome: What the radiologist should know.

Eur J Radiol 2019 Apr 4;113:66-73. Epub 2019 Feb 4.

Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medicine, 601 N. Caroline St., Suite 4120, Baltimore, MD, 21287, USA. Electronic address:

Axillary web syndrome is common after axillary surgery, frequently affecting breast cancer patients. In this condition, patients develop one or more linear bands of firm tissue, also known as "cords", in the axilla and arm, associated with pain and limited range of motion of the shoulder and arm. Radiologists may encounter this syndrome in patients referred for axillary or upper extremity ultrasound, and should be aware of the physical examination and ultrasound findings for accurate diagnosis. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.001DOI Listing
April 2019
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Time-resolved quantitative evaluation of diaphragmatic motion during forced breathing in a health screening cohort in a standing position: Dynamic chest phrenicography.

Eur J Radiol 2019 Apr 31;113:59-65. Epub 2019 Jan 31.

Department of Respiratory Medicine, Fukujuji Hospital, Japan Anti-Tuberculosis Association, 3-1-24 Matsuyama, Kiyose, Tokyo, 204-8522, Japan.

Objective: To assess diaphragmatic motion during forced breathing in a health screening center cohort by time-resolved quantitative analysis using dynamic chest radiography and demonstrate the characteristics and associations with demographics and pulmonary function of participants.

Materials And Methods: This prospective study includes 174 volunteers (99 males; median 57, range 36-93 years old) that underwent dynamic chest radiography with a flat panel detector system during forced breathing in a standing position. We automatically tracked and recorded the positions of the top of the diaphragms and the excursions on images of each participant and calculated peak motion speeds based on the data. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.034DOI Listing
April 2019
2 Reads

A comparison of the reproducibility of two cine-derived strain software programmes in disease states.

Eur J Radiol 2019 Apr 23;113:51-58. Epub 2019 Jan 23.

Dept of Cardiovascular Sciences, University of Leicester and NIHR Leicester Cardiovascular Biomedical Research Centre, Glenfield Hospital Leicester, UK.

Background: Systolic strain and peak-early diastolic strain rate (PEDSR) measure subclinical cardiac dysfunction. These parameters can be derived from cardiovascular magnetic resonance (CMR) cine images using new software packages, but the comparative test-retest reproducibility of these software in disease states is unknown. This study compared the test-retest reproducibility of strain measures derived from two software packages (feature-tracking software (FT) and tissue-tracking (TT)) in disease populations with preserved ejection fractions. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.026DOI Listing
April 2019
3 Reads

Predictive value of quantitative diffusion-weighted imaging and 18-F-FDG-PET in head and neck squamous cell carcinoma treated by (chemo)radiotherapy.

Eur J Radiol 2019 Apr 4;113:39-50. Epub 2019 Feb 4.

Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, the Netherlands.

Background And Purpose: In head and neck squamous cell carcinoma (HNSCC) (chemo)radiotherapy is increasingly used to preserve organ functionality. The purpose of this study was to identify predictive pretreatment DWI- and F-FDG-PET/CT-parameters for treatment failure (TF), locoregional recurrence (LR) and death in HNSCC patients treated by (chemo)radiotherapy.

Materials And Methods: We retrospectively included 134 histologically proven HNSCC patients treated with (chemo)radiotherapy between 2012-2017. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.031DOI Listing
April 2019
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Does patellar alignment or trochlear morphology predict worsening of patellofemoral disease within the first 5 years after anterior cruciate ligament reconstruction?

Eur J Radiol 2019 Apr 31;113:32-38. Epub 2019 Jan 31.

La Trobe Sport & Exercise Medicine Research Centre, La Trobe University, Bundoora, Australia; Institute of Anatomy, Paracelsus Medical University Salzburg & Nuremburg, Salzburg, Austria. Electronic address:

Purpose: We described patellofemoral alignment and trochlear morphology at one and five years after anterior cruciate ligament reconstruction (ACLR), and evaluated the associations between alignment and trochlear morphology (at one year) and worsening patellofemoral osteoarthritis (OA) features by five years. We also evaluated the associations between alignment and morphology to self-reported pain and function (Knee injury and Osteoarthritis Outcome Score, KOOS) at five years.

Materials And Methods: In this longitudinal observational study, we followed 73 participants (mean age 29[9] years, 40% women) from one- to five-years after ACLR. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473803PMC
April 2019
2 Reads

Comparison between linear and nonlinear machine-learning algorithms for the classification of thyroid nodules.

Eur J Radiol 2019 Apr 27;113:251-257. Epub 2019 Feb 27.

Department of Radiology, Shunde Hospital of Southern Medical University, Foshan, Guangdong, PR China. Electronic address:

Background: A key challenge in thyroid carcinoma is preoperatively diagnosing malignant thyroid nodules. The purpose of this study was to compare the classification performance of linear and nonlinear machine-learning algorithms for the evaluation of thyroid nodules using pathological reports as reference standard.

Methods: Ethical approval was obtained for this retrospective analysis, and the informed consent requirement was waived. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.029DOI Listing
April 2019
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Texture analysis of myocardial infarction in CT: Comparison with visual analysis and impact of iterative reconstruction.

Eur J Radiol 2019 Apr 27;113:245-250. Epub 2019 Feb 27.

Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistr. 100, CH-8091 Zurich, Switzerland.

Objectives: To compare texture analysis (TA) with subjective visual diagnosis of myocardial infarction (MI) in cardiac computed tomography (CT) and to evaluate the impact of iterative reconstruction (IR).

Methods: Ten patients (4 women, mean age 68 ± 11 years) with confirmed chronic MI and 20 controls (8 women, mean age 52 ± 11 years) with no cardiac abnormality underwent contrast-enhanced cardiac CT with the same protocol. Images were reconstructed with filtered back projection (FBP) and with advanced modeled IR at strength levels 3-5. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.037DOI Listing
April 2019
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Hallux valgus assessment on X-ray and Magnetic resonance Imaging (MRI): Correlation with qualitative soft tissue and internal derangement findings on MRI.

Eur J Radiol 2019 Apr 2;113:24-31. Epub 2019 Feb 2.

Radiology, UT Southwestern Medical Center, Dallas, TX, USA; Orthopaedic Surgery, UT Southwestern Medical Center, Dallas, TX, USA. Electronic address:

Aim: Radiographs (X-rays) are used for the preoperative assessment of hallux valgus (HV). Our purpose was to determine how well quantitative measurements of HV on radiographs and MRI correlate with the qualitative soft tissue and internal derangement findings on MRI.

Materials And Methods: After IRB approval, 56 consecutive patients with MRI and radiographs of the foot were retrospectively reviewed. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.01.035DOI Listing

Histogram analysis combined with morphological characteristics to discriminate adenocarcinoma in situ or minimally invasive adenocarcinoma from invasive adenocarcinoma appearing as pure ground-glass nodule.

Eur J Radiol 2019 Apr 26;113:238-244. Epub 2019 Feb 26.

Department of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China. Electronic address:

Objective: To construct a predictive model to discriminate adenocarcinoma in situ (AIS) or minimally invasive adenocarcinoma (MIA) from invasive adenocarcinoma (IAC) appearing as pure ground-glass nodules (pGGNs) using computed tomography (CT) histogram analysis combined with morphological characteristics and to evaluate its diagnostic performance.

Materials And Methods: Two hundred eighty-nine patients with surgically resected solitary pGGN and pathologically diagnosed with AIS, MIA, or IAC in our institution from January 2014 to May 2018 were enrolled in our study. Two hundred twenty-six pGGNs (79 AIS, 84 MIA, and 63 IAC) were randomly selected and assigned to a model-development cohort, and the remaining 63 pGGNs (11 AIS, 29 MIA and 23 IAC) were assigned to a validation cohort. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.034DOI Listing

Prenatal diagnosis of arachnoid cysts: MRI features and neurodevelopmental outcome.

Eur J Radiol 2019 Apr 22;113:232-237. Epub 2019 Feb 22.

Department of Pediatric Neurology, Sheba Medical Center, Tel Hashomer, Israel; Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objective: Arachnoid cysts (AC) are congenital lesions comprising 1% of all intracranial mass lesions. The aim of this study was to characterize arachnoid cysts and their neurodevelopmental outcome and to compare it with the outcome of children without AC.

Methods: This is a retrospective cohort study of arachnoid cysts detected prenatally by fetal MRI in 29 fetuses compared to a control group of 59 fetuses without arachnoid cyst who were examined by MRI. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.027DOI Listing
April 2019
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Comparison of PET/MRI with multiparametric MRI in diagnosis of primary prostate cancer: A meta-analysis.

Eur J Radiol 2019 Apr 21;113:225-231. Epub 2019 Feb 21.

Department of Radiology, West China Hospital of Sichuan University, Chengdu, 610041, Sichuan Province, China. Electronic address:

Objective: This meta-analysis aimed to compare the diagnostic performance of positron emission tomography (PET)/MRI using various radiotracers with multiparametric (mp) MRI for detection of primary prostate cancer (PCa).

Methods: A systematic literature search up to January 2019 was performed to identify studies that evaluated the diagnostic value of PET/MRI and mpMRI for detection of PCa in the same patient cohorts and had sufficient data to construct 2 × 2 contingency tables for true-positive (TP), false-positive (FP), false-negative (FN), and true-negative (TN) results. The quality of each study was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool, and pooled sensitivity (SEN) and specificity (SPE) were calculated. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.028DOI Listing

Cardiac magnetic resonance including parametric mapping in acute Takotsubo syndrome: Preliminary findings.

Eur J Radiol 2019 Apr 20;113:217-224. Epub 2019 Feb 20.

Department of Radiology, University of Bonn, Sigmund-Freud-Str. 25, 53127, Bonn, Germany. Electronic address:

Introduction: T1 and T2 mapping have been shown to be reliable markers of interstitial myocardial fibrosis, edema, and inflammation. The aim of this study was to evaluate myocardial involvement in acute phase Takotsubo syndrome using native and post-contrast T1 mapping, ECV fraction, and T2 mapping.

Material And Methods: We investigated 14 patients with acute Takotsubo syndrome and 14 healthy controls. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.026DOI Listing

Regional variation of ankle and hindfoot cartilage T2 mapping values at 3 T: A feasibility study.

Eur J Radiol 2019 Apr 16;113:209-216. Epub 2019 Feb 16.

Steadman Philippon Research Institute, 181 West Meadow Drive, Suite 1000, Vail, Colorado, 81657, USA. Electronic address:

Objective: To develop a method for T2 mapping of the entire tibiotalar/hindfoot articular surfaces and to examine regional T2 variation in asymptomatic volunteers, establishing necessary methods for future T2 mapping work in patients with ankle/hindfoot injury.

Materials And Methods: Twenty-six asymptomatic volunteers (11 female/13 male, aged 23-64 years in final analysis) underwent sagittal T2 mapping. Tibiotalar and hindfoot cartilage surfaces were segmented by two raters. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.011DOI Listing

Differentiation of liver abscess from liver metastasis using dual-energy spectral CT quantitative parameters.

Eur J Radiol 2019 Apr 19;113:204-208. Epub 2019 Feb 19.

GE Healthcare.

Objective: To explore the value of single source dual-energy spectral CT quantitative parameters in differential diagnosis of liver abscess and liver metastatic tumor.

Methods: Fifty-one patients with 73 liver lesions (28 liver abscesses and 45 liver metastases) underwent plain and contrast-enhanced spectral CT scans. The fat and blood concentrations and CT values of 40-140 keV monochromatic images were measured to calculate effective atomic number (Eff-Z) and a slope (K): [CT(40 keV)-CT(140 keV)/100] for the cystic component on the plain scan images. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.024DOI Listing
April 2019
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Comparative analysis of radiation dose and low contrast detail detectability using routine paediatric chest radiography protocols.

Eur J Radiol 2019 Apr 15;113:198-203. Epub 2019 Feb 15.

School of Health Sciences, University of Salford, Salford M6 6PU, United Kingdom.

Objectives: To compare low contrast detail (LCD) detectability and radiation dose for routine paediatric chest X-ray (CXR) imaging protocols among various hospitals.

Methods: CDRAD 2.0 phantom and medical grade polymethyl methacrylate (PMMA) slabs were used to simulate the chest region of four different paediatric age groups. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.017DOI Listing
April 2019
1 Read
2.369 Impact Factor

Unresectable pancreatic ductal adenocarcinoma: Role of CT quantitative imaging biomarkers for predicting outcomes of patients treated with chemotherapy.

Eur J Radiol 2019 Apr 11;113:188-197. Epub 2019 Feb 11.

Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China. Electronic address:

Objectives: The primary aim of this study was to determine if computed tomographic (CT) texture analysis measurements of the tumor are independently associated with progression-free survival (PFS) and overall survival (OS) in patients with unresectable pancreatic ductal adenocarcinoma (PDAC), including both unresectable locally advanced and metastatic PDAC, who were treated with chemotherapy.

Methods: After an institutional review board waiver was obtained, contrast material-enhanced CT studies in 41 patients with unresectable PDAC who underwent contrast-enhanced CT before chemotherapy between 2014 and 2017 were analyzed in terms of tumor texture, with quantification of mean gray-level intensity (Mean), entropy, mean of positive pixels (MPP), kurtosis, standard deviation (SD), and skewness for fine to coarse textures (spatial scaling factor (SSF) 0-6, respectively). The association between pretreatment and posttreatment texture parameters, as well as Δ value (difference between posttreatment and pretreatment texture parameters), and survival time was assessed by using Cox proportional hazards models and Kaplan-Meier analysis. Read More

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http://dx.doi.org/10.1016/j.ejrad.2019.02.009DOI Listing