3,697 results match your criteria European Journal of Ophthalmology[Journal]


Usher syndrome in a patient with Ellis-van Creveld syndrome.

Eur J Ophthalmol 2019 Apr 16:1120672119841778. Epub 2019 Apr 16.

1 Department of Ophthalmology, Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

Purpose: To describe a case of Ellis-van Creveld syndrome with concomitant Usher syndrome.

Methods: A 24-year-old lady with a diagnosis of Ellis-van Creveld syndrome came to our attention in 2015 complaining of nyctalopia. She underwent yearly ophthalmologic examinations, including visual acuity, dilated fundoscopy, optical coherence tomography and colour fundus photography. Read More

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http://journals.sagepub.com/doi/10.1177/1120672119841778
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http://dx.doi.org/10.1177/1120672119841778DOI Listing
April 2019
1 Read

The value of prednisolone acetate provocative test before intravitreal triamcinolone acetonide injections.

Eur J Ophthalmol 2019 Apr 12:1120672119842731. Epub 2019 Apr 12.

Department of Ophthalmology, Kasr El Aini Hospital, Cairo University, Cairo, Egypt.

Purpose: The aim of this study was to investigate the diagnostic value of a topical prednisolone acetate 1% provocative test for steroid-induced ocular hypertension before intravitreal triamcinolone acetonide injection.

Methods: This is a prospective, single-center, randomized controlled study at Kasr El Aini Hospital, Cairo University. Patients scheduled for intravitreal triamcinolone acetonide were enrolled and randomly allocated in a ratio 2:1 to either Group A: received prednisolone acetate provocative test and those who did not develop SIOH proceeded with intravitreal triamcinolone acetonide or Group B: did not receive prednisolone acetate provocative test and proceeded directly to intravitreal triamcinolone acetonide. Read More

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http://dx.doi.org/10.1177/1120672119842731DOI Listing
April 2019
1 Read

Evaluation of dynamic thiol-disulfide homeostasis in glaucoma patients and the correlation with retinal nerve fiber layer analysis.

Eur J Ophthalmol 2019 Apr 12:1120672119839582. Epub 2019 Apr 12.

3 Biochemistry Department, Ankara Atatürk Education and Research Hospital, Ankara, Turkey.

Purpose: The aim of this study was to evaluate thiol/disulfide homeostasis and ischemia-modified albumin levels with primary open-angle glaucoma, ocular hypertension, and control group; also to interpret the correlation between these biochemical parameters and retinal nerve fiber layer analysis.

Material And Methods: In a prospective cross-sectional study, 30 primary open-angle glaucoma cases, 30 ocular hypertension cases, and 30 control subjects were included in the study. Native thiol, total thiol, and disulfide measurements and disulfide/native thiol, disulfide/total thiol, and native thiol/total thiol ratios were evaluated as thiol-disulfide homeostasis. Read More

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http://dx.doi.org/10.1177/1120672119839582DOI Listing
April 2019
1 Read

Complement factor B gene polymorphisms and risk of age-related macular degeneration: A meta-analysis.

Eur J Ophthalmol 2019 Apr 12:1120672119840245. Epub 2019 Apr 12.

1 Department of Ophthalmology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, P.R. China.

Objective: To investigate the potential correlation between complement factor B polymorphisms and age-related macular degeneration.

Methods: We retrieved relevant articles systematically by searching PubMed and Web of Science databases. The pooled odds ratios and 95% confidence intervals were calculated for five complement factor B polymorphism rs641153, rs4151667, rs1048709, rs2072633, and rs12614 using data from included articles in both random effects and fixed effect models. Read More

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http://dx.doi.org/10.1177/1120672119840245DOI Listing

Widefield OCT angiography and ultra-widefield multimodal imaging of Susac syndrome.

Eur J Ophthalmol 2019 Apr 10:1120672119843281. Epub 2019 Apr 10.

Department of Ophthalmology, University Vita-Salute, IRCCS Ospedale San Raffaele, Milan, Italy.

The aim is to present the changes in ultra-widefield and widefield multimodal imaging, including optical coherence tomography angiography of a 33-year-old woman diagnosed with Susac syndrome, over 1 year of follow-up. Fundus examination and multimodal imaging revealed bilateral arterial occlusion of multiple vascular branches with retinal ischemia. Over 1 year follow-up, best-corrected visual acuity improved while retinal ischemia gradually resolved. Read More

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http://dx.doi.org/10.1177/1120672119843281DOI Listing

Anterior chamber aqueous flare is not a predictor for surgical closure of full-thickness idiopathic macular holes.

Eur J Ophthalmol 2019 Apr 10:1120672119843283. Epub 2019 Apr 10.

1 Department of Ophthalmology, University of Cologne, Cologne, Germany.

Purpose: To investigate the predictive value of preoperative anterior chamber aqueous flare levels measured by laser flare photometry for surgical success of idiopathic macular holes in addition to preoperative anatomic characteristics.

Methods: Records of 105 consecutive eyes with full-thickness idiopathic macular holes which underwent pars plana vitrectomy with internal limiting membrane peeling and sulfur hexafluoride 20% (SF20%) endotamponade were reviewed retrospectively. All patients underwent preoperative measurements of anterior chamber aqueous flare and anatomical idiopathic macular hole characteristics evaluated by optical coherence tomography: macular hole inner opening diameter, macular hole minimum linear diameter, macular hole base diameter, and macular hole height. Read More

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http://dx.doi.org/10.1177/1120672119843283DOI Listing

Polymerase chain reaction analysis of aqueous humor specimens in the diagnosis of cytomegalovirus retinitis in AIDS patients.

Eur J Ophthalmol 2019 Apr 10:1120672119841777. Epub 2019 Apr 10.

Beijing DiTan Hospital, Capital Medical University, Beijing, China.

Purpose: To determine the value of the polymerase chain reaction analysis of aqueous humor specimens as a tool to diagnose cytomegalovirus retinitis in AIDS patients.

Methods: In all, 63 AIDS patients were evaluated in this study. They were sorted into two diagnostic categories: eyes with active cytomegalovirus retinitis and eyes without active cytomegalovirus retinitis. Read More

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http://dx.doi.org/10.1177/1120672119841777DOI Listing

Ophthalmic, systemic, and genetic characteristics of patients with Wolfram syndrome.

Eur J Ophthalmol 2019 Apr 7:1120672119842489. Epub 2019 Apr 7.

2 Department of Ophthalmology, Sisli Hamidiye Etfal Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Purpose: To evaluate the ophthalmic, systemic, and genetic characteristics of patients with Wolfram syndrome.

Methods: In total, 13 patients with suspected or clinically diagnosed Wolfram syndrome underwent ophthalmic and systemic examinations and genetic analyses for Wolfram syndrome between August and October 2018.

Results: The mean age of the subjects was 24. Read More

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http://dx.doi.org/10.1177/1120672119842489DOI Listing
April 2019
3 Reads

Cataract extraction in patients with primary congenital glaucoma.

Eur J Ophthalmol 2019 Apr 7:1120672119841190. Epub 2019 Apr 7.

1 Ophthalmology Department, Clínico San Carlos Hospital, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.

Objective: To assess incidence and risk factors of cataract extraction in patients with primary congenital glaucoma, surgical outcome, and complications.

Material And Method: Retrospective cohort study, in which 108 patients with primary congenital glaucoma were included. Data collected were need for cataract extraction and at what age, intraocular pressure at diagnosis of primary congenital glaucoma, required antiglaucomatous surgeries, possible mutation in the CYP1B1 gene, and final visual acuity. Read More

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http://journals.sagepub.com/doi/10.1177/1120672119841190
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http://dx.doi.org/10.1177/1120672119841190DOI Listing
April 2019
7 Reads

Pupil cerclage technique for treatment of traumatic mydriasis.

Eur J Ophthalmol 2019 Apr 7:1120672119839304. Epub 2019 Apr 7.

Department of Ophthalmology, University of Padova, Padova, Italy.

Aim: The aim of this study is to evaluate the efficacy of pupil cerclage and a new variant of sliding knot technique for repairing traumatic mydriasis.

Design: This is a observational case series study.

Setting/methods: A series of consecutive patients affected by traumatic permanent mydriasis who underwent pupil cerclage were recruited at the Department of Ophthalmology of the University of Padova, Italy. Read More

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http://dx.doi.org/10.1177/1120672119839304DOI Listing
April 2019
2 Reads

A triad of retinal signs in Alport syndrome: The 'stair-case' fovea, choroidal thinning and peripheral schisis.

Eur J Ophthalmol 2019 Apr 7:1120672119841002. Epub 2019 Apr 7.

1 Department of Ophthalmology, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, UK.

Background: Alport syndrome is an inherited Type IV collagenopathy characterised by renal failure, hearing loss and ophthalmic manifestations such as lenticonus and dot-and-fleck retinopathy. New signs have been described which can be useful both for diagnosis and for prognosticating the risk of complications. This study examines and describes a triad comprising the unusual 'stair-case' foveal sign, together with choroidal thinning and late-stage peripheral schisis in a patient with Alport syndrome. Read More

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http://dx.doi.org/10.1177/1120672119841002DOI Listing
April 2019
2 Reads

Submacular cysticercosis.

Eur J Ophthalmol 2019 Apr 7:1120672119841542. Epub 2019 Apr 7.

1 Vitreo-Retina, Trauma and Uvea Services, All India Institute of Medical Sciences, New Delhi, India.

Ocular cysticercosis could involve subconjunctival space, anterior chamber, extraocular muscle, subretinal space, or vitreous. The presence of intraocular live cyst is a potential threat to visual acuity. The removal of the cyst in-toto is thus of importance to prevent inflammatory reaction and ocular damage. Read More

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http://dx.doi.org/10.1177/1120672119841542DOI Listing
April 2019
2 Reads

Cluster analysis of computerized visual field and optical coherence tomography-ganglion cell complex defects in high intraocular pressure patients or early stage glaucoma.

Eur J Ophthalmol 2019 Apr 5:1120672119841774. Epub 2019 Apr 5.

Ophthalmology Unit, NESMOS Department St. Andrea Hospital, Faculty of Medicine and Psychology, University of Rome "Sapienza," Rome, Italy.

Purpose:: The aim of the study is to evaluate the relationship between functional defects shown by cluster analysis of computerized visual field and anatomic defects from optical coherence tomography-ganglion cell complex examination in ocular hypertension or eyes affected by glaucoma.

Methods:: 205 eyes affected by ocular hypertension (intraocular pressure > 22 mmHg) or early stage glaucoma were enrolled. The age of the patients ranged from 26 to 87 years (average: 61. Read More

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http://dx.doi.org/10.1177/1120672119841774DOI Listing
April 2019
1 Read

Phacolytic glaucoma: A nearly forgotten entity.

Eur J Ophthalmol 2019 Apr 5:1120672119841972. Epub 2019 Apr 5.

1 Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Purpose:: To report a case of phacolytic glaucoma with rupture of anterior lens capsule in a case of hypermature cataract.

Methods:: Case report and literature review.

Results:: An 80-year-old woman presented with cloudiness and pain in the left eye for 1 day. Read More

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http://dx.doi.org/10.1177/1120672119841972DOI Listing
April 2019
9 Reads

Major factors affecting intraocular pressure spike after intravitreal ranibizumab injection: Vitreous reflux and its amount.

Eur J Ophthalmol 2019 Apr 5:1120672119836613. Epub 2019 Apr 5.

2 Department of Ophthalmology, Faculty of Medicine, Abant Izzet Baysal University, Bolu, Turkey.

Purpose:: The aim of this study was to assess the effect of vitreous reflux and its amount on short-term intraocular pressure after intravitreal injection of ranibizumab.

Methods:: The study included 316 eyes of 276 patients. Intraocular pressures were measured before intravitreal injection (preIOP), immediately after intravitreal injection (postIOP0), and 30 min after intravitreal injection (postIOP30). Read More

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http://dx.doi.org/10.1177/1120672119836613DOI Listing
April 2019
5 Reads

Isolated cilioretinal artery occlusion secondary to perinuclear antineutrophil cytoplasmic antibody vasculitis.

Eur J Ophthalmol 2019 Apr 5:1120672119841541. Epub 2019 Apr 5.

4 VitreoRetinal Surgery, PA, Edina, MN, USA.

Introduction:: Antineutrophil cytoplasm antibody-associated vasculitides encompass a diverse spectrum of autoimmune diseases characterized by necrotizing small vessel vasculitis. Ocular manifestations may be the presenting findings of antineutrophil cytoplasm antibody-associated vasculitides.

Methods:: Single, retrospective case study. Read More

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http://dx.doi.org/10.1177/1120672119841541DOI Listing
April 2019
2 Reads

Comments to: Valsalva retinopathy associated with intranasal cocaine abuse: A case report.

Eur J Ophthalmol 2019 Apr 4:1120672119841772. Epub 2019 Apr 4.

Ophthalmology Department, King's College Hospital, London, UK.

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http://dx.doi.org/10.1177/1120672119841772DOI Listing
April 2019
2 Reads

Ipsilateral metastatic choroidal melanoma responds to systemic immunotherapy.

Eur J Ophthalmol 2019 Apr 4:1120672119839925. Epub 2019 Apr 4.

1 The New York Eye Cancer Center, New York, NY, USA.

Purpose:: To report that metastatic choroidal melanoma (systemic and intraocular) can respond to systemic immunotherapy.

Methods:: In 2010, a 64-year-old woman with a choroidal melanoma was treated with palladium-103 plaque brachytherapy. Developing 2. Read More

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http://dx.doi.org/10.1177/1120672119839925DOI Listing
April 2019
2 Reads

Intraocular pressure control after trans-scleral intraocular lens fixation in glaucoma patients.

Eur J Ophthalmol 2019 Apr 4:1120672119840913. Epub 2019 Apr 4.

Department of Ophthalmology and Vision Sciences, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada.

Background:: Intraocular lens fixation surgery is associated with fluctuations in intraocular pressure. This may be significantly relevant in glaucoma patients.

Objectives:: To assess short- and medium-term intraocular pressure control after trans-scleral intraocular lens fixation surgery in glaucoma patients. Read More

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http://dx.doi.org/10.1177/1120672119840913DOI Listing
April 2019
1 Read

Standard and accelerated corneal cross-linking long-term results: A randomized clinical trial.

Eur J Ophthalmol 2019 Apr 4:1120672119839927. Epub 2019 Apr 4.

3 Noor Ophthalmology Research Center, Noor Eye Hospital, Tehran, Iran.

Purpose:: To compare long-term results between accelerated and standard corneal cross-linking protocols in the treatment of progressive keratoconus and compare their effectiveness between central (cone in the central 3 mm) and peripheral (cone beyond 3 mm) cases.

Methods:: In this randomized clinical trial, we compared 31 eyes treated with accelerated corneal cross-linking (18 mW/cm, 5 min) and 31 eyes treated with standard corneal cross-linking (3 mW/cm, 30 min), 16 central and 11 peripheral keratoconus in each group. In this report, 4-year changes in vision, refraction, topography, corneal biomechanics, and corneal cell count were evaluated. Read More

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http://dx.doi.org/10.1177/1120672119839927DOI Listing

Early results of micropulse transscleral cyclophotocoagulation for the treatment of glaucoma.

Eur J Ophthalmol 2019 Apr 2:1120672119839303. Epub 2019 Apr 2.

1 Department of Ophthalmology and Visual Science, Yale School of Medicine, New Haven, CT, USA.

Purpose:: To describe our clinical experience with the efficacy and safety of micropulse transscleral cyclophotocoagulation as a treatment for glaucoma.

Methods:: In this retrospective case series, we reviewed the charts of 95 consecutive patients with various glaucoma subtypes who underwent micropulse transscleral cyclophotocoagulation. Patients were offered micropulse transscleral cyclophotocoagulation if they had perimetric glaucoma refractory to intraocular pressure-lowering topical medications and who were poor candidates for traditional filtering surgery. Read More

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http://dx.doi.org/10.1177/1120672119839303DOI Listing
April 2019
11 Reads

Ocular bleeding in an undiagnosed hemophiliac neonate causing irreversible loss of vision: A case report with review of the literature.

Eur J Ophthalmol 2019 Apr 2:1120672119841188. Epub 2019 Apr 2.

1 Department of Ophthalmology, King Abdul-Aziz University Hospital, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Introduction:: Suprachoroidal hemorrhage is an unexpected complication after penetrating keratoplasty during childhood. We report the case of delayed suprachoroidal hemorrhage after penetrating keratoplasty in a neonate as the first manifestation of hemophilia.

Case Report:: A 4-day-old neonate was referred to our hospital because of bilateral corneal opacities present since birth. Read More

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http://journals.sagepub.com/doi/10.1177/1120672119841188
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http://dx.doi.org/10.1177/1120672119841188DOI Listing
April 2019
3 Reads

Short-term anterior chamber inflammation in phacoemulsification with and without Ex-Press glaucoma implant.

Eur J Ophthalmol 2019 Apr 2:1120672119839300. Epub 2019 Apr 2.

4 Department of Ophthalmology, Rabin Medical Center, Beilinson Hospital, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Purpose:: The aim of this study was to investigate the incidence of clinically significant anterior chamber inflammation in a combined surgery, namely, phacoemulsification and Ex-Press miniature glaucoma device implantation, compared to phacoemulsification alone.

Methods:: A retrospective comparative study of a consecutive series of 210 participants above 18 years of age diagnosed with significant cataract and who required glaucoma surgery, namely, Ex-Press miniature glaucoma device implantation or cataract alone in one or both eyes. All were operated on by a single experienced glaucoma surgeon in a single medical center. Read More

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http://dx.doi.org/10.1177/1120672119839300DOI Listing

Predicting visual outcomes in patients treated with aflibercept for neovascular age-related macular degeneration: Data from a real-world clinical setting.

Eur J Ophthalmol 2019 Apr 2:1120672119839299. Epub 2019 Apr 2.

1 Bradford Ophthalmology Research Network, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK.

Background/objectives:: There is a significant variation in the way neovascular age-related macular degeneration patients respond to anti-vascular endothelial growth factor treatment. Both the financial and time cost of treatment are significant. As such, being able to predict patient response to treatment is valuable. Read More

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http://dx.doi.org/10.1177/1120672119839299DOI Listing
April 2019
2 Reads

An unexpected case of iatrogenic Escherichia coli endogenous pan-endopthalmitis after ERCP-associated biliary sepsis: A case report.

Eur J Ophthalmol 2019 Mar 27:1120672119832833. Epub 2019 Mar 27.

2 Royal Alexandra Hospital, Paisley, UK.

Introduction:: Endogenous endopthalmitis is a diagnostically challenging ophthalmic and medical emergency. It has the ability to manifest at any age and is associated with a number of predisposing factors. The rapid progression of disease poses catastrophic risk for adverse outcomes both localised and systemic. Read More

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http://dx.doi.org/10.1177/1120672119832833DOI Listing

Fracture of a polyimide-elastimide posterior chamber intraocular lens following blunt orbital trauma.

Eur J Ophthalmol 2019 Mar 21:1120672119838125. Epub 2019 Mar 21.

1 Department of Ophthalmology, Meir Medical Center, Kfar Saba, Israel.

Purpose:: Fracture of a three-piece polyimide-elastimide intraocular lens at the optic-haptic junction following blunt trauma is a possible complication after cataract surgery. We report a case of an isolated posterior chamber intraocular lens fracture caused by direct ocular blunt trauma.

Case:: A 51-year-old patient underwent blunt orbital trauma caused by a raw chicken egg that was thrown at him, as he was walking. Read More

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http://dx.doi.org/10.1177/1120672119838125DOI Listing
March 2019
2 Reads

Three-year results from the Retro-IDEAL study: Real-world data from diabetic macular edema (DME) patients treated with ILUVIEN (0.19 mg fluocinolone acetonide implant).

Eur J Ophthalmol 2019 Mar 18:1120672119834474. Epub 2019 Mar 18.

16 Augenpraxisklinik Konstanz, Konstanz, Germany.

Introduction:: The Retro-IDEAL (ILUVIEN Implant for chronic DiabEtic MAcuLar edema) study is a retrospective study designed to assess real-world outcomes achieved with the ILUVIEN® (0.19 mg fluocinolone acetonide (FAc)) in patients with chronic diabetic macular edema (DME) in clinical practices in Germany.

Methods:: This study was conducted across 16 sites in Germany and involved 81 eyes (63 patients) with persistent or recurrent DME and a prior suboptimal response to a first-line intravitreal therapy (primarily anti-VEGF intravitreal therapies). Read More

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http://dx.doi.org/10.1177/1120672119834474DOI Listing

Effect of 2-year nutritional supplementation on progression of age-related macular degeneration.

Eur J Ophthalmol 2019 Mar 18:1120672119836007. Epub 2019 Mar 18.

9 ATS Sardegna, SASSL Nuoro, Italy.

Purpose:: To examine the effect of a long-term nutritional supplementation on age-related macular degeneration progression.

Methods:: In this prospective, double-blind, placebo-controlled study, 80 patients with intermediate age-related macular degeneration were randomized (2:1) to receive 1 tablet/day of a nutritional supplement containing a mixture of carotenoids, vitamins and omega-3 fatty acids or placebo. Age-related macular degeneration progression assessed by digital fundus photography (primary outcome) and best-corrected visual acuity were evaluated. Read More

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http://dx.doi.org/10.1177/1120672119836007DOI Listing

Switching from ranibizumab to aflibercept in choroidal neovascularization secondary to angioid streaks.

Eur J Ophthalmol 2019 Mar 18:1120672119838133. Epub 2019 Mar 18.

1 Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, University Paris-Est Créteil, Créteil, France.

Purpose:: To evaluate the efficacy of switching from intravitreal ranibizumab to intravitreal aflibercept in choroidal neovascularization secondary to angioid streaks.

Design:: Multicenter retrospective interventional case series.

Methods:: Patients previously treated with intravitreal ranibizumab with at least 12-month follow-up (M12) after switching (M0) to intravitreal aflibercept. Read More

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http://dx.doi.org/10.1177/1120672119838133DOI Listing
March 2019
2 Reads

Comments to: Accuracy of biometric formulae in hypermetropic patients undergoing cataract surgery.

Eur J Ophthalmol 2019 Mar 14:1120672119837084. Epub 2019 Mar 14.

Ophthalmology Department, King's College Hospital, London, UK.

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http://dx.doi.org/10.1177/1120672119837084DOI Listing
March 2019
1 Read

Trans-scleral posterior capsulorhexis in combined lens extraction and silicone oil removal.

Eur J Ophthalmol 2019 Mar 14:1120672119836002. Epub 2019 Mar 14.

Ophthalmology Department, Assiut University Hospital, Assiut, Egypt.

Aim:: The aim of this study was to study the safety and efficacy of posterior capsulorhexis in vitrectomized eyes undergoing combined phacoemulsification or irrigation/aspiration and silicone oil removal.

Methods:: This prospective non-randomized interventional study involved 115 silicone-filled eyes of 115 previously vitrectomized patients. All patients underwent combined phacoemulsification or underwent irrigation/aspiration and silicone oil removal, followed by foldable intraocular lens implantation combined with primary posterior trans-scleral capsulorhexis. Read More

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http://dx.doi.org/10.1177/1120672119836002DOI Listing
March 2019
2 Reads

Studying the role of 10-2 visual field test in different stages of glaucoma.

Eur J Ophthalmol 2019 Mar 14:1120672119836904. Epub 2019 Mar 14.

3 Students Eye Hospital, Cairo, Egypt.

Objective:: To assess the role of 10-2 visual field (VF) test in different stages of glaucoma.

Methods:: In our prospective comparative study, 24-2 and 10-2 VF tests were done for 115 eyes with different stages of glaucomatous damage or glaucoma suspects. Optical coherence tomography (OCT) was performed in 79 eyes. Read More

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http://dx.doi.org/10.1177/1120672119836904DOI Listing

Cornea guttata associated with special phenotypic variants of granular corneal dystrophy type 2 in a Chinese family.

Eur J Ophthalmol 2019 Mar 14:1120672119832176. Epub 2019 Mar 14.

Aier School of Ophthalmology, Central South University and Beijing Aier-Intech Eye Hospital, Beijing, P.R. China.

Purpose:: The aim of this study was to analyze the relevant gene mutations in a Chinese family with special phenotypic variants of granular corneal dystrophy type 2 with cornea guttata.

Methods:: A total of 11 individuals from the affected family underwent complete ophthalmic examination. Genomic DNA was extracted from peripheral leukocytes of affected and unaffected family members. Read More

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http://dx.doi.org/10.1177/1120672119832176DOI Listing
March 2019
3 Reads

Central perpendicular line in macular spectral-domain optical coherence tomography in five eyes.

Eur J Ophthalmol 2019 Mar 14:1120672119834476. Epub 2019 Mar 14.

Department of Ophthalmology, Brugmann University Hospital, Université Libre de Bruxelles, Brussels, Belgium.

Purpose:: The aim of this study is to report a rare spectral-domain optical coherence tomography finding in the macula.

Methods:: This is a descriptive consecutive case series. Patients diagnosed with hyperreflective central perpendicular line in the macular spectral-domain optical coherence tomography were included. Read More

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http://dx.doi.org/10.1177/1120672119834476DOI Listing

Conjunctival bleb compression as a treatment for hypotony post XEN45 implant in uveitic glaucoma.

Eur J Ophthalmol 2019 Mar 12:1120672119836339. Epub 2019 Mar 12.

Manchester Royal Eye Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.

Purpose:: Over-filtration and subsequent hypotony are recognised complications of penetrating glaucoma procedures, especially when augmented with antimetabolites. Patients with uveitis are especially at risk of hypotony and this can reduce the final acuity achieved, compromise surgical outcomes and adversely affect the inflammatory status. The incidence of hypotony following XEN45 implant insertion is higher for uveitic patients and we present a method of surgically addressing this hypotony with transconjunctival compression sutures that are placed over the overdraining XEN45 implant. Read More

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http://dx.doi.org/10.1177/1120672119836339DOI Listing

Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the lacrimal drainage system in two pediatric patients.

Eur J Ophthalmol 2019 Mar 12:1120672119837085. Epub 2019 Mar 12.

2 Department of Ophthalmology, Gazi University Medical School, Ankara, Turkey.

Primary non-Hodgkin lymphoma (NHL) of lacrimal drainage system (LDS) is quite rare in children, but it is important to expedite early diagnosis in an effort to alter possible life-threatening disease since they are usually misdiagnosed as chronic dacryocystitis. In the literature, there are few examples of tumors of LDS in children. The authors herein report two pediatric cases of extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) originating from lacrimal sac in an attempt to increase the knowledge about the clinical course of NHL of LDS. Read More

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http://dx.doi.org/10.1177/1120672119837085DOI Listing
March 2019
1 Read

Reproducibility of macular and optic nerve head vessel density measurements by swept-source optical coherence tomography angiography.

Eur J Ophthalmol 2019 Mar 12:1120672119834472. Epub 2019 Mar 12.

2 Centro Internacional de Oftalmología Avanzada, Madrid, Spain.

Purpose:: To assess the reproducibility of swept-source optical coherence tomography angiography (SS-OCTA) for macular and optic nerve head (ONH) vessel density (VD).

Methods:: Cross-sectional study using the Triton OCTA (Topcon, Tokyo, Japan), for VD (%) measurements in 40 eyes of 40 healthy subjects on two 6 × 6 mm scans of the macula and ONH across five subfields (central, superior, inferior, temporal, and nasal) at different segmentation levels: superficial capillary plexus (SCP), deep capillary plexus (DCP), outer retina, and choriocapillaris. Reproducibility values were summarized as intraclass correlation coefficients (ICCs) and coefficients of variations (CV). Read More

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http://dx.doi.org/10.1177/1120672119834472DOI Listing
March 2019
4 Reads

Intraobserver reproducibility and interobserver agreement of demarcation line depth measurements following corneal cross linking.

Eur J Ophthalmol 2019 Mar 12:1120672119835116. Epub 2019 Mar 12.

1 St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.

Purpose:: The aim of this study was to evaluate the intraobserver reproducibility of demarcation line depth measurement in keratoconic patients after epithelium-off corneal collagen cross linking and assess the interobserver variability/agreement among examiners of various experience levels.

Methods:: 56 eyes of 56 patients undergoing corneal collagen cross linking for progressive keratoconus were enrolled. After 4 weeks, all patients underwent an anterior segment optical coherence tomography (AS-OCT; CASIA SS-1000; Tomey, Nagoya, Japan) in the cross-linked eye by four masked examiners (two medical students (S1 and S2) and two corneal fellows (F1 and F2)) in order to identify and measure the demarcation line depth in experienced and non-experienced users. Read More

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http://dx.doi.org/10.1177/1120672119835116DOI Listing

Prevalence of diabetes and diabetic macular edema in patients undergoing senile cataract surgery in Italy: The DIabetes and CATaract study.

Eur J Ophthalmol 2019 Mar 11:1120672119830578. Epub 2019 Mar 11.

15 Department of Ophthalmology, University of Firenze, Florence, Italy.

Background:: The purpose of this study is to determine the prevalence of diabetes and diabetic macular edema in patients undergoing senile cataract surgery in Italy.

Methods:: It is a prospective, multicenter, cross-sectional study. Thirteen ophthalmic units equally distributed across the Italian territory have been involved in the study. Read More

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http://dx.doi.org/10.1177/1120672119830578DOI Listing
March 2019
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Changes in conjunctival epithelial cells after treatment with 0.2% xanthan gum eye drops in mild-moderate dry eye.

Eur J Ophthalmol 2019 Mar 11:1120672119833278. Epub 2019 Mar 11.

4 SIFI SpA, Catania, Italy.

Purpose:: To study the effects of xanthan gum eye drops on the ocular surface and conjunctival cytology of patients with mild-moderate dry eye.

Methods:: This prospective, double-masked, controlled trial included 30 patients (age > 60 and Ocular Surface Disease Index score >12 and <33), divided into two groups of 15 subjects and treated with 0.2% xanthan gum eye drops (group 1) or 0. Read More

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http://dx.doi.org/10.1177/1120672119833278DOI Listing

Neuroprotective effects of topical coenzyme Q10 + vitamin E in mechanic optic nerve injury model.

Eur J Ophthalmol 2019 Mar 11:1120672119833271. Epub 2019 Mar 11.

5 Department of Biochemistry, Gazi University Faculty of Medicine, Ankara, Turkey.

Purpose:: We aimed to create mechanic optic nerve injury model in rats and investigate the neuroprotective effects of topical Coenzyme Q10 + Vitamin E (CoQ + Vit.E) molecules on retinal ganglion cells.

Methods:: Mechanic optic nerve injury model was created in the right eyes of rats (n = 12). Read More

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http://dx.doi.org/10.1177/1120672119833271DOI Listing
March 2019
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Oculofacial alterations in NBAS-SOPH like mutations: Case report.

Eur J Ophthalmol 2019 Mar 8:1120672119836335. Epub 2019 Mar 8.

2 Department of Clinical Sciences and Community Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Multimedica, University of Milan, Eye Clinic San Giuseppe Hospital, Milan, Italy.

Purpose:: To describe the clinical features of a rare case of NBAS-SOPH-like mutations; to emphasize special aspects of the ocular and oro-facial regions.

Methods:: Case report.

Case Description:: We present a 5-year-old girl initially examined for her dysmorphic features, mental delay, strabismus, and high myopia. Read More

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http://dx.doi.org/10.1177/1120672119836335DOI Listing
March 2019
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Three-year follow-up of intrastromal corneal ring segment implantation in central keratoconus with regular astigmatism: 'Bow-tie' shape.

Eur J Ophthalmol 2019 Mar 8:1120672119835397. Epub 2019 Mar 8.

2 Faculty of Optics and Optometry, Complutense University of Madrid, Madrid, Spain.

Purpose:: To assess the outcomes of implanting Ferrara-type intrastromal corneal ring segments in central 'bow-tie'-shaped keratoconus over 3 years of follow-up.

Methods:: A total of 20 eyes with central 'bow-tie'-shaped keratoconus were evaluated before and after implanting Ferrara-type intrastromal corneal ring segments (AJL Ophthalmic, Spain). LogMAR uncorrected distance visual acuity and best corrected distance visual acuity and residual refractive errors analysed using vector analysis were recorded preoperatively, at 6 months, 1 year, and 3 years postoperatively. Read More

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http://dx.doi.org/10.1177/1120672119835397DOI Listing
March 2019
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The effect of mydriasis on moderate-to-high myopic eyes with implantable collamer lenses V4 and V4c.

Eur J Ophthalmol 2019 Mar 8:1120672119831218. Epub 2019 Mar 8.

1 Department of Ophthalmology, Shanghai Ninth People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.

Purpose:: To evaluate the vault change and anterior segment movement induced by mydriasis in moderate-to-high myopic eyes with implantable collamer lenses (ICL).

Setting:: Shanghai, China.

Design:: A prospective consecutive observational study. Read More

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http://dx.doi.org/10.1177/1120672119831218DOI Listing
March 2019
3 Reads

Femtosecond-assisted laser in situ keratomileusis for high myopia correction: Long-term follow-up outcomes.

Eur J Ophthalmol 2019 Mar 8:1120672119834478. Epub 2019 Mar 8.

1 Department of Cornea and Refractive Surgery, Vissum, Alicante, Spain.

Objective:: Report the outcomes of laser in situ keratomileusis (LASIK) for high myopia correction after long-term follow-up.

Methods:: Retrospective, consecutive, clinical study including 70 eyes that underwent LASIK using a 500 Hertz (Hz) repetition rate excimer laser and femtosecond technology for flap creation. Visual, refractive, corneal aberrations, and correlation among the variables were evaluated during 3 years. Read More

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http://dx.doi.org/10.1177/1120672119834478DOI Listing

Comparison of incidence of repositioning surgery to correct misalignment with three toric intraocular lenses.

Eur J Ophthalmol 2019 Mar 6:1120672119834469. Epub 2019 Mar 6.

10 Sugita Eye Clinic, Tokyo, Japan.

Purpose:: To compare the incidence of re-orientating surgery to improve misalignment of three models of acrylic toric intraocular lenses: AcrySof toric intraocular lens (Alcon Laboratories, Inc.), TECNIS toric intraocular lens (Johnson & Johnson Vision, Inc.) and HOYA 355 toric intraocular lens (HOYA). Read More

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http://dx.doi.org/10.1177/1120672119834469DOI Listing

Multimodal imaging in an idiopathic spontaneously absorbed cataractous lens: A rare case report.

Eur J Ophthalmol 2019 Mar 6:1120672119833558. Epub 2019 Mar 6.

Department of Ophthalmology, Sri Sankaradeva Nethralaya, Guwahati, India.

Purpose:: To report an unusual and rare case of idiopathic spontaneous absorption of the cataractous lens and its multimodal imaging features.

Methods:: A 56-year-old female presented with a complaint of diminution of vision in both eyes (OU). Slit lamp examination of the right eye (OD) revealed Morgagnian cataract with a normal anterior segment. Read More

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http://dx.doi.org/10.1177/1120672119833558DOI Listing

Bilateral decompression retinopathy after deep sclerectomy with mitomycin C in a child with tubulointerstitial nephritis and uveitis syndrome.

Eur J Ophthalmol 2019 Mar 6:1120672119832177. Epub 2019 Mar 6.

Department of Ophthalmology, Ramón y Cajal Hospital, Ramón y Cajal Institute of Health Research (IRYCIS), Madrid, Spain.

Introduction:: To report the first case of bilateral ocular decompression retinopathy after uneventful non-perforating deep sclerectomy with mitomycin C in a child with tubulointerstitial nephritis and uveitis syndrome.

Case Description:: An 8-year-old girl affected by tubulointerstitial nephritis and uveitis syndrome developed ocular hypertension (45 mmHg in the right eye and 42 mmHg in the left eye) associated with recurrent episodes of uveitis and chronic use of steroids despite maximum hypotensive medical treatment. Bilateral non-perforating deep sclerectomy with mitomycin C (0. Read More

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http://journals.sagepub.com/doi/10.1177/1120672119832177
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http://dx.doi.org/10.1177/1120672119832177DOI Listing
March 2019
4 Reads

Correlation analysis of fundus autofluorescence, spectral domain optical coherence tomography, and visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept.

Eur J Ophthalmol 2019 Mar 6:1120672119833267. Epub 2019 Mar 6.

5 Facultad de Ciencias de la Salud, Universidad Anahuac Mexico Norte, Mexico City, Mexico.

Purpose:: The aim of this study was to evaluate the correlations between fundus autofluorescence and morphologic parameters as well as visual function in patients with diabetic macular oedema treated with intravitreal ziv-aflibercept.

Methods:: A total of 34 eyes of 20 patients with untreated diabetic macular oedema received an intravitreal injection of ziv-aflibercept at baseline, and 1 and 2 months later. The baseline, 1-month, and two-month best corrected visual acuity determination, contrast sensitivity, spectral domain optical coherence tomography, mean central macular thickness, mean macular cube volume, mean macular cube average thickness, and fundus autofluorescence (decreased, normal, or increased; and single or multiple spots) were measured. Read More

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http://dx.doi.org/10.1177/1120672119833267DOI Listing

Optic coherence tomography angiography follow-up in a case of Purtscher-like retinopathy due to atypical hemolytic uremic syndrome.

Eur J Ophthalmol 2019 Mar 6:1120672119833277. Epub 2019 Mar 6.

Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain.

Purpose:: To report a case of Purtscher-like retinopathy due to atypical hemolytic uremic syndrome and the changes seen in the optical coherence tomography angiography before and after treatment with eculizumab.

Case Description:: A 22-year-old man with an unremarkable medical history presented with acute, bilateral blurred vision and headache of 1-week duration. Best corrected visual acuity of 20/50 and 20/40, respectively, in the patient's right eye and left eye. Read More

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http://dx.doi.org/10.1177/1120672119833277DOI Listing
March 2019
2 Reads