3,959 results match your criteria European Journal of Epidemiology[Journal]


Quantification of biological age as a determinant of age-related diseases in the Rotterdam Study: a structural equation modeling approach.

Eur J Epidemiol 2019 Apr 13. Epub 2019 Apr 13.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA.

Chronological age alone is not a sufficient measure of the true physiological state of the body. The aims of the present study were to: (1) quantify biological age based on a physiological biomarker composite model; (2) and evaluate its association with death and age-related disease onset in the setting of an elderly population. Using structural equation modeling we computed biological age for 1699 individuals recruited from the first and second waves of the Rotterdam study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00497-3DOI Listing

Generalizing from the results of randomized studies of treatment: Can non-randomized studies be of help?

Authors:
Noel S Weiss

Eur J Epidemiol 2019 Apr 11. Epub 2019 Apr 11.

University of Washington, Seattle, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00516-3DOI Listing

Maternal proximity to extremely low frequency electromagnetic fields and risk of birth defects.

Eur J Epidemiol 2019 Apr 11. Epub 2019 Apr 11.

National Collaborating Centre for Environmental Health, British Columbia Centre for Disease Control, Vancouver, Canada.

Causes of birth defects are unclear, and the association with electromagnetic fields is inconclusive. We assessed the relationship between residential proximity to extremely low frequency electromagnetic fields from power grids and risk of birth defects. We analyzed a population-based sample of 2,164,246 infants born in Quebec, Canada between 1989 and 2016. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-019-00518-1
Publisher Site
http://dx.doi.org/10.1007/s10654-019-00518-1DOI Listing
April 2019
3 Reads

Interaction between lifestyle and genetic susceptibility in myopia: the Generation R study.

Eur J Epidemiol 2019 Apr 3. Epub 2019 Apr 3.

Department of Ophthalmology, Erasmus University Medical Centre, Room Na-2808, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

Myopia is a refractive error of the eye caused by a complex interplay between nature and nurture. The aim of this study was to investigate whether environmental risk factors can influence the genetic effect in children developing myopia. A total of 3422 children participating in the birth-cohort study Generation R underwent an extensive eye examination at 9 years with measurements of refractive error and axial length corneal radius ratio (AL/CR). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00512-7DOI Listing

Being born in the aftermath of World War II increases the risk for health deficit accumulation in older age: results from the KORA-Age study.

Eur J Epidemiol 2019 Apr 2. Epub 2019 Apr 2.

Institute for Medical Information Processing, Biometry and Epidemiology, Ludwig-Maximilians-Universität München, Marchioninistr. 15, Munich, Germany.

Morbidity trends may result from cohort experiences in critical developmental age. Our objective was to compare the health status of 65-71 year-olds who were in critical developmental age before (1937-June 1945), during (June 1945-June 1948) and after (June 1948-1950) the early reconstruction and food crisis (ERFC) period in Germany following World War II. Data originate from the KORA (Cooperative Health Research in the Region of Augsburg)-Age study in Southern Germany. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00515-4DOI Listing

The longitudinal integrated database for health insurance and labour market studies (LISA) and its use in medical research.

Eur J Epidemiol 2019 Apr 30;34(4):423-437. Epub 2019 Mar 30.

Clinical Epidemiology Unit, Department of Medicine Stockholm, Karolinska Institutet, Stockholm, Sweden.

Education, income, and occupation are factors known to affect health and disease. In this review we describe the Swedish Longitudinal Integrated Database for Health Insurance and Labour Market Studies (LISA, Longitudinell Integrationsdatabas för Sjukförsäkrings- och Arbetsmarknadsstudier). LISA covers the adult Swedish population aged ≥ 16 years registered on December 31 each year since 1990 (since 2010 individuals aged ≥ 15 years). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00511-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451717PMC

Blood pressure, hypertension and the risk of abdominal aortic aneurysms: a systematic review and meta-analysis of cohort studies.

Eur J Epidemiol 2019 Mar 22. Epub 2019 Mar 22.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, St. Mary's Campus, Norfolk Place, Paddington, London, W2 1PG, UK.

Abdominal aortic aneurysms (AAA) are fatal in 80% of the cases when ruptured. Hypertension has been considered a potential risk factor for AAA; but the findings from prospective cohort studies have not been entirely consistent, nor have they been summarised in a comprehensive meta-analysis. Our aim was to conduct a systematic review and meta-analysis of cohort studies of the association between blood pressure, hypertension and AAA to clarify the strength and shape of these associations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00510-9DOI Listing
March 2019
1 Read

Nutritional epidemiology, extinction or evolution? It is all about balance and moderation.

Eur J Epidemiol 2019 Apr;34(4):333-335

Institute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00514-5DOI Listing

Missing girls among deliveries from Indian and Chinese mothers in Spain 2007-2015.

Eur J Epidemiol 2019 Mar 20. Epub 2019 Mar 20.

Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Avenida Monforte de Lemos, 5, 28029, Madrid, Spain.

Deliveries from Indian and Chinese mothers present a higher than expected male:female ratio in their own countries, in northern Europe, EEUU and Canada. No studies have been carried out in southern European countries. We explored whether the high male-to-female ratio common in Indian and Chinese communities, also exists among families from those regions who live in Spain. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-019-00513-6
Publisher Site
http://dx.doi.org/10.1007/s10654-019-00513-6DOI Listing
March 2019
5 Reads

Birth seasonality and risk of autism spectrum disorder.

Eur J Epidemiol 2019 Mar 20. Epub 2019 Mar 20.

Department of Psychiatry and Department of Preventive Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Season of birth has been hypothesized to be a risk factor for autism spectrum disorder (ASD). However, the evidence has been mixed and limited due to methodological challenges. We examine ASD birth trends for 5,464,628 births across 5 countries. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-019-00506-5
Publisher Site
http://dx.doi.org/10.1007/s10654-019-00506-5DOI Listing
March 2019
3 Reads

The long and winding road to causality.

Authors:
Olaf M Dekkers

Eur J Epidemiol 2019 Mar 18. Epub 2019 Mar 18.

Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-019-00507-4
Publisher Site
http://dx.doi.org/10.1007/s10654-019-00507-4DOI Listing
March 2019
2 Reads

The application of six dietary scores to a Middle Eastern population: a comparative analysis of mortality in a prospective study.

Eur J Epidemiol 2019 Apr 18;34(4):371-382. Epub 2019 Mar 18.

Digestive Oncology Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background The associations between dietary indices and mortality have not been evaluated in populations from the Middle East, which have different dietary patterns compared to the US and Europe. In this study, we evaluated the association between six dietary indices and mortality in the Golestan Cohort Study (GCS) in Iran, which is the largest prospective study in the Middle East with 50,045 participants. Methods The six dietary indices, namely the Healthy Eating Index (HEI-2015), Alternative Healthy Eating Index (AHEI-2010), Alternative Mediterranean Diet (AMED), Dietary Approach to Stop Hypertension created by Fung (DASH-Fung) and Mellen (DASH-Mellen), and the World Cancer Research Fund (WCRF/AICR) index, were applied to data from a food frequency questionnaire, computed and divided into quintiles. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00508-3DOI Listing
April 2019
26 Reads
5.339 Impact Factor

The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects.

Eur J Epidemiol 2019 Mar 18;34(3):279-300. Epub 2019 Mar 18.

Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK.

The impact of many unfavorable childhood traits or diseases, such as low birth weight and mental disorders, is not limited to childhood and adolescence, as they are also associated with poor outcomes in adulthood, such as cardiovascular disease. Insight into the genetic etiology of childhood and adolescent traits and disorders may therefore provide new perspectives, not only on how to improve wellbeing during childhood, but also how to prevent later adverse outcomes. To achieve the sample sizes required for genetic research, the Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia were established. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00502-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447695PMC
March 2019
6 Reads
5.339 Impact Factor

Preconceptional paternal antiepileptic drugs use and risk of congenital anomalies in offspring: a nationwide cohort study.

Eur J Epidemiol 2019 Mar 13. Epub 2019 Mar 13.

Department of Clinical Epidemiology, Aarhus University Hospital, 8200, Aarhus, Denmark.

Recent studies have shown that certain pharmacological agents used by fathers before conception may increase the risk of adverse neonatal outcomes in offspring. However, little is known about the effect of paternal use of antiepileptic drugs (AEDs) on congenital anomalies in children. Based on Danish national registers, we conducted a cohort study of 733, 282 singletons born from 1997 to 2008, with follow-up throughout 2013. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00509-2DOI Listing

Umbrella reviews: what they are and why we need them.

Eur J Epidemiol 2019 Mar 9. Epub 2019 Mar 9.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00505-6DOI Listing

Theory meets practice: a commentary on VanderWeele's 'principles of confounder selection'.

Eur J Epidemiol 2019 Mar 6;34(3):221-222. Epub 2019 Mar 6.

Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00495-5DOI Listing
March 2019
3 Reads

Principles of confounder selection.

Eur J Epidemiol 2019 Mar 6;34(3):211-219. Epub 2019 Mar 6.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, 02115, USA.

Selecting an appropriate set of confounders for which to control is critical for reliable causal inference. Recent theoretical and methodological developments have helped clarify a number of principles of confounder selection. When complete knowledge of a causal diagram relating all covariates to each other is available, graphical rules can be used to make decisions about covariate control. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00494-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447501PMC
March 2019
3 Reads

The disjunctive cause criterion by VanderWeele: An easy solution to a complex problem?

Eur J Epidemiol 2019 Mar 5;34(3):223-224. Epub 2019 Mar 5.

Department of Epidemiology, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00501-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447512PMC

Blood-brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals.

Eur J Epidemiol 2019 Mar 4. Epub 2019 Mar 4.

Department of Clinical Biochemistry KB 3011, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark.

To test whether genetic variants in PICALM, BIN1, CD2AP, and RIN3-suggested to be involved in blood-brain barrier amyloid-β transcytosis pathways-associate with Alzheimer's disease, all dementia, suggested vascular dementia, and stroke, and whether such associations are independent of the strong ε4 APOE risk allele. In a prospective cohort study of 74,754 individuals from the general population we genotyped PICALM (rs10792832), BIN1 (rs6733839), CD2AP (rs10948363), and RIN3 (rs10498633), and generated a weighted and a simple allele score. Multifactorially adjusted hazard ratios for the fourth quartile versus the first quartile of the weighted allele score were 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00498-2DOI Listing
March 2019
1 Read

Guidelines and recommendations for ensuring Good Epidemiological Practice (GEP): a guideline developed by the German Society for Epidemiology.

Eur J Epidemiol 2019 Mar 4;34(3):301-317. Epub 2019 Mar 4.

Unit "Prevention of Work-Related Disorders", Division "Work and Health", BAuA: Federal Institute for Occupational Safety and Health, Noeldnerstr. 40-42, 10317, Berlin, Germany.

Objective: To revise the German guidelines and recommendations for ensuring Good Epidemiological Practice (GEP) that were developed in 1999 by the German Society for Epidemiology (DGEpi), evaluated and revised in 2004, supplemented in 2008, and updated in 2014.

Methods: The executive board of the DGEpi tasked the third revision of the GEP. The revision was arrived as a result of a consensus-building process by a working group of the DGEpi in collaboration with other working groups of the DGEpi and with the German Association for Medical Informatics, Biometry and Epidemiology, the German Society of Social Medicine and Prevention (DGSMP), the German Region of the International Biometric Society (IBS-DR), the German Technology, Methods and Infrastructure for Networked Medical Research (TMF), and the German Network for Health Services Research (DNVF). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00500-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447506PMC
March 2019
1 Read

Adherence to the Mediterranean diet and risk of stroke and stroke subtypes.

Eur J Epidemiol 2019 Apr 2;34(4):337-349. Epub 2019 Mar 2.

Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.

Several meta-analyses including a small number of cohorts showed inverse associations between the Mediterranean Diet (MedDiet) and risk of stroke. However, it remains unclear whether such a relation varies by region of the study population or by major subtypes of stroke. We searched PubMed and EMBASE databases for relevant studies and we further included unpublished results from the Singapore Chinese Health Study (N = 57,078) and the Seguimiento Universidad de Navarra (SUN) study (N = 12,670). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00504-7DOI Listing

Prevalence of overweight and obesity in Western countries: discrepancies in published estimates.

Eur J Epidemiol 2019 Mar 2. Epub 2019 Mar 2.

Collaboration for Outcomes Research and Evaluation, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, Canada.

Two papers were extracted and pooled data from published sources were used to estimate the distribution of BMI values for adults living in many countries around the world. The NCD Risk Factor Collaboration and the Global Burden of Disease Study 2013 presented data for 200 and 188 countries, respectively. We extracted estimates from the two datasets for the prevalences of overweight and obesity in 28 Western countries. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00503-8DOI Listing
March 2019
3 Reads

Identifying dementia outcomes in UK Biobank: a validation study of primary care, hospital admissions and mortality data.

Eur J Epidemiol 2019 Feb 26. Epub 2019 Feb 26.

Centre for Medical Informatics, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.

Prospective, population-based studies that recruit participants in mid-life are valuable resources for dementia research. Follow-up in these studies is often through linkage to routinely-collected healthcare datasets. We investigated the accuracy of these datasets for dementia case ascertainment in a validation study using data from UK Biobank-an open access, population-based study of > 500,000 adults aged 40-69 years at recruitment in 2006-2010. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00499-1DOI Listing
February 2019

Expanding disease and undermining the ethos of medicine.

Authors:
Bjørn Hofmann

Eur J Epidemiol 2019 Feb 22. Epub 2019 Feb 22.

Department for the Health Sciences, Norwegian University of Science and Technology (NTNU), Gjovik, Norway.

The expansion of the concept of disease poses problems for epidemiology. Certainly, new diseases are discovered and more people are treated earlier and better. However, the historically unprecedented expansion is criticised for going too far. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00496-4DOI Listing
February 2019

Oxidative stress and epigenetic mortality risk score: associations with all-cause mortality among elderly people.

Eur J Epidemiol 2019 May 15;34(5):451-462. Epub 2019 Feb 15.

Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120, Heidelberg, Germany.

Oxidative stress (OS) has been found to be related to accelerated aging and many aging-related health outcomes. Recently, an epigenetic "mortality risk score" (MS) based on whole blood DNA methylation at 10 mortality-related CpG sites has been demonstrated to be associated with all-cause mortality. This study aimed to address the association between OS and MS, and to assess and compare their performance in the prediction of all-cause mortality. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00493-7DOI Listing
May 2019
1 Read

Unreformed nutritional epidemiology: a lamp post in the dark forest.

Eur J Epidemiol 2019 Apr;34(4):327-331

Meta-Research Innovation Center at Stanford (METRICS), and Departments of Medicine, Health Research and Policy, Biomedical Data Science, and Statistics, Stanford University, 1265 Welch Road, Medical School Office Building, Room X306, Stanford, CA, 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00487-5DOI Listing
April 2019
1 Read

Cystic echinococcosis in unaccompanied minor refugees from Afghanistan and the Middle East to Germany, July 2016 through June 2017.

Eur J Epidemiol 2019 Feb 9. Epub 2019 Feb 9.

Institute of Tropical Medicine and International Health, Charité Universitätsmedizin, Augustenburgerplatz 1, 13353, Berlin, Germany.

Cystic echinococcosis (CE) is not covered by current refugee screening protocols. After we had detected CE among several refugees attending our clinic from Afghanistan and the Middle East, serological examinations for CE were performed for apparently healthy unaccompanied minor refugees from these regions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00492-8DOI Listing
February 2019
3 Reads

The association between weight at birth and breast cancer risk revisited using Mendelian randomisation.

Eur J Epidemiol 2019 Feb 8. Epub 2019 Feb 8.

Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.

Observational studies suggest that higher birth weight (BW) is associated with increased risk of breast cancer in adult life. We conducted a two-sample Mendelian randomisation (MR) study to assess whether this association is causal. Sixty independent single nucleotide polymorphisms (SNPs) known to be associated at P < 5 × 10 with BW were used to construct (1) a 41-SNP instrumental variable (IV) for univariable MR after removing SNPs with pleiotropic associations with other breast cancer risk factors and (2) a 49-SNP IV for multivariable MR after filtering SNPs for data availability. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00485-7DOI Listing
February 2019
11 Reads
5.339 Impact Factor

"Bad luck" hypothesis and cancer prevention: translating the debate to more actions.

Authors:
Mingyang Song

Eur J Epidemiol 2019 May 7;34(5):447-449. Epub 2019 Feb 7.

Departments of Epidemiology and Nutrition, Harvard T.H. Chan School of Public Health, 667 Huntington Avenue, Kresge 906A, Boston, MA, 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00489-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458059PMC

Asthma and selective migration from farming environments in a three-generation cohort study.

Eur J Epidemiol 2019 Feb 7. Epub 2019 Feb 7.

Department of Public Health, Danish Ramazzini Centre, Aarhus University, Bartholins Alle 2, Building 1260, 8000, Aarhus C, Denmark.

Individuals raised on a farm appear to have less asthma than individual raised elsewhere. However, selective migration might contribute to this as may also the suggested protection from farm environment. This study investigated if parents with asthma are less likely to raise their children on a farm. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00491-9DOI Listing
February 2019
4 Reads

Nutritional epidemiology: forest, trees and leaves.

Eur J Epidemiol 2019 Apr 6;34(4):319-325. Epub 2019 Feb 6.

Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Ioannidis has stated that the field of nutritional epidemiology has generated confusion and numerous implausible findings and is in need of radical reform. One of the reforms he proposes is to conduct analyses that take into account the "totality for all nutritional factors measured". This approach is based on isolating and reducing diet into numerous independent variables with little regard to prior knowledge or the interrelations among dietary components, and relying on a "discovery" approach. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00488-4DOI Listing

Premenopausal cardiovascular disease and age at natural menopause: a pooled analysis of over 170,000 women.

Eur J Epidemiol 2019 Mar 5;34(3):235-246. Epub 2019 Feb 5.

School of Public Health, University of Queensland, 288 Herston Road (corner of Herston Rd and Wyndham St), Brisbane, QLD, 4006, Australia.

Early menopause is associated with an increased risk of subsequent cardiovascular disease (CVD). Few studies have investigated the converse. We examined whether premenopausal CVD events are associated with early age at menopause. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00490-wDOI Listing
March 2019
2 Reads

The meaning of confounding adjustment in the presence of multiple versions of treatment: an application to organ transplantation.

Eur J Epidemiol 2019 Mar 23;34(3):225-233. Epub 2019 Jan 23.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Causal inference for treatments with many versions requires a careful specification of the versions of treatment. Specifically, the existence of multiple relevant versions of treatment has implications for the selection of confounders. To illustrate this, we estimate the effect of organ transplantation using grafts from donors who died due to anoxic drug overdose, on recipient graft survival in the US. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00484-8DOI Listing
March 2019
1 Read

Red meat, processed meat, and other dietary protein sources and risk of overall and cause-specific mortality in The Netherlands Cohort Study.

Eur J Epidemiol 2019 Apr 23;34(4):351-369. Epub 2019 Jan 23.

Department of Epidemiology, GROW-School for Oncology and Developmental Biology, Maastricht University Medical Centre, P.O. Box 616, 6200 MD, Maastricht, The Netherlands.

Processed meat and red meat have been associated with increased mortality, but studies are inconsistent and few have investigated substitution by other protein sources. The relationship of overall and causes-specific mortality with red meat, processed meat, and other dietary protein sources was investigated in The Netherlands Cohort Study. In 1986, 120,852 men and women aged 55-69 years provided information on dietary and lifestyle habits. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-019-00483-9
Publisher Site
http://dx.doi.org/10.1007/s10654-019-00483-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451725PMC
April 2019
14 Reads

Intake of sucrose-sweetened soft beverages during pregnancy and risk of congenital heart defects (CHD) in offspring: a Norwegian pregnancy cohort study.

Eur J Epidemiol 2019 Apr 19;34(4):383-396. Epub 2019 Jan 19.

Department of Global Public Health and Primary Care, Faculty of Medicine, University of Bergen, Bergen, Norway.

Studies report increased risk of congenital heart defects (CHD) in the offspring of mothers with diabetes, where high blood glucose levels might confer the risk. We explored the association between intake of sucrose-sweetened soft beverages during pregnancy and risk of CHD. Prospective cohort data with 88,514 pregnant women participating in the Norwegian Mother and Child Cohort Study was linked with information on infant CHD diagnoses from national health registers and the Cardiovascular Diseases in Norway Project. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-019-00480-y
Publisher Site
http://dx.doi.org/10.1007/s10654-019-00480-yDOI Listing
April 2019
26 Reads

Hospitalisation of people with dementia: evidence from English electronic health records from 2008 to 2016.

Eur J Epidemiol 2019 Jan 16. Epub 2019 Jan 16.

Division of Psychiatry, University College London, 6th Floor, Maple House, 149 Tottenham Court Road, London, W1T 7NF, UK.

Hospitalisation of people with dementia is associated with adverse outcomes and high costs. We aimed to examine general, i.e. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-019-00481-x
Publisher Site
http://dx.doi.org/10.1007/s10654-019-00481-xDOI Listing
January 2019
18 Reads

Secular trends of mortality and dementia-free life expectancy over a 10-year period in France.

Eur J Epidemiol 2019 Feb 16;34(2):115-123. Epub 2019 Jan 16.

Université de Bordeaux, INSERM, Bordeaux Population Health Research Center, UMR1219, 33000, Bordeaux, France.

The aim of this paper was to investigate the evolution of mortality and life expectancy according to dementia in two French populations 10 years apart. Two different populations of subjects aged 65 or older included in PAQUID from 1988 to 1989 (n = 1342) and 3C from 1999 to 2000 (n = 1996) and initially not demented were followed over 10 years. Dementia was assessed using an algorithmic approach, and participants were considered to have dementia if they had an MMSE score < 24 AND a 4IADL score > 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-019-00482-wDOI Listing
February 2019
5 Reads

Causal criteria: time has come for a revision.

Eur J Epidemiol 2019 Jan 16. Epub 2019 Jan 16.

Department of Philosophy and History of Ideas, School of Culture and Society, Aarhus University, Building 1465, Jens Chr. Skous Vej 7, 8000, Aarhus C, Denmark.

Epidemiologists study associations but they are usually interested in causation that could lead to disease prevention. Experience show, however, that many of the associations we identify are not the causes we take an interest in (correlation is not causation). In order to proper translate association into causes, a set of causal criteria was developed 50-60 years ago and they became important tools guiding this translational process (sometimes correlation is causation). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-018-00479-xDOI Listing
January 2019
2 Reads

Alcohol consumption and labour market participation: a prospective cohort study of transitions between work, unemployment, sickness absence, and social benefits.

Eur J Epidemiol 2019 Apr 10;34(4):397-407. Epub 2019 Jan 10.

National Institute of Public Health, University of Southern Denmark, Studiestræde 6, 1455, Copenhagen, Denmark.

The aim of this study was to investigate the association of alcohol consumption and problem drinking on transitions between work, unemployment, sickness absence and social benefits. Participants were 86,417 men and women aged 18-60 years who participated in the Danish National Health Survey in 2010. Information on alcohol consumption (units per week) and problem drinking (CAGE-C score of 4-6) was obtained by questionnaire. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-018-0476-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451700PMC
April 2019
2 Reads

The risk of breast and gynecological cancer in women with a diagnosis of infertility: a nationwide population-based study.

Eur J Epidemiol 2019 May 9;34(5):499-507. Epub 2019 Jan 9.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Box 281, 171 77, Stockholm, Sweden.

Some studies have suggested that infertility is a risk factor for endometrial, ovarian and breast cancer. The study aimed to create a comprehensive picture of the association between infertility and the risk of ovarian, endometrial and breast cancer, and whether any association could be explained by ovulatory disturbances, endometriosis or nulliparity. In a population-based cohort of 2,882,847 women, cox regression analysis was used to investigate cancer incidence among infertile women. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-018-0474-9
Publisher Site
http://dx.doi.org/10.1007/s10654-018-0474-9DOI Listing
May 2019
17 Reads

Stem cell replication, somatic mutations and role of randomness in the development of cancer.

Eur J Epidemiol 2019 May 8;34(5):439-445. Epub 2019 Jan 8.

CESP (Inserm U1018), Facultés de Médicine Université Paris-Sud, UVSQ, Université Paris-Saclay, Gustave Roussy, 94805, Villejuif, France.

An intense scientific debate has recently taken place relating to the "bad luck" hypothesis in cancer development, namely that intrinsic random, and therefore unavoidable, mutagenic events would have a predominant role in tumorigenesis. In this article we review the main contributions to this debate and explain the reasons why the claim that cancer is mostly explained by intrinsic random factors is unsupported by data and theoretical models. In support of this, we present an analysis showing that smoking-induced mutations are more predictive of cancer risk than the lifetime number of stem cell cellular divisions. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-018-0477-6
Publisher Site
http://dx.doi.org/10.1007/s10654-018-0477-6DOI Listing
May 2019
18 Reads

Vision loss and 12-year risk of dementia in older adults: the 3C cohort study.

Eur J Epidemiol 2019 Feb 4;34(2):141-152. Epub 2019 Jan 4.

Inserm, Bordeaux Population Health Research Center, UMR 1219, Univ. Bordeaux, 33000, Bordeaux, France.

To analyze the longitudinal relationships between vision loss and the risk of dementia in the first 2 years, from 2 to 4 years and beyond 4 years after inclusion and to determine the roles of depressive symptomatology and engagement in cognitively stimulating activities in these associations. This study is based on the Three-City (3C) study, a population-based cohort of 7736 initially dementia-free participants aged 65 years and over with 12 years of follow-up. Near visual impairment (VI) was measured and distance visual function (VF) loss was self-reported. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-018-00478-y
Publisher Site
http://dx.doi.org/10.1007/s10654-018-00478-yDOI Listing
February 2019
17 Reads

Protein markers and risk of type 2 diabetes and prediabetes: a targeted proteomics approach in the KORA F4/FF4 study.

Eur J Epidemiol 2019 Apr 31;34(4):409-422. Epub 2018 Dec 31.

Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health (GmbH), Ingolstädter Landstraße 1, 85764, Neuherberg, Germany.

The objective of the present study was to identify proteins that contribute to pathophysiology and allow prediction of incident type 2 diabetes or incident prediabetes. We quantified 14 candidate proteins using targeted mass spectrometry in plasma samples of the prospective, population-based German KORA F4/FF4 study (6.5-year follow-up). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-018-0475-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451724PMC
April 2019
3 Reads

The neutrophil-to-lymphocyte ratio is associated with mortality in the general population: The Rotterdam Study.

Eur J Epidemiol 2019 May 19;34(5):463-470. Epub 2018 Dec 19.

Department of Epidemiology, Erasmus MC University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

Inflammation is a risk factor for morbidity and mortality in the elderly. The neutrophil-to-lymphocyte ratio (NLR) is a marker of systemic inflammation that integrates the information of the leukocyte differentials into one variable. We aimed to assess whether the NLR is a risk indicator for overall and cause-specific mortality in the general population. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-018-0472-y
Publisher Site
http://dx.doi.org/10.1007/s10654-018-0472-yDOI Listing
May 2019
6 Reads

Cardiovascular mortality attributable to dietary risk factors in 51 countries in the WHO European Region from 1990 to 2016: a systematic analysis of the Global Burden of Disease Study.

Eur J Epidemiol 2019 Jan 14;34(1):37-55. Epub 2018 Dec 14.

Competence Cluster for Nutrition and Cardiovascular Health (nutriCARD), Halle-Jena-Leipzig, Germany.

This study was performed to highlight the relationship between single dietary risk factors and cardiovascular diseases (CVDs) in the WHO European Region. We used the comparative risk assessment framework of the Global Burden of Disease Study to estimate CVD mortality attributable to diet; comprising eleven forms of CVDs, twelve food and nutrient groups and 27 risk-outcome pairs in four GBD regions including 51 countries by age and sex between 1990 and 2016. In 2016, dietary risks were associated with 2. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-018-0473-x
Publisher Site
http://dx.doi.org/10.1007/s10654-018-0473-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325999PMC
January 2019
16 Reads

Hypothesis: ubiquitous circadian disruption can cause cancer.

Eur J Epidemiol 2019 Jan 13;34(1):1-4. Epub 2018 Dec 13.

Institute and Policlinic for Occupational Medicine, Environmental Medicine and Prevention Research, University Hospital of Cologne, Cologne, Germany.

Circadian disruption (CD) was implicated in chains of cancer causation when the International Agency for Research on Cancer classified shift-work involving circadian disruption as probably carcinogenic in 2007. In the following decade, epidemiological studies into causal concepts associated with circadian disruption were inconclusive. Unappreciated complexity with an exclusive focus on shift-work, light-at-night, sleep, and melatonin in regard to circadian disruption may be accountable. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-018-0469-6
Publisher Site
http://dx.doi.org/10.1007/s10654-018-0469-6DOI Listing
January 2019
32 Reads

The Apgar paradox.

Eur J Epidemiol 2019 Feb;34(2):103-104

Department of Social and Behavioral Science, Harvard TH Chan School of Public Health, Boston, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-018-0466-9
Publisher Site
http://dx.doi.org/10.1007/s10654-018-0466-9DOI Listing
February 2019
10 Reads

Contribution of the OC Sensor immunoassay in comparison to the Hemoccult II guaiac-test in organized colorectal cancer screening.

Eur J Epidemiol 2019 Feb 8;34(2):163-172. Epub 2018 Dec 8.

Service d'Hépato-gastro-entérologie, CHU Angers, 4, rue Larrey, 49933, Angers Cedex 09, France.

Colorectal cancer (CRC) is a major cause of cancer-related death of worldwide with high incidence and mortality rate, accessible to a screening program in France, first with guaiac- based fecal occult blood test (g-FOBT) then with fecal immunochemical tests (FIT), since 2015, because of better accuracy. The aim of our study was to compare the characteristics of screen-detected lesions in two successive CRC screening campaigns, using two different tests (Hemoccult II and OC Sensor) in the department of Maine-et-Loire, and to precise the performance of these tests [participation rate, detection rates (DR), positive predictive value (PPV)]. Participants, invited by CAP SANTE 49, with polyps or cancer at the colonoscopy after a positive screening test between 01/01/2013 and 31/12/2016 were included. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10654-018-0471-zDOI Listing
February 2019
2 Reads

A note of thanks and an invitation.

Authors:
Albert Hofman

Eur J Epidemiol 2018 Dec;33(12):1131-1133

, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s10654-018-0464-y
Publisher Site
http://dx.doi.org/10.1007/s10654-018-0464-yDOI Listing
December 2018
16 Reads