4,468 results match your criteria European Journal of Dermatology[Journal]


How will clinical practice be impacted by artificial intelligence?

Authors:
Jacques Biot

Eur J Dermatol 2019 Apr;29(S1):8-10

École des Mînes, 60, boulevard Saint-Michel, 75006 Paris, France.

Currently, artificial intelligence (AI) heavily impacts all human activities, including medicine, where needs for data analysis and interpretation are high and where technology opens new perspectives. Considering that current treatments do not always cure all patients and may even harm certain of them, we have to recognize that AI may fill a great medical need, potentially supporting physicians' efforts to refine diagnosis and to improve the relevance of the clinical diagnosis for each patient. As in other industries, this challenge implies changes in the repartition of medical and paramedical tasks. Read More

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http://dx.doi.org/10.1684/ejd.2019.3536DOI Listing

Computational neural network in melanocytic lesions diagnosis: artificial intelligence to improve diagnosis in dermatology?

Eur J Dermatol 2019 Apr;29(S1):4-7

Facolta di Medicina et Chirugia, UNIMORE Iniversita Degli Studi di Modena e Reggio Emilia, Modena, Italy.

Diagnosis in dermatology is largely based on contextual factors going far beyond the visual and dermoscopic inspection of a lesion. Diagnostic tools such as the different types of dermoscopy, confocal microscopy and optical coherence tomography (OCT) are available and all of these have shown their importance in improving the dermatologist's ability, especially in the diagnosis of skin cancer. Their use, however, remains limited and time consuming, and optimizing their practice appears to be difficult, requiring extensive pre-processing, lesion segmentation and extraction of domain-specific visual features before classification. Read More

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http://dx.doi.org/10.1684/ejd.2019.3538DOI Listing

Highlights from the 5th World Rendezvous on Dermatology in Rio de Janeiro on 2nd and 3rd November 2018, under the aegis of the Fondation Bioderma.

Authors:
Carle Paul

Eur J Dermatol 2019 Apr;29(S1)

Dermatology, hôpital Larrey, Toulouse University, 31059 Toulouse, France.

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http://dx.doi.org/10.1684/ejd.2019.3537DOI Listing

Fondation BIODERMA Moving Dermatology Forward, Improving Patients' Opportunities Around the World.

Authors:
Corinne Minmin

Eur J Dermatol 2019 Apr;29(S1)

General Secretary, Fondation Bioderma.

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http://dx.doi.org/10.1684/ejd.2019.3540DOI Listing

The microbiome, a new target for ecobiology in dermatology.

Authors:
Brigitte Dréno

Eur J Dermatol 2019 Apr;29(S1):15-18

CHU Nantes-Hôtel-Dieu, UF dermato-cancérologie, Inserm U1232, CIC biothérapie Inserm 05031, place Alexis-Ricordeau, 44093 Nantes cedex 01, France.

The skin is the human body's largest organ colonised by a large community of microorganisms. The ecological community of microorganisms that are present on our body and of the body itself defines the human skin microbiome. Ecobiology is a new scientific approach that is based on the principle that the skin is an ever-evolving ecosystem which interacts with its environment and whose natural resources and mechanisms must be preserved. Read More

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http://dx.doi.org/10.1684/ejd.2019.3535DOI Listing

Ecobiological approach to research regarding ageing and diseases.

Authors:
Miroslav Radman

Eur J Dermatol 2019 Apr;29(S1):11-14

Mediterranean Institute for Life Sciences, Split, Croatia, Naos Institute for Life Sciences, Aix-en-Provence, France, Université R.-Descartes Paris-5, faculté de médecine, INSERM U1001, Paris, France.

Ageing and age-related diseases (ARD) share a common biological clock that appears as their root cause: protein damage. A majority of proteins have evolved into native structures resistant to oxidative damage but any folding imperfections, including those due to "silent" amino acid substitutions, reduce oxidation resistance. Damaged proteins accumulate with age and trigger ageing-like phenotypes reversible by their turnover, while acquired genome alterations remain as stable consequences of protein malfunction. Read More

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http://dx.doi.org/10.1684/ejd.2019.3534DOI Listing

Imiquimod-induced widespread psoriasiform eruptions.

Eur J Dermatol 2019 Apr 23. Epub 2019 Apr 23.

Department of Dermatology, Fukushima Medical University, Fukushima, Japan.

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http://dx.doi.org/10.1684/ejd.2019.3517DOI Listing

Fibroblast and keratinocyte crosstalk: the effect of a poly(tri[ethylene glycol] ethyl ether methacrylate) thermoresponsive surface on short-term co-culture.

Eur J Dermatol 2019 Apr 23. Epub 2019 Apr 23.

Department of Katowice, Medyków 18 str, Bldg. C-1, 40-752 Katowice,, Centre for Burn Treatment in Siemianowice Śląskie, Siemianowice Śląskie Jana Pawla II.

The treatment of difficult-to-treat wounds can be challenging. Although a number of approaches have been investigated, the healing process may be slow and unsatisfactory. An alternative approach is the use of a continuous sheet of skin cells applied over a wound which may improve cell implantation and patient recovery. Read More

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http://dx.doi.org/10.1684/ejd.2019.3561DOI Listing
April 2019
1 Read

Rare CARD14 missense variants associated with palmoplantar pustulosis (PPP) in the Chinese Han population.

Eur J Dermatol 2019 Feb;29(1):99-100

Shandong University, Shandong Provincial Hospital for Skin Disease, Department of Dermatology,, Shandong Provincial Institute of Dermatology and Venereology, Shandong Academy of Medical Sciences,, Shandong Provincial Key Lab for Dermatovenereology, Jinan, Shandong 250022, China.

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http://dx.doi.org/10.1684/ejd.2018.3457DOI Listing
February 2019

Varicella complicated by necrotizing soft tissue infection in childhood: an argument for systematic childhood varicella vaccination in France?

Eur J Dermatol 2019 Feb;29(1):91-93

CHU of Clermont-Ferrand, Estaing Hospital, Oral and Maxillofacial Department, 1, place Lucie-Aubrac, 63003 Clermont-Ferrand cedex 1, France, University of Auvergne, Faculty of Medicine, 28, place Henri-Dunant, BP 38, 63001 Clermont-Ferrand cedex 1, France, University of Lille Nord de France, UMR Inserm U1008, Controlled Drug Delivery Systems and Biomaterials, 59000 Lille, France.

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http://dx.doi.org/10.1684/ejd.2018.3462DOI Listing
February 2019

Muehrcke lines on fingers and toenails.

Eur J Dermatol 2019 Feb;29(1):87-88

Division of Dermatology, Tohoku Medical and Pharmaceutical University, 1-15-1 Fukumuro, Miyagino-ku, Sendai 983-8536, Japan.

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http://dx.doi.org/10.1684/ejd.2018.3439DOI Listing
February 2019

Hydroa vacciniforme: a distinctive form of Epstein-Barr virus-associated T-cell lymphoproliferative disorders.

Eur J Dermatol 2019 Feb;29(1):21-28

Department of Dermatology, Kawasaki Medical School,, Department of Dermatology, Kawasaki Medical School General Medical Center, Okayama, Japan.

Hydroa vacciniforme (HV) is a cutaneous subset of Epstein-Barr virus (EBV)-associated T/NK lymphoproliferative disorders (LPDs). Our previous case series study clearly showed a clinical spectrum of EBV-associated T/NK LPDs including HV, hypersensitivity to mosquito bites (HMB), chronic active EBV infection (CAEBV), and hemophagocytic lymphohistiocytosis (HLH). Patients with HV are divided into two groups: a benign subtype designated "classic HV" (cHV) and more serious systemic HV (sHV), also called "HV-like LPD" in the 2017 World Health Organization (WHO) classification. Read More

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http://dx.doi.org/10.1684/ejd.2018.3490DOI Listing
February 2019

Erratum.

Authors:

Eur J Dermatol 2019 Feb;29(1):112

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http://dx.doi.org/10.1684/ejd.2019.3508DOI Listing
February 2019

sQUIZ your knowledge: Multiple waxy yellow nodules on the leg.

Eur J Dermatol 2019 Feb;29(1):111-112

Department of Dermatology and Venereology, Peking University First Hospital Peking University First Hospital, Beijing, China.

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http://dx.doi.org/10.1684/ejd.2019.3514DOI Listing
February 2019

A large nodule on the scalp of an Indian female.

Eur J Dermatol 2019 Feb;29(1):110

Department of Dermatology, Royal London Hospital, Whitechapel, London, UK.

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http://dx.doi.org/10.1684/ejd.2019.3513DOI Listing
February 2019

"Knife-cut" ulcers in intertriginous areas.

Eur J Dermatol 2019 Feb;29(1):109-110

Department of Dermatology, Hospital Universitario de Fuenlabrada, Madrid, Spain.

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http://dx.doi.org/10.1684/ejd.2019.3512DOI Listing
February 2019

Erythema multiforme-like rash upon anti-melanoma therapy with BRAF and MEK inhibitors.

Eur J Dermatol 2019 Feb;29(1):107-108

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1684/ejd.2019.3511DOI Listing
February 2019

Dermpath and Clinic: Chronic scaly papules on the back and lower extremities.

Eur J Dermatol 2019 Feb;29(1):106-107

Department of Dermatology, Hospital General Universitario Gregorio Marañón, Madrid.

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http://dx.doi.org/10.1684/ejd.2019.3510DOI Listing
February 2019

What's new this month?

Eur J Dermatol 2019 Feb;29(1):105-106

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1684/ejd.2019.3509DOI Listing
February 2019
1 Read

Heat shock proteins and psoriasis.

Eur J Dermatol 2019 Apr 17. Epub 2019 Apr 17.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaArticle accepted on October 23, 2018.

Psoriasis is a chronic disfiguring skin condition which may be induced or exacerbated by stress. Heat shock proteins (HSPs), as molecular chaperones, play a central role in protein folding and cellular protein homeostasis. The many different functions of HSPs in the cell depend on the specific HSP involved. Read More

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http://dx.doi.org/10.1684/ejd.2019.3526DOI Listing
April 2019
1 Read

Staging of primary cutaneous follicle centre B-cell lymphoma: bone marrow biopsy, CD10, BCL2 and t(14;18) are not relevant prognostic factors.

Eur J Dermatol 2019 Apr 17. Epub 2019 Apr 17.

Dermatologie, Institut Universitaire du Cancer de Toulouse, Université Paul Sabatier, Hôpital Larrey et Oncopole, Toulouse.

Background: There is a certain degree of controversy as to whether bone marrow biopsy is required during the staging procedures for primary cutaneous follicle centre B-cell lymphoma (PCFCCL).

Objectives: Firstly, to determine extra-cutaneous involvement at initial diagnosis, in particular, based on bone marrow biopsy, and secondly, evaluate the phenotypic features associated with extra-cutaneous involvement during follow-up (in particular, the predictive value of BCL2 and CD10 coexpression and identification of t[14;18] in skin lesions, as well as bone marrow biopsy involvement at initial staging) in a cohort of patients with PCFCCL.

Materials & Methods: A bicentric retrospective study was established to investigate 75 cases of PCFCCL, for which 44 bone marrow biopsies were performed. Read More

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http://dx.doi.org/10.1684/ejd.2018.3489DOI Listing
April 2019
2 Reads

Postherpetic hypohidrosis-related isotopic response associated with lichen planus and lichen amyloidosis.

Eur J Dermatol 2019 Apr 12. Epub 2019 Apr 12.

Department of dermatology, Kawasaki Medical School, Kurashiki.

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http://dx.doi.org/10.1684/ejd.2019.3516DOI Listing
April 2019
2 Reads

Pemphigus vegetans initiating on the finger and nail.

Eur J Dermatol 2019 Apr 12. Epub 2019 Apr 12.

Department of Dermatology, Eberhard-Karls-University, Liebermeisterstrasse 25, D-72076 Tübingen, Germany.

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http://dx.doi.org/10.1684/ejd.2018.3407DOI Listing
April 2019
1 Read

Health-related quality of life associated with immunocryosurgery, a minimally invasive modality, for cervicofacial basal cell carcinoma.

Eur J Dermatol 2019 Apr 10. Epub 2019 Apr 10.

Department of Skin and Venereal Diseases, Faculty of Medicine, School of Health Sciences, University of Ioannina, Ioannina, Greece.

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http://dx.doi.org/10.1684/ejd.2019.3521DOI Listing

Possible involvement of IgE antibody in epidermolysis bullosa acquisita: detection and correlation.

Eur J Dermatol 2019 Apr 10. Epub 2019 Apr 10.

Department of Dermatology, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.1684/ejd.2019.3497DOI Listing

Penile terra firma-forme dermatosis in a child: ultrastructural observation and topical ethacridine lactate and tacrolimus treatment.

Eur J Dermatol 2019 Apr 10. Epub 2019 Apr 10.

Department of Dermatology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.

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http://dx.doi.org/10.1684/ejd.2019.3505DOI Listing

Targeted therapies and precision medicine for inflammatory skin diseases.

Authors:
Michel Gilliet

Eur J Dermatol 2019 Apr;29(S1):19-24

Department of Dermatology, University Hospital CHUV, Lausanne, Switzerland.

Over the last years, several immune pathways in the skin have been identified. These discoveries have been translated into targeted therapies for inflammatory skin diseases, which have revolutionized our clinical practice. The perturbed molecular network in the skin may serve as a biomarker for disease prediction and as a source of targets for early therapeutic intervention or prevention. Read More

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http://dx.doi.org/10.1684/ejd.2019.3539DOI Listing
April 2019
5 Reads

Telangiectasia macularis eruptiva perstans: a neglected type of mastocytosis with exclusively cutaneous involvement? A case series.

Eur J Dermatol 2019 Apr 10. Epub 2019 Apr 10.

Institute of Dermatology Department of Clinical-Surgical, Diagnostic and Paediatric Sciences, Fondazione IRCCS Policlinico San Matteo, University of Pavia, Pavia, Italy.

Telangiectasia macularis eruptiva perstans (TMEP) is a rare form of cutaneous mastocytosis (CM). Although TMEP has been traditionally thought to be restricted to the skin, a recent retrospective multicentric study established a diagnosis with systemic involvement of mastocytosis in 47% patients affected by TMEP and aggressive systemic mastocytosis in 9%. To evaluate systemic involvement in patients affected by TMEP. Read More

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http://dx.doi.org/10.1684/ejd.2019.3532DOI Listing
April 2019
1 Read

Erythrodermic linear IgA/IgG bullous dermatosis.

Eur J Dermatol 2019 Apr 10. Epub 2019 Apr 10.

Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Abeno-ku, Osaka 545-8585, Japan.

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http://dx.doi.org/10.1684/ejd.2019.3503DOI Listing

Cutaneous vasculitis in HIV-associated Castleman's disease: a rare manifestation.

Eur J Dermatol 2019 Apr 10. Epub 2019 Apr 10.

Department of Dermatology and Venereology, HIV Unit, "Andreas Sygros" Hospital, 5 Dragoumi str. 16121 Athens, Greece.

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http://dx.doi.org/10.1684/ejd.2019.3520DOI Listing
April 2019
1 Read
1.990 Impact Factor

Prevalence of cutaneous comorbidities in psoriatic patients and their impact on quality of life.

Eur J Dermatol 2019 Apr 10. Epub 2019 Apr 10.

Dermatology Department, Catholic University of the Sacred Heart, Rome.

In contrast to the evidence for systemic co-morbidities, relatively few studies have examined the prevalence of cutaneous inflammatory co-morbidities in psoriatic patients. We conducted an observational multi-site study to measure the prevalence of cutaneous co-morbidities in adult patients with plaque psoriasis and to assess the relative impact on quality of life (QOL). Each patient attending one of the study clinics over a period of six months was evaluated to assess the presence of any concomitant skin inflammatory disease other than psoriasis at the time of the visit. Read More

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http://dx.doi.org/10.1684/ejd.2019.3529DOI Listing
April 2019
2 Reads

Clinical and dermoscopic (in vivo and ex vivo) predictors of recurrent nevi.

Eur J Dermatol 2019 Mar 25. Epub 2019 Mar 25.

Department of Dermatology, Hospital de Clínicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, Brazil.

Recurrent nevi occur following removal of melanocytic nevi mainly after shaving excision. Due to its differential diagnosis with melanoma, its recognition can be challenging. To evaluate clinical and dermoscopic predictors of recurrent nevi. Read More

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http://dx.doi.org/10.1684/ejd.2019.3530DOI Listing
March 2019
1 Read

Effectiveness of psychological intervention in psoriatic patients relative to standard care.

Eur J Dermatol 2019 Mar 25. Epub 2019 Mar 25.

Department of Experimental, Diagnostic and Specialty Medicine, Division of Dermatology, S. Orsola-Malpighi Hospital, University of Bologna.

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http://dx.doi.org/10.1684/ejd.2019.3515DOI Listing

DNA damage in human skin fibroblasts from patients with dermatitis herpetiformis

Eur J Dermatol 2019 03 11. Epub 2019 Mar 11.

Department of Biomedical, Surgical and Dental Sciences, Università degli Studi di Milano,, Center for Prevention and Diagnosis of Celiac Disease, Gastroenterology and Endoscopy Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico,, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, 20122 Milan, Italy.

Dermatitis herpetiformis (DH) and celiac disease (CD) are considered to be autoimmune diseases that share a specific trigger (gluten) and a common genetic background (HLA-DQ2/DQ8). However, the pathogenesis of DH is not yet fully understood and no data are available regarding a possible role of fibroblasts in this disease. The aim of this study was to assess baseline DNA damage in fibroblasts in DH-diagnosed patients vs. Read More

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http://dx.doi.org/10.1684/ejd.2019.3528DOI Listing
March 2019
8 Reads

Coexistence of anti-topoisomerase I and anti-RNA polymerase III antibody in a patient with overlap syndrome.

Eur J Dermatol 2019 Feb;29(1):93-94

Department of Dermatology, Faculty of Medicine, University of Yamanashi, Yamanashi.

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http://dx.doi.org/10.1684/ejd.2018.3475DOI Listing
February 2019

Corticosteroid-resistant prurigo nodularis: a rare syringotropic variant associated with hypohidrosis.

Eur J Dermatol 2019 Mar 2. Epub 2019 Mar 2.

Department of dermatology, Kawasaki Medical School, Kurashiki.

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http://dx.doi.org/10.1684/ejd.2019.3498DOI Listing
March 2019
2 Reads

Efficacy and safety of oral alitretinoin as treatment for chronic hand eczema in France: a real-life open-label study.

Eur J Dermatol 2019 Feb;29(1):59-66

Hôpital Henri Mondor, Dermatologie, Créteil, France.

Background: Chronic hand eczema is an inflammatory dermatosis that results in a significant psychological and socio-economic burden. Alitretinoin (AL) is indicated in adults with severe chronic hand eczema (sCHE) unresponsive to potent topical corticosteroids.

Objectives: To assess AL effectiveness and safety in patients with sCHE under real-life conditions based on a prospective observational study in France (2010-2014). Read More

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http://dx.doi.org/10.1684/ejd.2018.3484DOI Listing
February 2019
7 Reads

Papular nevus spilus syndrome: old and new aspects of a mosaic RASopathy.

Eur J Dermatol 2019 Feb;29(1):2-5

Department of Dermatology, Medical Center-University of Freiburg, Hauptstr 7, 79104 Freiburg, Germany.

The co-existence of papular nevus spilus (PNS) and ipsilateral extracutaneous abnormalities involving peripheral nerves of the skin or muscles was originally described as "speckled lentiginous nevus syndrome". To avoid confusion with macular nevus spilus, the condition was recently re-named "papular nevus spilus syndrome". In addition to 14 published cases, we identified six new cases via a search of the worldwide literature. Read More

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http://dx.doi.org/10.1684/ejd.2018.3488DOI Listing
February 2019
2 Reads

Hereditary angioedema: a Chinese perspective.

Eur J Dermatol 2019 Feb;29(1):14-20

Department of Allergy, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College.

Hereditary angioedema (HAE) is a rare autosomal dominant disorder of vascular permeability associated with heterogeneous clinical manifestations, with prevalence estimated at 1/50,000. Most disease-causing variants lie within the SERPING1 gene, while FXII12, PLG and ANGPT1 gene variants are also reported to associate with HAE. Research on HAE in China began in the 1980s, and later studies identified some clinical characteristics of Chinese HAE patients that differ from the western population. Read More

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http://dx.doi.org/10.1684/ejd.2018.3487DOI Listing
February 2019
15 Reads

Characterisation of the circular RNA landscape in mesenchymal stem cells from psoriatic skin lesions.

Eur J Dermatol 2019 Feb;29(1):29-38

1Institute of Dermatology, Taiyuan City Centre Hospital, Shanxi Key Laboratory of Stem Cells for Immunological Dermatosis, No. 1 Dong San Dao Xiang, Taiyuan, Shanxi Province 030009, China.

Circular RNAs (circRNAs) have recently emerged as novel non-coding regulatory RNAs, reportedly involved in many biological processes and human diseases. However, the role of circRNAs in the pathogenesis of psoriasis is unclear. Additionally, mesenchymal stem cells (MSCs) are involved in pathological processes associated with immune diseases, including psoriasis. Read More

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http://dx.doi.org/10.1684/ejd.2018.3483DOI Listing
February 2019
1 Read

Successful treatment of TNFα inhibitor-resistant pityriasis rubra pilaris with ixekizumab and acitretin.

Eur J Dermatol 2019 Mar 2. Epub 2019 Mar 2.

Department of Dermatology, Edouard-Herriot Hospital, Lyon I University, Lyon, France.

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http://dx.doi.org/10.1684/ejd.2019.3502DOI Listing
March 2019
1 Read

Dramatic exacerbation of bullous pemphigoid following rituximab and successful treatment with omalizumab.

Eur J Dermatol 2019 Mar 2. Epub 2019 Mar 2.

Section of Dermatology, Department of Surgery and Translational Medicine, University of Florence, Florence Italy.

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http://dx.doi.org/10.1684/ejd.2019.3499DOI Listing

Daylight photodynamic therapy for severe facial and scalp actinic keratosis: a prospective non-sponsored single-centre study employing the actinic keratosis area and severity index (AKASI).

Eur J Dermatol 2019 Feb;29(1):67-74

Department of Dermatology, Eberhard Karls University, Liebermeisterstr. 25, D-72076 Tübingen, Germany.

Daylight photodynamic therapy (DL-PDT) is an effective and convenient treatment for multiple actinic keratosis (AKs). There are limited tools to evaluate the outcome of AK treatment. Recently, the actinic keratosis area and severity index (AKASI) has been proposed as a quantitative tool for assessing AK severity. Read More

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http://dx.doi.org/10.1684/ejd.2018.3492DOI Listing
February 2019

The burden of chronic urticaria: French baseline data from the international real-life AWARE study.

Eur J Dermatol 2019 Feb;29(1):49-54

Dermatology Department, Larrey Hospital, CHU Toulouse, Toulouse, France.

Background: The AWARE study is an ongoing international study of patients with chronic urticaria refractory to H1-antihistamines. The aim of this study is to evaluate the burden of disease and the use of healthcare resources in real-life conditions.

Objectives: To analyse the baseline data of French patients included in the AWARE study. Read More

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http://dx.doi.org/10.1684/ejd.2018.3495DOI Listing
February 2019
2 Reads