6,411 results match your criteria European Journal of Clinical Nutrition [Journal]


Ultrasound and MRI measured changes in muscle mass gives different estimates but similar conclusions: a Bayesian approach.

Eur J Clin Nutr 2019 Apr 23. Epub 2019 Apr 23.

School of Nursing, Seirei Christopher University, Shizuoka, Japan.

The purpose of this paper was to use a Bayesian approach to compare the relative change in muscle size between magnetic resonance imaging (MRI) and ultrasound measured muscle thickness (MTH) following 6 weeks of concentric and eccentric blood flow restricted exercise. Changes at each site were as follows: concentric 50% site (MRI: 10.2%, MTH: 8. Read More

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http://dx.doi.org/10.1038/s41430-019-0431-zDOI Listing

Glycemic response to low sugar apple juice treated with invertase, glucose oxidase and catalase.

Eur J Clin Nutr 2019 Apr 10. Epub 2019 Apr 10.

CRC Clinical Research Center Kiel, Kiel Center of Innovation and Technology, Kiel, Germany.

Background/objectives: Investigating the effect on post-prandial glycemic and venous serum insulin response of an apple drink following the conversion of its glucose to gluconate.

Subjects/methods: In a double-blind randomized placebo-controlled clinical trial with cross-over design, 30 male adults with impaired fasting glucose (IFG) received a drink of 500 ml: 1. Verum: Apple juice treated with invertase, glucose oxidase/catalase (glucose 0. Read More

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http://www.nature.com/articles/s41430-019-0421-1
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http://dx.doi.org/10.1038/s41430-019-0421-1DOI Listing
April 2019
1 Read

Weight loss at your fingertips: personalized nutrition with fasting glucose and insulin using a novel statistical approach.

Eur J Clin Nutr 2019 Apr 9. Epub 2019 Apr 9.

Department of Nutrition, Exercise and Sports, Faculty of Sciences, University of Copenhagen, Copenhagen, Denmark.

Background/objectives: Precision medicine is changing the way people are diagnosed and treated into a more personalized approach. Using a novel statistical approach, we demonstrate how two diets cause differential weight loss depending on pre-treatment fasting plasma glucose (FPG) and fasting insulin (FI) levels.

Subjects/methods: One hundred and eighty-one overweight people with increased waist circumference were randomly assigned to receive an ad libitum New Nordic Diet (NND) high in dietary fiber and whole grain or an Average Danish (Western) Diet (ADD) for 26 weeks. Read More

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http://dx.doi.org/10.1038/s41430-019-0423-zDOI Listing

The association of lecithin retinol acyltransferase and the 25(OH)D receptor with pediatric overweight and obesity.

Eur J Clin Nutr 2019 Apr 9. Epub 2019 Apr 9.

Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Paediatrics in Chongqing, China International Science and Technology Cooperation base of Child Development and Critical Disorders, Chongqing, China.

The aim of this study is to determine whether lecithin retinol acyltransferase (LRAT) as well as biomarkers of vitamin A (VA) and vitamin D are related to indices of obesity in childhood. A total of 164 children (aged 6-12 years, female 49.39%), comprising 66 children in the overweight/obese group and 98 children in the lean group, were included. Read More

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http://dx.doi.org/10.1038/s41430-019-0422-0DOI Listing

Effect of early enteral nutrition on laparoscopic common bile duct exploration with enhanced recovery after surgery protocols.

Eur J Clin Nutr 2019 Apr 9. Epub 2019 Apr 9.

Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, USA.

Background/objectives: Protocols for enhanced recovery after surgery (ERAS) provide comprehensive and evidence-based guidelines to improve perioperative care. It remains elusive whether early enteral nutrition (EEN) will play an active role in the ERAS protocols. Laparoscopic common bile duct exploration (LCBDE) is a safe and efficient method to treat patients with bile duct stones. Read More

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http://dx.doi.org/10.1038/s41430-019-0425-xDOI Listing

Relationship between carbohydrate and dietary fibre intake and the risk of cardiovascular disease mortality in Japanese: 24-year follow-up of NIPPON DATA80.

Eur J Clin Nutr 2019 Apr 8. Epub 2019 Apr 8.

Department of Public Health, Shiga University of Medical Science, Otsu, 520-2192, Japan.

Background/objectives: The association between carbohydrate intake and cardiovascular disease (CVD) risk has been investigated, but whether the quality of carbohydrate is more important than its amount is not known. We examined the associations between intake of dietary fibre (DF), carbohydrate, available carbohydrate, and starch with long-term CVD mortality in a Japanese population.

Subjects/methods: We prospectively followed 8925 participants (3916 men and 5009 women) aged 30-79 years without CVD at baseline who participated in the National Nutrition Survey in Japan. Read More

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http://dx.doi.org/10.1038/s41430-019-0424-yDOI Listing

Sulfite concentration and the occurrence of headache in young adults: a prospective study.

Eur J Clin Nutr 2019 Apr 8. Epub 2019 Apr 8.

Faculty of Health Sciences, University of Beira Interior, Covilhã, Portugal.

Background/objectives: Sulfites are additives commonly used in food and wine industries that are associated to adverse clinical effects such as headaches. The objective of this study is to investigate the possible association between sulfite concentration in wine and the occurrence of headaches in young adults.

Subjects/methods: Eighty volunteers, aged between 18 and 25 years, were evaluated. Read More

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http://www.nature.com/articles/s41430-019-0420-2
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http://dx.doi.org/10.1038/s41430-019-0420-2DOI Listing
April 2019
2 Reads

Reviewer recognition.

Authors:

Eur J Clin Nutr 2019 Apr;73(4):642-644

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http://dx.doi.org/10.1038/s41430-019-0412-2DOI Listing

Comparison of multifrequency bioimpedance measured lean mass to that calculated from anthropomometric measurements in patients with chronic kidney disease.

Eur J Clin Nutr 2019 Mar 29. Epub 2019 Mar 29.

UCL Department of Nephrology, Royal Free Hospital, University College London, London, NW3 2PF, UK.

Patients with chronic kidney disease (CKD) are at increased risk of sarcopenia. Previous studies have proposed equations to estimate muscle mass based on triceps skin-fold thickness and mid-upper arm circumference, with or without adjustment for hand grip strength (HGS). We wished to evaluate their usefulness compared to multifrequency segmental bioimpedance (MFBIA) measured appendicular lean mass (ALM). Read More

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http://dx.doi.org/10.1038/s41430-019-0415-zDOI Listing
March 2019
1 Read

Association of dietary diversity with total mortality and major causes of mortality in the Japanese population: JPHC study.

Eur J Clin Nutr 2019 Mar 19. Epub 2019 Mar 19.

Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.

Background/objectives: Eating a variety of foods has been recommended in the dietary guidelines of many developed nations, as well as global dietary guidelines. We investigated the potential effect of dietary diversity on the risk of total mortality and major causes of mortality in a large-scale cohort study involving the Japanese population.

Subjects/methods: From 1995 to 2012, 79,904 participants (37,240 men and 42,664 women) aged 45 to 74 years, without histories of ischemic heart disease, stroke, or cancer were followed-up for a median of 14. Read More

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http://dx.doi.org/10.1038/s41430-019-0416-yDOI Listing

Body composition and nutritional status in malignant pleural mesothelioma: implications for activity levels and quality of life.

Eur J Clin Nutr 2019 Mar 18. Epub 2019 Mar 18.

Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.

Background/objectives: Malignant pleural mesothelioma (MPM) is an incurable cancer and optimizing daily physical activity and quality of life are key goals of patient management. Little is known about the prevalence of pre-sarcopenia and malnutrition in MPM or their associations with patient outcomes. This study aimed to determine the prevalence of pre-sarcopenia and malnutrition in MPM and investigate if activity levels and quality of life differed according to body composition and nutritional status. Read More

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http://dx.doi.org/10.1038/s41430-019-0418-9DOI Listing
March 2019
1 Read

A systematic review and meta-analysis of the response of serum 25-hydroxyvitamin D concentration to vitamin D supplementation from RCTs from around the globe.

Eur J Clin Nutr 2019 Mar 14. Epub 2019 Mar 14.

Department of Public Health, and Department of Anesthesiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

Background/objectives: Optimal doses of vitamin D (VitD) supplement in different populations are unclear. We aim to evaluate the relationship between VitD supplementation and post-intervention serum 25-hydroxyvitamin D [25(OH)D] concentration, to provide a recommended dosage of VitD for achieving an optimal 25(OH)D concentration for different populations.

Subjects/methods: Literature search was conducted in Embase, etc. Read More

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http://dx.doi.org/10.1038/s41430-019-0417-xDOI Listing
March 2019
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Relationship between computed tomography-derived body composition, sex, and post-operative complications in patients with colorectal cancer.

Eur J Clin Nutr 2019 Mar 11. Epub 2019 Mar 11.

Academic Unit of Surgery, College of Medical, Veterinary and Life of Sciences, Royal Infirmary, University of Glasgow, Glasgow, G31 2ER, Scotland.

Introduction: In the UK, colorectal cancer is the fourth most common cancer and the second most common cause of cancer death. Surgery is the primary modality of treatment, but it is not without complications. Post-operative complications have been linked to preoperative of weight loss and loss of lean tissue, and also to obesity. Read More

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http://dx.doi.org/10.1038/s41430-019-0414-0DOI Listing

SCREEN III: working towards a condensed screening tool to detect nutrition risk in community-dwelling older adults using CLSA data.

Eur J Clin Nutr 2019 Feb 28. Epub 2019 Feb 28.

Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada.

Background/objectives: Screening for nutrition risk in community-dwelling older adults increases the likelihood of early intervention to improve nutritional status, with short screening tools preferred. SCREEN-II-AB is a valid 8-item tool. The current study determines whether SCREEN-III, a proposed 3-item version, adequately classifies nutrition risk in comparison. Read More

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http://dx.doi.org/10.1038/s41430-019-0411-3DOI Listing
February 2019

Body composition reference charts for UK infants and children aged 6 weeks to 5 years based on measurement of total body water by isotope dilution.

Eur J Clin Nutr 2019 Feb 26. Epub 2019 Feb 26.

Population, Policy, and Practice Programme, UCL Great Ormond Street Institute of Child Health, London, UK.

Background: Until recently, pediatric body composition reference data were very limited, hindering interpretation of measurements. In the last decade, such data emerged for several techniques for children ≥ 5 years, but equivalent data for younger age groups remain lacking, due to their poor compliance with most techniques.

Objectives: To provide reference data for use in clinical practice and research from 6 weeks to 5 years, that are based on measurements of total body water (TBW) by isotope dilution. Read More

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http://dx.doi.org/10.1038/s41430-019-0409-xDOI Listing
February 2019

Socio-economic patterning of food consumption and dietary diversity among Indian children: evidence from NFHS-4.

Eur J Clin Nutr 2019 Feb 26. Epub 2019 Feb 26.

Harvard Center for Population and Development Studies, Harvard University, Cambridge, MA, USA.

Background/objectives: Most interventions to foster child growth and development in India focus on improving food quality and quantity. We aimed to assess the pattern in food consumption and dietary diversity by socioeconomic status (SES) among Indian children.

Subjects/methods: The most recent nationally representative, cross-sectional data from the National Family Health Survey (NFHS-4, 2015-16) was used for analysis of 73,852-74,038 children aged 6-23 months. Read More

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http://dx.doi.org/10.1038/s41430-019-0406-0DOI Listing
February 2019
2.709 Impact Factor

Do we need to re-think the obesity issue?

Eur J Clin Nutr 2019 Feb 26. Epub 2019 Feb 26.

School of Public Health, Curtin University, Perth, WA, Australia.

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http://dx.doi.org/10.1038/s41430-018-0375-8DOI Listing
February 2019

The role of dietary sugars in health: molecular composition or just calories?

Authors:
Philip Prinz

Eur J Clin Nutr 2019 Feb 20. Epub 2019 Feb 20.

Department of Nutritional Sciences, German Sugar Association, Berlin, Germany.

This review will focus on the question of whether dietary sugars are a relevant determinant in the global rise of overweight and obesity in adults, adolescents, and children. Initially, the review describes the current definitions for sugars in the diet and makes reference to them while analyzing their role in overweight and obesity as well as diet-related diseases, including type 2 diabetes, cardiovascular diseases, non-alcoholic fatty liver disease and cancer. Second, it will focus particularly on sucrose and the question of whether it is the molecular composition of sucrose (glucose and fructose) or its energy content that promotes body weight gain and diet-related diseases. Read More

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http://dx.doi.org/10.1038/s41430-019-0407-zDOI Listing
February 2019

Consumption of ultraprocessed foods, nutritional status, and dyslipidemia in schoolchildren: a cohort study.

Eur J Clin Nutr 2019 Feb 20. Epub 2019 Feb 20.

Department of Nutrition, Federal University of Pernambuco, Recife, Brazil.

This study evaluates the relation between consumption of ultraprocessed foods, nutritional status, and dyslipidemia in schoolchildren from Recife/PE, Brazil. This is a cohort study conducted in 2008-2009 and 2012-2013, with 238 students recruited from the public school system of the city of Recife, Northeast Brazil. Demographic data, stage of sexual maturation, socioeconomic, lifestyle, anthropometric, and lipid profiles were collected. Read More

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http://dx.doi.org/10.1038/s41430-019-0404-2DOI Listing
February 2019

Asymptomatic hyperuricemia and incident stroke in elderly Chinese patients without comorbidities.

Eur J Clin Nutr 2019 Feb 20. Epub 2019 Feb 20.

Department of Nephrology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.

Background/objectives: Hyperuricemia is usually associated with other comorbidities; so it is difficult to distinguish the effects of hyperuricemia from other coexisting comorbidities in patients who suffer a stroke.

Subject/methods: Data for this study were collected from the patients of Kangjian Community Health Center of Shanghai. Selected participants ≥65 years of age were available at enrollment (2009-2013). Read More

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http://dx.doi.org/10.1038/s41430-019-0405-1DOI Listing
February 2019
1 Read

Reply to readers' comment on "Body weight difference between dual-energy X-ray absorptiometry and multi-frequency bioelectrical impedance analysis attenuates the equivalence of body composition assessment".

Eur J Clin Nutr 2019 Feb 20. Epub 2019 Feb 20.

Department of Physiology, Ulsan College of Medicine, 388-1 Poongnap-dong, Songpa-Gu, Seoul, 138-736, Republic of Korea.

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http://dx.doi.org/10.1038/s41430-019-0410-4DOI Listing
February 2019
1 Read

Seasonal variation in body mass, body composition and activity-induced energy expenditure: a long-term study.

Eur J Clin Nutr 2019 Feb 20. Epub 2019 Feb 20.

NUTRIM, Maastricht University Medical Centre, Maastricht, The Netherlands.

Background/objectives: Seasonal variation in body mass is a model for the study of body mass regulation. Here a long-term study is presented on body mass, body composition, and activity-induced energy expenditure in a subject with a large seasonal variation in body mass of about 3.0 kg. Read More

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http://dx.doi.org/10.1038/s41430-019-0408-yDOI Listing
February 2019

A systematic literature review of the relation between iron status/anemia in pregnancy and offspring neurodevelopment.

Eur J Clin Nutr 2019 Feb 19. Epub 2019 Feb 19.

The Research Unit for Dietary Studies at The Parker Institute, Bispebjerg and Frederiksberg Hospital, part of the Copenhagen University Hospital, The Capital Region, Copenhagen, Denmark.

Background: The fetal brain starts developing early and animal studies have suggested that iron plays several roles for the development, but results from epidemiological studies investigating associations between gestational iron and offspring neurodevelopment are inconsistent.

Objective: To systematically examine results from observational studies and RCTs on gestational iron and offspring neurodevelopment, with focus on the importance of four domains: iron status indicators, exposure timing, neurodevelopmental outcomes, and offspring age.

Methods: PRISMA guidelines were followed. Read More

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http://dx.doi.org/10.1038/s41430-019-0400-6DOI Listing
February 2019
4 Reads
2.709 Impact Factor

Modelling the health co-benefits of sustainable diets in the UK, France, Finland, Italy and Sweden.

Eur J Clin Nutr 2019 Apr 12;73(4):624-633. Epub 2019 Feb 12.

Centre on Population Approaches for Non-Communicable Disease Prevention, Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK.

Background/objectives: It is not known if diets lower in greenhouse gas (GHG) emissions are also healthier. We evaluated the population health implications of changing to more sustainable diets in the UK, France, Finland, Italy and Sweden.

Subjects/methods: We developed a life table model to simulate mortality and morbidity from diet-related diseases over the lifetime of the current population. Read More

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http://dx.doi.org/10.1038/s41430-019-0401-5DOI Listing

Evidence of higher intramyocellular fat among normal and overweight Indians with prediabetes.

Eur J Clin Nutr 2019 Feb 6. Epub 2019 Feb 6.

Department of Physiology, Pathology, Biostatistics, Orthopaedics and Endocrinology, St John's Medical College and Hospital, Bangalore, Karnataka, India.

Background: The rise in prevalence rates of Type 2 Diabetes among Indians is well recognized. The research focus has been primarily to understand the changes in insulin sensitivity and beta cell dysfunction among Indians with Type 2 Diabetes. However, no data are available on the role of peripheral tissue, in particular intramyocellular lipid (IMCL) content and its impact on glucose homeostasis among Indians with prediabetes. Read More

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http://www.nature.com/articles/s41430-019-0402-4
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http://dx.doi.org/10.1038/s41430-019-0402-4DOI Listing
February 2019
5 Reads

Effect of antenatal and infant micronutrient supplementation on middle childhood and early adolescent development outcomes in Tanzania.

Eur J Clin Nutr 2019 Feb 4. Epub 2019 Feb 4.

Department of Global Health and Population, Harvard T. H. Chan School of Public Health, Boston, MA, USA.

Background: There is growing evidence that nutritional interventions in the first 1000 days of life may influence long-term health and development outcomes. Few studies have examined the effect of maternal and infant micronutrient supplementation on development outcomes in sub-Saharan Africa.

Methods: We conducted a follow-up study of two randomized trials of antenatal and infant micronutrient supplementation conducted in Dar es Salaam, Tanzania. Read More

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http://dx.doi.org/10.1038/s41430-019-0403-3DOI Listing
February 2019
4 Reads

Soy intake and vasomotor menopausal symptoms among midlife women: a pooled analysis of five studies from the InterLACE consortium.

Eur J Clin Nutr 2019 Feb 4. Epub 2019 Feb 4.

School of Public Health, The University of Queensland, Brisbane, Queensland, Australia.

Background/objectives: Phytoestrogen rich-foods such as soy may be associated with less frequent/severe vasomotor menopausal symptoms (VMS), although evidence is limited. We thus investigated the associations between the consumption of soy products and soy milk and the frequency/severity of VMS.

Subjects/methods: We pooled data from 19,351 middle-aged women from five observational studies in Australia, UK, USA, and Japan that contribute to the International Collaboration for a Life course Approach to reproductive health and Chronic disease Events (InterLACE). Read More

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http://dx.doi.org/10.1038/s41430-019-0398-9DOI Listing
February 2019
3 Reads

Psychological disorders and dietary patterns by reduced-rank regression.

Eur J Clin Nutr 2019 Mar 31;73(3):408-415. Epub 2019 Jan 31.

Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Objective: To determine the relationship between dietary patterns identified by reduced-rank regression method and psychological disorders in a large group of Iranian adults.

Methods: A cross-sectional study was performed on 3363 Iranian adults between 20 and 55 years. Dietary intakes were assessed using a validated dish-based semi-quantitative food frequency questionnaire. Read More

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http://dx.doi.org/10.1038/s41430-019-0399-8DOI Listing

Plasma vitamin C concentrations and risk of incident respiratory diseases and mortality in the European Prospective Investigation into Cancer-Norfolk population-based cohort study.

Eur J Clin Nutr 2019 Jan 31. Epub 2019 Jan 31.

Clinical Gerontology Unit, Department of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK.

Background/objectives: Cancerous and non-cancerous respiratory diseases are common and contribute significantly to global disease burden. We aim to quantify the association between plasma vitamin C concentrations as an indicator of high fruit and vegetable consumption and the risk of incident respiratory diseases and associated mortality in a general population.

Subjects/methods: Nineteen thousand three hundred and fifty-seven men and women aged 40-79 years without prevalent respiratory diseases at the baseline (1993-1997) and participating in the European Prospective Investigation into Cancer (EPIC)-Norfolk study in the United Kingdom were followed through March 2015 for both incidence and mortality from respiratory diseases. Read More

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http://dx.doi.org/10.1038/s41430-019-0393-1DOI Listing
January 2019

The interaction of cholesteryl ester transfer protein gene variations and diet on changes in serum lipid profiles.

Eur J Clin Nutr 2019 Jan 31. Epub 2019 Jan 31.

Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background/objectives: Gene-diet interactions may have an important role in the disparities between the lipid responses of individuals to diet. This study aimed to investigate whether polymorphisms (rs5882 and rs3764261) in the cholesteryl ester transfer protein (CETP) gene modify the association of diet with changes in serum lipid profiles.

Subjects/methods: A total of 4700 individuals aged ≥18 years were selected from among participants of the Tehran Lipid and Glucose Study. Read More

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http://dx.doi.org/10.1038/s41430-019-0397-xDOI Listing
January 2019
1 Read

Effects of vitamin D supplements on frequency of CD4 T-cell subsets in women with Hashimoto's thyroiditis: a double-blind placebo-controlled study.

Eur J Clin Nutr 2019 Jan 29. Epub 2019 Jan 29.

Department of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Background: Vitamin D is a modulator of immune functions. Investigations on the mechanisms of vitamin D action and pathogenesis of Hashimoto's thyroiditis (HT) have revealed that vitamin D can reduce damages to thyroid cells caused by autoreactive immune cells.

Methods: Totally, 48 female patients with HT disease were introduced to the study by endocrinologists. Read More

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http://dx.doi.org/10.1038/s41430-019-0395-zDOI Listing
January 2019
1 Read
2.709 Impact Factor

Dietary flaxseed and tamoxifen affect the inflammatory microenvironment in vivo in normal human breast tissue of postmenopausal women.

Eur J Clin Nutr 2019 Jan 28. Epub 2019 Jan 28.

Department of Oncology and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden.

Background: Anti-oestrogens such as tamoxifen, decrease the risk of breast cancer but are unsuitable for prevention because of their side-effects. Diet modifications may be a breast cancer prevention strategy. Here, we investigated if a diet addition of flaxseed, which can be converted to the phytoestrogen enterolactone by the gut microbiota, exhibited similar effects as tamoxifen on normal human breast tissue in vivo, with special emphasis on inflammatory mediators implicated in cancer progression. Read More

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http://dx.doi.org/10.1038/s41430-019-0396-yDOI Listing
January 2019
1 Read

Vitamin D status during pregnancy and offspring outcomes: a systematic review and meta-analysis of observational studies.

Eur J Clin Nutr 2019 Jan 25. Epub 2019 Jan 25.

Research Group in Nutrition and Mental Health (NUTRISAM), Nutrition and Public Health Unit, Faculty of Medicine and Health Sciences, Universitat Rovira i Virgili, Reus, Spain.

Background/objectives: Vitamin D deficiency during pregnancy may influence adverse outcomes in offspring. The aim of this systematic review and meta-analysis of observational studies was to assess the association between low prenatal concentrations of 25(OH)D (by using three different cut-off levels), preterm birth (PTB) and anthropometric and neurodevelopmental outcomes in offspring.

Subjects/methods: Studies reporting data on the association between maternal vitamin D concentrations and offspring outcomes identified through a systematic review of scientific literature published in PubMed/MEDLINE, Scopus and the Cochrane Library databases up to April 2017. Read More

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http://dx.doi.org/10.1038/s41430-018-0373-xDOI Listing
January 2019
1 Read

Body hydration assessment using bioelectrical impedance vector analysis in neurologically impaired children.

Eur J Clin Nutr 2019 Jan 16. Epub 2019 Jan 16.

Paediatric Surgery Department, Children's Hospital "G. Di Cristina", ARNAS Civico-di Cristina-Benfratelli", Palermo, Italy.

Dehydration is common and frequently under-diagnosed in chronic malnourished children, leading to life-threatening conditions. In this pilot study we applied bioimpedance vector analysis (BIVA) to determine hydration status in 52 neurologically impaired (NI) paediatric patients (14.08 ± 5. Read More

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http://dx.doi.org/10.1038/s41430-018-0384-7DOI Listing
January 2019
4 Reads

Anthropometric measurement standardization for a multicenter nutrition survey in children with spinal muscular atrophy.

Eur J Clin Nutr 2019 Jan 15. Epub 2019 Jan 15.

International Center for the Assessment of Nutritional Status (ICANS), Department of Food Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.

Spinal muscular atrophy (SMA) is a neuromuscular disease associated with nutritional status derangement and altered body composition. New drugs are changing the natural history of the disease, so now more than ever is important to focus on the correct assessment of nutritional status in SMA. We implemented a standardization process for the anthropometric measurement as part of our ongoing longitudinal study of growth patterns in SMA patients. Read More

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http://www.nature.com/articles/s41430-019-0392-2
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http://dx.doi.org/10.1038/s41430-019-0392-2DOI Listing
January 2019
4 Reads

Design and characterization of dietary assessment in the German National Cohort.

Eur J Clin Nutr 2019 Jan 15. Epub 2019 Jan 15.

Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Nuthetal, Germany.

Background/objectives: The aim of the study was to describe a novel dietary assessment strategy based on two instruments complemented by information from an external population applied to estimate usual food intake in the large-scale multicenter German National Cohort (GNC). As proof of concept, we applied the assessment strategy to data from a pretest study (2012-2013) to assess the feasibility of the novel assessment strategy.

Subjects/methods: First, the consumption probability for each individual was modeled using three 24 h food lists (24h-FLs) and frequencies from one food frequency questionnaire (FFQ). Read More

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http://www.nature.com/articles/s41430-018-0383-8
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http://dx.doi.org/10.1038/s41430-018-0383-8DOI Listing
January 2019
10 Reads

Differences in the macronutrient and dietary fibre profile of gluten-free products as compared to their gluten-containing counterparts.

Eur J Clin Nutr 2019 Jan 15. Epub 2019 Jan 15.

Instituto de Investigación Sanitaria La Fe, Avenida Fernando Abril Martorell 106, Torre A planta 0, 46026, Valencia, Spain.

Background/objectives: Gluten-free diet is the lifelong therapy for patients with coeliac disease. A wide range of gluten-free products (GFP) is available, which mimics the characteristics of their gluten-containing counterparts (GCC). The aim of this study was to compare the macronutrient and dietary fibre composition of GFP and GCC currently available in Spain. Read More

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http://dx.doi.org/10.1038/s41430-018-0385-6DOI Listing
January 2019
1 Read

Folate intake and the risk of breast cancer: an up-to-date meta-analysis of prospective studies.

Eur J Clin Nutr 2019 Jan 15. Epub 2019 Jan 15.

College of Food Science, Southwest University, No.2 Tiansheng Road, BeiBei District, Chongqing, 400715, China.

Epidemiological studies focusing on the association between folate and breast cancer risk reported inconsistent findings. We conducted a systematic search of the literature using PubMed and EMBASE databases. A total of 23 prospective studies involving 41,516 cases and 1,171,048 individuals were included for meta-analysis. Read More

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http://dx.doi.org/10.1038/s41430-019-0394-0DOI Listing
January 2019
12 Reads
2.709 Impact Factor

Clinical value of body composition monitor to evaluate lean and fat tissue mass in peritoneal dialysis.

Eur J Clin Nutr 2019 Jan 15. Epub 2019 Jan 15.

Departments of Renal Medicine and Transplantation, Barts Health NHS Trust, London, E1 1BB, UK.

Background/objectives: Bioimpedance analysis is often routinely performed in any dialysis unit to guide fluid management but can provide a reproduceable assessment of fat and muscle mass. We wished to determine the clinical significance of low muscle or high fat mass and the determinants that influence their change.

Subjects/methods: We performed retrospective analysis of 824 patients on peritoneal dialysis who underwent routine repeated bioimpedance analysis measurements using the body composition monitor (BCM). Read More

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http://dx.doi.org/10.1038/s41430-019-0391-3DOI Listing
January 2019
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A pilot study of the effect of phospholipid curcumin on serum metabolomic profile in patients with non-alcoholic fatty liver disease: a randomized, double-blind, placebo-controlled trial.

Eur J Clin Nutr 2019 Jan 15. Epub 2019 Jan 15.

Department of Basic Medical Sciences, Neyshabur University of Medical Sciences, Neyshabur, Iran.

Background/objectives: Curcumin, a natural polyphenol compound in the spice turmeric, has been found to have potent anti-oxidative and anti-inflammatory activity. Curcumin may treat non-alcoholic fatty liver disease (NAFLD) through its beneficial effects on biomarkers of oxidative stress (OS) and inflammation, which are considered as two feature of this disease. However, the effects of curcumin on NAFLD have been remained poorly understood. Read More

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http://www.nature.com/articles/s41430-018-0386-5
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http://dx.doi.org/10.1038/s41430-018-0386-5DOI Listing
January 2019
16 Reads

Associations between long-chain PUFAs in maternal blood, cord blood, and breast milk and offspring body composition up to 5 years: follow-up from the INFAT study.

Eur J Clin Nutr 2019 Mar 14;73(3):458-464. Epub 2019 Jan 14.

From the Else Kröner-Fresenius-Center for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Background/objectives: Limited research suggests that exposure to long-chain PUFAs (LCPUFAs) during perinatal development can influence adipose tissue expansion later in life. In previous analyses, we observed that maternal LCPUFAs in late gestation promote offspring gestational growth, whereas breast milk n-3 LCPUFAS promote adipogenesis in infants up to 1 year. This follow-up analysis examines these relationships in offspring up to 5 years. Read More

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http://www.nature.com/articles/s41430-018-0388-3
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http://dx.doi.org/10.1038/s41430-018-0388-3DOI Listing
March 2019
8 Reads

Design and implementation of modified-texture diet in older adults with oropharyngeal dysphagia: a randomized controlled trial.

Eur J Clin Nutr 2019 Jan 14. Epub 2019 Jan 14.

Clinical Nutrition Service, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

Background/objectives: Oropharyngeal dysphagia (OD) is a common problem in elderly population that negatively affects the oral intake and body composition resulting in clinical complications as malnutrition and dehydration. The aim of this study was to design, implement, and evaluate the effect of texture-modified foods and thickened drinks diet, with nectar or pudding viscosity and controlled bolus volume in older adults with OD on body composition and oral intake.

Subjects/methods: Randomized clinical trial, simple blind. Read More

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http://dx.doi.org/10.1038/s41430-019-0389-xDOI Listing
January 2019
5 Reads

Clinical impact of body composition phenotypes in patients with COPD: a retrospective analysis.

Eur J Clin Nutr 2019 Jan 14. Epub 2019 Jan 14.

Department of Physiotherapy, Laboratory of Research in Respiratory Physiotherapy (LFIP), State University of Londrina, Londrina, Brazil.

Background/objectives: Abnormal body composition is an independent determinant of COPD outcomes. To date, it is already known that patient stratification into body composition phenotypes are associated with important outcomes, such as exercise capacity and inflammation, but there are no data comparing physical activity and muscle strength among these phenotypes. Thus, the aim of this study was to compare clinical characteristics and physical function in patients with COPD stratified into body composition phenotypes. Read More

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http://dx.doi.org/10.1038/s41430-019-0390-4DOI Listing
January 2019
5 Reads

Healthy diets and telomere length and attrition during a 10-year follow-up.

Eur J Clin Nutr 2019 Jan 14. Epub 2019 Jan 14.

Folkhälsan Research Center, Helsinki, Finland.

Background: Telomeres are repeats of DNA that contain the sequence TTAGGG at the ends of each chromosome, and their function is to protect DNA from damage. Little evidence exists regarding the relationship between dietary patterns and telomere length, especially derived applying longitudinal design. The aim was to study if overall dietary pattern is associated with leukocyte telomere length (LTL) or faster telomere attrition or both. Read More

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http://dx.doi.org/10.1038/s41430-018-0387-4DOI Listing
January 2019
2 Reads

The effects of curcumin supplementation on liver enzymes, lipid profile, glucose homeostasis, and hepatic steatosis and fibrosis in patients with non-alcoholic fatty liver disease.

Eur J Clin Nutr 2019 Mar 4;73(3):441-449. Epub 2019 Jan 4.

Department of Clinical Nutrition and Dietetics, Faculty of Nutrition and Food Technology, National Nutrition and Food Technology, Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Nonalcoholic fatty liver disease (NAFLD) is a major global health problem. The most common cause of death in these patients is due to cardiovascular disorders. The aim of this study was to examine the effects of curcumin supplementation on cardiovascular risk factors in patients with NAFLD. Read More

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http://www.nature.com/articles/s41430-018-0382-9
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http://dx.doi.org/10.1038/s41430-018-0382-9DOI Listing
March 2019
17 Reads
2.709 Impact Factor

Differences in the incidence of postoperative pneumonia after percutaneous endoscopic gastrostomy between liquid and semi-solid nutrient administration.

Eur J Clin Nutr 2019 Feb 4;73(2):250-257. Epub 2019 Jan 4.

Department of Internal Medicine, Sapporo Kiyota Hospital, Sapporo, Japan.

Background/objectives: This historical control study examined the differences in the incidence of postoperative pneumonia between patients administered liquid and semi-solid nutrients after percutaneous endoscopic gastrostomy (PEG).

Subjects/methods: The medical records of adult patients who underwent PEG between March 1999 and March 2014 were investigated. The patients were administered either liquid or semi-solid nutrient and examined for gastroesophageal reflux via radiography after PEG. Read More

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http://dx.doi.org/10.1038/s41430-018-0380-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368559PMC
February 2019
2 Reads

Serum advanced glycation end products are not associated with muscle strength in hemodialysis patients.

Eur J Clin Nutr 2019 Apr 3;73(4):617-623. Epub 2019 Jan 3.

Graduate Program in Nutrition and Health, Faculty of Nutrition, Federal University of Goias, Goiania, Brazil.

Background: Advanced glycation end products (AGEs) are elevated in patients with renal failure and may potentially affect skeletal muscle. The aim of this study was to evaluate whether serum concentrations of AGEs are associated with muscle strength in hemodialysis (HD) patients, since this association is not clear in the literature.

Methods: This research has a cross-sectional design and included 96 patients on hemodialysis treatment (20-69 years). Read More

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http://dx.doi.org/10.1038/s41430-018-0379-4DOI Listing
April 2019
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CKD autophagy activation and skeletal muscle atrophy-a preliminary study of mitophagy and inflammation.

Eur J Clin Nutr 2019 Jan 3. Epub 2019 Jan 3.

Devision of Nephrology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200080, China.

Background/objectives: Long-lived proteins and organelles, such as mitochondria and the sarcoplasmic reticulum, are degraded by autophagy. However, the specific role of autophagy in chronic kidney disease (CKD) muscle atrophy is still undefined.

Subjects/methods: This was a cross-sectional study with 20 subjects and 11 controls. Read More

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http://dx.doi.org/10.1038/s41430-018-0381-xDOI Listing
January 2019
2 Reads
2.709 Impact Factor

Effects of prebiotics on sepsis, necrotizing enterocolitis, mortality, feeding intolerance, time to full enteral feeding, length of hospital stay, and stool frequency in preterm infants: a meta-analysis.

Eur J Clin Nutr 2018 Dec 19. Epub 2018 Dec 19.

Department of Internal Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.

Background/objectives: Prebiotics are increasingly recognized as an effective measure to promote health and prevent adverse health outcomes in preterm infants. We aimed to systematically review the randomized controlled trials (RCTs) in this area.

Subjects/methods: Relevant studies from January 2000 to June 2018 were searched and selected from PubMed, Medline, Scopus, and the Cochrane Library. Read More

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http://dx.doi.org/10.1038/s41430-018-0377-6DOI Listing
December 2018
1 Read

Secular trends in Dietary Inflammatory Index among adults in the United States, 1999-2014.

Eur J Clin Nutr 2018 Dec 12. Epub 2018 Dec 12.

Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, USA.

Objective: The objective of this study was to evaluate secular trends in Dietary Inflammatory Index (DII) scores in the United States between 1999 and 2014.

Methods: Data from adults over 19 years from the 1999 to 2014 National Health and Nutrition Examination Survey (N = 39,191) were used. DII scores, at each 2-year cycle, were evaluated from a 24-h recall, including 26 food parameters for DII calculation. Read More

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http://dx.doi.org/10.1038/s41430-018-0378-5DOI Listing
December 2018
2 Reads