1,738 results match your criteria European Annals of Allergy and Clinical Immunology [Journal]


Allergic reactions after vaccination: translating guidelines into clinical practice.

Eur Ann Allergy Clin Immunol 2019 Jan 31. Epub 2019 Jan 31.

SOS Allergologia e Immunologia Clinica, Misericordia e Dolce, Italy.

Summary: Vaccination represents one of the most powerful medical interventions on global health. Despite being safe, sustainable, and effective against infectious and in some cases also non-infectious diseases, it's nowadays facing general opinion's hesitancy because of a false perceived risk of adverse events. Adverse reactions to vaccines are relatively rare, instead, and those recognizing a hypersensitivity mechanism are even rarer. Read More

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http://www.eurannallergyimm.com/cont/online-first/654/review
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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.86DOI Listing
January 2019
3 Reads

Venom Immunotherapy: A 20-year experience with an ultra-rush protocol (210-min)

Eur Ann Allergy Clin Immunol 2019 01 31. Epub 2019 Jan 31.

Serviço de Imunoalergologia, Hospital de Santa Maria, Centro Hospitalar Universitário de Lisboa Norte (CHULN), Lisboa, Portugal.

Summary: Ultra-rush (UR) are induction protocols used in venom immunotherapy (VIT). To evaluate the adverse reactions during a 210-minutes UR and determine possible risk factors. Retrospective study of 129 patients submitted to UR with VIT in the last 20 years. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.85DOI Listing
January 2019
2 Reads

The growing importance of real-life studies in allergen immunotherapy.

Eur Ann Allergy Clin Immunol 2019 Jan 31. Epub 2019 Jan 31.

Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.

Summary: Real-life studies offer the opportunity of obtaining outcomes suitable in clinical practice, as controlled trials do not mirror the real patients' population observed in clinical practice. This concept is particularly appropriate for allergen immunotherapy (AIT). Therefore, the current review will present and discuss the most recent and relevant studies published on this topic. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.84DOI Listing
January 2019
2 Reads

Cross-elicitation responses to 2-methoxymethyl-p-phenylenediamine in p-phenylenediamine highly allergic volunteers using allergy alert test: the Italian experience.

Eur Ann Allergy Clin Immunol 2019 Jan 31. Epub 2019 Jan 31.

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA.

Summary: Allergic contact dermatitis after exposure to p-phenylenediamine (PPD)-containing hair dye products is a common and important clinical problem. Because there is a high rate of cross-elicitation of allergic contact dermatitis to other important hair dye products (such as p-toluene diamine [PTD] and other aminophenol hair dyes) in PPD allergic patients, safer alternative dyes with excellent hair coloring options are needed. We studied 2-methoxy methyl-PPD (Me-PPD), a chemical derivative of PPD for tolerance versus cross-elicitation in a cohort of eight PPD-allergic volunteers. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.82DOI Listing
January 2019
1 Read

Allergic bronchopulmonary aspergillosis screening in bronchiectasis: is there always a precise answer to a clear question?

Eur Ann Allergy Clin Immunol 2019 Jan;51(1):41-43

Cardio-Thoracic-Vascular Department, University of Milano Bicocca, Respiratory Unit, San Gerardo Hospital, ASST Monza, Monza, Italy.

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.62DOI Listing
January 2019
2 Reads

Uncovering new potential culprits in drug allergy: non-vitamin K oral anticoagulants.

Eur Ann Allergy Clin Immunol 2019 Jan;51(1):5-6

Internal Medicine Department, Allergy Unit, Rimini Hospital, Rimini, Italy.

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.81DOI Listing
January 2019
1 Read

Spontaneous disappearance of severe latex allergy in an adult.

Authors:
R Asero

Eur Ann Allergy Clin Immunol 2018 Nov 24;50(6):281-282. Epub 2018 Oct 24.

Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano (MI), Italy.

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.55DOI Listing
November 2018
2 Reads

Hypersensitivity reactions to non-vitamin K oral anticoagulants - a review of literature and diagnostic work-up proposal.

Eur Ann Allergy Clin Immunol 2019 Jan 12;51(1):7-14. Epub 2018 Nov 12.

UOC Medicina Interna e Reumatologia, Allergologia, Ospedale Infermi, Rimini, Italy.

Summary: Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly being used in hospital and outpatient settings as safe alternatives to warfarin. Hypersensitivity reactions have been described for NOACs and can be classified according to Gell and Coombs. We reviewed case reports of possible drug hypersensitivity reactions, noticing a predominance of delayed reactions (both mild and severe) and the absence of cross-reactions to warfarin and low molecu-lar weight heparins. Read More

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http://www.eurannallergyimm.com/cont/online-first/642/review
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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.80DOI Listing
January 2019
20 Reads

Cost-effectiveness of the SQ HDM SLIT-tablet for the treatment of allergic asthma in three Eastern European Countries.

Eur Ann Allergy Clin Immunol 2018 Nov 12. Epub 2018 Nov 12.

ALK-Abelló, Denmark.

Summary: The standardized quality (SQ®) house dust mite (HDM) sublingual immunotherapy (SLIT)-tablet (acarizax®, ALK-Abelló A/S, Hørsholm, Denmark) is an allergy immunotherapy tablet for people with allergic respiratory disease. This analysis aims to assess the cost-effectiveness of the SQ HDM SLIT-tablet from the perspective of three Eastern European countries: Czech Republic, Poland and Slovakia. A cost-utility model per country was developed, which compared the SQ HDM SLIT-tablet as add-on to pharmacotherapy with pharmacotherapy alone in patients with HDM allergic asthma (AA) over a five year time horizon. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.78DOI Listing
November 2018
4 Reads

Infectious etiology of chronic diarrhea in patients with primary immunodeficiency diseases.

Eur Ann Allergy Clin Immunol 2019 Jan 12;51(1):32-37. Epub 2018 Nov 12.

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.

Summary: Primary immunodeficiency diseases (PIDs) are life-threatening disorders, which manifest commonly with gastrointestinal (GI) signs, mainly as chronic diarrhea. To investigate and compare infectious etiology of chronic diarrhea in different PIDs. Assessing clinical features, obtaining immunological profiles, as well as characterizing infectious etiology of diarrhea were performed in 38 PID patients with chronic diarrhea. Read More

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http://www.eurannallergyimm.com/cont/online-first/640/origin
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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.77DOI Listing
January 2019
11 Reads

The role of mobile apps in allergic respiratory diseases: an Italian multicentre survey report.

Eur Ann Allergy Clin Immunol 2018 Nov 15;50(6):268-272. Epub 2018 Oct 15.

Allergy and Respiratory Diseases, University of Genoa, Genoa, Italy.

Summary: We performed a multicentre survey about the role of mobile apps in allergic respiratory diseases. The main objective was to investigate the current use and usefulness of mobile phone apps in the management of allergic respiratory disease. An original questionnaire including 12 multiple-choice questions was administered to 360 participants (153 male and 207 female subjects). Read More

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http://www.eurannallergyimm.com/cont/online-first/627/origin
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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.76DOI Listing
November 2018
16 Reads

Bet v 1 sensitization modulates allergenic molecular immune response.

Eur Ann Allergy Clin Immunol 2019 Jan 24;51(1):21-31. Epub 2018 Sep 24.

Pediatric Pneumology, IRCCS-Istituto Giannina Gaslini, Genoa, Italy.

Summary: Allergy is characterized by allergen-specific IgE production. Molecular-based allergy diagnostic allows to define the precise sensitization profile. Bet v 1 is the major allergen of the PR-10 family. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.73DOI Listing
January 2019
3 Reads

Impact of allergy on children with attention deficit hyperactivity disorder.

Eur Ann Allergy Clin Immunol 2018 Nov 1;50(6):262-267. Epub 2018 Aug 1.

Department of Internal Medicine, Allergy and Clinical Immunology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Summary: Background. Attention deficit hyperactivity disorder (ADHD) is commonly present worldwide, causing serious problems to those affected. ADHD was suggested to be secondary to allergic disorder or its medication. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.72DOI Listing
November 2018
15 Reads

Delayed hypersensitivity to new oral anticoagulants. Demonstration of cross reactivity for the drug category and definition of non-irritant concentrations for patch tests.

Eur Ann Allergy Clin Immunol 2019 Jan 1;51(1):38-40. Epub 2018 Aug 1.

Internal Medicine Department, Allergy Unit, Rimini Hospital, Rimini, Italy.

Summary: The current therapy with direct trombin inhibitors (DTI) is indicated for the prevention of stroke in non-valvular atrial fibrillation. Side effects are reported, particularly skin hypersensitivity, for this whole category of drugs as well as for other modern antiplatelet and anticoagulant drugs. For their clinical features, these reactions appear as delayed T-cell mediated drug hypersensitivity, but at present there are no diagnostic methods of investigation. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.71DOI Listing
January 2019
4 Reads

Hyperlipidemia in association with pro-inflammatory cytokines among chronic spontaneous urticaria: case-control study.

Eur Ann Allergy Clin Immunol 2018 Nov 1;50(6):254-261. Epub 2018 Aug 1.

Department of Clinical and Chemical Pathology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Summary: Chronic spontaneous urticaria (CSU) is a disorder characterized by recurrent transient itchy wheels of 6 weeks duration or longer. The cause cannot be pinpointed in about 40% of patients. To elucidate the possible association between CSU and hyperlipidemia, 40 CSU patients and 40 group matched healthy individuals were assessed for hyperlipidemia. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.68DOI Listing
November 2018
5 Reads

Allergy in adolescent population (14-18 years) living in Campania region (Southern Italy). A multicenter study.

Eur Ann Allergy Clin Immunol 2019 Jan 1;51(1). Epub 2018 Aug 1.

Allergy Unit, National Healthcare System, Reggio Calabria, Italy.

Summary: Adolescents (Ad) constitute a difficult to manage population among individuals suffering from asthma. The aim of our study was to assess the prevalence, clinical characteristics and age of onset of allergic sensitization and clinical symptoms in a sample of atopic Ad living in the Campania region (Southern Italy). Sixteen Allergy units or Centers belonging to the Italian Association of Hospital and Territorial Allergologists (AAIITO, Campania region) participated in this cross-sectional study. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.65DOI Listing
January 2019
4 Reads

Fatal asthma after omalizumab and controller therapy discontinuation.

Eur Ann Allergy Clin Immunol 2018 Jul 24;50(5):235-236. Epub 2018 Jul 24.

Allergy and Respiratory Diseases, University of Genoa, Genova, Italy.

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.70DOI Listing
July 2018
8 Reads

Severe asthma in adolescents and adults: a national, multicenter registry in real life.

Eur Ann Allergy Clin Immunol 2018 Sep 24;50(5):196-201. Epub 2018 Jul 24.

Unità Operativa Complessa di Pneumologia, ASST-Rhodense , Garbagnate Milanese (MI), Italy.

Summary: The number of patients with uncontrolled asthma is growing especially in young people. Although current therapies improve the disease management, the heterogeneity of clinical outcomes results in patients whose asthma is refractory to standard therapies. To understand not responsive phenotypes, we instituted a web-registry aimed to collect real life data of adolescent and adult patients. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.69DOI Listing
September 2018
3 Reads

An atlas of IgE sensitization patterns in different Italian areas. A multicenter, cross-sectional study.

Eur Ann Allergy Clin Immunol 2018 Sep 24;50(5):217-225. Epub 2018 Jul 24.

Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano (MI), Italy.

Summary: The development of recombinant technology supported the allergy diagnostic work-up in the daily clinical practice, representing a useful tool for epidemiological studies. An atlas of the IgE sensitization profiles found throughout Italy was prepared from a nationwide, multicenter, cross-sectional study. 6052 unselected consecutive individuals, belonging to North-West [NW], North-East [NE], Centre [C], South [S], and Islands subset [Is] were evaluated by means of the ImmunoCAP ISAC test. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.67DOI Listing
September 2018
4 Reads

Banana lectin (BanLec) induces non-specific activation of basophils and mast cells in atopic subjects.

Eur Ann Allergy Clin Immunol 2018 Nov 24;50(6):243-253. Epub 2018 Jul 24.

Department of Biochemistry and Nutrition, CSIR-Central Food Technological Research Institute (CFTRI), Mysuru, Karnataka State, India.

Summary: Dietary lectins play a major role in the activation of mast cells / basophils by bridging cell surface IgE glycans to release histamine and other mediators. In the present study, the effect of mannose / glucose-specific banana lectin (BanLec) on the activation of mast cells / basophils from non-atopic and atopic subjects has been investigated. BanLec was purified from banana pulp in a yield of 7 mg/kg. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.64DOI Listing
November 2018
2 Reads

Drug-induced anaphylaxis: seven-year single-center survey.

Eur Ann Allergy Clin Immunol 2018 Sep 20;50(5):211-216. Epub 2018 Jul 20.

Immunoallergy Department, CUF Descobertas Hospital, Lisbon, Portugal.

Summary: Drug-induced anaphylaxis (DIA) is the most common cause of fatal anaphylaxis. We aimed to characterize patients with DIA and their allergological workup. Systematic review of patients with history of DIA referred to our center over 7 years. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.66DOI Listing
September 2018
2 Reads

Lipid transfer protein sensitization in an apple-allergic patient: a case report from northern Europe.

Authors:
A Gülsen U Jappe

Eur Ann Allergy Clin Immunol 2018 Mar 2. Epub 2018 Mar 2.

Division of clinical and molecular allergology, Research Center Borstel, Airway Research Center North (ARCN), member of the German Center for lung research, Borstel, Germany.

Summary: We describe a case of a woman who developed three separate episodes of urticaria and ana-phylaxis during exercise after consuming an apple, with immunological evidence that nonspecific lipid transfer proteins (LTP) may have been responsible for these reactions. LTP sensitivity can cause life-threatening allergies and anaphylaxis. Although LTP sensitization is common in Mediterranean countries, the frequency of knowledge and diagnoses is increasing in Europe. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.63DOI Listing
March 2018
10 Reads

Allergy to LTP: to eat or not to eat sensitizing foods? A follow-up study.

Eur Ann Allergy Clin Immunol 2018 Jul 16;50(4):156-162. Epub 2018 Feb 16.

UOC Medicina Generale - Immunologia e Allergologia, IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Summary: Follow-up data about the onset of novel food allergies in patients allergic to lipid transfer protein (LTP) are missing. We investigated the occurrence of novel allergies over time in LTP hypersensitive patients. Sixty-seven LTP-allergic patients recommended to avoid foods responsible for systemic reactions and encouraged to eat other sensitizing foods avoiding the association with known co-factors, were re-evaluated after ≥ 1 year to assess the occurrence of allergy to novel foods. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.57DOI Listing
July 2018
8 Reads

Effect of industrial processing on the IgE reactivity of three commonly consumed Mo-roccan fish species in Fez region.

Eur Ann Allergy Clin Immunol 2018 Sep 2;50(5):202-210. Epub 2018 Mar 2.

Laboratory of Bioactive Molecules (LMBSF), University Sidi Mohamed Ben Abdellah, Faculty of Sciences and Techniques, Fez, Morocco.

Summary: The aim of this work was to study the effect of industrial processing on the allergenicity of three commonly consumed Moroccan fish species in Fez region (sardine, common pandora, and shrimp). This work was conducted by a sera-bank obtained from 1248 patients recruited from Fez Hospitals. Their sera were analyzed for specific IgE binding to raw fish extracts. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.61DOI Listing
September 2018
11 Reads

Reduction of the allergenicity of cow's milk α-lactalbumin under heat-treatment and enzymatic hydrolysis in Moroccan population.

Eur Ann Allergy Clin Immunol 2018 Jul 1;50(4):177-183. Epub 2018 Mar 1.

Laboratory of Bioactive Molecules (LBM), Faculty of Sciences and Technology, Sidi Mohamed Ben Abdellah University, Fez, Morocco.

Summary: The aim of the present study is to evaluate the effect of heat-treatment and enzymatic hydrolysis on the allergenicity of cow's milk α-lactalbumin (α-LA) in a Moroccan population. A total of 557 patients were recruited from the University Hospital Complex and the Ibn El Khatib Hospital of Fez city. This population consented to realize a dosage of IgE levels to raw cow milk and then to α-LA native and treated with the studied treatments. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.60DOI Listing
July 2018
10 Reads

Oral allergy syndrome amongst young Mexicans: prevalence and associated factors.

Eur Ann Allergy Clin Immunol 2019 Jan 28;51(1):15-20. Epub 2018 Feb 28.

Centro de Investigación en Ciencias Médicas, Universidad Autónoma del Estado de México, Toluca de Lerdo, México.

Summary: Oral allergy syndrome (OAS) is the most common food allergy manifestation amongst adults. However, population studies aimed at estimating its prevalence and associated factors are scarce in Mexi-co. To establish the prevalence of OAS in a sample of university students and to describe their clinical characteristics and its associated factors. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.59DOI Listing
January 2019
9 Reads

Histamine-release test in angioedema patients without urticaria - a retrospective cohort study of 404 patients.

Eur Ann Allergy Clin Immunol 2018 07 19;50(4):163-168. Epub 2018 Feb 19.

Department of Dermatology and Allergy Centre, Odense University Hospital, Odense, Den-mark.

Summary: A subset of patients with angioedema (AE) and urticaria has histamine releasing autoantibodies. The histamine release test (HR-test) has been used as a tool in chronic urticaria to define the autoimmune subgroup and may possibly guide the clinician to a more personalized therapy, like omalizumab and cyclosporine. The prevalence and value of positive histamine releasing autoantibodies in monosymptomatic AE is sparsely described in the literature. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.58DOI Listing
July 2018
10 Reads

Omalizumab in chronic spontaneous and inducible urticaria: a 9 year retrospective study in Portugal.

Eur Ann Allergy Clin Immunol 2018 Jul 16;50(4):169-176. Epub 2018 Jan 16.

Immunoallergology Department, Santa Maria Hospital, Centro Hospitalar Lisboa Norte, Lisbon, Portugal.

Summary: Describe the safety and long-term use of omalizumab in chronic urticaria (CU), both spontaneous (CSU) and inducible (CIndU). Retrospective chart-review (2006-15) of CU patients treated with omalizumab for ≥ 6 months. Statistical analyses: descriptive statistics, Mann-Whitney, generalized linear models. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.51DOI Listing
July 2018
7 Reads

Role of nasal challenge and local eosinophilia in indirect exposure to cat in allergic rhinitis patients.

Eur Ann Allergy Clin Immunol 2018 May 17;50(3):125-131. Epub 2018 Jan 17.

Al-Rashed Allergy Center, Ministry of health, Kuwait.

Summary: Sensitization to cat allergens is common worldwide. Currently, there is a trend towards costly and often unavailable diagnostic analysis. The aim is to assess the reliability of skin prick test (SPT) and serum specific IgE (ssIgE) to cat sensitization, by performing nasal challenge test (NCT) in a community with low cat ownership but common presence of stray cats. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.50DOI Listing
May 2018
6 Reads

Storage molecules from tree nuts, seeds and legumes: relationships and amino acid identity among homologue molecules.

Eur Ann Allergy Clin Immunol 2018 Jul 1;50(4):148-155. Epub 2018 Feb 1.

Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano, Milan, Italy.

Summary: The families of seed storage proteins, together with profilins, oil-bodies-associated oleosins, and pathogenesis-related (PR) proteins like PR-10 (Bet v 1-like), PR-12 (defensins) and PR-14 (non-specific lipid transfer protein), are the main causes of IgE sensitization to tree nuts, legumes and seeds. All these allergens, with the exclusion of profilins and of PR-10, are heat-stable and possibly responsible for fatal or almost fatal adverse reactions to such foods. In this short review, we will discuss the relationship and amino acid identities among some of the seed storage homologue molecules identified to date from tree nuts, seeds and legumes. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.54DOI Listing
July 2018
7 Reads

Latex sensitization in patients with myelomeningocele: contribution of microarray technique.

Eur Ann Allergy Clin Immunol 2018 May 15;50(3):135-138. Epub 2018 Jan 15.

Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Escola Paulista de Medicina-Federal University of São Paulo, São Paulo, Brazil.

Summary: Microarray technique employing molecular allergens is pointed out as a new method to evaluate allergic patients. To evaluate if microarray technique (ImmunoCAP-ISAC®; I-ISAC®) is similar to fluorescence enzyme immunoassay (FEIA; ImmunoCAP®) in the diagnosis of latex allergy (specific IgE to latex plus symptoms) and latex sensitization (only antibody) in pediatric (9-mo to 14-yrs) patients with myelomeningocele undergone to surgical repair. Patients underwent skin prick testing (SPT) to latex and food (prick to prick), and dosage of serum specific IgE to latex and recombinant latex allergens (rHev b 1, rHev b 3, rHev b 5, rHev b 6. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.52DOI Listing
May 2018
10 Reads

Galactose-α-1,3-galactose allergy: a rare syndrome and an atypical presentation.

Eur Ann Allergy Clin Immunol 2018 Jul 15;50(4):190-192. Epub 2018 Jan 15.

Department of Immunoallergology, Hospital de Santo António, Centro Hospital do Porto, Oporto, Portugal.

Summary: Allergies to red meat associated with galactose-α-1,3-galactose, commonly known as α-gal, are rare and have only recently been described. At this time, the literature reports only one case documented in Portugal. In this study, we report the case of a 76-year-old male with an immediate reaction following the ingestion of red meat. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.49DOI Listing
July 2018
4 Reads

Fecal microbiota profile in atopic asthmatic adult patients.

Eur Ann Allergy Clin Immunol 2018 May 15;50(3):117-124. Epub 2018 Jan 15.

Department of allergy and clinical immunology, Faculty of medicine, Ain Shams University, Cairo, Egypt.

Summary: Studies proposed a link between gut microbiota and airway tract. Study the diversity and density of gut microbiota in healthy and asthmatic patients. Semi-quantitative stool cultures were performed from fecal samples collected from 80 adult asthmatic patients and 40 healthy individuals. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.48DOI Listing
May 2018
5 Reads

Localized salt-dependent aquagenic urticaria, a rare subtype of urticaria: a case report.

Eur Ann Allergy Clin Immunol 2018 May 20;50(3):141-144. Epub 2017 Nov 20.

Immunoallergy Department, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.

Summary: Aquagenic urticaria (AU) is a rare form of chronic inducible urticaria elicited by water at any temperature. We describe the case of a 25-year-old atopic woman who presented to our unit with a 4-year history of recurrent urticarial rashes, highly pruritic, confined to the neck and lower part of the face, occurring solely on contact with sea water. The lesions were reproduced by challenge tests with aqueous 3. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.56DOI Listing
May 2018
6 Reads

Paediatric case series of drug reaction with eosinophilia and systemic symptoms (DRESS): 12-year experience at a single referral centre in Hong Kong and the first reported use of infliximab.

Eur Ann Allergy Clin Immunol 2018 Nov 30;50(6):273-276. Epub 2017 Nov 30.

Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Hong Kong.

Summary: DRESS (drug reaction with eosinophilia and systemic symptoms) is a rare but potentially life-threatening disorder characterized by fever, skin eruption, haematological abnormalities and multi-organ dysfunction after drug exposure. The pathophysiology is thought to be related to interactions between culprit drugs, viral reactivation and T-lymphocytes activation. We report 4 paediatric patients with DRESS who were treated at our centre over the past 12 years. Read More

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http://www.eurannallergyimm.com/cont/journals-articles/636/v
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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.47DOI Listing
November 2018
14 Reads

Vitamin D receptor variants and uncontrolled asthma.

Eur Ann Allergy Clin Immunol 2018 May 28;50(3):108-116. Epub 2017 Nov 28.

School of Chemistry, National University of Ireland, Galway, Ireland. Institute for Regenerative Medicine, Sechenov First Moscow State Medical University, Moscow, Russia.

Summary: Asthma is a common childhood respiratory disease, affecting around 20% of Irish children. In other populations, vitamin D receptor (VDR) polymorphisms have been associated with asthma risk. We aimed to investigate the association between 2 VDR polymorphisms and uncontrolled paediatric asthma. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.46DOI Listing
May 2018
3 Reads

Anaphylaxis in a food allergy outpatient department: one-year review.

Eur Ann Allergy Clin Immunol 2018 Mar 30;50(2):81-88. Epub 2017 Nov 30.

Allergy and Clinical Immunology Department, Coimbra University Center, Coimbra, Portugal.

Summary: Anaphylaxis is an acute, potentially fatal, multi-organ allergic reac-tion. Our aim was to characterize the population with food induced anaphylaxis followed over a one-year period. Retrospective analysis of clinical files of patients with food anaphylaxis observed in our food allergy consultation during 2016. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.45DOI Listing
March 2018
31 Reads

Food protein-induced enterocolitis syndrome in children: what's known? What's new?

Eur Ann Allergy Clin Immunol 2018 May 24;50(3):99-107. Epub 2017 Nov 24.

Department of Pediatrics, G. D'Annunzio University, Chieti, Italy.

Summary: Food protein-induced enterocolitis syndrome (FPIES) is an under-recognized and frequently misdiagnosed non-IgE mediated food allergy syndrome. Affected infants show gastrointestinal symptoms few hours after ingestion of the incriminating food. Pathophysiology of FPIES has not yet been clearly defined and needs further characterization. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.44DOI Listing
May 2018
4 Reads

Freshly squeezed: anaphylaxis caused by drone larvae juice.

Eur Ann Allergy Clin Immunol 2018 Sep 30;50(5):232-234. Epub 2017 Nov 30.

Department of Dermatology, Venereology, and Allergology, University Hospital Würzburg, Würzburg, Germany.

Summary: Drone larvae are mostly considered a by-product of beekeeping, but have recently been advo-cated as a high-protein source of food. There are as yet no data concerning their allergenic potential. We report on a 29-year old bee keeper who experienced an anaphylactic reaction following the consumption of a freshly prepared beverage from raw drone larvae. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.43DOI Listing
September 2018
7 Reads

Hypersensitivity to antiretroviral drugs.

Eur Ann Allergy Clin Immunol 2018 Nov 20;50(6):277-280. Epub 2017 Nov 20.

Immunoallergology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.

Summary: Antiretroviral therapy (ART) may be responsible for hypersensitivity reactions varying in severity, clinical manifestations and frequency. We report the case of a 47-year-old woman with HIV infection who developed a delayed mucocutaneous reaction after treatment with ART. Hypersensitivty reaction (HR) to emtricitabine and tenofovir was considered probable based on positive patch tests (PT) and hypersensitivity reaction to nevirapine was confirmed by drug provocation test. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.42DOI Listing
November 2018
5 Reads

Dog allergy: can a prevalent or exclusive sensitization to Can f 5 be considered a lucky or negative event in real life?

Eur Ann Allergy Clin Immunol 2018 Nov 30;50(6):283-285. Epub 2017 Nov 30.

Postgraduate School of Respiratory Medicine, Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy. Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome Tor Vergata, Rome, Italy.

Summary: Recent studies have shown the increasing relevance of allergic sensitization to Can f 5 (a prostatic kallikrein), which is an androgen-regulated protein expressed in the prostate and detectable only in male dogs. Can f 5 can be a prevalent or exclusive sensitizing agent in a considerable percentage of dog-allergic patients. Its specific allergenic characteristics are able to induce possible negative as well as positive clinical effects in individuals sensitized to dogs. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.41DOI Listing
November 2018
5 Reads

Immunogenetics of cytokine genes in parthenium dermatitis: a review.

Eur Ann Allergy Clin Immunol 2018 Mar 27;50(2):59-65. Epub 2017 Nov 27.

Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.

Summary: Parthenium dermatitis is a chronic immuno-inflammatory, distressing skin disease and is mediated by activated T-lymphocyte which is primarily manifested on the exposed sites of the face, neck, hand and flexures. Parthenium hysterophorus is ubiquitous, hence it is diffi-cult to avoid the aero-allergenic antigen parthenin, responsible for the contact dermatitis. The pathogenesis of parthenium dermatitis is characterized by infiltration of T-lymphocytes into challenged skin sites and the development of a cutaneous inflammation due to altered regulatory network of pro and anti-inflammatory cytokines. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.40DOI Listing
March 2018
5 Reads

Systematic investigation for underlying causes of recurrent infections in children: surveillance of primary immunodeficiency.

Eur Ann Allergy Clin Immunol 2018 Mar 21;50(2):72-80. Epub 2017 Nov 21.

Research Center for Immunodeficiencies, Pediatrics Center of Excellence, Children s Medical Center, Tehran University of Medical Science, Tehran, Iran.

Summary: Recurrent infections seem to be a common complaint in children who are referred to general practitioners and pediatricians offices. Detection of primary immunodeficiencies (PID) etiology is very important for achieving appropriate diagnosis and treatment of these patients. The absence of appropriate treatment could lead to subsequent complications, in a hospital inpatient and/or outpatient settings. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.39DOI Listing
March 2018
6 Reads

Local anesthetics allergy: who should be tested?

Eur Ann Allergy Clin Immunol 2018 Mar 22;50(2):66-71. Epub 2017 Nov 22.

Ankara University School of Medicine, Department of Chest Diseases, Division of Im-munology and Allergy, Ankara, Turkey.

Summary: To document the test results of patients referred to our clinic for testing with local anesthetics (LAs) in real life conditions and provide data related to the necessity of these tests. All consecutive subjects who were referred to be evaluated for LA allergy during a two-year follow up were included in the analysis. All subjects underwent skin prick / intradermal tests followed by a subcutaneous provocation test with the LAs tested. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.38DOI Listing
March 2018
3 Reads

Patch testing in a case of eslicarbazepine and carbamazepine induced cutaneous reaction.

Eur Ann Allergy Clin Immunol 2018 Sep 29;50(5):229-231. Epub 2017 Nov 29.

Immunoallergology Department, Dona Estefânia Hospital, Centro Hospitalar Lisboa Central, Lisbon, Portugal.

Summary: Anticonvulsants are among the drugs most commonly involved in cutaneous adverse drug reactions (CADRs). Eslicarbazepine is a new anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. We report the clinical case of a woman who developed a skin rash on day 10 of eslicarbazepine with further exacerbation with eosinophilia on day 2 of carbamazepine. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.37DOI Listing
September 2018
7 Reads

Restoration of aspirin tolerance following omalizumab treatment in a patient with chronic spontaneous urticaria.

Authors:
R Asero

Eur Ann Allergy Clin Immunol 2018 Sep 30;50(5):226-228. Epub 2017 Nov 30.

Ambulatorio di Allergologia, Clinica San Carlo, Paderno Dugnano (MI), Italy.

Summary: Up to 30% of cases of chronic spontaneous urticaria (CSU) are exacerbated by COX-1 inhibiting nonsteroidal anti-inflammatory drugs (NSAID); this clinical picture is termed NECD (NSAID-exacerbated cutaneous disease). On the other hand, multiple NSAID hypersensitivity may occur in the absence of an underlying CSU also, a situation that is termed NIUA (NSAID-induced urticaria / angioedema). The present study reports a case of multiple NSAID hypersensitivity that occurred in a man much before he developed severe CSU. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.36DOI Listing
September 2018
8 Reads

Recommendations for the use of molecular diagnostics in the diagnosis of allergic dis-eases.

Eur Ann Allergy Clin Immunol 2018 Mar 27;50(2):51-58. Epub 2017 Nov 27.

Servizio di Allergologia, Casa della Salute di Scilla, Scilla (RC), Italy. Associazione Italiana degli Allergologi e Immunologi Territoriali e Ospedalieri (AAIITO).

Summary: The Study Group on Allergology of the Italian Society of Clinical Pathology and Laboratory Medicine (SIPMeL) and the Associazione Italiana degli Allergologi e Immunologi Territoriali e Ospedalieri (AAIITO) developed the present recommendations on the diagnosis of allergic diseases based on the use of molecular allergenic components, whose purpose is to provide the pathologists and the clinicians with information and algorithms enabling a proper use of this second-level diagnostics. Molecular diagnostics allows definition of the exact sensitization profile of the allergic patient. The methodology followed to develop these recommendations included an initial phase of discussion between all the components to integrate the knowledge derived from scientific evidence, a revision of the recommendations made by Italian and foreign experts, and the subsequent production of this document to be disseminated to all those who deal with allergy diagnostics. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.32DOI Listing
March 2018
5 Reads

An unusual case of wheat dependent exercise induced anaphylaxis (WDEIA) triggered by Tri a 14 in a pediatric patient: a case report.

Eur Ann Allergy Clin Immunol 2018 Jul 23;50(4):187-189. Epub 2017 Nov 23.

UOC Pediatria e Neonatologia, Ospedale Guglielmo da Saliceto, Piacenza, Italia.

Summary: Anakinra, one of the novel biological agents, is a recombinant human IL-1 receptor antagonist. It is preferred as an alternative drug for familial Mediterranean fever cases where colchicine is not sufficient or cannot be used due to its side effects. Like all other biologics, hypersensitivity reactions to anakinra are quite rare. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.31DOI Listing
July 2018
12 Reads

Successful rapid subcutaneous desensitization to anakinra in a case with a severe immediate-type hypersensitivity reaction.

Eur Ann Allergy Clin Immunol 2018 Mar 22;50(2):94-96. Epub 2017 Nov 22.

Erciyes University School of Medicine, Department of Chest Diseases, Division of Allergy and Clinical Immunology, Kayseri, Turkey.

Summary: Anakinra, one of the novel biological agents, is a recombinant human IL-1 receptor antagonist. It is preferred as an alternative drug for familial Mediterranean fever cases where colchicine is not sufficient or cannot be used due to its side effects. Like all other biologics, hypersensitivity reactions to anakinra are quite rare. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.30DOI Listing
March 2018
6 Reads

Piperacillin-tazobactam anaphylaxis: a rare cause of occupational disease.

Eur Ann Allergy Clin Immunol 2018 Mar 20;50(2):89-91. Epub 2017 Nov 20.

Serviço de Imunoalergologia, Hospital de Dona Estefânia, Centro Hospitalar de Lisboa Central, Lisbon, Portugal; CEDOC, Faculdade de Ciências Médicas (FCM), Universidade Nova de Lisboa, Lisbon, Portugal.

Summary: Piperacillin is a beta-lactam antibiotic of penicillin family. Some penicillins were report-ed as occupational diseases cause, but piperacillin anaphylaxis with occupational sensi-tization is rare. We describe the case of a female nurse with recurrent anaphylaxis in last few months without apparent cause, only in work environment. Read More

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http://dx.doi.org/10.23822/EurAnnACI.1764-1489.29DOI Listing
March 2018
8 Reads