5,316 results match your criteria Europace[Journal]


Long-term results of atrial maze surgery in patients with congenital heart disease.

Europace 2019 Apr 19. Epub 2019 Apr 19.

Department of Cardiovascular Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Aims: Recurrent atrial tachycardia is common after repair of many types of congenital heart disease, and surgical ablation with a maze procedure represents a potential treatment strategy. The objective of this study is to report a single-centre 19 years' experience with maze surgery in congenital heart patients.

Methods And Results: Patients undergoing maze procedure concomitantly with cardiac surgical procedures were retrospectively analysed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz056DOI Listing
April 2019
1 Read

Heparin dosing in uninterrupted anticoagulation with dabigatran vs. warfarin in atrial fibrillation ablation: RE-CIRCUIT study.

Europace 2019 Apr 14. Epub 2019 Apr 14.

University of California, San Francisco, CA, USA.

Aims: To describe heparin dosing requirements in patients who underwent catheter ablation of atrial fibrillation with uninterrupted anticoagulation using dabigatran etexilate (dabigatran) or warfarin to attain therapeutic activated clotting time (ACT) in the RE-CIRCUIT® study. The RE-CIRCUIT study showed significantly fewer major bleeding events in the dabigatran vs. warfarin treatment group. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz057DOI Listing
April 2019
2 Reads

Percutaneous transhepatic route for cardiac resynchronization therapy in a patient with superior vena cava occlusion.

Europace 2019 Apr 14. Epub 2019 Apr 14.

Department of Cardiology, West China Hospital, Sichuan University, 37 Guoxue Alley, Chengdu 610041, PR China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz024DOI Listing

Postpartum hormones oxytocin and prolactin cause pro-arrhythmic prolongation of cardiac repolarization in long QT syndrome type 2.

Europace 2019 Apr 1. Epub 2019 Apr 1.

Department of Cardiology and Angiology I, Heart Center University of Freiburg, Hugstetter Str. 55, Freiburg, Germany.

Aims: Women with long QT syndrome 2 (LQT2) have a particularly high postpartal risk for lethal arrhythmias. We aimed at investigating whether oxytocin and prolactin contribute to this risk by affecting repolarization.

Methods And Results: In female transgenic LQT2 rabbits (HERG-G628S, loss of IKr), hormone effects on QT/action potential duration (APD) were assessed (0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz037DOI Listing
April 2019
2 Reads

Corrigendum.

Authors:

Europace 2019 Mar 29. Epub 2019 Mar 29.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz040DOI Listing
March 2019
1 Read

End-of-service management of leadless cardiac pacemakers: a case report.

Europace 2019 Mar 26. Epub 2019 Mar 26.

Department of Cardiology, Trousseau Hospital, University of Tours, 37044 Tours, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz054DOI Listing
March 2019
2 Reads

Association between antithrombotic treatment and outcomes at 1-year follow-up in patients with atrial fibrillation: the EORP-AF General Long-Term Registry.

Europace 2019 Mar 24. Epub 2019 Mar 24.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK.

Aims: In recent years, stroke prevention in patients with atrial fibrillation (AF) has radically changed, with increasing use of non-vitamin K antagonist oral anticoagulants (NOACs). Contemporary European data on AF thromboprophylaxis are needed.

Methods And Results: We report 1-year follow-up data from the EURObservational Research Programme in Atrial Fibrillation (EORP-AF) General Long-Term Registry. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz032DOI Listing
March 2019
1 Read

Mortality and morbidity reduction after frequent premature ventricular complexes ablation in patients with left ventricular systolic dysfunction.

Europace 2019 Mar 24. Epub 2019 Mar 24.

Hospital Clínic and IDIBAPS, Barcelona, Spain.

Aims: Ablation of frequent premature ventricular complexes (PVCs) improves left ventricular ejection fraction in patients with left ventricular (LV) systolic dysfunction. This study aims to evaluate the long-term hard outcomes and potential prognostic variables in this population.

Methods And Results: Prospective multicentre study including 101 consecutive patients [56 ± 12 years old, 62 (61%) men] with LV systolic dysfunction and frequent PVCs who underwent PVC ablation before November 2015. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz027DOI Listing
March 2019
1 Read

Predictors of mortality and heart transplantation in patients with Chagas' cardiomyopathy and ventricular tachycardia treated with implantable cardioverter-defibrillators: commentary.

Europace 2019 Mar 21. Epub 2019 Mar 21.

Heart Institute (InCor) - Pacameker Clinic - University of São Paulo Medical School, Av. Eneas de Carvalho Aguiar, São Paulo, SP, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz045DOI Listing
March 2019
2 Reads

Remote monitoring of implantable cardioverter-defibrillators and resynchronization devices to improve patient outcomes: dead end or way ahead?

Europace 2019 Mar 21. Epub 2019 Mar 21.

Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.

Remote monitoring (RM) has become a new standard of care in the follow-up of patients with implantable pacemakers and defibrillators. While it has been consistently shown that RM enables earlier detection of clinically actionable events compared with traditional in-patient evaluation, this advantage did not translate into improved patient outcomes in clinical trials of RM except one study using daily multiparameter telemonitoring in heart failure (HF) patients. Therefore, this review, focusing on RM studies of implantable cardioverter-defibrillators and cardiac resynchronization therapy defibrillators in patients with HF, discusses possible explanations for the differences in trial outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz011DOI Listing
March 2019
2 Reads

Consider temporal aggressive rhythm control before ICD implantation in patients with heart failure with reduced ejection fraction.

Europace 2019 Mar 20. Epub 2019 Mar 20.

CARMA Center, University of Utah, 30 N 1900 E, RM 4A 100, Salt Lake City, UT, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz052DOI Listing
March 2019
2 Reads

Bidirectional ventricular tachycardia in ACTH-producing pheochromocytoma.

Europace 2019 Mar 20. Epub 2019 Mar 20.

Department of Endocrinology, Hospital de Braga, Braga, Portugal.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz043DOI Listing
March 2019
2 Reads

Improving first shock success in patients with atrial fibrillation undergoing electrical cardioversion.

Europace 2019 Mar 20. Epub 2019 Mar 20.

The Permanente Medical Group, Oakland, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz025DOI Listing

Improving first shock success in patients with atrial fibrillation undergoing electrical cardioversion: Authors' reply.

Europace 2019 Mar 20. Epub 2019 Mar 20.

Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, H-1285A, Ottawa, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz048DOI Listing

Prophylactic implantable cardioverter-defibrillator in the very elderly.

Europace 2019 Mar 19. Epub 2019 Mar 19.

Paris Cardiovascular Research Center, Paris, France.

Aims: Current guidelines do not propose any age cut-off for the primary prevention implantable cardioverter-defibrillator (ICD). However, the risk/benefit balance in the very elderly population has not been well studied.

Methods And Results: In a multicentre French study assessing patients implanted with an ICD for primary prevention, outcomes among patients aged ≥80 years were compared with <80 years old controls matched for sex and underlying heart disease (ischaemic and dilated cardiomyopathy). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz041DOI Listing
March 2019
4 Reads

Pulmonary vein-gap re-entrant atrial tachycardia following atrial fibrillation ablation: an electrophysiological insight with high-resolution mapping.

Europace 2019 Mar 19. Epub 2019 Mar 19.

Division of Cardiology, Department of Internal Medicine, The Jikei University School of Medicine, Nishishinbashi, Minato-ku, Tokyo, Japan.

Aims: The circuit of pulmonary vein-gap re-entrant atrial tachycardia (PV-gap RAT) after atrial fibrillation ablation is sometimes difficult to identify by conventional mapping. We analysed the detailed circuit and electrophysiological features of PV-gap RATs using a novel high-resolution mapping system.

Methods And Results: This multicentre study investigated 27 (7%) PV-gap RATs in 26 patients among 378 atrial tachycardias (ATs) mapped with Rhythmia™ system in 281 patients. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/europace/advance-article/doi/10.109
Publisher Site
http://dx.doi.org/10.1093/europace/euz034DOI Listing
March 2019
5 Reads

PREVEntion and regReSsive Effect of weight-loss and risk factor modification on Atrial Fibrillation: the REVERSE-AF study-Authors' reply.

Europace 2019 Mar 18. Epub 2019 Mar 18.

Department of Cardiology, Centre for Heart Rhythm Disorders, Royal Adelaide Hospital, University of Adelaide, Adelaide, SA, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz050DOI Listing

Spotlight on S-ICD™ therapy: 10 years of clinical experience and innovation.

Europace 2019 Mar 18. Epub 2019 Mar 18.

Division of Electrophysiology, Department of Cardiology and Angiology, University Hospital of Muenster, Muenster, Germany.

Subcutaneous ICD (S-ICD™) therapy has been established in initial clinical trials and current international guideline recommendations for patients without demand for pacing, cardiac resynchronization, or antitachycardia pacing. The promising experience in 'ideal' S-ICD™ candidates increasingly encourages physicians to provide the benefits of S-ICD™ therapy to patients in clinical constellations beyond 'classical' indications of S-ICD™ therapy, which has led to a broadening of S-ICD™ indications in many centres. However, the decision for S-ICD™ implantation is still not covered by controlled randomized trials but rather relies on patient series or observational studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz029DOI Listing
March 2019
2 Reads

Letter to the editor-pREVEntion and regReSsive Effect of weight-loss and risk factor modification on Atrial Fibrillation: the REVERSE-AF study.

Europace 2019 Mar 18. Epub 2019 Mar 18.

School of Biomedical Engineering & Imaging Sciences, King's College London, St. Thomas' Hospital, Westminster Bridge Road, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz023DOI Listing

Inadvertent transseptal puncture into the aortic root: the narrow edge between luck and catastrophe in interventional cardiology.

Europace 2019 Mar 18. Epub 2019 Mar 18.

Department of Cardiology, Asklepios Klinik St. Georg, Lohmühlenstr. 5, Hamburg, Germany.

Aims: Inadvertent puncture of the aortic root (AR) is a well-known complication of transseptal puncture (TSP). Strategies for handling of this potentially lethal complication have not been identified yet. In this study, we present typical anatomical locations and clinical management of aortic root puncture (ARP) due to TSP. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/europace/advance-article/doi/10.109
Publisher Site
http://dx.doi.org/10.1093/europace/euz042DOI Listing
March 2019
9 Reads

EHRA White Paper: knowledge gaps in arrhythmia management-status 2019.

Europace 2019 Mar 18. Epub 2019 Mar 18.

Antwerp University and Antwerp University Hospital, Antwerp, Belgium.

Clinicians accept that there are many unknowns when we make diagnostic and therapeutic decisions. Acceptance of uncertainty is essential for the pursuit of the profession: bedside decisions must often be made on the basis of incomplete evidence. Over the years, physicians sometimes even do not realize anymore which the fundamental gaps in our knowledge are. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz055DOI Listing
March 2019
1 Read

Management of asymptomatic arrhythmias: a European Heart Rhythm Association (EHRA) consensus document, endorsed by the Heart Failure Association (HFA), Heart Rhythm Society (HRS), Asia Pacific Heart Rhythm Society (APHRS), Cardiac Arrhythmia Society of Southern Africa (CASSA), and Latin America Heart Rhythm Society (LAHRS).

Europace 2019 Mar 18. Epub 2019 Mar 18.

Service de Cardiologie et Laboratoire d'Electrophysiologie Cardiaque, Centre Hospitalier Universitaire Trousseau et Université François Rabelais, Tours, France.

Asymptomatic arrhythmias are frequently encountered in clinical practice. Although studies specifically dedicated to these asymptomatic arrhythmias are lacking, many arrhythmias still require proper diagnostic and prognostic evaluation and treatment to avoid severe consequences, such as stroke or systemic emboli, heart failure, or sudden cardiac death. The present document reviews the evidence, where available, and attempts to reach a consensus, where evidence is insufficient or conflicting. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz046DOI Listing
March 2019
7 Reads

Brugada electrocardiogram pattern and right bundle branch block: Authors' reply.

Europace 2019 Mar 16. Epub 2019 Mar 16.

Department of Cardiology, Angiology and Intensive Care Medicine, University Heart Center Lübeck, Medical Clinic II, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz049DOI Listing

Epicardial ablation for ventricular tachycardia in Freidreich's ataxia cardiomyopathy.

Europace 2019 Mar 16. Epub 2019 Mar 16.

Department of Cardiology, Instituto de Investigación Sanitaria del, Hospital General Universitario Gregorio Marañón, CIBERCV and Hospital General Universitario Gregorio Marañón, C/Dr Esquerdo 46, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz030DOI Listing
March 2019
1 Read

Brugada electrocardiogram pattern and right bundle branch block.

Europace 2019 Mar 16. Epub 2019 Mar 16.

Department of Medicine, Division of Cardiology, Heart Rhythm Service, Queen's University, Kingston General Hospital, Kingston, Ontario, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz020DOI Listing

Adjacent multiple accessory pathways demonstrated on ultra-high-resolution mapping.

Europace 2019 Mar 16. Epub 2019 Mar 16.

Department of Cardiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz044DOI Listing

Pre- and post-treatment with amiodarone for elective electrical cardioversion of atrial fibrillation: a systematic review and meta-analysis.

Europace 2019 Mar 15. Epub 2019 Mar 15.

McMaster University, Hamilton, ON, Canada.

Clinicians pre-treat patients with amiodarone to increase the efficacy of electrical cardioversion for atrial fibrillation (AF). We conducted a systematic review and meta-analysis of randomized controlled trials comparing pre- and post-treatment for electrical cardioversion with amiodarone versus no therapy on (i) acute restoration and (ii) maintenance of sinus rhythm after 1 year. We searched MEDLINE and EMBASE from inception to July 2018. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy310DOI Listing
March 2019
1 Read

Corrigendum.

Authors:

Europace 2019 Mar 14. Epub 2019 Mar 14.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz039DOI Listing

Corrigendum.

Authors:

Europace 2019 Mar 14. Epub 2019 Mar 14.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz053DOI Listing

Antithrombotic treatment in patients with atrial fibrillation and acute coronary syndromes: results of the European Heart Rhythm Association survey.

Europace 2019 Mar 14. Epub 2019 Mar 14.

School of Medicine, Belgrade University; Cardiology Clinic, Clinical Center of Serbia, Belgrade, Serbia.

The management of an acute coronary syndrome (ACS) in a patient with existing atrial fibrillation (AF) often presents a management dilemma both in the acute phase and post-ACS, since the majority of AF patients will already be receiving oral anticoagulation (OAC) for stroke prevention and will require further antithrombotic treatment to reduce the risk of in-stent thrombosis or recurrent cardiac events. Current practice recommendations are based largely on consensus option as there is limited evidence from randomized controlled trials. Prior to the launch of the new European Heart Rhythm Association (EHRA) consensus document, a survey was undertaken to examine current clinical management of these patients across centres in Europe. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/europace/advance-article/doi/10.109
Publisher Site
http://dx.doi.org/10.1093/europace/euz033DOI Listing
March 2019
4 Reads

Reasons for hospitalization and risk of mortality in patients with atrial fibrillation treated with dabigatran or warfarin in the Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial.

Europace 2019 Mar 8. Epub 2019 Mar 8.

Department of Medicine, McMaster University, Population Health Research Institute (PHRI), 30 Birge St., Hamilton, Ontario L8L 0A6, Canada.

Aims: Hospitalizations are common among patients with atrial fibrillation. This article aimed to analyse the causes and consequences of hospitalizations occurring during the Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) trial.

Methods And Results: The RE-LY database was used to evaluate predictors of hospitalization using multivariate regression modelling. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz021DOI Listing
March 2019
3 Reads

Left pulmonary cusp ablation of refractory ventricular arrhythmia originating from the inaccessible summit.

Europace 2019 Mar 8. Epub 2019 Mar 8.

Department of Cardiology, Ordensklinikum Linz, Elisabethinen, Fadingerstr. 1, Linz A-4010, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz038DOI Listing
March 2019
2 Reads

QT as a predictor of recurrence after atrial fibrillation ablation and the impact of amiodarone: results from the placebo-controlled AMIO-CAT trial.

Europace 2019 Mar 6. Epub 2019 Mar 6.

Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, 2100 København, Denmark.

Aims: Prolonged corrected QT interval (QTc) might be associated with arrhythmia recurrence after atrial fibrillation (AF) ablation. The effect of short-term amiodarone in this setting remains unknown. This study seeks to quantify short-term amiodarone's impact on QTc, and to investigate QTc and amiodarone treatment as predictors of recurrence of arrhythmia after ablation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz028DOI Listing
March 2019
3 Reads

Sex differences in rate and rhythm control for atrial fibrillation.

Europace 2019 Mar 6. Epub 2019 Mar 6.

Department of Cardiology, Rijnstate Hospital Arnhem, Arnhem, The Netherlands.

Atrial fibrillation (AF), is the most common sustained arrhythmia and is associated with a substantial increase in morbidity and mortality. Several studies have demonstrated sex-related differences in various aspects, including age at diagnosis, clinical manifestations, management and prognosis. These dissimilarities may dictate different approaches to management and could translate to differences in outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy295DOI Listing
March 2019
2 Reads

Predictors of atrial ectopy and their relationship to atrial fibrillation risk.

Europace 2019 Mar 6. Epub 2019 Mar 6.

Division of Cardiology, Electrophysiology Section, University of California, San Francisco, 505 Parnassus Avenue, M-1180B, Box 0124, San Francisco, CA 94143-0124, USA.

Aims: Premature atrial contractions (PACs) are known to trigger and predict atrial fibrillation (AF). We sought to identify the determinants of PACs and the degree to which PACs mediate the effects of established risk factors for AF.

Methods And Results: Predictors of baseline PAC frequency were examined using a Holter Study among 1392 participants in the Cardiovascular Health Study, a community-based cohort of individuals aged ≥65 years. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/europace/advance-article/doi/10.109
Publisher Site
http://dx.doi.org/10.1093/europace/euz008DOI Listing
March 2019
7 Reads

Half a century of continuous pacing: a living witness to the evolution of a technology.

Europace 2019 Apr;21(4):548-553

Cardiology Clinical Academic Group, St. George's University Hospitals NHS Foundation Trust, Blackshaw Road, Tooting, London, UK.

To chart the development of pacing technology and its pitfalls we present the experience of a patient who has benefitted from it but also suffered as a result of it from its earliest days. A 53-year-old physician was referred to us with obstruction of the superior and inferior vena cava on a background of more than 50 years of continuous ventricular pacing and 24 previous pacemaker-related interventions. In a single surgical procedure, his existing pacing system and redundant leads were extracted, the superior vena cava was reconstructed, and a new biventricular pacing system with epicardial leads was implanted. Read More

View Article

Download full-text PDF

Source
https://academic.oup.com/europace/advance-article/doi/10.109
Publisher Site
http://dx.doi.org/10.1093/europace/euy218DOI Listing
April 2019
9 Reads

Recessive variants in plakophilin-2 contributes to early-onset arrhythmogenic cardiomyopathy with severe heart failure.

Europace 2019 Mar 4. Epub 2019 Mar 4.

State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Chinese Academy of Medical Science, 167 Beilishi Road, Xicheng District, Beijing, China.

Aims: Plakophilin-2 (PKP2) is the most prevalent mutant gene causing arrhythmogenic cardiomyopathy (ACM) and PKP2 carriers are prone to develop ventricular arrhythmic events. The objective of this study is to use integrated analysis of whole genome sequencing (WGS) and transcriptome sequencing (RNAseq) to identify deep intronic and/or coding variants that cause aberrant splicing events in ACM patients, and hence, to test the hypothesis that recessive variants in PKP2 may lead to early-onset ACM with severe heart failure.

Methods And Results: We performed WGS and RNAseq in 27 heart transplanted ACM patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz026DOI Listing
March 2019
1 Read

Predictors of mortality and heart transplantation in patients with Chagas' cardiomyopathy and ventricular tachycardia treated with implantable cardioverter-defibrillators.

Europace 2019 Feb 28. Epub 2019 Feb 28.

Clinical Medicine Area, Cardiology/Cardiovascular Laboratory, Faculty of Medicine, University of Brasilia, Brasília, Brazil.

Aims: Data on long-term follow-up of patients with Chagas' heart disease (ChHD) receiving a secondary prevention implantable cardioverter-defibrillator (ICD) are limited and its benefit is controversial. The aim of this study was to evaluate the long-term outcomes of ChHD patients who received a secondary prevention ICD.

Methods And Results: We assessed the outcomes of consecutive ChHD patients referred to our Institution from 2006 to 2014 for a secondary prevention ICD [89 patients; 58 men; mean age 56 ± 11 years; left ventricular ejection fraction (LVEF), 42 ± 12%]. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz012DOI Listing
February 2019
1 Read

Ventricular conduction stability test: a method to identify and quantify changes in whole heart activation patterns during physiological stress.

Europace 2019 Feb 28. Epub 2019 Feb 28.

National Heart & Lung Institute, Imperial College London, London, UK.

Aims: Abnormal rate adaptation of the action potential is proarrhythmic but is difficult to measure with current electro-anatomical mapping techniques. We developed a method to rapidly quantify spatial discordance in whole heart activation in response to rate cycle length changes. We test the hypothesis that patients with underlying channelopathies or history of aborted sudden cardiac death (SCD) have a reduced capacity to maintain uniform activation following exercise. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz015DOI Listing
February 2019
1 Read

Acute safety, effectiveness, and real-world clinical usage of ultra-high density mapping for ablation of cardiac arrhythmias: results of the TRUE HD study.

Europace 2019 Apr;21(4):655-661

Heart Rhythm Centre, Royal Brompton and Harefield foundation Trust and Imperial College, London, UK.

Aims: The objective of this study was to verify acute safety, performance, and usage of a novel ultra-high density mapping system in patients undergoing ablation procedure in a real-world clinical setting.

Methods And Results: The TRUE HD study enrolled patients undergoing catheter ablation with mapping for all arrhythmias (excluding de novo atrial fibrillation) who were followed for 1 month. Safety was determined by collecting all serious adverse events and adverse events associated with the study devices. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452400PMC
April 2019
2 Reads

Therapy of ventricular arrhythmias in patients suffering from isolated left ventricular non-compaction cardiomyopathy.

Europace 2019 Feb 26. Epub 2019 Feb 26.

Department of Cardiology, Asklepios Klinik St. Georg, Hamburg, Germany.

Aims: Non-compaction cardiomyopathy (NCCM) is associated with high rates of mortality and morbidity. Knowledge regarding risk stratification, arrhythmogenesis, therapy, and prognosis is limited. The aim of this study was to analyse the outcome of patients suffering from NCCM and ventricular arrhythmias (VAs) focusing on a treatment with implantable cardioverter-defibrillator (ICD) therapy and catheter ablation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz016DOI Listing
February 2019
2 Reads

Decline in incidence of sudden cardiac death in the young: a 10-year nationwide study of 8756 deaths in Denmark.

Europace 2019 Feb 26. Epub 2019 Feb 26.

The Department of Cardiology, The Heart Centre, Copenhagen University Hospital, Rigshospitalet, Section 2142, Blegdamsvej 9, Copenhagen, Denmark.

Aims: Sudden cardiac death in the young (SCDY) accounts for a significant proportion of deaths among the young. The aim of this nationwide study was to examine temporal changes in incidence and causes of SCDY in Denmark in 2000-2009. During this 10-year period, several public and private health initiatives were undertaken to decrease morbidity and mortality in Denmark. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euz022DOI Listing
February 2019

Do 'difficult to identify' pulmonary vein connections explain continuing high recurrence rates after atrial fibrillation ablation?

Europace 2019 Jan;21(Supplement_1):i4-i11

Department of Cardiology and Cardiovascular Surgery, Clínica Universidad de Navarra, Avenida Pío XII, 36 Pamplona, Spain.

Despite the emerging technical evolution of the last two decades, the primary success rate of single-procedure pulmonary vein isolation (PVI), the cornerstone for any atrial fibrillation ablation procedure, is highly variable ranging from 53% to 92%. The recent development of ultra-high-density electroanatomic mapping systems, capable of acquiring and annotating multiple electrograms, with high spatiotemporal precision, which are processed by automated algorithms to generate activation and substrate maps to support and guide ablation procedures, has opened a new stage in cardiac electrophysiology. In this article, we review the existing evidence on the utility of high-density mapping on catheter-based PVI, the possibility to detect pulmonary vein potentials that remain undetected when using a standard approach and its potential relevance to the clinical outcome, and how this new technology is providing novel pathophysiological insights on complete PVI and atrial fibrillation ablation outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy177DOI Listing
January 2019
2 Reads

Scar identification, quantification, and characterization in complex atrial tachycardia: a path to targeted ablation?

Europace 2019 Jan;21(Supplement_1):i21-i26

Service de Cardiologie, Centre Hospitalier Princesse Grace, Avenue Pasteur, Monaco.

Successful catheter ablation of scar-related atrial tachycardia depends on correct identification of the critical isthmus. Often, this is a represented by a small bundle of viable conducting tissue within a low-voltage area. It's identification depends on the magnitude of the signal/noise ratio. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy182DOI Listing
January 2019
2 Reads

Pulmonary vein reconnections or substrate in the left atrium: what is the reason for atrial fibrillation recurrences? A dialogue on a pressing clinical situation.

Europace 2019 Jan;21(Supplement_1):i12-i20

Cardiology Department, University Hospital Southampton, National Health Service Foundation Trust, Southampton, UK.

Pulmonary vein isolation (PVI) has long been held as the cornerstone for atrial fibrillation (AF) ablation. There are patients who do not have successful AF ablations though, especially among those with persistent AF. At the same time, the evidence suggests that ablating beyond the pulmonary veins does not improve success rates. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy289DOI Listing
January 2019

Is it feasible to offer 'targeted ablation' of ventricular tachycardia circuits with better understanding of isthmus anatomy and conduction characteristics?

Europace 2019 Jan;21(Supplement_1):i27-i33

IHU Liryc, Electrophysiology and Heart Modeling Institute, fondation Bordeaux Université, F Pessac- Bordeaux, France.

Successful mapping and ablation of ventricular tachycardias remains a challenging clinical task. Whereas conventional entrainment and activation mapping was for many years the gold standard to identify reentrant circuits in ischaemic ventricular tachycardia ablation procedures, substrate mapping has become the cornerstone of ventricular tachycardia ablation. In the last decade, technology has dramatically improved. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy173DOI Listing
January 2019
1 Read
3.050 Impact Factor

An initial experience of high-density mapping-guided ablation in a cohort of patients with adult congenital heart disease.

Europace 2019 Jan;21(Supplement_1):i43-i53

Department of Cardiology, Royal Brompton and Harefield Hospital, Imperial College London, Sydney Street, SW3 6NP London, UK.

Aims: In the management of both ventricular and supraventricular tachycardia in patients with congenital heart disease (CHD) catheter ablation has now been recognized as one of the mainstays.

Methods And Results: We review our initial experience of using the Rhythmia mapping system in a cohort of 12 adult CHD patients presenting with multiple arrhythmia substrates. A total of 78 arrhythmia maps were attempted in a total of 15 procedures, but possible due to the dilatation of the target chamber only 44% of maps were able to reconstruct the entire arrhythmia. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388091PMC
January 2019
3 Reads

A novel assessment of local impedance during catheter ablation: initial experience in humans comparing local and generator measurements.

Europace 2019 Jan;21(Supplement_1):i34-i42

Department of Cardiac Electrophysiology, University Heart Center, University Hospital Hamburg Eppendorf, Martinistrasse 52, Hamburg, Germany.

Aims: A novel measure of local impedance (LI) has been found to predict lesion formation during radiofrequency current (RFC) catheter ablation. The aim of this study was to investigate the utility of this novel approach, while comparing LI to the well-established generator impedance (GI).

Methods And Results: In 25 consecutive patients with a history of atrial fibrillation, catheter ablation was guided by a 3D-mapping system measuring LI in addition to GI via an ablation catheter tip with three incorporated mini-electrodes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy273DOI Listing
January 2019
3 Reads

Advanced mapping capabilities 2018-summary: are we working towards more personalized ablation strategies?

Europace 2019 Jan;21(Supplement_1):i2-i3

Universitaetsklinikum Eppendorf, Martinistr. 52, Hamburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euy240DOI Listing
January 2019
1 Read