5,210 results match your criteria Europace[Journal]


Wearable cardioverter-defibrillator and ventricular arrhythmias: risk stratification in patients with shorter device use-Authors' reply.

Europace 2018 Dec 15. Epub 2018 Dec 15.

Department of Medicine, Cardiology Division, University of Rochester Medical Center, Clinical Cardiovascular Research Center, 265 Crittenden Blvd., Rochester, NY, USA.

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http://dx.doi.org/10.1093/europace/euy287DOI Listing
December 2018

Wearable cardioverter-defibrillator and ventricular arrhythmias: risk stratification in patients with shorter device use.

Europace 2018 Dec 15. Epub 2018 Dec 15.

Division of Cardiology, Kingston Health Sciences Center, Queen's University, Kingston, Ontario, Canada.

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http://dx.doi.org/10.1093/europace/euy283DOI Listing
December 2018

Postextrasystolic unmasking of Brugada electrocardiogram.

Europace 2018 Dec 17. Epub 2018 Dec 17.

Department of Electrophysiology, University Heart Center Lübeck, Medical Clinic II, University of Lübeck, Ratzeburger Allee 160, Lübeck, Germany.

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http://dx.doi.org/10.1093/europace/euy242DOI Listing
December 2018

Pacing parameters and success rates of permanent His-bundle pacing in patients with narrow QRS: a single-centre experience.

Europace 2018 Dec 15. Epub 2018 Dec 15.

Department of Cardiology, The Heart Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Aims: High and unstable capture thresholds affect the success rate of permanent His-bundle pacing (HBP). We aimed to introduce the modified techniques during different periods and the corresponding success rate of HBP implantation.

Methods And Results: Patients from a single centre who had intrinsic QRS < 120 ms and HBP attempts were included in the study. Read More

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http://dx.doi.org/10.1093/europace/euy281DOI Listing
December 2018

The challenges of implanted cardiac device security: lessons from recent compromises.

Europace 2018 Dec 12. Epub 2018 Dec 12.

Department of Clinical Cardiac Electrophysiology, Scripps Memorial Hospital, 9850 Genesee Avenue, Suite 940, La Jolla, USA.

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http://dx.doi.org/10.1093/europace/euy264DOI Listing
December 2018

Updated systematic review and meta-analysis of the impact of contact force sensing on the safety and efficacy of atrial fibrillation ablation: discrepancy between observational studies and randomized control trial data.

Europace 2018 Dec 13. Epub 2018 Dec 13.

Department of Cardiology, Westmead Hospital, Sydney, Australia.

Aims: Despite widespread adoption of contact force (CF) sensing technology in atrial fibrillation (AF) ablation, randomized data suggests lack of improvement in clinical outcomes. We aimed to assess the safety and efficacy of CF-guided vs. non CF-guided AF ablation. Read More

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http://dx.doi.org/10.1093/europace/euy266DOI Listing
December 2018

Evaluation of a novel cardioversion intervention for atrial fibrillation: the Ottawa AF cardioversion protocol.

Europace 2018 Dec 7. Epub 2018 Dec 7.

Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada.

Aims: Electrical cardioversion is commonly performed to restore sinus rhythm in patients with atrial fibrillation (AF), but it is unsuccessful in 10-12% of attempts. We sought to evaluate the effectiveness and safety of a novel cardioversion protocol for this arrhythmia.

Methods And Results: Consecutive elective cardioversion attempts for AF between October 2012 and July 2017 at a tertiary cardiovascular centre before (Phase I) and after (Phase II) implementing the Ottawa AF cardioversion protocol (OAFCP) as an institutional initiative in July 2015 were evaluated. Read More

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http://dx.doi.org/10.1093/europace/euy285DOI Listing
December 2018
2 Reads

Anatomical proximity dictates successful ablation from adjacent sites for outflow tract ventricular arrhythmias linked to the coronary venous system.

Europace 2018 Dec 10. Epub 2018 Dec 10.

Cardiac Electrophysiology Section, Cardiovascular Division, Hospital of University of Pennsylvania, 9 Founders Pavilion - Cardiology, 3400 Spruce St. Philadelphia, PA, USA.

Aims: Catheter ablation of outflow tract ventricular arrhythmias (OTVAs) with the earliest activation within the coronary venous system (CVS) can be challenging. When ablation from the CVS is not feasible or ineffective, an approach from anatomically adjacent site(s) can be considered. We report the outcomes of an anatomical approach for OTVAs linked to the CVS. Read More

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http://dx.doi.org/10.1093/europace/euy255DOI Listing
December 2018
1 Read

Survey on the research activities within the EHRA Young EP community.

Europace 2018 Dec 10. Epub 2018 Dec 10.

Department of Electrophysiology, Heart Center Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1093/europace/euy294DOI Listing
December 2018

Clinical outcome in patients with implantable cardioverter-defibrillator and cancer: a nationwide study.

Europace 2018 Dec 7. Epub 2018 Dec 7.

Department of Cardiology, Herlev-Gentofte University Hospitals, Kildegårdsvej 28, Copenhagen, 2900 Hellerup, Denmark.

Aims: Patients with cancer are insufficiently represented in randomized clinical trials investigating efficacy of implantable cardioverter-defibrillators (ICDs). We aimed to describe outcomes in patients with a pre-existing diagnosis of cancer at time of ICD implantation.

Methods And Results: We utilized Danish nationwide registries to identify primary and secondary prevention ICD implantations from 2007 to 2012. Read More

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http://dx.doi.org/10.1093/europace/euy268DOI Listing
December 2018

Cryoablation vs. radiofrequency for therapy of atrioventricular nodal re-entrant tachycardia.

Europace 2018 Nov 30. Epub 2018 Nov 30.

Hygeia Hospital, 4 Erythrou Stavrou Str, Athens 15123, Greece.

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http://dx.doi.org/10.1093/europace/euy249DOI Listing
November 2018
1 Read

Frequent premature atrial contractions are associated with atrial fibrillation, brain ischaemia, and mortality: a systematic review and meta-analysis.

Europace 2018 Dec 1. Epub 2018 Dec 1.

Department of General Practice, Amsterdam UMC, University of Amsterdam, Amsterdam Public Health, Academic Medical Center, Meibergdreef 9, AZ Amsterdam, Netherlands.

Aims: Premature atrial contractions (PACs) are a common cardiac phenomenon, traditionally considered to be of little clinical significance. Recent studies, however, suggest that PACs are associated with atrial fibrillation (AF), as well as ischaemic stroke, transient ischaemic attack, and mortality. This systematic review aims to investigate the association between PACs on standard electrocardiogram (ECG) as well as PAC-count on Holter monitor and future detection of AF, brain ischaemia, and all-cause mortality in patients without a history of AF. Read More

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https://academic.oup.com/europace/advance-article/doi/10.109
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http://dx.doi.org/10.1093/europace/euy276DOI Listing
December 2018
5 Reads

Optimization of coronary sinus lead placement targeted to right-to-left delay in patients undergoing cardiac resynchronization therapy.

Europace 2018 Nov 30. Epub 2018 Nov 30.

Arrhythmologic Center, Ospedali del Tigullio, Via Don Bobbio 24, 16033 Lavagna, Italy.

Aims: Anatomical placement of the coronary sinus (CS) lead in basal or mid-ventricular positions of the posterior and lateral walls is associated with a better clinical outcome of cardiac resynchronization therapy (CRT). We hypothesized that optimization of CS lead placement targeted the right-to-left electrical delay (RLD) predicts an additional clinical benefit.

Methods And Results: The CS lead was placed according to current standards in 90 patients (Conventional group) and at the site of the longest RLD in 121 patients (RLD group). Read More

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https://academic.oup.com/europace/advance-article/doi/10.109
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http://dx.doi.org/10.1093/europace/euy275DOI Listing
November 2018
3 Reads

The importance of time in therapeutic range in switching from vitamin K antagonist to non-vitamin K antagonist oral anticoagulants in atrial fibrillation.

Europace 2018 Dec 1. Epub 2018 Dec 1.

Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 3, København Ø, Denmark.

Aims: Patients with non-valvular atrial fibrillation (NVAF) receiving vitamin K antagonists (VKAs) with time in therapeutic international normalized ratio (INR) range (TTR) <70%, despite good adherence, are by guidelines recommended to switch to non-VKA oral anticoagulants (NOACs). The aim was to assess if patients are switched from VKA to NOAC when TTR is <70% in a real-world setting.

Methods And Results: Non-valvular atrial fibrillation patients receiving VKA (1 January 2010 to 31 December 2012) were identified in nationwide registries. Read More

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http://dx.doi.org/10.1093/europace/euy262DOI Listing
December 2018
1 Read

Predicting electrical storms by remote monitoring of implantable cardioverter-defibrillator patients using machine learning.

Europace 2018 Nov 30. Epub 2018 Nov 30.

Department of Computer Science, University of Copenhagen, Universitetsparken 5, Copenhagen 2100, Denmark.

Aims: Electrical storm (ES) is a serious arrhythmic syndrome that is characterized by recurrent episodes of ventricular arrhythmias. Electrical storm is associated with increased mortality and morbidity despite the use of implantable cardioverter-defibrillators (ICDs). Predicting ES could be essential; however, models for predicting this event have never been developed. Read More

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http://dx.doi.org/10.1093/europace/euy257DOI Listing
November 2018

Public-access automated external defibrillation and bystander-initiated cardiopulmonary resuscitation in schools: a nationwide investigation in Japan.

Europace 2018 Nov 29. Epub 2018 Nov 29.

Division of Environmental Medicine and Population Sciences, Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University, 2-2 Yamada-Oka, Suita 565-0871, Japan.

Aims: We aimed to reveal the effects of application of public-access automated external defibrillators (AEDs) and bystander-initiated cardiopulmonary resuscitation (CPR) on survival of paediatric patients with out-of-hospital cardiac arrest (OHCA) occurring on school campuses in Japan.

Methods And Results: Data were obtained from a nationwide prospective observational study of paediatric OHCAs in school settings in Japan, termed Stop and Prevent cardIac aRrest, Injury, and Trauma in Schools (SPIRITS). Non-traumatic OHCA patients from elementary school, junior high school, and high school/technical college between April 2008 and December 2015 were enrolled. Read More

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http://dx.doi.org/10.1093/europace/euy261DOI Listing
November 2018
2 Reads

Prolonged action potential duration and dynamic transmural action potential duration heterogeneity underlie vulnerability to ventricular tachycardia in patients undergoing ventricular tachycardia ablation.

Europace 2018 Nov 29. Epub 2018 Nov 29.

Department of Cardiac Electrophysiology, The Barts Heart Center, St Bartholomew's Hospital, West Smithfield, London EC1A 7BE, UK.

Aims: Differences of action potential duration (APD) in regions of myocardial scar and their borderzones are poorly defined in the intact human heart. Heterogeneities in APD may play an important role in the generation of ventricular tachycardia (VT) by creating regions of functional block. We aimed to investigate the transmural and planar differences of APD in patients admitted for VT ablation. Read More

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http://dx.doi.org/10.1093/europace/euy260DOI Listing
November 2018
1 Read

To continue or minimally interrupt direct oral anticoagulants around ablation for atrial fibrillation: that is the question.

Authors:
David H Birnie

Europace 2018 Nov 28. Epub 2018 Nov 28.

Division of Cardiology, University of Ottawa Heart Institute, 40 Ruskin Street, Ottawa, Ontario, Canada.

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https://academic.oup.com/europace/advance-article/doi/10.109
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http://dx.doi.org/10.1093/europace/euy278DOI Listing
November 2018

Atrial fibrillation: the era of scientific breakthrough.

Europace 2018 Nov;20(FI_3):f275-f277

Division of Cardiac and Vascular Sciences, Molecular and Clinical Sciences Research Institute, St George's University of London, London, UK.

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http://dx.doi.org/10.1093/europace/euy279DOI Listing
November 2018

Ventricular substrate identification using close-coupled paced electrogram feature analysis.

Europace 2018 Nov 26. Epub 2018 Nov 26.

Heart Rhythm Service, Queen's University, Armstrong 3, Kingston Health Sciences Centre, 76 Stuart Street, Kingston, Ontario, Canada.

Aims: Substrate based catheter ablation strategies are widely employed for treatment of scar-related ventricular tachycardia (VT). We analysed intracardiac electrograms (EGMs) from close-coupled paced extrastimuli extracted from the EnSite Precision mapping system. We sought to characterize EGM responses of ventricular myocardium to varying coupling intervals from the right ventricular apex (RVA) in both healthy individuals and patients presenting with VT for catheter ablation. Read More

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https://academic.oup.com/europace/advance-article/doi/10.109
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http://dx.doi.org/10.1093/europace/euy265DOI Listing
November 2018
6 Reads

Current status of interventional cardiac electrophysiology training in ESC member countries: an EHRA Young EP Report.

Europace 2018 Nov 26. Epub 2018 Nov 26.

Semmelweis University, Budapest, Hungary, and University of Rochester Medical Center, Rochester, NY,USA.

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http://dx.doi.org/10.1093/europace/euy277DOI Listing
November 2018

9th Theo Rossi di Montelera forum on computer simulation and experimental assessment of cardiac function: from model to clinical outcome.

Europace 2018 Nov;20(suppl_3):iii1-iii2

Center for Computational Medicine in Cardiology, Università della Svizzera Italiana, Lugano, Switzerland.

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http://dx.doi.org/10.1093/europace/euy256DOI Listing
November 2018

Bioinformatic analysis of a plakophilin-2-dependent transcription network: implications for the mechanisms of arrhythmogenic right ventricular cardiomyopathy in humans and in boxer dogs.

Europace 2018 Nov;20(suppl_3):iii125-iii132

The Leon H Charney Division of Cardiology, New York University School of Medicine, 435 East 30th Street. SB 707, New York, NY, USA.

Aims: Previous studies in murine hearts and in cell systems have shown that modifications in the expression or sequence integrity of the desmosomal molecule plakophilin-2 (PKP2) can alter the downstream expression of transcripts necessary for the electrical and mechanical function of the heart. These findings have provided support to mechanistic hypotheses that seek to explain arrhythmogenic right ventricular cardiomyopathy (ARVC) in humans. However, the relation between PKP2 expression and the transcriptome of the human heart remains poorly explored. Read More

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http://dx.doi.org/10.1093/europace/euy238DOI Listing
November 2018
1 Read

Species differences in the morphology of transverse tubule openings in cardiomyocytes.

Europace 2018 Nov;20(suppl_3):iii120-iii124

Institute for Experimental Cardiovascular Medicine, University Heart Center, Faculty of Medicine, University of Freiburg, Elsässerstraße 2Q, Freiburg, Germany.

Aims: The ultrastructure of ventricular cardiomyocyte T-tubule connections with the outer cell surface ('mouth' regions) has been reported to differ between mice and rabbits. In mice, T-tubule mouths form convoluted narrow spaces filled with electron-dense matter that impedes diffusion between T-tubular lumen and bulk extracellular space. Here, we explore whether T-tubule mouths are also constricted in rat (another murine model used frequently for cardiac research) and whether pig and human T-tubule mouth configurations are structurally more similar to mice or rabbits. Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/europace/euy245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251183PMC
November 2018
3 Reads

Support vector machine-based assessment of the T-wave morphology improves long QT syndrome diagnosis.

Europace 2018 Nov;20(suppl_3):iii113-iii119

Department of Biomedical Engineering, Maastricht University, PO Box 616, 6200 MD Maastricht, The Netherlands.

Aims: Diagnosing long QT syndrome (LQTS) is challenging due to a considerable overlap of the QTc-interval between LQTS patients and healthy controls. The aim of this study was to investigate the added value of T-wave morphology markers obtained from 12-lead electrocardiograms (ECGs) in diagnosing LQTS in a large cohort of gene-positive LQTS patients and gene-negative family members using a support vector machine.

Methods And Results: A retrospective study was performed including 688 digital 12-lead ECGs recorded from genotype-positive LQTS patients and genotype-negative relatives at their first visit. Read More

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https://academic.oup.com/europace/article/20/suppl_3/iii113/
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http://dx.doi.org/10.1093/europace/euy243DOI Listing
November 2018
2 Reads

Effect of Na+-channel blockade on the three-dimensional substrate of atrial fibrillation in a model of endo-epicardial dissociation and transmural conduction.

Europace 2018 Nov;20(suppl_3):iii69-iii76

Department of Physiology, Maastricht University, Universiteitssingel 50, ER, Maastricht, The Netherlands.

Aims: Atrial fibrillation (AF) is a progressive arrhythmia characterized by structural alterations that increase its stability. Both clinical and experimental studies showed a concomitant loss of antiarrhythmic drug efficacy in later stages of AF. The mechanisms underlying this loss of efficacy are not well understood. Read More

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http://dx.doi.org/10.1093/europace/euy236DOI Listing
November 2018
2 Reads

Influence of left atrial size on P-wave morphology: differential effects of dilation and hypertrophy.

Europace 2018 Nov;20(suppl_3):iii36-iii44

Institute of Biomedical Engineering, Karlsruhe Institute of Technology (KIT), Kaiserstr. 12, Karlsruhe, Germany.

Aims: Chronic left atrial enlargement (LAE) increases the risk of atrial fibrillation. Electrocardiogram (ECG) criteria might provide a means to diagnose LAE and identify patients at risk; however, current criteria perform poorly. We seek to characterize the potentially differential effects of atrial dilation vs. Read More

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http://dx.doi.org/10.1093/europace/euy231DOI Listing
November 2018

Simulated P wave morphology in the presence of endo-epicardial activation delay.

Europace 2018 Nov;20(suppl_3):iii16-iii25

Département de Pharmacologie et Physiologie, Institut de Génie Biomédical, Université de Montréal, Montréal, QC, Canada.

Aims: Evidences of asynchrony between epicardial and endocardial activation in the atrial wall have been reported. We used a computer model of the atria and torso to investigate the consequences of such activation delay on P wave morphology, while controlling for P wave duration.

Methods And Results: We created 390 models of the atria based on the same geometry. Read More

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http://dx.doi.org/10.1093/europace/euy229DOI Listing
November 2018
1 Read

Determinants of new wavefront locations in cholinergic atrial fibrillation.

Europace 2018 Nov;20(suppl_3):iii3-iii15

LIRYC Electrophysiology and Heart Modeling Institute, Bordeaux Fondation, Avenue du Haut-Lévèque, Pessac, France.

Aims: Atrial fibrillation (AF) wavefront dynamics are complex and difficult to interpret, contributing to uncertainty about the mechanisms that maintain AF. We aimed to investigate the interplay between rotors, wavelets, and focal sources during fibrillation.

Methods And Results: Arrhythmia wavefront dynamics were analysed for four optically mapped canine cholinergic AF preparations. Read More

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http://dx.doi.org/10.1093/europace/euy235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251188PMC
November 2018
1 Read

Fast personalized electrophysiological models from computed tomography images for ventricular tachycardia ablation planning.

Europace 2018 Nov;20(suppl_3):iii94-iii101

Université Côte d'Azur, Inria, Epione, Sophia Antipolis, France.

Aims: Clinical application of patient-specific cardiac computer models requires fast and robust processing pipelines that can be seamlessly integrated into clinical workflows. We aim at building such a pipeline from computed tomography (CT) images to personalized cardiac electrophysiology (EP) model. The simulation output could be useful in the context of post-infarct ventricular tachycardia (VT) radiofrequency ablation (RFA) planning for pre-operative targets prediction. Read More

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https://academic.oup.com/europace/article/20/suppl_3/iii94/5
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http://dx.doi.org/10.1093/europace/euy228DOI Listing
November 2018
3 Reads

Patient-specific simulations predict efficacy of ablation of interatrial connections for treatment of persistent atrial fibrillation.

Europace 2018 Nov;20(suppl_3):iii55-iii68

School of Biomedical Engineering & Imaging Sciences, King's College London, St. Thomas' Hospital, Westminster Bridge Road, UK.

Aims: Treatments for persistent atrial fibrillation (AF) offer limited efficacy. One potential strategy aims to return the right atrium (RA) to sinus rhythm (SR) by ablating interatrial connections (IAC) to isolate the atria, but there is limited clinical data to evaluate this ablation approach. We aimed to use simulation to evaluate and predict patient-specific suitability for ablation of IAC to treat AF. Read More

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http://dx.doi.org/10.1093/europace/euy232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251187PMC
November 2018
1 Read

A left bundle branch block activation sequence and ventricular pacing influence voltage amplitudes: an in vivo and in silico study.

Europace 2018 Nov;20(suppl_3):iii77-iii86

Center for Computational Medicine in Cardiology (CCMC), Institute of Computational Science, Università della Svizzera italiana, Lugano, Switzerland.

Aims: The aim of this study was to investigate the influence of the activation sequence on voltage amplitudes by evaluating regional voltage differences during a left bundle branch block (LBBB) activation sequence vs. a normal synchronous activation sequence and by evaluating pacing-induced voltage differences.

Methods And Results: Twenty-one patients and three computer models without scar were studied. Read More

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http://dx.doi.org/10.1093/europace/euy233DOI Listing
November 2018

Arrhythmia dynamics in computational models of the atria following virtual ablation of re-entrant drivers.

Europace 2018 Nov;20(suppl_3):iii45-iii54

Institute for Computational Medicine and Department of Biomedical Engineering, Johns Hopkins University, 3400 N. Charles St, 208 Hackerman Hall, Baltimore, MD, USA.

Aims: Efforts to improve ablation success rates in persistent atrial fibrillation (AF) patients by targeting re-entrant driver (RD) sites have been hindered by weak mechanistic understanding regarding emergent RDs localization following initial fibrotic substrate modification. This study aimed to systematically assess arrhythmia dynamics after virtual ablation of RD sites in computational models.

Methods And Results: Simulations were conducted in 12 patient-specific atrial models reconstructed from pre-procedure late gadolinium-enhanced magnetic resonance imaging scans. Read More

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http://dx.doi.org/10.1093/europace/euy234DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251184PMC
November 2018

Beat-to-beat P-wave morphological variability in patients with paroxysmal atrial fibrillation: an in silico study.

Europace 2018 Nov;20(suppl_3):iii26-iii35

Center for Computational Medicine in Cardiology, Università della Svizzera italiana, Lugano, Switzerland.

Aims: P-wave beat-to-beat morphological variability can identify patients prone to paroxysmal atrial fibrillation (AF). To date, no computational study has been carried out to mechanistically explain such finding. The aim of this study was to provide a pathophysiological explanation, by using a computer model of the human atria, of the correlation between P-wave beat-to-beat variability and the risk of AF. Read More

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http://dx.doi.org/10.1093/europace/euy227DOI Listing
November 2018
2 Reads

Electrocardiogram phenotypes in hypertrophic cardiomyopathy caused by distinct mechanisms: apico-basal repolarization gradients vs. Purkinje-myocardial coupling abnormalities.

Europace 2018 Nov;20(suppl_3):iii102-iii112

Department of Computer Science, University of Oxford, Wolfson Building, Parks Rd, Oxford, UK.

Aims: To identify key structural and electrophysiological features explaining distinct electrocardiogram (ECG) phenotypes in hypertrophic cardiomyopathy (HCM).

Methods And Results: Human heart-torso anatomical models were constructed from cardiac magnetic resonance (CMR) images of HCM patients, representative of ECG phenotypes identified previously. High performance computing simulations using bidomain models were conducted to dissect key features explaining the ECG phenotypes with increased HCM Risk-SCD scores, namely Group 1A, characterized by normal QRS but inverted T waves laterally and coexistence of apical and septal hypertrophy; and Group 3 with marked QRS abnormalities (deep and wide S waves laterally) and septal hypertrophy. Read More

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http://dx.doi.org/10.1093/europace/euy226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251182PMC
November 2018
1 Read

Linking cross-bridge cycling kinetics to response to cardiac resynchronization therapy: a multiscale modelling study.

Europace 2018 Nov;20(suppl_3):iii87-iii93

Department of Biomedical Engineering, CARIM School for Cardiovascular Diseases, Maastricht University Medical Center, Maastricht University, Universiteitssingel 50., P.O. Box 616, ER Maastricht, The Netherlands.

Aims: Cardiac resynchronization therapy (CRT) is currently the most widely used treatment for heart failure patients with left bundle branch block (LBBB). In recent years, the presence of septal rebound stretch (SRS) has been found to be a positive indicator for CRT response although the mechanism is unknown.

Methods And Results: In an attempt to understand the relation between cellular mechanics and global pump function in CRT patients, we utilize the CircAdapt closed-loop cardiovascular system model in combination with the MechChem model of cardiac sarcomere contraction. Read More

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http://dx.doi.org/10.1093/europace/euy230DOI Listing
November 2018
1 Read

Chylothorax and chylopericardium as unusual manifestation of pacing lead related complication.

Europace 2018 Nov 23. Epub 2018 Nov 23.

Department of Cardiology, Medical University, Lublin, Poland.

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http://dx.doi.org/10.1093/europace/euy269DOI Listing
November 2018

Edoxaban and implantable cardiac device interventions: insights from the ENGAGE AF-TIMI 48 trial.

Europace 2018 Nov 19. Epub 2018 Nov 19.

Cardiovascular Division, TIMI Study Group, Brigham and Women's Hospital, 350 Longwood Avenue, 1st Floor Offices, Boston, MA, USA.

Aims: Pacemaker, implantable cardioverter-defibrillator, and cardiac resynchronization therapy device implantations and generator changes are frequently performed in patients receiving direct oral anticoagulants. In an exploratory analysis, we investigated the outcome of patients undergoing such device procedures in the ENGAGE AF-TIMI 48 trial.

Methods And Results: During the trial, 1217 device procedures were performed in 1145 patients, with intervention dates available for 1203 procedures. Read More

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http://dx.doi.org/10.1093/europace/euy253DOI Listing
November 2018
4 Reads

Atrial fibrillation burden, progression, and the risk of death: a case-crossover analysis in patients with cardiac implantable electronic devices.

Europace 2018 Nov 19. Epub 2018 Nov 19.

Cleveland Clinic, Cleveland, OH, USA.

Aims: Atrial fibrillation (AF) is associated with increased mortality, but the temporal relationship between AF burden (AFB) and death among patients with cardiac implanted electronic devices is unknown. We sought to characterize the timing and progression of AFB before death.

Methods And Results: Using Merlin. Read More

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http://dx.doi.org/10.1093/europace/euy222DOI Listing
November 2018
10 Reads

Comparison of electrocardiogram characteristics and pacing parameters between left bundle branch pacing and right ventricular pacing in patients receiving pacemaker therapy.

Europace 2018 Nov 20. Epub 2018 Nov 20.

State Key Laboratory of Cardiovascular Disease, Arrhythmia Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.

Aims: This study explores the feasibility of left bundle branch pacing (LBBP) and characterizes electrocardiogram (ECG) patterns during the pacing in comparison with conventional right ventricular pacing (RVP).

Methods And Results: Forty pacing-indicated patients were prospectively enrolled. Twenty patients underwent LBBP (the LBBP group), and 20 patients underwent RVP (the RVP group). Read More

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http://dx.doi.org/10.1093/europace/euy252DOI Listing
November 2018
7 Reads

Cryoablation with an 8-mm tip catheter cryoablation in the treatment of atrioventricular nodal re-entrant tachycardia: results from a randomized controlled trial (CRYOABLATE).

Europace 2018 Nov 20. Epub 2018 Nov 20.

Department of Internal Medicine, National Taiwan University Hospital, Taiwan.

Aims: This was a randomized controlled study performed to compare 8 mm-tip catheter cryoablation (CRYO) with radiofrequency ablation (RFA) in treating atrioventricular nodal re-entrant tachycardia (AVNRT).

Methods And Results: A total of 158 patients (103 women, mean age 48.9 ± 14. Read More

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http://dx.doi.org/10.1093/europace/euy225DOI Listing
November 2018
4 Reads

Electroanatomical delimitation of recipient atrium in heart transplantation.

Europace 2018 Nov 19. Epub 2018 Nov 19.

Cardiology Department, University Hospital 12 de Octubre, Avenida de Cordoba SN, Madrid, Spain.

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http://dx.doi.org/10.1093/europace/euy258DOI Listing
November 2018
2 Reads

Leadless pacemakers: learning from experience-Authors' reply.

Europace 2018 Nov 16. Epub 2018 Nov 16.

Cardiology Department, University Hospital of Geneva, Rue Gabrielle Perret Gentil 4, Geneva, Switzerland.

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http://dx.doi.org/10.1093/europace/euy270DOI Listing
November 2018

Leadless pacemakers: learning from experience.

Authors:
Nicolas Clementy

Europace 2018 Nov 16. Epub 2018 Nov 16.

Cardiology Department, Trousseau Hospital, University of Tours, Service de Cardiologie, Hôpital Trousseau, CHRU de Tours, Tours, France.

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http://dx.doi.org/10.1093/europace/euy248DOI Listing
November 2018

Leadless pacing using the transcatheter pacing system (Micra TPS) in the real world: initial Swiss experience from the Romandie region.

Europace 2018 Nov 16. Epub 2018 Nov 16.

Department of Cardiovascular Sciences, University of Leuven, Herestraat 49, Leuven, Belgium.

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http://dx.doi.org/10.1093/europace/euy272DOI Listing
November 2018

Super-response to cardiac resynchronization therapy reduces appropriate implantable cardioverter-defibrillator therapy: comment-Authors' reply.

Europace 2018 Nov 13. Epub 2018 Nov 13.

Division of Heart Rhythm Services, Department of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN, USA.

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http://dx.doi.org/10.1093/europace/euy244DOI Listing
November 2018

Super-response to cardiac resynchronization therapy reduces appropriate implantable cardioverter-defibrillator therapy: comment.

Europace 2018 Nov 13. Epub 2018 Nov 13.

Department of Cardiology, University Medical Centre Ljubljana, Zaloška 7, Ljubljana, Slovenia.

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http://dx.doi.org/10.1093/europace/euy211DOI Listing
November 2018

Reducing right ventricular pacing burden: algorithms, benefits, and risks.

Europace 2018 Nov 13. Epub 2018 Nov 13.

Lenon H. Charney Devision of Cardiology, Cardiac Electrophysiology, NYU Langone Health, New York University School of Medicine, NY, USA.

Algorithms designed to reduce the burden of right ventricular pacing are widely available in modern implantable pacing devices. To ensure safe and optimal utilization, understanding the properties of these algorithms as well as their possible unfavourable effects is essential. In this review, we discuss in detail the technical and clinical aspects of rhythm management algorithms and update on their significant recent modifications. Read More

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http://dx.doi.org/10.1093/europace/euy263DOI Listing
November 2018
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A case of focal ventricular tachycardia with alternating endocardial and epicardial exits: utility of non-invasive mapping in predicting exits.

Europace 2018 Nov 13. Epub 2018 Nov 13.

Lenox Hill Hospital, Department of Cardiology, 100 East 77th Street, New York, NY, USA.

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http://dx.doi.org/10.1093/europace/euy241DOI Listing
November 2018
1 Read