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J Obstet Gynaecol 2019 Apr 25:1-8. Epub 2019 Apr 25.

c Department of Radiology , Federal Teaching Hospital , Abakaliki , Nigeria.

Fetal weight estimation is important in the management of labour and delivery. This study aimed to compare the accuracy of the clinical and ultrasound methods of fetal weight estimation. This was a prospective study involving 110 term cephalic singleton pregnancies delivered within 24 hours of clinical fetal weight estimation using Johnson's and Dare's formulae and ultrasound estimation at a Tertiary hospital in Abakaliki, Nigeria. Read More

J Obstet Gynaecol 2019 Apr 22:1-7. Epub 2019 Apr 22.

a Department of ObGyn. Private Practice , Ankara , Turkey.

The aim of this study was to assess the accuracy of a new formula for the calculation of an estimated fetal weight (EFW) and to evaluate value of fetal visceral adipose tissue (VAT) and abdominal subcutaneous fat (SF) thickness on the prediction of birth weight. In this prospective study, fetal biometry, EFW, fetal VAT and SF thickness were measured in low-risk 37-41 gestational weeks pregnant women by ultrasonography. The linear regression analysis was performed to investigate the relationship between birth weight and obstetric measurements. Read More

BMC Pregnancy Childbirth 2019 Apr 11;19(1):122. Epub 2019 Apr 11.

Department of Obstetrics and Gynaecology, Division of Obstetrics and Fetomaternal Medicine, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria.

Background: Fetal weight estimation is of key importance in the decision-making process for obstetric planning and management. The literature is inconsistent on the accuracy of measurements with either ultrasound or clinical examination, known as Leopold's manoeuvres, shortly before term. Maternal BMI is a confounding factor because it is associated with both the fetal weight and the accuracy of fetal weight estimation. Read More

Biomed Res Int 2019 10;2019:7576934. Epub 2019 Mar 10.

Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100026, China.

Objective: A retrospective study was performed to evaluate the safety and feasibility of cesarean myomectomy among pregnant women with uterine fibroids (UFs).

Methods: Upon data collection, the pregnant women with UF underwent cesarean section in the 39 hospital divided into two groups: cesarean myomectomy group, receiving cesarean section and myomectomy; cesarean group, receiving cesarean section only. Information about the type, location, and number of UFs was collected from the medical records or the prenatal ultrasound examinations. Read More

BMJ Open 2019 Mar 27;9(3):e027160. Epub 2019 Mar 27.

Department of Obstetrics and Gynecology, University Hospital Brugmann, Université Libre de Bruxelles, Brussels, Belgium.

Introduction: Macrosomia refers to growth beyond a specific threshold, regardless of gestational age. These fetuses are also frequently referred to as large for gestational age (LGA). Various cut-offs have been used but for research purposes, a cut-off above the 95th centile for birth weight is often preferred because it defines 90% of the population as normal weight. Read More

Taiwan J Obstet Gynecol 2019 Mar;58(2):278-281

Department of Obstetrics and Perinatology, Jagiellonian University Medical College, Cracow, Poland.

Objective: Ultrasound estimation of foetal weight is a very important aspect of antenatal care. The role of amniotic fluid volume as a potential factor which may impede the relevance of ultrasonographic foetal weight estimation is still questionable. The aim of our study was to evaluate the impact of isolated oligohydramnios on the accuracy of ultrasound foetal weight estimation in at term pregnancies when examination was performed within 48 h before delivery. Read More

Taiwan J Obstet Gynecol 2019 Mar;58(2):273-277

Department of Obstetrics and Gynaecology, United Christian Hospital, Hong Kong.

Objective: A new ultrasound formula for fetal weight estimation was proposed from the INTERGROWTH-21 project in 2017. There is no comparison of its accuracy with other ultrasound formulae. This study aims to compare the accuracy of INTERGROWTH-21 formula in fetal weight estimation with the traditional Hadlock1 and Shepard formula. Read More

Pak J Med Sci 2019 Jan-Feb;35(1):34-38

Prof. Ayse Filiz Yavuz, Department of Obstetrics and Gynecology, Ankara Yildirim Beyazit University, Faculty of Medicine, Ankara, Turkey.

Objectives: To investigate the factors which might influence the sonographic fetal weight estimation (SFWE) accuracy.

Methods: This prospective study was conducted among 949 singleton term pregnant women who delivered at a tertiary center, from January 2017 to December 2017. All participants' maternal (i. Read More

J Pregnancy 2019 3;2019:8540637. Epub 2019 Feb 3.

Study Program of Mathematics, Faculty of Mathematics and Natural Sciences, University of Lambung Mangkurat (ULM), Ahmad Yani Street, Km. 36, Banjarbaru, South Kalimantan 70714, Indonesia.

Objectives: To assess the impact of scientific and technical training on midwives' abilities in collecting and recording the key performance indicators for fetal growth chart development in limited-resource settings.

Methods: A descriptive design was used to describe midwives' abilities in timely collecting and recording the minimum data required to estimate fetal weight and develop fetal growth chart. The study was conducted among 19 urban and rural midwives in South Kalimantan, Indonesia, between April 2016 and October 2017. Read More

Am J Obstet Gynecol 2019 Feb 18. Epub 2019 Feb 18.

Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.

Background: Amniotic fluid is essential to normal fetal development and is estimated clinically with ultrasound scanning to identify pregnancies that are at risk for poor perinatal outcome.

Objective: Our goal was to develop a United States standard for amniotic fluid volume that is estimated by the amniotic fluid index and single deepest pocket.

Study Design: We performed a planned secondary analysis of a multicenter observational study of 2334 low-risk women with normal singleton gestations from 1 of 4 self-reported racial/ethnic groups. Read More

Enferm Clin 2019 03 4;29 Suppl 1:98-100. Epub 2019 Feb 4.

Public Health Service (Puskesmas) Pagar Dewa, West Lampung, Province of Lampung, Indonesia.

Objective: To know the relation between estimation of fetal weight with hemoglobin levels during pregnancy at Public Health Service (Puskesmas) Pagar Dewa-West Lampung, Province of Lampung.

Method: Quantitative research type with cross sectional approach. The population in this study was all pregnant women at West Lampung area with a number of 70 respondents as total sampling technique. Read More

J Matern Fetal Neonatal Med 2019 Jan 6:1-5. Epub 2019 Jan 6.

c Kuczkowski Foundation Global Initiative , La Jolla , CA , USA.

Background: The accurate identification of an intervertebral lumbar level is essential to avoid neuraxial anesthesia and analgesia-related spinal cord injury. It has been shown that estimation of L3/4 intervertebral lumbar level based on the intercristal line determined by palpation (palpated L3/4) is often inaccurate. However; studies evaluating intervertebral lumbar level concordance based on palpation vs. Read More

Eur J Radiol 2019 Jan 7;110:242-248. Epub 2018 Dec 7.

Department of Obstetrics and Gynaecology, NanFang Hospital, Southern Medical University, Guangzhou, China. Electronic address:

Purpose: To determine whether birth weight can be reliably estimated using three-dimensional (3D) magnetic resonance imaging (MRI) foetal body volume at term.

Method: Foetuses between 37 weeks and 41 weeks of gestation were delivered within 7 days after MRI and ultrasound (US) examinations. 3D foetal models were reconstructed from MRI data, and body volume was calculated. Read More

Am J Obstet Gynecol 2018 Dec 22. Epub 2018 Dec 22.

Department of Obstetrics and Gynecology, University Hospital Brugmann, Université Libre de Bruxelles, Brussels, Belgium. Electronic address:

Fetuses at the extremes of growth abnormalities carry a risk of perinatal morbidity and death. Their identification traditionally is done by 2-dimensional ultrasound imaging, the performance of which is not always optimal. Magnetic resonance imaging superbly depicts fetal anatomy and anomalies and has contributed largely to the evaluation of high-risk pregnancies. Read More

BJOG 2018 Dec 21. Epub 2018 Dec 21.

Institute for Women's Health, University College London, London, UK.

Objective: To determine whether a novel therapy for placental insufficiency could achieve orphan drug status by estimating the annual incidence of placental insufficiency, defined as an estimated fetal weight below the 10th centile in the presence of abnormal umbilical artery Doppler velocimetry, per 10 000 European Union (EU) population as part of an application for European Medicines Agency (EMA) orphan designation.

Design: Incidence estimation based on literature review and published national and EU statistics.

Setting And Population: European Union. Read More

Arch Gynecol Obstet 2019 Feb 18;299(2):459-468. Epub 2018 Dec 18.

Obstetrics and Gynecology Hospital, Fudan University, 419 Fangxie Road, Shanghai, 200011, China.

Purpose: To investigate the value of ultrasound approaching delivery to predict isolated inter-twin discordance and adverse perinatal outcomes.

Methods: We retrospectively included twin pregnancies with sonography approaching delivery in ten maternal-foetal medicine centres in China from 2013 to 2014. Estimated foetal weight (EFW) and inter-twin EFW disparity (EFWD) were calculated based on biometry parameters. Read More

Chemosphere 2019 Mar 28;219:655-661. Epub 2018 Nov 28.

Key Laboratory of Environment and Health, Ministry of Education & Ministry of Protection, and State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. Electronic address:

Benzophenones (BPs) are widely used as ultraviolet absorbers and fragrance retention agents. Evidences from animal studies have suggested that exposure to BPs may affect fetal growth, but human data is limited and no study is concerning critical windows of BPs exposure throughout pregnancy in relation to fetal growth. We aimed to investigate the associations of prenatal exposure to BPs with birth size and examine the critical exposure windows of fetus development. Read More

J Matern Fetal Neonatal Med 2019 Feb 3:1-10. Epub 2019 Feb 3.

b Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology , Sunnybrook Health Sciences Center, and University of Toronto , Toronto , Canada.

Objective: Twin fetus growth is delayed during the third trimester compared to singletons. Whether this phenomenon should be considered a normal physiologic characteristic of twins or a pathologic process inherent to twin pregnancies is currently unclear. Information on the growth rate of the individual fetal biometric indices may provide more insight into the mechanisms underlying these differences between twins and singletons. Read More

Br J Nutr 2019 Feb 16;121(3):285-290. Epub 2018 Nov 16.

3Department of Obstetrics and Gynecology,Maternal Infant Research Institute,Tufts Medical Center,800 Washington Street,Box 394,Boston,MA 02111,USA.

Newborn adiposity, a nutritional measure of the maternal-fetal intra-uterine environment, is representative of future metabolic health. An anthropometric model using weight, length and flank skinfold to estimate neonatal fat mass has been used in numerous epidemiological studies. Air displacement plethysmography (ADP), a non-invasive technology to measure body composition, is impractical for large epidemiological studies. Read More

BMC Pregnancy Childbirth 2018 Nov 6;18(1):436. Epub 2018 Nov 6.

School of Science (Mathematical and Geospatial Sciences), College of Science, Engineering, and Health, RMIT University, GPO BOX 2476, Melbourne, VIC, 3001, Australia.

Background: Birth weight is one of the most important indicators of neonatal survival. A reliable estimate of foetal weight at different stages of pregnancy would facilitate intervention plans for medical practitioners to prevent the risk of low birth weight delivery. This study has developed reliable models to more accurately predict estimated foetal weight at a given gestation age in the absence of ultrasound facilities. Read More

Arch Gynecol Obstet 2019 Jan 16;299(1):97-103. Epub 2018 Oct 16.

Hillel Yaffe Medical Center, Hadera, Israel.

Purpose: To evaluate the best performing formula for macrosomia prediction in pregnancies complicated by diabetes.

Methods: A retrospective analysis was performed of 1060 sonographic fetal biometrical measurements performed within 7 days of delivery in term pregnancies (37-42 gestational weeks) complicated by diabetes. Sonographic prediction of macrosomia (≥ 4000, ≥ 4250, and ≥ 4500 g) was evaluated utilizing ten previously published formulas by: (1) calculating for each macrosomia threshold the sensitivity, specificity, positive and negative predictive value, and ± likelihood ratio for macrosomia prediction; (2) comparing the systematic and random error and the proportion of estimates < 10% of birth weights between macrosomic and non-macrosomic neonates. Read More

Hum Reprod 2018 11;33(11):2141-2149

Department of Reproductive Medicine, KK Women's and Children's Hospital, Singapore, Singapore.

Study Question: Are higher overall and central adiposity associated with reduced fecundability, measured by time-to-pregnancy (TTP), in Asian women?

Summary Answer: Higher overall adiposity, but not central adiposity, was associated with longer TTP in Asian women.

What Is Known Already: High body mass index (BMI) has been associated with a longer TTP, although the associations of body composition and distribution with TTP are less clear. There are no previous studies of TTP in Asian women, who have a relatively higher percentage of body fat and abdominal fat at relatively lower BMI. Read More

Arch Gynecol Obstet 2018 Dec 4;298(6):1101-1106. Epub 2018 Oct 4.

Department of Gynecology, Obstetrics, and Gynecological Endocrinology, Kepler University Hospital, Johannes Kepler University, Altenberger Straße 69, 4040, Linz, Austria.

Purpose: Sonographic fetal weight (FW) estimation to detect macrosomic fetuses is an essential part of everyday routine work in obstetrics departments. Most of the commonly used weight estimation formulas underestimate FW when the actual birth weight (BW) exceeds 4000 g. One of the best-established weight estimation formulas is the Hadlock formula. Read More

Ultraschall Med 2018 Sep 25. Epub 2018 Sep 25.

Lis Maternity and Women's Hospital, Tel-Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Purpose:  To evaluate labor and perinatal outcomes of transient isolated polyhydramnios.

Materials And Methods:  A retrospective cohort study (2008 - 2013) at a university-affiliated, tertiary medical center. Eligibility was limited to patients with singleton gestations, no maternal diabetes or known structural/chromosomal anomalies, and no rupture of the membranes prior to delivery, at > 34 weeks of gestation. Read More

Rev Bras Ginecol Obstet 2018 Oct 20;40(10):580-586. Epub 2018 Sep 20.

Diagnostic Center, Clínica Perinatal Laranjeiras, Rio de Janeiro, RJ, Brazil.

Objective:  To assess 11 formulae commonly used to estimate fetal weight in a population of premature fetuses who had abnormal Doppler velocimetry due to early-onset placental insufficiency. The performance of each formula was evaluated in subgroups of fetuses with expected growth and intrauterine growth restriction.

Methods:  Data were collected from fetuses and mothers who delivered at three Brazilian hospitals between November 2002 and December 2013. Read More

Environ Int 2018 11 28;120:535-543. Epub 2018 Aug 28.

Dept of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Dept of Health Sciences, Karlstad University, Karlstad, Sweden.

Fundamental to regulatory guidelines is to identify chemicals that are implicated with adverse human health effects and inform public health risk assessors about "acceptable ranges" of such environmental exposures (e.g., from consumer products and pesticides). Read More

J Matern Fetal Neonatal Med 2018 Sep 19:1-7. Epub 2018 Sep 19.

a Maternal-Fetal Medicine Division, Obstetrics & Gynecology Department , Sainte-Justine University Hospital , Montreal , Canada.

Rationale: It is known that fetal growth is usually proportional to left-sided cardiac output (CO), which parallels the right-sided CO and that congenital right-sided lesions are usually associated with better perinatal outcomes than left-sided lesions.

Objective: Our objective was to document whether newborns from mothers with severe residual pulmonary valve insufficiency (PI) after surgical tetralogy of Fallot (TOF) or pulmonary valve stenosis (PS) correction have lower birth weight (BW) than newborns from mothers with absent, mild, or moderate PI.

Methods: This is a retrospective cohort study of women affected with repaired TOF and corrected PS with varied severity of residual PI. Read More

Am J Obstet Gynecol 2018 Nov 14;219(5):476.e1-476.e12. Epub 2018 Aug 14.

National Institute of Health and Medical Research Unité Mixte de Recherche 1153, Obstetrical, Perinatal, and Pediatric Epidemiology Research Team, Center for Epidemiology and Biostatistics, Paris-Descartes University, Paris, France.

Background: Accurate estimation of fetal weight is needed for growth monitoring and decision-making in obstetrics; the INTERGROWTH project developed an estimated fetal weight formula to construct new intrauterine growth standards.

Objective: We sought to compare the accuracy of the Hadlock and INTERGROWTH formulas for the estimation of fetal weight among preterm infants.

Study Design: Using the EPIPAGE 2 population-based study of births between 22-34 weeks of gestation, we included 578 nonanomalous singleton fetuses with an ultrasound-to-delivery interval <2 days. Read More

J Med Ultrasound 2017 Oct-Dec;25(4):201-207. Epub 2017 Aug 31.

Philips Research India, Philips Innovation Campus, Manyata Tech-Park, Nagavara, Bengaluru, Karnataka, 560045, India.

Background: The purpose of this study was to systematically evaluate ultrasound-based fetal weight estimation models on Indian population to find out their performance across different weight bands and ability to correctly categorize low birth weight (LBW) and high birth weight (HBW) fetuses.

Methods: We used retrospectively collected data of 154 cases for the study. Inclusion criteria were a live singleton pregnancy, gestational age ≥34 weeks and ultrasound scan to delivery duration ≤7 days. Read More

Environ Int 2018 11 29;120:54-62. Epub 2018 Jul 29.

Key Laboratory of Environment and Health, Ministry of Education, Ministry of Environmental Protection, State Key Laboratory of Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. Electronic address:

Background: Triclosan (TCS) is known to possess endocrine disrupting properties and metabolize rapidly in the human body. Human data concerning repeated measurements of TCS throughout pregnancy in relation to fetal and childhood growth are sparse.

Objectives: We investigated the associations between multiple measurements of maternal urinary concentrations of TCS during pregnancy and fetal and early-childhood growth. Read More

Ultrasonography 2019 Jan 14;38(1):50-57. Epub 2018 Apr 14.

Philips Research India, Philips Innovation Campus, Bengaluru, India.

Purpose: Existing ultrasound-based fetal weight estimation models have been shown to have high errors when used in the Indian population. Therefore, the primary objective of this study was to develop Indian population-based models for fetal weight estimation, and the secondary objective was to compare their performance against established models.

Methods: Retrospectively collected data from 173 cases were used in this study. Read More

Ultrasound Obstet Gynecol 2018 07;52(1):5-8

Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's University of London, London, UK.

Indian J Endocrinol Metab 2018 Mar-Apr;22(2):212-216

Department of Endocrinology, Gauhati Medical College, Guwahati, Assam, India.

Context: The neonatal skeletal outcomes due to maternal Vitamin D deficiency.

Aims: The aim of this study is to assess the serum 25 hydroxy Vitamin D (25[OH]D) status in pregnant women and correlate with cord blood 25(OH)D levels, femur length at 34 weeks gestation, and neonatal anthropometry (birth weight, birth length, and head circumference).

Settings And Design: This was prospective cohort study. Read More

Front Neurol 2018 28;9:91. Epub 2018 May 28.

MOE - Shanghai Key Laboratory of Children's Environmental Health, Shanghai Jiao Tong University School of Medicine, Xinhua Hospital, Shanghai, China.

Background: Due to the high prevalence in pregnant women and potential association with pregnancy complications or perinatal outcomes, sleep-disordered breathing (SDB) has become an increasing concern.

Methods: Pubmed and Embase were retrieved from inception until 2017 to conduct a meta-analysis to explore the association of SDB and several outcomes during gestation. A stratified analysis differentiated by the type of SDB [snoring alone/obstructive sleep apnea (OSA)] was also performed. Read More

J Ultrason 2018 Mar 30;18(72):50-55. Epub 2018 Mar 30.

Department of Obstetrics, Gynecology and Oncology, Second Faculty of Medicine, Medical University of Warsaw, Warsaw, Poland.

Ultrasonography, with its detailed imaging of the fetus, is very widely used in obstetrics. The primary aim of ultrasound scanning in pregnancy is to limit the risk of obstetric complications by early detection of abnormalities, such as intrauterine growth restriction and macrosomia. Currently, morphometric formulae are used for estimating fetal weight. Read More

Eur J Clin Nutr 2018 05 2;72(5):645-656. Epub 2018 May 2.

Reproductive Endocrinology and Women's Health, Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA, 70808, USA.

The prevalence of excess gestational weight gain is increasing worldwide and is associated with pregnancy complications, including gestational diabetes mellitus, pre-eclampsia, preterm birth, macrosomia, and development of obesity in offspring. Whereas gestational weight gain positively correlates with the gain in fat mass (FM), fat-free mass (FFM) gain is relatively consistent across pregnancies. Commonly used methods to assess body composition include anthropometry, densitometry (air displacement plethysmography, underwater weighing), and hydrometry (isotope dilution, bioimpedance analysis). Read More

BMC Pregnancy Childbirth 2018 May 2;18(1):118. Epub 2018 May 2.

Department of Obstetrics and Gynecology, University of Rostock, Suedring 81, 18059, Rostock, Germany.

Background: The aim of the study was to investigate the accuracy of ultrasound-derived estimated fetal weight (EFW) and to determine its impact on management and outcome of delivery.

Methods: In this single-center cohort analysis, women with a singleton term pregnancy in the beginning stages of labor were included. Women with immediately antepartum EFW (N = 492) were compared to women without ultrasound (N = 515). Read More

Aust N Z J Obstet Gynaecol 2018 Dec 27;58(6):674-680. Epub 2018 Apr 27.

Faculty of Medicine, University of Melbourne, Melbourne, Victoria, Australia.

Background: Severe fetal growth restriction (FGR) is a leading cause of adverse perinatal morbidity and mortality; however, in Victoria, 35% of severely growth-restricted infants are undelivered by 40 weeks gestation.

Aims: We aimed to identify factors associated with failure to deliver severely growth-restricted fetuses by 40 weeks gestation.

Methods: We conducted a retrospective case-control study of term singletons born <3rd centile for gestation at a single tertiary centre (2010-2017). Read More

J Gynecol Obstet Hum Reprod 2018 Oct 20;47(8):391-395. Epub 2018 Apr 20.

Department of Obstetrics and Gynecology, Turku University Hospital and University of Turku, Turku, Finland.

Objective: To assess the effect of an additional single mid-luteal dose of gonadotropin-releasing hormone agonist (GnRHa) on pregnancy and perinatal outcomes in hormonally substituted frozen embryo transfer (FET) cycles.

Study Design: A prospective interventional pilot study. Women scheduled for FET were randomly selected to receive standard hormonal replacement therapy (HRT) for endometrial preparation or HRT with a single additional subcutaneous dose of 0. Read More

Ultrasound Obstet Gynecol 2018 07 3;52(1):35-43. Epub 2018 Jun 3.

Department of Fetal Medicine, King's College Hospital, London, UK.

Objectives: To develop a new formula for ultrasonographic estimation of fetal weight and evaluate the accuracy of this and all previous formulae in the prediction of birth weight.

Methods: The study population consisted of 5163 singleton pregnancies with fetal biometry at 22-43 weeks' gestation and live birth of a phenotypically normal neonate within 2 days of the ultrasound examination. Multivariable fractional polynomial analysis was used to determine the combination of variables that provided the best-fitting models for estimated fetal weight (EFW). Read More

J Matern Fetal Neonatal Med 2018 Apr 18:1-9. Epub 2018 Apr 18.

a School of Information Engineering , Dalian University , Dalian , China.

Fetal weight is an important factor to determine the delivery mode of pregnant women. The change of fetal weight is significant, according to regular health monitoring of pregnant women. Conventional methods of fetal weight estimation, namely those based on B-ultrasound, are very complicated and the costs are high. Read More

Arch Gynecol Obstet 2018 Jun 17;297(6):1441-1447. Epub 2018 Mar 17.

Clinical Division of Gynecologic Endocrinology and Reproductive Medicine, Department of Obstetrics and Gynecology, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.

Purpose: To review our experience in ultrasound fetal weight estimation in our large population of triplet pregnancies.

Methods: Ninety-seven triplet pregnancies were retrospectively included between January 2003 and January 2017. Sonographic fetal weight estimation using Hadlock's and Schild's formulas was compared to actual birth weight in a tertiary-care center in Vienna, Austria. Read More

Ultrasound 2018 Feb 7;26(1):32-41. Epub 2018 Feb 7.

2University of Leeds, Leeds, UK.

Ultrasound estimation of fetal weight is a highly influential factor in antenatal management, guiding both the timing and mode of delivery of a pregnancy. Although substantial research has investigated the most accurate ultrasound formula for calculating estimated fetal weight, current evidence indicates significant error levels. The aim of this systematic review was to identify the most accurate method, whilst identifying sources of inaccuracy in order to facilitate recommendations for future practice. Read More

Biometrics 2018 09 13;74(3):910-923. Epub 2018 Feb 13.

School of Statistics, University of Minnesota, Minneapolis, Minnesota 55455, U.S.A.

The problem of estimating the average treatment effects is important when evaluating the effectiveness of medical treatments or social intervention policies. Most of the existing methods for estimating the average treatment effect rely on some parametric assumptions about the propensity score model or the outcome regression model one way or the other. In reality, both models are prone to misspecification, which can have undue influence on the estimated average treatment effect. Read More

Am J Obstet Gynecol 2018 Feb;218(2S):S700-S711.e1

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Fetal growth restriction implies failure of a fetus to meet its growth potential and is associated with increased perinatal mortality and morbidity. Therefore, antenatal detection of fetal growth restriction is of major importance in an attempt to deliver improved clinical outcomes. The most commonly used approach towards screening for fetal growth restriction is by means of sonographic fetal weight estimation, to detect fetuses small for gestational age, defined by an estimated fetal weight <10th percentile for gestational age. Read More

J Matern Fetal Neonatal Med 2019 Jul 15;32(14):2361-2368. Epub 2018 Feb 15.

a Fetal Medicine Unit , St. George's Hospital, St. George's University of London , London , UK.

Objective: Small for gestational age (SGA) fetuses are at increased risk of admission to the neonatal unit, even at term. We aimed to develop and validate a predictive model for the risk of prolonged neonatal unit admission in suspected SGA fetuses at term.

Methods: A single-center cohort study of singleton pregnancies with SGA fetus, defined as estimated fetal weight (EFW) less than the 10th centile, at term. Read More

J Matern Fetal Neonatal Med 2019 Jun 31;32(12):1992-1996. Epub 2018 Jan 31.

c Department of Obstetrics & Gynaecology , JIPMER , Puducherry , India.

Introduction: Gestational impaired glucose tolerance (GIGT) is a milder form of gestational diabetes mellitus (GDM), which is often poorly managed. Although, GDM is known to be associated with increased incidence of thyroid dysfunction, no study has been done to study the effect of GIGT on thyroid status and its effect on fetal outcome. Here, we carried out a study to assess thyroid function and glycemic status in both maternal and cord blood of the subjects with GIGT, and to find their association with the fetal outcome. Read More

Am J Perinatol 2018 Nov 10;35(13):1235-1240. Epub 2018 Jan 10.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Hofstra Northwell School of Medicine, North Shore University Hospital, Manhasset, New York.

Objective:  The objective of this study was to determine the effect, if any, of maternal body mass index (BMI) and amniotic fluid index (AFI) on the accuracy of sonographic estimated fetal weight (EFW) at 40 to 42 weeks' gestation.

Methods:  This was a retrospective cohort study of singleton gestations with ultrasound performed at 40 to 42 weeks from 2010 to 2013. In this study, patients with documented BMI and sonographic EFW and AFI, concurrently, within 7 days of delivery were included. Read More

Pediatrics 2018 02 4;141(2). Epub 2018 Jan 4.

Nuffield Department of Obstetrics & Gynaecology and Oxford Maternal & Perinatal Health Institute, Green Templeton College and.

There is no consensus regarding how the growth of preterm infants should be monitored or what constitutes their ideal pattern of growth, especially after term-corrected age. The concept that the growth of preterm infants should match that of healthy fetuses is not substantiated by data and, in practice, is seldom attained, particularly for very preterm infants. Hence, by hospital discharge, many preterm infants are classified as postnatal growth-restricted. Read More

Malar J 2017 Dec 18;16(1):491. Epub 2017 Dec 18.

Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Old Road Campus, Roosevelt Drive, Oxford, OX3 7FZ, UK.

Background: Considering the uncertainty of safety of anti-malarial drugs in pregnancy, efficacy studies are one of the few sources of clinical safety data. Complete safety evaluation is not usually incorporated in efficacy studies due to financial and human resource constraints. This review reports the methods used for the assessment of safety of artemisinin-based and quinine-based treatments in efficacy studies in pregnancy. Read More