11 results match your criteria Essentials of Tissue Movement

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Tissue factor variants induce monocyte transformation and transdifferentiation into endothelial cell-like cells.

J Thromb Haemost 2017 Aug 10;15(8):1689-1703. Epub 2017 Jul 10.

Cardiovascular Science Institute-ICCC, Hospital de Sant Pau (UAB) and IIB-Sant Pau, Barcelona, Spain.

Essentials Monocytes (Mo) transdifferentiate into endothelial cell-like (ECL) cells. Mo induce tissue factor (TF) expression and secretion in microvascular endothelial cells (mECs). TF interacts with Mo in a paracrine fashion, inducing their transdifferentiation into ECL cells. Read More

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Recombinant soluble apyrase APT102 inhibits thrombosis and intimal hyperplasia in vein grafts without adversely affecting hemostasis or re-endothelialization.

J Thromb Haemost 2017 04 23;15(4):814-825. Epub 2017 Feb 23.

Departments of Medicine and Medical Pharmacology and Physiology, University of Missouri School of Medicine and the Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO, USA.

Essentials New strategies are needed to inhibit thrombosis and intimal hyperplasia (IH) in vein grafts (VG). We studied effects of apyrase (APT102) on VGs and smooth muscle and endothelial cells (SMC/EC). APT102 inhibited thrombosis, SMC migration, and IH without impairing hemostasis or EC recovery. Read More

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Factor VII-activating protease deficiency promotes neointima formation by enhancing leukocyte accumulation.

J Thromb Haemost 2016 10 7;14(10):2058-2067. Epub 2016 Sep 7.

Department of Biochemistry, Justus-Liebig-Universität Giessen, Giessen, Germany.

Essentials Factor VII-activating protease (FSAP) is a plasma protease involved in vascular processes. Neointima formation was investigated after vascular injury in FSAP mice. The neointimal lesion size and the accumulation of macrophages were increased in FSAP mice. Read More

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October 2016
4 Reads

Physiologic variations in blood plasminogen levels affect outcomes after acute cerebral thromboembolism in mice: a pathophysiologic role for microvascular thrombosis.

J Thromb Haemost 2016 09 6;14(9):1822-32. Epub 2016 Aug 6.

Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.

Unlabelled: Essentials Physiologic variations in blood plasminogen (Pg) levels may affect ischemic stroke outcomes. We tested Pg effects in a model with translational relevance to human thromboembolic stroke. A dose-response exists between Pg levels and brain injury, fibrinolysis, barrier breakdown. Read More

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September 2016
1 Read

Extracellular histones reduce survival and angiogenic responses of late outgrowth progenitor and mature endothelial cells.

J Thromb Haemost 2016 Feb 4;14(2):397-410. Epub 2016 Feb 4.

Experimental Thrombosis Laboratory, Institute of Experimental Medicine (IMEX), National Academy of Medicine-CONICET, Buenos Aires, Argentina.

Unlabelled: ESSENTIALS: Extracellular histones are highly augmented in sites of neovessel formation, such as regeneration tissues. We studied histone effect on survival and angiogenic activity of mature and progenitor endothelial cells. Extracellular histones trigger apoptosis and pyroptosis and reduce angiogenesis in vivo and in vitro. Read More

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February 2016

Implicit Partitioned Cardiovascular Fluid-Structure Interaction of the Heart Cycle Using Non-newtonian Fluid Properties and Orthotropic Material Behavior.

Cardiovasc Eng Technol 2015 Mar 17;6(1):8-18. Epub 2014 Dec 17.

Institute of Fluid Mechanics, Karlsruhe Institute of Technology, KIT, Kaiserstr. 10, building 10.23, 76131, Karlsruhe, Germany.

Although image-based methods like MRI are well-developed, numerical simulation can help to understand human heart function. This function results from a complex interplay of biochemistry, structural mechanics, and blood flow. The complexity of the entire system often causes one of the three parts to be neglected, which limits the truth to reality of the reduced model. Read More

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March 2015
1 Read

Filling in the gaps before clients fall through the cracks: physiotherapists have the skills to help clients preserve bone and prevent falls.

Authors:
Meena M Sran

Physiother Can 2011 10;63(3):261-4. Epub 2011 Aug 10.

Meena M. Sran, PT, PhD: Osteoporosis Program, BC Women's Hospital & Health Centre; Movement Essentials Physiotherapy, Vancouver, BC.

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April 2016
1 Read

Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo.

Am J Pathol 2003 Aug;163(2):753-62

Laboratories of Molecular Pathology and Ultrastructure and Immunology, Regina Elena Cancer Institute, and the Molecular Biology and Pathology Institute, Consiglio Nazionale delle Ricerche, Rome, Italy.

Endothelin-1 (ET-1) and its receptors are overexpressed in human Kaposi's sarcoma lesions. Here we show that in human KS IMM cell line ET-1 increased secretion and activation of matrix-metalloproteinase-2 (MMP-2), -3, -7, -9 and -13, as well as of membrane-type 1-MMP (MT1-MMP). ET-1 and ET-3 also enhanced the expression of tissue inhibitor of MMP-2, essential for MT1-MMP-mediated MMP-2 activation. Read More

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August 2003
7 Reads

Fibrodysplasia ossificans progressiva: case report.

Arq Neuropsiquiatr 2000 Jun;58(2A):342-7

Department of Neurology, Faculty of Medicine, State University of Campinas (UNICAMP), SP, Brasil.

Fibrodysplasia ossificans progressiva is a rare genetic disease characterized by widespread soft tissue ossification and congenital stigmata of the extremities. We report on a male child followed for ten years since the age of 3 years and 9 months, when the diagnosis was made. He was born with bilateral hypoplasic hallux valgus and ventricular septal defect, corrected by trans-sternal approach when 32 months old. Read More

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June 2000
1 Read

Anterior patterning in mouse.

Trends Genet 1998 Jul;14(7):277-84

Division of Mammalian Development, MRC National Institute for Medical Research, Ridgeway, Mill Hill, London, UK.

The anteroposterior axis of the vertebrate embryo becomes explicit during gastrulation, the process that converts a relatively featureless embryonic precursor population into new tissues assembled into a recognisable body pattern. Vertebrate embryos arrive at gastrulation in very different states in terms of their size, cell number and reliance on factors inherited from the unfertilized egg. However, they emerge from gastrulation looking very similar, and there is now extensive molecular genetic evidence to indicate that the bare essentials of the gastrulation process have been well conserved during evolution. Read More

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July 1998
1 Read

Functional anatomy of the wrist.

Authors:
J M Kauer

Clin Orthop Relat Res 1980 Jun(149):9-20

The analysis of the carpal mechanism warrants detailed examination of the morphology of the wrist. Essentials of wrist morphology serve as a basis for the concept of the interdependent carpal articulation chains. In this concept the wrist joint functions with 3 parallel longitudinal chains. Read More

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June 1980
13 Reads
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