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    8 results match your criteria Essentials of Tissue Movement

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    Physiologic variations in blood plasminogen levels affect outcomes after acute cerebral thromboembolism in mice: a pathophysiologic role for microvascular thrombosis.
    J Thromb Haemost 2016 Sep 6;14(9):1822-32. Epub 2016 Aug 6.
    Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
    Unlabelled: Essentials Physiologic variations in blood plasminogen (Pg) levels may affect ischemic stroke outcomes. We tested Pg effects in a model with translational relevance to human thromboembolic stroke. A dose-response exists between Pg levels and brain injury, fibrinolysis, barrier breakdown. Read More

    Extracellular histones reduce survival and angiogenic responses of late outgrowth progenitor and mature endothelial cells.
    J Thromb Haemost 2016 Feb 4;14(2):397-410. Epub 2016 Feb 4.
    Experimental Thrombosis Laboratory, Institute of Experimental Medicine (IMEX), National Academy of Medicine-CONICET, Buenos Aires, Argentina.
    Unlabelled: ESSENTIALS: Extracellular histones are highly augmented in sites of neovessel formation, such as regeneration tissues. We studied histone effect on survival and angiogenic activity of mature and progenitor endothelial cells. Extracellular histones trigger apoptosis and pyroptosis and reduce angiogenesis in vivo and in vitro. Read More

    Implicit Partitioned Cardiovascular Fluid-Structure Interaction of the Heart Cycle Using Non-newtonian Fluid Properties and Orthotropic Material Behavior.
    Cardiovasc Eng Technol 2015 Mar 17;6(1):8-18. Epub 2014 Dec 17.
    Institute of Fluid Mechanics, Karlsruhe Institute of Technology, KIT, Kaiserstr. 10, building 10.23, 76131, Karlsruhe, Germany.
    Although image-based methods like MRI are well-developed, numerical simulation can help to understand human heart function. This function results from a complex interplay of biochemistry, structural mechanics, and blood flow. The complexity of the entire system often causes one of the three parts to be neglected, which limits the truth to reality of the reduced model. Read More

    Endothelin receptor blockade inhibits molecular effectors of Kaposi's sarcoma cell invasion and tumor growth in vivo.
    Am J Pathol 2003 Aug;163(2):753-62
    Laboratories of Molecular Pathology and Ultrastructure and Immunology, Regina Elena Cancer Institute, and the Molecular Biology and Pathology Institute, Consiglio Nazionale delle Ricerche, Rome, Italy.
    Endothelin-1 (ET-1) and its receptors are overexpressed in human Kaposi's sarcoma lesions. Here we show that in human KS IMM cell line ET-1 increased secretion and activation of matrix-metalloproteinase-2 (MMP-2), -3, -7, -9 and -13, as well as of membrane-type 1-MMP (MT1-MMP). ET-1 and ET-3 also enhanced the expression of tissue inhibitor of MMP-2, essential for MT1-MMP-mediated MMP-2 activation. Read More

    Fibrodysplasia ossificans progressiva: case report.
    Arq Neuropsiquiatr 2000 Jun;58(2A):342-7
    Department of Neurology, Faculty of Medicine, State University of Campinas (UNICAMP), SP, Brasil.
    Fibrodysplasia ossificans progressiva is a rare genetic disease characterized by widespread soft tissue ossification and congenital stigmata of the extremities. We report on a male child followed for ten years since the age of 3 years and 9 months, when the diagnosis was made. He was born with bilateral hypoplasic hallux valgus and ventricular septal defect, corrected by trans-sternal approach when 32 months old. Read More

    Anterior patterning in mouse.
    Trends Genet 1998 Jul;14(7):277-84
    Division of Mammalian Development, MRC National Institute for Medical Research, Ridgeway, Mill Hill, London, UK.
    The anteroposterior axis of the vertebrate embryo becomes explicit during gastrulation, the process that converts a relatively featureless embryonic precursor population into new tissues assembled into a recognisable body pattern. Vertebrate embryos arrive at gastrulation in very different states in terms of their size, cell number and reliance on factors inherited from the unfertilized egg. However, they emerge from gastrulation looking very similar, and there is now extensive molecular genetic evidence to indicate that the bare essentials of the gastrulation process have been well conserved during evolution. Read More

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