Physiologic variations in blood plasminogen levels affect outcomes after acute cerebral thromboembolism in mice: a pathophysiologic role for microvascular thrombosis.
J Thromb Haemost 2016 Sep 6;14(9):1822-32. Epub 2016 Aug 6.
Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Unlabelled: Essentials Physiologic variations in blood plasminogen (Pg) levels may affect ischemic stroke outcomes. We tested Pg effects in a model with translational relevance to human thromboembolic stroke. A dose-response exists between Pg levels and brain injury, fibrinolysis, barrier breakdown. Read More