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Eur Arch Otorhinolaryngol 2019 Feb 26. Epub 2019 Feb 26.

Department of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Philips van Leydenlaan 15, 6500 HB, Nijmegen, The Netherlands.

Purpose: Although office-based transnasal esophagoscopy has been investigated extensively, a cost analysis is still lacking. We performed a cost analysis combined with feasibility study for two diagnostic processes: patients with globus pharyngeus and/or dysphagia, and hypopharyngeal carcinoma.

Methods: Prospective cohort study. Read More

Clin Gastroenterol Hepatol 2019 Jan 29. Epub 2019 Jan 29.

Digestive Health Institute, Children's Hospital Colorado, Section of Pediatric Gastroenterology, Hepatology and Nutrition, University of Colorado School of Medicine; Aerodigestive Program, Children's Hospital Colorado.

Background & Aims: Evaluation and treatment of children with eosinophilic esophagitis (EoE) requires serial endoscopic, visual, and histologic assessment by sedated esophagogastroduodenoscopy (EGD). Unsedated transnasal endoscopy (TNE) was reported to be successful in a pilot study of children. We evaluated video goggle and virtual reality-based unsedated TNE in children with EoE, collecting data on rates of completion, adverse events, and adequacy of visual and histologic findings. Read More

Int Arch Otorhinolaryngol 2019 Jan 11;23(1):7-11. Epub 2018 Oct 11.

Department of ENT, Lancaster Royal Infirmary, Lancaster, United Kingdom of Great Britain and Northern Ireland.

 Transnasal esophagoscopy (TNE) is a widely used tool both in the diagnosis and treatment of patients presenting complaints within the head and the neck. This is because this investigative adjunct examination provides the advantage of visualizing above the level of the cricopharyngeus muscle when compared to the more widely used esophagogastroduodenoscopy (EGD).  We have assessed if the implementation of TNE within a district general hospital (DGH) was feasible, and investigated if the resources of our patients could be better directed away from other investigations such as barium swallow and EGD in favor of this novel technique. Read More

Laryngoscope 2018 Dec 13. Epub 2018 Dec 13.

Department of Otolaryngology-Head and Neck Surgery, Norfolk and Norwich University Hospital, Norwich, United Kingdom.

Objectives/hypothesis: To present yield of transnasal esophagoscopy (TNE) biopsies of upper aerodigestive tract (UADT) lesions and define the role of TNE as a safe alternative to rigid endoscopy.

Study Design: Retrospective case series.

Methods: All patients who underwent TNE-guided biopsies attempted over a 2-year period were included. Read More

J Pediatr Gastroenterol Nutr 2018 Oct 12. Epub 2018 Oct 12.

Digestive Health Institute, Section of Pediatric Gastroenterology, Hepatology and Nutrition, Children's Hospital Colorado, Aurora, CO, United States.

Thorac Surg Clin 2018 Nov;28(4):453-464

Esophageal and Lung Institute, Allegheny Health Network, Western Pennsylvania Hospital, Suite 158, Mellon Pavilion, 4815 Liberty Avenue, Pittsburgh, PA 15224, USA. Electronic address:

In Western countries, the incidence of esophageal adenocarcinoma has increased rapidly in parallel with its premalignant condition, Barrett esophagus (BE). Unlike colonoscopy, endoscopic screening for BE is not currently recommended for all patients; however, surveillance endoscopy is advocated for patients with established BE. Novel imaging and sampling techniques have been developed and investigated for the purpose of improving the detection of Barrett esophagus, dysplasia, and neoplasia. Read More

Ann Otol Rhinol Laryngol 2018 Dec 21;127(12):926-930. Epub 2018 Sep 21.

3 Department of Speech and Hearing Sciences, Indiana University, Bloomington, IN, USA.

Introduction:: The aim of this study was to evaluate the current indications for and clinical factors influencing the use of transnasal esophagoscopy (TNE).

Methods:: An online survey was sent to American Broncho-Esophagological Association members, including questions on demographics, indications, and factors influencing the use of TNE.

Results:: Sixty of 251 members (24%) completed the survey. Read More

HNO 2018 Jul;66(7):534-542

Department of Otolaryngology Head and Neck Surgery, Hospital Universitario Puerta de Hierro Majadahonda, 1 Manuel de Falla Street, Majadahonda, 28222, Madrid, Spain.

Eosinophilic esophagitis (EoE) is a recently recognised pathologic entity whose prevalence has risen significantly since first being described in 1993. Defined as a chronic, local immune-mediated disease with predominant eosinophil infiltration, it is nowadays the leading cause of dysphagia and food bolus impaction in children and young adults. Genetic and environmental risk factors, and especially food antigens, trigger the disease and are in the focus of investigation as avoidance can cure three quarters of patients. Read More

J Otolaryngol Head Neck Surg 2018 May 15;47(1):35. Epub 2018 May 15.

Center for Voice and Swallowing, Department of Otolaryngology - Head & Neck Surgery, University of California Davis, Sacramento, CA, USA.

Background: Cricopharyngeus muscle dysfunction (CPMD) is a common cause of dysphagia. We employ a progressive series of three double-balloon dilations separated by 4-6 weeks between procedures as a primary treatment option. The purpose of this study was to evaluate subjective, functional and objective improvement in swallowing after three serial dilations for CPMD. Read More

Clin Otolaryngol 2018 Apr 10. Epub 2018 Apr 10.

Department of Gastroenterology, Royal Cornwall Hospital, Truro, UK.

Objectives: Dysphagia is a presenting symptom of both pharyngeal and oesophageal cancers. The referral pathway choice is determined by whether it is thought to be oropharyngeal or oesophageal, and this is in turn influenced by whether dysphagia is perceived to be above or below the suprasternal notch. We studied the concordance between the presence of pharynx-localised dysphagia (PLD) and the location of the underlying disease processes. Read More

J Otolaryngol Head Neck Surg 2018 Apr 3;47(1):23. Epub 2018 Apr 3.

Department of Otolaryngology-Head and Neck Surgery, University of Toronto, St-Michael's Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada.

Background: The advent of chip tip technology combined with advanced endoscopy has revolutionized the field of laryngology in the past decade. Procedures such as transnasal esophagoscopy, site-specific steroid injections, injection laryngoplasty and laryngeal laser treatment can now be performed in the office setting under local anaesthesia. Although In-Office Laryngeal Procedures (IOLPs) have become standard-of-care in many American and several Canadian centers, there are no guidelines regulating the practice of these procedures. Read More

Laryngoscope 2018 10 8;128(10):2261-2267. Epub 2018 Feb 8.

Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, U.S.A.

Objective: To review experience, safety, and cost of office-based esophageal dilation in patients with history of head and neck cancer (HNCA).

Methods: The medical records of patients undergoing esophageal dilation in the office were retrospectively reviewed between August 2015 and May 2017. Patients were given nasal topical anesthesia. Read More

Ear Nose Throat J 2017 Dec;96(12):E44

Department of Otolaryngology-Head and Neck Surgery, Medical College of Georgia at Augusta University, Augusta, GA, USA.

Logoped Phoniatr Vocol 2017 Nov 9:1-6. Epub 2017 Nov 9.

a Department of Otorhinolaryngology - Head and Neck Surgery , University of Helsinki and Helsinki University Hospital , Helsinki , Finland.

Globus may be a persistent symptom impairing patients' quality of life. Diagnostics and treatment are controversial but some globus patients may benefit from reassurance and attention. We investigated how globus symptoms change during a short-term follow-up without any treatment after an examination by an ear, nose and throat (ENT) physician and further diagnostic procedures. Read More

Gastrointest Endosc Clin N Am 2017 Jul 4;27(3):379-396. Epub 2017 Apr 4.

MRC Cancer Unit, Hutchinson/MRC Research Centre, University of Cambridge, Box 197, Cambridge Biomedical Campus, Cambridge CB2 0XZ, UK.

Barrett's esophagus (BE) predisposes patients to esophageal adenocarcinoma. 3 to 6% of individuals with gastro-esophageal reflux disease are estimated to have BE but only 20 to 25% of BE patients are currently diagnosed. The current gold standard for diagnosis of BE is per-oral upper GI endoscopy. Read More

J Pediatr Gastroenterol Nutr 2018 01;66(1):33-36

Department of Pediatrics.

Monitoring therapy in esophageal inflammatory disorders such as eosinophilic esophagitis and reflux esophagitis often requires frequent endoscopic evaluation. We recently reported the effective use of unsedated in-office transnasal esophagoscopy that significantly decreased costs and anesthetic exposure associated with pediatric esophagoscopy in eosinophilic esophagitis. Here we report a series of pediatric patients with esophagitis with gastrostomy tubes who underwent unsedated transgastrostomy esophagoscopy (TGE) in an office setting. Read More

Head Neck 2017 09 12;39(9):1910-1919. Epub 2017 May 12.

Department of Otorhinolaryngology and Head and Neck Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.

Background: Diagnostic and therapeutic office-based procedures under topical anesthesia are emerging in the daily practice of laryngologists and head and neck surgeons. Since the introduction of the transnasal esophagoscope, office-based procedures for the esophagus are increasingly performed.

Methods: We conducted a systematic review of literature on office-based procedures under topical anesthesia for the esophagus. Read More

Endosc Int Open 2017 May;5(5):E340-E344

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.

 Unsedated transnasal esophagoscopy (TNE) may offer a less expensive, mobile alternative to sedated esophagogastroduodenoscopy (EGD) for evaluations of reflux related complications. Comparisons of imaging quality by these methods are lacking.  Two reviewers evaluated videos of TNE and EGD procedures, performed during a community randomized study comparing endoscopic techniques. Read More

J Laryngol Otol 2017 Jul 20;131(7):650-654. Epub 2017 Apr 20.

Department of Otolaryngology - Head and Neck Surgery,Norfolk and Norwich University Hospital,Norwich,UK.

Objective: To assess the feasibility and outcomes of flexible carbon dioxide laser surgery in a clinic-based setting.

Methods: A prospective study was conducted in a tertiary centre. Clinical indications, clinical outcomes and patient satisfaction were assessed in patients treated with flexible carbon dioxide laser surgery via transnasal endoscopy and followed up over a period of up to nine months. Read More

Surg Innov 2017 Aug 6;24(4):353-357. Epub 2017 Apr 6.

1 University Hospitals Case Medical Center, Cleveland, OH, USA.

Background: With recent advancements in endoscopy, self-expandable metal stents (SEMS) have been used to treat gastrointestinal leaks, perforations, and strictures. Stent migration frequently complicates management and often requires additional treatments to reach resolution. Our study aimed to determine predictive factors for stent migration. Read More

Clin Otolaryngol 2017 Dec 18;42(6):1311-1318. Epub 2017 Apr 18.

Department of Otolaryngology-Head and Neck Surgery, Norfolk and Norwich University Hospital, Norwich, UK.

Objective: To explore the rationale for investigating patients presenting with globus symptoms. In this regard, we also assess the efficacy and safety of transnasal flexible laryngo-oesophagoscopy (TNFLO).

Methods: A prospective study in a head and neck cancer centre of patients with persistent globus symptoms with normal flexible nasoendoscopy/indirect mirror laryngoscopy and failure of first-line medical treatment. Read More

HNO 2017 Aug;65(Suppl 2):116-121

Refluxcenter Darmstadt, Darmstadt, Germany.

Classic gastroenterological diagnostic tools have proven to be insufficient in identifying the causal relationship between extra-esophageal symptoms and presumed pathological reflux activity. Some new methodological approaches, such as functional endoscopy (video panendoscopy, VPE), are considered to be helpful. However, there are currently no data objectively verifying the success of this method. Read More

Curr Gastroenterol Rep 2017 Mar;19(3)

Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Ave., S.W., Rochester, MN, 55905, USA.

Purpose Of Review: The costs to society and accuracy of screening for esophageal cancer and other esophageal diseases with standard endoscopy are formidable. As a result, the applicability of endoscopy as a general screening tool has been challenged.

Recent Findings: To maintain accuracy but reduce the price of endoscopy on society, multiple adjunct or replacement technologies are being developed that are less expensive and more easily applied. Read More

HNO 2017 Aug;65(8):657-662

Refluxzentrum Darmstadt, Darmstadt, Deutschland.

Classic gastroenterological diagnostic tools are proving increasingly insufficient for analyzing the complex causal relationship between extra-esophageal symptoms and presumed pathological reflux activity. Some new methodological approaches, such as functional endoscopy (videopanendoscopy, VPE), are considered to be helpful. However, there are currently no data objectively verifying the usefulness of this method. Read More

Laryngoscope 2016 12 17;126(12):2667-2671. Epub 2016 Aug 17.

Voice and Swallowing Institute, Department of Otolaryngology-Head and Neck Surgery, Columbia University Medical Center, New York, New York, U.S.A.

Objectives/hypothesis: To evaluate clinical indications and endoscopic findings for patients undergoing transnasal esophagoscopy (TNE).

Study Design: Prospective, multi-institutional, observational cohort study at four tertiary centers.

Methods: Demographics, reflux finding score, reflux symptom index, Eating Assessment Tool (EAT-10) scores, clinical indications, and endoscopic findings were compared among patients whose TNE findings resulted in a changes in management (FCIM), defined as a referral, new medication, or surgery recommendation. Read More

Clin Exp Otorhinolaryngol 2016 Dec 18;9(4):366-369. Epub 2016 Jun 18.

Department of Otorhinolaryngology, Head and Neck Surgery, Gulhane Military Medical Academy, Ankara, Turkey.

Objectives: Transnasal esophagoscopy (TNE) is a relatively new diagnostic procedure in the evaluation of patients with globus sensation and dysphagia. Enabling doctors to examine all of the upper aerodigestive system without the need for sedation, this technique is becoming more popular among otolaryngology specialists. The aim of this study is to evaluate the practicability of TNE and tolerability of patients to the test. Read More

Liver Int 2016 11 24;36(11):1639-1648. Epub 2016 May 24.

NIHR Nottingham Digestive Diseases Biomedical Research Unit, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK.

Background & Aims: Screening for oesophageal varices (OV) using conventional oesophagogastroduodenoscopy (C-OGD) is invasive and requires costly monitoring, recovery, and decontamination facilities. We aimed to evaluate the technical feasibility, acceptability and accuracy of a novel, portable and disposable office-based transnasal endoscope (EG Scan ) compared to C-OGD as the reference standard.

Methods: This was a prospective cohort study. Read More

Otolaryngol Head Neck Surg 2016 08 5;155(2):360-3. Epub 2016 Apr 5.

Department of Otolaryngology-Head and Neck Surgery, University of Michigan Health System, Ann Arbor, Michigan, USA

Oral Oncol 2016 Apr 1;55:55-60. Epub 2016 Feb 1.

Department of Otolaryngology, National Taiwan University Hospital and National Taiwan University, College of Medicine, Taipei, Taiwan; Graduate Institute of Pathology, National Taiwan University, College of Medicine, Taipei, Taiwan. Electronic address:

Objectives: Esophageal squamous cell carcinoma (ESCC) is common in hypopharyngeal squamous cell carcinoma (HSCC) patients. This prospective study is to reveal the prevalence of simultaneous ESCC in newly diagnosed HSCC patients by unsedated transnasal esophagogastroduodenoscopy (EGD) and to analyze the clinical predictors for simultaneous esophageal lesions and their survival.

Materials And Methods: 248 patients with newly diagnosed HSCC and without previous head and neck cancer between 2007 and 2014 were prospectively evaluated for HSCC and simultaneous esophageal lesions by unsedated transnasal EGD. Read More

Endoscopy 2016 Feb 28;48(2):105-6. Epub 2016 Jan 28.

Division of Gastroenterology, Case Western Reserve University, Cleveland, Ohio, United States.

Neurogastroenterol Motil 2016 05 6;28(5):680-6. Epub 2016 Jan 6.

Department of Otorhinolaryngology - Head and Neck Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Background: The etiology of globus is poorly understood. It is controversial, whether gastroesophageal reflux disease (GERD) has a role in globus. To investigate the possible esophageal background of this symptom, we performed transnasal esophagoscopy (TNE), high-resolution manometry (HRM), and 24-h multichannel intraluminal impedance (MII) and pH monitoring on globus patients. Read More

Ann R Coll Surg Engl 2016 Jan;98(1):49-52

Aneurin Bevan University Health Board , UK.

Introduction Transnasal oesophagoscopy is a relatively new method of examining the upper aerodigestive tract via the nasal passage as an outpatient procedure without the need for sedation. It has been shown to be a well tolerated, safe and accurate technique, that can therefore be used in the investigation of patients thought to have globus pharyngeus and other non sinister causes of dysphagia. Methods A total of 150 consecutive patients undergoing transnasal oesophagoscopy were analysed retrospectively. Read More

Endoscopy 2016 Feb 4;48(2):110-6. Epub 2015 Nov 4.

MRC Cancer Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, United Kingdom.

Background And Study Aims: The transnasal endosheath endoscope is a new disposable technology with potential applicability to the primary care setting. The aim of this study was to evaluate the efficacy of transnasal endosheath endoscopy (TEE) for the detection of Barrett's esophagus, by comparing the diagnostic accuracy of TEE with that of standard endoscopy.

Patients And Methods: This was a prospective, randomized, crossover study performed in a single tertiary referral center. Read More

Acta Otorrinolaringol Esp 2016 May-Jun;67(3):167-78. Epub 2015 Oct 9.

Servicio de Otorrinolaringología, Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda (Madrid), España.

Eosinophilic esophagitis (EE) is a recently recognised pathologic entity whose prevalence has risen significantly since it was first described. Its diagnosis represents a challenge for different medical specialties, among which ENT specialists play an important role. Clinical suspicion in a patient with recurrent food impaction or a child with eating disorders and history of hypersensitivity constitutes the first warning sign of a possible EE. Read More

Head Neck 2016 04 2;38 Suppl 1:E1137-43. Epub 2015 Sep 2.

Department of Otolaryngology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.

Background: The purposes of this study were to identify an index of symptoms and signs of swallowing disorders that indicate the occurrence of local recurrence or second primary malignancy and to evaluate the application of transnasal esophagoscopy in patients treated for head and neck squamous cell carcinoma (HNSCC).

Methods: Patients treated for HNSCC with swallowing disorders who received transnasal esophagoscopy examinations between January 2010 and June 2014 were included in this study. Local recurrence and second primary malignancy were pathologically diagnosed. Read More

Clin Exp Otorhinolaryngol 2015 Sep 13;8(3):261-7. Epub 2015 Aug 13.

Department of Otorhinolaryngology, Gyeongsang National University School of Medicine, Jinju, Korea. ; Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea.

Objectives: Fish bone impaction in the upper gastrointestinal tract is a common reason for patients to seek emergent care. The aim of this study was to find a clinical characteristics of patients with fish bone impaction in the upper gastrointestinal tract.

Methods: The study was conducted on 286 fish bone ingestion patients who complained of dysphagia and irritation after eating fish. Read More

Gastrointest Endosc 2016 Feb 2;83(2):299-306.e1. Epub 2015 Jul 2.

Aerodigestive Program, Children's Hospital Colorado, Aurora, Colorado, USA; Department of Otolaryngology, Children's Hospital Colorado, Department of Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado, USA.

Background And Aims: Unsedated transnasal endoscopy (TNE) is safer and less costly than sedated EGD. The aim of this study was to evaluate the performance of TNE with biopsies in monitoring the esophageal mucosa of pediatric patients with eosinophilic esophagitis.

Methods: Patients between 8 and 17 years of age with eosinophilic esophagitis and their parents were enrolled. Read More

Ann Otol Rhinol Laryngol 2015 Dec 19;124(12):940-6. Epub 2015 Jun 19.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland, USA

Objectives: To compare patterns of laryngopharyngeal reflux (LPR) diagnosis and management over time by American Broncho-Esophagological Association (ABEA) members.

Methods: American Broncho-Esophagological Association members completed an online questionnaire focused on LPR evaluation and management in 2012; responses were compared to a 2002 survey.

Results: Four hundred twenty-six members were emailed, of whom 63 (14. Read More

Head Neck 2016 Mar 7;38(3):E61-3. Epub 2015 Sep 7.

Department of Otolaryngology-Head and Neck Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana.

Background: There is debate about the optimal voice restoration method and technique for patients who have undergone total laryngopharyngectomy, esophagectomy, and gastric pull-up. The purpose of this study was to report a series of patients who underwent awake, secondary tracheoesophageal puncture (TEP) after this procedure.

Methods: A retrospective chart review was performed at a tertiary referral center. Read More

Laryngoscope 2015 Nov 11;125(11):2472-5. Epub 2015 May 11.

College of Nursing, Gyeongsang National University, Jinju, Republic of Korea.

Objective: To investigate the methods of diagnosis of fish bone foreign body in the esophagus and suggest a diagnostic protocol.

Study Design: Prospective cohort study.

Methods: A prospective study was performed on 286 patients with a history of fish bone foreign body impaction. Read More

Otolaryngol Head Neck Surg 2015 Aug 16;153(2):189-92. Epub 2015 Apr 16.

Department of Otorhinolaryngology-Head and Neck Surgery, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan Medical School, Fu-Jen Catholic University, Taipei, Taiwan

Objectives: (1) To analyze the outcomes of patients with esophageal foreign body managed by transnasal esophagoscopy. (2) To review the value of lateral neck X-ray.

Study Design: Case series with chart review. Read More

Clin Otolaryngol 2015 Apr;40(2):167

Otolaryngology-Head and Neck Surgery, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, UK.

Otolaryngol Head Neck Surg 2015 May 27;152(5):874-80. Epub 2015 Jan 27.

Department of Otolaryngology, Cathay General Hospital, Taipei, Taiwan, Republic of China.

Objective: To compare the difference between white light (WL) and narrow-band imaging (NBI) endoscopy in evaluating patients who had reflux laryngitis and esophagitis.

Study Design: Retrospective review of medical records and endoscopic images.

Setting: Outpatient clinic. Read More

Surgeon 2016 Feb 13;14(1):22-5. Epub 2015 Jan 13.

Lister Hospital, Department of ORL, Stevenage, UK.

Introduction: A large number of patients present in Otolaryngology clinics with vague upper gastro intestinal symptoms, some potentially originating from the oesophagus. In the United Kingdom there is no consensus for investigation protocols. The concern is that diagnosis of early oesophageal malignancy can be delayed with detrimental effects to the prognosis of the patient. Read More

Med J Malaysia 2014 Aug;69(4):162-5

Health Technology Assessment Section (MaHTAS), Medical Development Division, Ministry of Health Malaysia.

A Health Technology Assessment (HTA) was conducted in 2011 to evaluate whether transnasal oesophagoscopy (TNE) should be made available at otorhinolaryngology (ORL) clinics in the Ministry of Health facilities. The safety, efficacy or effectiveness and economic implication of using transnasal oesophagoscopy (TNE) were reviewed. This review provides a summary of the HTA and an updated literature review as well as how this technology might potentially affect services in the Ministry of Health. Read More

Curr Opin Otolaryngol Head Neck Surg 2015 Apr;23(2):171-5

NYU Voice Center, Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, New York, New York, USA.

Purpose Of Review: The role of transnasal esophagoscopy (TNE) in the evaluation and management of the head and neck cancer patient is evolving. This study reviews the most recent advances in the use of this technology in the head and neck patient population.

Recent Findings: It appears that in-office, unsedated TNE is a useful alternative to conventional endoscopy in the evaluation and management of the head and neck patient. Read More

Ann Otol Rhinol Laryngol 2015 Mar 15;124(3):221-6. Epub 2014 Sep 15.

Department of Head and Neck Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA

Objective: This study aimed to describe management of esophageal stenosis after chemoradiation therapy for head and neck squamous cell carcinoma (HNSCC), with particular emphasis on techniques and outcomes with the use of the transnasal esophagoscope (TNE) in the office as well as operating room settings.

Methods: Retrospective analysis of all patients with esophageal stenosis following head and neck cancer radiation, with or without chemotherapy, and managed with TNE-assisted esophageal dilation over a 5-year period. Preoperative and postoperative swallowing function were assessed objectively with the Functional Outcome Swallowing Scale (FOSS; ranging from score 0, a normal diet, to score 5, complete dependence on nonoral nutrition). Read More

Gastrointest Endosc 2014 Nov 25;80(5):774-82. Epub 2014 Jun 25.

Department of Gastroenterology, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA; Digestive Health Institute, University Hospitals Case Medical Center, Cleveland, Ohio, USA; Department of Gastroenterology, Case Western Reserve University, Cleveland, Ohio, USA.

Background: EGD screening for Barrett's esophagus (BE) is costly, with insufficient evidence to support its effectiveness.

Objective: To compare acceptance and tolerability of 2 novel, office-based, endoscopic screening techniques done on nonsedated patients.

Design: Randomized block study design with allocation concealment. Read More

Clin Exp Otorhinolaryngol 2014 Jun 21;7(2):123-5. Epub 2014 May 21.

Department of Otolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon, Korea.

Objectives: The purpose of study was to report the current role of transnasal esophagoscopy (TNE) in Korea.

Methods: One hundred thirty-seven patients who underwent TNE at Soonchunhyang University Bucheon Hospital (n=69) and Korea University Anam Hospital (n=68) from July 2007 to February 2009 were prospectively analyzed. Laryngopharyngeal reflux disease (LPRD) patients without any response to proton-pump inhibitor (n=102), and patients with complaints that require esophagoscopy as part of their evaluation (n=35) were included in this study; investigation of metachronous lesions or routine follow-up screening of head and neck cancer patients, n=17; dysphagia, n=9; blood tinged saliva, n=4; to determine the cause of vocal fold paralysis as screening tool, n=4; suspicious esophageal foreign body, n=1. Read More

World J Gastrointest Endosc 2014 Apr;6(4):128-36

María R Aedo, Miguel Á Zavala-González, Arturo Meixueiro-Daza, José María Remes-Troche, Laboratorio de Fisiología Digestiva y Motilidad Gastrointestinal, Instituto de Investigaciones Médico-Biológicas, Universidad Veracruzana, Veracruz 94299, México.

Aim: To assess feasibility of unsedated esophagoscopy using a small-caliber disposable transnasal esophagoscopy and to compare its accuracy with standard endoscopy.

Methods: We prospectively included subjects who were referred for upper endoscopy. All subjects underwent transnasal endoscopy with E. Read More