106,729 results match your criteria Esophagogastroduodenoscopy


The endoscopists' biopsy rate as a quality indicator for outpatient gastroscopy: a multicenter cohort study with validation.

Gastrointest Endosc 2019 Jan 16. Epub 2019 Jan 16.

Department of Gastroenterological Oncology, the Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland; Department of Gastroenterology, Hepatology and Clinical Oncology, Medical Centre for Postgraduate Education, Warsaw, Poland; Department of Cancer Prevention, the Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland (Unit A); Department of Health Management and Health Economics, University of Oslo, Oslo, Norway.

Background And Aims: The gastric premalignant conditions (GPCs) diagnosis rely on endoscopy with mucosal sampling. We hypothesized that the endoscopists' biopsy rate (EBR) might constitute a quality indicator for esophagogastroduodenoscopy (EGD) and we have analyzed its association with GPC detection and the rate of missed gastric cancers (GCs).

Methods: We analyzed EGD databases from 2 high-volume outpatient units. Read More

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http://dx.doi.org/10.1016/j.gie.2019.01.008DOI Listing
January 2019
1 Read

Glomus tumor of the stomach treated by laparoscopic distal gastrectomy: A case report.

Oncol Lett 2019 Jan 25;17(1):514-517. Epub 2018 Oct 25.

Department of Surgery, Kochi Medical School, Nankoku, Kochi 783-8505, Japan.

Glomus tumor of the stomach is a rare submucosal mesenchymal tumor. The present study reports a patient with gastric glomus tumor treated by laparoscopic distal gastrectomy. A 39-year-old male was referred to Kochi Medical School Hospital for examination of a gastric submucosal tumor (SMT) initially diagnosed following a medical check-up. Read More

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http://dx.doi.org/10.3892/ol.2018.9621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313179PMC
January 2019

Esophageal carcinosarcoma that disappeared pathologically by palliative radiotherapy alone.

Clin J Gastroenterol 2019 Jan 16. Epub 2019 Jan 16.

Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, 565-0871, Osaka, Japan.

Only a few cases of esophageal granulocyte-colony-stimulating-factor (G-CSF)-producing esophageal carcinosarcoma are reported, and patients with G-CSF-producing tumors are typically considered to have poor prognosis. An 89-year-old man was examined for low-grade fever and dysphagia. Chest computed tomography revealed a huge 80-mm tumor on the thoracic esophagus without direct invasion to surrounding organs. Read More

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http://dx.doi.org/10.1007/s12328-019-00933-7DOI Listing
January 2019

Transnasal Esophagoscopy-Our Experience.

Int Arch Otorhinolaryngol 2019 Jan 11;23(1):7-11. Epub 2018 Oct 11.

Department of ENT, Lancaster Royal Infirmary, Lancaster, United Kingdom of Great Britain and Northern Ireland.

 Transnasal esophagoscopy (TNE) is a widely used tool both in the diagnosis and treatment of patients presenting complaints within the head and the neck. This is because this investigative adjunct examination provides the advantage of visualizing above the level of the cricopharyngeus muscle when compared to the more widely used esophagogastroduodenoscopy (EGD).  We have assessed if the implementation of TNE within a district general hospital (DGH) was feasible, and investigated if the resources of our patients could be better directed away from other investigations such as barium swallow and EGD in favor of this novel technique. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1661359
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http://dx.doi.org/10.1055/s-0038-1661359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331291PMC
January 2019
1 Read

Assessment of Esophageal Motor Disorders Using High-resolution Manometry in Esophageal Dysphagia With Normal Endoscopy.

J Neurogastroenterol Motil 2019 Jan;25(1):61-67

Department of Gastroenterology, the First Hospital of Jilin University, China.

Background/aims: The distribution and esophageal motor characteristics of Chinese patients with esophageal dysphagia who exhibit no structural abnormalities on esophagogastroduodenoscopy remain unclear. Our aim is to assess the esophageal motor patterns using high-resolution manometry (HRM) and classify them according to the Chicago classification version 3.0 (CC v3. Read More

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http://www.jnmjournal.org/journal/view.html?doi=10.5056/jnm1
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http://dx.doi.org/10.5056/jnm18042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326201PMC
January 2019
1 Read

Buried coin in the gastric mucosa.

BMJ Case Rep 2019 Jan 14;12(1). Epub 2019 Jan 14.

County Hospital Hereford, Hereford, United Kingdom.

A 29-year-old man presented to the Accident and Emergency department with abdominal cramping following ingestion of a 50 p coin 2½ weeks prior to presentation. He had not observed it pass in his stools. An abdominal radiograph confirmed the presence of the 50 p coin in his stomach. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22762
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http://dx.doi.org/10.1136/bcr-2018-227622DOI Listing
January 2019
2 Reads

Impact of preoperative wireless pH monitoring in the evaluation of esophageal conditions prior to bariatric surgery in a severely obese patient population.

Surg Obes Relat Dis 2018 Nov 23. Epub 2018 Nov 23.

Department of General Surgery and the Bariatric and Metabolic Institute, Cleveland Clinic Florida, Weston, Florida. Electronic address:

Background: Sleeve gastrectomy (SG) is currently the most commonly performed bariatric procedure in the United States; however, it can be associated with development of de novo gastroesophageal reflux (GERD) or worsening of existing GERD. Preoperative esophagogastroduodenoscopy (EGD) and findings of esophagitis are commonly used as screening tool, but the alternative use of preoperative objective measurement of acid reflux has not been studied.

Objective: The aim of this study was to evaluate if preoperative objective measurement of acid reflux by using wireless pH monitoring (WPHM) could have an impact on surgical planning and outcomes. Read More

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http://dx.doi.org/10.1016/j.soard.2018.11.014DOI Listing
November 2018
1 Read

Esophageal Basaloid Squamous Carcinoma Treated by Endoscopic Resection and Radiation.

Korean J Gastroenterol 2018 Nov;72(5):258-261

Department of Pathology, Yeungnam University College of Medicine, Daegu, Korea.

Esophageal basaloid squamous carcinoma (BSC) is a rare, aggressive variant of squamous cell carcinoma. BSC is usually diagnosed in advanced stage and its prognosis is relatively poor. A 59-year-old male with subepithelial lesion of the esophagus that was incidentally discovered during health promotion examination was referred to our hospital. Read More

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http://dx.doi.org/10.4166/kjg.2018.72.5.258DOI Listing
November 2018
1 Read

A neonate with pneumoperitoneum and cyanosis of lower limbs skin during esophagogastroduodenoscopy.

Dig Liver Dis 2019 Jan 3. Epub 2019 Jan 3.

Department of Internal Medicine, Toyama Prefectural Central Hospital, Toyama, Japan.

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http://dx.doi.org/10.1016/j.dld.2018.12.015DOI Listing
January 2019
1 Read

Etiologies and clinical characteristics of non-obstructive dysphagia in a Taiwanese population: A prospective study based on high-resolution impedance manometry.

J Formos Med Assoc 2019 Jan 8. Epub 2019 Jan 8.

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. Electronic address:

Background: Esophageal motility disorders are the major cause of non-obstructive dysphagia (NOD), but may be underdiagnosed. In this high-resolution impedance manometry (HRIM)-based study, we aimed to clarify the etiologies and clinical characteristics of patients presenting with NOD in a Taiwanese population.

Methods: From October 2014 to July 2017, consecutive patients with the chief complaint of dysphagia were prospectively enrolled in the study at a tertiary medical center. Read More

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http://dx.doi.org/10.1016/j.jfma.2018.12.019DOI Listing
January 2019
1 Read

Orbital Hematoma: A New Complication of Esophagogastroduodenoscopy.

Am J Gastroenterol 2019 Jan;114(1):181-182

Department of Gastroenterology, Lokmanya Tilak Municipal Medical College and General Hospital, Sion, Mumbai, India.

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http://dx.doi.org/10.14309/ajg.0000000000000047DOI Listing
January 2019

Black Esophagus: A Rare Case of Acute Esophageal Necrosis Induced by Diabetic Ketoacidosis in a Young Adult Female.

Case Rep Gastrointest Med 2018 29;2018:7363406. Epub 2018 Nov 29.

Division of Academic Affairs and Research, Orlando Regional Healthcare, Orlando, FL, USA.

Background: Acute esophageal necrosis is an uncommon clinical disorder diagnosed on endoscopy as a black esophagus. It has a multifactorial etiology that probably represents a combination of poor nutritional status, gastric outlet obstruction, and ischemia secondary to hypoperfusion of the distal esophagus. It typically occurs in older males with comorbidities. Read More

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https://www.hindawi.com/journals/crigm/2018/7363406/
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http://dx.doi.org/10.1155/2018/7363406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304633PMC
November 2018
5 Reads

Endoscopic evaluation of immunotherapy-induced gastrointestinal toxicity.

World J Gastrointest Endosc 2018 Dec;10(12):392-399

Digestive Disease Department, General University Hospital of Valencia, Valencia 46014, Spain.

Immunotherapy is any treatment aimed at boosting or enhancing the immune system. It includes a wide range of options, from vaccines to treatment for conditions such as allergy and cancer. In the case of cancer, unlike other available treatments, immunotherapy is not aimed at destroying the tumor cells but at stimulating the patient's immune system so that it attacks the tumor. Read More

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https://www.wjgnet.com/1948-5190/full/v10/i12/392.htm
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http://dx.doi.org/10.4253/wjge.v10.i12.392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323501PMC
December 2018
2 Reads

Incidentally Detected Amyloid Light-Chain Amyloidosis Caused by Monoclonal Gammopathy of Undetermined Significance: Possible Time-Dependent Change in Colonic Findings.

Case Rep Gastroenterol 2018 Sep-Dec;12(3):737-746. Epub 2018 Dec 6.

Division of Gastroenterology and Hepatology, Third Department of Internal Medicine, Kansai Medical University, Hirakata, Hirakata, Japan.

Amyloid light-chain (AL) amyloidosis is associated with plasma cell disorder and monoclonal light chains. This type of amyloidosis is the prominent type involving the gastrointestinal tract. Monoclonal gammopathy of undetermined significance (MGUS) is the most common plasma cell disorder and a known precursor of more serious diseases. Read More

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http://dx.doi.org/10.1159/000494919DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323391PMC
December 2018
1 Read

Successful Endoscopic Closure Using Polyglycolic Acid Sheets with Fibrin Glue for Nonhealing Duodenal Ulcer with Perforation after Proton Beam Therapy of Liver Tumor.

Case Rep Gastroenterol 2018 Sep-Dec;12(3):679-685. Epub 2018 Nov 28.

Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.

We describe the first case of a nonhealing duodenal ulcer with perforation after proton beam therapy (PBT) of a liver tumor that was successfully treated endoscopically using polyglycolic acid (PGA) sheets with fibrin glue. A 69-year-old man received PBT for a liver tumor. Esophagogastroduodenoscopy (EGD) 3 months after PBT revealed a duodenal ulcer. Read More

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https://www.karger.com/Article/FullText/494918
Publisher Site
http://dx.doi.org/10.1159/000494918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323404PMC
November 2018
2 Reads

Overview of Deep Learning in Gastrointestinal Endoscopy.

Gut Liver 2019 Jan 11. Epub 2019 Jan 11.

Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.

Artificial intelligence is likely to perform several roles currently performed by humans, and the adoption of artificial intelligence-based medicine in gastroenterology practice is expected in the near future. Medical image-based diagnoses, such as pathology, radiology, and endoscopy, are expected to be the first in the medical field to be affected by artificial intelligence. A convolutional neural network, a kind of deep-learning method with multilayer perceptrons designed to use minimal preprocessing, was recently reported as being highly beneficial in the field of endoscopy, including esophagogastroduodenoscopy, colonoscopy, and capsule endoscopy. Read More

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http://www.gutnliver.org/journal/view.html?doi=10.5009/gnl18
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http://dx.doi.org/10.5009/gnl18384DOI Listing
January 2019
4 Reads

Genetic variability of the ABCC2 gene and clinical outcomes in pancreatic cancer patients.

Carcinogenesis 2019 Jan 9. Epub 2019 Jan 9.

Department of Biology, University of Pisa, Pisa, Italy.

Pancreatic ductal adenocarcinoma (PDAC) has an extremely poor prognosis, caused by various factors, such as the aggressiveness of the disease, the limited therapeutic options and the lack of early detection and risk markers. The ATP binding cassette subfamily C member 2 (ABCC2) protein plays a critical role in response to various drugs and is differentially expressed in gemcitabine sensitive and resistant cells. Moreover, Single Nucleotide Polymorphisms (SNPs) in the gene have been associated with differential outcomes and prognosis in several tumour types. Read More

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https://academic.oup.com/carcin/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/carcin/bgz006DOI Listing
January 2019
2 Reads

Long-term follow-up of gastric squamous metaplasia.

Dig Endosc 2019 Jan 9. Epub 2019 Jan 9.

Second Department of Internal Medicine, Osaka Medical College, Osaka, Japan.

A man in his eighties underwent surveillance esophagogastroduodenoscopy after curative endoscopic submucosal dissection for early gastric cancer in the lesser curvature of gastric angle. Endoscopy showed atrophic gastritis (the serum antibody of H. pylori was positive) and an 8 mm, whitish slightly depressed lesion at the posterior wall of the gastric antrum (Fig. Read More

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http://dx.doi.org/10.1111/den.13338DOI Listing
January 2019

Virtual reality simulation in endoscopy training: Current evidence and future directions.

World J Gastroenterol 2018 Dec;24(48):5439-5445

Division of Gastroenterology, St. Michael's Hospital, University of Toronto, Toronto M5B 1W8, Canada.

Virtual reality simulation is becoming the standard when beginning endoscopic training. It offers various benefits including learning in a low-stakes environment, improvement of patient safety and optimization of valuable endoscopy time. This is a review of the evidence surrounding virtual reality simulation and its efficacy in teaching endoscopic techniques. Read More

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https://www.wjgnet.com/1007-9327/full/v24/i48/5439.htm
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http://dx.doi.org/10.3748/wjg.v24.i48.5439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319131PMC
December 2018
3 Reads

Effect of cap-assisted esophagogastroduodenoscopy on examination of the major duodenal papilla: a noninferior, randomized controlled trial.

Endoscopy 2019 Jan 8. Epub 2019 Jan 8.

State Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi'an, Shaanxi, China.

Background:  Cap-assisted esophagogastroduodenoscopy (CA-EGD) using a transparent cap fitted to the tip of the scope has emerged as an alternative method for examination of the major duodenal papilla (MDP). However, it remains unclear whether CA-EGD is noninferior to standard duodenoscopy for MDP examination. The aim of this study was to compare the efficacies of the two methods for complete examination of the MDP. Read More

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http://dx.doi.org/10.1055/a-0767-6529DOI Listing
January 2019
2 Reads

Duodenal variceal bleeding secondary to idiopathic portal hypertension treated with transjugular intra-hepatic porto-systemic shunt plus embolization: A case report.

World J Clin Cases 2018 Dec;6(16):1217-1222

Department of Gastroenterology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China.

Background: Duodenal varices are a lesser-known complication with non-cirrhotic portal hypertension. We report a circuitous route from missed diagnosis of duodenal varices to correction. An extremely rare case of duodenal variceal bleeding secondary to idiopathic portal hypertension (IPH) is expounded in this study, which was controlled by transjugular intra-hepatic porto-systemic shunt (TIPS) plus embolization. Read More

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http://dx.doi.org/10.12998/wjcc.v6.i16.1217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306627PMC
December 2018
1 Read

Contrast-Enhanced µCT for Visualizing and Evaluating Murine Intestinal Inflammation.

Theranostics 2018 7;8(22):6357-6366. Epub 2018 Dec 7.

Department of Medicine 1, Friedrich-Alexander-University Erlangen-Nuremberg, Hartmannstraße 14, 91052 Erlangen, Germany.

: To develop a simple and fast protocol for the assessment of acute and chronic experimental intestinal inflammation using contrast-enhanced µCT. : For the imaging studies, an acute 2% and 3% dextran sodium sulfate (n = 15, female, 8-12 weeks) and a chronic adoptive transfer colitis model (n = 10, female, 8-9 weeks) were established over 9 days or 6 weeks, respectively. Throughout the experiments, longitudinal measurement of murine intestinal wall thickness and time dependent perfusion was performed on a small animal µCT system (90 kV, 160 μA, FOV: 60 mm, scan time: 17 s, image size: 512x512, layer thickness: 118 µm) between 0. Read More

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http://www.thno.org/v08p6357.htm
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http://dx.doi.org/10.7150/thno.26013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299705PMC
December 2018
2 Reads

New Ovine Polymer-Reinforced Bioscaffold in Hiatal Hernia Repair.

JSLS 2018 Oct-Dec;22(4)

Department of Surgery, Oklahoma State University, Comanche County Memorial Hospital, Lawton, Oklahoma, USA.

Background And Objectives: Biologic and resorbable synthetic materials are used commonly for crural repair reinforcement during laparoscopic hiatal herniorrhaphy. Recently, an ovine polymer-reinforced bioscaffold (OPRBS) has been developed for reinforcement of abdominal wall and hiatal herniorrhaphies. This is the first reported series on use of OPRBS in hiatal hernia repairs. Read More

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305064/
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http://dx.doi.org/10.4293/JSLS.2018.00057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305064PMC
January 2019
6 Reads

Transoral Incisionless Fundoplication TIF 2.0 with "EsophyX Z®" Device for GERD: Seven Years after Endo Lumenal Fundoplication. World’s First Case Report.

Chirurgia (Bucur) 2018 Nov-Dec;113(6):849-856

Transoral Incisionless Fundoplication (TIF) with EsophyX device for a well selected GERD patient population has proven its efficacy, safety and durability. We present a case report of a male, 63 y old, with typical and atypical GERD symptoms started 15 years ago. The esophagogastroduodenoscopy (EGD) showed a Hiatal Hernia (HH) of 3 cm and an erosive esophagitis Los Angeles Grade B. Read More

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http://dx.doi.org/10.21614/chirurgia.113.6.849DOI Listing
December 2018
1 Read

Associated risk factors for psychological distress in patients with gastric epithelial neoplasm undergoing endoscopic submucosal dissection.

Medicine (Baltimore) 2018 Dec;97(52):e13912

Department of Internal Medicine.

This study aimed to evaluate the psychological distress and associated risk factors for distress among patients with gastric epithelial neoplasm undergoing endoscopic submucosal dissection (ESD).A total of 91 patients treated with ESD for gastric epithelial neoplasm between May 2015 and June 2016 were prospectively enrolled. Sociodemographic factors, psychological distress, anxiety, depression, stress, and associated risk factors for psychological distress were evaluated the day before ESD. Read More

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http://dx.doi.org/10.1097/MD.0000000000013912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314696PMC
December 2018

Endoscopic submucosal dissection of papillary adenocarcinoma of stomach; protocol for a systematic review and meta-analysis.

Medicine (Baltimore) 2018 Dec;97(52):e13905

Department of Internal Medicine.

Background: Endoscopic submucosal dissection (ESD) is a primary treatment for the early gastric cancer (EGC) who has a negligible risk of lymph node metastasis. Papillary adenocarcinoma (PAC) of stomach is a rare histologic variant of gastric cancer and categorized into EGC with differentiated-histology. However, aggressive features such as higher rate of lymphovascular invasion (LVI) or submucosal invasion have been reported, whereas comparable lymph node metastasis (LNM) rate to the lesions meeting the current ESD criteria also has been reported. Read More

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http://dx.doi.org/10.1097/MD.0000000000013905DOI Listing
December 2018
1 Read
5.723 Impact Factor

CT-quantified muscle and fat change in patients after surgery or endoscopic resection for early gastric cancer and its impact on long-term outcomes.

Medicine (Baltimore) 2018 Dec;97(52):e13878

Department of Radiology, Seoul St. Mary's Hospital.

The purpose of this study was to evaluate the impact of the body composition changes on patients' long-term outcomes after endoscopic resection or surgery for mucosal gastric cancer.This case-control study included 96 patients who underwent endoscopic resection or surgery after propensity score matching. Areas of fat and muscle measured on CT were compared between the 2 groups. Read More

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http://dx.doi.org/10.1097/MD.0000000000013878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314738PMC
December 2018

Comparison of a New-generation Fecal Immunochemical Test (FIT) With Guaiac Fecal Occult Blood Test (gFOBT) in Detecting Colorectal Neoplasia Among Colonoscopy-referral Patients.

Anticancer Res 2019 Jan;39(1):261-269

Molecular Oncology Research Center, School of Health Sciences, University of Minho, Braga, Portugal

Background/aim: The aim of the present study was to compare fecal immunochemical tests (FITs) for colorectal cancer (CRC) screening with the traditional guaiac-based FOB tests (gFOBT).

Materials And Methods: A cohort of 368 colonoscopy-referral patients were evaluated by i) the new-generation FIT: ColonView quick test (CV; Biohit Oyj, Finland) and ii) a conventional gFOBT HemoccultSENSA (HS; Beckman Coulter, USA). Three fecal samples were requested for both assays, and all subjects underwent diagnostic colonoscopy with biopsy confirmation. Read More

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http://ar.iiarjournals.org/lookup/doi/10.21873/anticanres.13
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http://dx.doi.org/10.21873/anticanres.13106DOI Listing
January 2019
4 Reads

A severe case of refractory esophageal stenosis induced by nivolumab and responding to tocilizumab therapy.

J Immunother Cancer 2018 Dec 27;6(1):156. Epub 2018 Dec 27.

Department of Medicine, Division of Immunology and Allergy, Lausanne University Hospital CHUV, rue du Bugnon 46, CH-1011, Lausanne, Switzerland.

Background: The prevalence of esophageal stenosis caused by immune checkpoint inhibitors in the context of induced immune mucositis and esophagitis is extremely rare.

Case Presentation: We report the case of a patient with stage IV pulmonary adenocarcinoma treated for 6 months with nivolumab who developed bilateral sterile conjunctivitis followed by oropharyngeal mucositis and esophagitis complicated by a severe esophageal stenosis. The laryngeal margin and hypopharyngeal mucosa appeared highly inflammatory with fibrinous deposits. Read More

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https://jitc.biomedcentral.com/articles/10.1186/s40425-018-0
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http://dx.doi.org/10.1186/s40425-018-0481-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307169PMC
December 2018
3 Reads

Endoscopic and clinicopathological features of intramucosal, histologically mixed-type, low-grade, well-differentiated gastric tubular adenocarcinoma with the potential for late-onset lymph node metastasis.

BMC Gastroenterol 2018 Dec 27;18(1):189. Epub 2018 Dec 27.

Department of Pathology, Niigata Cancer Center Hospital, 2-15-3 Kawagishi-cho, Chuo-ku, Niigata, 951-8566, Japan.

Background: Intramucosal, histologically mixed-type, low-grade (LG), well-differentiated gastric tubular adenocarcinomas (tub1s; LG-tub1s) have larger mean diameters and exhibit a higher frequency of the gastric mucin phenotype (G-phenotype) than pure LG-tub1s. In proportion to their increases in diameter, G-phenotype differentiated-type early gastric cancer (EGC) tumours reportedly grow to eventually contain (an) undifferentiated-type component(s) and LG-tub1s, which are included in differentiated-type EGCs, reportedly exhibit changes in their glandular architectural and cytological atypia grades from LG to high-grade (HG) and can grow to contain a moderately differentiated tubular adenocarcinoma (tub2) component and undifferentiated components. Because they generally show a higher frequency of malignancy relative to tumours with a higher atypia grade and lower differentiation degree, it is suggested that, among mixed-type LG-tub1s, G-phenotype LG-tub1s containing an HG-tub2 component (LG-tub1s > HG-tub2) with undifferentiated components might lead to late-onset metastasis to lymph nodes even after a successful endoscopic submucosal dissection (ESD). Read More

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https://bmcgastroenterol.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12876-018-0919-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307236PMC
December 2018
2 Reads

Gastric Metastasis Mimicking Linitis Plastica 20 Years after Primary Breast Cancer. A Case Report.

J Gastrointestin Liver Dis 2018 Dec;27(4):469-471

Department of Medical Oncology, Pôle de Santé Saint Jean, Cagnes-sur-Mer, France.

Breast cancer metastases to the gastrointestinal tract are rare, with a median time interval from the diagnosis of the primary tumor to metastasis up to 7 years. The stomach is the most frequent metastatic site and invasive lobular carcinoma is the type with the highest affinity to the digestive system. We report the case of an 84-year-old female patient, with a past medical history 20 years earlier of invasive lobular carcinoma of the breast, who presented for dyspepsia. Read More

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http://dx.doi.org/10.15403/jgld.2014.1121.274.gasDOI Listing
December 2018

Endoscopic submucosal dissection of early gastric cancer with mixed-type histology: Protocol for a systematic review and meta-analysis.

Medicine (Baltimore) 2018 Dec;97(51):e13838

Department of Internal Medicine.

Background: Endoscopic submucosal dissection (ESD) is a primary treatment for the early gastric cancer (EGC) who have a negligible risk of lymph node metastasis satisfying specific criteria. These criteria are histologically categorized by EGC with differentiated-type histology (EGC-DH) and undifferentiated-type histology (EGC-UH). However, gastric cancer is histologically heterogenous and there has been no specific criteria for EGC with mixed-type histology (EGC-MH). Read More

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http://dx.doi.org/10.1097/MD.0000000000013838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320129PMC
December 2018
5.723 Impact Factor

A case report of endoscopic therapy for radiation-induced hemorrhagic gastritis in patient with recurrent hepatocellular carcinoma.

Medicine (Baltimore) 2018 Dec;97(51):e13535

Department of Digestive Disease, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Soochow University.

Rationale: Radiation-induced hemorrhagic gastritis is an infrequent cause of upper gastrointestinal bleeding and difficult to manage. The current standard treatment has not been well established.

Patient Concerns: We described a 32-year-old male patient with hemorrhagic gastritis induced by external radiotherapy for hepatocellular carcinoma recurrence. Read More

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http://dx.doi.org/10.1097/MD.0000000000013535DOI Listing
December 2018
2 Reads

Renal cell carcinoma presenting as nonspecific gastrointestinal symptoms: a case report.

Int Med Case Rep J 2018 27;11:345-348. Epub 2018 Nov 27.

Willow Bank Surgery, NHS, Stoke-on-Trent, UK.

Background: Renal cell carcinoma (RCC) arises from the renal epithelium and accounts for more than 90% of kidney cancers. RCC has a diverse range of clinical manifestations. The classical triad of loin pain, hematuria and abdominal mass is only present in 4%-17% of cases. Read More

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http://dx.doi.org/10.2147/IMCRJ.S178816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267697PMC
November 2018

Narrow band imaging and white light endoscopy in the characterization of a polypectomy scar: A single-blind observational study.

World J Gastroenterol 2018 Dec;24(45):5179-5188

Gastroenterology Department, Hospital del Mar, Barcelona 08003, Spain.

Aim: To assess the incremental benefit of narrow band imaging (NBI) and white light endoscopy (WLE), randomizing the initial technique for the detection of residual neoplasia at the polypectomy scar after an endoscopic piecemeal mucosal resection (EPMR).

Methods: We conducted an observational study in an academic center to assess the incremental benefit of NBI and WLE randomly applied 1:1 (NBI-WLE or WLE-NBI) in the follow-up of a post-EPMR scar by the same endoscopist.

Results: A total of 112 EPMR scars were included. Read More

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http://www.wjgnet.com/1007-9327/full/v24/i45/5179.htm
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http://dx.doi.org/10.3748/wjg.v24.i45.5179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288651PMC
December 2018
3 Reads

Methodology to develop machine learning algorithms to improve performance in gastrointestinal endoscopy.

World J Gastroenterol 2018 Dec;24(45):5057-5062

Center for Digital Engineering Simula Metropolitan, Fornebu 1364, Norway.

Assisted diagnosis using artificial intelligence has been a holy grail in medical research for many years, and recent developments in computer hardware have enabled the narrower area of machine learning to equip clinicians with potentially useful tools for computer assisted diagnosis (CAD) systems. However, training and assessing a computer's ability to diagnose like a human are complex tasks, and successful outcomes depend on various factors. We have focused our work on gastrointestinal (GI) endoscopy because it is a cornerstone for diagnosis and treatment of diseases of the GI tract. Read More

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http://www.wjgnet.com/1007-9327/full/v24/i45/5057.htm
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http://dx.doi.org/10.3748/wjg.v24.i45.5057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288655PMC
December 2018
4 Reads

Hematemesis Due to Drug Allergy to Oral Prednisolone in a Patient with Ulcerative Colitis.

Intern Med 2018 Dec 18. Epub 2018 Dec 18.

Department of Gastroenterology, Dokkyo Medical University, Japan.

The patient was diagnosed with ulcerative colitis and received remission induction therapy with prednisolone. While they developed muscle pain in the lower extremities after starting prednisolone, they ultimately achieved clinical remission. After discharge, hematemesis and gastric discomfort developed. Read More

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https://www.jstage.jst.go.jp/article/internalmedicine/advpub
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http://dx.doi.org/10.2169/internalmedicine.1639-18DOI Listing
December 2018
7 Reads

Early detection of GI bleeding: "starting the clock for the capsule drop".

Gastrointest Endosc 2019 01;89(1):44-46

University of Pennsylvania Health Systems, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.gie.2018.08.024DOI Listing
January 2019

Response.

Gastrointest Endosc 2019 01;89(1):205

Section of Gastroenterology, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1016/j.gie.2018.08.036DOI Listing
January 2019

Short-type balloon-assisted endoscope for ERCP in patients with Roux-en-Y gastric bypass.

Gastrointest Endosc 2019 01;89(1):204-205

Third Department of Internal Medicine, Kansai Medical University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.gie.2018.08.002DOI Listing
January 2019
1 Read

Artificial intelligence and capsule endoscopy: Is the truly "smart" capsule nearly here?

Gastrointest Endosc 2019 01;89(1):195-197

Division of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S00165107183293
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http://dx.doi.org/10.1016/j.gie.2018.08.017DOI Listing
January 2019
5 Reads

Gaining traction: pulley-ing your weight during endoscopic submucosal dissection.

Gastrointest Endosc 2019 01;89(1):185-187

Division of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, Florida, USA.

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http://dx.doi.org/10.1016/j.gie.2018.09.021DOI Listing
January 2019

Gastric schwannoma: report of two cases and review of the literature.

Int J Surg Case Rep 2018 3;53:495-499. Epub 2018 Nov 3.

1st Propaedeutic Surgery Department, AHEPA University Hospital of Thessaloniki, Greece.

Introduction: Gastrointestinal schwannomas are benign, slow-growing and usually asymptomatic tumors. In some cases bleeding, epigastric pain and palpable mass may be occurring. Preoperative diagnosis is challenging due to the difficulty of differentiation from other submucosal tumors. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.10.062DOI Listing
November 2018

Complicated duodenal-jejunal diverticulosis: case report.

G Chir 2018 Nov-Dec;39(6):395-398

Background: Bleedings such as melaena are related to diseases in the upper gastrointestinal tract. In 0.06% - 5% of cases these incidents are due to the presence of diverticula of the small intestine, which are asymptomatic and unrecognized in most patients and are only fully diagnosed in cases when complications occur. Read More

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December 2018
1 Read

A huge gastric bezoar treated by traditional Chinese medicine purgative: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13712

Department of Gastroenterology, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, China.

Rationale: Currently, the mainstream treatment for gastric bezoars is endoscopic lithotripsy. This report describes traditional Chinese medicine (TCM) purgative cured a 62-year-old woman with a huge gastric bezoar accompanied by isolated esophageal venous aneurysms and multiple bleeding gastric ulcers.

Patient Concerns: A 62-year-old woman with several symptoms, including epigastric pain, nausea, and vomiting, hiccups, heartburn, and dark, loose stools. Read More

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http://Insights.ovid.com/crossref?an=00005792-201812140-0012
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http://dx.doi.org/10.1097/MD.0000000000013712DOI Listing
December 2018
8 Reads

Endoscopic ultrasound-guided internalization of a pancreaticocutaneous fistula utilizing a balloon-target technique: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13564

Rationale: Endoscopic ultrasound (EUS)-guided treatment has been recently described for internalizing refractory pancreaticocutaneous fistulas (PCFs). However, the existing techniques are limited because of the difficulty in accessing nondilated pancreatic ducts or fistulas. In an attempt to overcome this limitation, we present a case where a EUS-guided intervention utilizing a balloon-target technique was employed to internalize a PCF into the stomach. Read More

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http://dx.doi.org/10.1097/MD.0000000000013564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320205PMC
December 2018
1 Read

Primary gastric inflammatory myofibroblastic tumor: A case report.

Medicine (Baltimore) 2018 Dec;97(50):e13423

Department of Radiology, The First Affiliated Hospital, Nanchang University, Nanchang, Jiangxi, People's Republic of China.

Rationale: Primary gastric inflammatory myofibroblastic tumor is extremely rare. Only a few cases were reported in the domestic and foreign medical literature with corresponding imaging findings of this disease even more rarely reported.

Patient Concerns: We present one case of a 52-year-old female patient with upper abdominal pain, acid reflux, and belching for 2 months. Read More

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http://dx.doi.org/10.1097/MD.0000000000013423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320093PMC
December 2018
1 Read
5.723 Impact Factor

Hemobilia caused by pancreatic arteriovenous malformation: A case report and literature review.

Medicine (Baltimore) 2018 Dec;97(50):e13285

Department of General Surgery, China-Japan Friendship Hospital, Beijing 100029, China.

Rationale: Hemobilia caused by arteriovenous malformation is extremely rare but could be lethal. To date, most reports have been single-case reports, and no literature reviews are available.

Patient Concerns: A 47-year-old man presented to the emergency department with abdominal pain and fever. Read More

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http://dx.doi.org/10.1097/MD.0000000000013285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320063PMC
December 2018

Subtyping of intraductal papillary mucinous neoplasms - pitfalls of MUC1 immunohistochemistry.

APMIS 2019 Jan 22;127(1):27-32. Epub 2018 Nov 22.

Department of Pathology, Copenhagen University Hospital Rigshospitalet, København, Denmark.

Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic ductal adenocarcinoma (PDAC). Current edition of WHO Classification of Tumors of the Digestive System recognizes four different subtypes (gastric, intestinal, pancreatobiliary, and oncocytic) and recommends analysis of mucin expression (MUC1, MUC2, MUC5AC, MUC6) as well as evaluation of architectural and cell differentiation patterns for correct classification. However, there is no consensus on MUC1 expression of IPMN-lesions in the literature. Read More

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http://dx.doi.org/10.1111/apm.12900DOI Listing
January 2019
1 Read

Endoscopic submucosal dissection followed by chemoradiotherapy for superficial esophageal cancer: choice of new approach.

Radiat Oncol 2018 Dec 14;13(1):246. Epub 2018 Dec 14.

Department of Radiology, Kyoto Prefectural University Graduate School of Medical Science, 465 Kajiicho Kawaramachi Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.

Background: The standard treatment for superficial esophageal cancer (SEC) involving muscularis mucosal (T1a-MM) or submucosal (T1b) invasion has been the surgical resection of the esophagus. However, esophagectomy with extended lymph node dissection is highly invasive. Recent reports have shown that endoscopic submucosal dissection (ESD) followed by chemoradiotherapy (CRT) has promising results and might become a new therapeutic approach. Read More

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http://dx.doi.org/10.1186/s13014-018-1195-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295044PMC
December 2018