118,187 results match your criteria Esophagogastroduodenoscopy

United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on gastroparesis.

United European Gastroenterol J 2021 Apr;9(3):287-306

Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.

Background: Gastroparesis is a condition characterized by epigastric symptoms and delayed gastric emptying (GE) rate in the absence of any mechanical obstruction. The condition is challenging in clinical practice by the lack of guidance concerning diagnosis and management of gastroparesis.

Methods: A Delphi consensus was undertaken by 40 experts from 19 European countries who conducted a literature summary and voting process on 89 statements. Read More

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United European Gastroenterology (UEG) and European Society for Neurogastroenterology and Motility (ESNM) consensus on functional dyspepsia.

United European Gastroenterol J 2021 Apr;9(3):307-331

Gastroenterology Unit, Departmento of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.

Background: Functional dyspepsia (FD) is one of the most common conditions in clinical practice. In spite of its prevalence, FD is associated with major uncertainties in terms of its definition, underlying pathophysiology, diagnosis, treatment, and prognosis.

Methods: A Delphi consensus was initiated with 41 experts from 22 European countries who conducted a literature summary and voting process on 87 statements. Read More

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Correlation of Probe-Based Confocal Laser Endomicroscopy (pCLE) and Mucosal Integrity Testing (MIT) with Epithelial Barrier Function and Presence of Gastroesophageal Reflux Disease (GERD).

Dig Dis Sci 2021 May 3. Epub 2021 May 3.

Division of Gastroenterology, Hunter Holmes McGuire Richmond VA Medical Center, Gastroenterology # 111N, Richmond, VA, 23249, USA.

Introduction: Epithelial barrier function (EBF) disruption is a key mechanism underlying gastroesophageal reflux disease (GERD). Our aim was to assess whether two novel technologies, probe-based confocal laser endomicroscopy (pCLE) and mucosal integrity testing (MIT), could assess EBF.

Methods: We prospectively enrolled patients undergoing upper endoscopy for refractory GERD or non-GERD conditions. Read More

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The Effects of Patient Demographics on Outpatient Endoscopy Utilization in Children with Eosinophilic Esophagitis.

J Pediatr Gastroenterol Nutr 2021 Apr 28. Epub 2021 Apr 28.

Indiana University School of Medicine/Riley Hospital for Children, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition, 705 Riley Hospital Dr. ROC 4210, Indianapolis, IN 46202 Indiana University School of Medicine/Riley Hospital for Children, Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology, and Nutrition Indiana University School of Medicine/Riley Hospital for Children, Department of Pediatrics, Division of Asthma and Allergy.

Objectives: Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus that requires esophagogastroduodenoscopy (EGD) for diagnosis and treatment monitoring. We aimed to identify frequency of endoscopic monitoring in children with EoE and observe the effect of age, race, socioeconomic factors, and atopy on the rate of endoscopy.

Methods: We queried the Pediatric Health Information System over a 15-year period for ambulatory EGDs in children with EoE. Read More

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Crush cytology: an expeditious diagnostic tool for gastrointestinal tract malignancy.

Endosc Int Open 2021 May 22;9(5):E735-E740. Epub 2021 Apr 22.

Department of Clinical Research, Surat Institute of Digestive Sciences (SIDS), Surat, India.

 Crush cytology is a simple and rapid method used for diagnosis of central nervous system lesions. We have evaluated the diagnostic accuracy of crush cytology for gastrointestinal tract lesions.  This was a prospective, cross-sectional, single center study, conducted on the patients who had suspected malignant lesions between August 2018 and March 2020. Read More

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Composite detection rate as an upper gastrointestinal endoscopy quality measure correlating with detection of neoplasia.

J Gastroenterol 2021 May 2. Epub 2021 May 2.

Chair and department of Gastroenterology and Hepatology, School of Medicine in Katowice, Medical University of Silesia, Medyków 14 Street, 40-752, Katowice, Poland.

Background: Esophagogastroduodenoscopy (EGD) is commonly used diagnostic method with no widely accepted quality measure. We assessed quality indicator-composite detection rate (CDR)-consisting of detection of at least one of the following: cervical inlet patch, gastric polyp and post-ulcer duodenal bulb deformation. The aim of the study was to validate CDR according to detection rate of upper gastrointestinal neoplasms (UGN). Read More

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Cancer-associated fibroblasts-derived exosomes upregulate microRNA-135b-5p to promote colorectal cancer cell growth and angiogenesis by inhibiting thioredoxin-interacting protein.

Cell Signal 2021 Apr 28:110029. Epub 2021 Apr 28.

Ultrasonic diagnosis center, Hwa Mei Hospital, University of Chinese Academy of Sciences, Ningbo 315010, Zhejiang, China. Electronic address:

Objective: The role of exosomes in human cancers has been identified, while the effect of cancer-associated fibroblasts (CAFs)-derived exosomes (CAF-exos) transmitting microRNAs (miRNAs) on colorectal cancer (CRC) remains largely unknown. We aim to explore the impact of CAF-derived exosomal miR-135b-5p on CRC progression by targeting thioredoxin-interacting protein (TXNIP).

Methods: CRC tissues were collected to obtain CAF-exos, which were used to co-culture with LoVo and HT29 cells. Read More

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Positive Bronchoalveolar Lavage Pepsin Assay Associated with Viral and Fungal Respiratory Infections in Children with Chronic Cough.

Pediatr Pulmonol 2021 Apr 30. Epub 2021 Apr 30.

Pediatric Pulmonary and Sleep Medicine, Children's National Hospital, Washington, DC, United States.

Objective: To assess the association between commonly obtained endoscopic and serologic data and bronchoalveolar lavage pepsin assay (BAL) results in children with chronic cough.

Study Design: We performed a retrospective chart review of seventy-two children with a BAL pepsin obtained through our Aerodigestive Center over an 18-month period. BAL outcomes include evidence of viral, bacterial, or fungal infection, presence of lipid laden macrophages, and cytology (eosinophils, neutrophils, and lymphocytes). Read More

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ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding.

Am J Gastroenterol 2021 May;116(5):899-917

Division of Gastroenterology and Farncombe Family Digestive Health Research Institute, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

We performed systematic reviews addressing predefined clinical questions to develop recommendations with the GRADE approach regarding management of patients with overt upper gastrointestinal bleeding. We suggest risk assessment in the emergency department to identify very-low-risk patients (e.g. Read More

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External Validation of Blue Light Imaging (BLI) Criteria for the Optical Characterization of Colorectal Polyps by Endoscopy Experts.

J Gastroenterol Hepatol 2021 Apr 30. Epub 2021 Apr 30.

Department of Gastroenterology, Kansas City VA Medical Center, Kansas City, Missouri.

Background & Aims: Recently, the BASIC (BLI adenoma serrated international classification) system was developed by European experts to differentiate colorectal polyps. Our aim was to validate the BASIC classification system among the USA based endoscopy experts.

Methods: Participants utilized a web-based interactive learning system where the group was asked to characterize polyps using the BASIC criteria: polyp surface (presence of mucus, regular/irregular and [pseudo]depressed), pit appearance (featureless, round/non-round with/without dark spots; homogeneous/heterogeneous distribution with/without focal loss), and vessels (present/absent, lacy, peri-cryptal, irregular). Read More

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Risk factors for complications of therapeutic endoscopy for upper gastrointestinal subepithelial lesions.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2021 Mar;46(3):278-282

Department of Gastroenterology, Third Xiangya Hospital, Central South University, Changsha 410013, China.

Objectives: To study the risk factors for complications after endoscopic therapy for upper gastrointestinal subepithelial lesions (SELs).

Methods: Retrospective analysis was performed on 184 patients in the Department of Gastroenterology in the Third Xiangya Hospital, Central South University after therapeutic endoscopy [endoscopic submucosal dissection (ESD), endoscopic full-thickness resection (EFR), endoscopic submucosal excavation (ESE), and submucosal tunneling endoscopic resection (STER)] for the upper gastrointestinal SELs from 2014-09-01 to 2019-09-30. The clinic data were collected and risk factors for postoperative complications were analyzed. Read More

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Unsupervised Monocular Depth Estimation for Colonoscope System Using Feedback Network.

Sensors (Basel) 2021 Apr 11;21(8). Epub 2021 Apr 11.

School of Electronics and Information Engineering, Korea Aerospace University, Goyang 10540, Korea.

A colonoscopy is a medical examination used to check disease or abnormalities in the large intestine. If necessary, polyps or adenomas would be removed through the scope during a colonoscopy. Colorectal cancer can be prevented through this. Read More

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Overview of Prognostic Systems for Hepatocellular Carcinoma and ITA.LI.CA External Validation of MESH and CNLC Classifications.

Cancers (Basel) 2021 Apr 2;13(7). Epub 2021 Apr 2.

Division of Semeiotics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.

Prognostic assessment in patients with HCC remains an extremely difficult clinical task due to the complexity of this cancer where tumour characteristics interact with degree of liver dysfunction, patient general health status, and a large span of available treatment options. Several prognostic systems have been proposed in the last three decades, both from the Asian and European/North American countries. Prognostic scores, such as the CLIP score and the recent MESH score, have been generated on a solid statistical basis from real life population data, while staging systems, such as the BCLC scheme and the recent CNLC classification, have been created by experts according to recent HCC prognostic evidences from the literature. Read More

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Outcomes of 100 Patients Greater than 4 Years after POEM for Achalasia.

Ann Surg 2021 Feb 26. Epub 2021 Feb 26.

*Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois †Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Objective: We aim to describe the long-term follow up data from our institution's POEM experience.

Summary Background Data: Per-oral endoscopic myotomy (POEM) is a well-established endoscopic therapy for achalasia with excellent short-term efficacy, but long-term outcomes data are limited.

Methods: Patients greater than 4 years removed from POEM for treatment of achalasia were studied. Read More

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February 2021


Arq Gastroenterol 2021 Jan-Mar;58(1):71-76

Faculdade Santa Marcelina, São Paulo, Brasil.

Background: Hepatobiliary surgery and hepatic trauma are frequent causes of bile leaks and this feared complication can be safely managed by endoscopic retrograde cholangiopancreatography (ERCP). The approach consists of sphincterotomy alone, biliary stenting or a combination of the two but the optimal form remains unclear.

Objective: The aim of this study is to compare sphincterotomy alone versus sphincterotomy plus biliary stent placement in the treatment of post-surgical and traumatic bile leaks. Read More

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Prevalence, clinical features, and esophagogastroduodenoscopy (EGD) findings of non-Helicobacter pylori Helicobacter infection: A study of 50 cases at a single facility in Japan.

Helicobacter 2021 Apr 27:e12811. Epub 2021 Apr 27.

Department of Internal Medicine, Showainan General Hospital, Komagane, Japan.

Background And Aim: There are only a few reports of non-Helicobacter pylori Helicobacter (NHPH) gastritis in Japanese patients. We aimed to examine its prevalence, clinical features, and esophagogastroduodenoscopy (EGD) findings based on 50 patients encountered in one facility.

Materials And Methods: Subjects were all patients who had undergone gastric mucosal biopsy endoscopically at Kenwakai Hospital for approximately 10 years. Read More

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[Risk and control management of endoscopic retrograde cholangiopancreatography in patients with liver cirrhosis].

X M Li L G Lu X B Cai

Zhonghua Gan Zang Bing Za Zhi 2021 Mar;29(3):209-212

Department of Gastroenterology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200080, China.

Endoscopic retrograde cholangiopancreatography (ERCP) is the most direct and effective method for the diagnosis and treatment of biliary and pancreatic diseases. Compared with surgery, ERCP has the advantages of minimal trauma, shorter surgery time, fewer complications, and shorter hospital stay. Liver cirrhosis, as the advanced stage of liver disease, has reduced tolerance to surgical stresses, and complications such as hepatic encephalopathy, esophagogastric varices, and coagulation dysfunction may occur during the decompensated stage, which poses a challenge to ERCP, and thus increase the intraoperative risk and postoperative complications. Read More

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Small-bowel aspiration during upper esophagogastroduodenoscopy: Rao technique.

VideoGIE 2021 Apr 19;6(4):152-154. Epub 2020 Dec 19.

Digestive Health Center, Department of Medicine, Augusta University, Augusta, Georgia.

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Echoendoscopy in Preoperative Evaluation of Esophageal Adenocarcinoma and Gastroesophageal Junction: Systematic Review and Meta-analysis.

Ultrasound Med Biol 2021 Apr 22. Epub 2021 Apr 22.

Digestive Tract Surgery Service and Surgery Group of the Esophagus and Stomach of the Hospital de Clínicas de Porto Alegre (HCPA), Port Alegre, Rio Grande do Sul, Brazil; Department of Surgery, Faculty of Medicine, Federal University of Rio Grande do Sul (UFRGS), Port Alegre, Rio Grande do Sul, Brazil.

Esophageal adenocarcinomas of the esophagus and esophagogastric junction constitute a global health problem, the incidence of which has increased in recent decades. It has a poor prognosis and a low 5-year survival rate. Its treatment is based on preoperative clinical staging, in which echoendoscopy plays an essential role. Read More

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Plummer-Vinson Syndrome: A Rare Cause of Dysphagia in an Octogenarian.

Am J Case Rep 2021 Apr 24;22:e929899. Epub 2021 Apr 24.

Department of Gastroenterology, St. Luke's University Hospital Health Network, Bethlehem, PA, USA.

BACKGROUND Plummer-Vinson syndrome is a rare disease that presents with iron-deficiency anemia, dysphagia, and esophageal webs. It usually occurs in middle-aged White women, and it increases the risk for esophageal cancer. The prevalence of Plummer-Vinson syndrome has decreased due to early detection of iron deficiency and repletion of iron stores. Read More

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Prolonged survival of a patient with aortogastric fistula treated with combined surgery and endovascular stent placement: A case report.

Int J Surg Case Rep 2021 Apr 23;81:105815. Epub 2021 Mar 23.

Department of Surgery, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address:

Introduction: Aortogastric tube fistula is a rare and fatal complication of esophagectomy. The treatment for aortogastric tube fistula with active infection is challenging, wherein a contamination around the fistula can cause a high risk of aneurysm and recurrence of bleeding, even if large amount of bleeding is controlled immediately.

Presentation Of Case: We present a case of a 54-year-old male patient who underwent lower esophagectomy for esophageal squamous cell carcinoma 22 years ago. Read More

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Endoscopic full-thickness resection and post-procedural appendicitis: every advantage has its disadvantage.

Endoscopy 2021 05 22;53(5):561. Epub 2021 Apr 22.

Department of Gastroenterology and Hepatology, Imelda General Hospital, and Imelda Clinical GI Research Center, Bonheiden, and Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Belgium.

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Reply to Phillpotts and Webster.

Endoscopy 2021 05 22;53(5):560. Epub 2021 Apr 22.

Department of Gastroenterology, Graduate School of Medicine, Juntendo University, Tokyo, Japan.

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The role of endoscopic papillary large balloon dilatation without sphincterotomy.

Endoscopy 2021 05 22;53(5):559. Epub 2021 Apr 22.

Department of Gastroenterology, University College London Hospitals NHS Foundation Trust, London, UK.

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Are balloon enteroscopy-assisted ERCP and laparoscopy-assisted ERCP in Roux-en-Y gastric bypass equivalent?

Endoscopy 2021 05 22;53(5):558. Epub 2021 Apr 22.

Pancreaticobiliary Unit, University College London Hospitals, London, UK.

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Doing our best to do no harm.

Uri Ladabaum

Endoscopy 2021 05 22;53(5):509-510. Epub 2021 Apr 22.

Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California, United States.

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Transabdominal ultrasonography to reduce the burden of X-ray imaging in prophylactic pancreatic stent localization after ERCP-A prospective trial.

United European Gastroenterol J 2021 Apr 22. Epub 2021 Apr 22.

Department of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, Germany.

Background: Before performing endoscopy to remove prophylactic pancreatic stents placed in patients with high risk of post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP), X-ray imaging is recommended to confirm the stents position in the pancreatic duct.

Objectives: The aim of the present study was to investigate the feasibility of prophylactic pancreatic stent detection by transabdominal ultrasonography, to reduce the burden of X-ray imaging, which is currently the golden standard.

Methods: All patients who received a pancreatic stent for PEP prophylaxis were included in the present prospective trial. Read More

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Episodic angioedema with eosinophilia (Gleich's syndrome) associated with urticarial vasculitis: a coincidence or a novel clinical entity?

Braz J Med Biol Res 2021 19;54(6):e10745. Epub 2021 Apr 19.

Departamento de Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brasil.

Episodic angioedema with eosinophilia (EAE) is a rare condition characterized by recurrent attacks of angioedema and urticaria accompanied by a marked elevation of peripheral eosinophil count. We report the case of a young female patient diagnosed with EAE associated with urticarial vasculitis. A 40-year-old female patient was admitted to our institution due to recurrent episodes of cheek and eyelid angioedema in the previous year. Read More

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Localized gastric amyloidosis diagnosed by endoscopic ultrasound-guided fine-needle aspiration.

Clin J Gastroenterol 2021 Apr 22. Epub 2021 Apr 22.

Department of Gastroenterology, Fukushima Medical University School of Medicine, Fukushima, Japan.

A 49-year-old man was found to have an elevated lesion on esophagogastroduodenoscopy (EGD) for gastric cancer screening. This lesion had been noted in EGD 13 years earlier, but the patient had not received EGD since then. Endoscopy showed a relatively soft subepithelial lesion (SEL) in the gastric antrum. Read More

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Refractory Effusions, Crumbly Bones, Mystifying Cachexia and an Absent Mind: An Unusual Presentation of Whipple's Disease with Review of Literature.

Am J Med Case Rep 2021 1;9(7):348-353. Epub 2021 Apr 1.

Department of Medicine, State University of New York, Downstate Health Sciences University, Brooklyn, NY.

Whipple's disease is a bacterial infection caused by Tropheryma whipplei and is known to cause perplexing clinical presentations, making its diagnosis challenging. The beginning by the involvement of the gastrointestinal tract, Whipple's disease can slowly progress to affect almost any organ system and lead to chronic multi-system inflammatory disease. Hereby, we present a middle age man who initially manifested with shortness of breath and chronic weight loss. Read More

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