Search Our Scientific Publications & Authors

Curr Opin Gastroenterol 2020 Jun 28. Epub 2020 Jun 28.

Digestive Diseases Center, Showa University Koto Toyosu Hospital, Tokyo, Japan.

Purpose Of Review: Benign strictures of the esophagus, caused by various causes, are frequently encountered in clinical practice. Although endoscopic dilation is still the standard and first-line therapy, complex and difficult esophageal strictures are still encountered and remain a challenge to endoscopists. The main scope of this review article is to offer a closer look at the different endoscopic modalities and approaches to complex and difficult esophageal strictures. Read More

Arch Public Health 2020 30;78:61. Epub 2020 Jun 30.

Latin-American Institute of Life and Natural Sciences, Federal University of Latin-American Integration, Foz do Iguassu, Parana Brazil.

Background: Major birth defects increase the risk of fetal death and pediatric hospitalization, which also impact on healthcare costs. Sociodemographic factors can drastically affect reproductive health and be used to discriminate the exposure to hidden risk factors. Foz do Iguassu is a Brazilian city located in the triple-border region of Brazil / Paraguay / Argentina with high rates of birth defects. Read More

Sisli Etfal Hastan Tip Bul 2020 15;54(2):176-180. Epub 2020 May 15.

Department of Pediatric Surgery, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey.

Objectives: Household chemicals result in corrosive esophageal burns in the developing third world countries, and most of them cause esophageal strictures. There is no standard treatment for esophageal strictures. Here, we present our preliminary experience with intraluminal esophageal stents for stricture treatment. Read More

Saudi Med J 2020 Jul;41(7):720-725

Department of Surgery, Faculty of Medicine, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia. E-mail.

Objectives: To report the results of endoscopic dilatation of esophageal strictures in children, its complications, and their management. The outcomes of esophageal dilatation differ according to the underlying etiology.

Methods: The study included 46 patients who underwent esophageal dilatation between 2014-2019. Read More

J Surg Case Rep 2020 Jun 19;2020(6):rjaa183. Epub 2020 Jun 19.

Department of General Surgery, Damascus University, Damascus, Syria.

Sleeve gastrectomy (SG) is an effective method for weight loss; it is done by laparoscopy or open approach; it is a restrictive procedure and involves removing part of the stomach by cutting over bougie, which ensures that stenosis doesn't occur. Bougie may cause esophageal perforation. There are studies that show the size of bougie used and weight loss are related. Read More

Klin Padiatr 2020 Jun 26. Epub 2020 Jun 26.

Department of Pediatric Surgery, University Hospital Leipzig, Leipzig.

Esophageal atresia (EA) is a congenital anomaly that entails an interrupted esophagus with or without tracheoesophageal fistula (TEF). Depending on the distance of the two esophageal pouches a "short-gap" is distinguished from a "long-gap" variant. Up to 50% of newborns have additional anomalies. Read More

J Formos Med Assoc 2020 Jun 22. Epub 2020 Jun 22.

Department of Pediatrics, National Taiwan University Hospital, National Taiwan University, Taipei, Taiwan. Electronic address:

Background/purpose: Anastomotic stricture (AS) is a major morbidity of patients with esophageal atresia (EA) after surgical reconstruction. Our study determined the risk factors of AS after EA reconstruction. The therapeutic efficacy and complications of esophageal dilatation for children with AS were also evaluated. Read More

Eur Arch Otorhinolaryngol 2020 Jun 24. Epub 2020 Jun 24.

Department of Otorhinolaryngology - Head and Neck Surgery, University of Padua, Padua, Italy.

Introduction: Salvage total laryngectomy (STL) is the most common treatment for recurrent laryngeal cancer after (chemo)-radiotherapy [(C)RT]. In this scenario, a higher rate of local wound complications, such as pharyngo-cutaneous fistula (PCF) and pharyngo-esophageal stenosis (PES), is generally expected. The aim of the present study is to evaluate outcomes using a standardized reconstructive protocol. Read More

J Indian Assoc Pediatr Surg 2020 May-Jun;25(3):155-162. Epub 2020 Apr 11.

Department of Pediatrics, Sarkar Hospital for Women and Children, Agra, Uttar Pradesh, India.

Aims: We are reporting single-institution's experience regarding the role of conservative management in 38 cases of minor and major anastomotic leaks [AL] occurring after primary surgery of esophageal atresia [EA] with tracheo-esophageal fistula [TEF] during last 17 years between 2000 and 2017. In this retrospective review, we are sharing our experience and protocol of management of AL with more emphasis to evaluate: (a) role of conservative treatment in major AL (b) role of extra-pleural approach in enhancing the success rate in conservative treatment in major AL (c) to define the criteria for major & minor leaks and (d) to evaluate the role of ventilation in primary EA surgery to control AL.

Methods: All these cases were operated through extra-pleural approach and out of total 203 cases, 38[18. Read More

Digestion 2020 Jun 22:1-15. Epub 2020 Jun 22.

Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin, China,

Background: Eosinophilic esophagitis (EoE) is an immune-mediated clinicopathological condition characterized by esophageal infiltration with eosinophils resulting in chronic inflammation and stricture.

Summary: The recent increase in the incidence of EoE and the characteristic presentation of symptoms with difficulty swallowing and food bolus impaction has raised key concerns of clinicians as well as researchers. EoE often presents with dysphagia, food impaction, nausea, regurgitation or vomiting, and decreased appetite. Read More

Dis Esophagus 2020 Jun 22. Epub 2020 Jun 22.

Division of Gastroenterology and Hepatology, Mayo Clinic Arizona.

Distal esophageal spasm (DES) is a motility disorder characterized by premature contraction of the esophageal body during single swallows. It is thought to be due to impairment of esophageal inhibitory pathways, but studies to support this are limited. The normal response to multiple rapid swallows (MRS) is deglutitive inhibition of the esophageal body during the MRS sequence. Read More

Therap Adv Gastroenterol 2020 10;13:1756284820927282. Epub 2020 Jun 10.

Department of Health Services Research, Durham University, Durham, UK.

Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of the esophagus characterized by symptoms of esophageal dysfunction and eosinophil-predominant inflammation. The incidence of EoE has increased substantially over the past two decades in Europe and North America. The natural course of EoE appears to be progressive with a high risk of stricture formation. Read More

J Surg Res 2020 Jun 18;255:195-204. Epub 2020 Jun 18.

Department of Orthopedics, the First Affiliated Hospital, Zhengzhou University, Zhengzhou, China.

Background: Most surgeons now accept lymphadenectomy as an essential feature of the operative treatment of esophageal squamous cell carcinoma. Three-field and two-field lymphadenectomy are two of the most popular excision scopes among surgeons. Over recent years, researchers have performed a range of comparative studies regarding these techniques, although the conclusions remain inconsistent. Read More

Surg Endosc 2020 Jun 15. Epub 2020 Jun 15.

Department of Surgery, Faculty of Medicine, Thammasat University (Rangsit Campus), 99/209 Moo 18, Paholyothin Road, Amphur Klongluang, Pathumthani, 12120, Thailand.

Objectives: Esophageal stricture is a significant complication of grade 2b and 3a esophageal injuries and causes much patient suffering. Preventing strictures would be beneficial to patients but there are currently no proven effective drugs. This study aimed to evaluate the effect of omeprazole for preventing esophageal stricture in adults with grade 2b and 3a corrosive esophageal injuries. Read More

ACG Case Rep J 2020 Apr 7;7(4):e00348. Epub 2020 Apr 7.

Department of Internal Medicine, Baylor College of Medicine, Houston, TX.

Caustic ingestions represent a well-known public health concern. Ingestion of highly alkali agents (lye ingestion) from the consumption of cleaning products is common, with an estimated 200,000 cases reported annually in the United States. Long-term complications of lye ingestion include esophageal strictures, gastric stenosis, and cancer. Read More

World J Clin Cases 2020 Jun;8(11):2116-2126

Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

Achalasia is a type of esophageal motility disorder, consisting of relaxation dysfunction of the lower esophagus and disturbed esophageal peristalsis. Related clinical symptoms include dysphagia, regurgitation, chest pain, and weight loss. Traditional treatment options include endoscopic botulinum toxin injection, endoscopic pneumatic dilation, and laparoscopic Heller's myotomy. Read More

J Pediatr Gastroenterol Nutr 2020 Jun 11. Epub 2020 Jun 11.

Division of Pediatric Gastroenterology, Medical University of South Carolina, Charleston, South Carolina.

VideoGIE 2020 Jun 20;5(6):230-232. Epub 2020 Mar 20.

Department of Endoscopy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Therap Adv Gastroenterol 2020 26;13:1756284820923220. Epub 2020 May 26.

Digestive Endoscopy and Surgical Unit, Ospedale Pediatrico Bambino Gesù, Roma, Italy.

Background: Since the esophagus has no redundancy, congenital and acquired esophageal diseases often require esophageal substitution, with complicated surgery and intestinal or gastric transposition. Peri-and-post-operative complications are frequent, with major problems related to the food transit and reflux. During the last years tissue engineering products became an interesting therapeutic alternative for esophageal replacement, since they could mimic the organ structure and potentially help to restore the native functions and physiology. Read More

Eur Heart J Suppl 2020 Jun 30;22(Suppl E):E40-E45. Epub 2020 Mar 30.

Universita' Vita-Salute e Ospedale San Raffaele, IRCCS Milano, Italy.

Myocardial infarction in the absence of obstructive coronary stenosis (MINOCA) is a syndrome with several causes, characterized by clinical evidence of myocardial infarction and coronary angiographically normal or almost normal (stenosis ≤50%). MINOCAs represent about 10% of acute coronary syndromes. The causes of MINOCA are manifold and can be classified on the basis of the mechanism in epicardial (unstable plaque not manifested by angiography, epicardial spasm and coronary dissection) or microvascular. Read More

J Surg Res 2020 Jun 7;254:334-339. Epub 2020 Jun 7.

Department of Paediatric Surgery and Urology, Southampton Children's Hospital, Southampton, UK; University Surgery Unit, Faculty of Medicine, University of Southampton, Southampton, UK. Electronic address:

Background: Anastomotic stricture is a significant cause of morbidity after repair of esophageal atresia (EA). Exposure to gastric acid has been postulated to contribute to stricture development and severity leading to prophylactic antacid use by some surgeons. We investigated the association between administration of antacid medication and the development of anastomotic strictures. Read More

World J Clin Cases 2020 May;8(10):1950-1957

Department of Radiation Oncology, National University Cancer Institute, National University Hospital, Tan Tock Seng Hospital, Singapore 119228, Singapore.

Background: T4 esophageal cancer portends a poor prognosis, particularly when it is complicated by a tracheoesophageal fistula (TEF) either resulting from disease or occurring as a complication of treatment. Patients with TEF that occurs during treatment are commonly treated with palliative intent because fistula-associated treatment complications such as aspiration pneumonia and mediastinitis are associated with high morbidity and mortality. To date, there is no clear evidence on the optimal treatment of T4 esophageal cancer, particularly when a TEF formation occurs. Read More

Clin J Gastroenterol 2020 Jun 8. Epub 2020 Jun 8.

Division of Gastroenterology, Department of Internal Medicine, School of Medicine, Iwate Medical University, Idaidori 1-1-1, Yahaba, 028-3694, Japan.

A 49 years old male, who had had postprandial dysphagia during the preceding 10 years, was referred to our hospital. Esophagogastroduodenoscopy (EGD) revealed longitudinal furrows and concentric rings in the mid to lower esophagus and stenosis in the lower esophagus. Histologic findings from esophageal biopsies showed eosinophilic infiltration (> 15 per high-power field). Read More

Clin J Gastroenterol 2020 Jun 8. Epub 2020 Jun 8.

Division of Gastroenterology, St. Luke's International Hospital, 9-1 Akashi-cho, Chuo-ku, Tokyo, 104-8340, Japan.

Although endoscopic submucosal dissection has been increasingly performed for managing superficial esophageal carcinomas, the risk of post-operative esophageal stenosis remains. Endoscopic balloon dilation for esophageal stenosis is the most common cause of esophageal perforation. Esophageal perforation complicated with mediastinal abscess and sepsis has a high mortality rate. Read More

JGH Open 2020 Jun 29;4(3):472-476. Epub 2019 Nov 29.

Department of Gastroenterology, Sir Sunderlal Hospital, Institute of Medical Sciences Banaras Hindu University Varanasi India.

Background And Aim: Dysphagia can lead to substantial morbidity and mortality, especially in the elderly. It has both benign and malignant causes. Despite having a varied etiology, there have been few studies in India. Read More

Eur Arch Otorhinolaryngol 2020 Jun 6. Epub 2020 Jun 6.

Department of Otorhinolaryngology, Head and Neck Surgery, IRCCS Ospedale Policlinico San Martino, Largo R. Benzi 10, 16132, Genoa, Italy.

Introduction: The novel Coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2, may need intensive care unit (ICU) admission in up to 12% of all positive cases for massive interstitial pneumonia, with possible long-term endotracheal intubation for mechanical ventilation and subsequent tracheostomy. The most common airway-related complications of such ICU maneuvers are laryngotracheal granulomas, webs, stenosis, malacia and, less commonly, tracheal necrosis with tracheo-esophageal or tracheo-arterial fistulae.

Materials And Methods: This paper gathers the opinions of experts of the Laryngotracheal Stenosis Committee of the European Laryngological Society, with the aim of alerting the medical community about the possible rise in number of COVID-19-related laryngotracheal stenosis (LTS), and the aspiration of paving the way to a more rationale concentration of these cases within referral specialist airway centers. Read More

J Cardiothorac Surg 2020 Jun 5;15(1):125. Epub 2020 Jun 5.

Department of Thoracic Surgery, Hebei General Hospital, 348,West He-Ping Road, Shijiazhuang, 050051, Hebei Province, People's Republic of China.

Background: Transthoracic esophagectomy is a crucial independent risk factor for the incidence of postoperative cardiopulmonary complications in elderly or comorbid patients. To reduce postoperative cardiopulmonary complications and promote postoperative recovery. We made an attempt to adopt the single-port inflatable mediastinoscopy combined with laparoscopy for radical esophagectomy in esophageal cancer to observe the clinical application and effect. Read More

Ann Palliat Med 2020 May;9(3):1206-1210

Gastroenterology and Center of Digestive Endoscopy, the Second Hospital of Jilin University, Changchun 130041, China.

Background: Benign anastomotic esophageal stricture after surgical resection frequently occurs and requires endoscopic balloon dilation (EBD) or incision to maintain patency because of the significant recurrence rate. Our study was designed to evaluate the effectiveness and safety of endoscopic incision and selective cutting (EISC) as primary treatment on 5 patients for benign anastomotic esophageal stricture.

Methods: Five patients with benign stricture of the esophageal anastomosis after radical resection for esophageal cancer underwent EISC in our center between April, 2018 and January, 2019. Read More

Cureus 2020 May 1;12(5):e7909. Epub 2020 May 1.

Medical Gastroenterology, Mathura Das Mathur Hospital, Jodhpur, IND.

Corrosive-induced stricture of the digestive tract is a dreaded complication following corrosive ingestion. When surgical reconstruction is needed, esophagectomy helps to avoid the long-term complications related to leaving behind the scarred native esophagus. We tried to ascertain the feasibility and safety of a thoracolaparoscopic-assisted esophagectomy in such a setting. Read More

Cureus 2020 Apr 30;12(4):e7898. Epub 2020 Apr 30.

Hematology and Oncology, Ashland Bellefonte Cancer Center, Ashland, USA.

Eosinophilic esophagitis (EoE) is a clinicopathological condition characterized clinically by symptoms of esophageal dysfunction, with typical endoscopic findings and intra-epithelial eosinophilia on biopsy. This case report focuses on the historical aspect of EoE, clinical manifestations, and correlation with immune disorders, medical management, and interventional management of EoE. We present a 20-year-old patient presenting with tightness in throat and odynophagia after the ingestion of certain foods. Read More

BMC Pediatr 2020 Jun 3;20(1):267. Epub 2020 Jun 3.

Department of Pediatric Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Background: The aim of this study was to evaluate anastomotic complications after primary one-staged esophageal atresia (EA) repair relating to the patients` gestational age (GA).

Methods: Retrospective data analyses of patients who underwent closure of tracheoesophageal fistula (TEF) and primary esophageal anastomosis from 01/2007 to 12/2018 in two pediatric surgical centers. Exclusion of EA other than Gross type C, long-gap EA, minimal invasive or staged approach. Read More

World Neurosurg 2020 May 31. Epub 2020 May 31.

Department of Neurosurgery, Virginia Commonwealth University Health System, Richmond, VA, USA.

Tapia syndrome is a rare complication of surgical positioning with resulting unilateral cranial nerve X and XII deficits that may provide diagnostic challenges in the peri-operative period. Timely diagnosis will facilitate obtaining the necessary supportive care while preventing unnecessary work-up and procedures. The following case report illustrates a patient that developed Tapia Syndrome immediately following a posterior cervical laminoplasties with eventual resolution of symptoms. Read More

Medicine (Baltimore) 2020 May;99(22):e20498

Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jianshe Rd, Zhengzhou, Henan Province.

To explore the outcome of placing a single Y-shaped tracheal self-expandable metallic stent (SEMS) to treat emergent carinal stenosis combined with stenosis of the right main and intermediate bronchi.The clinical and imaging data of 10 patients (8 males, 2 females) with carinal stenosis combined with stenosis of the right main and intermediate bronchi were retrospectively analyzed. There were 4 patients with esophageal cancer and 6 patients with lung cancer. Read More

Clin Case Rep 2020 May 9;8(5):919-922. Epub 2020 Mar 9.

Department of Gastroenterology Saitama Medical Center Jichi Medical University Saitama Japan.

Antiangiogenic agents, such as ramucirumab, should be cautiously administered along with radiotherapy because of the enhanced risk of adverse events. Read More

Gastric Cancer 2020 May 31. Epub 2020 May 31.

Department of Surgery, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

Background: Laparoscopic and endoscopic cooperative surgery (LECS) technique for gastric submucosal tumor (SMT) has developed, but treatment of SMT on the esophagogastric junction (EGJ) remains technically difficult because excessive resection may result in postoperative transformation of the EGJ and cause stenosis, and intervention to lower esophageal sphincter may result in gastroesophageal reflux. The study aim was to evaluate the feasibility and safety of LECS for SMT on the EGJ.

Methods: Between September 2012 and December 2018, LECS was performed for 21 patients with SMTs on the EGJ. Read More

Surg Endosc 2020 Aug 28;34(8):3560-3566. Epub 2020 May 28.

Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Background: Endoscopic submucosal dissection (ESD) has a favorable outcome, compared to esophagectomy, for early esophageal neoplasia. Recent studies used general anesthesia for esophageal ESD to minimize complications due to insufficient sedation and patient movement. We aimed to evaluate the safety of general anesthesia in comparison with conscious sedation provided by anesthesiologists for esophageal ESD. Read More

J Pediatr Surg 2020 Apr 29. Epub 2020 Apr 29.

Pediatric Surgery department, Ain Shams University, Cairo, Egypt.

Background: Caustic esophageal stricture length assessment is essential for planning endoscopic management and predicting its prognosis. We aimed to assess the accuracy of contrast swallow study (CSS) in measuring stricture length in comparison to endoscopy (definitive investigation for actual length measurement).

Method: Medical records of caustic esophageal strictures between 2010 and 2020 were retrospectively reviewed. Read More

Dis Esophagus 2020 May 28. Epub 2020 May 28.

Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, USA.

Anastomotic stricture is a common complication of esophageal atresia (EA) repair. Such strictures are managed with dilation or other therapeutic endoscopic techniques such as steroid injections, stenting, or endoscopic incisional therapy (EIT). In situations where endoscopic therapy is unsuccessful, patients with refractory strictures may require surgical stricture resection; however, the point at which endoscopic therapy should be abandoned in favor of repeat thoracotomy is unclear. Read More

IDCases 2020 11;21:e00795. Epub 2020 May 11.

Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa.

Cytomegalovirus (CMV) esophagitis is well described in immunocompromised individuals, however, esophageal stricture due to CMV is rare. CMV disease in the setting of the immune reconstitution inflammatory syndrome (IRIS) usually takes the form of an immune-recovery uveitis or retinitis. We describe a young female patient with HIV who developed an esophageal stricture due to CMV within 6 months of starting antiretroviral therapy (ART). Read More

Clin J Gastroenterol 2020 May 24. Epub 2020 May 24.

Department of Surgery, Kochi Medical School, Nankoku, Kochi, 783-8505, Japan.

Aortoesophageal fistula (AEF) is a highly life-threatening condition, even when treated promptly. However, little is known about the treatment for AEF in patients with advanced esophageal cancer. We report the case of a 69-year-old man diagnosed with esophageal squamous cell carcinoma (ESCC) that was admitted to our hospital for ESCC treatment. Read More

J Pediatr Surg 2020 Apr 28. Epub 2020 Apr 28.

All India Institute of Medical Sciences, New Delhi, India, PIN 110029. Electronic address:

Objectives: The authors herein report the results of esophageal replacement by gastric pull-up technique through the retrosternal route as an option for esophageal replacement in a resource-constrained setup.

Method: Prospectively collected data upon twenty-two consecutive patients (male:female = 17:5) with mean age 24.9 months (7 months-12 years) and mean weight 7. Read More

Clin Perinatol 2020 Jun 5;47(2):413-422. Epub 2020 Mar 5.

Division of Gastroenterology, Hepatology and Nutrition, Nationwide Children's Hospital, The Ohio State University College of Medicine, 700 Children's Drive, Columbus, OH 43205, USA.

Gastrointestinal endoscopy permits direct observation of the alimentary tract, acquisition of mucosal tissue for histopathologic examination, and other diagnostic and therapeutic maneuvers. Endoscopes of appropriate size for many neonates and an expanding array of compatible tools and accessories have broadened what is possible, although few neonatal data exist to guide use. Evaluation and treatment of gastrointestinal bleeding, evaluation and dilation of fibromuscular congenital esophageal stenosis, and the bedside placement of gastrostomy tube have been described. Read More

Dig Endosc 2020 May 20. Epub 2020 May 20.

Department of Clinical oncology, Kyoto University, Kyoto, Japan.

Objectives: Photodynamic therapy (PDT) is an effective salvage endoscopic treatment for local failure at the primary site after chemoradiotherapy (CRT) in esophageal cancer patients. However, the contribution of local control by salvage PDT to the prognosis is unclear. We investigated whether complete response at primary site by salvage PDT could improve the prognosis. Read More

Clin Gastroenterol Hepatol 2020 May 17. Epub 2020 May 17.

Division of Gastroenterology and Hepatology, Mayo Clinic, Jacksonville, Florida, The United States.

Background & Aims: Radiofrequency ablation (RFA) is the most common treatment for flat Barrett's esophagus (BE), but reasons for varying outcomes are poorly understood. A recently developed contrast-enhancement algorithm allows reliable measurement of Barrett's epithelial thickness (BET) from volumetric laser endomicroscopy (VLE) images and correlation with response to RFA. Using this algorithm, we investigated whether patients with thicker Barrett's mucosa are less likely to respond to RFA. Read More

Pediatr Int 2020 May 20. Epub 2020 May 20.

Department of Surgery, Pediatric Surgery Division, School of Medicine, University of Jordan, Amman, Jordan.

Background: Esophageal atresia is a developmental disorder in which the upper and lower esophagus fail to connect. It has an estimated prevalence of 1 in 2500-4500 live births and has poorer outcomes in low- and middle-income countries compared to those in high-income countries. This study focused on the disorder's epidemiology, morbidity and mortality in Jordan in order to address the lack of data regarding esophageal atresia in this country. Read More

Surg Endosc 2020 May 19. Epub 2020 May 19.

Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, 180 FengLin Road, Shanghai, 200032, People's Republic of China.

Background: The surgery for esophageal cancer arising after prior gastrectomy is technically difficult with high morbidity and mortality. Endoscopic submucosal dissection (ESD) is a minimally invasive endoscopic treatment for superficial SCC with high curative resection rate. But few studies are concerned about ESD under these circumstances. Read More

J Clin Med 2020 May 17;9(5). Epub 2020 May 17.

First Department of Medicine, Hamamatsu University School of Medicine, 1-20-1 Handayama, Higashi-ku, Hamamatsu 431-3192, Japan.

A phase II study of second-generation photodynamic therapy (PDT) using talaporfin sodium has shown excellent treatment results for esophageal cancer with local failure after chemoradiotherapy (CRT) or radiotherapy (RT). However, only a few studies have reported this therapy in clinical practice. This study aimed to confirm the efficacy and safety of salvage PDT using talaporfin sodium for esophageal cancer in various clinical situations. Read More

Radiother Oncol 2020 Jun 15;147:169-177. Epub 2020 May 15.

Institute for Translational Medicine, Medical School, Szentágothai Research Centre, University of Pécs, Hungary. Electronic address:

Aim: To compare the efficacy and safety of stent insertion alone to stent insertion combined with any active oncological treatment in the palliative care of esophageal cancer.

Methods: A meta-analysis and systematic review were performed according to the PRISMA Statement. Comparative studies with patients receiving stent insertion alone (control group) were compared to patients receiving oncological therapy in addition to stent placement (intervention group). Read More

Gland Surg 2020 Apr;9(2):417-422

Department of Gastroenterology and Hepatology, Chinese PLA General Hospital, Medical School of Chinese PLA, Beijing 100853, China.

Esophageal metastasis of primary breast cancer is rare, with nearly all the literature on this topic consisting of case report studies. When breast cancer patients complain of progressive dysphagia after a long disease-free interval after breast surgery, they may be treated and misdiagnosed with a second primary. Our aim was to review all the literature concerning esophageal metastasis of breast cancer, for the purpose of improving the awareness in identifying these patients and providing them proper treatment. Read More

Int J Surg Case Rep 2020 11;70:140-144. Epub 2020 May 11.

Department of Otorhinolaryngology, Sano Kosei General Hospital, 1728 Horigomecho, Sano City, Tochigi, Japan.

Introduction: Sarcopenic dysphasia is a relatively new disease concept describing impairments in swallowing resulting from a generalized loss of skeletal muscle mass.

Presentation Of Case: In this case report, we describe the clinical history and presentation of a 76-year-old man who developed mild sarcopenic dysphasia following a period of physical inactivity after spinal stenosis surgery, which resulted in a loss of 10 kg of body weight in the 10-month period after surgery. The patient's dysphasia was managed with laryngeal suspension, performed via a minimally invasive thyromandibulopexy, in combination with rehabilitation and nutritional support. Read More