34,070 results match your criteria Esophageal Motility Disorders


Systematic Review of Pharyngeal and Esophageal Manometry in Healthy or Dysphagic Older Persons (>60 years).

Geriatrics (Basel) 2018 Oct 5;3(4). Epub 2018 Oct 5.

Department of Gastroenterology and Hepatology, College of Medicine and Public Health, Flinders University, Adelaide 5042, Australia.

We undertook a systematic review of swallowing biomechanics, as assessed using pharyngeal and esophageal manometry in healthy or dysphagic older individuals aged over 60 years of age, comparing findings to studies of younger participants. PRISMA-P methodology was used to identify, select, and evaluate eligible studies. Across studies, older participants had lower upper esophageal sphincter (UES) resting pressures and evidence of decreased UES relaxation when compared to younger groups. Read More

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http://dx.doi.org/10.3390/geriatrics3040067DOI Listing
October 2018

Oesophageal atresia.

Nat Rev Dis Primers 2019 Apr 18;5(1):26. Epub 2019 Apr 18.

Emma Children's Hospital, Amsterdam UMC, University of Amsterdam, Pediatric Gastroenterology and Nutrition, Amsterdam, The Netherlands.

Oesophageal atresia (EA) is a congenital abnormality of the oesophagus that is caused by incomplete embryonic compartmentalization of the foregut. EA commonly occurs with a tracheo-oesophageal fistula (TEF). Associated birth defects or anomalies, such as VACTERL association, trisomy 18 or 21 and CHARGE syndrome, occur in the majority of patients born with EA. Read More

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http://www.nature.com/articles/s41572-019-0077-0
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http://dx.doi.org/10.1038/s41572-019-0077-0DOI Listing
April 2019
1 Read

Hypercontractile esophageal motility disorder or functional esophageal symptoms and unrelated hypercontractility?

Neurogastroenterol Motil 2019 May;31(5):e13594

Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.

In this issue of the journal, Mion and coworkers describe 23 patients with dysphagia and/or thoracic pain and hypercontractile esophageal motility disorders who were either treated with botulinum toxin 100 U or underwent a sham procedure. The surprising outcome of the study was that both active botulinum toxin treatment and sham treatment resulted in a significant reduction in symptoms and manometric abnormalities after 3 months, with no difference between the two arms. One can interpret the lack of effect of botulinum toxin over placebo as indicative of the benign natural history of hypercontractile esophageal motility disorders or be convinced that many patients with hypercontractility on manometry actually have functional symptoms not related to the manometric findings, and thus, treatment of hypercontractility is not more effective than placebo. Read More

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http://dx.doi.org/10.1111/nmo.13594DOI Listing
May 2019
1 Read

Chronic daily opioid exposure is associated with dysphagia, esophageal outflow obstruction, and disordered peristalsis.

Neurogastroenterol Motil 2019 Apr 17:e13601. Epub 2019 Apr 17.

Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin.

Background: Opioid receptors are present in the esophagus, and chronic opioid therapy may be associated with esophageal dysfunction. Given the current opioid epidemic in the United States, the potential contribution of opioids to esophageal dysmotility is important from both public health and patient care perspectives. Therefore our aim is to investigate the potential contribution of opioids to dysphagia and the prevalence of major motor disorders in patients undergoing manometric evaluation. Read More

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http://dx.doi.org/10.1111/nmo.13601DOI Listing
April 2019
1 Read

Effective treatment improves the body composition of patients with esophageal motility disorders.

Dis Esophagus 2019 Apr 12. Epub 2019 Apr 12.

Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, and.

Although treatment for esophageal motility disorder improves dysphagia and increases body weight, the effect of the treatment on body composition is unclear. This study aimed to assess the change in body composition between before and after treatment, the preoperative predictors of muscle increase, and the association between muscle increase and quality of life. Sixty-one patients (achalasia, n = 55; spastic esophageal disorder n = 6) who underwent per-oral endoscopic myotomy were analyzed in a single-arm prospective observational study. Read More

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https://academic.oup.com/dote/advance-article/doi/10.1093/do
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http://dx.doi.org/10.1093/dote/doz022DOI Listing
April 2019
2 Reads

[Current Treatment of Achalasia 2019].

Zentralbl Chir 2019 Apr 12;144(2):163-170. Epub 2019 Apr 12.

Universitätsklinik für Chirurgie, Salzburger Landeskliniken, Salzburg, Österreich.

Treatment of primary idopathic achalasia, the most common of the rare oesophageal motility disorders, is currently changing. The therapeutic priciple of Heller's myotomy is increasingly accepted as standard. In 1913, the German surgeon Ernst Heller described the cardiomyotomy named after him, faciliating excellent symptom control. Read More

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http://dx.doi.org/10.1055/a-0863-4917DOI Listing
April 2019
1 Read

Botulinum toxin for the treatment of hypercontractile esophagus: Results of a double-blind randomized sham-controlled study.

Neurogastroenterol Motil 2019 May 11;31(5):e13587. Epub 2019 Apr 11.

CHU Bordeaux, Gastroenterology, Université de Bordeaux, Bordeaux, France.

Introduction: Botulinum toxin injection is known to be efficient to treat achalasia. We conducted a randomized trial in order to evaluate its efficacy to treat symptomatic hypercontractile esophageal disorders as characterized by esophageal high-resolution manometry.

Methods: Patients with significant dysphagia and/or thoracic pain related to an hypercontractile esophageal motility disorder as defined by the Chicago Classification were randomized to receive an injection of botulinum toxin (100 U in 10 points in the distal part of the esophageal wall) or a sham procedure. Read More

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http://dx.doi.org/10.1111/nmo.13587DOI Listing
May 2019
1 Read

Commentary on "Relationship Between Torticollis and Gastroesophageal Reflux Disorder in Infants".

Pediatr Phys Ther 2019 04;31(2):148

Cindy Miles & Associates Whitehall, Pennsylvania.

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http://dx.doi.org/10.1097/PEP.0000000000000604DOI Listing
April 2019
11 Reads

How I do it: Does this cost-effectiveness analysis convince me about screening for Barrett's esophagus?

Authors:
Uri Ladabaum

Gastrointest Endosc 2019 04;89(4):723-725

Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA.

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http://dx.doi.org/10.1016/j.gie.2018.12.016DOI Listing
April 2019
2 Reads

Advancements in the use of manometry and impedance testing for esophageal functional disorders.

Expert Rev Gastroenterol Hepatol 2019 May 21;13(5):425-435. Epub 2019 Mar 21.

b Gastrointestinal Unit, Department of Internal Medicine and Medical Specialties , University of Genoa , Genoa , Italy.

Introduction: The utilization of high-resolution manometry (HRM) has enhanced our understanding and assessment of esophageal motor disorders. Moreover, the combination of impedance technology with HRM (HRIM) has further improved our knowledge of esophageal physiology and the clinical evaluation of dysmotility, thanks to the addition of accurate measurement of bolus transit. Areas covered. Read More

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http://dx.doi.org/10.1080/17474124.2019.1595587DOI Listing
May 2019
1 Read

Characterization of Esophageal Motility in Infants with Congenital Diaphragmatic Hernia using High Resolution Manometry.

J Pediatr Gastroenterol Nutr 2019 Mar 5. Epub 2019 Mar 5.

Department of Neurosciences, Experimental Oto-Rhino-Laryngology, Deglutology, KU Leuven, Belgium.

Objectives: To characterize esophageal motility and esophago-gastric junction (EGJ) function in infants who underwent repair of an isolated congenital diaphragmatic hernia (iCDH).

Methods: High Resolution Manometry with impedance was used to investigate esophageal motility and EGJ function after diaphragmatic repair in 12 infants with iCDH (11 left-sided; 9 patch repair). They had esophageal motility studies during neonatal admission (n = 12), at 6 months (n = 10) and at 12 months of life (n = 7). Read More

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http://dx.doi.org/10.1097/MPG.0000000000002325DOI Listing
March 2019
1 Read

Do we need endoscopic ultrasonography for the workup of patients with esophageal motility disorder?

Clin Res Hepatol Gastroenterol 2019 Mar 14. Epub 2019 Mar 14.

Department of gastroenterology, Cochin Hospital, assistance publique-Hôpitaux de Paris, Paris, France; Paris Descartes University, Paris, France.

Introduction: Endoscopic ultrasonography (EUS) is advised in the workup of achalasia patients to rule out secondary achalasia or pseudoachalasia, and search for a typical esophageal wall thickening. The purpose of this study was to assess the clinical contribution of EUS findings in achalasia and other esophageal motility disorders (EMD).

Methods: We conducted a single center retrospective study at a tertiary referral centre. Read More

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http://dx.doi.org/10.1016/j.clinre.2019.02.005DOI Listing
March 2019
1 Read

[Esophageal achalasia].

Khirurgiia (Mosk) 2019(2):72-77

Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department, Moscow, Russia.

Prevalence, clinical manifestations and of modern classifications of achalasia are reviewed in the article. Diagnosis and treatment of this pathology were analyzed by using of 58 references. Read More

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http://www.mediasphera.ru/issues/khirurgiya-zhurnal-im-n-i-p
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http://dx.doi.org/10.17116/hirurgia201902172DOI Listing
January 2019
8 Reads

Achalasia Cardia Resulting in Bronchial Obstruction - A Case Series and Literature Review.

Korean J Gastroenterol 2019 Feb;73(2):105-108

Division of Gastroenterology and Hepatology, SBH Health System, Bronx, NY, USA.

Achalasia is a motility disorder of the esophagus that is characterized by loss of ganglionic neurons within the myenteric plexus of the lower esophageal sphincter (LES) resulting in failure of the LES to relax. Clinically this disorder presents with simultaneous dysphagia to solids and liquids, and if left untreated, leads to esophageal dilation, which can give rise to many adverse consequences. Extrinsic compression of respiratory structures is one such consequence, and rarely, cases of tracheal compression secondary to achalasia have been reported. Read More

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http://dx.doi.org/10.4166/kjg.2019.73.2.105DOI Listing
February 2019
2 Reads

Gastroesophageal Reflux Disease in the Neonatal Intensive Care Unit Infant: Who Needs to Be Treated and What Approach Is Beneficial?

Pediatr Clin North Am 2019 04 1;66(2):461-473. Epub 2019 Feb 1.

Innovative Research Program in Neonatal Feeding Disorders; The Neonatal and Infant Feeding Disorders Program, Nationwide Children's Hospital, Columbus, OH, USA; Division of Neonatology, Department of Pediatrics, Center for Perinatal Research, WB 5211, The Research Institute at Nationwide Children's Hospital, The Ohio State University College of Medicine, 575 Children's Cross Roads, Columbus, OH 43215, USA; Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Center for Perinatal Research, WB 5211, The Research Institute at Nationwide Children's Hospital, The Ohio State University College of Medicine, 575 Children's Cross Roads, Columbus, OH 43215, USA. Electronic address:

Gastroesophageal reflux (GER) and GER disease (GERD) pertaining to infants in the neonatal intensive care unit (NICU) are reviewed, based on research in this specific population. The developmental biology of the gastroesophageal junction, physiology of GER, and pathophysiology of GERD in this setting are summarized, and risk factors for GER and GERD identified. The epidemiology, economic burden, and controversies surrounding GERD in NICU infants are addressed, and an approach to GER and GERD in these patients formulated. Read More

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http://dx.doi.org/10.1016/j.pcl.2018.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400306PMC
April 2019
4 Reads

Nissen Fundoplication-Preserving Laparoscopic Sleeve Gastrectomy.

Am Surg 2019 Feb;85(2):173-176

Gastroesophageal reflux disease (GERD) is significantly more prevalent in obese patients. Nissen fundoplication alleviates symptoms in those refractory to dietary changes and optimal medical management. The need for concomitant treatment of GERD and obesity is becoming more prevalent. Read More

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February 2019
5 Reads

Multiple Rapid Swallows (MRS) Complements Single-Swallow (SS) Analysis for High-Resolution Esophageal Manometry (HREM).

Dig Dis Sci 2019 Feb 25. Epub 2019 Feb 25.

Gastroenterology Section, Department of Medicine, Lewis Katz School of Medicine at Temple University, 3401 North Broad Street, Philadelphia, PA, 19140, USA.

Background: Multiple rapid swallows (MRS) during HREM assess post-deglutitive inhibition, LES relaxation, and subsequent esophageal contraction.

Aims: (1) To determine the relationship between MRS and single-swallow (SS) responses and (2) to determine if MRS provides information for symptomatic patients.

Methods: Healthy volunteers (HVs) and patients underwent HREM [30-s landmark, ten 5-mL SS, MRS (5 consecutive 2-mL swallows every 2-3 s)] and were analyzed with ManoView software version 3 with CC version 3. Read More

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http://link.springer.com/10.1007/s10620-019-05545-2
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http://dx.doi.org/10.1007/s10620-019-05545-2DOI Listing
February 2019
7 Reads

FOOD INTAKE, NUTRITIONAL STATUS AND GASTROINTESTINAL SYMPTOMS IN CHILDREN WITH CEREBRAL PALSY.

Arq Gastroenterol 2018 Oct-Dec;55(4):352-357

Universidade Federal de São Paulo, Escola Paulista de Medicina, Disciplina de Gastroenterologia Pediátrica, São Paulo, SP, Brasil.

Background: Cerebral palsy may be associated with comorbidities such as undernutrition, impaired growth and gastrointestinal symptoms. Children with cerebral palsy exhibit eating problems due to the effect on the anatomical and functional structures involved in the eating function resulting in malnutrition.

Objective: The aim of this study was to investigate the association between food intake, nutritional status and gastrointestinal symptoms in children with cerebral palsy. Read More

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http://dx.doi.org/10.1590/S0004-2803.201800000-78DOI Listing
March 2019
2 Reads

Association between digestive symptoms and sleep disturbance: a cross-sectional community-based study.

BMC Gastroenterol 2019 Feb 19;19(1):34. Epub 2019 Feb 19.

Future Medicine Division, Korea Institute of Oriental Medicine, Daejeon, 1672, Republic of Korea.

Background: This study was conducted to analyze the association between digestive symptoms and sleep disturbance, and to determine if any digestive symptoms are related to sleep disturbance.

Methods: This was a cross-sectional study of 5792 subjects surveyed in a community-based cohort. Subjects provided information regarding the quality of sleep as assessed by the Pittsburgh Sleep Quality Index (PSQI), as well as digestive symptoms as assessed by the Gastrointestinal Symptom Rating Scale (GSRS). Read More

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http://dx.doi.org/10.1186/s12876-019-0945-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381712PMC
February 2019
6 Reads

The association between temporal measures of swallowing with penetration and aspiration in patients with dysphagia: A meta-analysis.

NeuroRehabilitation 2019 ;44(1):111-129

Swallowing Lab, University of Toronto, University Health Network, Canada.

Introduction: Temporal features of swallowing physiology vary with age in healthy normals and have the potential to impact swallow safety and efficiency in patients with dysphagia. We conducted a meta-analysis to assess the relation between temporal features of swallowing with penetration, aspiration and residue in adult patients with dysphagia regardless of etiology.

Methods: Operational definitions of relevant terms were defined a priori. Read More

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https://www.medra.org/servlet/aliasResolver?alias=iospress&a
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http://dx.doi.org/10.3233/NRE-182553DOI Listing
April 2019
9 Reads

The high frequency of esophageal disorders in Iranian patients with non-cardiac chest pain.

Gastroenterol Hepatol Bed Bench 2018 ;11(Suppl 1):S32-S38

Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Aim: The aim of this study was to evaluate the prevalence of gastrointestinal disorders in non-cardiac chest pain (NCCP) Iranian patients.

Background: Gastro-esophageal reflux disease (GERD) is the most common cause of NCCP, which accounts for about one third of cases.

Methods: This was a descriptive study on consecutive NCCP patients who referred to the gastroenterology clinic at the Taleghani Hospital, Tehran, Iran from 2015 to 2017. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347990PMC
January 2018
11 Reads

Contribution of ghrelin to functional gastrointestinal disorders' pathogenesis.

World J Gastroenterol 2019 Feb;25(5):539-551

Department of Basic Medical Science, Laboratory of Biology, School of Medicine, University of Athens, Athens 11527, Greece.

Functional gastrointestinal disorders (FGID) are heterogeneous disorders with a variety of clinical manifestations, primarily defined by signs and symptoms rather than a definite underlying cause. Their pathophysiology remains obscure and, although it is expected to differ according to the specific FGID, disruptions in the brain-gut axis are now thought to be a common denominator in their pathogenesis. The hormone ghrelin is an important component of this axis, exerting a wide repertoire of physiological actions, including regulation of gastrointestinal motility and protection of mucosal tissue. Read More

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http://dx.doi.org/10.3748/wjg.v25.i5.539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371003PMC
February 2019
8 Reads

The laparoscopic approach for epiphrenic diverticula with achalasia.

Ann R Coll Surg Engl 2019 Apr 18;101(4):256-260. Epub 2019 Feb 18.

Zen Hospital , Mumbai , India.

Introduction: Epiphrenic diverticulum (ED) is an uncommon disease that is invariably associated with an underlying oesophageal motility disorder such as achalasia. Management of ED should always be accompanied by treatment of the underlying motility disorder to prevent recurrence of symptoms. Traditionally, ED were approached via a left thoracotomy but as laparoscopy offers better access to the distal oesophagus, its use is becoming more widespread. Read More

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http://dx.doi.org/10.1308/rcsann.2019.0007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432961PMC
April 2019
4 Reads

Impact of Peppermint Therapy on Dysphagia and Non-cardiac Chest Pain: A Pilot Study.

Dig Dis Sci 2019 Feb 15. Epub 2019 Feb 15.

Department of Medicine, Division of Gastroenterology and Hepatology, Medical University of South Carolina, 30 Courtenay Drive, Suite 249, MSC 702, Charleston, SC, 29425-2900, USA.

Background: Due to its smooth muscle relaxing properties, peppermint oil (PO) may relieve dysphagia and chest pain due to esophageal motility disorders.

Aim: To explore the impact of PO on dysphagia and/or chest pain in patients referred for motility testing.

Methods: Patients initiated on PO for dysphagia and/or chest pain from 2013 to 2016 were identified. Read More

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http://link.springer.com/10.1007/s10620-019-05523-8
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http://dx.doi.org/10.1007/s10620-019-05523-8DOI Listing
February 2019
22 Reads
2.550 Impact Factor

Reflux Symptoms in Gastroparesis: Correlation With Gastroparesis Symptoms, Gastric Emptying, and Esophageal Function Testing.

J Clin Gastroenterol 2019 Feb 12. Epub 2019 Feb 12.

Section of Gastroenterology, Department of Medicine, Temple University School of Medicine, Philadelphia, PA.

Goal: The goal of this study was to determine the relationship of reflux with gastroparesis (Gp), looking both at symptoms and objective testing.

Background: Gp patients often experience gastroesophageal reflux symptoms. How the severity of reflux correlates with the severity of Gp is not known. Read More

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http://dx.doi.org/10.1097/MCG.0000000000001190DOI Listing
February 2019
2 Reads

Persistent mental and physical health impact of exposure to the September 11, 2001 World Trade Center terrorist attacks.

Environ Health 2019 02 12;18(1):12. Epub 2019 Feb 12.

World Trade Center Health Registry, New York City Department of Health and Mental Hygiene, New York, NY, USA.

Background: Asthma, gastroesophageal reflux disease (GERD), posttraumatic stress disorder (PTSD) and depression have each been linked to exposure to the September 11, 2001 World Trade Center (WTC) terrorist attacks (9/11). We described the prevalence and patterns of these conditions and associated health-related quality of life (HRQOL) fifteen years after the attacks.

Methods: We studied 36,897 participants in the WTC Health Registry, a cohort of exposed rescue/recovery workers and community members, who completed baseline (2003-2004) and follow-up (2015-16) questionnaires. Read More

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http://dx.doi.org/10.1186/s12940-019-0449-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373081PMC
February 2019
9 Reads

Eosinophilic esophagitis and achalasia - just a coincidence?

Z Gastroenterol 2019 Feb 12;57(2):151-155. Epub 2019 Feb 12.

Medizinische Klinik II, HELIOS Klinikum Krefeld, Germany.

Background:  Eosinophilic esophagitis (EoE) is detected frequently in dysphagia and noncardiac chest pain. Management of patients with EoE may be complicated because EoE is associated frequently with esophageal motility disorders. We present the rare case of esophageal achalasia (EA) associated with eosinophilic infiltration and a literature review. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0808-5043
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http://dx.doi.org/10.1055/a-0808-5043DOI Listing
February 2019
8 Reads

Redo Surgery after Failure of Antireflux Surgery.

Am Surg 2018 Nov;84(11):1819-1824

Surgery for refractory gastroesophageal reflux disease (GERD) has a satisfactory outcome for most patients; however, sometimes redo surgery is required. The Outcome and morbidity of a redo are suggested to be less successful than those of primary surgery. The aim of this study was to describe our experience, long-term results, and complications in redo surgery. Read More

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November 2018
3 Reads

The Use of Rigiflex Pneumatic Balloon Dilator during Laparoscopic Heller's Myotomy in Patients with Achalasia: A Novel Technical Method and Its Surgical Outcomes.

Am Surg 2018 Nov;84(11):1796-1800

Pneumatic balloon dilatation (BD) and laparoscopic Heller's myotomy (LHM) are usually preferred treatment options for relieving dysphagia symptoms in achalasia. The aim of the present study was to describe a new technical method for a safe and effective LHM. Endoscopic BD tube (Rigiflex 30-mm pneumatic balloon) is simultaneously insufflated and desufflated in the esophagus during LHM to assess myotomy in 50 consecutive patients. Read More

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November 2018
2 Reads

Comparative Analysis of Laparoscopic Fundoplication and Magnetic Sphincter Augmentation for the Treatment of Medically Refractory GERD.

Am Surg 2018 Nov;84(11):1762-1767

We have recently introduced laparoscopic magnetic sphincter augmentation (MSA) combined with hiatal hernia repair for treatment of patients with medically refractory gastroesophageal reflux disease (GERD). MSA is a novel surgical approach to the treatment of severe GERD, in which magnetic beads are secured around the lower esophageal sphincter, augmenting the lower esophageal sphincter function as an anti-reflux barrier. We hypothesize that patients undergoing MSA will achieve GERD relief, equal to that obtained after laparoscopic Nissen fundoplication. Read More

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November 2018
8 Reads

Plasma levels of TNF-α, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23 in achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD).

BMC Gastroenterol 2019 Feb 11;19(1):28. Epub 2019 Feb 11.

University of South Florida, Division of Gastroenterology, Florida, USA.

An elevation of serum inflammatory biomarkers in achalasia patients compared with controls recently was demonstrated. It has not been determined whether the elevation of inflammatory cytokines is unique to achalasia or occurs with other diseases involving the esophagus. The primary aim of our study was to compare the differences in plasma immunological profiles (TNF- α receptor, IL-6, IFN-γ, IL-12, IL-17, IL-22, and IL-23) of patients with achalasia, eosinophilic esophagitis (EoE), and gastroesophageal reflux disease (GERD). Read More

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http://dx.doi.org/10.1186/s12876-019-0937-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371504PMC
February 2019
3 Reads

Heller Myotomy for Epiphrenic Diverticula Compared to Nondiverticula Esophageal Motility Disorders, A Single Institution Experience and Appraisal of Patient Characteristics, High-Resolution Manometry and Outcomes.

Dig Surg 2019 Feb 5:1-9. Epub 2019 Feb 5.

Division of General Surgery, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA,

Purpose: The purpose of this study was to compare demographics, symptoms, prior interventions, operation, and outcomes of patients who underwent Heller myotomy for esophageal motility disorders and epiphrenic diverticulectomy with Heller myotomy.

Methods: We identified all patients who underwent Heller myotomy for esophageal motility disorders with and without esophageal diverticulectomy over an 80-month period. Primary data points included patient demographics, presenting symptoms, prior intervention, high-resolution manometry, surgery performed with rate of laparoscopic, conversion to open, and open procedures; postoperative complications, and symptom resolution. Read More

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http://dx.doi.org/10.1159/000496804DOI Listing
February 2019
2 Reads

New Developments in Esophageal Motility Testing.

Curr Treat Options Gastroenterol 2019 Mar;17(1):76-88

University of Colorado Reflux & Esophageal Diseases Center, Division of Gastroenterology & Hepatology, Department of Medicine, University of Colorado, Anschutz Medical Campus, Academic Office 1 Room 7605, 12631 E. 17th Ave, Aurora, CO, 80045, USA.

Purpose Of Review: The purpose of this review is to present the latest developments in esophageal motility testing and summarize the current paradigm of esophageal motility disorders.

Recent Findings: While high-resolution esophageal pressure topography interpreted according to the Chicago Classification represents the gold standard to evaluate esophageal motility, recent studies highlight the additional value of novel manometric applications. Novel applications include provocative measures to assess for obstructive physiology at the esophagogastric junction (EGJ), esophageal peristaltic reserve, and rumination and supragastric belching disorders. Read More

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http://link.springer.com/10.1007/s11938-019-00218-5
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http://dx.doi.org/10.1007/s11938-019-00218-5DOI Listing
March 2019
22 Reads

Laryngopharyngeal reflux concept: what is known and what should we focus on?

Braz J Otorhinolaryngol 2019 Mar - Apr;85(2):133-135. Epub 2019 Jan 19.

Acıbadem Bakırköy Hospital, Department of Otorhinolaryngology-Head and Neck Surgery, Istanbul, Turkey.

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http://dx.doi.org/10.1016/j.bjorl.2019.01.001DOI Listing

Upright Integrated Relaxation Pressure Facilitates Characterization of Esophagogastric Junction Outflow Obstruction.

Clin Gastroenterol Hepatol 2019 Jan 29. Epub 2019 Jan 29.

Department of Medicine, Division of Gastroenterology and Hepatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

Background & Aims: Under the Chicago Classification of esophageal motility disorders, esophagogastric junction outflow obstruction (EGJOO) includes a varied clinical spectrum that results in diagnostic and management difficulties. We aimed to demonstrate that including upright swallows during high-resolution manometry (HRM) helps identify patients with clinically significant EGJOO.

Methods: We performed a retrospective study of consecutive patients diagnosed with EGJOO on HRM from January 2015 through July 2017. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15423565193007
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http://dx.doi.org/10.1016/j.cgh.2019.01.024DOI Listing
January 2019
11 Reads

On respiratory manifestations of gastroesophageal reflux disease.

Ter Arkh 2018 Aug;90(8):131-136

Acad. I.P. Pavlov Ryazan State Medical University, Ministry of Health of Russia, Ryazan, Russia.

One of the manifestations of gastroesophageal reflux disease (GERD) is extraesophageal symptoms, in particular, from the upper and lower respiratory tract. Gastroesophageal reflux is capable of both causing respiratory symptoms independently and aggravating the course of already existing diseases of the respiratory system. The article presents available in the literature current information on the pathogenesis of GERD respiratory symptoms, their clinical course, considerations of diagnosis and treatment. Read More

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http://dx.doi.org/https://doi.org/10.26442/terarkh2018908131-136DOI Listing
August 2018
8 Reads

Problems of nociception in gastroesophageal reflux disease: diagnostics and treatment of irritated oesophagus.

Ter Arkh 2018 Aug;90(8):118-124

SM-clinic, Saint-Petersburg, Russia.

The following factors of gastroesophageal reflux disease (GERD) pathogenesis are addressed in the abstract: activation of nociceptors, hyperexpression of pro-inflammatory cytokines and increase of functional activity of immune competent cells. The current classification of GERD is given which is based on identification of 4 phenotypes of the disease according to diagnostic criteria and prognosis of treatment effectiveness. Importance of pH-impedance monitoring in GERD diagnostics is demonstrated based on its primary significance for identification of reflux nature and determination of relationship between GERD symptoms and reflux. Read More

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http://ter-arkhiv.ru/en/archive/2018/vol-90-8-2018/problems-
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http://dx.doi.org/10.26442/terarkh2018908118-124DOI Listing
August 2018
6 Reads

Modern achievements in the diagnosis and treatment of the refractory gastroesophageal reflux disease.

Ter Arkh 2018 Aug;90(8):4-12

I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.

Purpose of the review to present up-to-date data on the causes, methods of diagnosis and treatment of the refractory form of gastroesophageal reflux disease (GERD). Refractory GERD is the preservation of typical symptoms of the disease and/or incomplete healing of the esophageal mucosa against the background of taking a standard dose of proton pump inhibitors (PPI) once a day for 8 weeks. The reasons for the lack of response to the treatment are divided into related to the patient, related to therapy, and not related to GERD. Read More

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http://ter-arkhiv.ru/en/archive/2018/vol-90-8-2018/modern-ac
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http://dx.doi.org/10.26442/terarkh20189084-12DOI Listing
August 2018
9 Reads

High resolution manometry and new classification of esophageal motility disorders.

Ter Arkh 2018 May;90(5):93-100

Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia.

Aim: To present application of Chicago classification criteria of esophageal motility disorders defined in high resolution manometry in clinical practice.

Materials And Methods: High-resolution manometry is the most exact hi-tech diagnostic method for esophageal motor function disorders according to Chicago classification v3.0. Read More

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http://dx.doi.org/10.26442/terarkh201890593-100DOI Listing
May 2018
15 Reads

Esophagogastric junction outflow obstruction: Where are we now in diagnosis and management?

World J Gastroenterol 2019 Jan;25(4):411-417

Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, GA 30322, United States.

Esophagogastric junction outflow obstruction (EGJOO) is a major motility disorder based on the Chicago Classification of esophageal motility disorders. This entity involves a heterogenous group of underlying etiologies. The diagnosis is reached by performing high-resolution manometry. Read More

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http://dx.doi.org/10.3748/wjg.v25.i4.411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350167PMC
January 2019
2 Reads

Do patients with gastroesophageal reflux disease and somatoform tendencies benefit from antireflux surgery?

World J Gastroenterol 2019 Jan;25(3):388-397

NAFKAM, Department of Community Medicine, UiT, The Arctic University of Norway, Tromsoe, N-9037, Norway.

Background: The clinical presentation of gastroesophageal reflux disease (GERD) shows a large symptom variation also in different intensities among patients. As several studies have shown, there is a large overlap in the symptomatic spectrum between proven GERD and other disorders such as dyspepsia, functional heartburn and/or somatoform disorders.

Aim: To prospectively evaluate the GERD patients with and without somatoform disorders before and after laparoscopic antireflux surgery. Read More

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http://dx.doi.org/10.3748/wjg.v25.i3.388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343096PMC
January 2019
7 Reads

Advances in the Diagnosis and Treatment of GERD: New Tricks for an Old Disease.

Curr Treat Options Gastroenterol 2019 Mar;17(1):1-17

Division of Gastroenterology, Hepatology, and Nutrition, Center for Swallowing and Esophageal Disorders, Digestive Disease Center, Vanderbilt University Medical Center, 1660 TVC, Nashville, TN, 37232-5280, USA.

Purpose Of Review: Gastroesophageal reflux disease (GERD) is a common diagnosis encountered by both primary care providers and specialists, but despite its prevalence, there are limitations in the current diagnostic tests for GERD. Once an accurate diagnosis is made, treatment options can be offered, and this field continues to burgeon with options. In this review, we seek to review the recent advances in GERD diagnostics and subsequent treatment options. Read More

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http://dx.doi.org/10.1007/s11938-019-00213-wDOI Listing
March 2019
28 Reads

Melatonin for the treatment of gastroesophageal reflux disease; protocol for a systematic review and meta-analysis.

Medicine (Baltimore) 2019 Jan;98(4):e14241

Background: Melatonin generated in the gastrointestinal tract has mucosal protective effect with inhibiting gastric acid secretion, while increasing gastrin release, which in turn stimulates the contractility of lower esophageal sphincter. Gastroesophageal reflux disease (GERD) is also known to have association with sleep disturbance. However, melatonin or melatonin receptor agonist has not been included in the treatment of GERD. Read More

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http://Insights.ovid.com/crossref?an=00005792-201901250-0006
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http://dx.doi.org/10.1097/MD.0000000000014241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358381PMC
January 2019
8 Reads
5.723 Impact Factor

Association between tea consumption and gastroesophageal reflux disease: A meta-analysis.

Medicine (Baltimore) 2019 Jan;98(4):e14173

Department of Proctology, Jining No.1 People's Hospital, Jining, Shandong, China.

Background: Gastroesophageal reflux disease (GERD) is one of the most common digestive system diseases, which is associated with lifestyle and dietary factors. The main mechanism involved in GERD is affected by demographics, lifestyles, and dietary factors. Tea consumption is reported to be associated with GERD, especially in Asian population. Read More

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http://Insights.ovid.com/crossref?an=00005792-201901250-0003
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http://dx.doi.org/10.1097/MD.0000000000014173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358326PMC
January 2019
7 Reads

Megaesophagus in a Patient with Achalasia.

GE Port J Gastroenterol 2018 Dec 13;26(1):75-77. Epub 2018 Mar 13.

Gastroenterology Department, Amato Lusitano Hospital, Castelo Branco, Portugal.

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http://dx.doi.org/10.1159/000487276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341370PMC
December 2018
1 Read

pH Scores in Hiatal Repair with Transoral Incisionless Fundoplication.

JSLS 2019 Jan-Mar;23(1)

Department of Surgery, San Angelo Community Medical Center, San Angelo, TX 76904, USA.

Background And Objectives: Transoral incisionless fundoplication is an alternative to traditional laparoscopic fundoplications. Recently, hiatal hernia repair combined with transoral incisionless fundoplication has become an accepted modification of the original procedure; however, outcomes information, particularly objective pH monitoring, has been sparse. We retrospectively review the subjective and objective outcomes of transoral incisionless fundoplication combined with hiatal hernia repair. Read More

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333564/
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http://dx.doi.org/10.4293/JSLS.2018.00087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333564PMC
March 2019
11 Reads

Superior mesenteric artery syndrome coexists with Nutcracker syndrome in a female: a case report.

BMC Gastroenterol 2019 Jan 23;19(1):15. Epub 2019 Jan 23.

Department of Gastroenterology, The First Affiliated Hospital, Jinan University, Guangzhou, 510630, People's Republic of China.

Background: Superior mesenteric artery (SMA) syndrome, also known as Wilkie's syndrome or Benign duodenal stasis, is a rare benign disease. It could threaten the life if the manifestation is severe and the treatment is inappropriate. In the patients with SMA syndrome, the third portion (transverse part) of the duodenum is compressed externally between the SMA and abdominal aorta (AA) leading to duodenal stasis and gastrointestinal obstruction. Read More

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https://bmcgastroenterol.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12876-019-0932-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343343PMC
January 2019
10 Reads

Reimbursement for endoscopic innovations: the final hurdle.

Gastrointest Endosc 2019 02;89(2):274-276

Predictive Health, University of Arizona College of Medicine - Phoenix, Phoenix, Arizona, USA.

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http://dx.doi.org/10.1016/j.gie.2018.09.022DOI Listing
February 2019
2 Reads
5.369 Impact Factor

Is EndoFLIP Useful for Predicting Clinical Outcomes after Peroral Endoscopic Myotomy in Patients with Achalasia?

Authors:
Gwang Ha Kim

Gut Liver 2019 01;13(1):3-4

Department of Internal Medicine, Pusan National University School of Medicine, and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.

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http://dx.doi.org/10.5009/gnl18443DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347008PMC
January 2019
3 Reads