36,450 results match your criteria Esophageal Motility Disorders

[Esophageal achalasia: possible pathogenic concepts from the perspective of modern notions].

Khirurgiia (Mosk) 2021 (5):104-108

Spasokukotskiy Clinical Hospital, Moscow, Russia.

Esophageal achalasia is an esophageal motility disease characterized by impaired relaxation of lower esophageal sphincter (LES) and severe clinical symptoms. The main etiological factors and other essential aspects of pathogenesis and progression of this disorder are actively studied. To date, the question of significance of etiological factors is experimental and requires further study. Read More

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Impact of patient position on esophageal motility disorders using high-resolution esophageal manometry with impedance (HREMI): supine versus upright swallows.

Esophagus 2021 May 11. Epub 2021 May 11.

Gastroenterology Section; Department of Medicine, Lewis Katz School of Medicine At Temple University, 3401 N Broad St, Philadelphia, PA, 19140, USA.

Background: High-resolution esophageal manometry with impedance (HREMI) performed with supine patient positioning is used to evaluate patients for esophageal dysmotility. However, most patients experience symptoms related to esophageal dysmotility when eating or drinking upright. The aims of this study are to: (1) compare HREMI metrics in supine versus upright position; and (2) determine if upright position alters motility characterization of patients. Read More

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Preoperative physiological esophageal assessment for anti-reflux surgery: A guide for surgeons on high-resolution manometry and pH testing.

World J Gastroenterol 2021 Apr;27(16):1751-1769

Department of Gastroenterology, Albany Medical Center, Schenectady, NY 12309, United States.

Gastroesophageal reflux disease (GERD) is one of the most commonly encountered digestive diseases in the world, with the prevalence continuing to increase. Many patients are successfully treated with lifestyle modifications and proton pump inhibitor therapy, but a subset of patients require more aggressive intervention for control of their symptoms. Surgical treatment with fundoplication is a viable option for patients with GERD, as it attempts to improve the integrity of the lower esophageal sphincter (LES). Read More

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Georgian Med News 2021 Mar(312):67-71

State Higher Educational Institution «Uzhhorod National University», Medical Faculty, Ukraine.

Of particular interest is the study of the peculiarities of clinical findings and diagnostics of gastroesophageal reflux disease (GERD) in patients with diabetes mellitus (DM). The aim of the research - to study the dynamics of cholecystokinin (CCK) level on the background of complex therapy using the ursodeoxycholic acid (UDCA) drug in patients with GERD with type 2 DM. 68 patients with combination of type 2 DM and GERD were examined. Read More

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Georgian Med News 2021 Mar(312):23-26

2Ivane Javakhishvili Tbilisi State University, Georgia.

The purpose was to study the features and results of redo laparoscopic antireflux surgery. For the period from 2008 to 2019, in Odessa Regional Hospital laparoscopic antireflux operations were performed in 1164 patients. 57 patients underwent laparoscopic reoperation during the study period based on the following indications: recurrence of hiatal hernia (n=37), recurrent reflux (n=4), dysphagia (n=8), severe pain (n=5), esophageal stricture (n=3). Read More

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Manometric changes of the esophagus in morbidly obese patients.

Exp Ther Med 2021 Jun 14;21(6):604. Epub 2021 Apr 14.

5th Clinical Department, Gastroenterology and Internal Medicine Discipline, 'Carol Davila' University of Medicine and Pharmacy, 050474 Bucharest, Romania.

This prospective study aimed to determine the manometric pattern and the prevalence of esophageal dysmotility in 79 morbidly obese patients selected for laparoscopic sleeve gastrectomy. After clinical evaluation and upper gastrointestinal endoscopy, high-resolution esophageal manometry was performed. The esophageal peristalsis, lower esophageal sphincter (LES) basal pressure, and LES relaxation were evaluated. Read More

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Achalasia is associated with a higher incidence of depression in outpatients in Germany.

PLoS One 2021 30;16(4):e0250503. Epub 2021 Apr 30.

Clinic for Gastroenterology, Hepatology and Infectious Diseases, University Hospital Düsseldorf, Medical Faculty of Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Background And Aim: Achalasia represents a chronic motility disorder of the esophagus featuring an impaired lower esophageal sphincter relaxation and loss of esophageal peristalsis. By causing dysphagia, regurgitation, aspiration and chest pain, achalasia might tremendously affect life quality of patients. However, the impact of achalasia on the development of mood disorders including depression has largely remained unclear. Read More

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Arq Gastroenterol 2021 Jan-Mar;58(1):5-9

Universidade de São Paulo, Faculdade de Medicina, Departamento de Gastroenterologia, São Paulo, SP, Brasil.

Background: Heartburn and acid regurgitation are typical symptoms usually associated with gastroesophageal reflux disease (GERD). GERD is one of the gastrointestinal diagnosis with higher prevalence worldwide, significantly impairing patients' quality of life.

Objective: The objective of this study was to analyze the impact of GERD-related symptoms in the Brazilian urban population. Read More

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Pharmacological Management of Gastro-Esophageal Reflux Disease: An Update of the State-of-the-Art.

Drug Des Devel Ther 2021 19;15:1609-1621. Epub 2021 Apr 19.

Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.

Gastro-esophageal reflux disease (GERD) is a highly prevalent, chronic disorder, whose knowledge remains limited and the management of these patients changes continuously. This review provides a summary of the most recent advancements in the pathogenesis of this disease and the new drugs introduced into the market to overcome some of the unmet needs of traditional therapies. Nowadays, the most fruitful diagnostic examinations are 24-hour impedance-pH monitoring, which allows us to separate true NERD from esophageal functional disorders and high-resolution manometry, which helps to exclude the existence of motility disorders sharing the same symptoms of GERD. Read More

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[Cough from an allergological as well as from the ENT aspect].

Ther Umsch 2021 ;78(4):165-170

Poliklinik für Allergologie und klinische Immunologie, Universitätsklinik für Pneumologie, Inselspital Bern.

Cough from an allergological as well as from the ENT aspect Cough is a common problem in the allergological, but less so in the rhinological consultation. The differential diagnostic spectrum for cough is extensive and may range from rhinitis and asthma to eosinophilic esophagitis and rarer diseases. In the case of chronic cough (> 2 months), the four most frequent causes must be sought, or be excluded (upper airway cough syndrome, asthma [cough-variant-asthma], non-asthmatic eosinophilic bronchitis, gastroesophageal reflux disease). Read More

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[Cough from the perspective of a gastroenterologist].

Ther Umsch 2021 ;78(4):171-179

Abteilung für Gastroenterologie, Universitätsklinik für Viszerale Chirurgie und Medizin, Inselspital, Universitätsspital Bern.

Cough from the perspective of a gastroenterologist Chronic cough can have numerous origins. The work-up of these conditions should always include a multidisciplinary approach to exclude other causes first (cardial, pulmonary, structural changes of pharynx and larynx, allergies, malignancy) before thinking of an upper GI pathology. Cough as an extra-esophageal manifestation of gastroesophageal reflux disease (GERD) is the most common gastroenterological condition. Read More

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[Cough - an Interdisciplinary Condition: The Pneumologist's Perspective].

Ther Umsch 2021 ;78(4):187-194

Universitätsklinik für Pneumologie, Inselspital, Universitätsspital Bern.

Cough - an Interdisciplinary Condition: The Pneumologist's Perspective Cough is one of the most frequent reasons for a medical consultation. Patients mostly suffer from acute cough (< 2 weeks duration) and subacute cough (2 - 8 weeks) during consultation at primary care. Chronic cough (> 8 weeks) is mostly cared for by specialists. Read More

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Endoscopy 2021 05 22;53(5):557. Epub 2021 Apr 22.

Gastrointestinal Endoscopy Unit, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.

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Author commentary on Olivier Ragi et al.


Endoscopy 2021 05 22;53(5):v20. Epub 2021 Apr 22.

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Impact of bariatric surgery on gastroesophageal reflux disease and esophageal motility.

Anh D Nguyen

Curr Opin Gastroenterol 2021 Apr 14. Epub 2021 Apr 14.

Division of Gastroenterology and Center for Esophageal Diseases, Baylor University Medical Center, and the Center for Esophageal Research, Baylor Scott & White Research Institute, Dallas, Texas, USA.

Purpose Of Review: Obesity is rapidly increasing in prevalence, and bariatric surgery has become a popular treatment option that can improve all-cause mortality in obese individuals. Gastroesophageal reflux disease (GERD) and esophageal motility disorders are common in the obese population, and the effects of bariatric surgery on these conditions differ depending on the type of bariatric surgery performed.

Recent Findings: Laparoscopic adjustable gastric banding has declined in popularity due to its contributions to worsening GERD symptoms and the development of esophageal dysmotility. Read More

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Per Oral Endoscopic Myotomy for the Management of Achalasia in a Patient with Prior Lap Band, Sleeve Gastrectomy, and Roux-en-Y Gastric Bypass.

Obes Surg 2021 Jun 15;31(6):2843-2844. Epub 2021 Apr 15.

Service de Chirurgie Digestive, Clinique Geoffroy Saint Hilaire, Ramsay Santé, Paris, France.

Introduction: Achalasia after bariatric surgery is a rare pathological entity. Nonetheless, several cases have been described in literature. Per oral endoscopic myotomy has recently emerged as the preferred approach for the management of esophageal motility disorders. Read More

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Recurrence of dysphagia post-myotomy: etiologies and management.

Rev Col Bras Cir 2021 9;48:e20202973. Epub 2021 Apr 9.

- Centro Universitário Lusíada, Departamento de Medicina Baseada em Evidências - Santos - SP - Brasil.

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[Alternative Surgical Anti-Reflux Procedures].

Zentralbl Chir 2021 Apr 13;146(2):210-214. Epub 2021 Apr 13.

Universitätsklinik für Viszeralchirurgie, Medizinische Universität Wien, Österreich.

Patient satisfaction when treated with acid-suppressing medication for chronic GERD disease is less than 70%. Surgical standardisation, centralisation, improved awareness of patient selection and new surgical methods have stimulated interest in surgical reflux therapy in recent years. Magnetic sphincter augmentation (MSA) seems to be a safe alternative to laparoscopic fundoplication, with reported complication rates of 0. Read More

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[Mesh Implantation in Anti-Reflux and Hiatal Hernia Surgery - Contra Statement].

Zentralbl Chir 2021 Apr 13;146(2):200-203. Epub 2021 Apr 13.

Klinik für Chirurgie, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Deutschland.

In the surgical treatment of gastroesophageal reflux disease and of hiatal hernias, the high rate of recurrence of hiatal hernias is a central problem. Against this background, various, primarily alloplastic, meshes are used to augment suture closure on the esophageal hiatus. Very different results have been reported in the past and the use of meshes in hiatus reconstruction is controversial. Read More

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[Update on Endoscopic Therapies for the Treatment of GERD: GERDX, MUSE, EsophyX].

Andreas Tschoner

Zentralbl Chir 2021 Apr 13;146(2):188-193. Epub 2021 Apr 13.

Abteilung für Allgemein-, Viszeral-, Gefäß- und Thoraxchirurgie, Ordensklinikum Linz, Barmherzige Schwestern Hospital, Österreich.

Gastroesophageal reflux disease (GERD) has been a problem for patients throughout in recent decades worldwide and its prevalence is increasing. Until 20 years ago, the established treatments were the proton pump inhibitors (PPI) and varieties of laparoscopic fundoplication (LF). Increasing experience with endoscopy and knowledge of the oesophagogastric junction (EGJ) has led to new options in the treatment of GERD. Read More

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Review of Gastroesophageal Reflux Disease.

JAMA 2021 04;325(14):1472

Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston.

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Review of Gastroesophageal Reflux Disease-Reply.

JAMA 2021 04;325(14):1472-1473

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

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Comparison of nutrition and quality of life of esophagogastrostomy and the double-tract reconstruction after laparoscopic proximal gastrectomy.

Medicine (Baltimore) 2021 Apr;100(15):e25453

Center for Gastric Cancer, National Cancer Center, Goyang.

Abstract: This study aims to compare the nutritional outcomes and quality of life between patients who underwent esophagogastrostomy (EG) and those who underwent the double-tract reconstruction (DTR) after laparoscopic proximal gastrectomy for early gastric cancer.We retrospectively reviewed the prospectively established database of 45 patients who underwent EG with anti-reflux procedure and 58 patients who underwent the DTR after laparoscopic proximal gastrectomy between December 2013 and June 2017. Then, we compared the baseline characteristics, clinical outcomes, postoperative nutritional parameters, and quality of life (QOL) using European Organization for Research and Treatment of Cancer (EORTC) QLQ STO-22 between the EG and DTR groups. Read More

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[Characteristics of esophageal motility and clinical presentation in gastroesophageal reflux disease patients of different age groups].

Zhonghua Yi Xue Za Zhi 2021 Apr;101(14):1015-1019

Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China;Academy of Chinese Medical Sciences, Beijing 100102, China.

To explore the characteristics of esophageal motility and clinical presentation in gastroesophageal reflux disease (GERD) patients of different age groups. This was a case-control study. Confirmed GERD patients in the Department of Gastroenterology of Peking Union Medical College Hospital from January 2015 to September 2018 were enrolled and divided into two groups: elderly group (≥60 years old) and young and middle-aged group (<60 years old). Read More

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Potential of different fluoride gels to prevent erosive tooth wear caused by gastroesophageal reflux.

BMC Oral Health 2021 04 9;21(1):183. Epub 2021 Apr 9.

Clinic of Conservative and Preventive Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032, Zurich, Switzerland.

Background: This in-vitro-study aimed to evaluate the potential of different fluoride gels to prevent gastroesophageal reflux induced erosive tooth wear.

Methods: Surface baseline profiles of a total of 50 bovine enamel specimens [randomly assigned to five groups (G1-5)] were recorded. All specimens were positioned in a custom made artificial oral cavity and perfused with artificial saliva (0. Read More

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Effect of Food and Dosing Regimen on Safety and Efficacy of Proton Pump Inhibitors Therapy-A Literature Review.

Int J Environ Res Public Health 2021 03 29;18(7). Epub 2021 Mar 29.

Department of Food Chemistry and Nutrition, Faculty of Pharmacy, Jagiellonian University Medical College, 9 Medyczna Str, 30-688 Kraków, Poland.

Proton pump inhibitors (PPIs) are the first-choice drugs used to prevent and treat acid-related diseases. However, a lack of satisfactory response to the standard PPI dose ("PPI failure") is often reported, especially in patients with gastroesophageal reflux disease. Poor compliance seems to be one of the main causes of PPI failure; hence, it is crucial to gain knowledge on how to properly administer PPIs. Read More

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A Deep Learning Model for Classification of Endoscopic Gastroesophageal Reflux Disease.

Int J Environ Res Public Health 2021 03 2;18(5). Epub 2021 Mar 2.

Department of Medical Informatics, Chung Shan Medical University, Taichung 402, Taiwan.

Gastroesophageal reflux disease (GERD) is a common disease with high prevalence, and its endoscopic severity can be evaluated using the Los Angeles classification (LA grade). This paper proposes a deep learning model (i.e. Read More

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Electrogastrography Abnormalities in Pediatric Gastroduodenal Disorders: A Systematic Review and Meta-Analysis.

J Pediatr Gastroenterol Nutr 2021 Mar 31. Epub 2021 Mar 31.

Department of Surgery, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand Department of Medicine, University of Calgary, Calgary, Canada Suzi & Scott Lustgarten, Pediatric Motility Center, The Children's Hospital of Philadelphia, Philadelphia, United States Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States Auckland Bioengineering Institute, The University of Auckland, Auckland, New Zealand.

Objectives: Electrogastrography (EGG) is a non-invasive method of measuring gastric electrophysiology. Abnormal gastric electrophysiology is thought to contribute to disease pathophysiology in patients with gastroduodenal symptoms, but this has not been comprehensively quantified in pediatric populations. This study aimed to quantify the abnormalities in gastric electrophysiology on EGG in neonatal and pediatric patients. Read More

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[An epidemiological survey of laryngopharyngeal refux disease in otorhinolaryngology head and neck surgery clinics in Chongqing area].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2021 Apr;35(4):351-354;359

Department of Otolaryngology Head and Neck Surgery,Affiliated Hospital of Southwest Medical University,Luzhou,646000,China.

To investigate the prevalence and affecting factors of laryngopharyngeal reflux disease(LPRD) in otolaryngology head and neck surgery in Chongqing,and to provide a basis for the clinical diagnosis and therapy of LPRD. Multi-center cross-sectional survey method and systematic sampling method were used to select patients at fifteen hospitals in Chongqing from August to November in 2019. Then reflux symptom index(RSI) was investigated. Read More

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[Functional Exams in the gastroenterology - new developments and tips for the common practice].

Dtsch Med Wochenschr 2021 04 29;146(7):441-445. Epub 2021 Mar 29.

Klinik für Gastroenterologie und Hepatologie - Charité Campus Mitte, Universitätsmedizin Berlin - Charité.

The functional gastrointestinal disorders (FGIDs) have a high prevalence and are associated with high healthcare costs. The diagnosis of these diseases could be difficult and require func-tional tests such as high-resolution manometry (HRM) of the esophagus, anorectal manometry and H2-Breathtests. Due to the COVID-19 Pandemic and the fear of infections there was a marked reduction in the number of performed exams in the last months - nevertheless some exams are necessary, in order to exclude or to diagnose important and dangerous diseases like Achalasia. Read More

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