195 results match your criteria Esophageal Atresia Tracheoesophageal Fistula


Innovative management of severe tracheobronchomalacia using anterior and posterior tracheobronchopexy.

Laryngoscope 2019 Mar 25. Epub 2019 Mar 25.

Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, U.S.A.

Objectives/hypothesis: Combined anterior and posterior tracheobronchopexy is a novel surgical approach for the management of severe tracheobronchomalacia (TBM). We present our institutional experience with this procedure. Our objective was to determine the utility and safety of anterior and posterior tracheopexy in the treatment of severe TBM. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/lary.27938
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http://dx.doi.org/10.1002/lary.27938DOI Listing
March 2019
10 Reads

Postoperative noninvasive ventilation and complications in esophageal atresia-tracheoesophageal fistula.

J Pediatr Surg 2019 Jan 31. Epub 2019 Jan 31.

Pediatric Surgery, Centre Hospitalier Universitaire, Sainte-Justine, Canada; Esophageal Atresia Clinic, Department of Pediatric Gastroenterology, Centre Hospitalier Universitaire, Sainte Justine, Canada. Electronic address:

Purpose: This study examines the impact of postoperative noninvasive ventilation strategies on outcomes in esophageal atresia-tracheoesophageal fistula (EA-TEF) patients.

Methods: A single center retrospective chart review was conducted on all neonates followed at the EA-TEF Clinic from 2005 to 2017. Primary outcomes were: survival, anastomotic leak, stricture, pneumothorax, and mediastinitis. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2019.01.023DOI Listing
January 2019
3 Reads

Developmental Status of Children Operated for Esophageal Atresia with or without Tracheoesophageal Fistula Along with Maternal Stress, Their Quality of life, and Coping Abilities at AIIMS, New Delhi.

Eur J Pediatr Surg 2019 Feb 31;29(1):125-131. Epub 2018 Dec 31.

Department of Pediatric Surgery, All India Institute of Medical Sciences, Delhi, India.

Introduction:  Esophageal atresia with or without tracheoesophageal fistula (EA with or without TEF) is one of the neonatal surgical emergencies requiring surgical intervention in the early neonatal period, influencing the developmental outcome in the operated children. This study was aimed to assess the developmental status of children operated for EA with or without TEF along with maternal stress, their quality of life (QOL), and coping abilities.

Materials And Methods:  A descriptive cross-sectional survey was conducted on 51 children aged up to 5 years after EA with or without TEF repair and their mothers' in a tertiary care facility. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676825
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http://dx.doi.org/10.1055/s-0038-1676825DOI Listing
February 2019
3 Reads

Severe haemophilia A in a neonate presenting as haemopneumothorax after tracheo-oesophageal fistula-oesophageal atresia repair.

BMJ Case Rep 2018 Nov 8;2018. Epub 2018 Nov 8.

Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.

A male infant with oesophageal atresia and distal tracheo-oesophageal fistula (TEF type C) underwent right thoracotomy and transpleural repair of TEF on day 4 of life. He did not have a family history of coagulation disorders. A preoperative finding of prolonged partial thromboplastin time (PTT)>200 s was overlooked, and he went to surgery. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22552
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http://dx.doi.org/10.1136/bcr-2018-225526DOI Listing
November 2018
14 Reads

Relationships between hospital and surgeon operative volumes and outcomes of esophageal atresia/tracheoesophageal fistula repair.

J Pediatr Surg 2019 Jan 5;54(1):44-49. Epub 2018 Oct 5.

Center for Surgical Outcomes Research, The Research Institute at Nationwide Children's Hospital, Columbus, OH, USA. Electronic address:

Purpose: Most pediatric surgeons perform <2 esophageal atresia and tracheoesophageal fistula (EA/TEF) repairs annually. We aimed to determine whether higher surgeon and hospital volumes are associated with better outcomes after EA/TEF repair.

Methods: Neonates with a diagnosis and repair of EA/TEF at their index hospital admission in the Pediatric Health Information System from 1/2000 to 9/2015 were included. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223468183065
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http://dx.doi.org/10.1016/j.jpedsurg.2018.10.037DOI Listing
January 2019
8 Reads

Prevalence and natural history of scoliosis and associated congenital vertebral anomalies in patients operated for esophageal atresia with or without tracheoesophageal fistula.

J Pediatr Surg 2018 Sep 9. Epub 2018 Sep 9.

University of Montreal, Montreal, Canada; CHU Sainte-Justine, Montreal, Canada; Hôpital du Sacré-Coeur, Montreal, Canada. Electronic address:

Background: Scoliosis has been reported after repair of esophageal atresia with or without tracheoesophageal fistula (EA-TEF). This study aims to investigate the prevalence and natural history of scoliosis and associated congenital vertebral anomalies in patients operated for EATEF.

Methods: A retrospective review of patients operated for EA-TEF with radiological examination for the presence of scoliosis or associated spine congenital anomalies was done on 106 patients (ages 5-19 years). Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.08.049DOI Listing
September 2018
6 Reads

Vocal cord dysfunction following esophageal atresia and tracheoesophageal fistula (EA/TEF) repair.

J Pediatr Surg 2018 Sep 9. Epub 2018 Sep 9.

Division of General and Thoracic Surgery, The Hospital for Sick Children, University of Toronto, ON, Canada. Electronic address:

Background: The purpose of this study was to determine risk factors and long-term outcomes in patients with esophageal atresia +/-tracheoesophageal fistula (EA/TEF) with vocal cord dysfunction (VCD) owing to recurrent laryngeal nerve (RLN) injury.

Method: A retrospective chart review was performed for EA/TEF patients repaired at our institution from 1999 to 2014 (REB #1000032265).

Results: Of 197 patients, 22 (11. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223468183054
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http://dx.doi.org/10.1016/j.jpedsurg.2018.08.041DOI Listing
September 2018
16 Reads

Hypertrophic pyloric stenosis following repair of oesophageal atresia and tracheo-oesophageal fistula in a neonate.

BMJ Case Rep 2018 Sep 21;2018. Epub 2018 Sep 21.

Department of Pediatric Surgery, School of Medicine, Harran University, Sanliurfa, Turkey.

Development of hypertrophic pyloric stenosis (HPS) after a few weeks of repair of an oesophageal atresia (OA) and tracheo-oesophageal fistula (TOF) is a rare condition in early infancy. Although vomiting or feeding intolerance in operated cases of OA+TOF are attributed to oesophageal stricture, gastro-oesophageal reflux and oesophageal dysmotility, it may also be caused by HPS. Herein, we report a newborn infant who had OA and TOF operation on day 2 of life and diagnosed to have HPS at 15th day of age. Read More

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420448/
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https://link.springer.com/content/pdf/10.1007%2FBF02664059.p
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http://europepmc.org/articles/PMC4420448
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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22629
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http://dx.doi.org/10.1136/bcr-2018-226292DOI Listing
September 2018
13 Reads

Infants with esophageal atresia and right aortic arch: Characteristics and outcomes from the Midwest Pediatric Surgery Consortium.

J Pediatr Surg 2019 Apr 21;54(4):688-692. Epub 2018 Aug 21.

Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.

Purpose: Right sided aortic arch (RAA) is a rare anatomic finding in infants with esophageal atresia with or without tracheoesophageal fistula (EA/TEF). In the presence of RAA, significant controversy exists regarding optimal side for thoracotomy in repair of the EA/TEF. The purpose of this study was to characterize the incidence, demographics, surgical approach, and outcomes of patients with RAA and EA/TEF. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.08.002DOI Listing
April 2019
7 Reads

State of Play: Eight Decades of Surgery for Esophageal Atresia.

Eur J Pediatr Surg 2019 Feb 15;29(1):39-48. Epub 2018 Aug 15.

Department of Pediatric Surgery, Hannover Medical School, Hannover, Germany.

Aim:  Surgical expertise and advances in technical equipment and perioperative management have led to enormous progress in survival and morbidity of patients with esophageal atresia (EA) in the last decades. We aimed to analyze the available literature on surgical outcome of EA for the past 80 years.

Materials And Methods:  A PubMed literature search was conducted for the years 1944 to 2017 using the keywords "esophageal/oesophageal atresia," "outcome," "experience," "management," and "follow-up/follow up. Read More

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http://dx.doi.org/10.1055/s-0038-1668150DOI Listing
February 2019
7 Reads

Vocal cord paralysis appears to be an acquired lesion in children with repaired esophageal atresia/tracheoesophageal fistula.

Int J Pediatr Otorhinolaryngol 2018 Sep 19;112:45-47. Epub 2018 Jun 19.

Respiratory Unit, Academic Department of Pediatrics, Bambino Gesù Children's Hospital, Piazza di Sant'Onofrio, 4, 00165 Roma, RM, Italy. Electronic address:

Objectives: Determine whether vocal cord paresis or paralysis (VCP/P) following surgical repair of congenital esophageal atresia/tracheoesophageal fistula (EA/TEF) is generally a primary anomaly, or is secondary to EA/TEF repair.

Methods: We carried out a retrospective study based on a recently published protocol, which included the systematic performance of a laryngo-tracheo-bronchoscopy before and after EA/TEF repair.

Results: There were 105 patients with EA/TEF referred for multidisciplinary follow-up, between 2010 and 2015. Read More

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http://dx.doi.org/10.1016/j.ijporl.2018.06.031DOI Listing
September 2018
21 Reads
1.320 Impact Factor

Long-term Quality of Life in Neonatal Surgical Disease.

Ann Surg 2018 Sep;268(3):497-505

Children's Hospital of Wisconsin and Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.

Objective: This prospective observational study was designed to assess Pediatric Quality of Life (PedsQL) after surgical treatment for congenital diaphragmatic hernia (CDH), esophageal atresia/tracheoesophageal fistula (EA/TEF), Hirschsprung disease (HD), gastroschisis (GAS), omphalocele (OMP), and necrotizing enterocolitis (NEC).

Summary Of Background Data: Improvements in neonatal and surgical care have led to increased survival for many newborn conditions. Quality of life in these patients is seldom explored in a longitudinal manner. Read More

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http://dx.doi.org/10.1097/SLA.0000000000002918DOI Listing
September 2018
8 Reads

Esophageal Atresia with Tracheoesophageal Fistula and Gastroesophageal Reflux in Children: Dental Considerations and Case Report.

J Clin Pediatr Dent 2018;42(4):256-261. Epub 2018 May 11.

Background: Esophageal Atresia (EA) is defined as the congenital interruption of the continuity of the esophagus. Pediatric patients also have other congenital conditions, such as Tracheo-Esophageal Fistula (TEF).

Case Report: A 7-year-old male with TEF referred by a Pediatric Cardiologist, with the principal complaint of "severe and generalized tooth wearing". Read More

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http://dx.doi.org/10.17796/1053-4628-42.4.3DOI Listing
November 2018
2 Reads

Successful Management of Chylothorax With Etilefrine: Case Report in 2 Pediatric Patients.

Pediatrics 2018 05;141(5)

Hospital de Emergencias Pediatricas, Lima, Perú; and

Chylothorax is defined as the accumulation of chyle within the pleural space. Originally described in 1917 by Pisek, it is the most common cause of pleural effusion in the neonatal period. The leading cause of chylothorax is laceration of the thoracic duct during surgery, which occurs in 0. Read More

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http://dx.doi.org/10.1542/peds.2016-3309DOI Listing
May 2018
7 Reads

Identification of rare heterozygous missense mutations in FANCA in esophageal atresia patients using next-generation sequencing.

Gene 2018 Jun 3;661:182-188. Epub 2018 Apr 3.

Department of Cardiothoracic Surgery, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu 210000, China. Electronic address:

Esophageal atresia and tracheoesophageal fistula (EA/TEF) are relatively common malformations in newborns, but the etiology of EA/TEF remains unknown. Fanconi anemia (FA) complementation group A (FANCA) is a key component of the FA core complex and is essential for the activation of the DNA repair pathway. The middle region (amino acids 674-1208) of FANCA is required for its interaction with FAAP20. Read More

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http://dx.doi.org/10.1016/j.gene.2018.03.097DOI Listing
June 2018
50 Reads

Oral feeding outcomes in infants with esophageal atresia and tracheoesophageal fistula.

J Pediatr Surg 2018 May 7;53(5):929-932. Epub 2018 Feb 7.

Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Alberta, Edmonton, AB, Canada.

Purpose: The purpose of this study was to explore oral feeding outcomes in infants born with type-C esophageal atresia and tracheoesophageal fistula (EA/TEF).

Methods: A retrospective cohort study of all infants born between January 2005 and December 2015 undergoing surgery for type-C EA/TEF at the University of Alberta Hospital was performed.

Results: Fifty-seven infants were identified, of which 61. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.02.018DOI Listing
May 2018
4 Reads

Novel thoracoscopic navigation surgery for neonatal chylothorax using indocyanine-green fluorescent lymphography.

J Pediatr Surg 2018 Jun 1;53(6):1246-1249. Epub 2018 Feb 1.

Department of Pediatric Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa, Nagoya 466-8550, Japan.

Background: Postoperative chylothorax after surgery for esophageal atresia/tracheoesophageal fistula (TEF) is a rare but serious complication, especially in neonates. This study aimed to identify the thoracic duct and ligate chylous leakage sites, using thoracoscopic navigation of an indocyanine-green (ICG)-based near-infrared (NIR) fluorescence imaging system.

Methods: From November 2014 to April 2017, thoracoscopic intraoperative ICG-NIR imaging was performed in 10 newborns (11 surgeries) with first TEF operation or with persistent postoperative chylothorax after TEF operation. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2018.01.019DOI Listing
June 2018
6 Reads

Structural airway abnormalities contribute to dysphagia in children with esophageal atresia and tracheoesophageal fistula.

J Pediatr Surg 2018 Sep 31;53(9):1655-1659. Epub 2018 Jan 31.

Division of Pediatric Surgery, Department of Surgery, Emory University School of Medicine, Children's Healthcare of Atlanta, Atlanta, GA, United States.

Background: Long-term dysphagia occurs in up to 50% of repaired esophageal atresia and tracheoesophageal fistula (EA/TEF) patients. The underlying factors are unclear and may include stricture, esophageal dysmotility, or associated anomalies. Our purpose was to determine whether structural airway abnormalities (SAA) are associated with dysphagia in EA/TEF. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.12.025DOI Listing
September 2018
3 Reads

Neurodevelopmental outcomes of infants with esophageal atresia and tracheoesophageal fistula.

J Pediatr Surg 2018 Sep 31;53(9):1651-1654. Epub 2018 Jan 31.

Division of Neonatology, and Department of Pediatrics, The Hospital for Sick Children, and University of Toronto, Toronto, ON, Canada. Electronic address:

Background: Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) is a complex disorder, and most outcome data are confined to mortality and feeding-related morbidities. Our objective was to examine mortality, growth and neurodevelopmental outcomes in a large recent cohort of infants with EA/TEF.

Methods: Single center study of EA/TEF infants referred from January 2000 to December 2015. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.12.024DOI Listing
September 2018
3 Reads

Pre- and post-operative visualization of neonatal esophageal atresia/tracheoesophageal fistula via magnetic resonance imaging.

J Pediatr Surg Case Rep 2018 Feb 3;29:5-8. Epub 2017 Oct 3.

Division of Neonatology and Pulmonary Biology, Cincinnati Children's Hospital, OH 45229 USA.

Esophageal atresia (EA) is a relatively uncommon congenital anomaly, often observed in conjunction with tracheoesophageal fistula (TEF). Surgical repair in neonates typically takes place with little information about the pre-existing EA/TEF structure because there are currently no acceptable tools for evaluating EA/TEF anatomy prior to repair; chest x-ray radiograph does not identify malformation sub-type or gap length, while x-ray computed tomography (CT) demonstrate an unacceptably high exposure to ionizing radiation. There is a need for safe imaging methods to evaluate pre-operative EA/TEF anatomy, which would add value in surgical planning; this need may be met with high-resolution structural MRI. Read More

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http://dx.doi.org/10.1016/j.epsc.2017.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794017PMC
February 2018
6 Reads

Characteristics and outcomes of children with ductal-dependent congenital heart disease and esophageal atresia/tracheoesophageal fistula: A multi-institutional analysis.

Surgery 2018 04 8;163(4):847-853. Epub 2018 Jan 8.

Section of Cardiology, Department of Pediatrics, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA. Electronic address:

Background: Extracardiac birth defects are associated with worse outcomes in congenital heart disease (CHD). The impact of esophageal atresia/trachea-esophageal fistula (EA/TEF) on outcomes after surgery for ductal-dependent CHD is unknown.

Methods: Retrospective matched cohort study using the Pediatric Health Information System database from 07/2004 to 06/2015. Read More

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http://dx.doi.org/10.1016/j.surg.2017.09.010DOI Listing
April 2018
9 Reads

Clinical predictors and prevalence of receiving special preschool/school support in children with repaired esophageal atresia.

J Pediatr Surg 2018 Oct 28;53(10):1970-1975. Epub 2017 Nov 28.

Department of Pediatric Surgery, Queen Silvia Children's Hospital, Sahlgrenska University Hospital, 416 85 Gothenburg, Sweden; Institute of Clinical Sciences, Department of Pediatrics, Gothenburg University, The Queen Silvia Children's Hospital, 416 86 Gothenburg, Sweden. Electronic address:

Background/purpose: In a sparsely investigated field, we aimed to evaluate the use of special preschool/school support among children with repaired esophageal atresia (EA) and/or tracheoesophageal fistula (TEF), the predicting clinical factors for this support, and level of school absence.

Methods: Data on 119 EA/TEF children 2-17years old were collected through medical records and questionnaires (response rate 95%). Logistical regression analysis identified clinical predictors of special preschool/school support in the population without genetic disorders (n=105). Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.11.057DOI Listing
October 2018

Chewing Function in Children with Repaired Esophageal Atresia-Tracheoesophageal Fistula.

Eur J Pediatr Surg 2018 Dec 6;28(6):534-538. Epub 2017 Dec 6.

Department of Pediatric Surgery, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

Introduction:  Feeding problems are common in children with esophageal atresia and tracheoesophageal fistula (EA-TEF); however, chewing disorders, which may cause inability to intake solid food, have not been evaluated. Therefore, we aimed to evaluate the chewing function in children with repaired EA-TEF.

Materials And Methods:  Age, sex, the type of atresia, the type of repair, and the time to start oral feeding were recorded. Read More

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http://dx.doi.org/10.1055/s-0037-1608930DOI Listing
December 2018
7 Reads

How to Care for Patients with EA-TEF: The Known and the Unknown.

Curr Gastroenterol Rep 2017 Nov 25;19(12):65. Epub 2017 Nov 25.

Division of Pediatric Gastroenterology, Sainte-Justine Hospital, Montreal, QC, Canada.

Purpose Of Review: Guidelines were recently published highlighting why esophageal atresia (EA) patients are prone to complication risks, and the need for long-term follow-up. In this review, we will focus on how to investigate and treat potential complications, as well as the pros and cons of different investigative and treatment modalities, and what areas continue to need further research.

Recent Findings: EA patients are at high risk for gastroesophageal reflux and esophageal strictures, and the sequela that result. Read More

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http://dx.doi.org/10.1007/s11894-017-0605-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450800PMC
November 2017
12 Reads

Population-based birth defects data in the United States, 2010-2014: A focus on gastrointestinal defects.

Birth Defects Res 2017 Nov;109(18):1504-1514

Department of Community and Family Health, College of Public Health, University of South Florida, Tampa, Florida.

Background: Gastrointestinal defects are a phenotypically and etiologically diverse group of malformations. Despite their combined prevalence and clinical impact, little is known about the epidemiology of these birth defects. Therefore, the objective of the 2017 National Birth Defects Prevention Network (NBDPN) data brief was to better describe the occurrence of gastrointestinal defects. Read More

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http://dx.doi.org/10.1002/bdr2.1145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915361PMC
November 2017
21 Reads

Recurrent tracheoesophageal fistula in an adolescent without persistent symptoms: A case report.

Medicine (Baltimore) 2017 Nov;96(46):e8668

aDepartment of Respiration, Guangzhou Women and Children's Medical Center, Guangzhou Medical University bDepartment of Medical Oncology, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.

Rationale: Congenital esophageal atresia (EA) and tracheoesophageal fistula (TEF) ininfants have been treated well with surgery. Approximately 10% of children displayed recurrent fistula. In the present case, we reported recurrent TEF in an adolescent as a complication of EA/TEF in infancy. Read More

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http://dx.doi.org/10.1097/MD.0000000000008668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704839PMC
November 2017
11 Reads

Proton Pump Inhibitors May Not Be the First Line of Treatment for GERD in Infants.

J Pediatr Gastroenterol Nutr 2018 01;66(1):e26

Advocate Children's Hospital, Loyola Medical Cneter, University of Illinois, Chicago, IL.

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http://dx.doi.org/10.1097/MPG.0000000000001760DOI Listing
January 2018
3 Reads

Respiratory Morbidity in Children with Repaired Congenital Esophageal Atresia with or without Tracheoesophageal Fistula.

Int J Environ Res Public Health 2017 09 27;14(10). Epub 2017 Sep 27.

Paediatric Clinic, Department of Surgical and Biomedical Sciences, Università degli Studi di Perugia, 06123 Perugia, Italy.

Congenital esophageal atresia with or without tracheoesophageal fistula (CEA ± TEF) is a relatively common malformation that occurs in 1 of 2500-4500 live births. Despite the refinement of surgical techniques, a considerable proportion of children experience short- and long-term respiratory complications, which can significantly affect their health through adulthood. This review focuses on the underlying mechanisms and clinical presentation of respiratory morbidity in children with repaired CEA ± TEF. Read More

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http://dx.doi.org/10.3390/ijerph14101136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5664637PMC
September 2017
11 Reads

Management of recurrent tracheoesophageal fistula after esophageal atresia and follow-up.

Dis Esophagus 2017 Sep;30(9):1-8

Department of Pediatric Surgery, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine.

Recurrent tracheoesophageal fistula (rTEF) is a complex complication after the repair of esophageal atresia (EA) and remains a challenge because of difficulties in preoperative management and the substantial rates of mortality and morbidity after reoperation. By reviewing a single institution's experience in the management of rTEF and assessing the outcome, we aimed to provide an optimal approach for managing rTEF and to evaluate growth and feeding problems after reoperations. The medical records of 35 patients with rTEF treated at a single institution from June 2012 to December 2015 were reviewed, and follow-up data were collected from all survivors. Read More

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http://dx.doi.org/10.1093/dote/dox081DOI Listing
September 2017
29 Reads

Utilizing stricture indices to predict dilation of strictures after esophageal atresia repair.

J Surg Res 2017 08 10;216:172-178. Epub 2017 May 10.

Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin.

Background: Anastomotic stricture is the most common postoperative complication in infants undergoing repair of esophageal atresia with or without tracheoesophageal fistula (EA/TEF). Stricture indices (SIs) are used to predict infants at risk for stricture requiring dilation. We sought to determine the most accurate SI and optimal timing for predicting anastomotic dilation. Read More

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http://dx.doi.org/10.1016/j.jss.2017.04.024DOI Listing
August 2017
3 Reads

Basal progenitor cells bridge the development, malignant cancers, and multiple diseases of esophagus.

J Cell Physiol 2018 05 30;233(5):3855-3866. Epub 2017 Aug 30.

Institute for Laboratory Medicine, Fuzhou General Hospital, PLA, Fuzhou, Fujian, P. R. China.

The esophagus is a pivotal organ originating from anterior foregut that links the mouth and stomach. Moreover, its development involves precise regulation of multiple signal molecules and signal transduction pathways. After abnormal regulation of these molecules in the basal cells of the esophagus occurs, multiple diseases, including esophageal atresia with or without tracheoesophageal fistula, Barrett esophagus, gastroesophageal reflux, and eosinophilic esophagitis, will take place as a result. Read More

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http://dx.doi.org/10.1002/jcp.26136DOI Listing
May 2018
8 Reads

Intraoperative acidosis and hypercapnia during thoracoscopic repair of congenital diaphragmatic hernia and esophageal atresia/tracheoesophageal fistula.

Paediatr Anaesth 2017 Aug 20;27(8):841-848. Epub 2017 Jun 20.

Division of General and Thoracic Surgery, The Hospital for Sick Children, Toronto, Ontario, Canada.

Background: Intraoperative hypercapnia and acidosis have been associated with thoracoscopic repair of both congenital diaphragmatic hernia and esophageal atresia/tracheoesophageal fistula.

Aim: The aim of the present study was to investigate whether thoracoscopic repair of congenital diaphragmatic hernia or esophageal atresia/tracheoesophageal fistula was associated with acidosis and hypercapnia in a large group of neonates, and to analyze the effects of acidosis and hypercapnia on early postoperative outcomes.

Methods: We reviewed the charts of neonates who underwent open or thoracoscopic congenital diaphragmatic hernia or esophageal atresia/tracheoesophageal fistula repair (2004-2014). Read More

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http://dx.doi.org/10.1111/pan.13178DOI Listing
August 2017
18 Reads

Feeding Problems and Their Underlying Mechanisms in the Esophageal Atresia-Tracheoesophageal Fistula Patient.

Front Pediatr 2017 31;5:127. Epub 2017 May 31.

Aerodigestive Center, Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA, United States.

Feeding difficulties such as dysphagia, coughing, choking, or vomiting during meals, slow eating, oral aversion, food refusal, and stressful mealtimes are common in children with repaired esophageal atresia (EA) and the reasons for this are often multifactorial. The aim of this review is to describe the possible underlying mechanisms contributing to feeding difficulties in patients with EA and approaches to management. Underlying mechanisms for these feeding difficulties include esophageal dysphagia, oropharyngeal dysphagia and aspiration, and aversions related to prolonged gastrostomy tube feeding. Read More

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http://dx.doi.org/10.3389/fped.2017.00127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449447PMC
May 2017
4 Reads

Outcome of primary repair in extremely and very low-birth-weight infants with esophageal atresia/distal tracheoesophageal fistula.

J Pediatr Surg 2017 Oct 17;52(10):1567-1570. Epub 2017 May 17.

Department of Pediatric Surgery and Pediatric Urology, University Children's Hospital, Eberhard Karls University Tuebingen, Hoppe-Seyler-Strasse 3, 72076 Tuebingen, Germany. Electronic address:

Purpose: The optimal surgical management of extremely (ELBW) and very low-birth-weight (VLBW) neonates with esophageal atresia and distal tracheoesophageal fistula (EA/TEF) (Gross type C) is still debated. The aim of this study was to evaluate the surgical outcome of primary repair in these patients and compare it to ≥1500g neonates.

Methods: Medical records of neonates with repaired EA from 2002 to 2016 were reviewed. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.05.011DOI Listing
October 2017
55 Reads

Advanced minimal access surgery in infants weighing less than 3kg: A single center experience.

J Pediatr Surg 2018 Mar 11;53(3):503-507. Epub 2017 May 11.

Division of Pediatric Surgery, Department of Surgery, Stanford University School of Medicine, Stanford, CA, United States. Electronic address:

Background: Minimal access surgery (MAS) has gained popularity in infants less than 5kg, however, significant challenges still arise in very low weight infants.

Study Design: A retrospective chart review was performed to identify all infants weighing less than 3kg who underwent an advanced MAS or equivalent open procedure from 2009 to 2016. Advanced case types included Nissen fundoplication, duodenal atresia repair, Ladd procedure, congenital diaphragmatic hernia repair, esophageal atresia/tracheoesophageal fistula repair, diaphragmatic plication, and pyloric atresia repair. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.05.006DOI Listing
March 2018
13 Reads

Postoperative Complications and Functional Outcome after Esophageal Atresia Repair: Results from Longitudinal Single-Center Follow-Up.

J Gastrointest Surg 2017 06 19;21(6):927-935. Epub 2017 Apr 19.

Department of Pediatric and Adolescent Surgery, Medical University of Graz, Auenbruggerplatz 34, 8036, Graz, Austria.

Background: Esophageal atresia (EA) and tracheoesophageal fistula (TEF) represent major therapeutic challenges, frequently associated with serious morbidities following surgical repair. The aim of this longitudinal study was to assess temporal changes in morbidity and mortality of patients with EA/TEF treated in a tertiary-level center, focusing on postoperative complications and their impact on long-term gastroesophageal function.

Methods: One hundred nine consecutive patients with EA/TEF born between 1975 and 2011 were followed for a median of 9. Read More

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http://dx.doi.org/10.1007/s11605-017-3423-0DOI Listing
June 2017
11 Reads

Aspiration Risk and Respiratory Complications in Patients with Esophageal Atresia.

Authors:
Thomas Kovesi

Front Pediatr 2017 3;5:62. Epub 2017 Apr 3.

Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada.

Chronic, long-term respiratory morbidity (CRM) is common in patients with a history of repaired congenital esophageal atresia, typically associated with tracheoesophageal fistula (EA/TEF). EA/TEF patients are at high risk of having aspiration, and retrospective studies have associated CRM with both recurrent aspiration and atopy. However, studies evaluating the association between CRM in this population and either aspiration or atopy have reported conflicting results. Read More

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http://dx.doi.org/10.3389/fped.2017.00062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376561PMC
April 2017
1 Read

Alterations in hyolaryngeal elevation after esophageal anastomosis: A possible mechanism for airway aspiration.

J Pediatr Surg 2017 Oct 5;52(10):1580-1582. Epub 2017 Apr 5.

Hacettepe University, Faculty of Medicine, Department of Pediatric Surgery, Ankara, Turkey. Electronic address:

Aim: A prospective study was performed to evaluate anatomical alterations and hyolaryngeal elevation (HE) by videofluoroscopic swallowing study (VFSS) in patients with esophageal atresia-tracheoesophageal fistula (EA-TEF).

Methods: Patients operated for EA-TEF were evaluated for age, sex, type of atresia and time to esophageal anastomosis. All patients were evaluated by videofluoroscopic swallowing study (VFSS). Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2017.04.001DOI Listing
October 2017
10 Reads

Esophageal Atresia/Tracheoesophageal Fistula Repair Complicated by Tracheomalacia: A Case Report of Successful Management of Respiratory Distress Using Caudal Morphine.

A A Case Rep 2017 Jul;9(1):28-30

From the Departments of *Anesthesiology and Perioperative Medicine; †Surgery; ‡Pediatrics; and §Neonatology, Queen's University and Kingston General Hospital, Kingston, Ontario, Canada.

We report a case of severe respiratory distress in a neonate who was not endotracheally intubated soon after esophageal atresia/tracheoesophageal fistula (EA/TEF) repair. In this serious situation, any form of emergency respiratory support or definitive airway management may compromise the esophageal anastomosis and fistula repair. The cause of respiratory distress in the early postoperative period after EA/TEF is multifactorial, and in this case, included symptomatic tracheomalacia, which is commonly associated with EA/TEF. Read More

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http://Insights.ovid.com/crossref?an=01720097-201707010-0000
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http://dx.doi.org/10.1213/XAA.0000000000000517DOI Listing
July 2017
9 Reads

Effect of Swallowing Rehabilitation Protocol on Swallowing Function in Patients with Esophageal Atresia and/or Tracheoesophageal Fistula.

Eur J Pediatr Surg 2017 Dec 17;27(6):526-532. Epub 2017 Mar 17.

Department of Pediatric Surgery, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

 The aim of this study was to evaluate the results of Swallowing Rehabilitation Protocol (SRP) on swallowing function (SF) of esophageal atresia and tracheoesophageal fistula (EA-TEF) patients with pharyngeal swallowing disorder.  In this study, 24 children with EA-TEF who had deglutitive and respiratory problems were grouped into either study ( = 12) or control group ( = 12) by basic randomization. Study group received the SRP including neuromuscular electrical stimulation, thermal tactile stimulation, and hyolaryngeal mobilization. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0037-1599231
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http://dx.doi.org/10.1055/s-0037-1599231DOI Listing
December 2017
9 Reads

Intestinal Metaplasia of the Esophagus in Children With Esophageal Atresia.

J Pediatr Gastroenterol Nutr 2017 07;65(1):e1-e4

*Esophageal Atresia Clinic Sainte-Justine University Health Centre, Université de Montréal, Montreal, Canada†Reference Centre for Congenital and Malformative Esophageal Diseases, CHU Lille, University Lille2, Lille, France‡Sydney Children's Hospital, Sydney, NSW, Australia§Department of Pathology, Sainte-Justine University Health Centre, Université de Montréal, Montreal, Canada.

Objectives: Patients with esophageal atresia/tracheoesophageal fistula (EA-TEF) can develop Barrett esophagus as a long-term consequence of their condition. Intestinal metaplasia (IM), a risk factor for developing adenocarcinoma of the esophagus, has not been well characterized in the pediatric population.

Methods: Retrospective review of patients with EA-TEF followed at 3 academic pediatric centers between the years 1997 and 2014. Read More

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http://dx.doi.org/10.1097/MPG.0000000000001558DOI Listing
July 2017
12 Reads

Surveillance in Patients With Esophageal Atresia/Tracheoesophageal Fistula.

Curr Gastroenterol Rep 2017 Jan;19(1)

Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, NY, USA.

Purpose Of Review: Esophageal atresia/tracheoesophageal fistula (EA/TEF) is a congenital aerodigestive anomaly with high survival rates after surgical repair. Care should now be focused on prevention of long-term complications using appropriate surveillance techniques.

Recent Findings: The incidence of gastroesophageal reflux disease (GERD) is high in patients with EA/TEF. Read More

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http://dx.doi.org/10.1007/s11894-017-0541-5DOI Listing
January 2017
1 Read

Quality of Life after Surgical Treatment for Esophageal Atresia: Long-Term Outcome of 154 Patients.

Eur J Pediatr Surg 2017 Oct 6;27(5):443-448. Epub 2017 Jan 6.

Department of Pediatric Surgery and Pediatric Urology, Children's Hospital, Cologne, Germany.

 The short- and long-term surgical results in patients with esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) have been described in depth from a physician's perspective. Contrarily, the perception and coping strategies of affected patients and their parents have rarely been reported. The aim of this study was to generate data on this matter. Read More

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http://dx.doi.org/10.1055/s-0036-1597956DOI Listing
October 2017
5 Reads

Esophageal Atresia with or without Tracheoesophageal Fistula (EA/TEF): Association of Different EA/TEF Subtypes with Specific Co-occurring Congenital Anomalies and Implications for Diagnostic Workup.

Eur J Pediatr Surg 2018 Apr 6;28(2):176-182. Epub 2017 Jan 6.

Department of Neonatology and Pediatric Intensive Care, Children's Hospital, University of Bonn, Bonn, Germany.

Background:  Esophageal atresia with or without tracheoesophageal fistula (EA/TEF) represents the most common developmental malformation of the upper digestive tract. It is classified into six subtypes according to the classification of Vogt, depending on anatomical variation of this malformation. Around 50% of the patients with EA/TEF present additional anomalies, which often influence, next to the EA/TEF subtype, the overall prognosis of EA/TEF newborns. Read More

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http://dx.doi.org/10.1055/s-0036-1597946DOI Listing
April 2018
14 Reads

Routine post-operative esophagram Is not necessary after repair of esophageal atresia.

Am J Surg 2017 Apr 30;213(4):640-644. Epub 2016 Dec 30.

Children's Hospital Los Angeles, Division of Pediatric Surgery, 4650 Sunset Blvd, Los Angeles, CA 90027, USA. Electronic address:

Introduction: Esophagrams are routinely performed following repair of esophageal atresia (EA) with or without tracheoesophageal fistula (TEF); however, its utility has not been validated.

Methods: EA/TEF repair performed from 2003 to 2014 at a single pediatric hospital and from 2004 to 2014 in the Pediatric Health Information System (PHIS) database were retrospectively reviewed to determine utility of esophagrams.

Results: Esophagram was performed in 99% of patients at our institution (N = 105). Read More

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http://dx.doi.org/10.1016/j.amjsurg.2016.12.020DOI Listing
April 2017
9 Reads

Development and stem cells of the esophagus.

Semin Cell Dev Biol 2017 06 19;66:25-35. Epub 2016 Dec 19.

Division of Digestive and Liver Diseases and Center for Human Development, Department of Medicine, Columbia University, NY 10032, USA. Electronic address:

The esophagus is derived from the anterior portion of the developmental intermediate foregut, a structure that also gives rise to other organs including the trachea, lung, and stomach. Genetic studies have shown that multiple signaling pathways (e.g. Read More

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http://dx.doi.org/10.1016/j.semcdb.2016.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474349PMC
June 2017
8 Reads

Vertebral defect, anal atresia, cardiac defect, tracheoesophageal fistula/esophageal atresia, renal defect, and limb defect association with Mayer-Rokitansky-Küster-Hauser syndrome in co-occurrence: two case reports and a review of the literature.

J Med Case Rep 2016 Dec 21;10(1):374. Epub 2016 Dec 21.

Department of Clinical Genetics, Aalborg University Hospital, Ladegårdsgade 5, Aalborg, 9000, Denmark.

Background: The vertebral defect, anal atresia, cardiac defect, tracheoesophageal fistula/esophageal atresia, renal defect, and limb defect association and Mayer-Rokitansky-Küster-Hauser syndrome are rare conditions. We aimed to present two cases with the vertebral defect, anal atresia, cardiac defect, tracheoesophageal fistula/esophageal atresia, renal defect, and limb defect association and Mayer-Rokitansky-Küster-Hauser co-occurrence from our local surgical center and through a systematic literature search detect published cases. Furthermore, we aimed to collect existing knowledge in the embryopathogenesis and genetics in order to discuss a possible link between the vertebral defect, anal atresia, cardiac defect, tracheoesophageal fistula/esophageal atresia, renal defect, and limb defect association and Mayer-Rokitansky-Küster-Hauser syndrome. Read More

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http://dx.doi.org/10.1186/s13256-016-1127-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178070PMC
December 2016
48 Reads

Perioperative management and outcomes of esophageal atresia and tracheoesophageal fistula.

J Pediatr Surg 2017 Aug 5;52(8):1245-1251. Epub 2016 Dec 5.

Division of Pediatric Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, United States.

Background/purpose: Esophageal atresia/tracheoesophageal fistula (EA/TEF) is a rare congenital anomaly lacking contemporary data detailing patient demographics, medical/surgical management and outcomes. Substantial variation in the care of infants with EA/TEF may affect both short- and long-term outcomes. The purpose of this study was to characterize the demographics, management strategies and outcomes in a contemporary multi-institutional cohort of infants diagnosed with EA/TEF to identify potential areas for standardization of care. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2016.11.046DOI Listing
August 2017
58 Reads

Characterization of the upper pouch tracheo-oesophageal fistula in oesophageal atresia.

J Pediatr Surg 2017 Feb 13;52(2):231-234. Epub 2016 Nov 13.

Department of Paediatric Surgery, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address:

Aim: A small proportion of infants with oesophageal atresia (OA) are thought to have a proximal tracheoesophageal fistula (TOF). Failure to recognize these can hamper mobilization of the upper pouch and lead to life-threatening episodes of aspiration once oral feeding starts. We reviewed our experience of upper pouch fistulae to identify characteristic features of proximal TOF. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2016.11.009DOI Listing
February 2017
1 Read