540 results match your criteria Erythroplasia of Queyrat Bowen Disease of the Glans Penis


Penile intraepithelial neoplasia: Nomenclature, incidence and progression to malignancy in the Netherlands.

Int J Urol 2018 Dec 3. Epub 2018 Dec 3.

Department of Urology, University Medical Center Utrecht, Utrecht, the Netherlands.

Objective: To determine the incidence of penile intraepithelial neoplasia in the Netherlands using a nationwide histopathology registry and to discuss the nomenclature of premalignant penile lesions.

Methods: Data from patients in the Netherlands diagnosed with a premalignant penile lesion between January 1998 and December 2007 were collected from the nationwide histopathology registry (PALGA); this database covers all pathology reports of inhabitants in the Netherlands. The premalignant lesions included were erythroplasia of Queyrat; Bowen's disease; bowenoid papulosis; mild, moderate and severe dysplasia; and carcinoma in situ of the penis. Read More

View Article
December 2018

Accuracy of dermoscopy in distinguishing erythroplasia of Queyrat from common forms of chronic balanitis: results from a multicentric observational study.

J Eur Acad Dermatol Venereol 2018 Nov 23. Epub 2018 Nov 23.

Department of Medical Area, Institute of Dermatology, University of Udine, Udine, Italy.

Background: Clinical differentiation of erythroplasia of Queyrat (EQ) and chronic forms of balanitis may be challenging, especially in early phases or in overlapping cases. Dermoscopy has been shown to be a useful supportive tool in facilitating the distinction between tumoral and inflammatory skin conditions; yet, data on EQ and balanitis are scarce or sparse.

Objectives: To systematically assess the dermoscopic features of both EQ and common forms of chronic balanitis and to investigate the accuracy of dermoscopy in distinguishing these conditions. Read More

View Article
November 2018
2 Reads

[Penile intra-epithelial neoplasia].

Prog Urol 2018 Sep 22;28(10):466-474. Epub 2018 Jun 22.

Service de dermatologie, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.

Introduction: Penile intra-epithelial neoplasia (PIN) are precancerous lesions, characterized by architectural and cytological abnormalities of the genital epithelium, from which can arise squamous carcinomas.

Methods: A literature review was performed on the Medline database, considering the articles listed between October 2007 and October 2017 dealing with PIN, using the following keywords "intraepithelial neoplasia" or "Bowen's disease" or "erythroplasia of Queyrat" or "bowenoid papulosis" and "penis ». Papers were selected according to their language (English and French) and their relevance. Read More

View Article
September 2018
6 Reads

Risk factors and etiopathogenesis of potentially premalignant oral epithelial lesions.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 20;125(6):603-611. Epub 2018 Mar 20.

UCL Eastman Dental Institute, London, UK; Oral Theme of the UCL/UCLH NIHR Biomedical Research Centre, UK.

Potentially malignant oral mucosal disease has some ability to give rise to malignancy of the oral epithelium, that is, oral squamous cell carcinoma (OSCC). The present article provides a succinct review of the possible or probable causes of potentially premalignant oral epithelial lesions. There is a focus upon studies that examined the causes or etiologic associations with clinically likely or histopathologically detectable oral epithelial dysplasia. Read More

View Article

Development of squamous cell carcinoma from erythroplasia of Queyrat following photodynamic therapy.

Eur J Dermatol 2018 Jun;28(3):405-406

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

View Article
June 2018
2 Reads

Molecular markers associated with development and progression of potentially premalignant oral epithelial lesions: Current knowledge and future implications.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 4;125(6):650-669. Epub 2018 Apr 4.

Pathology, Surgical and Hospital Dentistry, University of Louisville, USA.

Identification and management of potentially premalignant oral epithelial lesions (PPOELs) at highest risk of malignant transformation holds great promise for successful secondary prevention of oral squamous cell carcinoma, potentially reducing oral cancer morbidity and mortality. However, to date, neither clinical nor histopathologic validated risk predictors that can reliably predict which PPOELs will definitively progress to malignancy have been identified. In addition, the management of PPOELs remains a major challenge. Read More

View Article
June 2018
2 Reads

Introduction to the Oral and Maxillofacial Pathology focus issue on "Preneoplastic oral epithelial lesions".

Authors:
Paul C Edwards

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 6;125(6):574. Epub 2018 Apr 6.

Section Editor, Oral and Maxillofacial Pathology; Professor, Dept. of Oral Pathology, Medicine, and Radiology, Indiana University School of Dentistry, Indianapolis, IN, USA.

View Article

Alterations in the expression of DNA damage response-related molecules in potentially preneoplastic oral epithelial lesions.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 22;125(6):637-649. Epub 2018 Mar 22.

Department of Oral Medicine and Pathology, School of Dentistry, National and Kapodistrian University of Athens, Greece.

Objectives: The aim of this study was to evaluate the expression levels of DNA damage response (DDR) markers in potentially preneoplastic oral epithelial lesions (PPOELs).

Study Design: Immunohistochemical expression of DDR markers (γΗ2 ΑΧ, pChk2, 53 BP1, p53, and phosphorylated at Ser 15 p53) was assessed in 41 oral leukoplakias, ranging from hyperplasia (H) to dysplasia (D) and in comparison with oral squamous cell carcinoma (OSCC) and normal mucosa (NM). Statistical and receiver operating characteristic curve analysis were performed. Read More

View Article

Special focus issue on potentially premalignant oral epithelial lesions: introduction and perspective.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 6;125(6):575-576. Epub 2018 Apr 6.

Diplomate, American Board of Oral and Maxillofacial Pathology; Fellow, American Academy of Oral and Maxillofacial Pathology; Fellow, American Academy of Oral Medicine; Associate Professor, Department of Oral Pathology and Medicine, Dental School, University of Athens, Greece; Secretary General, European Association of Oral Medicine; President, Hellenic Society of Oral Medicine and Oral Pathology.

View Article

Clinical features and presentation of oral potentially malignant disorders.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 4;125(6):582-590. Epub 2018 Apr 4.

Emeritus Professor, King's College London, UK; WHO Collaborating Centre for Oral Cancer, London, UK. Electronic address:

Oral potentially malignant disorders (OPMDs) are conditions that precede the onset of invasive cancers of the oral cavity. The term embraces precancerous lesions and conditions referred to in earlier World Health Organization (WHO) definitions. Leukoplakia is the most common OPMD; erythroplakia, although rare, is more serious. Read More

View Article

Management update of potentially premalignant oral epithelial lesions.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 23;125(6):628-636. Epub 2018 Mar 23.

Department of Oral and Maxillofacial Surgery, North Memorial Medical Center, Minneapolis, MN, USA. Electronic address:

The term oral potentially malignant disorders, proposed at the World Health Organization workshop in 2005, has now been renamed potentially premalignant oral epithelial lesions (PPOELs). It is important to differentiate among PPOELs, which is a broad term to define a wide variety of clinical lesions, and oral epithelial dysplasia, which should be reserved specifically for lesions with biopsy-proven foci of dysplasia. PPOELs encompass lesions that include leukoplakia, erythroplakia, erythroleukoplakia, lichen planus, and oral submucous fibrosis. Read More

View Article
June 2018
5 Reads

Nonvenereal Penile Dermatoses: A Retrospective Study.

Indian Dermatol Online J 2018 Mar-Apr;9(2):96-100

University Clinic of Dermatology, Hospital de Santa Maria, Lisbon, Portugal.

Context: A variety of nonvenereal diseases can affect the penis and diminish quality of life. Many present similar clinical features and a cutaneous biopsy may be necessary to clarify the diagnosis.

Aims: To characterize nonvenereal penile dermatoses with histological confirmation in a southwestern Europe hospital during a 9-year period. Read More

View Article
April 2018
5 Reads

Noninvasive diagnostic adjuncts for the evaluation of potentially premalignant oral epithelial lesions: current limitations and future directions.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 9;125(6):670-681. Epub 2018 Mar 9.

Department of Diagnostic and Biomedical Sciences, University of Texas School of Dentistry, Houston, TX, USA. Electronic address:

Potentially premalignant oral epithelial lesions (PPOELs) are a group of clinically suspicious conditions, of which a small percentage will undergo malignant transformation. PPOELs are suboptimally diagnosed and managed under the current standard of care. Dysplasia is the most well-established marker to distinguish high-risk PPOELs from low-risk PPOELs, and performing a biopsy to establish dysplasia is the diagnostic gold standard. Read More

View Article
June 2018
1 Read

Oral epithelial dysplasia, atypical verrucous lesions and oral potentially malignant disorders: focus on histopathology.

Authors:
Susan Müller

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 1;125(6):591-602. Epub 2018 Mar 1.

Emory University School of Medicine, Atlanta Oral Pathology, Decatur, GA, USA. Electronic address:

The term oral potentially malignant disorders (OPMDs) describes a recognizable group of mucosal diseases that have a risk of progressing to squamous cell carcinoma. Oral leukoplakia, the most common OPMD, has a 1% prevalence and reported malignant transformation rates of 2% to 5%. Other OPMDs include erythroplakia, erythroleukoplakia, submucous fibrosis, lesions of reverse smokers, and inherited genetic disorders, such as Fanconi anemia. Read More

View Article
June 2018
25 Reads

Oral erythroplakia-What is it?

Authors:
P Holmstrup

Oral Dis 2018 Mar;24(1-2):138-143

Section of Periodontology, Oral Microbiology, Oral Radiology, Oral Surgery, Oral Physiology, and Community Dentistry, Department of Odontology, University of Copenhagen, Copenhagen, Denmark.

Oral erythroplakia is a rare type of lesion, and little is known about the origin of the lesion. It has traditionally been described as the red counterpart of oral leukoplakia, which implies that it is a red lesion that cannot be characterized clinically or pathologically as any other definable lesion. A definition by exclusion is less satisfactory than a positive description to define a lesion, and as erythroplakia probably is related to lichenoid lesions, a new approach to perceive the lesion is proposed based on the clinical features of a fiery red, sharply demarcated lesion situated at a slightly lower level than the surrounding mucosa. Read More

View Article

Oral potentially malignant disorders: risk of progression to malignancy.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 29;125(6):612-627. Epub 2017 Dec 29.

UWA Dental School, The University of Western Australia, Nedlands, Australia.

Oral potentially malignant disorders (OPMDs) have a statistically increased risk of progressing to cancer, but the risk varies according to a range of patient- or lesion-related factors. It is difficult to predict the risk of progression in any individual patient, and the clinician must make a judgment based on assessment of each case. The most commonly encountered OPMD is leukoplakia, but others, including lichen planus, oral submucous fibrosis, and erythroplakia, may also be seen. Read More

View Article
June 2018
5 Reads

Historical perspective and nomenclature of potentially malignant or potentially premalignant oral epithelial lesions with emphasis on leukoplakia-some suggestions for modifications.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 06 29;125(6):577-581. Epub 2017 Dec 29.

VU University Medical Center (VUmc)/Academic Centre for Dentistry Amsterdam (ACTA), Department of Oral and Maxillofacial Surgery and Oral Pathology, Amsterdam, The Netherlands. Electronic address:

Of the potentially (pre)maligant oral epithelial lesions, leukoplakia is the most common. A brief overview of the various definitions of leukoplakia that have been used in the past is presented here. A proposal has been made to modify the current definition. Read More

View Article
June 2018
1 Read

Bibliometric analysis of a century of research on oral erythroplakia and leukoplakia.

J Oral Pathol Med 2018 Apr 13;47(4):388-395. Epub 2018 Feb 13.

INSERM 1052, CNRS 5286, Centre de Recherche en Cancérologie de Lyon, Centre Léon Bérard, Univ Lyon, Université Claude Bernard Lyon 1, Lyon, France.

Background: Oral squamous cell carcinoma is a major cause of cancer-associated morbidity and mortality and may develop from oral erythroplakia and leukoplakia (OEL), the most common oral potentially malignant lesions. Our objective was to provide a descriptive overview of the global research activity on OEL over the past decades.

Methods: We performed a systematic bibliometric analysis of articles and reviews on OEL up to December 31st 2016 using the SCOPUS database. Read More

View Article
April 2018
2 Reads

Combination of imiquimod with cryotherapy in the treatment of penile intraepithelial neoplasia.

JAAD Case Rep 2017 Nov 6;3(6):546-549. Epub 2017 Nov 6.

Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.

View Article
November 2017
5 Reads

Oral verruciform xanthoma and erythroplakia associated with chronic graft-versus-host disease: a rare case report and review of the literature.

BMC Res Notes 2017 Nov 28;10(1):631. Epub 2017 Nov 28.

Department of Surgical, Oncological and Oral Sciences, University of Palermo, Via del Vespro 129, 90127, Palermo, Italy.

Background: Oral verruciform xanthoma is an uncommon benign lesion. Although oral verruciform xanthoma occurs in healthy individuals, it has been also reported in association with some inflammatory conditions. The aim of this study is to report a case of oral verruciform xanthoma associated with chronic graft-versus-host disease and to review the literature on this topic. Read More

View Article
November 2017
9 Reads

Urologic Dermatology: a Review.

Curr Urol Rep 2017 Aug;18(8):62

Virginia Mason Medical Center, Seattle, WA, USA.

Purpose Of Review: Genital dermatology represents a challenge to many providers. Though dermatologic lesions involving the genitalia may present to any of a number of practices, ranging from primary care to urology, gynecology, and dermatology, few training programs provide significant training regarding the diagnosis and management of genital dermatologic lesions. The purpose of this review is to provide urologists with an overview of common genital dermatological lesions that may be encountered in a clinic. Read More

View Article
August 2017
28 Reads

Photodynamic treatment outcomes of potentially-malignant lesions and malignancies of the head and neck region: A systematic review.

J Investig Clin Dent 2018 Feb 8;9(1). Epub 2017 May 8.

Department of Conservative and Endodontics, HSRS Dental College and Hospital, Hingoli, Maharashtra, India.

Aim: The aim of the present study was to systematically review the efficacy of photodynamic therapy (PDT) in the management of oral potentially-malignant disorders (PMDS) and head and neck squamous cell carcinoma (HNSCC).

Methods: From 1985 to 2015, PubMed/Medline, Google Scholar, EMBASE, and ISI Web of Knowledge were searched using different combinations of the following key words: PDT, oral precancer, leukoplakia, erythroplakia, erythroleukoplakia, verrucous hyperplasia, oral submucous fibrosis, and HNSCC. Review articles, experimental studies, case reports, commentaries, letters to the editor, unpublished articles, and articles published in languages other than English were excluded. Read More

View Article
February 2018
13 Reads

Erythroplasia of Queyrat treated with topical 5-fluorouracil.

An Bras Dermatol 2016 Sep-Oct;91(5 suppl 1):42-44

Faculdade de Medicina de São José do Rio Preto (FAMERP) - São José do Rio Preto (SP), Brazil.

We report a 33-year-old male patient diagnosed with erythroplasia of Queyrat. The patient had an erythematous and eroded lesion affecting more than 50% of the glans associated with bleeding and local pain. Despite previous indication of penectomy, he was successfully treated with topical 5-fluorouracil. Read More

View Article
July 2017
3 Reads

Treatment of Carcinoma In Situ of the Glans Penis With Topical Imiquimod Followed by Carbon Dioxide Laser Excision.

Clin Genitourin Cancer 2017 06 18;15(3):e483-e487. Epub 2017 Jan 18.

Department of Urology, IRCCS Fondazione, Istituto Nazionale dei Tumori, Milan, Italy.

Background: Different approaches have been described in published studies for carcinoma in situ (CIS) of the glans penis (erythroplasia of Queyrat), including topical chemotherapy or immunotherapy and laser or surgical excision. We evaluated the efficacy of topical imiquimod (IQ) followed by carbon dioxide laser ablation of the lesion.

Patients And Methods: From 2010 to 2015, 10 patients affected by CIS of the glans were treated by IQ, followed by carbon dioxide laser ablation. Read More

View Article
June 2017
12 Reads

The current role of in vivo reflectance confocal microscopy within the continuum of actinic keratosis and squamous cell carcinoma: a systematic review.

Eur J Dermatol 2016 Dec;26(6):549-565

Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.

Background: Clinical differentiation between actinic keratosis (AK), squamous cell carcinoma (SCC) in situ, and invasive SCC and its variants may be difficult. Reflectance confocal microscopy (RCM) is a non-invasive technique for in vivo skin imaging.

Objectives: To explicate the diagnostic and monitoring use of RCM within the spectrum of AK and SCC, and evaluate the accuracy of RCM for these diagnoses relative to histopathology. Read More

View Article
December 2016
6 Reads

[Precancerous lesions of the buccal epithelium].

Ann Dermatol Venereol 2017 Feb 6;144(2):100-108. Epub 2016 Dec 6.

Service de pathologie, hôpital Saint-Louis, 1, avenue Claude-Vellefaux, 75010 Paris, France.

Squamous cell carcinomas of the oral cavity and lips consistently have a high incidence (they constitute the fifth most common form of cancer in France) and carry a heavy prognosis, particularly if diagnosed late. According to different studies, between 10 and 80% of such carcinomas occur in a pre-existing or precancerous lesion. The World Health Organisation (WHO) recommends the use of two terms for such lesions: precursor lesions, i. Read More

View Article
February 2017
3 Reads

Erythroplasia of Queyrat treated with methyl aminolevulinate-photodynamic therapy (MAL-PDT): case report and review of the literature.

G Ital Dermatol Venereol 2016 Dec 1. Epub 2016 Dec 1.

Dermatology Unit "Daniele Innocenzi", Department of Medical and Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino, Terracina, Latina, Italy -

Erythroplasia of Queyrat (EQ) is a rare disease involving the mucosal and transitional surfaces of the penis. Effective treatment is necessary to minimize progression to squamous cell carcinoma. The standard therapy for EQ, partial or radical penectomy, is invasive; photodynamic therapy (PDT) may be an effective, non-surgical tissue-sparing option. Read More

View Article
December 2016
10 Reads

Zoon balanitis: A comprehensive review.

Indian J Sex Transm Dis AIDS 2016 Jul-Dec;37(2):129-138

Department of Dermatology, Venereology and Leprology, Pt. B D Sharma University of Health Sciences, Rohtak, Haryana, India.

The diagnosis and management of nonvenereal diseases are always a tough challenge for the dermatologist due to lack of studies on its diagnostic criteria and standard treatment guidelines. Zoon balanitis (ZB) is one of the benign nonvenereal dermatoses, which presents as a solitary, persistent erythematous plaque usually on the glans penis primarily in the uncircumcised, middle-aged to old-aged men. Although it was described by Zoon in 1952, its etiopathogenesis still remains hypothetical. Read More

View Article
November 2016
31 Reads

Dermoscopy in General Dermatology: A Practical Overview.

Dermatol Ther (Heidelb) 2016 Dec 9;6(4):471-507. Epub 2016 Sep 9.

Department of Experimental and Clinical Medicine, Institute of Dermatology, University of Udine, Udine, Italy.

Over the last few years, dermoscopy has been shown to be a useful tool in assisting the noninvasive diagnosis of various general dermatological disorders. In this article, we sought to provide an up-to-date practical overview on the use of dermoscopy in general dermatology by analysing the dermoscopic differential diagnosis of relatively common dermatological disorders grouped according to their clinical presentation, i.e. Read More

View Article
December 2016
46 Reads

[Dermatological diseases of the male genital tract].

Authors:
F-M Köhn

Hautarzt 2016 Oct;67(10):793-805

Andrologicum München, Burgstr. 7, 80331, München, Deutschland.

During complete inspection of skin a variety of penile skin alterations may be found. Not all dermatological findings have clinical relevance. Pearly papules and heterotopic sebaceous glands are physiological variations. Read More

View Article
October 2016
5 Reads

[Dermatological diseases of the external male genitalia : Part 2: Infectious and malignant dermatological].

Urologe A 2016 Jul;55(7):981-96

Gemeinschaftspraxis fur Dermatologie und Urologie, 35390, Gießen, Deutschland.

The urological and andrological examination of male patients should include inspection of the genital skin in order to detect malignant neoplasms, such as erythroplasia of Queyrat and infectious diseases, such as genital warts (condylomata acuminata). Independent of the incidental finding of relevant dermatological alterations in the genital area, sexually transmitted diseases such as syphilis must again be considered more often as the incidence has greatly increased in Germany during the last few years. In addition, urologists should be able to adequately advise patients on all aspects of diseases caused by human papillomavirus. Read More

View Article
July 2016
1 Read

Oral Cancer: An Evaluation of Knowledge and Awareness in Undergraduate Dental Students and the General Public.

Oral Health Prev Dent 2016;14(5):403-411

Purpose: To evaluate the knowledge of signs, symptoms and risk factors associated with oral cancer amongst undergraduate dental students and members of the general public.

Materials And Methods: This study was open for a period of six months (Jan-June, 2013) to all undergraduate dental students in the 4th and 5th year of the dental science programme and dental patients attending the School of Dentistry, Griffith University, Australia. The survey evaluated the knowledge and awareness of clinical signs and symptoms and risk factors of oral cancers. Read More

View Article
January 2017
2 Reads

Erythroplasia of Queyrat treated by laser and light modalities: a systematic review.

Lasers Med Sci 2016 Dec 21;31(9):1971-1976. Epub 2016 Jun 21.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, 1475 NW 12th Ave, Miami, FL, 33136, USA.

Erythroplasia of Queyrat (EOQ) is a squamous cell carcinoma in situ most commonly located on the glans penis or prepuce. EOQ accounts for roughly 10 % of all penile malignancies and may lead to invasive squamous cell carcinoma. Standard therapy includes local excision, partial or total penectomy, cryotherapy, and topical cytotoxic agents. Read More

View Article
December 2016
13 Reads

Prevalence and factors associated with oral potentially malignant disorders in Brazil's rural workers.

Oral Dis 2016 Sep 17;22(6):536-42. Epub 2016 May 17.

Health Collective Post-Graduate Program, Federal University of Rio Grande do Norte, Natal, RN, Brazil.

Objectives: To determine the prevalence of oral potentially malignant disorders (OPMDs) in a population of rural workers in the northeast of Brazil and to investigate the association with sociodemographic, occupational, and health factors.

Methods: A total of 1385 workers answered a validated questionnaire and were examined by calibrated dentists. A descriptive analysis, chi-square homogeneity test, and binary logistic regression were performed. Read More

View Article
September 2016
2 Reads

Potentially malignant oral lesions: clinicopathological correlations.

Einstein (Sao Paulo) 2016 Jan-Mar;14(1):35-40

Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.

Objective: To determine the incidence of potentially malignant oral lesions, and evaluate and correlate their clinical and pathological aspects.

Methods: The sample consisted of cases clinically diagnosed as oral leukoplakia, oral erythroplakia, erythroleukoplakia, actinic cheilitis, and oral lichen planus treated at a diagnostic center, between May 2012 and July 2013. Statistical tests were conducted adopting a significance level of 5% (p≤0. Read More

View Article
December 2016
3 Reads

Imiquimod in the treatment of penile intraepithelial neoplasia: An update.

Australas J Dermatol 2017 May 8;58(2):86-92. Epub 2016 Mar 8.

Department of Dermatology, Mater Misericordiae Hospital, Brisbane, Queensland, Australia.

Penile intraepithelial neoplasia (PIN), or penile squamous cell carcinoma in situ, is a rare disease and may be associated with high morbidity and mortality. In an attempt to avoid surgical intervention, which may result in poor cosmetic and functional outcomes for patients, many non-invasive treatments have been trialled with variable success rates. This review summarises the available literature describing the use of topical imiquimod for PIN. Read More

View Article
May 2017
3 Reads

Dermatoses of the Glans Penis in Korea: A 10-Year Single Center Experience.

Ann Dermatol 2016 Feb 28;28(1):40-4. Epub 2016 Jan 28.

Department of Dermatology, Pusan National University School of Medicine, Busan, Korea.; Medical Research Institute, Pusan National University Hospital, Busan, Korea.

Background: A variety of infectious, inflammatory, and neoplastic dermatoses can develop on the glans penis, and definitive diagnosis in such cases may be difficult owing to their non-specific symptoms and clinical appearance. Furthermore, data on dermatoses of the glans penis in Korea are limited.

Objective: In the present study, we aimed to determine the prevalence of dermatoses of the glans penis in Korea and provide clinical data to assist in making an accurate diagnosis. Read More

View Article
February 2016
12 Reads

Mouth Cancer for Clinicians Part 6: Potentially Malignant Disorders.

Dent Update 2015 Nov;42(9):866-8, 871-4, 877

Unlabelled: A MEDLINE search early in 2015 revealed more than 250,000 papers on head and neck cancer; over 100,000 on oral cancer; and over 60,000 on mouth cancer. Not all publications contain robust evidence. We endeavour to encapsulate the most important of the latest information and advances now employed in practice, in a form comprehensible to healthcare workers, patients and their carers. Read More

View Article
November 2015
2 Reads

Evaluation of confocal laser endomicroscopy as an aid to differentiate primary flat lesions of the larynx: A prospective clinical study.

Head Neck 2016 04 28;38 Suppl 1:E1695-704. Epub 2015 Nov 28.

Department of Otorhinolaryngology, Head and Neck Surgery, Klinikum der Universität München, Munich, Germany.

Background: In this trial, the ability of confocal laser endomicroscopy (CLE), a new imaging modality with a cellular resolution, to further differentiate primary flat lesions of the larynx was evaluated.

Methods: First, an optical coherence tomography was used to filter out normal tissue and carcinoma. All other lesions (30 lesions in 19 patients) were investigated with CLE. Read More

View Article
April 2016
2 Reads

Clinical characteristics of narrow-band imaging of oral erythroplakia and its correlation with pathology.

BMC Cancer 2015 May 15;15:406. Epub 2015 May 15.

Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung; No. 222, Mai Chin Road, Keelung, 204, Taiwan.

Background: To analyze the clinical application of endoscope with narrow-band imaging (NBI) system in detecting high-grade dysplasia, carcinoma in situ, and carcinoma in oral erythroplakia.

Methods: The demographic, histopathological data, and NBI vasculature architectures of patients receiving surgical intervention for oral erythroplakia were retrospectively reviewed and analyzed statistically.

Results: A total of 72 patients, including 66 males and 6 females, with mean age of 54. Read More

View Article

[Oral precancer and cancer].

Med Clin (Barc) 2015 Nov 29;145(9):404-8. Epub 2015 Jan 29.

Departamento de Odontoestomatología, Facultad de Odontología, Universidad de Barcelona, l'Hospitalet de Llobregat, Barcelona, España. Electronic address:

We reviewed the concept of oral precancerous lesions, oral cancer, and the possibility of early diagnosis. With the keywords: premalignant oral lesions prevention, a search was performed over the past 10 years. Also clinical trials are searched from January 2011 until today with the keywords: oral cancer prevention AND dentistry. Read More

View Article
November 2015
4 Reads

Clinicopathologic evaluation of lesions associated with tobacco usage.

J Contemp Dent Pract 2014 Jul 1;15(4):466-72. Epub 2014 Jul 1.

Private Practitioner, Guntur, Andhra Pradesh, India.

Introduction: Tobacco usage in different forms is the single most common etiological factor responsible for oral cancers. The aim of the present study was to record various mucosal lesions associated with tobacco usage and to ascertain the prevalence of dysplasia in them by histopathological evaluation and to compare the extent of dysplastic features seen among patients associated with a habit of smoked and smokeless form of tobacco.

Materials And Methods: Seventy-six patients with the clinical diagnosis of tobacco related lesions (Leukoplakia, Erythroplakia, Nicotina stomatitis, Tobacco pouch keratosis) were selected. Read More

View Article
July 2014
16 Reads

A case of erythroplasia of Queyrat successfully treated with combination carbon dioxide laser vaporization and surgery.

J Eur Acad Dermatol Venereol 2016 Mar 5;30(3):497-8. Epub 2014 Dec 5.

Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

View Article

Outcome of excision of oral erythroplakia.

Br J Oral Maxillofac Surg 2015 Feb 18;53(2):142-7. Epub 2014 Nov 18.

Department of Otolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan, ROC; School of Medicine, Chang Gung University College of Medicine, Taoyuan, Taiwan, ROC.

Oral erythroplakia is a precancerous lesion with high malignant potential, and resection is the recommended treatment. We designed a retrospective study to analyse the outcome of treatment in patients who had operations for oral erythroplakia. A total of 84 patients (74 men and 10 women, mean (SD) age 54 (12) years, range 29-83) were enrolled. Read More

View Article
February 2015
7 Reads

Clinical oral implications of human papillomavirus.

Authors:
Herbert Bader

Dent Today 2014 Aug;33(8):82-4; quiz 85

View Article
August 2014
2 Reads

The clinical effectiveness of reflectance optical spectroscopy for the in vivo diagnosis of oral lesions.

Int J Oral Sci 2014 Sep 25;6(3):162-7. Epub 2014 Jul 25.

Section of Oral Biology, Division of Oral Biology and Medicine, School of Dentistry, University of California at Los Angeles, Los Angeles, USA.

Optical spectroscopy devices are being developed and tested for the screening and diagnosis of oral precancer and cancer lesions. This study reports a device that uses white light for detection of suspicious lesions and green-amber light at 545 nm that detect tissue vascularity on patients with several suspicious oral lesions. The clinical grading of vascularity was compared to the histological grading of the biopsied lesions using specific biomarkers. Read More

View Article
September 2014
17 Reads

Queyrat erythroplasia accompanied by bladder cancer in a circumcised male.

Indian J Med Res 2014 Apr;139(4):650-1

Elazig Education and Research Hospital Dermatology Department, Elazig 23100, Turkey.

View Article
April 2014
2 Reads

Topical pharmacotherapy for skin cancer: part II. Clinical applications.

J Am Acad Dermatol 2014 Jun;70(6):979.e1-12; quiz 9912

Department of Dermatology, Rutgers University, New Jersey Medical School, Newark, New Jersey.

The purpose of the paper is to provide an in-depth, evidence-based analysis of the clinical use of topical treatments for skin cancer. A comprehensive review of topical drugs has been performed, including 5-fluorouracil, imiquimod, diclofenac, ingenol mebutate, retinoids, resiquimod, piroxicam, dobesilate, and betulinic acid. The evaluated studies were rated according to their level of evidence level (I-V), as indicated by recent guidelines for evidence-based medicine, The Oxford 2011 Levels of Evidence. Read More

View Article
June 2014
8 Reads

2013 European guideline for the management of balanoposthitis.

Int J STD AIDS 2014 Aug 14;25(9):615-26. Epub 2014 May 14.

Department of Dermatology, Havenziekenhuis, Rotterdam, The Netherlands.

Balanoposthitis can be caused by a disparate range of conditions affecting the penile skin. This guideline concentrates on a selected group of conditions and offers recommendations on the diagnostic tests and treatment regimens needed for the effective management of balanoposthitis. Read More

View Article
August 2014
12 Reads