3,186 results match your criteria Erythroderma Generalized Exfoliative Dermatitis


Adverse Drug Reactions Are the Main Causes of Erythroderma in an Argentinian Teaching Hospital: A Retrospective Study of 70 Patients.

Actas Dermosifiliogr 2022 Apr 29. Epub 2022 Apr 29.

Servicio de Dermatología, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Background: Erythroderma, characterized by erythema and scaling that affects at least 90% of the body, has diverse causes. Most of the clinical manifestations and laboratory findings are nonspecific, making diagnosis challenging.

Material And Methods: Retrospective study of patients treated between January 1, 2010, and June 1, 2020. Read More

View Article and Full-Text PDF

[A patient with erythroderma and pruritus: Sézary syndrome].

Ned Tijdschr Geneeskd 2022 02 16;166. Epub 2022 Feb 16.

Maasstad Ziekenhuis, afd. Interne Geneeskunde, Rotterdam.

Background: Erythroderma could be the first sign of a cutaneous T-cell lymphoma (CTCL), such as Sézary syndrome. Causes of erythroderma include inflammatory dermatosis, toxicoderma, paraneoplastic erytroderma, and CTCL. Hence, diagnosing Sézary syndrome can be difficult. Read More

View Article and Full-Text PDF
February 2022

Exfoliative Dermatitis as a Para-neoplastic Syndrome of Prostate Adenocarcinoma: A Rare Case Report With Literature Review.

Cancer Diagn Progn 2021 Sep-Oct;1(4):289-295. Epub 2021 Jul 3.

Department of Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX, U.S.A.

Background/aim: This study aimed to report a rare case of erythroderma or exfoliative dermatitis as a paraneoplastic syndrome of prostate adenocarcinoma. Exfoliative dermatitis is a rare inflammatory skin condition that is characterized by desquamation and erythema involving more than 90% of the body surface area. It is a clinical manifestation and usually associated with various underlying cutaneous disorders, drug induced reactions and malignancies. Read More

View Article and Full-Text PDF

Erythroderma: An unusual manifestation of imatinib - A rare case report.

J Cancer Res Ther 2022 Jan-Mar;18(1):253-256

Department of Medical Oncology and Hematology, GCRI, Ahmedabad, Gujarat, India.

Imatinib is a tyrosine kinase inhibitor that selectively inhibits several protein tyrosine kinases which is central to the pathogenesis of human cancer. It forms the first-line treatment for chronic myeloid leukemia (CML) and gastrointestinal stromal tumors. Usually, the drug is well-tolerated with relatively few side effects. Read More

View Article and Full-Text PDF

An Unusual Cytomegalovirus Ocular Manifestation in a Non-HIV Patient.

Cureus 2022 Feb 5;14(2):e21947. Epub 2022 Feb 5.

Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, MYS.

A 60-year-old Aboriginal man with underlying severe exfoliative dermatitis, treated with oral azathioprine and oral prednisolone, presented with left painful red eye for ten days. On initial presentation, left eye vision was poor at hand motion. There was corneal endotheliitis over the left eye with severe anterior chamber inflammation obscuring the fundus view. Read More

View Article and Full-Text PDF
February 2022

Severe cutaneous drug toxicity following enfortumab vedotin treatment for metastatic urothelial carcinoma.

JAAD Case Rep 2022 Mar 19;21:140-143. Epub 2022 Jan 19.

Department of Dermatology, Henry Ford Health System, Detroit, Michigan.

View Article and Full-Text PDF

Proposal for a 6-step approach for differential diagnosis of neonatal erythroderma.

J Eur Acad Dermatol Venereol 2022 Jul 15;36(7):973-986. Epub 2022 Mar 15.

Department of Dermatology, Center of Pediatric Dermatology, Erasmus MC University Medical Center Rotterdam-Sophia Children's Hospital, Rotterdam, The Netherlands.

The broad differential diagnosis of neonatal erythroderma often poses a diagnostic challenge. Mortality of neonatal erythroderma is high due to complications of the erythroderma itself and the occasionally severe and life-threatening underlying disease. Early correct recognition of the underlying cause leads to better treatment and prognosis. Read More

View Article and Full-Text PDF

Erythroderma in a neonate.

JAAD Case Rep 2022 Mar 19;21:97-100. Epub 2022 Jan 19.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida.

View Article and Full-Text PDF

Peeling Skin Syndrome Type 1: Dupilumab Reduces IgE, But Not Skin Anomalies.

J Clin Immunol 2022 May 23;42(4):873-875. Epub 2022 Feb 23.

Dermatology Department, Reference Center for Rare Skin Diseases, Paul Sabatier University, Larrey Hospital, 24 Chemin de Pouvourville, 31059 Cedex 09, Toulouse, France.

View Article and Full-Text PDF

A novel pathogenic variant in the corneodesmosin gene causing generalized inflammatory peeling skin syndrome with marked eosinophilia and trichorrhexis invaginata.

Pediatr Dermatol 2022 Mar 17;39(2):268-272. Epub 2022 Feb 17.

Department of Dermatology, Starship Children's Health, Auckland District Health Board, Auckland, New Zealand.

Generalized inflammatory peeling skin syndrome (PSS) is a rare autosomal recessive genodermatosis caused by loss-of-function disease-causing variants of the corneodesmosin gene (CDSN), resulting in excessive shedding of the superficial layers of the epidermis. We describe a case of generalized inflammatory PSS in an infant, presenting at day two of life with ichthyosiform erythroderma and superficial peeling of the skin. Hair microscopy showed trichorrhexis invaginata. Read More

View Article and Full-Text PDF

Sézary Syndrome: Different Erythroderma Morphological Features with Proposal for a Clinical Score System.

Cells 2022 01 20;11(3). Epub 2022 Jan 20.

Section of Dermatology, Department of Medical Sciences, University of Turin, 10126 Torino, Italy.

Sézary syndrome is a rare subtype of cutaneous T-cell lymphoma characterized by erythroderma, peripheral lymphadenopathies, and circulating atypical cerebriform T-cells. To date, no definite staging system has been developed for these patients. In this retrospective analysis of the archive of the Dermatological Clinic of the University of Turin, Italy, erythrodermic SS patients were classified according to clinical records and photographs into three main presentations: erythematous, infiltrated, or melanodermic. Read More

View Article and Full-Text PDF
January 2022

[Rash and erythroderma: identify and treat the cause].

Rev Prat 2021 Oct;71(8):922

Service de dermatologie, hôpital Saint-Louis, 75010 Paris, France.

View Article and Full-Text PDF
October 2021

[Exanthema and erythroderma in adults].

Rev Prat 2021 Oct;71(8):913-921

Service de dermatologie, hôpital Saint-Louis, 75010 Paris, France.

View Article and Full-Text PDF
October 2021

Erythroderma related with the first dose of Pfizer-BioNTech BNT16B2b2 COVID-19 mRNA vaccine in a patient with psoriasis.

Dermatol Ther 2022 May 14;35(5):e15363. Epub 2022 Feb 14.

School of Medicine, Department of Pathology, Hacettepe University, Ankara, Turkey.

View Article and Full-Text PDF

Etodolac-induced erythroderma.

Dermatol Online J 2021 Nov 15;27(11). Epub 2021 Nov 15.

Internal Medicine Department, Povoa de Varzim/Vila do Conde Hospitalar Centre, Povoa de Varzim, Portugal.

View Article and Full-Text PDF
November 2021

Novel splice mutation in CDSN gene causing type b peeling skin syndrome.

J Eur Acad Dermatol Venereol 2022 06 3;36(6):e456-e460. Epub 2022 Feb 3.

Department of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.

View Article and Full-Text PDF

Rapidly Progressive Erythroderma.

Am Fam Physician 2022 01;105(1):75-76

Largo Medical Center, Largo, FL, USA.

View Article and Full-Text PDF
January 2022

Clinical Patterns and Clinicopathologic Correlation of 100 Patients with Erythroderma in a Tertiary Care Institute in India.

Skinmed 2021 1;19(6):440-450. Epub 2021 Dec 1.

Department of Dermatology, Venereology & Leprology PGIMER, Chandigarh, India.

Erythroderma is a severe dermatologic manifestation of a variety of diseases. We analyzed the clinical parameters and the clinicopathologic correlation in patients with erythroderma. Consecutive patients diagnosed with erythroderma at a tertiary care institute were evaluated for 5 years. Read More

View Article and Full-Text PDF
January 2022

Neonatal inflammatory skin and bowel disease type 1 caused by a complex genetic defect and responsive to combined anti-tumour necrosis factor-α and interleukin-12/23 blockade.

Br J Dermatol 2022 Jun 19;186(6):1026-1029. Epub 2022 Apr 19.

Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.

ADAM17, encoding ADAM metallopeptidase domain 17, is a membrane-bound shedding protease, which plays an essential role during normal development and in the regulation of inflammation. Biallelic variants in ADAM17, resulting in complete loss of ADAM17 expression, have been reported in individuals affected by rare neonatal inflammatory skin and bowel disease 1 (NISBD1). Here, we report on a young female individual with NISBD1 featuring erythroderma, atrichia, nail dystrophy, oesophageal strictures, intractable diarrhoea, profound failure to thrive and recurrent cutaneous and systemic infections. Read More

View Article and Full-Text PDF

Erythroderma and Skin Desquamation in Paederus Dermatitis.

Case Rep Med 2021 28;2021:7257288. Epub 2021 Dec 28.

Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.

Exfoliative erythroderma is rare but serious condition, which requires close supervision. We report a rare case of 28-year-old man with kissing lesions of Paederus dermatitis at his right side of neck. The rash caused by beetle was improved after treatments. Read More

View Article and Full-Text PDF
December 2021

Dermatological adverse drug reactions of anticancer drugs: International data of pharmacovigilance: VigiBase®.

Therapie 2022 Mar-Apr;77(2):219-227. Epub 2021 Dec 11.

Service de pharmacologie médicale et clinique, CHU de Toulouse, 31000 Toulouse, France; Inserm, UMR1027, université Paul-Sabatier, 31000 Toulouse, France; Service de pharmacologie médicale et clinique, faculté de médecine, université Paul-Sabatier, 31000 Toulouse, France; Centre Midi-Pyrénées de pharmacovigilance, de pharmacoépidémiologie et d'informations sur le médicament, CHU de Toulouse, 31000 Toulouse, France; Inserm CIC 1436 Toulouse, centre d'investigation clinique de toulouse, CHU de Toulouse, 31000 Toulouse, France. Electronic address:

In the 2000s, newer generations of drugs appeared on the market called drugs of targeted therapy (TT) drugs. The introduction of TT in oncology has profoundly changed the prognosis of many cancers but also introduced a wide variety of adverse drugs reactions (ADR), including in particular dermatological adverse drug reactions (DADRs). We investigated the evolutions of the notifications of DADRs of anticancer drugs since 2000s in international pharmacovigilance data. Read More

View Article and Full-Text PDF

Prevalence of Metabolic Syndrome in Chinese Patients With Erythrodermic Psoriasis: A Case-Control Study.

Front Endocrinol (Lausanne) 2021 14;12:677912. Epub 2021 Dec 14.

Department of Dermatology, Huashan Hospital Affiliated with Fudan University, Shanghai, China.

Erythroderma psoriasis (EP) is a rare and severe form of psoriasis, which is a chronic inflammatory skin disease that usually occurs simultaneously with cardiovascular disease (CVD). Metabolic syndrome (MetS) is a significant precursor of CVD. This study was to investigate the association between EP and MetS in the Chinese population. Read More

View Article and Full-Text PDF
February 2022

Skin disease in goats (Capra aegagrus hircus): a retrospective study of 358 cases at a university veterinary teaching hospital (1988-2020).

Vet Dermatol 2022 Jun 27;33(3):227-e64. Epub 2021 Dec 27.

Department of Population Health & Reproduction, School of Veterinary Medicine, University of California, Davis, CA, 95616, USA.

Background: Goats are important worldwide as a source of milk, meat, fibre and hide, and as show animals and pets.

Hypothesis/objectives: To document the type, signalment associations and prevalence of skin disease in a referral hospital population.

Animals: Case population at a university veterinary teaching hospital. Read More

View Article and Full-Text PDF

Eosinophilic dermatosis in a patient with chronic lymphocytic leukemia: a rare case report.

Acta Dermatovenerol Alp Pannonica Adriat 2021 Dec;30(4):161-164

Hematological Laboratory, Second Department of Internal Medicine, Aristotle University, Hippokration Hospital, Thessaloniki, Greece.

Chronic lymphocytic leukemia (CLL) is a type of malignant lymphoproliferative disorder characterized by a rapid and uncontrolled increase in lymphoid cells, mostly monoclonal B-cells (B-CLL). Patients with CLL may present cutaneous lesions that can be classified as either "specific" or "non-specific." In CLL patients, specific skin eruptions arise from leukemic cell infiltration, recognized histopathologically in tissue sample biopsy. Read More

View Article and Full-Text PDF
December 2021

Erythroderma secondary to crusted scabies.

BMJ Case Rep 2021 Dec 14;14(12). Epub 2021 Dec 14.

Department of Dermatology, Venereology & Leprsoy, All India Institute of Medical Sciences, Rishikesh, Rishikesh, Uttarakhand, India

View Article and Full-Text PDF
December 2021

Omenn Syndrome due to RAG1 Mutation Presenting With Nonimmune Hydrops Fetalis in Two Siblings.

Pediatrics 2022 01;149(1)

Neonatology Unit, Mother-Child Department, University Hospital of Modena, Modena, Italy.

Omenn syndrome (OS) is a rare variant of severe combined immunodeficiency characterized by susceptibility to severe opportunistic infections and peculiar manifestations, such as protein-losing erythroderma, alopecia, hepatosplenomegaly, lymphadenopathies, and severe diarrhea. The typical form of the disease is caused by hypomorphic mutation of the recombination-activating genes (RAG1 and RAG2), which are critical in initiating the molecular processes leading to lymphocyte and immunoglobulin receptor formation. Affected patients lack B cells, whereas autoreactive oligoclonal T cells infiltrate the skin, gut, spleen, and liver. Read More

View Article and Full-Text PDF
January 2022

Prenatal ultrasound diagnostic approach to Omenn syndrome: case report

Rev Colomb Obstet Ginecol 2021 09 30;72(3):291-297. Epub 2021 Sep 30.

Universidad El Bosque, Bogotá (Colombia). .

Objective: To report the case of a pregnant woman with ultrasound diagnosis of altered fetal tegumental system and postnatal diagnosis of Omenn syndrome.

Case Presentation: A 27-year-old patient who presented at 31 weeks of gestation with prenatal ultrasound evidence of a fetus with significant scalp edema, echogenic amniotic fluid and scaly abdominal skin, with ichtyosis variant impression on diagnostic ultrasound. The baby was born with congenital erythroderma complicated with skin infection, and later developed septic shock and died. Read More

View Article and Full-Text PDF
September 2021

Generalized dermatophytosis caused by in 8 juvenile black bears in California.

J Vet Diagn Invest 2022 Mar 28;34(2):279-283. Epub 2021 Nov 28.

California Animal Health and Food Safety Laboratory System, University of California-Davis, CA, USA.

From 2014-2019, 8 juvenile black bears () from different geographic regions were presented to the California Department of Fish and Wildlife because of emaciation, alopecia, and exfoliative dermatitis that resulted in death or euthanasia. Autopsy and histopathology revealed that all 8 bears had generalized hyperkeratotic dermatitis, folliculitis, and furunculosis. Skin structures were heavily colonized by fungal hyphae and arthrospores; fungal cultures of skin from 7 bears yielded , a zoophilic dermatophyte reported only rarely in non-equid species. Read More

View Article and Full-Text PDF