4,476 results match your criteria Erythroderma Generalized Exfoliative Dermatitis


Novel ABCA12 compound heterozygous mutations identified in a patient with congenital ichthyosiform erythroderma and aortopulmonary window.

Eur J Dermatol 2018 Dec 10. Epub 2018 Dec 10.

Department of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, China.

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December 2018

Sezary syndrome, recent biomarkers and new drugs.

Chin Clin Oncol 2018 Nov 28. Epub 2018 Nov 28.

Istituto Dermopatico dell' Immacolata, IDI-IRCCS, Rome, Italy.

Sezary syndrome (SS) is a primary cutaneous T-cell lymphoma (CTCL) characterized by erythroderma, lymphadenopathy and leukemic involvement of the peripheral blood. The high relapse rates and a poor prognosis complicate its clinical course and treatment. The phenotypic characterization and genomic/transcriptomic approaches revealed high heterogeneity of Sezary cells, identifying a wide spectrum of biomarkers implicated in the development of this lymphoma. Read More

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November 2018

Update on skin directed therapies in mycosis fungoides.

Chin Clin Oncol 2018 Nov 28. Epub 2018 Nov 28.

Department of Dermatology, University Hospital Birmingham, Birmingham, UK.

Mycosis fungoides (MF) represents the majority of the primary cutaneous T-cell lymphomas (CTCL). Most have early stage MF with localised patches and plaques, which has a favourable survival outcome, but nearly a quarter progress to late stage with tumours, erythroderma, and systemic involvement. Management is based on stage directed treatment with early stage MF (IA-IIA) using skin directed therapies (SDTs), including topical corticosteroids (TCS), chlormethine or retinoids, phototherapy, and radiotherapy (localised or total skin electron beam therapy). Read More

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November 2018

Case of pityriasis rubra pilaris progressed to generalized erythroderma following blockade of interleukin-17A, but improved after blockade of interleukin-12/23 p40.

J Dermatol 2018 Dec 3. Epub 2018 Dec 3.

Department of Dermatology, Kansai Medical University, Hirakata, Japan.

We report herein a case of a 72-year-old man with pityriasis rubra pilaris (PRP) that was refractory to conventional therapies. His skin lesions progressed to generalized erythroderma despite anti-interleukin (IL)-17A antibody therapy. Topical corticosteroids, emollients, systemic retinoid, methotrexate, cyclosporin and phototherapy yielded no therapeutic response. Read More

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December 2018
6 Reads

Differential Diagnosis of Cheilitis - How to Classify Cheilitis?

Acta Clin Croat 2018 Jun;57(2):342-351

Department of Dermatovenereology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia.

Although cheilitis as a term describing lip inflammation has been identified and recognized for a long time, until now there have been no clear recommendations for its work-up and classification. The disease may appear as an isolated condition or as part of certain systemic diseases/conditions (such as anemia due to vitamin B12 or iron deficiency) or local infections (e.g. Read More

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June 2018
7 Reads

Sézary syndrome without erythroderma: A case report and review of published work.

J Dermatol 2018 Oct 31. Epub 2018 Oct 31.

Department of Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan.

Sézary syndrome (SS) is defined by erythroderma and circulating atypical T cells, with or without lymphadenopathy. Recently, Thompson et al. identified a distinct population of SS patients with an atypical presentation: a high blood tumor burden of Sézary cells fulfilling criteria for SS but without fulfilling the criteria for erythroderma at the diagnosis. Read More

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October 2018
7 Reads

Targeted killing of TNFR2-expressing tumor cells and T by TNFR2 antagonistic antibodies in advanced Sézary syndrome.

Leukemia 2018 Oct 24. Epub 2018 Oct 24.

Massachusetts General Hospital and Harvard Medical School, Building 149, 13th Street, Rm 3602, 02129, Boston, MA, USA.

Sézary syndrome (SS) is a rare form of cutaneous T-cell lymphoma often refractory to treatment. SS is defined as adenopathy, erythroderma with high numbers of atypical T cells. This offers an opportunity for new interventions and perhaps antibody-based therapeutic by virtue of its high expression of the TNFR2 oncogene on the tumor cells and on T-regulatory cells (T). Read More

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October 2018
15 Reads

Phototherapy of cutaneous T-cell lymphomas.

Authors:
Franz Trautinger

Photochem Photobiol Sci 2018 Dec;17(12):1904-1912

Department of Dermatology and Venereology, Karl Landsteiner University of Health Sciences, University Hospital of St. Pölten, Austria.

Cutaneous T-cell lymphomas (CTCL) are a heterogenous group of non-Hodgkin lymphomas arising in the skin. Mycosis fungoides (MF), the most common variant, is characterised by clonal proliferation of skin residing malignant T-cells. Initially appearing with erythematous patches and plaques it follows a chronic course with progression to cutaneous tumours and extracutaneous involvement in some patients. Read More

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December 2018
6 Reads

Excessive hair growth in a patient with psoriatic erythroderma following secukinumab administration.

Eur J Dermatol 2018 Aug;28(4):539-540

Department of Dermatology, University of Occupational and Environmental Health, 1-1 Iseigaoka, Yahatanishi-ku, Kitakyushu 807-8555, Japan.

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August 2018
11 Reads

A Practical Approach to the Diagnosis and Treatment of Adult Erythroderma.

Actas Dermosifiliogr 2018 Nov 10;109(9):777-790. Epub 2018 Oct 10.

Departamento de Dermatología, Universidad Autónoma de Nuevo León, Hospital Universitario «Dr. José E. González» y Facultad de Medicina, Monterrey, México. Electronic address:

Erythroderma is an inflammatory skin syndrome that involves desquamation and erythema of more than 90% of the body surface area. It represents a final clinical endpoint for many adult dermatological conditions. The most frequent cause of erythroderma is psoriasis followed by eczematous conditions, drug-induced reactions, pityriasis rubra pilaris and cutaneous T-cell lymphomas. Read More

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November 2018
12 Reads

Amoxicillin/clavulanic acid-induced exfoliative dermatitis in a child.

Minerva Pediatr 2018 Oct;70(5):495-496

Allergy Unit, Department of Pediatrics, Anna Meyer Children's University Hospital, Florence, Italy.

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October 2018
41 Reads

Novel and recurrent mutations in keratin 1 cause epidermolytic ichthyosis and palmoplantar keratoderma.

Clin Exp Dermatol 2018 Oct 4. Epub 2018 Oct 4.

Alan Lyell Centre for Dermatology, Queen Elizabeth University Hospital, Glasgow, UK.

Mutations in keratin genes underlie a variety of epidermal and nonepidermal cell-fragility disorders, and are the genetic basis of many inherited palmoplantar keratodermas (PPKs). Epidermolytic PPK (EPPK) is an autosomal dominant disorder that can be due to mutations in the keratin 1 gene, KRT1. Epidermolytic ichthyosis (EI), the major keratinopathic ichthyosis, is characterized by congenital erythroderma, blistering and erosions of the skin. Read More

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October 2018
5 Reads

A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics.

J Am Acad Dermatol 2018 Oct 1. Epub 2018 Oct 1.

Department of Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois; Northwestern Medicine Multidisciplinary Eczema Center, Chicago, Illinois. Electronic address:

Background: Previous studies found conflicting results about the commonality of different atopic dermatitis (AD) signs and symptoms.

Objective: To determine the prevalences of AD characteristics and differences by region and age.

Methods: A systematic review was performed of all published studies in MEDLINE, EMBASE, SCOPUS, LILACS, Cochrane, China National Knowledge Infrastructure, Taiwan Electronic Periodical Services, and CiNii that analyzed the proportion of AD characteristics. Read More

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October 2018
1 Read

Netherton Syndrome: A Case Report and Review of Literature.

Cureus 2018 Jul 30;10(7):e3070. Epub 2018 Jul 30.

Internal Medicine, Icahn School of Medicine at Mount Sinai Queens Hospital Center, New York, USA.

Netherton syndrome (NS) is a rare autosomal recessive disorder characterized by a triad of congenital ichthyosiform erythroderma (CIE) or ichthyosis linearis circumflexa (ILC), hair shaft abnormalities, and atopic diathesis (elevated serum IgE ). We report a case of a two-year-old boy presented with intractable pruritus, scaling, dry skin and generalized eczematous lesions resistant to atopic dermatitis therapy. Netherton syndrome misdiagnosed as atopic dermatitis due to the presence of eczematous skin lesions and allergic problems. Read More

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July 2018
6 Reads

Profile of erythroderma in children in hospital dermatology departments in Lomé, Togo : study of 28 cases.

Med Sante Trop 2018 Aug;28(3):277-279

Service dermatologie et IST, CHU Sylvanus Olympio, Université de Lomé, 14BP 200 Lomé, Togo.

The aim of this study was to describe the epidemiological, clinical, and therapeutic profile as well as the outcomes of children with erythroderma (also known as exfoliative dermatitis) in hospital dermatology departments in Lomé, Togo. This retrospective descriptive study examined the records of patients aged 0 to 15 years who were treated for erythroderma in dermatology departments in Lomé from January 1997 to December 2016. The study included 28 patients, with a mean age of 6. Read More

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Dramatic response to brentuximab vedotin in a refractory non-transformed CD30-negative mycosis fungoides allowing allogeneic stem cells transplantation and long-term complete remission.

Br J Dermatol 2018 Sep 30. Epub 2018 Sep 30.

Dermatology Department, AP-HP Hôpital Saint-Louis, Paris.

The erythrodermic ulcerated form of mycosis fungoides (MF) is exceptional, and treatment of refractory cases is therefore very challenging. Brentuximab Vedotin (BV) is a monoclonal antibody combined with monomethyl auristatin E, recently approved for the treatment of refractory cutaneous T-cell lymphoma with CD30 expression. We report in this article a case of refractory MF in a 56 year-old man with a long story of large plaque parapsoriasis, as revealed by a psoriasiform erythroderma, treated initially with CHOP (cyclophosphamide, doxorubicine, vincristine and prednisone) polychemotherapy inducing a two year complete response. Read More

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September 2018
5 Reads

Results of a nationwide epidemiologic survey of autosomal recessive congenital ichthyosis and ichthyosis syndromes in Japan.

J Am Acad Dermatol 2018 Sep 26. Epub 2018 Sep 26.

Department of Dermatology and Allergology, Juntendo University Graduate School of Medicine, Tokyo, Japan.

Background: Autosomal recessive congenital ichthyosis (ARCI) and ichthyosis syndrome (IS) are rare genetic skin disorders.

Objective: To estimate the number of patients with ARCI and IS in Japan and clarify the clinicoepidemiologic features of these diseases.

Methods: We performed a nationwide survey of patients treated for ARCI or IS during January 2005-December 2009. Read More

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September 2018
16 Reads

A clinical case of severe disease burden: an erythrodermic psoriatic patient treated with secukinumab.

J Dermatolog Treat 2018 Sep 26:1-11. Epub 2018 Sep 26.

a Department of Dermatology , University of Rome "Tor Vergata" , Viale Oxford 81 , 00133 Rome , Italy.

Erythrodermic psoriasis is a severe variant of psoriasis characterized by prominent erythema, affecting the entire body surface. Management of erythrodermic psoriasis is difficult, not standardized, and often ineffective. As clinical studies are lacking, reporting of clinical experience with secukinumab may help to gather insight in this field. Read More

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September 2018

A severe case of bevacizumab-induced thrombotic microangiopathy.

J Oncol Pharm Pract 2018 Sep 26:1078155218800371. Epub 2018 Sep 26.

2 Department of Medical Oncology, Istanbul University Cerrahpaşa Medical Faculty Hospital, Istanbul, Turkey.

Bevacizumab is a human monoclonal antibody against VEGF. Many adverse reactions about bevacizumab are identified including venous and arterial thromboembolism, nausea, fatigue, alopecia, proteinuria, gastrointestinal system (GIS) perforation, exfoliative dermatitis, and peripheral edema and thrombocytopenia. In this paper, we report a case of bevacizumab-induced dose-dependent, toxicity-mediated drug-induced thrombotic microangiopathy. Read More

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September 2018
1 Read

Management of fluid status and cardiovascular function in patients with diffuse skin inflammation.

J Dermatolog Treat 2018 Nov 19:1-5. Epub 2018 Nov 19.

e Department of Pulmonary and Critical Care, Wake Forest School of Medicine , Winston-Salem , NC , USA.

Background: Skin inflammation causes vasodilation and increased vascular permeability, which may result in decreased blood pressure and peripheral edema. Patients with erythroderma usually compensate for low blood pressure with fluid retention and increased cardiac output. However, if the heart cannot support increased cardiac output, blood pressure will stay low, resulting in severe compensatory fluid retention, which leads to decompensated congestive heart failure, and pulmonary edema. Read More

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November 2018
10 Reads

Erythroderma: A Rare Complication of Dyshidrotic Eczema.

Cureus 2018 Jul 19;10(7):e3005. Epub 2018 Jul 19.

Department of Dermatology, Creighton University School of Medicine, Omaha, USA.

A 47-year-old man with a history of dyshidrotic eczema presented to the emergency department with diffuse erythema, chills and pruritus of three weeks' duration. The patient had received two injections of methotrexate in the preceding two weeks, both of which had failed to improve his whole-body erythema and pruritus. In the emergency department, the patient was evaluated for infection and admitted for the dermatology consultation. Read More

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July 2018
2 Reads

Clinical and histopathological spectrum of toxic erythema of chemotherapy in patients who have undergone allogeneic hematopoietic cell transplantation.

Hematol Oncol Stem Cell Ther 2018 Sep 20. Epub 2018 Sep 20.

Department of Dermatology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Objective/background: Toxic erythema of chemotherapy (TEC) is a well-recognized adverse cutaneous reaction to chemotherapy. Similar to many skin diseases, the clinical presentations may vary. Our objective is to expand on the typical and atypical clinical and histopathological presentations of TEC. Read More

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September 2018
2 Reads

Metastatic pulmonary melanoma complicated with erythroderma and recurrent sepsis.

Respir Med Case Rep 2018 10;25:204-206. Epub 2018 Sep 10.

Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Erythroderma is occasionally associated with lung cancer. Here we report a 69-year-old male who has history of melanoma from 8 years ago presented with erythroderma associated with skin, soft tissue and pulmonary infection. CT chest showed a single enlarging right upper lobe lung nodule. Read More

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September 2018

Langerhans Cell Histiocytosis with Lymph Node Involvment Presenting as Erythroderma.

Acta Derm Venereol 2018 Sep 5. Epub 2018 Sep 5.

Department of Dermatology, The Second Hospital of Dalian Medical University, Dalian 116027, China.

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September 2018
8 Reads

Bullous erythroderma: novel association of pityriasis rubra pilaris with bullous pemphigoid.

Clin Exp Dermatol 2019 01 20;44(1):73-75. Epub 2018 Aug 20.

Dermatology Unit, Department of Physiopathology and Transplantation, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Pace 9, 20122, Milan, Italy.

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January 2019

Erythrodermic presentation of psoriasis in a patient treated with dupilumab.

JAAD Case Rep 2018 Aug 15;4(7):708-710. Epub 2018 Aug 15.

Department of Dermatology, Cleveland Clinic, Cleveland, Ohio.

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Pityriasis rubra pilaris-like erythroderma in the setting of pembrolizumab therapy responsive to acitretin.

JAAD Case Rep 2018 Aug 9;4(7):669-671. Epub 2018 Aug 9.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.

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August 2018
1 Read

Generation, Characteristics and Clinical Trials of Ex Vivo Generated Tolerogenic Dendritic Cells.

Yonsei Med J 2018 Sep;59(7):807-815

College of Pharmacy, Chungbuk National University, Cheongju, Korea.

Dendritic cells (DCs) play a key role not only in the initiation of primary immune responses, but also in the development and maintenance of immune tolerance. Numerous protocols have been developed to generate tolerogenic DCs (tolDCs) ex vivo, and the therapeutic efficacy of ex vivo-generated tolDCs has been demonstrated in autoimmune disease animal models. Based on successes in small animal models, several clinical trials have been completed or are on-going in patients with autoimmune diseases such as rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and Crohn's disease. Read More

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September 2018
5 Reads

Collodion baby case series: the success of oral retinoic acid.

Turk Pediatri Ars 2018 Mar 1;53(1):51-56. Epub 2018 Mar 1.

Mersin Women's and Children's Hospital, Neonatal Intensive Care Unit, Mersin, Turkey.

Ichthyosis is a clinical skin cornification disorder characterized by hyperkeratosis. Lamellar ichthyosis is a rare form of ichthyosis (collodion baby), which is autosomal recessive. Diagnostic clinical findings can be confirmed with skin biopsy and genetic analysis. Read More

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Wet wrap dressings as a rescue therapy option for erythrodermic psoriasis.

An Bras Dermatol 2018 Jul-Aug;93(4):598-600

Dermatology Service, Hospital Santa Casa de Curitiba, Curitiba (PR), Brazil.

Wet wrap dressings provide an ancillary treatment option for erythrodermic patients. Wet wrap therapy consists of the application of topical corticosteroids on all affected surfaces, followed by the application of a warm moist cotton cloth with a dry cotton cloth on top. The advantages of this procedure include its safety, as well as the prompt and marked improvement of the erythroderma. Read More

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September 2018
6 Reads

Dapsone Hypersensitivity Syndrome (Dhs): A Detrimental Effect Of Dapsone? A Case Report.

Curr Drug Saf 2018 Jul 31. Epub 2018 Jul 31.

Department of Pharmacy Practice, Aashiq Ahamed Shukkoor, PSG College of Pharmacy, Coimbatore, Tamilnadu. India.

Dapsone is a sulfone derived drug used in the treatment of leprosy and several chronic inflammatory dermatological diseases. Dapsone hypersensitivity syndrome (DHS) is characterized by fever, hepatitis, generalized exfoliative dermatitis and lymphadenopathy. It is rare and potentially fatal. Read More

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July 2018
12 Reads

[Role of intercellular slit-like contacts (connexins) in the pathogenesis of erythroderma].

Arkh Patol 2018;80(4):61-64

Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia, Saint Petersburg, Russia.

Erythroderma is a skin lesion characterized by redness, swelling, infiltration, and desquamation of greater than 90% of the skin. The etiology of erythroderma is not completely clear and the lesion can be manifestations of various chronic dermatoses, including atopic dermatitis, psoriasis, eczema, and toxicodermia, and be represented by erythrodermic mycosis fungoides. The pathogenesis of erythroderma especially at the genetic level remains little studied. Read More

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January 2018

Hydroxychloroquine-Induced Psoriasis-form Erythroderma in a Patient with Systemic Lupus Erythematosus.

Chin Med J (Engl) 2018 Aug;131(15):1887-1888

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

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August 2018
2 Reads

Pityriasis Rubra Pilaris With Extensive Follicular Acantholysis Resembling Pemphigus Vulgaris: A Case Report.

Am J Dermatopathol 2018 Jul 24. Epub 2018 Jul 24.

Department of Pathology and Laboratory Medicine, Dartmouth-Hitchcock Medical Center and Geisel School of Medicine, Lebanon, NH.

Pityriasis rubra pilaris (PRP) is a rare, chronic, heterogeneous, papulosquamous inflammatory dermatosis of unknown etiology. Although erythematous scaly patches characterize the classic presentation of PRP, a broad range of clinical presentations has been reported. Histologically, PRP is characterized by psoriasiform acanthosis with alternating orthokeratosis and parakeratosis and rarely small acantholytic foci. Read More

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July 2018
16 Reads

A successful case of neoadjuvant chemotherapy and radical hysterectomy during pregnancy for advanced uterine cervical cancer accompanied by neonatal erythroderma.

J Obstet Gynaecol Res 2018 Oct 25;44(10):2003-2007. Epub 2018 Jul 25.

Department of Obstetrics and Gynecology, Kanazawa University, Kanazawa, Ishikawa, Japan.

Recent reports showed that neoadjuvant chemotherapy (NAC) has been successfully applied to treat advanced uterine cervical cancers during pregnancy. However, its side effects on the fetus remain unclear. Here, we report a 33-year-old primipara who underwent four courses of NAC therapy, paclitaxel and cisplatin, from 17 to 27 weeks of gestation due to uterine cervical cancer stage IB2. Read More

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October 2018
6 Reads

Netherton syndrome: A neonatal case with respiratory insufficiency.

Arch Argent Pediatr 2018 Aug;116(4):e609-e611

Department of Pediatrics, Division of Neonatology, Ankara University, Faculty of Medicine, Ankara, Turkey.

Netherton syndrome (NS) is a rare, autosomal recessive disease characterized with congenital ichthyosiform erythroderma, hair abnormality and atopic manifestations. This syndrome is caused by recessive mutation in the SPINK5 gene. Disease manifestations vary considerably among NS individuals. Read More

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August 2018
1 Read

Hypersensitivity to orthopaedic implant manifested as erythroderma: Timing of implant removal.

Int J Surg Case Rep 2018 23;49:110-114. Epub 2018 Jun 23.

Rumah Sakit Orthopaedi Purwokerto, Purwokerto, Indonesia. Electronic address:

Introduction: Incidence of hypersensitivity to orthopaedic implant, once estimated in less than 1% of population, recently has increased to 10%. Controversies about the timing of implant removal remain, especially due to the fact that implant hypersensitivity may be a contributing factor to implant failure. We present a case report and literature reviews to establish the decision making for the timing of implant removal in the presence of implant hypersensitivity. Read More

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June 2018
4 Reads

Recent advances in understanding inherited disorders of keratinization.

F1000Res 2018 27;7. Epub 2018 Jun 27.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut, USA.

The ichthyoses are a heterogeneous group of skin diseases characterized by localized or generalized scaling or both. Other common manifestations include palmoplantar keratoderma, erythroderma, recurrent infections, and hypohidrosis. Abnormal barrier function is a cardinal feature of the ichthyoses, which results in compensatory hyperproliferation and transepidermal water loss. Read More

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Meeting a rare disease: a case of bullous ichthyosiform erythroderma.

G Ital Dermatol Venereol 2018 Jul 10. Epub 2018 Jul 10.

Department of Dermatology, Division of Medical, Surgical and Neurosciences, University of Siena, Siena, Italy.

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July 2018
9 Reads

Dermatology emergencies: handy hints for the acute medical team.

Br J Hosp Med (Lond) 2018 Jul;79(7):378-383

Dermatology Consultant, Department of Dermatology, Salford Royal NHS Foundation Trust, Salford.

This article will help the general physician recognize and manage acute dermatology presentations. This can be challenging for non-dermatology doctors owing partly to the difficulty in providing an extensive dermatology undergraduate education and the lack of exposure to dermatology patients. The problem is further compounded at many hospital trusts because of the lack of on-site dermatology 'on-call'. Read More

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July 2018
1 Read

Exfoliative Cheilitis as a Manifestation of Factitial Cheilitis.

Cureus 2018 May 2;10(5):e2565. Epub 2018 May 2.

Department of Oral and Maxillofacial Pathology, San Antonio Military Medical Center.

Factitial cheilitis is a rare diagnosis of exclusion that occurs most frequently in young women with a history of anxiety disorders and recent psychosocial stressors. It presents as continuous keratinaceous build-up, crusting, and desquamation of the lips, consistent with exfoliative cheilitis. Affected areas can progress to superinfection with Staphylococcus aureus or Candida albicans. Read More

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May 2018
9 Reads

Juvenile Open Angle Glaucoma With Nonbullous Congenital Ichthyosiform Erythroderma.

J Glaucoma 2018 Nov;27(11):e180-e182

Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA.

Introduction: Glaucoma in patients with nonbullous congenital ichthyosiform erythroderma (NBCIE) is a rare entity that has not been described in a histologically confirmed case. We present a unique case of coexisting glaucoma, ichthyosis, and dwarfism that has not been previously described.

Methods: We present a case of NBCIE with glaucoma and dwarfism that presented to our outpatient department. Read More

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November 2018
2.430 Impact Factor

The Coexistence of Systemic Lupus Erythematosus and Psoriasis: Is It Possible?

Acta Med Indones 2018 Apr;50(2):144-150

Department of Internal Medicine, Faculty of Medicine, Airlanggan University - dr. Soetomo Hospital, Surabaya, Indonesia.

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with various clinical disorders and frequent exacerbations. Psoriasis vulgaris is a common skin disorder which affect 1-3% of general populations. The pathophysiology regarding the coexistence of these diseases is not fully understood. Read More

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April 2018
3 Reads

Sézary Syndrome Presenting With Renal Involvement.

Am J Kidney Dis 2018 Dec 22;72(6):890-894. Epub 2018 Jun 22.

John Walls Renal Unit, University Hospitals of Leicester NHS Trust, Leicester, United Kingdom; Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, United Kingdom.

Sézary syndrome is a rare aggressive leukemic variant of primary cutaneous T-cell lymphoma, typically presenting with erythroderma, lymphadenopathy, and an atypical clonal T-cell population. Though it often involves the spleen and liver, we report a case of Sézary syndrome with renal involvement that was treated successfully. Visceral involvement confers a poor prognosis requiring systemic treatment. Read More

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December 2018
13 Reads

Identification and association of recurrent ALOXE3 mutation with non-bullous congenital ichthyosiform erythroderma in two ethnically distinct Pakistani families.

Congenit Anom (Kyoto) 2018 Jun 23. Epub 2018 Jun 23.

Institute of Biomedical and Genetic Engineering, Islamabad, Pakistan.

Non-bullous congenital ichthyosiform erythroderma (NCIE) is characterized by skin scaling with erythema. In this study, two Pakistani families with NCIE are genetically characterized through Whole Exome and Sanger sequencing to identify molecular basis of the disease. We identified a nonsense homozygous c. Read More

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June 2018
7 Reads
0.783 Impact Factor

Case for diagnosis. Erythroderma as manifestation of hypereosinophilic syndrome.

An Bras Dermatol 2018 Jun;93(3):451-453

Department of Dermatology, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brazil.

Hypereosinophilic syndrome is defined as persistent eosinophilia (>1500/µL for more than six months) associated with organ involvement, excluding secondary causes. It is a rare, potentially lethal disease that should be considered in cutaneous conditions associated with hypereosinophilia. We report a case of erythroderma as a manifestation of hypereosinophilic syndrome. Read More

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June 2018
3 Reads

Erythrodermic psoriasis and human immunodeficiency virus: association and therapeutic challenges.

An Bras Dermatol 2018 Jun;93(3):438-440

School of Medicine, Faculty of Medicine, University of Chile, Santiago, Chile.

Erythrodermic psoriasis is a rare but severe type of psoriasis that may be triggered by human immunodeficiency virus infection. We describe the case of a 65-year-old male patient with chronic psoriasis who presents an exacerbation of his condition over a period of two weeks. Because of the severity of his case and subsequent need for systemic therapy, human immunodeficiency virus enzyme immunoassay was performed and tested positive. Read More

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June 2018
4 Reads