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    7691 results match your criteria Erythema Multiforme

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    [A case of Orf disease complicated by erythema multiforme].
    Arch Pediatr 2017 Nov 16. Epub 2017 Nov 16.
    Service d'accueil des urgences, American Memorial Hospital, CHU de Reims, 47, rue Cognacq-Jay, 51100 Reims, France.
    Ecthyma contagiosum, or Orf, is a specific infection of small ruminants accidentally reaching humans. Few cases have been reported in the literature to date. We report here a case of ecthyma contagiosum occurred in a 9-year-old girl after contact with a flock of ecthyma sheep. Read More

    Milker's nodule:an occupational infection and threat to the immunocompromised.
    J Eur Acad Dermatol Venereol 2017 Nov 10. Epub 2017 Nov 10.
    Dermatology Department, New Jersey Medical School, Rutgers University School of Public Affairs and Administration, Newark, NJ, USA.
    Milker's nodule virus, also called paravaccinia virus is a DNA virus of the parapoxvirus genus transmitted from infected cows to humans. It results from contact with cattle, cattle byproducts, or fomites. Classified as an occupational disorder, those at risk of exposure include farmers, butchers, and agricultural tourists. Read More

    Polymorphous Light Eruption.
    Adv Exp Med Biol 2017 ;996:61-70
    University of Genoa, Genoa, Italy.
    Polymorphous light eruption (PLE) is the commonest immuno-mediated photodermatosis. It occurs after solar or artificial UV-light exposure and affects only the sun-exposed areas with preference of the V-area of the chest, of arms and forearms, legs, upper part of the back, and rarely the face. The lesions are itching or burning, and vary morphologically from erythema to papules, vesico-papules and occasionally blisters, plaques, sometimes erythema multiforme-like, insect bite-like wheals and purpura. Read More

    Multi-system manifestations of Mycoplasma pneumoniae infection in a young patient.
    JMM Case Rep 2017 Sep 19;4(9):e005117. Epub 2017 Sep 19.
    Infectious Diseases Unit, Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman.
    Introduction.Mycoplasma pneumoniae is a small cell-wall-lacking bacterium that belongs to the mycoplasma (Mollicutes) prokaryote micro-organisms. It is a common cause of both upper and lower respiratory tract infections in all age groups. Read More

    [Acute hemorrhagic edema of infancy: alarming lesions of a benign condition. Case report].
    Arch Argent Pediatr 2017 12;115(6):e432-e435
    Salud total EPS, Urbanización El Bosque.
    We report a case of acute hemorrhagic edema of infancy in an 18-month-old boy after an episode of otitis media. The clinical presentation begins with skin erythematous macules on the thighs, followed by purpuric lesions in arms, legs, and ankle edema. It was initially interpreted as urticaria, whereby steroids were indicated. Read More

    Autoimmune Progesterone Dermatitis: A Diagnosis to Consider in a Patient With Cyclical Cutaneous Eruptions.
    J Drugs Dermatol 2017 Oct;16(10):1040-1042
    Autoimmune progesterone dermatitis (APD) is a cyclical cutaneous reaction to progesterone, with symptoms that typically begin 3-10 days before the onset of menstrual flow and end 1-2 days into menses. The symptoms vary in severity from barely visible to anaphylaxis, but most often include an eczematous eruption, erythema multiforme, urticaria, folliculitis, and angioedema. This is a rare disorder with only a handful of documented cases. Read More

    Spectrum of orocutaneous disease associations: Genodermatoses and inflammatory conditions.
    J Am Acad Dermatol 2017 Nov;77(5):809-830
    Division of Dermatology, Baylor University Medical Center, Dallas, Texas. Electronic address:
    The oral cavity and cutaneous organ systems share a close embryologic origin. Therefore, there are numerous dermatologic conditions presenting with concomitant oral findings of which the dermatologist must be aware. The second article in this continuing medical education series reviews inflammatory orocutaneous conditions and a number of genodermatoses. Read More

    New Evidence Supporting Cyclosporine Efficacy in Epidermal Necrolysis.
    J Invest Dermatol 2017 Oct;137(10):2047-2049
    Paris, France (retired).
    Sixty years after its original description by Sir Alan Lyell, epidermal necrolysis (from Stevens-Johnson syndrome to toxic epidermal necrolysis) seems finally amenable to a specific treatment in addition to essential symptomatic measures in specialized settings. A recently published systematic review and an article by Gonzales-Herrada et al. strongly suggest that cyclosporine is effective in reducing the risk of death. Read More

    Serum IL-17 in patients with erythema multiforme or Stevens-Johnson syndrome/toxic epidermal necrolysis drug reaction, and correlation with disease severity.
    Clin Exp Dermatol 2017 Dec 20;42(8):868-873. Epub 2017 Sep 20.
    Department of Dermatology, Venereology and Andrology , Assiut University, Egypt.
    Background: There is strong evidence that drug-induced cutaneous eruptions have an immunological component. Interleukin (IL)-17, a proinflammatory cytokine that is predominantly produced by T helper 17 cells, has been linked to various autoimmune and inflammatory diseases.

    Aim: To measure serum IL-17 levels in patients with cutaneous drug reactions [erythema multiforme (EM) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)] in order to study the associations between IL-17 and disease severity. Read More

    [Targeting the skin - erythema multiforme in dogs and cats].
    Tierarztl Prax Ausg K Kleintiere Heimtiere 2017 Oct 20;45(5):352-356. Epub 2017 Sep 20.
    Teresa Böhm, Medizinische Kleintierklinik, Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München, E-Mail:
    This review article will describe the complex nature of erythema multiforme in dogs and cats. The disease pattern will be illustrated in terms of etiology, pathogenesis, clinical signs, diagnostics and therapy. Erythema multiforme is a rare, immune-mediated skin disorder with an acute specific reaction pattern of skin and mucous membranes against different underlying causes. Read More

    Autoimmune Progesterone Dermatitis Presenting as Stevens-Johnson Syndrome.
    Obstet Gynecol 2017 Oct;130(4):881-884
    Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Naval Medical Center San Diego, San Diego, California.
    Background: Autoimmune progesterone dermatitis is an uncommon disease presenting with cyclical skin eruptions corresponding with the menstrual cycle luteal phase. Because symptoms are precipitated by rising progesterone levels, treatment relies on hormone suppression.

    Case: A 22-year-old nulligravid woman presented with symptoms mistaken for Stevens-Johnson syndrome. Read More

    Rowell syndrome: targeting a true definition.
    Cutis 2017 Jul;100(1):E8-E11
    Pine Belt Dermatology and Skin Cancer Center, Petal, Mississippi, USA.
    Ever since a rare syndrome of lupus erythematosus (LE) presenting with erythema multiforme (EM)-like lesions was described in 1963, clinicians have questioned the defining characteristics of the so-called Rowell syndrome (RS) in addition to its very existence as a unique pathological entity. In this article, we present a new case of RS and investigate the various components and criteria that have been outlined in the years since this syndrome's original account. Read More

    Erythema multiforme induced by alendronate sodium in a geriatric patient: A case report and review of the literature.
    J Clin Exp Dent 2017 Jul 1;9(7):e929-e933. Epub 2017 Jul 1.
    Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
    Erythema multiforme is an uncommon acute inflammatory disorder caused by exposure to microbes or drugs. Erythema multiforme minor typically affects only one mucosa and can be associated with symmetrical target skin lesions on the extremities. The disease usually occurs in patients in their 3rd and 4th decade of life, but can also affect children and adolescents. Read More

    Erythema multiforme triggered by Treponema pallidum infection in an HIV-infected patient.
    Int J STD AIDS 2017 Jan 1:956462417726203. Epub 2017 Jan 1.
    1 37868 Emilio Ribas Infectious Diseases Institute (IIER) , São Paulo, Brazil.
    We are currently facing a worldwide epidemic of syphilis. Clinical manifestations that are rarely seen have been encountered, leading the dermatologist to confront unusual clinical conditions in daily practice. Erythema multiforme triggered by syphilis is very rare and is also seldom reported in the literature. Read More

    Paraneoplastic Pemphigus. A Life-Threatening Autoimmune Blistering Disease.
    Actas Dermosifiliogr 2017 Aug 8. Epub 2017 Aug 8.
    Servicio de Dermatología, Hospital General de México, Mexico.
    Paraneoplastic pemphigus (PNP), a subset of pemphigus, is a unique autoimmune blistering condition that can affect multiple organs other than the skin. It is a life-threatening disease associated with an underlying malignancy, most commonly of lymphoproliferative origin. The clinical picture may resemble pemphigus, pemphigoid, erythema multiforme, graft-versus-host disease, or lichen planus. Read More

    Severely Crusted Cheilitis as an Initial Presentation of Systemic Lupus Erythematosus.
    Indian J Dermatol 2017 Jul-Aug;62(4):440
    National Skin Centre, Department of Dermatology, Singapore.
    Lupus erythematosus (LE) is an autoimmune disease which may initially present solely with lip lesions. Due to a wide spectrum of presentation, these features may initially be misdiagnosed as other oral diseases such as lichen planus, erythema multiforme (EM), and actinic cheilitis, leading to a delay in diagnosis and treatment. We discuss a case of severely crusted cheilitis which was initially diagnosed as EM, with subsequent development of subacute cutaneous LE, and progression to systemic LE. Read More

    Urticaria vasculitis in a child: a case report and literature review.
    Clin Case Rep 2017 Aug 21;5(8):1255-1257. Epub 2017 Jun 21.
    Department of DermatologyHospital Universitario Severo OchoaAvenida de Orellana28911LeganésMadridSpain.
    Annular urticarial lesions in a child must establish a main differential diagnosis with urticaria multiforme, common urticaria, acute hemorrhagic edema of infancy, erythema marginatum, erythema annulare centrifugum, annular erythema in childhood, erythema multiforme, Sweet's syndrome, Schönlein-Henoch purpura, erythematosus lupus, several systemic vasculitis, and serum sickness. Read More

    Drug-Induced Oral Complications.
    Atlas Oral Maxillofac Surg Clin North Am 2017 Sep;25(2):127-132
    Department of Diagnostics and Biological Sciences, University of Colorado School of Dental Medicine, 13065 East 17th Avenue, Mail Stop F844, Aurora, CO 80045, USA; Department of Family Medicine, University of Colorado School of Medicine, 12631 East 17th Avenue, Aurora, CO 80045, USA. Electronic address:

    Three Cases of Autoimmune Progesterone Dermatitis.
    Ann Dermatol 2017 Aug 21;29(4):479-482. Epub 2017 Jun 21.
    Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
    Autoimmune progesterone dermatitis is a rare cyclic premenstrual reaction to progesterone produced during the luteal phase of the menstrual cycle. The clinical symptoms of autoimmune progesterone dermatitis overlap with other forms of dermatosis such as erythema multiforme, eczema, fixed drug eruption, urticaria, and angioedema. We experienced 3 cases of autoimmune progesterone dermatitis. Read More

    Delivering resveratrol on the buccal mucosa using mucoadhesive tablets: a potential treatment strategy for inflammatory oral lesions.
    Curr Drug Deliv 2017 Jul 26. Epub 2017 Jul 26.
    Faculty of Dentistry, Federal University of Juiz de Fora, 36036-900, Juiz de Fora, MG. Brazil.
    Resveratrol is a polyphenol which has been gaining momentum in therapeutics in the last years. In this work, we hypothesized that it could act in the prophylaxis and/or treatment of inflammatory lesions of the oral cavity through its delivery from two different formulations of buccal mucoadhesive tablets. This was assessed through permeation studies, in order to verify the drug diffusivity through the buccal mucosa, using a porcine model to predict the human in vivo behavior. Read More

    Erythema Multiforme Following lines of Blaschko.
    Am J Dermatopathol 2017 Aug;39(8):633-635
    *Department of Dermatology, Complejo Hospitalario Universitario, Santiago de Compostela, Spain †Department of Pathology, Clinical Hospital, Santiago de Compostela, Spain ‡Department of Pathology and Forensic Sciences, University of Santiago de Compostela, Santiago de Compostela, Spain.

    A Review of the Active Treatments for Toxic Epidermal Necrolysis.
    J Nippon Med Sch 2017 ;84(3):110-117
    Department of Dermatology, Nippon Medical School.
    Toxic epidermal necrolysis (TEN) is a severe adverse drug reaction associated with the separation of skin and mucous membranes at the dermal-epidermal junction. Although it is rare, many treatments have been trialed because of its high mortality rate. Active interventions performed to date include the use of systemic corticosteroids, intravenous immunoglobulins (IVIg), cyclosporine, plasmapheresis, anti-tumor necrosis factor drugs and N-acetylcysteine, but none has been established as the most effective therapy. Read More

    The thymus and activation-regulated chemokine (TARC) level in serum at an early stage of a drug eruption is a prognostic biomarker of severity of systemic inflammation.
    Allergol Int 2017 Jun 22. Epub 2017 Jun 22.
    Department of Dermatology, Shimane University Faculty of Medicine, Izumo, Japan. Electronic address:
    Background: In severe drug eruptions, precise evaluation of disease severity at an early stage is needed to start appropriate treatment. It is not always easy to diagnose these conditions at their early stage. In addition, there are no reported prognostic biomarkers of disease severity in drug eruptions. Read More

    Erythema multiforme-like lesions in primary cutaneous aggressive cytotoxic epidermotropic CD8+ T-cell lymphoma: A diagnostic and therapeutic challenge.
    J Cutan Pathol 2017 Oct 19;44(10):867-873. Epub 2017 Jul 19.
    Dermatologic Clinic, University of Milan, Milan, Italy.
    Primary cutaneous aggressive cytotoxic epidermotropic CD8+ T-cell lymphoma is an extremely rare, rapidly progressing, cutaneous lymphoma, with frequent systemic involvement and poor prognosis, that still represents a diagnostic and therapeutic challenge, especially in the early stage. Herein, we report a case of an elderly woman with a fulminant course, who at onset presented with clinical and pathological features mimicking erythema multiforme (EM) and treated with cyclosporine that led to rapid deterioration with fatal outcome 6 months after disease onset. Histopathology showed a lichenoid, epidermotropic and nodular, angiocentric, dermal and subcutaneous infiltrate of sF1, CD8+, CD45RA+ small to medium-sized atypical lymphoid cells, which strongly expressed cytotoxic markers. Read More

    Cyclosporine Use in Epidermal Necrolysis Is Associated with an Important Mortality Reduction: Evidence from Three Different Approaches.
    J Invest Dermatol 2017 Oct 17;137(10):2092-2100. Epub 2017 Jun 17.
    Clinical Pharmacology Unit, Príncipe de Asturias University Hospital, Department of Biomedical Sciences, University of Alcalá, Institute for Health Research IRYCIS, Alcalá de Henares, Madrid, Spain. Electronic address:
    Several immunomodulatory agents are used in the treatment of epidermal necrolysis, but evidence of their efficacy is limited. The Autonomous Community of Madrid has two reference burn units to which all patients with epidermal necrolysis are referred. One burn unit has mostly used cyclosporine (CsA), and the other has used non-CsA therapies (mainly high-dose intravenous immunoglobulin). Read More

    Autoimmune progesterone dermatitis presenting as fixed drug eruption: a case report.
    Dermatol Online J 2017 Jun 15;23(6). Epub 2017 Jun 15.
    Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
    Autoimmune progesterone dermatitis (APD) is a rare disorder characterized by periodic skin lesions that erupt during the luteal phase of the menstrual cycle. Clinical manifestations of APD is caused by an unusual allergy to progesterone and has a wide range of clinical manifestations from eczema and urticaria to angioedema and erythema multiforme. A 46-year-old woman described recurrent, round erythematous plaques on the lower lip, both forearms and buttocks. Read More

    Effectiveness of a fixed combination formula of ombitasvir/paritaprevir/ritonavir for hepatitis C virus infection in patients on maintenance haemodialysis.
    Nephrology (Carlton) 2017 Jul;22(7):562-565
    Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan.
    A fixed-dose formula that combines Ombitasvir (OBV), Paritaprevir (PTV) and Ritonavir (RTV) has been launched into the field of anti-HCV therapy in Japan for patients infected with HCV genotypes 1 and 2 in 2015. However, little is yet known as to the efficacy and safety of this novel therapy in patients on maintenance haemodialysis (HD). The present report describes a preliminary experience in 10 patients (five males and five females) who underwent maintenance HD. Read More

    Mucositis Secondary to Chlamydia pneumoniae Infection: Expanding the Mycoplasma pneumoniae-Induced Rash and Mucositis Concept.
    Pediatr Dermatol 2017 Jul 1;34(4):465-472. Epub 2017 Jun 1.
    Department of Dermatology, La Paz Hospital, Madrid, Spain.
    The term Mycoplasma pneumoniae-induced rash and mucositis (MIRM) was recently proposed to identify the mucocutaneous condition secondary to M. pneumoniae infection that had historically been regarded among the more confusing pathologies of erythema multiforme and Stevens-Johnson syndrome. Based on a number of previous reports, these syndromes require differentiation since they have different prognoses and specific treatment requirements. Read More

    Fuchs Syndrome: Medical Treatment of 1 Case and Literature Review.
    Case Rep Dermatol 2017 Jan-Apr;9(1):114-120. Epub 2017 Apr 18.
    Department of Odontology, University Hospital of Montpellier, Montpellier, France.
    Fuchs syndrome is a particular type of erythema multiforme major; the lesions are only found on the mucosae and specifically affect oral, ocular, and genital mucosae. The cause is not always immediately apparent, which is why this pathology requires a rigorous, detailed clinical examination to eliminate a differential diagnosis. The severity of the symptoms, particularly of oral and ocular symptoms, requires immediate treatment. Read More

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