8,051 results match your criteria Erythema Multiforme


Erythema multiforme-like rash upon anti-melanoma therapy with BRAF and MEK inhibitors.

Eur J Dermatol 2019 Feb;29(1):107-108

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1684/ejd.2019.3511DOI Listing
February 2019

[Lamotrigine induced hypersensitivity syndrome in children: a case report].

Authors:
N X Cui X P Zhu

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Apr;51(2):356-358

Department of Neonatology, Children's Hospital of Soochow University, Suzhou 215025, Jiangsu, China.

Drug induced hypersensitivity syndrome (DIHS) is often manifested as severe systemic drug trans-reactions characterized by acute and extensive skin lesions (mostly measles-like rash), fever, enlargement of lymph nodes, multiple organ involvement (hepatitis, nephritis, and pneumonia), eosinophilia and mononucleosis,within 2-6 weeks of the application of sensitizing drugs. In the early stage of the lesion, macular papules or erythema multiforme were common, and in severe cases, exfoliative dermatitis, Stevens-Johnson syndrome and toxic epidermal necrolysis were also common. Most of them developed after taking allergic drugs for 2-6 weeks (average: 3 weeks). Read More

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April 2019
2 Reads

Common Annular Lesions in the Pediatric Population: Part 2.

Pediatr Ann 2019 Mar;48(3):e135-e138

Rash is a common chief complaint for patients presenting to their physician, especially within the pediatric field. The ability to distinguish characteristics of a rash, including morphology, distribution, and configuration, is critical to forming the differential diagnosis. This is the second article of a 2-part review that discusses the common rashes that present in an annular configuration. Read More

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http://dx.doi.org/10.3928/19382359-20190222-01DOI Listing
March 2019
3 Reads

A retrospective study of the severe and uncommon variants of erythema nodosum leprosum at a tertiary health center in central India.

Int J Mycobacteriol 2019 Jan-Mar;8(1):29-34

Department of Pathology, Government Medical College, Nagpur, Maharashtra, India.

Background: Erythema nodosum leprosum (ENL) classically presents with tender, coppery, evanescent nodules along with constitutional features and visceral involvement. However, uncommon morphological variants of ENL-like erythema nodosum necroticans, erythema multiforme (EM)-like ENL, Sweet's syndrome (SS)-like ENL, Lucio phenomenon, and reactive perforating type of ENL have also been described in the literature. The primary objective of this study was to describe the clinical features of the severe and uncommon morphological variants of ENL. Read More

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http://dx.doi.org/10.4103/ijmy.ijmy_174_18DOI Listing
March 2019
1 Read

A case of febrile ulceronecrotic Mucha-Habermann disease with comorbidities.

Indian J Dermatol Venereol Leprol 2019 Mar 8. Epub 2019 Mar 8.

Department of Dermatology, K. E. M. Hospital, Pune, Maharashtra, India.

Febrile ulceronecrotic Mucha-Habermann disease is a very rare and severe variant of pityriasis lichenoides et varioliformis acuta. Adult cases are difficult to diagnose as in the early course they can mimic erythema multiforme or lymphomatoid papulosis. We report a case of a 38-year-old woman who presented with 90% body surface area involvement, fever, diarrhea, malaise and associated comorbidities. Read More

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http://dx.doi.org/10.4103/ijdvl.IJDVL_552_17DOI Listing
March 2019
7 Reads

Bullous Pemphigoid with Atypical Skin Lesions and Acute Interstitial Nephritis: A Case Report and Focused Literature Review.

Am J Case Rep 2019 Feb 18;20:212-218. Epub 2019 Feb 18.

Department of Internal Medicine, Mount Sinai Hospital, Chicago, IL, USA.

BACKGROUND The hallmark of bullous pemphigoid (BP) is widespread tense blisters arising on normal or erythematous skin, often with marked pruritus, the diagnosis of which is confirmed by direct immunofluorescence (DIF). BP is an autoimmune process that can be induced, though rarely, by medications. Drug-induced BP often has atypical clinical presentation, which requires a good understanding of other dermatological conditions with similar presentations, in particular, bullous subtype of erythema multiforme. Read More

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http://dx.doi.org/10.12659/AJCR.911422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6388647PMC
February 2019

Bronchiolitis Obliterans After Cefuroxime-Induced Stevens-Johnson Syndrome.

Am J Case Rep 2019 Feb 9;20:171-174. Epub 2019 Feb 9.

Department of Inernal Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Jeddah, Saudi Arabia.

BACKGROUND Bronchiolitis obliterans is the term used to describe a clinical syndrome of irreversible airflow obstruction. Among the etiologies linked to this entity is the rarely reported association with Stevens-Johnson syndrome, which has had a poor outcome in most of the previously published cases. The optimum management of bronchiolitis obliterans as a complication of Stevens-Johnson syndrome is not well defined. Read More

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http://dx.doi.org/10.12659/AJCR.913723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380208PMC
February 2019
1 Read

Pemphigoid Gestationis Mimicking Erythema Multiforme With Mucosal Involvement.

Actas Dermosifiliogr 2019 Feb 4. Epub 2019 Feb 4.

Departamento de Dermatología, Hospital del Mar-Parc Salut Mar, Barcelona, España.

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http://dx.doi.org/10.1016/j.ad.2018.02.038DOI Listing
February 2019
1 Read

Epidermal necrolysis: SCORTEN performance in AIDS and non-AIDS patients.

An Bras Dermatol 2019 Jan-Feb;94(1):17-23

Division of Dermatology, Department of Internal Medicine, Universidade Estadual de Ponta Grossa, Ponta Grossa (PR), Brazil.

Background: Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening blistering drug reactions with high incidence of ocular sequela. The term 'Epidermal Necrolysis' has been recently used to better describe the full spectrum of the disease that includes Stevens-Johnson syndrome and toxic epidermal necrolysis at opposite ends, which differ by the extent of body surface area with epidermal detachment. SCORTEN is a mortality prognosis score for 'Epidermal Necrolysis' cases that still needed validation in acquired immunodeficiency syndrome. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20196864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360969PMC
February 2019
2 Reads

Ulcerated Lesions of the Oral Mucosa: Clinical and Histologic Review.

Head Neck Pathol 2019 Mar 7;13(1):91-102. Epub 2019 Mar 7.

Department of Diagnostic and Biomedical Sciences, University of Texas at Houston Health Science Center School of Dentistry, Houston, TX, USA.

Ulcerated lesions of the oral cavity have many underlying etiologic factors, most commonly infection, immune related, traumatic, or neoplastic. A detailed patient history is critical in assessing ulcerative oral lesions and should include a complete medical and medication history; whether an inciting or triggering trauma, condition, or medication can be identified; the length of time the lesion has been present; the frequency of episodes in recurrent cases; the presence or absence of pain; and the growth of the lesion over time. For multiple or recurrent lesions the presence or history of ulcers on the skin, genital areas, or eyes should be evaluated along with any accompanying systemic symptoms such as fever, arthritis, or other signs of underlying systemic disease. Read More

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http://dx.doi.org/10.1007/s12105-018-0981-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405793PMC
March 2019
2 Reads

Erythema multiforme: Differences between HSV-1 and HSV-2 and management of the disease-A case report and mini review.

Dermatol Ther 2019 Jan 28:e12847. Epub 2019 Jan 28.

Department of Dermatology, Sapienza University of Rome, Sant'Andrea General Hospital, Rome, Italy.

Erythema multiforme (EM) is an immune-mediated reaction characterized by target lesions and with possible mucosal involvement. Its most frequent cause is HSV, with HSV-1 more common than -2. It is usually self-limited but it can show recurrences. Read More

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http://dx.doi.org/10.1111/dth.12847DOI Listing
January 2019
1 Read

Interventions for erythema multiforme: a systematic review.

J Eur Acad Dermatol Venereol 2019 Jan 25. Epub 2019 Jan 25.

Service de Dermatologie, AP-HP, Hôpital Henri Mondor, Créteil, France.

Treatment of erythema multiforme (EM) is not codified. We performed a systematic review of the effect of any topical or systemic treatment on time to healing and frequency of episodes with acute and chronic forms of EM in adults. Four databases (MEDLINE, CENTRAL, EMBASE and LILACS) and other sources were searched for articles published up to 20 March 2018. Read More

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http://dx.doi.org/10.1111/jdv.15447DOI Listing
January 2019
1 Read

Analysis of Individual Case Safety Reports of Severe Cutaneous Adverse Reactions in Korea.

Yonsei Med J 2019 Feb;60(2):208-215

Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, Korea.

Purpose: Despite morbidities and fatalities, nationwide epidemiologic data for severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS), are not widely available. We aimed to investigate SCAR epidemiology over the last two decades in Korea.

Materials And Methods: We analyzed individual case safety reports (ICSRs) of SCARs in the Korea Adverse Event Reporting System from 1988 to 2013. Read More

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http://dx.doi.org/10.3349/ymj.2019.60.2.208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342723PMC
February 2019
4 Reads

Lacrimal passage irrigation in children with Stevens-Johnson syndrome or toxic epidermal necrolysis: a five-year retrospective study.

BMC Ophthalmol 2019 Jan 18;19(1):22. Epub 2019 Jan 18.

Department of Ophthalmology, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.

Background: To identity the effect of lacrimal system irrigation in the acute stage in children with Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN).

Methods: A retrospective review of 39 patients with SJS or TEN from 2012 to 2017 was analyzed. Patients were divided into two subgroups according to whether they received irrigation in the acute stage. Read More

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http://dx.doi.org/10.1186/s12886-018-1014-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339389PMC
January 2019
6 Reads

Oral findings in Rett syndrome: An update and review of the literature.

Dent Med Probl 2018 Oct-Dec;55(4):441-445

Department of Surgery and Translational Medicine, University of Milano-Bicocca, Milan, Italy.

Rett syndrome is a progressive pediatric neurodevelopmental disorder, predominantly affecting females, characterized by a seemingly normal prenatal and perinatal period, followed by neurodevelopmental stagnation, and then rapid regression.The purpose of this study was to provide an update of the literature on the oral aspects of Rett syndrome and their possible treatment in patients suffering from this pathology. After an electronic and manual search in MEDLINE (PubMed) and the Cochrane Library, 12 articles were found, for a total of 142 patients affected by Rett syndrome. Read More

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http://dx.doi.org/10.17219/dmp/99203DOI Listing
January 2019
3 Reads

Allopurinol-Induced Stevens-Johnson Syndrome.

Am J Med Sci 2019 Apr 4;357(4):348-351. Epub 2018 Dec 4.

Department of Critical Care Medicine, Maimonides Medical Center, Brooklyn, New York.

Allopurinol is a first line agent in treating gout, but it also carries the risk of severe side effects. Stevens-Johnson syndrome (SJS) is one of the life threatening severe cutaneous adverse reactions caused by allopurinol. The severity of the severe cutaneous adverse reactions can be categorized based upon the area of skin involvement: (1) erythema multiforme major limited to 1-2 % of the body surface area (BSA); (2) SJS involving <10% of the BSA, (3) SJS and toxic epidermal necrolysis overlap involving 10-30% of the BSA and (4) toxic epidermal necrolysis syndrome involving >30% of the BSA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029629183044
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http://dx.doi.org/10.1016/j.amjms.2018.11.018DOI Listing
April 2019
11 Reads

Spontaneous Resolution of Cholesteatoma in a Patient on Long-Term Infliximab.

Ann Otol Rhinol Laryngol 2019 Apr 11;128(4):365-368. Epub 2019 Jan 11.

2 MEEI, Boston, MA, USA.

Objective:: To describe an observed case of spontaneous regression of cholesteatoma in a patient on chronic anti-tumor necrosis factor-alpha (TNF-a) therapy and inspire further research into the role of TNF-a in cholesteatoma.

Methods:: Clinical assessment of disease in a single-patient case report.

Results:: A 49-year-old woman suffered a severe case of Stevens-Johnson syndrome when she was 12 years old, leaving her with bilateral corneal opacification and tympanic membrane perforations with extensive cholesteatoma. Read More

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http://dx.doi.org/10.1177/0003489418823790DOI Listing
April 2019
9 Reads

Dietary supplement product composed of natural ingredients as a suspected cause of erythema multiforme: A case report and identification for the confident false positivity of lymphocyte transformation test.

J Dermatol 2019 Mar 9;46(3):234-239. Epub 2019 Jan 9.

Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.

Growing and sustainable consumption of health-care products raises a controversial issue underlying the reliability of an in vitro diagnostic approach for adverse skin reaction. This report aimed to: (i) discuss the causative nature of a commercial dietary supplement composed of natural ingredients, particularly an Euglena-containing product, suspicious for erythema multiforme in our exemplified case; and (ii) to address the assay suitability of the lymphocyte transformation test (LTT) for identifying allergic reaction to any ingredient(s) of the product. A Japanese elderly man developed erythema multiforme after intake of a commercially available natural dietary product, whose LTT was positive. Read More

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http://doi.wiley.com/10.1111/1346-8138.14739
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http://dx.doi.org/10.1111/1346-8138.14739DOI Listing
March 2019
20 Reads

Markers of systemic involvement and death in hospitalized cancer patients with severe cutaneous adverse reactions.

J Am Acad Dermatol 2019 Mar 26;80(3):608-616. Epub 2018 Oct 26.

Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, New York; Department of Dermatology, Weill Cornell Medical College, New York, New York. Electronic address:

Background: Severe cutaneous adverse reactions (SCARs) are frequent in inpatient oncology. Early intervention might reduce morbidity, mortality, and hospitalization costs; however, current clinical and histologic features are unreliable SCAR predictors. There is a need to identify rational markers of SCARs that could lead to effective therapeutic interventions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183280
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http://dx.doi.org/10.1016/j.jaad.2018.10.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372330PMC
March 2019
15 Reads

Oxcarbazepine-Induced Stevens-Johnson Syndrome.

Prim Care Companion CNS Disord 2018 Dec 20;20(6). Epub 2018 Dec 20.

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http://dx.doi.org/10.4088/PCC.18l02304DOI Listing
December 2018
4 Reads

Basiliximab treatment of severe GVHD induced by donor lymphocyte infusion with interferon-a.

Dermatol Ther 2018 Dec 27:e12808. Epub 2018 Dec 27.

Peking University People's Hospital, Department of Dermatology, Beijing, China.

The development of acute graft-versus-host-disease (GVHD) in recipients of donor lymphocyte infusion (DLI) is not rare and the complication is quite often fatal. We describe a severe skin GVHD patient who responded well to basiliximab. A 20-year-old male who received a hematopoietic stem cell transplantation at his age of 18. Read More

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http://doi.wiley.com/10.1111/dth.12808
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http://dx.doi.org/10.1111/dth.12808DOI Listing
December 2018
11 Reads

Stevens Johnson Syndrome with Vaginal Pain and Lesions as Initial Presentation.

Am J Case Rep 2018 Dec 21;19:1519-1521. Epub 2018 Dec 21.

Department of Obstetrics Gynecology and Women's Health, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, USA.

BACKGROUND Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are causes of rare but life-threatening emergencies characterized by desquamation of the skin and mucosa. As SJS most commonly presents with skin rash followed by mucosal involvement, we present a case of vulvovaginal lesions as the initial presentation with progression to SJS after re-exposure to the culprit drug. CASE REPORT A 27-year-old female with acute cystitis was given trimethoprim-sulfamethoxazole. Read More

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http://dx.doi.org/10.12659/AJCR.912123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322057PMC
December 2018
3 Reads

Variants of Erythema Multiforme: A Case Report and Literature Review.

Cureus 2018 Oct 16;10(10):e3459. Epub 2018 Oct 16.

Emergency Medicine, University of Arizona College of Medicine, Tucson, USA.

Erythema multiforme is an acute skin condition characterized by targetoid lesions and occurs most frequently in young adults, particularly males. There are two variants of this condition, one with mucosal involvement, termed erythema multiforme major, and one without mucosal involvement, known as erythema multiforme minor. Due to the similarities in clinical and histological findings, it was previously believed that erythema multiforme major was indistinguishable from Steven-Johnson syndrome (SJS). Read More

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http://dx.doi.org/10.7759/cureus.3459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298627PMC
October 2018

Pityriasis Rosea: Clinical Profile from Central India.

Indian Dermatol Online J 2018 Nov-Dec;9(6):414-417

Department of Dermatology, AIIMS, Raipur, India.

Background: Pityriasis rosea (PR) is a common, self-limiting dermatologic disorder. The information regarding the clinical profile of the disease in India is limited because of inadequate studies.

Materials And Methods: A retrospective, record-based study on the clinical presentation of PR was conducted in a tertiary care center based in Central India. Read More

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http://dx.doi.org/10.4103/idoj.IDOJ_12_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232983PMC
December 2018
2 Reads

Stevens-Johnson syndrome-like reaction without mucosal lesions associated with cyclophosphamide.

Authors:
Yang Lo Chun-An Yao

Indian J Dermatol Venereol Leprol 2019 Jan-Feb;85(1):101-103

Department of Dermatology, Cathay General Hospital, Taipei, Taiwan.

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http://dx.doi.org/10.4103/ijdvl.IJDVL_903_17DOI Listing
April 2019
3 Reads

Discontinuation of sorafenib can lead to the emergence of FLT3-ITD-positive acute myeloid leukemia.

J Oncol Pharm Pract 2018 Dec 4:1078155218816768. Epub 2018 Dec 4.

1 Division of Medical Oncology and Hematology, Kobe University Hospital, Kobe, Hyogo, Japan.

A 69-year-old woman who had been diagnosed with unresectable papillary thyroid cancer was referred to our hospital. We initially treated her with sorafenib, but she subsequently developed erythema multiforme, which was suspected to be a drug rush due to sorafenib; therefore, sorafenib was discontinued. At the time of discontinuation, immature blast cells were detected in her peripheral blood. Read More

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http://dx.doi.org/10.1177/1078155218816768DOI Listing
December 2018
3 Reads

Toxic epidermal necrolysis after yellow fever vaccination.

An Bras Dermatol 2018 Nov/Dec;93(6):942-943

Medical Residency Program in Dermatology, Faculdade de Medicina de Jundiaí, Jundiaí (SP), Brazil.

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http://dx.doi.org/10.1590/abd1806-4841.20188237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256206PMC
February 2019
3 Reads

Autoimmune progesterone dermatitis manifesting as generalized fixed drug eruption.

An Bras Dermatol 2018 Nov/Dec;93(6):874-877

Department of Pathology, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Autoimmune progesterone dermatitis is an uncommon, poorly recognized and under-diagnosed catamenial dermatosis associated with hypersensitivity reactions to progestagens. Most cases manifest as urticaria, eczema or erythema multiforme-like. A 26-year-old woman developed violaceous plaques on the groin and abdomen, 4 days after a spontaneous abortion resolved with uterine curettage. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20187290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256208PMC
February 2019
9 Reads

Secondary syphilis presenting as erythema multiforme in a HIV-positive homosexual man: a case report and literature review.

Int J STD AIDS 2019 Mar 27;30(3):304-309. Epub 2018 Nov 27.

1 Dermatology Hospital of Southern Medical University (Guangdong Provincial Dermatology Hospital), Guangzhou, China.

Early syphilis can rarely cause erythema multiforme-type eruptions as well as triggering erythema multiforme (EM). EM-like lesions in secondary syphilis are characterized by clinical features of EM and laboratory tests consistent with secondary syphilis and the skin histology shows predominantly a plasma cell infiltrate with the presence of treponemes. When EM is triggered by early syphilis, the skin histology shows mixed inflammatory cells usually in the absence of treponemes in the skin lesion. Read More

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http://dx.doi.org/10.1177/0956462418805197DOI Listing
March 2019
10 Reads

Herpes-Associated Erythema Multiforme.

JAMA Dermatol 2019 Jan;155(1):108

Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1001/jamadermatol.2018.3973DOI Listing
January 2019
1 Read

Treatment of oral manifestations of toxic epidermal necrolysis with low-level laser therapy in a pediatric patient.

Pediatr Dermatol 2019 Jan 26;36(1):e27-e30. Epub 2018 Nov 26.

Department of Oral Surgery and Pathology, Faculty of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Drug-induced reactions are complications associated with high mortality and significant morbidity. Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of these conditions, which are characterized by skin and mucous lesions. Here, we report a case of a 9-year-old girl who presented with blisters associated with an extensive vesicular rash and multiple ulcerations on the lips and oral cavity. Read More

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http://doi.wiley.com/10.1111/pde.13719
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http://dx.doi.org/10.1111/pde.13719DOI Listing
January 2019
19 Reads

Erythema multiforme-like contact dermatitis caused by herbal medicine.

Contact Dermatitis 2019 Mar 9;80(3):189-190. Epub 2019 Jan 9.

Department of Dermatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

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http://dx.doi.org/10.1111/cod.13172DOI Listing
March 2019
4 Reads

Propranolol eye drops in patients with corneal neovascularization.

Medicine (Baltimore) 2018 Nov;97(45):e13002

Pediatric Ophthalmology Unit, Niguarda Ca' Granda Metropolitan Hospital, Milan, Italy.

Rationale: Studies performed in animal models of corneal neovascularization suggested the possible efficacy of a treatment with propranolol. Corneal neovascularization is one of the most feared complications of Stevens-Johnson syndrome that frequently involves ocular surface. We report the first 2 patients with severe ocular neo-vascularization treated with different degrees of success, with propranolol eye drops. Read More

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http://Insights.ovid.com/crossref?an=00005792-201811090-0001
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http://dx.doi.org/10.1097/MD.0000000000013002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250516PMC
November 2018
26 Reads

Inflammatory eruptions associated with immune checkpoint inhibitor therapy: A single-institution retrospective analysis with stratification of reactions by toxicity and implications for management.

J Am Acad Dermatol 2019 Apr 3;80(4):990-997. Epub 2018 Nov 3.

Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut. Electronic address:

Background: There is increasing recognition of distinct inflammatory eruptions associated with checkpoint inhibitors. A better understanding of their severity, therapeutic response, and impact on cancer treatment is needed.

Objective: To analyze the different rashes associated with immunotherapy referred to our institution's oncodermatology clinic and inpatient consultative service and to evaluate their therapeutic response and impact on immunotherapy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183283
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http://dx.doi.org/10.1016/j.jaad.2018.10.062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420863PMC
April 2019
9 Reads

Autoimmune Progesterone Dermatitis Diagnosed by Lymphocyte Transformation Test and Progesterone Provocation Test.

Acta Dermatovenerol Croat 2018 Oct;26(3):276-277

Assoc. Prof. Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology University Hospital Center Zagreb School of Medicine University of Zagreb, Šalata 4, 10000 Zagreb, Croatia;

Autoimmune progesterone dermatitis (APD) is rare autoimmune response to endogenous progesterone or to earlier exposure to exogenous progesterone (1). Skin lesions typically occur due to increases in progesterone during the luteal phase of the menstrual cycle (2). A-31-year-old mother of two children presented to our Department with a 5-year history of pruritic and painful erythematosus macules, papules, and patches on her neck, pectoral region, and face, which appeared 2-3 days before the onset of menses and gradually resolved 7-10 days later (Figure 1). Read More

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October 2018
15 Reads

Generalized bullous fixed-drug eruption secondary to the influenza vaccine.

JAAD Case Rep 2018 Oct 12;4(9):953-955. Epub 2018 Oct 12.

University of North Carolina School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1016/j.jdcr.2018.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197945PMC
October 2018
5 Reads

Deflazacort-Induced Erythema Multiforme Exudativum Successfully Treated With a Single Dose of Etanercept.

J Investig Allergol Clin Immunol 2018 Oct;28(5):338-339

Dermatology Department Hospital Universitario de Fuenlabrada, Fuenlabrada, Spain.

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http://dx.doi.org/10.18176/jiaci.0277DOI Listing
October 2018
2 Reads

Postpartum eruption of enoxaparin-induced erythema multiforme.

Clin Case Rep 2018 Oct 23;6(10):1966-1969. Epub 2018 Aug 23.

Division of Dermatology NorthShore University HealthSystem Skokie Illinois.

Enoxaparin is a commonly used hospital medication and in rare instances may result in development of erythema multiforme. Management of these patients can be challenging. Physicians must maintain a high index of suspicion and consider the indication for enoxaparin therapy prior to withdrawal of the medication. Read More

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http://dx.doi.org/10.1002/ccr3.1752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186885PMC
October 2018

Erythema Multiforme Major After Immunotherapy With Diphenylcyclopropenone for Alopecia Areata.

Dermatitis 2018 Nov/Dec;29(6):348-349

MS II, Sidney Kimmel Medical College Thomas Jefferson University Philadelphia, PA Department of Dermatology, School of Medicine University of Maryland Baltimore Department of Dermatology and Cutaneous Biology Sidney Kimmel Medical College Thomas Jefferson University Philadelphia, PA

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http://dx.doi.org/10.1097/DER.0000000000000415DOI Listing
October 2018
8 Reads

[Boston Keratoprosthesis with temporal aponeurosis graft: A solution when there seems to be no more].

J Fr Ophtalmol 2018 Nov 19;41(9):830-835. Epub 2018 Oct 19.

Service d'ophtalmologie II, centre hospitalier national des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France.

Purpose: To report cases of patients with severe bilateral corneal blindness and recurrent refractory perforation to keratoplasty and conventional treatment, for whom Boston keratoprosthesis (KP) was a satisfactory alternative when combined with a temporalis aponeurosis graft.

Description Of Cases: The first patient had progressive Lyell syndrome with spontaneous corneal perforation. The second had a severe graft vs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01815512183029
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http://dx.doi.org/10.1016/j.jfo.2018.01.010DOI Listing
November 2018
20 Reads

SLE in a Male Patient Presented Initially as Rowell's Syndrome.

J Assoc Physicians India 2018 01;66(1):98-9

Professor, Department of Tropical Medicine, School of Tropical Medicine, Kolkata, West Bengal.

A 22 year old male Indian patient presented with high grade fever, multiple joint pain, low back pain, generalized body ache since 6 months and erythematous pruritic rashes and atypical annular target like lesions over face, arm, leg and back and ulcers on hard palate and buccal mucosa for 2 months. Laboratory investigations showed a speckled pattern anti-nuclear antibody with a titer >1:160 and positive SS-A, dsDNA auto-antibodies and Rheumatoid factor. Diagnosis of Rowell's syndrome was made based on clinical and laboratory finding and the patient was treated with oral prednisolone (50 mg/day), hydroxychloroquine (200 mg q12h) and pulse cyclophosphamide (700 mg) chemotherapy. Read More

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January 2018
16 Reads

[When drugs induce cutaneous lupus erythematosus].

Ugeskr Laeger 2018 Oct;180(41)

Drug-induced subacute cutaneous lupus erythematosus (DI-SCLE) is defined as an adverse reaction to continuous use of a culprit drug. The reaction resolves upon drug withdrawal. More than 50 drugs have been linked to DI-SCLE, and it is estimated, that around 20% of the SCLE cases are drug-induced. Read More

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October 2018
5 Reads

Bartonella henselae in a dog with ear tip vasculitis.

Vet Dermatol 2018 Dec 14;29(6):537-e180. Epub 2018 Oct 14.

Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, 1050 William Moore Drive, Raleigh, NC, 27607, USA.

Background: Bartonella henselae, a Gram-negative, zoonotic, alpha-proteobacteria has been previously implicated in association with cutaneous vasoproliferative lesions (bacillary angiomatosis), nodular panniculitis and multifocal erythema (erythema multiforme) in dogs.

Objective: Describe clinical, microbiological and histological lesions in a dog with ear margin vasculitis and B. henselae infection. Read More

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http://dx.doi.org/10.1111/vde.12695DOI Listing
December 2018
3 Reads

Toxic epidermal necrolysis: the red eye and red herrings in casualty.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Department of Ophthalmology, Queen Elizabeth Hospital Birmingham, Birmingham, Birmingham, UK.

A 38-year-old woman presented to casualty with bilateral red eyes associated with a recent upper respiratory tract infection. This was initially diagnosed as conjunctivitis, however systemic review revealed an erythematous facial and skin rash, mildly swollen lips and mild swallowing difficulties. The patient was referred for an urgent medical assessment, by which time she was found to have erythema affecting 54% of her body surface area and diagnosed with suspected toxic epidermal necrolysis (TEN). Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22586
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http://dx.doi.org/10.1136/bcr-2018-225861DOI Listing
October 2018
14 Reads

Fluoxetine-induced Stevens-Johnson syndrome and liver injury.

J Clin Pharm Ther 2019 Feb 8;44(1):115-118. Epub 2018 Oct 8.

Division of Gastroenterology and Hepatology, Department of Medicine, Cook County Health and Hospital System, Chicago, Illinois.

What Is Known And Objective: Drug-induced liver injuries (DILI) are overall rare and often associated with use of medications. Medications are also the most common aetiology of Stevens-Johnson syndrome (SJS), but SJS is seldom seen concomitantly with liver injury. Many common drugs can cause either one of these conditions; however, there are no reported cases of concomitant DILI and SJS secondary to fluoxetine. Read More

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http://doi.wiley.com/10.1111/jcpt.12760
Publisher Site
http://dx.doi.org/10.1111/jcpt.12760DOI Listing
February 2019
36 Reads

A Rare Case Report of Giant Cell Tumor of the Sphenoid Bone in a Patient Who Developed "Erythema Multiforme Associated with Phenytoin and Cranial Radiation Therapy Syndrome".

Asian J Neurosurg 2018 Jul-Sep;13(3):877-880

Department of Radiotherapy, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.

Giant cell tumors (GCTs) are rare, usually affecting the epiphyses in long bones of the extremities. GCTs may be locally aggressive with a high rate of local recurrence and exhibit the potential for distant metastasis. They seldom occur in the skull, where they preferentially affect the sphenoid and temporal bones. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_352_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159083PMC
October 2018
2 Reads

Reasons for inpatient admissions to the dermatology department in Lomé, Togo : Trends between 1992 to 2005 and 2005 to 2016.

Med Sante Trop 2018 Aug;28(3):270-272

CHU Sylvanus Olympio, Lomé, Togo.

The aim of this study was to report the frequency of and reasons for dermatology admissions in Lomé (Togo) between 2005 and 2016. This retrospective study examined records from August 2005 to December 2016 from the dermatology departments of the two teaching hospitals in Lomé, Togo. During the study period, 454 (1. Read More

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http://dx.doi.org/10.1684/mst.2018.0813DOI Listing
August 2018
5 Reads

Treatment of Skin Reaction Induced by Nivolumab Combined with Radiotherapy in Non-small Cell Lung Cancer: A Case Report.

Chin Med Sci J 2018 Sep;33(3):183-187

Department of Oncology, Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, Shandong 266042, China.

Skin reaction or dermatological toxicities induced by immunotherapy is common. It usually manifests skin rash or erythema and can be cured by skin lotion or steroid. Nivolumab, a human IgG4 programmed cell death protein 1 (PD-1) inhibitor, blocks T cells activation preventing signal and allows the immune system to clear cancer cells. Read More

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http://dx.doi.org/10.24920/31805DOI Listing
September 2018
1 Read