8,007 results match your criteria Erythema Multiforme


Bullous Pemphigoid with Atypical Skin Lesions and Acute Interstitial Nephritis: A Case Report and Focused Literature Review.

Am J Case Rep 2019 Feb 18;20:212-218. Epub 2019 Feb 18.

Department of Internal Medicine, Mount Sinai Hospital, Chicago, IL, USA.

BACKGROUND The hallmark of bullous pemphigoid (BP) is widespread tense blisters arising on normal or erythematous skin, often with marked pruritus, the diagnosis of which is confirmed by direct immunofluorescence (DIF). BP is an autoimmune process that can be induced, though rarely, by medications. Drug-induced BP often has atypical clinical presentation, which requires a good understanding of other dermatological conditions with similar presentations, in particular, bullous subtype of erythema multiforme. Read More

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http://dx.doi.org/10.12659/AJCR.911422DOI Listing
February 2019

Pemphigoid Gestationis Mimicking Erythema Multiforme With Mucosal Involvement.

Actas Dermosifiliogr 2019 Feb 4. Epub 2019 Feb 4.

Departamento de Dermatología, Hospital del Mar-Parc Salut Mar, Barcelona, España.

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http://dx.doi.org/10.1016/j.ad.2018.02.038DOI Listing
February 2019

Ulcerated Lesions of the Oral Mucosa: Clinical and Histologic Review.

Head Neck Pathol 2019 Jan 31. Epub 2019 Jan 31.

Department of Diagnostic and Biomedical Sciences, University of Texas at Houston Health Science Center School of Dentistry, Houston, TX, USA.

Ulcerated lesions of the oral cavity have many underlying etiologic factors, most commonly infection, immune related, traumatic, or neoplastic. A detailed patient history is critical in assessing ulcerative oral lesions and should include a complete medical and medication history; whether an inciting or triggering trauma, condition, or medication can be identified; the length of time the lesion has been present; the frequency of episodes in recurrent cases; the presence or absence of pain; and the growth of the lesion over time. For multiple or recurrent lesions the presence or history of ulcers on the skin, genital areas, or eyes should be evaluated along with any accompanying systemic symptoms such as fever, arthritis, or other signs of underlying systemic disease. Read More

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http://dx.doi.org/10.1007/s12105-018-0981-8DOI Listing
January 2019
1 Read

Erythema multiforme: Differences between HSV-1 and HSV-2 and management of the disease-A case report and mini review.

Dermatol Ther 2019 Jan 28:e12847. Epub 2019 Jan 28.

Department of Dermatology, Sapienza University of Rome, Sant'Andrea General Hospital, Rome, Italy.

Erythema multiforme (EM) is an immune-mediated reaction characterized by target lesions and with possible mucosal involvement. Its most frequent cause is HSV, with HSV-1 more common than -2. It is usually self-limited but it can show recurrences. Read More

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http://dx.doi.org/10.1111/dth.12847DOI Listing
January 2019

Interventions for erythema multiforme: a systematic review.

J Eur Acad Dermatol Venereol 2019 Jan 25. Epub 2019 Jan 25.

Service de Dermatologie, AP-HP, Hôpital Henri Mondor, F-9400, Créteil, France.

Treatment of erythema multiforme (EM) is not codified. We performed a systematic review of the effect of any topical or systemic treatment on time to healing and frequency of episodes with acute and chronic forms of EM in adults. Four databases (MEDLINE, CENTRAL, EMBASE and LILACS) and other sources were searched for articles published up to March20, 2018. Read More

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http://dx.doi.org/10.1111/jdv.15447DOI Listing
January 2019

Lacrimal passage irrigation in children with Stevens-Johnson syndrome or toxic epidermal necrolysis: a five-year retrospective study.

BMC Ophthalmol 2019 Jan 18;19(1):22. Epub 2019 Jan 18.

Department of Ophthalmology, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China.

Background: To identity the effect of lacrimal system irrigation in the acute stage in children with Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN).

Methods: A retrospective review of 39 patients with SJS or TEN from 2012 to 2017 was analyzed. Patients were divided into two subgroups according to whether they received irrigation in the acute stage. Read More

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http://dx.doi.org/10.1186/s12886-018-1014-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339389PMC
January 2019
3 Reads

Oral findings in Rett syndrome: An update and review of the literature.

Dent Med Probl 2018 Oct-Dec;55(4):441-445

Department of Surgery and Translational Medicine, University of Milano-Bicocca, Milan, Italy.

Rett syndrome is a progressive pediatric neurodevelopmental disorder, predominantly affecting females, characterized by a seemingly normal prenatal and perinatal period, followed by neurodevelopmental stagnation, and then rapid regression.The purpose of this study was to provide an update of the literature on the oral aspects of Rett syndrome and their possible treatment in patients suffering from this pathology. After an electronic and manual search in MEDLINE (PubMed) and the Cochrane Library, 12 articles were found, for a total of 142 patients affected by Rett syndrome. Read More

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http://dx.doi.org/10.17219/dmp/99203DOI Listing
January 2019
2 Reads

Allopurinol-Induced Stevens-Johnson Syndrome.

Am J Med Sci 2018 Dec 4. Epub 2018 Dec 4.

Department of Critical Care Medicine, Maimonides Medical Center, Brooklyn, New York.

Allopurinol is a first line agent in treating gout, but it also carries the risk of severe side effects. Stevens-Johnson syndrome (SJS) is one of the life threatening severe cutaneous adverse reactions caused by allopurinol. The severity of the severe cutaneous adverse reactions can be categorized based upon the area of skin involvement: (1) erythema multiforme major limited to 1-2 % of the body surface area (BSA); (2) SJS involving <10% of the BSA, (3) SJS and toxic epidermal necrolysis overlap involving 10-30% of the BSA and (4) toxic epidermal necrolysis syndrome involving >30% of the BSA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029629183044
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http://dx.doi.org/10.1016/j.amjms.2018.11.018DOI Listing
December 2018
6 Reads

Dietary supplement product composed of natural ingredients as a suspected cause of erythema multiforme: A case report and identification for the confident false positivity of lymphocyte transformation test.

J Dermatol 2019 Jan 9. Epub 2019 Jan 9.

Department of Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan.

Growing and sustainable consumption of health-care products raises a controversial issue underlying the reliability of an in vitro diagnostic approach for adverse skin reaction. This report aimed to: (i) discuss the causative nature of a commercial dietary supplement composed of natural ingredients, particularly an Euglena-containing product, suspicious for erythema multiforme in our exemplified case; and (ii) to address the assay suitability of the lymphocyte transformation test (LTT) for identifying allergic reaction to any ingredient(s) of the product. A Japanese elderly man developed erythema multiforme after intake of a commercially available natural dietary product, whose LTT was positive. Read More

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http://doi.wiley.com/10.1111/1346-8138.14739
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http://dx.doi.org/10.1111/1346-8138.14739DOI Listing
January 2019
8 Reads

Basiliximab treatment of severe GVHD induced by donor lymphocyte infusion with interferon-a.

Dermatol Ther 2018 Dec 27:e12808. Epub 2018 Dec 27.

Peking University People's Hospital, Department of Dermatology, Beijing, China.

The development of acute graft-versus-host-disease (GVHD) in recipients of donor lymphocyte infusion (DLI) is not rare and the complication is quite often fatal. We describe a severe skin GVHD patient who responded well to basiliximab. A 20-year-old male who received a hematopoietic stem cell transplantation at his age of 18. Read More

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http://doi.wiley.com/10.1111/dth.12808
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http://dx.doi.org/10.1111/dth.12808DOI Listing
December 2018
8 Reads

Variants of Erythema Multiforme: A Case Report and Literature Review.

Cureus 2018 Oct 16;10(10):e3459. Epub 2018 Oct 16.

Emergency Medicine, University of Arizona College of Medicine, Tucson, USA.

Erythema multiforme is an acute skin condition characterized by targetoid lesions and occurs most frequently in young adults, particularly males. There are two variants of this condition, one with mucosal involvement, termed erythema multiforme major, and one without mucosal involvement, known as erythema multiforme minor. Due to the similarities in clinical and histological findings, it was previously believed that erythema multiforme major was indistinguishable from Steven-Johnson syndrome (SJS). Read More

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http://dx.doi.org/10.7759/cureus.3459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298627PMC
October 2018

Pityriasis Rosea: Clinical Profile from Central India.

Indian Dermatol Online J 2018 Nov-Dec;9(6):414-417

Department of Dermatology, AIIMS, Raipur, India.

Background: Pityriasis rosea (PR) is a common, self-limiting dermatologic disorder. The information regarding the clinical profile of the disease in India is limited because of inadequate studies.

Materials And Methods: A retrospective, record-based study on the clinical presentation of PR was conducted in a tertiary care center based in Central India. Read More

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http://dx.doi.org/10.4103/idoj.IDOJ_12_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232983PMC
December 2018
1 Read

Discontinuation of sorafenib can lead to the emergence of FLT3-ITD-positive acute myeloid leukemia.

J Oncol Pharm Pract 2018 Dec 4:1078155218816768. Epub 2018 Dec 4.

1 Division of Medical Oncology and Hematology, Kobe University Hospital, Kobe, Hyogo, Japan.

A 69-year-old woman who had been diagnosed with unresectable papillary thyroid cancer was referred to our hospital. We initially treated her with sorafenib, but she subsequently developed erythema multiforme, which was suspected to be a drug rush due to sorafenib; therefore, sorafenib was discontinued. At the time of discontinuation, immature blast cells were detected in her peripheral blood. Read More

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http://dx.doi.org/10.1177/1078155218816768DOI Listing
December 2018
1 Read

Toxic epidermal necrolysis after yellow fever vaccination.

An Bras Dermatol 2018 Nov/Dec;93(6):942-943

Medical Residency Program in Dermatology, Faculdade de Medicina de Jundiaí, Jundiaí (SP), Brazil.

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http://dx.doi.org/10.1590/abd1806-4841.20188237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256206PMC
February 2019
2 Reads

Autoimmune progesterone dermatitis manifesting as generalized fixed drug eruption.

An Bras Dermatol 2018 Nov/Dec;93(6):874-877

Department of Pathology, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.

Autoimmune progesterone dermatitis is an uncommon, poorly recognized and under-diagnosed catamenial dermatosis associated with hypersensitivity reactions to progestagens. Most cases manifest as urticaria, eczema or erythema multiforme-like. A 26-year-old woman developed violaceous plaques on the groin and abdomen, 4 days after a spontaneous abortion resolved with uterine curettage. Read More

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http://dx.doi.org/10.1590/abd1806-4841.20187290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6256208PMC
February 2019
4 Reads

Secondary syphilis presenting as erythema multiforme in a HIV-positive homosexual man: a case report and literature review.

Int J STD AIDS 2018 Nov 27:956462418805197. Epub 2018 Nov 27.

1 Dermatology Hospital of Southern Medical University (Guangdong Provincial Dermatology Hospital), Guangzhou, China.

Early syphilis can rarely cause erythema multiforme-type eruptions as well as triggering erythema multiforme (EM). EM-like lesions in secondary syphilis are characterized by clinical features of EM and laboratory tests consistent with secondary syphilis and the skin histology shows predominantly a plasma cell infiltrate with the presence of treponemes. When EM is triggered by early syphilis, the skin histology shows mixed inflammatory cells usually in the absence of treponemes in the skin lesion. Read More

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http://dx.doi.org/10.1177/0956462418805197DOI Listing
November 2018
4 Reads

Herpes-Associated Erythema Multiforme.

JAMA Dermatol 2018 Nov 21. Epub 2018 Nov 21.

Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1001/jamadermatol.2018.3973DOI Listing
November 2018
1 Read

Treatment of oral manifestations of toxic epidermal necrolysis with low-level laser therapy in a pediatric patient.

Pediatr Dermatol 2019 Jan 26;36(1):e27-e30. Epub 2018 Nov 26.

Department of Oral Surgery and Pathology, Faculty of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Drug-induced reactions are complications associated with high mortality and significant morbidity. Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN) are examples of these conditions, which are characterized by skin and mucous lesions. Here, we report a case of a 9-year-old girl who presented with blisters associated with an extensive vesicular rash and multiple ulcerations on the lips and oral cavity. Read More

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http://doi.wiley.com/10.1111/pde.13719
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http://dx.doi.org/10.1111/pde.13719DOI Listing
January 2019
12 Reads

Erythema multiforme-like contact dermatitis caused by herbal medicine.

Contact Dermatitis 2019 Mar 9;80(3):189-190. Epub 2019 Jan 9.

Department of Dermatology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

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http://dx.doi.org/10.1111/cod.13172DOI Listing
March 2019
3 Reads

Propranolol eye drops in patients with corneal neovascularization.

Medicine (Baltimore) 2018 Nov;97(45):e13002

Pediatric Ophthalmology Unit, Niguarda Ca' Granda Metropolitan Hospital, Milan, Italy.

Rationale: Studies performed in animal models of corneal neovascularization suggested the possible efficacy of a treatment with propranolol. Corneal neovascularization is one of the most feared complications of Stevens-Johnson syndrome that frequently involves ocular surface. We report the first 2 patients with severe ocular neo-vascularization treated with different degrees of success, with propranolol eye drops. Read More

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http://Insights.ovid.com/crossref?an=00005792-201811090-0001
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http://dx.doi.org/10.1097/MD.0000000000013002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250516PMC
November 2018
16 Reads

Case of Erythema Multiforme Drug Eruption Induced by Ledipasvir/Sofosbuvir: Erratum.

Authors:

Am J Ther 2018 Nov/Dec;25(6):e784

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http://dx.doi.org/10.1097/MJT.0000000000000876DOI Listing
November 2018
1 Read

Autoimmune Progesterone Dermatitis Diagnosed by Lymphocyte Transformation Test and Progesterone Provocation Test.

Acta Dermatovenerol Croat 2018 Oct;26(3):276-277

Assoc. Prof. Suzana Ljubojević Hadžavdić, MD, PhD, Department of Dermatology and Venereology University Hospital Center Zagreb School of Medicine University of Zagreb, Šalata 4, 10000 Zagreb, Croatia;

Autoimmune progesterone dermatitis (APD) is rare autoimmune response to endogenous progesterone or to earlier exposure to exogenous progesterone (1). Skin lesions typically occur due to increases in progesterone during the luteal phase of the menstrual cycle (2). A-31-year-old mother of two children presented to our Department with a 5-year history of pruritic and painful erythematosus macules, papules, and patches on her neck, pectoral region, and face, which appeared 2-3 days before the onset of menses and gradually resolved 7-10 days later (Figure 1). Read More

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October 2018
12 Reads

Generalized bullous fixed-drug eruption secondary to the influenza vaccine.

JAAD Case Rep 2018 Oct 12;4(9):953-955. Epub 2018 Oct 12.

University of North Carolina School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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http://dx.doi.org/10.1016/j.jdcr.2018.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197945PMC
October 2018
3 Reads

Deflazacort-Induced Erythema Multiforme Exudativum Successfully Treated With a Single Dose of Etanercept.

J Investig Allergol Clin Immunol 2018 Oct;28(5):338-339

Dermatology Department Hospital Universitario de Fuenlabrada, Fuenlabrada, Spain.

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http://dx.doi.org/10.18176/jiaci.0277DOI Listing
October 2018
2 Reads

Postpartum eruption of enoxaparin-induced erythema multiforme.

Clin Case Rep 2018 Oct 23;6(10):1966-1969. Epub 2018 Aug 23.

Division of Dermatology NorthShore University HealthSystem Skokie Illinois.

Enoxaparin is a commonly used hospital medication and in rare instances may result in development of erythema multiforme. Management of these patients can be challenging. Physicians must maintain a high index of suspicion and consider the indication for enoxaparin therapy prior to withdrawal of the medication. Read More

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http://dx.doi.org/10.1002/ccr3.1752DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6186885PMC
October 2018

Erythema Multiforme Major After Immunotherapy With Diphenylcyclopropenone for Alopecia Areata.

Dermatitis 2018 Nov/Dec;29(6):348-349

MS II, Sidney Kimmel Medical College Thomas Jefferson University Philadelphia, PA Department of Dermatology, School of Medicine University of Maryland Baltimore Department of Dermatology and Cutaneous Biology Sidney Kimmel Medical College Thomas Jefferson University Philadelphia, PA

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http://dx.doi.org/10.1097/DER.0000000000000415DOI Listing
October 2018
6 Reads

[Boston Keratoprosthesis with temporal aponeurosis graft: A solution when there seems to be no more].

J Fr Ophtalmol 2018 Nov 19;41(9):830-835. Epub 2018 Oct 19.

Service d'ophtalmologie II, centre hospitalier national des Quinze-Vingts, 28, rue de Charenton, 75012 Paris, France.

Purpose: To report cases of patients with severe bilateral corneal blindness and recurrent refractory perforation to keratoplasty and conventional treatment, for whom Boston keratoprosthesis (KP) was a satisfactory alternative when combined with a temporalis aponeurosis graft.

Description Of Cases: The first patient had progressive Lyell syndrome with spontaneous corneal perforation. The second had a severe graft vs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01815512183029
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http://dx.doi.org/10.1016/j.jfo.2018.01.010DOI Listing
November 2018
13 Reads

[When drugs induce cutaneous lupus erythematosus].

Ugeskr Laeger 2018 Oct;180(41)

Drug-induced subacute cutaneous lupus erythematosus (DI-SCLE) is defined as an adverse reaction to continuous use of a culprit drug. The reaction resolves upon drug withdrawal. More than 50 drugs have been linked to DI-SCLE, and it is estimated, that around 20% of the SCLE cases are drug-induced. Read More

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October 2018
4 Reads

Bartonella henselae in a dog with ear tip vasculitis.

Vet Dermatol 2018 Dec 14;29(6):537-e180. Epub 2018 Oct 14.

Intracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, 1050 William Moore Drive, Raleigh, NC, 27607, USA.

Background: Bartonella henselae, a Gram-negative, zoonotic, alpha-proteobacteria has been previously implicated in association with cutaneous vasoproliferative lesions (bacillary angiomatosis), nodular panniculitis and multifocal erythema (erythema multiforme) in dogs.

Objective: Describe clinical, microbiological and histological lesions in a dog with ear margin vasculitis and B. henselae infection. Read More

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http://dx.doi.org/10.1111/vde.12695DOI Listing
December 2018
2 Reads

Toxic epidermal necrolysis: the red eye and red herrings in casualty.

BMJ Case Rep 2018 Oct 12;2018. Epub 2018 Oct 12.

Department of Ophthalmology, Queen Elizabeth Hospital Birmingham, Birmingham, Birmingham, UK.

A 38-year-old woman presented to casualty with bilateral red eyes associated with a recent upper respiratory tract infection. This was initially diagnosed as conjunctivitis, however systemic review revealed an erythematous facial and skin rash, mildly swollen lips and mild swallowing difficulties. The patient was referred for an urgent medical assessment, by which time she was found to have erythema affecting 54% of her body surface area and diagnosed with suspected toxic epidermal necrolysis (TEN). Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22586
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http://dx.doi.org/10.1136/bcr-2018-225861DOI Listing
October 2018
12 Reads

A Rare Case Report of Giant Cell Tumor of the Sphenoid Bone in a Patient Who Developed "Erythema Multiforme Associated with Phenytoin and Cranial Radiation Therapy Syndrome".

Asian J Neurosurg 2018 Jul-Sep;13(3):877-880

Department of Radiotherapy, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India.

Giant cell tumors (GCTs) are rare, usually affecting the epiphyses in long bones of the extremities. GCTs may be locally aggressive with a high rate of local recurrence and exhibit the potential for distant metastasis. They seldom occur in the skull, where they preferentially affect the sphenoid and temporal bones. Read More

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http://dx.doi.org/10.4103/ajns.AJNS_352_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159083PMC
October 2018
1 Read

Reasons for inpatient admissions to the dermatology department in Lomé, Togo : Trends between 1992 to 2005 and 2005 to 2016.

Med Sante Trop 2018 Aug;28(3):270-272

CHU Sylvanus Olympio, Lomé, Togo.

The aim of this study was to report the frequency of and reasons for dermatology admissions in Lomé (Togo) between 2005 and 2016. This retrospective study examined records from August 2005 to December 2016 from the dermatology departments of the two teaching hospitals in Lomé, Togo. During the study period, 454 (1. Read More

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http://dx.doi.org/10.1684/mst.2018.0813DOI Listing
August 2018
3 Reads

Treatment of Skin Reaction Induced by Nivolumab Combined with Radiotherapy in Non-small Cell Lung Cancer: A Case Report.

Chin Med Sci J 2018 Sep;33(3):183-187

Department of Oncology, Affiliated Qingdao Central Hospital of Qingdao University, Qingdao, Shandong 266042, China.

Skin reaction or dermatological toxicities induced by immunotherapy is common. It usually manifests skin rash or erythema and can be cured by skin lotion or steroid. Nivolumab, a human IgG4 programmed cell death protein 1 (PD-1) inhibitor, blocks T cells activation preventing signal and allows the immune system to clear cancer cells. Read More

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http://dx.doi.org/10.24920/31805DOI Listing
September 2018
1 Read

[Photo-induced erythema multiforme].

Hautarzt 2018 Oct;69(Suppl 1):49-51

Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr.9-11, 8037, München, Deutschland.

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http://dx.doi.org/10.1007/s00105-018-4179-5DOI Listing
October 2018

Severe hand-foot skin reaction and erythema multiforme-like lesions due to sorafenib.

Postgrad Med J 2018 Sep 17;94(1115):535-536. Epub 2018 Sep 17.

Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

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http://dx.doi.org/10.1136/postgradmedj-2018-136027DOI Listing
September 2018
1 Read

Annular Lesions: Diagnosis and Treatment.

Am Fam Physician 2018 Sep;98(5):283-291

Thomas Jefferson University Hospital, Philadelphia, PA, USA.

Annular lesions can present in a variety of diseases. Knowledge of the physical appearance and history of presentation of these skin findings can help in the diagnosis. A pruritic, annular, erythematous patch that grows centrifugally should prompt evaluation for tinea corporis. Read More

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September 2018
9 Reads

Histopathology of Hand-Foot-Mouth Disease in Adults and Criteria for Differentiation From Erythema Multiforme.

Am J Dermatopathol 2018 Sep 11. Epub 2018 Sep 11.

Department of Dermatology, University of Münster, Münster, Germany.

Background: Hand-foot-mouth disease (HFMD) is a common contagious viral infection usually affecting infants and children. Recently, literature on HFMD in adults is increasing. It has been reported that adults often present with unusual exanthems with similarities to erythema multiforme (EM). Read More

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http://dx.doi.org/10.1097/DAD.0000000000001263DOI Listing
September 2018
40 Reads

Overlap Syndrome with Rowell's Syndrome, Antiphospholipid Syndrome, Primary Sterility, and Sensorineural Hearing Loss: A Case Report, Brief Review, and Analysis of Cases of Rowell's Syndrome Reported from India and Abroad.

Indian J Dermatol 2018 Sep-Oct;63(5):418-423

Department of Dermatology, Dr. D. Y. Patil Medical College and Hospital, DPU, Pune, Maharashtra, India.

Rowell's syndrome (RS) is recognized since 1963 as a presentation of lupus erythematosus (LE) with erythema multiforme-like lesions and characteristic immunological changes. Antiphospholipid syndrome (APS) encompasses antibodies to phospholipids/phospholipid-binding cofactor proteins and/or circulating lupus anticoagulant with clinical manifestations of thrombosis such as recurrent spontaneous abortions, etc. A 32-year-old female with primary infertility since marriage (7 years) and sequential appearance, for the past 6 months, of various lupus-specific cutaneous lesions, "targetoid" lesions on palms, musculoskeletal, ocular and auditory (sensorineural hearing loss [SNHL]) complaints with positive serological profile for SMD-1, SS-A/Ro, SS-B/La, U1-snRNP, Ku, antiphospholipid and anticardiolipin antibodies, and histopathologically confirmed LE is presented as a case of concurrent overlap syndrome, RS and APS, primary infertility, and SNHL. Read More

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http://dx.doi.org/10.4103/ijd.IJD_437_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124237PMC
September 2018
12 Reads

Painful Oral Lesions.

Dent Clin North Am 2018 10 14;62(4):597-609. Epub 2018 Aug 14.

Naval Postgraduate Dental School, Bethesda, MD, USA. Electronic address:

Painful oral vesiculoerosive diseases (OVD) include lichen planus, pemphigus vulgaris, mucous membrane pemphigoid, erythema multiforme, and recurrent aphthous stomatitis. OVD lesions have an immunopathic cause. Treatment is aimed at reducing the immunologic and the following inflammatory response. Read More

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http://dx.doi.org/10.1016/j.cden.2018.06.002DOI Listing
October 2018
11 Reads

Case of Erythema Multiforme Drug Eruption Induced by Ledipasvir/Sofosbuvir.

Am J Ther 2018 Sep/Oct;25(5):e586-e587

Dermatology, The First Hospital of China Medical University, Shenyang, China.

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http://dx.doi.org/10.1097/MJT.0000000000000682DOI Listing
September 2018
8 Reads

Hemophagocytic lymphohistiocytosis presenting with annular erythema multiforme-like eruptions in a patient with angioimmunoblastic T cell lymphoma: A case report.

Exp Ther Med 2018 Sep 6;16(3):2060-2065. Epub 2018 Jul 6.

Department of Hematology and Oncology, Beijing Children's Hospital, Capital Medical University, Beijing 100045, P.R. China.

Angioimmunoblastic T cell lymphoma (AITL)-associated hemophagocytic lymphohistiocytosis (HLH) rarely occurs with annular erythema multiforme-like rashes. The present case report describes a patient who was misdiagnosed with erythema multiforme at an early stage of the disease due to annular erythema multiforme-like eruptions. However, antihistamine treatment was ineffective. Read More

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http://dx.doi.org/10.3892/etm.2018.6420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122190PMC
September 2018
3 Reads

Experience in Using Fetal Membranes: The Present and New Perspectives.

Transplant Proc 2018 Sep 13;50(7):2188-2194. Epub 2018 Mar 13.

Dr Stanisław Sakiel Burn Treatment Centre in Siemianowice Śląskie, Siemianowice Śląskie, Poland; Department of Health Science, University of Technology and Humanities in Bielsko-Biała, Bielsko-Biała, Poland.

Introduction: The placenta is an accessible source of tissues for transplantation. Placental transplants have been used in wound treatment because of the basic function of the placenta and its nutritious properties and structure.

Patients And Methods: The aim of this work is to present the clinical usage of fetal membranes, including human amnion, on the basis of the burn treatment center's experience. Read More

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http://dx.doi.org/10.1016/j.transproceed.2018.02.120DOI Listing
September 2018
24 Reads

Anti-programmed cell death-1 therapy-associated bullous disorders: a systematic review of the literature.

Melanoma Res 2018 12;28(6):491-501

Departments of Dermatology.

Bullous disorders are rare adverse events associated with anti-programmed cell death-1 (anti-PD1) therapy. This paper presents two new cases of bullous disorders under anti-PD1 therapy and systematically reviewed the literature to foster a better understanding of the presentation and pathogenesis of bullous disorders under anti-PD1. A systematic review of the literature was completed using MEDLINE, Embase, PubMed and LILACS databases. Read More

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http://dx.doi.org/10.1097/CMR.0000000000000500DOI Listing
December 2018
8 Reads

Etoricoxib-induced toxic epidermal necrolysis: A fatal case report.

Indian J Pharmacol 2018 May-Jun;50(3):139-142

Department of Pathology, MGM Medical College, Kishanganj, Bihar, India.

Cyclooxygenase inhibitors were developed in the quest of enhanced analgesic efficacy devoid of gastric side effects. High usage of etoricoxib by prescription as well as self-administered routes has led to increasing reports of side effects and adverse reactions including dermatologic reactions in 0.1%-0. Read More

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http://www.ijp-online.com/text.asp?2018/50/3/139/239056
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http://dx.doi.org/10.4103/ijp.IJP_39_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106123PMC
December 2018
17 Reads

The Role of Biological Skin Substitutes in Stevens-Johnson Syndrome: Systematic Review.

Plast Surg Nurs 2018 Jul/Sep;38(3):121-127

André Oliveira Paggiaro, PhD, is at Guarulhos University, Guarulhos, SP, Brazil. Markinokoff Lima e Silva Filho, MN, is Nursing Postgraduation Student, Programa de Pós-Graduação em Enfermagem, Guarulhos University, Guarulhos, SP, Brazil. Viviane Fernandes de Carvalho, PhD, is at Guarulhos University, Guarulhos, SP, Brazil. César Isaac, PhD, is at São Paulo University, Sao Paulo, SP, Brazil. Rolf Gemperli, PhD, is at São Paulo University, Sao Paulo, SP, Brazil.

Stevens-Johnson syndrome (SJS) is a disease that causes skin exfoliative lesions, characterized by fever, necrosis, and epidermal detachment. Biological skin substitutes may be considered interesting options for the treatment of this disease. This study aims at identifying in the literature the evidence on the current role of these biomaterials in the treatment of SJS and its related diseases. Read More

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http://dx.doi.org/10.1097/PSN.0000000000000234DOI Listing
January 2019
20 Reads

Seasonality of the hospitalizations at a dermatologic ward (2007-2017).

An Bras Dermatol 2018 Sep-Oct;93(5):755-758

Department of Dermatology and Radiotherapy, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu (SP), Brazil.

There is little data in the literature concerning dermatologic admissions. Several diseases are seasonal in incidence and clinical worsening. We performed a survey of hospitalizations in the dermatology ward of a public hospital (April/2007 to May/2017). Read More

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http://dx.doi.org/10.1590/abd1806-4841.20187309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106666PMC
October 2018
24 Reads

Erythema multiforme major with swollen lips and crusted erosions.

Lancet 2018 08 16;392(10147):592. Epub 2018 Aug 16.

Dermatology Division, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S01406736183177
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http://dx.doi.org/10.1016/S0140-6736(18)31770-7DOI Listing
August 2018
10 Reads

The effect of levamisole in the treatment of recalcitrant recurrent erythema multiforme major: An observational study.

J Dermatol Sci 2018 Oct 8;92(1):38-44. Epub 2018 Aug 8.

Whole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan; Department of Dermatology, Drug Hypersensitivity Clinical and Research Center, Chang Gung Memorial Hospital, Taipei, Linkou and Keelung, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan; Chang Gung Immunology Consortium, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan; Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan; Chang Gung Memorial Hospital, Xiamen, China. Electronic address:

Background: Erythema multiforme major (EMM) is an immune-mediated mucocutaneous eruption mostly triggered by herpes simplex virus (HSV) infection. A vicious circle of recurrence may be developed due to HSV reactivation and prolonged use of systemic corticosteroids to control EMM. Levamisole is an immunomodulator and has been applied to prevent relapses of recurrent HSV infection. Read More

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http://dx.doi.org/10.1016/j.jdermsci.2018.08.002DOI Listing
October 2018
2 Reads
3.420 Impact Factor