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    7743 results match your criteria Erythema Multiforme

    1 OF 155

    Drug-induced Rowell syndrome, a rare and difficult to manage disease: A case report.
    Exp Ther Med 2018 Jan 23;15(1):785-788. Epub 2017 Nov 23.
    Department of Ophthalmology, Grigore T. Popa University of Medicine and Pharmacy, 700715 Iași, Romania.
    Rowell syndrome is defined as the association between lupus erythematosus, erythema multiforme-like lesions and characteristic immunological changes including positive tests for rheumatoid factor, speckled antinuclear antibody, positive anti-Ro or anti-La antibodies. The present report presents the case of a 45-year-old female patient who was previously diagnosed in January 2010 with terbinafine-induced subacute cutaneous lupus erythematosus and was admitted for a skin eruption consisting of erythematous-papular erythema multiforme-like lesions, primarily on the trunk and limbs. The associated symptoms consisted of fatigability, myalgia and gonalgia. Read More

    A secondary syphilis rash with scaly target lesions.
    Oxf Med Case Reports 2018 Feb 1;2018(2):omx089. Epub 2018 Feb 1.
    Microbiologie Médicale et Infectiologie, Centre Hospitalier de l'Université de Montréal, Montréal, Canada.
    A 40-year-old man reported a 5-day history of fever and malaise, followed by a pruritic generalized rash. He had well-demarcated erythematous papules and plaques with scaling. The patient was diagnosed with secondary syphilis. Read More

    Successful drug desensitization in patients with delayed-type allergic reactions to anti-tuberculosis drugs.
    Int J Infect Dis 2018 Feb 2;68:61-68. Epub 2018 Feb 2.
    Bamrasnaradura Infectious Diseases Institute, Nonthaburi, Thailand.
    Objective: To evaluate the outcomes of anti-tuberculosis drug desensitization.

    Methods: This was a retrospective study. Inclusion criteria were as follows: age >18years, documented tuberculosis infection, a previous cutaneous allergic reaction to anti-tuberculosis drugs, and having undergone drug desensitization between January 2003 and March 2014. Read More

    [A Case of Small Intestinal GIST with Long-Term Survival after Tumor Resection for Repeated Peritoneal Recurrence].
    Gan To Kagaku Ryoho 2017 Nov;44(12):1521-1522
    Dept. of Surgery, Shiga University of Medical Science.
    A 70-year-old woman presenting with abdominal pain was admitted to our hospital. Abdominal contrast CT revealed a small intestine tumor of 10 cm with active bleeding and performed partial resection of the small intestine including tumor. Pathological findings were high risk GIST of the small intestine because of spindle cells and c-kit positive. Read More

    Stevens-Johnson syndrome/toxic epidermal necrolysis and erythema multiforme drug-related hospitalisations in a national administrative database.
    Clin Transl Allergy 2018 22;8. Epub 2018 Jan 22.
    1Basic and Clinical Immunology, Department of Pathology, Faculty of Medicine, University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.
    Background: Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) and erythema multiforme (EM) are immunologically-mediated dermatological disorders commonly triggered by drug exposure and/or other external agents. We aimed to characterise SJS/TEN- and EM-drug-related hospitalisations in a nationwide administrative database, focusing on demographic and clinical characteristics, and in the most frequently implicated drug classes.

    Methods: We analysed all drug-related hospitalisations with associated diagnosis of SJS/TEN or EM in Portuguese hospitals between 2009 and 2014. Read More

    Drug-induced oral erythema multiforme: A diagnostic challenge.
    Ann Afr Med 2018 Jan-Mar;17(1):43-45
    Department of Oral and Maxillofacial Surgery Sciences, Division of Oral Pathology and Microbiology, Najran University College of Dentistry, Najran, Saudi Arabia.
    Trimethoprim-sulfamethoxazole (cotrimoxazole or TMP/SMX) is commonly used for the treatment of urinary or lower respiratory tract infections. A comprehensive review is presented of the world literature on adverse reactions to TMP/SMX since its first use in 1968, when concern was expressed about possible hematologic toxicity. The adverse reactions to TMP/SMX occur in approximately 1%-3% of persons in general population. Read More

    Current Perspectives on Erythema Multiforme.
    Clin Rev Allergy Immunol 2018 Feb;54(1):177-184
    Unité d'allergologie, Service d'immunologie et d'allergologie, Hôpitaux Universitaires de Genève HUG, Rue Micheli-du-Crest 24, CH-1211, Genève, Switzerland.
    Recognition and timely adequate treatment of erythema multiforme remain a major challenge. In this review, current diagnostic guidelines, potential pitfalls, and modern/novel treatment options are summarized with the aim to help clinicians with diagnostic and therapeutic decision-making. The diagnosis of erythema multiforme, that has an acute, self-limiting course, is based on its typical clinical picture of targetoid erythematous lesions with predominant acral localization as well as histological findings. Read More

    Severe erythema multiforme-type drug eruption controlled by tumor necrosis factor-α antagonist: A case study.
    Exp Ther Med 2017 Dec 18;14(6):5727-5732. Epub 2017 Oct 18.
    Department of Dermatology, Suzhou Municipal Hospital, Suzhou, Jiangsu 215006, P.R. China.
    Using a tumor necrosis factor-α antagonist, the present study successfully treated a case of severe erythema multiform-type drug eruption, which occurred following anti-therapy. A 73-year-old female suffering from upper gastrointestinal bleeding and peptic-ulcer presented with an itchy rash, fever, an increase in leukocytes and eosinophils and lymphadenectasis following oral administration of amoxicillin. Following six subcutaneous injections of etanercept (initially 50 mg, then 25 mg every 3 days), the patient was deemed to have recovered. Read More

    Risperidone-induced Erythema Multiforme Minor.
    Indian J Psychol Med 2017 Nov-Dec;39(6):808-810
    Department of Psychiatry, Government Medical College, Akola, Maharashtra, India.
    Antipsychotic agents are known to cause adverse cutaneous reactions. These are supposedly rare with atypical antipsychotic agents. Adverse dermatologic reactions due to antipsychotic agent risperidone are rarely reported. Read More

    Response to: 'Human orf complicated by epidermolysis acquisita'.
    Br J Dermatol 2017 Dec 26. Epub 2017 Dec 26.
    The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.
    Dear editor, we read with great interest the article 'Human orf complicated by epidermolysis bullosa acquisita' by Zeulgaray and colleagues.Recently, a Moroccan patient who contracted orf (fig. 1a) after slaughtering a sheep during Eid Al-Adha was admitted to our hospital and developed a similar pruritic vesiculobullous eruption predominantly on the hands and forearms (fig. Read More

    Drug reaction with eosinophilia and systemic symptoms in a child on multiple antiepileptics.
    Turk J Pediatr 2017 ;59(2):197-199
    Departments of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
    Goswami JN, Vaidya PC, Saini AG, De D, Radotra BD, Singhi PD. Drug reaction with eosinophilia and systemic symptoms in a child on multiple antiepileptics. Turk J Pediatr 2017; 59: 197-199. Read More

    Cutaneous Adverse Drug Reactions in a Tertiary Care Teaching Hospital in India: An Intensive Monitoring Study.
    Indian J Dermatol 2017 Nov-Dec;62(6):618-625
    Department of Skin and VD, GMERS Medical College, Gotri, Vadodara, Gujarat, India.
    Background: The epidemiological data based on intensive monitoring studies are limited for the cutaneous adverse drug reactions (CADRs) in terms of incidence. Most of earlier Indian studies focused only on types and causative drugs of CADRs.

    Aim: The aim of this study is to analyze the CADRs with reference to the incidence, its subgroup analysis, causative drugs, and other clinical characteristics in Indian population. Read More

    Bullous Pemphigoid Masquerading as Erythema Annulare Centrifugum.
    Acta Dermatovenerol Croat 2017 Oct;25(3):255-256
    Sheng-Yiao Lin, No. 100, Tzyou 1st Road, Kaohsiung 807, Taiwan;
    Dear Editor, Bullous pemphigoid (BP), a relatively common autoimmune blistering disease in the elderly, is characterized by large, tense bullae on urticarial, erythematous, or normal skin. However, atypical BP with polymorphic clinical presentations is rarely encountered, leading to misdiagnosis and delayed treatments (1). BP with lesions resembling erythema gyratum repens or figurate erythema has been regarded as a paraneoplastic phenomenon (1). Read More

    Characteristics of pediatric recurrent erythema multiforme.
    Pediatr Dermatol 2018 Jan 12;35(1):97-103. Epub 2017 Dec 12.
    Section of Pediatric Dermatology, Departments of Dermatology and Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
    Background: Erythema multiforme (EM) is an acute condition characterized by distinctive target lesions of the skin often accompanied by mucosal ulcers. A subset of individuals experience frequent episodes of recurrent EM, which is rare and poorly understood, especially in children.

    Objective: To characterize clinical features, laboratory findings, and treatment responses of pediatric recurrent EM. Read More

    Immunohistopathological Findings of Severe Cutaneous Adverse Drug Reactions.
    J Immunol Res 2017 31;2017:6928363. Epub 2017 Oct 31.
    Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata 951-8510, Japan.
    Diagnosis of severe cutaneous adverse drug reactions should involve immunohistopathological examination, which gives insight into the pathomechanisms of these disorders. The characteristic histological findings of erythema multiforme (EM), Stevens-Johnson syndrome (SJS), and toxic epidermal necrolysis (TEN) provide conclusive evidence demonstrating that SJS/TEN can be distinguished from EM. Established SJS/TEN shows full-thickness, extensive keratinocyte necrosis that develops into subepidermal bullae. Read More

    A Review of the Effectiveness and Side-Effects of Fluocinolone Acetonide 0.1% in the Treatment of Oral Mucosal Diseases.
    Acta Stomatol Croat 2017 Sep;51(3):240-247
    Oral Medicine Department, Faculty of Dentistry Chulalongkorn University Bangkok, Thailand.
    Topical steroids have been widely used in the treatment of symptomatic oral lesions to reduce pain and inflammation. Potent topical steroids such as clobetasol propionate, fluocinolone acetonide (FA), and fluocinonide have been widely used in the treatment of severe oral mucosal lesions. Many reports have demonstrated that these steroids were effective in treating oral lesions with only minor side-effects. Read More

    Oral Manifestation in Patients diagnosed with Dermatological Diseases.
    J Contemp Dent Pract 2017 Dec 1;18(12):1153-1158. Epub 2017 Dec 1.
    Department of Oral Pathology and Microbiology, M. A. Rangoonwala College of Dental Sciences & Research Centre Pune, Maharashtra, India.
    Aim: This study aimed to estimate the frequency of oral lesions in dermatological diseased patients attending the outpatient department of Pravara Rural Medical and Dental College and Hospital, Pravara Institute of Medical Sciences (Deemed University), Loni, Ahmednagar, Maharashtra, India, and the Department of Dermatology at Medical College, Ahmednagar, Maharashtra, India.

    Materials And Methods: A cross-sectional hospital-based study was conducted in Loni from October 2013 to January 2014. A total of 310 patients (mean age 37. Read More

    Current Perspectives on Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.
    Clin Rev Allergy Immunol 2018 Feb;54(1):147-176
    Unité d'allergologie, Service d'immunologie et d'allergologie, Hôpitaux Universitaires de Genève HUG, Genève, Switzerland.
    Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are considered a delayed-type hypersensitivity reaction to drugs. They represent true medical emergencies and an early recognition and appropriate management is decisive for the survival. SJS/TEN manifest with an "influenza-like" prodromal phase (malaise, fever), followed by painful cutaneous and mucous membrane (ocular, oral, and genital) lesions, and other systemic symptoms. Read More

    Atypical Hand, Foot, and Mouth Disease Caused by Coxsackievirus A6 in Denmark: A Diagnostic Mimicker.
    Acta Derm Venereol 2017 Nov 28. Epub 2017 Nov 28.
    Department of Dermatology and Allergy Centre, Odense University Hospital, DK-5000 Odense C, Denmark.
    Since 2008, outbreaks of atypical hand, foot, and mouth disease (HFMD) in children and adults have been reported worldwide. The majority of these outbreaks are caused by a new lineage of Coxsackie virus A6 (CV-A6) presenting a more severe clinical phenotype than the classical childhood HFMD caused by CV-A16. Between June 2014 and January 2016, 23 cases of atypical HFMD disease presented at a Dermatology Department at a regional University Hospital in Denmark. Read More

    [News Skin lesions : a case report of fixed drug eruption].
    Rev Med Brux 2017 ;38(5):439-441
    Service de Gériatrie, Hôpital André Vésale, C.H.U. de Charleroi.
    Fixed drug eruption is an erythematous eruption of one or more centimetric rounded or oval lesions well demarcated, recurrent at the same place and leaving a residual purple pigmentation. Diagnosis is clinical. Skin biopsy is not essential except in doubtful cases (eg bullous drug eruption can simulate Lyell Syndrome or mucosal reminiscent of erythema multiforme). Read More

    Stevens-Johnson syndrome and toxic epidermal necrolysis: epidemiological and clinical outcomes analysis in public hospitals.
    An Bras Dermatol 2017 Sep-Oct;92(5):661-667
    Stricto Sensu Postgraduate Program In Health Sciences of Fundação de Ensino e Pesquisa em Ciências da Saúde (FEPECS) - Brasília (DF), Brazil.
    Background: Adverse drug reactions are harmful and involuntary responses to drugs that occur at doses normally used for a given condition. Among them are Stevens-Johnson syndrome and toxic epidermal necrolysis, both rare and potentially fatal conditions.

    Objectives: To analyze the epidemiological and clinical characteristics related to patients diagnosed with Stevens-Johnson syndrome and toxic epidermal necrolysis in public hospitals in the Federal District - Brazil. Read More

    [A case of Orf disease complicated by erythema multiforme].
    Arch Pediatr 2017 Dec 16;24(12):1241-1243. Epub 2017 Nov 16.
    Service d'accueil des urgences, American Memorial Hospital, CHU de Reims, 47, rue Cognacq-Jay, 51100 Reims, France.
    Ecthyma contagiosum, or Orf, is a specific infection of small ruminants accidentally reaching humans. Few cases have been reported in the literature to date. We report here a case of ecthyma contagiosum occurred in a 9-year-old girl after contact with a flock of ecthyma sheep. Read More

    Milker's nodule: an occupational infection and threat to the immunocompromised.
    J Eur Acad Dermatol Venereol 2017 Nov 10. Epub 2017 Nov 10.
    Dermatology Department, New Jersey Medical School, Rutgers University School of Public Affairs and Administration, Newark, NJ, USA.
    Milker's nodule virus, also called paravaccinia virus, is a DNA virus of the parapoxvirus genus transmitted from infected cows to humans. It results from contact with cattle, cattle by-products or fomites. Classified as an occupational disorder, those at risk of exposure include farmers, butchers and agricultural tourists. Read More

    Polymorphous Light Eruption.
    Adv Exp Med Biol 2017 ;996:61-70
    University of Genoa, Genoa, Italy.
    Polymorphous light eruption (PLE) is the commonest immuno-mediated photodermatosis. It occurs after solar or artificial UV-light exposure and affects only the sun-exposed areas with preference of the V-area of the chest, of arms and forearms, legs, upper part of the back, and rarely the face. The lesions are itching or burning, and vary morphologically from erythema to papules, vesico-papules and occasionally blisters, plaques, sometimes erythema multiforme-like, insect bite-like wheals and purpura. Read More

    Multi-system manifestations ofinfection in a young patient.
    JMM Case Rep 2017 Sep 19;4(9):e005117. Epub 2017 Sep 19.
    Infectious Diseases Unit, Department of Medicine, Sultan Qaboos University Hospital, Muscat, Oman.
    is a small cell-wall-lacking bacterium that belongs to the mycoplasma (Mollicutes) prokaryote micro-organisms. It is a common cause of both upper and lower respiratory tract infections in all age groups. Respiratory illness is the most common manifestation ofinfection; however, extrapulmonary involvement may be present or predominant. Read More

    [Acute hemorrhagic edema of infancy: alarming lesions of a benign condition. Case report].
    Arch Argent Pediatr 2017 12;115(6):e432-e435
    Salud total EPS, Urbanización El Bosque.
    We report a case of acute hemorrhagic edema of infancy in an 18-month-old boy after an episode of otitis media. The clinical presentation begins with skin erythematous macules on the thighs, followed by purpuric lesions in arms, legs, and ankle edema. It was initially interpreted as urticaria, whereby steroids were indicated. Read More

    Autoimmune Progesterone Dermatitis: A Diagnosis to Consider in a Patient With Cyclical Cutaneous Eruptions.
    J Drugs Dermatol 2017 Oct;16(10):1040-1042
    Autoimmune progesterone dermatitis (APD) is a cyclical cutaneous reaction to progesterone, with symptoms that typically begin 3-10 days before the onset of menstrual flow and end 1-2 days into menses. The symptoms vary in severity from barely visible to anaphylaxis, but most often include an eczematous eruption, erythema multiforme, urticaria, folliculitis, and angioedema. This is a rare disorder with only a handful of documented cases. Read More

    Spectrum of orocutaneous disease associations: Genodermatoses and inflammatory conditions.
    J Am Acad Dermatol 2017 Nov;77(5):809-830
    Division of Dermatology, Baylor University Medical Center, Dallas, Texas. Electronic address:
    The oral cavity and cutaneous organ systems share a close embryologic origin. Therefore, there are numerous dermatologic conditions presenting with concomitant oral findings of which the dermatologist must be aware. The second article in this continuing medical education series reviews inflammatory orocutaneous conditions and a number of genodermatoses. Read More

    The risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptic drugs.
    Epilepsia 2017 12 13;58(12):2178-2185. Epub 2017 Oct 13.
    Basel Pharmacoepidemiology Unit, Division of Clinical Pharmacy and Epidemiology, Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland.
    Objective: Older antiepileptic drugs (AEDs) are known to cause Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN). However, evidence for newer AED is sparse. We quantified risks of SJS/TEN in association with use of all AEDs in the United Kingdom. Read More

    New Evidence Supporting Cyclosporine Efficacy in Epidermal Necrolysis.
    J Invest Dermatol 2017 Oct;137(10):2047-2049
    Paris, France (retired).
    Sixty years after its original description by Sir Alan Lyell, epidermal necrolysis (from Stevens-Johnson syndrome to toxic epidermal necrolysis) seems finally amenable to a specific treatment in addition to essential symptomatic measures in specialized settings. A recently published systematic review and an article by Gonzales-Herrada et al. strongly suggest that cyclosporine is effective in reducing the risk of death. Read More

    Serum IL-17 in patients with erythema multiforme or Stevens-Johnson syndrome/toxic epidermal necrolysis drug reaction, and correlation with disease severity.
    Clin Exp Dermatol 2017 Dec 20;42(8):868-873. Epub 2017 Sep 20.
    Department of Dermatology, Venereology and Andrology , Assiut University, Egypt.
    Background: There is strong evidence that drug-induced cutaneous eruptions have an immunological component. Interleukin (IL)-17, a proinflammatory cytokine that is predominantly produced by T helper 17 cells, has been linked to various autoimmune and inflammatory diseases.

    Aim: To measure serum IL-17 levels in patients with cutaneous drug reactions [erythema multiforme (EM) and Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN)] in order to study the associations between IL-17 and disease severity. Read More

    [Targeting the skin - erythema multiforme in dogs and cats].
    Tierarztl Prax Ausg K Kleintiere Heimtiere 2017 Oct 20;45(5):352-356. Epub 2017 Sep 20.
    Teresa Böhm, Medizinische Kleintierklinik, Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München, E-Mail:
    This review article will describe the complex nature of erythema multiforme in dogs and cats. The disease pattern will be illustrated in terms of etiology, pathogenesis, clinical signs, diagnostics and therapy. Erythema multiforme is a rare, immune-mediated skin disorder with an acute specific reaction pattern of skin and mucous membranes against different underlying causes. Read More

    Minor Salivary Gland Transplantation for Severe Dry Eyes.
    Cornea 2017 Nov;36 Suppl 1:S26-S33
    *Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil; and†Department of Pathology, LIM 14, São Paulo University School of Medicine, São Paulo, Brazil.
    Dry eye is a multifactorial disease comprising a wide spectrum of ocular surface alterations and symptoms of discomfort. In most patients with aqueous-deficient dry eye, pharmaceutical tear substitutes are used to control symptoms and prevent ocular surface damage. However, in severe dry eye conditions caused by cicatricial disorders, such as Stevens-Johnson syndrome and ocular cicatricial mucous membrane pemphigoid, noninvasive treatments are insufficient, and patients are at risk of developing complications that can lead to blindness. Read More

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