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Actas Dermosifiliogr 2021 Jun 17;112(6):556-557. Epub 2021 Mar 17.

Servicio de Dermatología, Hospital Clínico Universitario de Valencia, Valencia, Spain.

BMJ Case Rep 2021 Apr 7;14(4). Epub 2021 Apr 7.

Paediatrics, Case Western Reserve University Hospital, Cleveland, Ohio, USA.

The current case report describes a 13-year-old young boy who presented with purpuric rashes following a completely asymptomatic COVID-19 infection and biopsy-confirmed leucocytoclastic vasculitis, mild haematuria and mild elevation of serum IgA. This case highlights one of the dermatological manifestations of COVID-19 infection which has not been reported so far. Paediatricians should explore the history of this infection when evaluating any child presenting with a vasculitic rash. Read More

JAAD Case Rep 2021 Apr 4;10:72-74. Epub 2021 Feb 4.

University of Texas Medical Branch, Department of Dermatology, Galveston, Texas.

Inflamm Bowel Dis 2021 05;27(6):e74-e75

Department of Medicine, Division of Gastroenterology and Hepatology, University of Illinois at Chicago, Chicago, Illinois, USA.

J Eur Acad Dermatol Venereol 2021 Jun 3;35(6):e396-e399. Epub 2021 Mar 3.

Division of Dermatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

Indian J Pediatr 2021 05 16;88(5):507-508. Epub 2021 Feb 16.

Department of Pediatrics, Bharati Vidyapeeth University Medical College Hospital & Research Centre, Pune, Maharashtra, 411043, India.

Eur Heart J 2021 05;42(18):1812

Department of Cardiology, Newham University Hospital. Glen Road, Plaistow, Barts Health NHS Trust, London, E13 8SL, UK.

BMJ Case Rep 2020 Dec 17;13(12). Epub 2020 Dec 17.

Department of Medicine, Inova Fairfax Hospital, Falls Church, Virginia, USA.

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a life-threatening condition characterised by peripheral eosinophilia, rash and multi-organ failure arising several weeks after exposure to the culprit medication. Although rare, DRESS syndrome triggered by specific agents has been associated with specific genetic polymorphisms more prevalent in different ethnic groups, including an association between dapsone-induced DRESS and Human Leukocyte Antigen (HLA)-B:13*01, a single nucleotide polymorphism more prevalent in those of Asian descent. DRESS and drug-related vasculitis may affect any organ system including the central nervous system (CNS), usually manifesting as encephalitis, meningitis or embolic cerebrovascular accidents related to eosinophilic cardiac disease and thrombosis. Read More

J Pediatr 2021 04 13;231:289-290. Epub 2020 Dec 13.

Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, Kanazawa, Japan.

Actas Dermosifiliogr 2021 Jun 9;112(6):556-557. Epub 2020 Dec 9.

Servicio de Dermatología, Hospital Clínico Universitario de Valencia, Valencia, España.

Dermatol Ther 2021 01 29;34(1):e14566. Epub 2020 Nov 29.

Dermatology Clinic, IDEA Dermatology and Dermatopathology Academy, Ankara, Turkey.

BMJ Case Rep 2020 Oct 29;13(10). Epub 2020 Oct 29.

Infectious Diseases Department, Hospital Vall d\'Hebron, Barcelona, Catalunya, Spain.

Main skin manifestations of COVID-19 have been recently classified. However, little is known about cutaneous histopathological patterns and the presence of SARS-CoV-2 in these skin lesions. We present a healthy 29-year-old man who developed a leucocytoclastic vasculitis for COVID-19 with positive SARS-CoV-2 PCR in skin biopsy. Read More

Am J Emerg Med 2021 03 28;41:266.e3-266.e5. Epub 2020 Aug 28.

Department of Dermatology, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon; Wellman Center for Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States of America.

Acute hemorrhagic edema of infancy is a benign rare presentation of leukocytoclastic vasculitis that affects children between 4 and 24 months of age. It usually involves the distal extremities, face, and ears. We report an atypical presentation of AHEI in a 1 year 5 months old boy starting initially over the trunk and back, then spreading to the face and extremities. Read More

Intern Med 2021 Feb 29;60(3):385-389. Epub 2020 Aug 29.

Department of Internal Medicine II, Shimane University Faculty of Medicine, Japan.

Anti-tumor necrosis factor (TNF) α agents, widely used for the treatment of Crohn's disease (CD), can sometimes induce skin-associated adverse events, which mainly include psoriasis-like eruptions, eczema, and cutaneous infections. In contrast, purpura caused by vasculitis is rarely seen. We herein report a unique case of leukocytoclastic vasculitis induced by infliximab administered for CD in which intermittent purpura development was noted. Read More

Clin Cosmet Investig Dermatol 2020 7;13:529-535. Epub 2020 Aug 7.

Division of Dermatology, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Erythema elevated diutinum (EED) is a rare distinctive form of cutaneous leukocytoclastic vasculitis. EED typically presents with asymptomatic symmetrical erythematous-brown papules, nodules or plaques which favor the extensor aspect of extremities while distinctly sparing the palms. We report two cases of EED with a rare presentation limited to the palms. Read More

Am J Health Syst Pharm 2020 08;77(17):1389-1392

Drake University College of Pharmacy and Health Sciences, Des Moines, IA.

Purpose: The development of leukocytoclastic vasculitis (LCV) during apixaban therapy in a female patient being treated for deep vein thrombosis (DVT) is reported.

Summary: A 74-year-old Caucasian woman weighing 102 kg presented to a walk-in clinic with complaints of mild pain and swelling in her left leg for 2 weeks. She was diagnosed as having left lower-extremity DVT. Read More

Dermatol Ther 2020 Nov 9;33(6):e14170. Epub 2020 Sep 9.

Research Unit, Fundación Piel Sana Academia Española de Dermatología y Venereología, Madrid, Spain.

A previous study has defined the maculopapular subtype of manifestations of COVID-19. The objective of our study was to describe and classify maculopapular eruptions associated with COVI-19. We carried out a subanalysis of the maculopapular cases found in the previous cross-sectional study. Read More

BMC Gastroenterol 2020 Jul 29;20(1):240. Epub 2020 Jul 29.

Mayo Clinic Family Medicine Residency - Eau Claire Program, Eau Claire, WI, USA.

Background: Leukocytoclastic vasculitis (LCV) is an immune-complex mediated vasculitis characterized by neutrophilic inflammation and nuclear debris in post capillary venules. LCV is a rare dermatologic manifestation of Crohn's disease (CD) and may occur with the onset of the disease or any time after the diagnosis including the period of exacerbation.

Case Presentation: We present a 70 year old woman with history of psoriasis and treatment refractory CD requiring monoclonal antibody therapy with ustekinumab. Read More

Dermatol Ther 2020 11 14;33(6):e14080. Epub 2020 Aug 14.

Medical Faculty, Department of Pathology, Manisa Celal Bayar University, Manisa, Turkey.

Rev Mal Respir 2020 May 28;37(5):417-421. Epub 2020 Apr 28.

Service de médecine interne et immunologie clinique, CHRU de Tours, Tours, France.

Introduction: IgA vasculitis is a leucocytoclastic vasculitis of small vessels with immune deposits of IgA. It tends to occur in a post-infectious context, though the pathogenic agent is rarely found.

Observation: We report, for the first time, the case of an 81-year old patient who presented with an acute IgA vasculitis with cutaneous and joint involvement during a Klebsiella pneumoniae respiratory infection. Read More

Rheumatology (Oxford) 2020 Apr 15. Epub 2020 Apr 15.

Department of Dermatology, Peking University First Hospital, Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, National Clinical Research Center for Skin and Immune Disease, Beijing, China.

Indian J Dermatol 2020 Mar-Apr;65(2):164-165

Department of Dermatology and Venereology, Reina Sofía Universitary Hospital, Córdoba, Spain. E-mail:

An Bras Dermatol 2020 Mar - Apr;95(2):200-202. Epub 2020 Feb 12.

Department of General Medicine, Teaching Hospital, Universidade Federal de Pelotas, Pelotas, RS, Brazil.

Erythema elevatum diutinum is a small vessel vasculitis which is benign, rare, and chronic. It is clinically characterized by violaceous, brown, or yellowish plaques, nodules, and papules. It has been associated with autoimmune, infectious, and neoplastic processes. Read More

G Ital Dermatol Venereol 2020 Mar 4. Epub 2020 Mar 4.

Section of Dermatology, Department of Medical Sciences, University of Turin, Turin, Italy.

Int J STD AIDS 2020 03;31(4):383-386

Servicio de Enfermedades Infecciosas y Tropicales - Hospital Nacional Dos de Mayo, Cercado de Lima, Peru.

Rev Esp Geriatr Gerontol 2020 May - Jun;55(3):182-183. Epub 2020 Feb 5.

Servicio de Medicina Interna, Hospital Clínico Universitario de Valladolid, Valladolid, España.

Rev Esp Geriatr Gerontol 2020 May - Jun;55(3):181-182. Epub 2019 Dec 24.

Servicio de Medicina Interna, Hospital clínico Universitario de Valladolid, Valladolid, España.

Am J Dermatopathol 2020 Jan;42(1):61-62

Pathology, Royal Liverpool and Broadgreen University Hospitals NHS trust, Liverpool, United Kingdom.

Clin Dermatol 2019 Nov - Dec;37(6):679-683. Epub 2019 Jul 31.

Department of Dermatology, University of Illinois-Chicago School of Medicine, Chicago, Illinois, USA. Electronic address:

Erythema elevatum et diutinum (EED) is a rare, chronic dermatosis. It has been associated with extracutaneous findings, including arthralgias, scleritis, panuveitis, peripheral ulcerative keratitis, oral and penile ulcers, and neuropathy. Additionally, EED is connected with various systemic diseases, including HIV, IgA paraproteinemia, myelomas, neutrophilic dermatoses, and inflammatory bowel diseases. Read More

Open Access Maced J Med Sci 2019 Sep 30;7(18):3039-3042. Epub 2019 Aug 30.

Department of Dermatology, University of Rome "G. Marconi", Rome, Italy.

Background: Erythema elevatum diutinum (EED) belongs to the spectrum of cutaneous leukocytoclastic vasculitides. EED is a very rare dermatosis presenting with reddish to browning papules and plaques. EED may be associated with infections, hematologic and autoimmune disorders. Read More