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Dermatol Pract Concept 2022 May 1;12(2):e2022077. Epub 2022 Apr 1.

Dermatology and Venereology, Private Clinic, Ankara, Turkey.

Indian J Dermatol Venereol Leprol 2022 May 4:1-3. Epub 2022 May 4.

Department of Pathology, Command Hospital, Lucknow, Uttar Pradesh, India.

J Int Med Res 2022 May;50(5):3000605221097768

Department of Internal Medicine, King Abdullah Medical City, Makkah, Kingdom of Saudi Arabia.

Leukocytoclastic vasculitis (hypersensitivity vasculitis) is defined as small blood vessel inflammation with skin or other systemic manifestations due to infections, drugs, or neoplastic disease. This clinical case report highlights an association between ceftriaxone and leukocytoclastic vasculitis in a 49-year-old female patient with a history of penicillin allergy, on mirtazapine for anxiety disorder. Articles concerning antibiotic-induced leukocytoclastic vasculitis are also reviewed. Read More

Oncology (Williston Park) 2022 05;36(5):316-320

A Mexican woman, aged 60 years, presented with fevers and abdominal pain. She had initially presented to an outside emergency department with weakness, malaise, nausea, vomiting, tachycardia to 110s, and fever to 102 °F. Her medical history was relevant for hypertension, prediabetes, and tobacco use (4-5 cigarettes/day for 12 years). Read More

Am J Dermatopathol 2022 Jul 4;44(7):523-525. Epub 2022 May 4.

Department of Dermatology, Oregon Health and Science University, Portland, OR.

Abstract: Janus kinase (JAK) inhibitors are being prescribed with increasing regularity in dermatology. We report on a patient who initiated treatment with tofacitinib for refractory erythema elevatum diutinum and subsequently developed a novel cutaneous outbreak characterized by firm violaceous papules on the trunk and extremities along with conjunctival injection and periorbital inflammation. Biopsy of affected tissue from both the cutaneous and ophthalmologic sources demonstrated increased numbers of CD30+ large atypical cells amid a mixed inflammatory cell infiltrate, consistent with lymphomatoid papulosis. Read More

BMJ Case Rep 2022 Apr 22;15(4). Epub 2022 Apr 22.

Department of Dermatology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

Granulocyte colony-stimulating factor (G-CSF) administration is associated with a diverse range of cutaneous sequelae. Serious dermatological side effects of G-CSF include the development of Sweet's syndrome and exacerbations of pre-existing inflammatory disorders such as psoriasis. Here, we describe a report of acute leucocytoclastic vasculitis caused by G-CSF therapy associated with anti-Ro and anti-La antibodies in a patient with multiple myeloma. Read More

Georgian Med News 2022 Mar(324):134-139

Städtisches Klinikum Dresden, 1Department of Dermatology and Allergology; Germany Städtisches Klinikum Dresden, 1Department of Dermatology and Allergology; Germany.

Vaccination has been the most powerful tool to fight the COVID-19 pandemic while the specific treatment options in clinical practice have been under review for approval and authorization by regulatory bodies. After registration of different vaccines, it is important to ensure a post-marketing surveillance to identify potential risks not observed in controlled trials. Authors report on the case of an 80-year-old male patient who developed severe leukocytoclastic vasculitis of skin and oral mucous membrane after receiving the second dose of COVID-19 mRNA vaccine. Read More

Cureus 2022 Jan 7;14(1):e21005. Epub 2022 Jan 7.

Dermatology Unit, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.

Neutrophilic dermatoses (ND) refer to a group of skin diseases characterized histologically by a cutaneous infiltrate of mature polymorphonuclear cells without an identifiable cause. Previously described as autonomous, these clinically distinct entities are included in the spectrum of neutrophilic disease due to the existence of overlapping forms, as described in our observation. Erythema elevatum diutinum (EED) is a rare dermatosis characterized by reddish-violaceous to browning papulonodular and plaques and belongs to the spectrum of cutaneous leukocytoclastic vasculitis. Read More

J Dermatol 2022 04 9;49(4):145-146. Epub 2022 Feb 9.

Department of Dermatology, Ruhr-University Bochum, Bochum, Germany.

J Am Geriatr Soc 2022 04 7;70(4):971-973. Epub 2022 Feb 7.

Geriatrics Unit, Hospital Central de la Cruz Roja, Madrid, Spain.

J Cutan Pathol 2022 03 4;49(3):323-326. Epub 2022 Jan 4.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida, USA.

Dermatol Ther 2022 Mar 27;35(3):e15279. Epub 2021 Dec 27.

Department of Pathology, Istanbul Medipol University Hospital, Istanbul, Turkey.

Leukocytoclastic vasculitis (LCV) is the vasculitis of small vessels. In this report, we describe a 38-year-old male patient who presented to our outpatient clinic with a 1-week history of rash on his lower extremities that had started 4 days after receiving the Pfizer-BioNTech SARS-CoV-2 vaccine. A diagnosis of LCV was made based on clinical and histopathological findings. Read More

Clin Rheumatol 2022 Jun 1;41(6):1931-1933. Epub 2021 Dec 1.

Department of Rheumatology, Yuzuncu Yıl Hospital, Ankara, Turkey.

J Cosmet Dermatol 2022 Jan 30;21(1):27-29. Epub 2021 Nov 30.

Pathology Department, Okmeydani Training and Research Hospital, Istanbul, Turkey.

Breast J 2021 12 28;27(12):895-898. Epub 2021 Nov 28.

Department of Breast Surgery, Ninewells Hospital and Medical School, Dundee, UK.

Leukocytoclastic vasculitis (LCV) is a very rare immune complex-mediated condition affecting the small vessels walls. We present the case of a 48-year-old woman with necrotizing bilateral breast LCV on treatment with glatiramer acetate for multiple sclerosis. Bilateral mastectomies and debridement of the anterior abdominal wall were required due to the rapidly evolving necrotizing process. Read More

An Bras Dermatol 2022 Jan-Feb;97(1):118-121. Epub 2021 Nov 10.

Department of Hematology, Universidade Federal de Santa Catarina, Florianópolis, SC, Brazil.

J Eur Acad Dermatol Venereol 2022 Apr 2;36(4):e316-e317. Epub 2021 Dec 2.

Department of Dermatology, Venereology and Leprology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, India.

Dermatol Ther (Heidelb) 2021 Dec 14;11(6):2235-2240. Epub 2021 Nov 14.

Department of Plastic, Aesthetic and Reconstructive Surgery, Nippon Medical School, Tokyo, Japan.

Introduction: Most severe-appearing keloids tend to occur around joints because of the increased extensional stimulation of the scar in those areas. However, erythema elevatum diutinum (EED) appears more commonly on friction sites including extensor surfaces of the extremities and dorsal surfaces of joints. EEDs also presents as red-brown and elevated lesions. Read More

Indian J Dermatol 2021 Jul-Aug;66(4):419-421

Department of Dermatology Venereology and Leprosy, Yenepoya Medical College Hospital, Yenepoya (Deemed to be University), Mangalore, Karnataka, India E-mail:

Chest 2021 11;160(5):e513-e518

Department of Medicine, Division of Pulmonary Sciences and Critical Care Medicine, University of Colorado, Aurora, CO; Department of Medicine, Division of Pulmonary and Critical Care, National Jewish Health, Denver, CO.

Case Presentation: A 56-year-old man presented to the pulmonary clinic with dyspnea and hypoxemia on exertion. He was an avid biker and skier who had noticed a significant decrease in high-level physical activity over the past 3 years. He reported dyspnea, desaturations at altitudes higher than 9,000 feet, dry cough, tachycardia, and palpitations with exercise. Read More

Cureus 2021 Sep 23;13(9):e18214. Epub 2021 Sep 23.

Dermatology, St. Joseph Dermatopathology, Houston, USA.

Erythema elevatum diutinum (EED) is a cutaneous vasculitis that is characterized by histopathologic findings of neutrophilic infiltration, vessel fibrosis, and leukocytoclasia. It most often presents as papules, plaques, and nodules on the extensor surfaces of the extremities. Herein, we present a case of a 44-year-old woman with Hashimoto's disease with an atypical presentation of EED on the palmar surface of the thumb, in addition to the classic appearance on the elbow. Read More

Vasc Med 2022 02 1;27(1):100-101. Epub 2021 Nov 1.

Vascular Health Alliance, Prisma Health, Greenville, SC, USA.

J Dermatol 2022 Jan 28;49(1):e34-e35. Epub 2021 Oct 28.

Department of Dermatology, College of Medicine, Busan Paik Hospital, Inje University, Busan, Korea.

Eur J Dermatol 2021 Oct;31(5):655-657

Division of Haematology/Oncology, Kaohsiung Veteran General Hospital, Kaohsiung, 813414, Taiwan, Division of Haematology/ Oncology, Conde S. Januário Hospital, Macau, China.

Rheumatology (Oxford) 2022 02;61(2):e43-e45

Department of Dermatology.

Am J Med Sci 2022 03 20;363(3):e21-e22. Epub 2021 Sep 20.

Department of Dermatology, 306 Hospital of PLA, Beijing, China. Electronic address:

Dermatol Ther 2021 11 5;34(6):e15141. Epub 2021 Oct 5.

Department of Dermatology, Command Hospital Air Force Bangalore, Bangalore, Karnataka, India.

With the present COVID-19 vaccination drive across the world, adverse skin reactions post COVID-19 vaccine is expected. Majority of these reactions seen were transient or local injection site reactions. However, as the larger population is being vaccinated, certain uncommon dermatological presentations including leukocytoclastic vasculitis, pityriasis rosea, and exacerbation of pre-existing autoimmune diseases are now being reported. Read More

CEN Case Rep 2022 02 17;11(1):154-158. Epub 2021 Sep 17.

Department of Nephrology, Sir Ganga Ram Hospital, Old Rajinder Nagar, New Delhi, 110060, India.

Anticoagulation-related nephropathy (ARN) is a rare form of acute kidney injury where the use of anticoagulation causes hemorrhage in various compartments of nephron including glomerulus, renal tubules, and interstitial compartment. Also, warfarin-induced vasculitis is an extremely rare condition characterized by the appearance of purpuric lesions on the skin which on biopsy are suggestive of leukocytoclastic vasculitis (LV). We hereby report a case presenting with coexistent warfarin-induced nephropathy and cutaneous vasculitis. Read More

Am J Dermatopathol 2021 Oct;43(10):755-757

Dermatology Department, Hospital de Santa Maria, Lisbon, Portugal.

J Clin Pharm Ther 2022 Apr 22;47(4):544-547. Epub 2021 Aug 22.

Department of Hematology and Pathology, Diskapi Yildirim Beyazit Training and Research Hospital, University of Health Sciences, Ankara, Turkey.

What Is Known And Objective: Primary myelofibrosis (PMF) is characterized by myeloid cell proliferation and prominent bone marrow fibrosis. Ruxolitinib, a selective inhibitor of JAK 1 and 2, significantly reduces constitutional symptoms and spleen size compared with placebo, and has significant clinical benefits in patients with myelofibrosis. The most common haematological side effects are thrombocytopenia and anaemia, and the most common non-haematological side effects are grade 1-2 diarrhoea and pyrexia. Read More