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    114 results match your criteria Erythema Dyschromicum Perstans

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    A retrospective clinico-pathological study comparing lichen planus pigmentosus with ashy dermatosis.
    Australas J Dermatol 2018 Apr 10. Epub 2018 Apr 10.
    Department of Dermatology, National Skin Centre, Singapore City, Singapore.
    Background/objectives: Controversy persists as to whether lichen planus pigmentosus and ashy dermatosis are separate clinical entities. This study was conducted to examine the clinicopathological features and treatment outcome of the two conditions.

    Methods: A retrospective medical chart review of all patients who were diagnosed with lichen planus pigmentosus or ashy dermatosis was conducted. Read More

    Erythema dyschromicum perstans in a child following an enteroviral meningitis.
    An Bras Dermatol 2017 Jan-Feb;92(1):137-138
    Pediatric Department, Centro Hospitalar do Médio Ave, Vila Nova de Famalicão, Portugal.
    A healthy 6-year-old boy presented with an erythematous macular exanthema, meningeal signs and fever, initially diagnosed with probable bacterial meningitis and treated with antibiotic and anti-inflammatory drugs. Enteroviral meningitis was confirmed, but the skin lesions continued to evolve and the patient was ultimately diagnosed with erythema dyschromicum perstans. The boy was followed during three years until the spontaneous resolution of the dermatosis. Read More

    A Case of Lichen Planus Pigmentosus with Facial Dyspigmentation Responsive to Combination Therapy with Chemical Peels and Topical Retinoids.
    J Clin Aesthet Dermatol 2016 Nov 1;9(11):44-50. Epub 2016 Nov 1.
    Residency Program Director, New York College of Osteopathic Medicine of New York Institute of Technology, Department of Dermatology, St. Barnabas Hospital, Bronx, New York.
    Lichen planus pigmentosus is a photodistributed dyschromia of unknown etiology described clinically as hyperpigmented gray-blue or brown-black macules or patches in a photodistributed pattern. Although there has been some debate, lichen planus pigmentosus is considered by many to be a separate diagnostic entity from ashy dermatosis or erythema dyschromicum perstans, which shares similar characteristics. Various treatment strategies have been applied to help resolve or improve the appearance of lichen planus pigmentosus lesions; however, an optimal treatment method is yet to be elucidated. Read More

    Coexistence of erythema dyschromicum perstans and vitiligo: a case report and review of the literature.
    Acta Dermatovenerol Alp Pannonica Adriat 2016 Dec;25(4):77-78
    Medical Park Hastanesi, Yenimahalle, Ankara, Turkey.
    Erythema dyschromicum perstans is a rare, chronic, pigmentary disorder with unknown etiology. It clinically presents with oval to round, gray, blue, or brown macules of various sizes. The etiology remains unknown; however, cobalt allergy, radio contrast media, intestinal parasites, human immunodeficiency virus, and hypothyroidism have been proposed as causative factors. Read More

    Lichen Planus Pigmentosus: The Controversial Consensus.
    Indian J Dermatol 2016 Sep-Oct;61(5):482-6
    Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India.
    A pigmented variant of lichen planus (LP) was first reported from India in 1974 by Bhutani et al. who coined the term LP pigmentosus (LPP) to give a descriptive nomenclature to it. LP has a number of variants, one of which is LPP. Read More

    Improvement of erythema dyschromicum perstans using a combination of the 1,550-nm erbium-doped fractionated laser and topical tacrolimus ointment.
    Lasers Surg Med 2017 Jan 23;49(1):60-62. Epub 2016 Aug 23.
    The Dermatology and Laser Surgery Center, Houston, Texas.
    Background And Objective: Erythema dyschromicum perstans (EDP) is a cosmetically distressing, acquired pigmentary disorder of unknown etiology for which few successful therapies exist. Herein, we present the successful use of non-ablative fractional photothermolysis in combination with topical tacrolimus ointment.

    Study Design/patients And Methods: A 35-year-old female with biopsy-confirmed EDP underwent a series of fractionated non-ablative treatment sessions utilizing the 1,550 nm erbium-doped fiber laser in combination with topical tacrolimus ointment over a period of 5 months. Read More

    Seasonal variations in dermatologic and dermatopathologic diagnoses: a retrospective 15-year analysis of dermatopathologic data.
    Int J Dermatol 2016 Oct 7;55(10):1115-8. Epub 2016 Apr 7.
    Temple University School of Medicine, Philadelphia, PA, USA.
    Background: Certain dermatologic conditions are known to show seasonal variations in frequency, the reasons for which are unclear but in some cases may be attributable to changes in ambient weather conditions.

    Objectives: The current study was conducted to determine whether seasonal trends might exist for dermatologic conditions including erythema multiforme, guttate psoriasis, erythema dyschromicum perstans (ashy dermatosis), pityriasis lichenoides, and pityriasis rosea.

    Methods: Data were derived from a 15-year retrospective review of electronic records from a large dermatopathology laboratory located in the mid-Atlantic region of the USA. Read More

    Macular pigmentation of uncertain aetiology revisited: two case reports and a proposed algorithm for clinical classification.
    Australas J Dermatol 2017 Feb 1;58(1):45-49. Epub 2016 Feb 1.
    Department of Dermatology, Fiona Stanley Hospital, Perth, Western Australia, Australia.
    Ashy dermatosis, erythema dyschromicum perstans, lichen planus pigmentosus and idiopathic eruptive macular pigmentation are various types of acquired macular hyperpigmentation disorders of the skin described in literature. However, a global consensus on the definitions of these entities is lacking. We report two cases of acquired macular (hyper)pigmentation of uncertain aetiology diagnosed as ashy dermatosis and attempt to clarify the various confusing nosologies based on existing literature. Read More

    "Melanocytic Nests Arising in Lichenoid Inflammation": Reappraisal of the Terminology "Melanocytic Pseudonests".
    Am J Dermatopathol 2015 Dec;37(12):940-3
    *Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, Boston, MA; and †Chelmsford Dermatology, P.C., Chelmsford, MA.
    Pseudonests or pseudomelanocytic nests represent aggregates of cells and cell fragments, including keratinocytes, macrophages, lymphocytes, and occasional melanocytes. Pseudomelanocytic nests in the setting of lichenoid inflammation can mimic atypical melanocytic proliferations. Several reports documented nonspecific staining of pseudonests with melanoma antigen recognized by T cells-1/Melan-A, which can be detected in the cytoplasm of nonmelanocytic cells. Read More

    Erythema Dyschromicum Perstans: Response to Topical Tacrolimus.
    Indian J Dermatol 2015 Sep-Oct;60(5):525
    Department of Dermatology, Venereology and Leprosy, Dr. R. P. Govt. Medical College, Kangra, Tanda, Himachal Pradesh, India.
    Background: Erythema dyschromicum perstans, a rare dermatosis of obscure etiopathogenesis and significant cosmetic morbidity, have no satisfactory treatment.

    Observations: Two patients with having characteristic asymptomatic and slowly progressive, slate-grey macular lesions with distinct red borders involving the face, neck, upper trunk and limbs were diagnosed clinicopathologically as erythema dyschromicum perstans. Both were treated successfully with topical tacrolimus 0. Read More

    Erythema Dyschromicum Perstans: Identical to Ashy Dermatosis or Not?
    Case Rep Dermatol 2015 May-Aug;7(2):146-50. Epub 2015 Jul 18.
    Department of Dermatology, Tokyo Medical University, Tokyo, Japan.
    Erythema dyschromicum perstans (EDP) and ashy dermatosis (AD) are pigmentary disorders of unknown etiology. EDP is usually considered to be identical to AD; however, a new clinical classification for EDP was proposed in the recent literature. Herein, we report a typical case of EDP observed in an African-American man. Read More

    Clinical and histological aspect of erythema dyschromicum perstans in Korea: A review of 68 cases.
    J Dermatol 2015 Nov 29;42(11):1053-7. Epub 2015 Jun 29.
    Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
    Erythema dyschromicum perstans (EDP) is a hypermelanotic disorder of the idiopathic variety characterized by blue-gray macules in healthy individuals. It has been described mainly in patients from tropical areas of Central and South America. Our aim was to evaluate EDP in Korea through the analysis of retrospective case series with EDP and to describe the clinical and histopathological features. Read More

    Bullous lesions in a patient with systemic lupus erythematosus.
    J Clin Aesthet Dermatol 2014 Sep;7(9):44-9
    Saratoga Dermatology, Saratoga Springs, New York.
    Bullous eruptions in patients with lupus erythematosus can be difficult to diagnose as bullous lesions can develop in lupus-specific lesions, and primary blistering disorders can also occur. Additionally, these patients tend to have multiple co-morbidities making them more likely to be on many medications that can lead to bullous drug reactions. A thorough history, the clinical presentation, and histopathological findings along with direct immunofluorescence can be helpful in diagnosing most cases. Read More

    Patch testing and histopathology in Thai patients with hyperpigmentation due to Erythema dyschromicum perstans, Lichen planus pigmentosus, and pigmented contact dermatitis.
    Asian Pac J Allergy Immunol 2014 Jun;32(2):185-92
    Institue of Dermatology-Ministry of Public Health, Bangkok, Thailand.
    Background: Erythema dyschromicum perstans (EDP)/Ashy dermatosis (AD), Lichen planus pigmentosus (LPP) and Pigmented contact dermatitis (PCD) are common skin diseases featuring abnormal pigmentation which have overlapping clinical features.

    Objective: To search for differences in the natural history, clinical features, histopathology and relevant contact allergens in patients those were clinically diagnosed as AD, LPP and PCD in our outpatient clinic.

    Method: 43 patients were enrolled into the study. Read More

    What's new in objective assessment and treatment of facial hyperpigmentation?
    Dermatol Clin 2014 Apr;32(2):123-35
    Department of Dermatology, University of Texas Southwestern Medical Center, 5939 Harry Hines Boulevard #300, Dallas, TX 75235, USA.
    Facial hyperpigmentation is common and challenging to treat in darker-skinned populations. A Medline literature search of articles published up to October 2013 reporting the objective assessment of and/or treatment for melasma, postinflammatory hyperpigmentation, dermatosis papulosa nigra, lichen planus pigmentosus, and erythema dyschromicum perstans was reviewed. Objective assessment was only reported for melasma and postinflammatory hyperpigmentation. Read More

    Acquired hyperpigmentations.
    An Bras Dermatol 2014 Jan-Feb;89(1):11-25
    Rio Grande do Sul Federal University, Child and Adolescent Health Sciences Post Graduation Program, Porto AlegreRS, Brazil, MD, Dermatologist, PhD (in course) at the Child and Adolescent Health Sciences Post Graduation Program at Rio Grande do Sul Federal University (UFRGS) - Porto Alegre (RS), Brazil.
    Cutaneous hyperpigmentations are frequent complaints, motivating around 8.5% of all dermatological consultations in our country. They can be congenital, with different patterns of inheritance, or acquired in consequence of skin problems, systemic diseases or secondary to environmental factors. Read More

    Erythema dyschromicum perstans in a Caucasian pediatric patient.
    J Drugs Dermatol 2013 Jul;12(7):819-20
    Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.
    Erythema dyschromicum perstans (EDP), or ashy dermatosis, is characterized by oval, blue-gray macules, which are completely asymptomatic. In adults, the condition is primarily seen in patients of color, most commonly those of Hispanic descent, and typically follows a chronic course. We describe a pediatric case of EDP in a Caucasian patient. Read More

    Ashy dermatosis in an 8-year-old Indian child.
    Indian Dermatol Online J 2013 Jan;4(1):30-2
    Department of Dermatology, Jawarharlal Nehru Institute of Medical Science, Porompat, Manipur, India.
    Ashy dermatosis is a disorder of pigmentation, characterized by asymptomatic symmetric ashy gray-colored macules, in the first to third decade of life. It can, however, affect children sometime. But, there is a paucity of similar cases in Indian children. Read More

    Case for diagnosis.
    An Bras Dermatol 2012 Jan-Feb;87(1):151-2
    Department of Dermatology, Hospital das Clinicas, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.
    Dyschromicum erythema perstans, or ashy dermatosis, is a rare chronic acquired skin disease characterized by gray hyperpigmented patches with erythematous borders. Its etiology is unknown and there is no specific treatment for the condition. We report a case of ashy dermatosis in a 41-year-old patient with extensive lesions on the trunk and limbs. Read More

    Lichen planus pigmentosus-inversus: case report and review of an unusual entity.
    Dermatol Online J 2012 Feb 15;18(2):11. Epub 2012 Feb 15.
    SaraPath Diagnostics, Sarasota, Florida, USA.
    Lichen planus pigmentosus-inversus is a rare variant of lichen planus, with less than 20 cases reported in the medical literature. It presents as asymptomatic to mildly pruritic, hyperpigmented macules and/or patches involving intertriginous and flexural areas and skin folds in light-skinned individuals. The unique pattern of skin involvement, clinical features, and histology are distinctive. Read More

    Erythema dyschromicum perstans in a Japanese child.
    Pediatr Dermatol 2012 Sep-Oct;29(5):637-40. Epub 2011 Nov 8.
    Department of Dermatology, Faculty of Medicine Kinki University, Osaka-Sayama, Japan.
    Erythema dyschromicum perstans (EDP) is asymptomatic slate-gray to blue-brown macules. Idiopathic eruptive macular pigmentation is asymptomatic brown nonconfluent macules. We describe electron microscopic studies of a 9-year-old Japanese girl with EDP. Read More

    Lichen planus pigmentosus-like ashy dermatosis.
    Dermatol Reports 2011 Oct 6;3(3):e46. Epub 2011 Dec 6.
    Department of Anatomopathology, University of Naples Federico II, Naples, Italy.
    Ashy dermatosis, also known as erythema dyschromicum perstans, is an idiopathic dermal melanosis of unknown etiology. We here describe an unusual case of 63-year-old Caucasian male with ashy dermatosis and skin lesion of lichen pigmentosus-like. No treatment was tried because the lesions were totally asymptomatic. Read More

    Two cases of unilateral ashy dermatosis.
    Case Rep Dermatol 2011 Jan 7;3(1):1-4. Epub 2011 Jan 7.
    Department of Dermatology, Osaka City University Graduate School of Medicine, Osaka, Japan.
    Ashy dermatosis is a typically asymptomatic disease of unknown origin that causes symmetrical gray spots to appear on the trunk and extremities. We report 2 cases of ashy dermatosis with unilateral distribution. To our knowledge, only 5 cases of ashy dermatosis with unilateral lesion have been reported so far. Read More

    Facial melanoses: Indian perspective.
    Indian J Dermatol Venereol Leprol 2011 Sep-Oct;77(5):552-63; quiz 564
    Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
    Facial melanoses (FM) are a common presentation in Indian patients, causing cosmetic disfigurement with considerable psychological impact. Some of the well defined causes of FM include melasma, Riehl's melanosis, Lichen planus pigmentosus, erythema dyschromicum perstans (EDP), erythrosis, and poikiloderma of Civatte. But there is considerable overlap in features amongst the clinical entities. Read More

    Nests with numerous SOX10 and MiTF-positive cells in lichenoid inflammation: pseudomelanocytic nests or authentic melanocytic proliferation?
    J Cutan Pathol 2011 Oct 4;38(10):797-800. Epub 2011 Aug 4.
    Department of Dermatology, Dermatopathology Section, Boston University School of Medicine, Boston, MA 02118, USA.
    Pseudomelanocytic nests in the setting of lichenoid inflammation can mimic atypical melanocytic proliferations. Both melanocytic and cytokeratin immunohistochemical stains may be utilized to differentiate these entities. Unlike true melanocytic nests, pseudomelanocytic nests contain Melanoma Antigen Recognized by T-cells 1 (MART-1)/ Melan-A-positive cells and cells positive for pan-cytokeratins, CD3 and/or CD68. Read More

    Non-ablative 1550 nm fractional laser therapy not effective for erythema dyschromicum perstans and postinflammatory hyperpigmentation: a pilot study.
    J Dermatolog Treat 2012 Oct 14;23(5):339-44. Epub 2011 Jul 14.
    Netherlands Institute for Pigment Disorders, Academic Medical Centre, University of Amsterdam, NL-1105AZ Amsterdam, The Netherlands.
    Background: Erythema dyschromicum perstans and postinflammatory hyperpigmentation (PIH) are characterized by papillary dermal pigmentation or pigment incontinence. To date, no standard treatment is available. Fractional laser therapy (FLT) was recently reported to improve different pigment disorders. Read More

    A case of Cinderella: erythema dyschromicum perstans (ashy dermatosis or dermatosis cinecienta).
    Skinmed 2011 Jan-Feb;9(1):63-4
    Department of Dermatology, Stanford School of Medicine, Stanford, CA 94305, USA.
    A 33-year-old healthy Latina (from either Mexico or Central America) woman with Fitzpatrick type V skin complained of a 2-year history of progressive hyperpigmentation on the axillary folds, dorsal hands, upper neck spilling onto the jawline area, and lower abdomen. There was no preceding dermatitis. The lesions were asymptomatic. Read More

    Erythema dyschromicum perstans.
    Dermatol Online J 2010 Nov 15;16(11):17. Epub 2010 Nov 15.
    Department of Dermatology, New York University, New York, NY, USA.
    A 39-year-old Hispanic man presented with widespread, symmetric, hyperpigmented, brown-gray-blue, oval-to-circular, discrete and coalescing patches on the upper extremities, trunk, neck and face, many with an associated annular erythematous border. Histopathologic features showed an interface dermatitis, thin lichenoid and superficial perivascular infiltrates, and dermal melanophages. These changes were consistent with a diagnosis of erythema dyschromicum perstans (EDP). Read More

    Idiopathic eruptive macular pigmentation: report on two cases.
    Indian J Dermatol 2010 Jul-Sep;55(3):277-8
    Department of Dermatology, Armed Forces Medical College, Pune, Maharashtra, India.
    Idiopathic eruptive macular pigmentation (IEMP) is a rather under-reported condition of unknown etiology. Clinically consisting of benign hyperpigmented macules, the condition is characterized histopathologically by dermal melanization. It must be differentiated from lichen planus pigmentosus, erythema dyschromicum perstans, fixed drug eruption and mastocytosis. Read More

    A case of unilateral ashy dermatosis.
    Ann Dermatol 2009 Nov 30;21(4):432-4. Epub 2009 Nov 30.
    Department of Dermatology, Busan Paik Hospital, College of Medicine, Inje University, Busan, Korea.
    Ashy dermatosis, also known as erythema dyschromicum perstans, is a peculiar, slowly progressive, idiopathic dermal melanosis. In most cases, slate gray- to lead-colored patches are symmetrically distributed over the body. Ashy dermatosis with a unilateral distribution is rare. Read More

    A Case of Idiopathic Eruptive Macular Pigmentation Limited to Flexural Areas.
    Ann Dermatol 2008 Jun 30;20(2):98-101. Epub 2008 Jun 30.
    Department of Dermatology, Ajou University School of Medicine, Suwon, Korea.
    Idiopathic eruptive macular pigmentation is a rare condition characterized by asymptomatic pigmented macules involving the neck, trunk, and proximal portions of the extremities. On histopathologic examination, there was increased pigmentation of the basal layer in otherwise normal epidermis and scattered melanophages in the papillary dermis. We report a case of a 26-year-old woman with idiopathic eruptive macular pigmentation involving only the flexural areas of the body. Read More

    Idiopathic eruptive macular pigmentation with papillomatosis: Report of nine cases.
    Indian J Dermatol Venereol Leprol 2007 Nov-Dec;73(6):402-5
    P. D. Hinduja Hospital and Medical Research Centre, Mumbai, India.
    Nine patients, seven males and two females aged 6-14 years, presented with extensive, asymptomatic, brown-black macules and mildly elevated, pigmented lesions of a few months' duration. The sites affected were the face, trunk and proximal extremities. The skin lesions were discrete and individual lesions were less than 2 cm in size. Read More

    Case reports: selected dermatoses in children of color.
    J Drugs Dermatol 2007 Jan;6(1):78-82
    George Washington University School of Medicine and Health Sciences, Washington, DC, USA.
    Three conditions, erythema dyschromicum perstans (EDP), granulomatous periorificial dermatitis (GPD), and Kawasaki disease (KD) are seen more frequently in children of color. EDP and GPD are benign and self-limited dermatoses; therapy can shorten the course of the diseases. KD, a systemic vasculitis, can have life threatening cardiac consequences and timely therapy is essential. Read More

    HLA-DR association with the genetic susceptibility to develop ashy dermatosis in Mexican Mestizo patients.
    J Am Acad Dermatol 2007 Apr 20;56(4):617-20. Epub 2006 Nov 20.
    Department of Dermatology, Hospital General Manuel Gea Gonzalez, Tlalpan, Mexico.
    Background: Ashy dermatosis, also known as erythema dyschromicum perstans, is an acquired benign disease, characterized by blue-gray pigment patches with erythematous borders. The cause is still unclear, but probably has an immunologic basis.

    Objective: The aim of this study was to determine gene frequencies of the HLA-DR alleles in Mexican patients with ashy dermatosis and compare them with ethnically matched healthy control subjects to reveal the genetic susceptibility to develop ashy dermatosis. Read More

    Immunopathologic study of erythema dyschromicum perstans (ashy dermatosis).
    Int J Dermatol 2006 Aug;45(8):937-41
    Universidad Pontificia Bolivariana, and Hospital Pablo Tobón Uribe, Medellín, Colombia.
    Erythema dyschromicum perstans (EDP) is a pigmentary disease of unknown etiology in which damage to basal cells is thought to be mediated by adhesion molecules. The aim of this study was to characterize the histopathology and immunopathology of EDP. Forty-three patients from Medellín, Colombia, with the diagnosis of EDP were evaluated. Read More

    Erythema dyschromicum perstans in children: a report of 14 cases.
    J Eur Acad Dermatol Venereol 2005 Jul;19(4):422-6
    Department of Pediatric Dermatology, Hospital del Niño Jesús, Menéndez Pelayo 65, 28009 Madrid, Spain.
    Background: Erythema dyschromicum perstans (EDP) or ashy dermatosis is a peculiar, slowly progressive, macular hyperpigmentation, which leaves a permanent discoloration. It is an acquired dermatosis that occurs most frequently in Central and South America. EDP usually appears in adults, but some isolated cases and small series have been reported in prepubertal children. Read More

    Optimal management of recalcitrant disorders of hyperpigmentation in dark-skinned patients.
    Am J Clin Dermatol 2004 ;5(3):161-8
    Department of Dermatology, University of Athens School of Medicine, Andreas Sygros Hospital for Skin and Venereal Diseases, Athens, Greece.
    Alterations in skin pigmentation may often have a dramatic expression in individuals with a dark skin complexion and can be a source of significant emotional distress in these individuals. Hyperpigmented disorders such as melanosis (melasma), post-inflammatory hyperpigmentation, drug-induced hyperpigmentation, and erythema dyschromicum perstans tend to have a prolonged course and, in many cases, are refractory to treatment, further contributing to the psychological impairment of the affected patients. Melanosis, is a common form of facial pigmentation attributable to sunlight and hormonal factors. Read More

    Erythema dyschromicum perstans: response to dapsone therapy.
    Int J Dermatol 2004 Mar;43(3):220-2
    Department of Dermatology, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
    Erythema dyschromicum perstans (EDP) is a rare disorder characterized by asymptomatic, slowly progressive, ash-gray macular pigmentation of the skin, which usually occurs from age 5 years through adult life. Most cases reported to date are of Latin American and Indian patients. Rare cases have been reported from Turkey. Read More

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