45,794 results match your criteria Erythema Ab Igne

The fetal outcomes after neoadjuvant platinum and paclitaxel chemotherapy during pregnancy: analysis of three cases and review of the literature.

Arch Gynecol Obstet 2021 Jun 11. Epub 2021 Jun 11.

Department of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, 17 Qihelou St, Dongcheng District, Beijing, 100006, China.

Objective: Data on the outcomes of fetus who are exposed to neoadjuvant platinum and paclitaxel chemotherapy during pregnancy are lacking.

Methods: Relevant data were abstracted from patients in our institution, PubMed, Embase and Cochrane Library databases. The primary assessment was the frequency of fetal death and congenital abnormalities. Read More

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Willingness-to-Pay and Benefit-Cost Analysis of Botulinum Toxin for the Treatment of Rosacea in China: Findings from a Web-Based Survey.

Patient Prefer Adherence 2021 3;15:1197-1205. Epub 2021 Jun 3.

Department of Dermatology, Xiangya Hospital, Central South University, Changsha, People's Republic of China.

Purpose: Botulinum toxin (BTX) is a new treatment approach primarily aimed at relieving flushing and erythema for rosacea, but it is expensive and lacks economic benefit evaluation studies.This study aimed to investigate willingness-to-pay (WTP) of BTX treatment and conduct benefit-cost analysis (BCA) to assess if BTX treatment for rosacea is recommendable from a viewpoint of economics in China.

Methods: WTP of BTX treatment in rosacea and information of sociodemographic and clinical characteristics were inquired via an online questionnaire among the Chinese rosacea patients. Read More

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Multiple facial candidal abscesses after self-administered acupuncture in a patient with undiagnosed diabetes mellitus: a case report.

BMC Complement Med Ther 2021 Jun 10;21(1):170. Epub 2021 Jun 10.

Department of Ophthalmology, Chungnam National University College of Medicine, Chungnam National University Hospital, #282 Munhwa-ro, Jung-gu, Daejeon, 35015, Republic of Korea.

Background: Facial abscess caused by Candida albicans infection is a rare condition even in immunocompromised patients, and only a few cases have been reported. To our knowledge, this is the first case of multiple facial candidal abscesses caused by self-administered acupuncture in an undiagnosed diabetes mellitus patient.

Case Presentation: A 57-year-old woman who had self-acupuncture treatment 2 weeks previously, presented with a 1-week history of progressive left eyelid swelling, erythema, and pain. Read More

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Optical coherence tomography quantifying photo aging: skin microvasculature depth, epidermal thickness and UV exposure.

Arch Dermatol Res 2021 Jun 10. Epub 2021 Jun 10.

Department of Dermatology, Health Sciences Faculty, Zealand University Hospital, University of Copenhagen, Sygehusvej 10, 4000, Roskilde, Denmark.

Introduction: Photo aging predominantly occurs in the face, neck and hands due to UVA and UVB irradiation. It is associated with skin cancer and histological studies indicate thinning of the epidermis and elastosis occurs. Dynamic Optical coherence tomography (D-OCT) is a non-invasive imaging tool able to visualize the epidermis and upper dermis and its blood vessels as well as to evaluate epidermal thickness (ET) and blood flow. Read More

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Clinical characteristics and predictive factors of erythema nodosum in granulomatous lobular mastitis.

Australas J Dermatol 2021 Jun 9. Epub 2021 Jun 9.

Department of Mammary Disease, The Second affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.

Background/objectives: In recent years, there is a growing incidence of granulomatous lobular mastitis (GLM), but studies about the coexistence of erythema nodosum (EN) and GLM are rare. In this study, we assess the clinical characteristics and predictive factors of EN in GLM.

Methods: A total of 303 patients diagnosed with GLM were enrolled from January 2012 to October 2018 at the second affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, including 78 patients with EN. Read More

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Analysis of the Clinical Characteristics of Dipeptidyl Peptidase-4 Inhibitor-Induced Bullous Pemphigoid.

Ann Pharmacother 2021 Jun 9:10600280211022722. Epub 2021 Jun 9.

Department of Pharmacy, The Third Xiangya Hospital, Central South University, Changsha, China.

Objective: To analyze and discuss the clinical characteristics of dipeptidyl peptidase-4 inhibitor (DPP4i)-induced bullous pemphigoid (BP).

Data Sources: We collected case reports of DPP4i-induced BP by searching databases from 2006 to mid-May 2021, as a retrospective analysis.

Study Selection And Data Extraction: Relevant case reports and case analyses of DPP4i-induced BP were included. Read More

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Very Early-Onset Inflammatory Bowel Disease (VEO-IBD) Presenting with Recurrent Leukocytoclastic Vasculitis Preceded by Streptococcal Pharyngitis.

Case Rep Pediatr 2021 20;2021:1996430. Epub 2021 May 20.

Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Nicklaus Children's Hospital, Miami, FL, USA.

Inflammatory bowel disease (IBD) that presents in children <6 years of age is known as very early-onset IBD (VEO-IBD). Extraintestinal manifestations in IBD, such as erythema nodosum (EN), pyoderma gangrenosum (PG), and, less likely, leukocytoclastic vasculitis (LV), are more commonly present in Crohn's disease. Association between LV and ulcerative colitis (UC) is not commonly seen. Read More

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Immediate nor Delayed Type Hypersensitivity Plays a Role in Late Inflammatory Reactions After Hyaluronic Acid Filler Injections.

Clin Cosmet Investig Dermatol 2021 31;14:581-589. Epub 2021 May 31.

Department of Dermatology, Amsterdam University Medical Center, Amsterdam, The Netherlands.

Purpose: The exact etiology of late inflammatory reactions (LIRs) to hyaluronic acid (HA) fillers is currently unknown. Some argue that these result from a hypersensitivity reaction, although evidence to support this is very scarce. Most reports on such reactions are not substantiated by positive skin tests. Read More

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Anesthetic management and outcomes of patients with Steven-Johnson Syndrome-A retrospective review study.

J Anaesthesiol Clin Pharmacol 2021 Jan-Mar;37(1):119-123. Epub 2021 Apr 10.

Department of Anaesthesia, MRNMSH and MRMCW, Hyderabad, Telangana, India.

Background And Aims: Steven-Johnson Syndrome (SJS) is a rare and severe form of erythema exudative multiforme. Multisystem involvement in SJS and the suspicion of precipitation of the disease with exposure to anesthetic drugs makes anesthesia a challenging task. The concerns during anesthesia are the mucosal lesions and special care that is required to prevent injury to the oropharynx and larynx during airway management and also the drugs used for anesthesia. Read More

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New use of old medicine: Nifedipine acts on the TRP family and inflammatory proteins in the treatment of chilblain.

Burns 2021 May 15. Epub 2021 May 15.

Guizhou University of Traditional Chinese Medicine, Guiyang 550025, China.

As a calcium antagonist, the mechanism of nifedipine for treating chilblain has not been reported. In the present study, we established the chilblain model by using -20 ℃ 95% ethanol to freeze the right back foot of SD rats, and investigated the effects of this drug. Hematoxylin-eosin (HE) examination indicated most of pannus in the skin tissue of chilblain rats had disappeared, and the local inflammatory cells were also greatly reduced when given nifedipine at 15. Read More

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Atypical oral candidiasis in a psoriatic patient during targeted immunotherapy with an interleukin 17 inhibitor (secukinumab).

BMC Oral Health 2021 Jun 8;21(1):292. Epub 2021 Jun 8.

Postgraduate Program in Pathology, School of Medicine, Universidade Federal Fluminense, Rio de Janeiro, Brazil.

Background: Secukinumab is a human monoclonal antibody immunoglobulin that neutralises interleukin (IL)-17A, and as such, is effective in the treatment of psoriasis. However, as IL-17A is essential in protection against fungal infections, patients treated with this drug may develop candidiasis. This report presents a case of atypical oral candidiasis occurring during targeted drug immunotherapy with an interleukin 17 (IL-17) inhibitor (secukinumab), with the aim of emphasisinge the necessity of periodical oral health assessment and monitoring. Read More

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An uncommon variant of erythema nodosum leprosum responding well to methotrexate: Report of two cases.

Trop Doct 2021 Jun 9:494755211016652. Epub 2021 Jun 9.

Professor, Department of Pathology, DR RMLH ABVIMS, New Delhi, India.

Reactions in leprosy are acute inflammatory episodes that can be classified as type I or type II. Recognition and timely management of these patients is critical to avoid permanent disability. We present two cases of erythema nodosum leprosum, presenting with recurrent atypical features, responding well to a low dose of methotrexate. Read More

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Parvovirus B19 in Pregnancy: A Case Review.

J Midwifery Womens Health 2021 Jun 8. Epub 2021 Jun 8.

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Alpert Medical School of Brown University, Providence, Rhode Island.

Parvovirus B19 has been identified as the cause of erythema infectiosum, a common childhood illness. Also known as fifth disease, this virus is highly contagious among school-age children, especially during the winter months when outbreaks within classrooms are widespread. The majority of adults have had the infection in childhood and are immune to recurrence. Read More

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Adipose Grafting for Volume and Scar Release.

Ann Plast Surg 2021 Jun;86(6S Suppl 5):S487-S490

Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.

Abstract: Adipose fat grafting (AFG) is a popular technique used to add volume in the face, breasts, and other tissue deficient areas of the body. In terms of scar release, not only has fat provided additional soft tissue coverage but also the relief of pain in scars in those patients suffering from disease processes, such as complex regional pain syndrome with steroid-induced atrophy, burn scars, morphea, and lupus. The purpose of this article is to demonstrate the senior author's technique and outcomes of using AFG in the face and body for treating volume deficiency, atrophic scarring, and deformities. Read More

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Development of a psoriatic-like skin inflammation rat model using imiquimod as an inducing agent.

Indian J Pharmacol 2021 Mar-Apr;53(2):125-131

Department of Pharmaceutical Sciences, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, Maharashtra, India.

Objective: The present investigation was undertaken to develop a psoriatic-like skin inflammation rat model using imiquimod (IMQ) as an inducing agent.

Materials And Methods: The hairs of the back dorsal portion of the Wistar rats were removed and 80, 100, and 120 mg of IMQ cream (5% w/w) for 10 consecutive days was applied to different groups of rats. Further, psoriasis area severity index was used for calculating the psoriatic score, which included scoring of erythema, scaling, and thickening. Read More

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Acute arthritis, skin rash and Lofgren's syndrome.

BMJ Case Rep 2021 Jun 7;14(6). Epub 2021 Jun 7.

Department of Radiotherapy and Oncology, IGMC, Shimla, Himachal Pradesh, India.

Sarcoidosis is an autoimmune multisystem granulomatous disorder of unknown aetiology, which mainly affects the adults in the age group of 20-39 years. The disease can affect any organ in the body but mainly presents as bilateral hilar lymphadenopathy, pulmonary infiltrates, cutaneous lesions, ocular manifestations and arthropathy. Lofgren's syndrome is an uncommon initial presentation of sarcoidosis which is recognised by the classical triad of acute arthritis, erythema nodosum and bilateral hilar lymphadenopathy. Read More

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A 70-Year-Old Man With Conspicuous Thigh Pain and ST-Segment Elevations.

Chest 2021 Jun;159(6):e403-e407

Division of Cardiovascular Medicine, University of California Davis Health System, Sacramento, CA.

Case Presentation: A 70-year-old man presented to the ED with sudden onset of left thigh pain followed by transient chest discomfort. His history included cerebrovascular disease, hypertension, and cocaine and methamphetamine use. Physical examination revealed an uncomfortable male subject with a temperature of 37 °C, heart rate of 129 beats/min, BP of 130/65 mm Hg, and 98% oxygen saturation on room air. Read More

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Cannabis induced thermal epiglottitis in a pediatric patient.

Am J Emerg Med 2021 May 13;49:114-116. Epub 2021 May 13.

Department of Pediatrics, Section on Infectious Disease, United States of America. Electronic address:

Acute epiglottitis is an airway emergency presenting with edema and inflammation of the epiglottis and aryepiglottic folds [1]. Infectious and other non-infectious etiologies may cause significant airway injury presenting with similar clinical symptoms and radiographic findings [1]. While many causes of thermal epiglottitis have been described in the pediatric and young adult population, we describe an unusual case of an adolescent patient with cannabis induced thermal epiglottitis. Read More

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Reduced expression of programmed cell death 1 and programmed cell death ligand 1 in infiltrating inflammatory cells of lichen planus without administration of immune checkpoint inhibitors.

J Dermatol 2021 Jun 7. Epub 2021 Jun 7.

Department of Dermatology, School of Medicine, Showa University, Tokyo, Japan.

Keratinocytes are the main targets of infiltrating T cells in the pathogenesis of lichen planus. However, the mechanisms of dense inflammatory infiltrates beneath the epidermis remain unknown. The aim of the present study was to clarify the roles of programmed cell death 1 (PD-1) and its ligand (PD-L1) in the pathogenesis of lichen planus. Read More

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Erythema Multiforme-like Dermatitis Due to Isoniazid Hypersensitivity in a Patient With Psoriasis.

Cutis 2021 Apr;107(4):E33-E36

Kirikkale University Faculty of Medicine, Turkey. Drs. Baççıoğlu and Kalpaklıoğlu are from the Department of Pulmonary Diseases, Division of Immunology and Allergy, and Dr. Karabulut is from the Department of Dermatology.

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Inflammatory Bowel Disease: A Gastrointestinal Presentation of Congenital Plasminogen Deficiency.

ACG Case Rep J 2021 May 2;8(5):e00613. Epub 2021 Jun 2.

Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada.

Plasminogen deficiency (PD) is a rare autosomal recessive disease that results in the formation of fibrin-rich pseudomembranes, which impair wound-healing capacity. We report a 21-year-old man with congenital PD-associated inflammatory bowel disease. After an episode of infection, he developed chronic diarrhea. Read More

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Risk Factors for Mucosal Involvement in Bullous Pemphigoid and the Possible Mechanism: A Review.

Front Med (Lausanne) 2021 20;8:680871. Epub 2021 May 20.

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Bullous pemphigoid (BP) is the most common type of autoimmune bullous disease and is characterized by the presence of circulating anti-BP180 and/or anti-BP230 autoantibodies. Patients with BP often present with tense blisters and erythema, mainly on the trunk and limbs, but a few patients also have mucosal involvement. In this article, we discuss the fact that BP patients with mucosal involvement tend to have more serious conditions and their disease is more difficult to control. Read More

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Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study.

Clin Cosmet Investig Dermatol 2021 28;14:575-580. Epub 2021 May 28.

Department of Dermatology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

Background: Localized scleroderma (LoS) is an inflammatory fibrosing disease of the connective tissue, whose esthetic sequelae are atrophic skin lesions with hyperpigmentation. The key element of diagnostic and therapeutic procedures is the assessment of the disease's severity and damage. The study objective was to analyze the usefulness of narrow-band reflectance spectrophotometry (NBRS) to assess erythema and hyperpigmentation in LoS lesions. Read More

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Tuberculosis in the paediatric age group: a reflection on transmission.

An Pediatr (Engl Ed) 2021 Jun 25;94(6):403-411. Epub 2020 Dec 25.

Servicio de Pediatría, Centro Hospitalar Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal; Centro Ambulatorio de Tuberculosis, Vila Nova de Gaia, Portugal.

Introduction: Paediatric tuberculosis (TB) disease continues to be a challenge. Difficulties in its diagnosis and limited experience on its treatment in children are some of the reasons to consider the need for specialized paediatric TB centres and to prioritize children in tuberculosis control programmes, particularly in low-incidence countries. We describe the paediatric tuberculosis cases managed in a specialized paediatric outpatient TB centre. Read More

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Light-based therapies in the management of rosacea: a systematic review with meta-analysis.

Int J Dermatol 2021 Jun 5. Epub 2021 Jun 5.

Translational Research Institute, Hamad Medical Corporation, Doha, Qatar.

Background: The current scenario and position of laser and light-based therapies (LLBT) in the therapeutic rosacea scheme are lacking evidence-based recommendations and comparisons on efficacy and tolerability among different devices. This article aimed to systematically compare the efficacy, acceptability, and tolerability of the pulsed dye laser (PDL) versus other devices.

Method: A literature search was conducted in March 2020. Read More

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Anti-Psoriatic Effects of Middle Fragment of Chlamydial Plasmid-Encoded Protein pGP3 in an Imiquimod-Induced Psoriasis Mouse Model.

Med Sci Monit 2021 Jun 5;27:e929781. Epub 2021 Jun 5.

Department of Dermatology and Venereology, Tianjin Medical University General Hospital, Tianjin, China (mainland).

BACKGROUND Previously, we demonstrated that the chlamydial protein pGP3 forms a stable complex with LL-37 to neutralize its proinflammatory activity during the pathogenesis of psoriasis. The middle domain of pGP3 (pGP3M) is critical for the binding and neutralization of LL-37. Here, we further examined the mechanism underlying pGP3-mediated inhibition of psoriasis progression and evaluated the inhibitory effect of pGP3M on the development of psoriasis-like skin lesions in mice. Read More

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Chronic Fibrosing Vasculitis: A Histologic Finding in a Case of Long-Established Erythema Elevatum Diutinum.

Actas Dermosifiliogr 2021 Jun 17;112(6):556-557. Epub 2021 Mar 17.

Servicio de Dermatología, Hospital Clínico Universitario de Valencia, Valencia, Spain.

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Study of Minimal Erythema Dose in a Series of Solar Urticaria.

Actas Dermosifiliogr 2021 Jun 1;112(6):546-550. Epub 2021 Feb 1.

Departamento de Dermatología, Hospital Universitario de La Princesa, Madrid, Spain.

Background: Reduced minimal erythema dose (MED) is an abnormal erythematous reaction to light according to the skin phototype, which is determined by phototest. MED is reduced or abnormal in some photodermatoses. However, we have not found information about reduced MED in patients with solar urticarial (SU), a condition which causes hives after sun exposure. Read More

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Possible immunoglobulin-E-dependent sugammadex-induced anaphylaxis caused by an epitope other than γ-cyclodextrin: a case report.

J Med Case Rep 2021 Jun 5;15(1):313. Epub 2021 Jun 5.

Department of Anesthesiology, Gunma University Graduate School of Medicine, Maebashi, Japan.

Background: Sugammadex is a synthetic γ-cyclodextrin derivative designed to selectively bind to steroidal neuromuscular blocking agents and reverse their effects. Although many cases of sugammadex-induced anaphylaxis have been reported, few studies have investigated the underlying mechanism.

Case Presentation: A 55-year-old Japanese man underwent a laryngectomy under general anesthesia. Read More

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Cimifugin relieves pruritus in psoriasis by inhibiting TRPV4.

Cell Calcium 2021 May 25;97:102429. Epub 2021 May 25.

School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023 China. Electronic address:

Psoriasis is an immune-mediated chronic inflammatory skin disease characterized by erythema, scales, and infiltration of the skin, which causes deleterious effects on patient quality of life. TRP channel played important roles in the generation and conductance of itch signal . According to our results, psoriasis induced itch was TRPV4 dependent, and TRPV4 expression in both epidermis and DRG were up-regulated in psoriasis. Read More

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