Cornea 2021 Jul 22. Epub 2021 Jul 22.
Department of Ophthalmology, University of Kansas, Prairie Village, KS; Department of Ophthalmology, University of Pennsylvania, Philadelphia, PA; School of Optometry, University of California, Berkeley, CA; Department of Mathematics, Cornell University, Ithaca, NY; Department of Ophthalmology, Icahn School of Medicine at Mount Sinai, New York, NY; and Department of Ophthalmology, University of Tennessee, Memphis, TN.
Purpose: The purpose of this study was to compare objective, noninvasive assessments of tear function using the OCULUS Keratograph with the corresponding clinical assessments [tear break-up time (TBUT), Schirmer test, and bulbar erythema] among patients with moderate-to-severe dry eye disease.
Methods: Participants in the Dry Eye Assessment and Management study at centers having an OCULUS Keratograph were assessed using standardized procedures. Associations between the assessments from the Keratograph [noninvasive keratograph break-up time (NIKBUT), tear meniscus height (TMH), and bulbar redness (BR)] and clinical examination (TBUT, Schirmer test, and bulbar erythema) and between these test results and Ocular Surface Disease Index (OSDI) scores were summarized with Spearman correlation coefficients (rs); 95% confidence intervals (95% CI) accounted for intereye correlation. Read More