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Int J Dermatol 2022 May 24. Epub 2022 May 24.

Department of Dermatology, University of Sfax, Sfax, Tunisia.

Background: Erysipeloid cutaneous leishmaniasis (ECL) is known as the chronic form of cutaneous leishmaniasis (CL). However, keeping its clinical presentation in view, there is a need to revisit this form of the disease.

Aims: To describe ECL in view of clinical features and treatment modalities. Read More

Clin Case Rep 2022 Feb 1;10(2):e05352. Epub 2022 Feb 1.

Dermatology Department Hedi Chaker University Hospital, University of Sfax Sfax Tunisia.

Various clinical forms of cutaneous leishmaniasis can be encountered such as: ulcerated, lupoïd, sporotrichoïd and other rare forms (eczematiform, erysipeloid, psoriasiform, verrucous, and pseudotumoral). We report an atypical presentation of verrucous and pseudotumoral cutaneous leishmaniasis that resolved following a course of cryotherapy. Read More

Microorganisms 2021 Dec 17;9(12). Epub 2021 Dec 17.

State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan 430070, China.

can cause erysipelas in animals and erysipeloid in humans. Since its recurrence in 2012, swine erysipelas has caused serious losses within the pig industry in China. The aim of this study was to perform multilocus sequence typing and understand the virulence and antimicrobial susceptibility of isolates in China. Read More

JBJS Case Connect 2021 12 15;11(4). Epub 2021 Dec 15.

Midlands Regional Hospital Tullamore, Tullamore, Offaly, Ireland.

Case: We report the case of an immunosuppressed 65-year-old man with prosthetic joint infection (PJI) 23 years postoperatively because of Erysipelothrix rhusiopathiae, through hematogenous seeding of cutaneous erysipeloid. Immunotherapy was discontinued, washout was performed, and antimicrobial therapy was guided by laboratory sensitivities. The patient was discharged on suppressive oral ciprofloxacin monotherapy. Read More

Am J Trop Med Hyg 2021 05 10;105(1):134-137. Epub 2021 May 10.

Cutaneous leishmaniasis, which is the most common form of leishmaniasis, classically presents as small erythematous papules and nodules that develop into ulcers with indurated, raised outer borders. However, lesions of cutaneous leishmaniasis can have pleomorphic and atypical presentations. The erysipeloid form is one of the rare, atypical presentations of cutaneous leishmaniasis. Read More

Pathogens 2021 Feb 1;10(2). Epub 2021 Feb 1.

School of Veterinary Medicine, Federal University of Uberlandia, Uberlandia-MG CEP 38400-902, Brazil.

Erysipelas is a disease caused by the genus, whose main species is the , the causative agent of animal erysipelas and human erysipeloid. We isolated sp. strain 2 (ES2) from turkey's organs during an outbreak in Brazilian commercial and breeder flocks with sepsis and high mortality levels. Read More

Am J Trop Med Hyg 2020 11 23;104(2):643-645. Epub 2020 Nov 23.

2Department of Pathology, National Academy of Medical Sciences, Bir Hospital, Kathmandu, Nepal.

Cutaneous leishmaniasis (CL) can present with various skin lesions ranging from a single ulcer to diffuse multiple nodules. Here, we present a case of a 67-year-old man with a large erythematous well-defined indurated plaque over the left face for a duration of 4 months. A slit skin smear was performed, and it was stained with Giemsa stain which showed multiple amastigotes confirming the diagnosis of CL. Read More

IDCases 2020 9;22:e00958. Epub 2020 Sep 9.

Department of Medicine, Staten Island University Hospital, 475 Seaview Avenue, Staten Island, New York, 10305, USA.

is a zoonotic gram positive coccobacillus. It is rarely found in humans as an occupational pathogen that mainly infects animal handlers. There are three forms of human infection: localized erysipeloid, diffuse cutaneous form and lastly, bacteremia that could progress to infective endocarditis. Read More

J Med Microbiol 2020 Oct 14;69(10):1249-1252. Epub 2020 Sep 14.

Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.

is a zoonotic pathogen that causes erysipelas in a variety of animals. In humans, in contrast to the cutaneous form called erysipeloid, which is an occupational disease and common in individuals who handle raw meat and fish, invasive systemic infections are unusual. expresses an immunogenic surface protein, Spa (surface protective antigen), which is involved in virulence. Read More

Am J Med Sci 2020 11 17;360(5):e11-e12. Epub 2020 Jul 17.

Phramongkutklao Hospital, Bangkok, Thailand.

Ann Dermatol Venereol 2020 Oct 16;147(10):676-677. Epub 2020 Jul 16.

Service de dermatologie, CHU Ibn Sina, rue Mfadel Cherkaoui, Souissi, Rabat, Maroc.

Front Vet Sci 2020 15;7:174. Epub 2020 Apr 15.

National Institute of Animal Health, National Agriculture and Food Research Organization, Tsukuba, Japan.

spp. comprise a group of small Gram-positive bacteria that can infect a variety of hosts including mammals, fish, birds, reptiles and insects. Among the eight species that have been described to date, only plays a major role in farmed livestock where it is the causative agent of erysipelas. Read More

J Dermatolog Treat 2021 Nov 8;32(7):673-683. Epub 2020 Jan 8.

Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.

Background: Old World cutaneous leishmaniasis (OWCL) is endemic in Iran and most cases of cutaneous leishmaniasis (CL) are caused by , and then and rarely by .

Objective: We aimed to describe clinical variants of OWCL and their treatments.

Method: Through literature search in PubMed, Scopus and Embase and google scholar, we have found articles about variant clinical pictures of OWCL and their treatments. Read More

BMJ Case Rep 2019 Dec 19;12(12). Epub 2019 Dec 19.

Heart and Vascular Institute, West Virginia University, Morgantown, West Virginia, USA

is a Gram-positive bacillus that is ubiquitous in nature. The bacterium is a zoonotic pathogen known to infect wild and domestic animals. Human infections, however, are uncommon and typically present with localised or generalised cutaneous lesions. Read More

IDCases 2019 29;18:e00631. Epub 2019 Aug 29.

Department of Infectious Diseases, Japanese Red Cross Wakayama Medical Center, Japan.

is a major causative organism of swine erysipelas, but the infection has rarely occurred in humans. A soft-tissue infection with this organism is described as "erysipeloid." Most reported cases in human are related to occupational exposure. Read More

Vet Dermatol 2019 Oct 31;30(5):434-e134. Epub 2019 Jul 31.

Department of Small Animal Clinical Sciences College of Veterinary Medicine, University of Florida, 2015 SW 16th Avenue, PO Box 100126, Gainesville, FL, 32611, USA.

Background: Erysipelothrix rhusiopathiae is a widespread Gram-positive, nonsporulating rod bacterium predominantly associated with skin disease in swine and cetaceans. Cutaneous lesions have yet to be described in dogs.

Objective: To describe the clinical presentation, molecular and histopathological diagnosis, and treatment of a case of erysipeloid caused by E. Read More

Res Vet Sci 2019 Jun 8;124:352-356. Epub 2019 Apr 8.

College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture, Wuhan, China; Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China. Electronic address:

Erysipelothrix rhusiopathiae is the causative agent of animal erysipelas and human erysipeloid. E. rhusiopathiae CbpB has been reported to be a protective antigen, but its pathogenic roles are not known. Read More

BMC Infect Dis 2019 Mar 25;19(1):282. Epub 2019 Mar 25.

Division of Infectious Diseases, Department of Internal Medicine, Faculty of Medicine and Dentistry, University of Alberta, 3B20-11111 Jasper Avenue, Edmonton, AB, T5K 0L4, Canada.

Background: Erysipelothrix rhusiopathiae is a zoonotic pathogen that causes erysipeloid and is most frequently associated with exposure to domestic swine. Infection of native and prosthetic joints is a rarely reported manifestation.

Case Presentation: We describe a case of E. Read More

Infect Dis Rep 2018 Nov 6;10(3):7770. Epub 2018 Nov 6.

National Centre for Tropical Infectious Diseases, Haukeland University Hospital, Bergen, Norway.

has an economic impact in animal husbandry by causing infection in swine, sheep and poultry. is present in the surface mucoid slime on fish, although fishes do not seem to be affected. Humans can get infected, maost often through occupational exposure and may suffer typical erysipeloid infection on exposed skin such as on hands and fingers, or deeper skin infections, and sometimes sepsis and endocarditis, associated with high case-fatality rate. Read More

Vaccine 2018 12 13;36(52):8079-8083. Epub 2018 Nov 13.

Animal Infectious Disease Unit, National State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture, Wuhan, China; Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China. Electronic address:

Erysipelothrix rhusiopathiae is the causative agent of animal erysipelas and human erysipeloid. Bacterial surface proteins are promising vaccine candidates. We recently identified 3 E. Read More

Vet Microbiol 2018 Nov 18;225:101-104. Epub 2018 Sep 18.

National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), 3-1-5 Kannondai, Tsukuba, Ibaraki, 305-0856, Japan; Research Institute for Biomedical Sciences, Tokyo University of Science, 2641 Yamazaki, Noda, Chiba, 278-8510, Japan. Electronic address:

Among the four species of the genus Erysipelothrix, Erysipelothrix rhusiopathiae is the main species that causes disease in swine and poultry and has also been isolated from human patients. Recently, E. rhusiopathiae infections in domesticated animals have increased in many countries and are also the cause of emerging wildlife disease in arctic and boreal ecosystems. Read More

JAAD Case Rep 2018 Oct 10;4(9):918-920. Epub 2018 Oct 10.

Division of Dermatology, Department of Medicine, University of Arizona, Tucson, Arizona.

Rev Assoc Med Bras (1992) 2018 Jun;64(6):492-497

Medical School of Valença - Rio de Janeiro, RJ, Brasil.

Erysipelatoid Carcinoma (EC), also known as Inflammatory Metastatic Carcinoma, is a rare form of cutaneous metastasis, secondary to an internal malignancy, more often related to breast cancer. Clinically, the lesion has a well-marked, bound erythematous appearance, much like an infectious process, such as erysipelas and cellulitis, these being the most common differential diagnoses. It is characterized by an acute or subacute appearance with an erythematous plaque, sometimes hot and painful, being more often situated in the primary tumor vicinity, especially in the thorax wall in the region of a mastectomy due to breast cancer. Read More

J Oncol Pharm Pract 2019 Jul 24;25(5):1271-1274. Epub 2018 Jul 24.

2 Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, USA.

Introduction: Gemcitabine is a chemotherapeutic agent used to treat several solid organ malignancies. The most common cutaneous toxicities are a mild erythematous rash and pruritus, which are often attributed to infectious etiologies. However, certain clinical characteristics may favor a drug-related reaction. Read More

Infect Immun 2018 09 22;86(9). Epub 2018 Aug 22.

National Institute of Animal Health, Tsukuba, Ibaraki, Japan

causes swine erysipelas, an infection characterized by acute septicemia or chronic endocarditis and polyarthritis. Among 17 serovars, determined based on heat-stable peptidoglycan antigens, serovars 1 and 2 are most commonly associated with the disease; however, the molecular basis for the association between these serovars and virulence is unknown. To search for the genetic region defining serovar 1a (Fujisawa) strain antigenicity, we examined the 15-kb chromosomal region encompassing a putative pathway for polysaccharide biosynthesis, which was previously identified in the Fujisawa strain. Read More

Iran J Parasitol 2017 Oct-Dec;12(4):544-553

Leishmaniasis Research Center, Kerman University of Medical Sciences, Kerman, Iran.

Background: Cutaneous leishmaniasis (CL) is associated with a broad and complex clinical spectrum of diseases. The objectives of this study were to assess the clinical features and identification of the causative agents of CL in a well-known focus of anthroponotic CL (ACL) caused by , southeast Iran.

Methods: This study was performed randomly as a descriptive cross-sectional survey to evaluate 2000 CL patients by active and passive case-detection approaches in Kerman Province from 1994 to 2014. Read More

Microb Pathog 2018 Jan 28;114:166-168. Epub 2017 Nov 28.

Animal Infectious Disease Unit, National State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture, Wuhan, China; Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China. Electronic address:

Erysipelothrix rhusiopathiae is the causative agent of animal erysipelas and human erysipeloid. E. rhusiopathiae HP0728 and HP1472 have been reported to be down regulated in low-virulence or avirulent strains, but their pathogenic roles are not known. Read More

Microb Pathog 2017 Dec 14;113:176-180. Epub 2017 Oct 14.

Animal Infectious Disease Unit, National State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan, China; College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, China; Key Laboratory of Development of Veterinary Diagnostic Products, Ministry of Agriculture, Wuhan, China; Cooperative Innovation Center for Sustainable Pig Production, Wuhan, China. Electronic address:

Erysipelothrix rhusiopathiae is the causative agent of animal erysipelas and human erysipeloid. The major protective antigen SpaA was suggested to play important roles in E. rhusiopathiae adhesion to host cells, but there is no specific study on SpaA pathogenic roles in adhesion. Read More

JAMA Oncol 2017 11;3(11):1579-1580

Division of Dermatology, University of Arizona, Tucson.