9,700 results match your criteria Erosive Pustulosis of the Scalp


Reduced prevalence of alcoholic gastritis in hospitalized individuals who consume cannabis.

Alcohol Clin Exp Res 2018 Dec 10. Epub 2018 Dec 10.

Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.

Background: Alcoholic gastritis, a superficial erosive disease of the stomach, is a common manifestation of risky alcohol use. In contrast, cannabis which is frequently co-used with alcohol suppresses gastric acidity and might counteract the deleterious effect of alcohol on the gastric mucosa. However, no clinical study has examined the impact of cannabis use on the development of alcoholic gastritis among risky alcohol users. Read More

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December 2018
1 Read

Laparoscopic sleeve gastrectomy and gastroesophageal reflux.

Rom J Intern Med 2018 Dec;56(4):227-232

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

The prevalence of obesity is rising, becoming a medical problem worldwide. Also GERD incidence is higher in obese patients compared with normal weight, with an increased risk of 2.5 of developing symptoms and erosive esophagitis. Read More

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December 2018

Evaluation of the Serum Levels of Galectin-3 in Patients with Oral Lichen Planus Disease.

Oral Dis 2018 Dec 6. Epub 2018 Dec 6.

Oral and Dental Disease Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Objectives: Galectin-3, a member of beta-galactoside-binding proteins, can be found in cytoplasm and nucleus as well as extracellularly in various tissues and involved in many physiological and pathological processes. We aimed to measure the serum levels of galectin-3 in oral lichen planus (OLP) disease and compare the result with that observed in healthy ones.

Materials And Methods: In this cross-sectional study, the serum levels of galectin-3 were measured in 56 healthy individuals and 53 pathologically proven OLP patients including those with atrophic/erosive (33 cases) or reticular (20 cases) lesions, using enzyme-linked immunosorbent assay (ELISA). Read More

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December 2018
1 Read

Association of baseline peptidylarginine deiminase 4 autoantibodies with favorable response to treatment escalation in rheumatoid arthritis.

Arthritis Rheumatol 2018 Dec 3. Epub 2018 Dec 3.

VA Nebraska-Western Iowa Health Care System, Omaha, NE, 68105.

Objective: To determine if the baseline presence of autoantibodies to peptidylarginine deiminase 4 (PAD4) predicts therapeutic response to biologic and conventional disease-modifying antirheumatic drugs (DMARDs) in patients with rheumatoid arthritis (RA) who failed methotrexate (MTX) monotherapy.

Methods: Baseline serum from 282 RA patients who failed MTX monotherapy were screened for the presence of anti-PAD4 antibodies by immunoprecipitation. Clinical response to either triple DMARD (MTX, sulfasalazine, and hydroxychloroquine) or MTX-etanercept combination therapy was determined at 24- and 48-weeks post-treatment initiation. Read More

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December 2018

Education About Dental Erosion in U.S. and Canadian Dental Schools.

J Dent Educ 2018 Dec;82(12):1296-1304

Caroline Nguyen Ngoc, DMS, MS, is Assistant Professor, Department of Restorative Dentistry, Faculté de Médecine Dentaire, Université de Montréal; and Terry E. Donovan, DDS, is Professor and Section Head for Biomaterial, Department of Operative Dentistry, University of North Carolina at Chapel Hill School of Dentistry.

Dental erosion (DE) is a well-accepted multifactorial form of tooth wear involving acids. Due to its irreversible nature, recognizing the early signs is important to develop appropriate preventive strategies. However, its place in dental curricula remains unclear. Read More

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December 2018

Opinions and Treatment Decisions for Dental Erosive Wear: A Questionnaire Survey among Icelandic Dentists.

Int J Dent 2018 1;2018:8572371. Epub 2018 Nov 1.

Nordic Institute of Dental Materials (NIOM), Oslo, Norway.

Dental erosive wear (DEW) is common among children and adolescents, and a survey of Icelandic children showed that 30.7% of 15-year-olds were diagnosed with the condition. To gain knowledge about dental practitioners' experiences, opinions, and treatment decisions. Read More

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November 2018
2 Reads

Biomarkers of erosive arthritis in systemic lupus erythematosus: Application of machine learning models.

PLoS One 2018 4;13(12):e0207926. Epub 2018 Dec 4.

Lupus Clinic, Rheumatology, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, Italy.

Objective: Limited evidences are available on biomarkers to recognize Systemic Lupus erythematosus (SLE) patients at risk to develop erosive arthritis. Anti-citrullinated peptide antibodies (ACPA) have been widely investigated and identified in up to 50% of X-ray detected erosive arthritis; conversely, few studies evaluated anti-carbamylated proteins antibodies (anti-CarP). Here, we considered the application of machine learning models to identify relevant factors in the development of ultrasonography (US)-detected erosive damage in a large cohort of SLE patients with joint involvement. Read More

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December 2018
1 Read

Erosive pustular dermatosis of the scalp associated with lamellar ichthyosis successfully treated with dehydrated human amnion/chorion membrane allograft.

JAAD Case Rep 2018 Nov 14;4(10):1059-1061. Epub 2018 Nov 14.

Department of Medicine, Division of Dermatology, University of Arizona, Tucson, Arizona.

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November 2018

Evaluation of Serum Desmoglein 1 and Desmoglein 3 in Oral Erosive Lichen Planus before and after Topical Application of Tacrolimus.

J Contemp Dent Pract 2018 Oct 1;19(10):1204-1213. Epub 2018 Oct 1.

Department of Oral Surgery, Maxillofacial and Diagnostic Science, College of Dentistry, Qassim University, KSA.

Aim: The current study will attempt to throw light on the role of desmoglein 1 and desmoglein 3 in the pathogenesis of erosive lichen planus and their response to topical application of tacrolimus.

Materials And Methods: Twenty patients with erosive oral lichen planus received tacrolimus ointment three times daily for eight weeks. Assessments using the clinical score and a visual analog scale were recorded at each visit. Read More

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October 2018
1 Read

Comparative Study of Alginate and Omeprazole in Symptomatic Treatment of Non-erosive Gastroesophageal Reflux Disease.

Mymensingh Med J 2018 Oct;27(4):771-775

Dr ANM Saifullah, Assistant Professor, Department of Gastroenterology, Sir Salimullah Medical College (SSMC), Dhaka, Bangladesh; E-mail: saifullahanm

Gastroesophageal reflux disease is widely reported most prevalent disease of the gastrointestinal tract. The burden of gastroesophageal reflux disease (GERD) is increasing in Asia and the majority of patients have non-erosive reflux disease. This prospective, open label, non random (consecutive), experimental study was performed due to compare the therapeutic efficacy of alginate and omeprazole in relieving symptoms of non erosive reflux disease (NERD) and was carried out in the Outpatient Department of Gastroenterology, Dhaka Medical College Hospital, Dhaka, Bangladesh from December 2013 to May 2014. Read More

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October 2018

Oral Administration of a Chemically Modified Curcumin, TRB-N0224, Reduced Inflammatory Cytokines and Cartilage Erosion in a Rabbit ACL Transection Injury Model.

Cartilage 2018 Nov 28:1947603518815263. Epub 2018 Nov 28.

1 The Feinstein Institute for Medical Research, Manhasset, NY, USA.

Objective: To evaluate the effects of TRB-N0224, a chemically modified curcumin (CMC) with zinc binding properties and improved pharmacokinetics, in a rabbit anterior cruciate ligament (ACL) transection injury-induced model of osteoarthritis (OA).

Design: Thirty-eight skeletally mature New Zealand white rabbits were studied in 4 groups: a sham with arthrotomy ( n = 6), control with ACL transection ( n = 6), and 2 treatment groups with ACL transection and administration of TRB-N0224 at low (25 mg/kg/day) ( n = 13) and high (50 mg/kg/day) ( n = 13) doses. After euthanization at 12 weeks, outcomes were measured by post-necropsy gross morphology, biomechanics, and cartilage and synovium histology. Read More

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November 2018

Adiponectin level changes among Egyptians with gastroesophageal reflux disease.

JGH Open 2018 Feb 28;2(1):21-27. Epub 2018 Jan 28.

Department of Internal Medicine, Faculty of Medicine AL-Azhar University Assiut Egypt.

Background And Aim: Visceral fat is an important endocrine organ that secretes different bioactive substances such as adipocytokines. The aim of this study was to investigate the adiponectin level changes among patients with erosive gastroesophageal reflux disease (GERD)and its consequence on pathogenesis.

Methods: In this study, 150 subjects were selected and divided into four groups: Group І ( = 40) were healthy individuals with an average body mass index and had no gastrointestinal tract symptoms; Group ІІ ( = 50) were patients with mild to moderate erosive esophagitis; Group ІІІ ( = 40) were patients with severe erosive esophagitis; and finally, Group ІV ( = 20) were patients with Barrett's esophagus. Read More

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February 2018
3 Reads

Erosive and crusty plaque located in the ear of a patient with a childhood burn history.

Rev Clin Esp 2018 Nov 24. Epub 2018 Nov 24.

Servicio de Dermatología, Hospital Universitario La Paz, Madrid, España.

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November 2018

Corticosteroids for septic arthritis in children.

Cochrane Database Syst Rev 2018 Nov 21;11:CD012125. Epub 2018 Nov 21.

Departamento de Pediatria, Facultad Ciencias de la Salud, Universidad del Cauca, Hospital Universitario San Jose, Departamento de Pediatría, Popayán, Cauca, Colombia, NA.

Background: Septic arthritis is an acute infection of the joints characterised by erosive disruption of the articular space. It is the most common non-degenerative articular disease in developing countries. The most vulnerable population for septic arthritis includes infants and preschoolers, especially boys. Read More

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November 2018
2 Reads

Clinical Profile of Primary Sjogrens Syndrome with Hypokalemic Periodic Paralysis.

J Assoc Physicians India 2018 May;66(5):69-70

Chief and Consultant Rheumatologist, Center for Rheumatic Diseases, Pune, Maharashtra.

Introduction: Primary Sjogren's Syndrome (pSS) with Hypokalemic Periodic Paralysis(HPP) whether an association or a different clinical subset needs review.

Methods: Cross-sectional retrospective study of subjects of Primary Sjogren's Syndrome with Hypokalemic Periodic Paralysis(HPP) identified from database maintained at Centre For Rheumatic Diseases, Pune since 1996 with records of over 50000 patients. The diagnosis was clinical. Read More

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May 2018
5 Reads

Anaemia in Newly Diagnosed Patients of Rheumatoid Arthritis and its Correlation with Disease Activity.

J Assoc Physicians India 2018 May;66(5):26-29

Senior Professor, Department of Medicine, SMS Medical College, Jaipur, Rajasthan.

Method: Fifty nine patients of RA fulfilling 2010 ACR/EULAR criteria of RA having disease duration less than two years were included in the study. Haemoglobin (Hb) levels were measured. Disease activity was assessed by DAS-28 score. Read More

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Adding Acotiamide to Gastric Acid Inhibitors Is Effective for Treating Refractory Symptoms in Patients with Non-erosive Reflux Disease.

Dig Dis Sci 2018 Nov 21. Epub 2018 Nov 21.

Department of Gastroenterology and Hepatology, Shimane University Hospital, 89-1 Enyacho, Izumo, Shimane, 693-0021, Japan.

Background: Approximately 30% of patients who are treated with proton pump inhibitors (PPIs) for gastroesophageal reflux disease (GERD) experience persistent symptoms. No prokinetic agent regiments are useful for symptom relief.

Aims: This study was conducted to examine the effect of adding acotiamide to PPI or vonoprazan refractory GERD. Read More

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November 2018
4 Reads

Gastroesophageal Reflux in Asymptomatic Patients with Diabetes: An Impedance Study Diabetes, Obesity and Gastroesophageal Reflux.

Exp Clin Endocrinol Diabetes 2018 Nov 20. Epub 2018 Nov 20.

Division of Gastroenterohepatology, Department of Internal Medicine, Istanbul University, Istanbul Faculty of Medicine.

Introduction: Gastroesophageal reflux disease (GERD) is more frequent in patients with diabetes mellitus (DM).The aim of the present study was to evaluate GER in asymptomatic patients with DM using 24-h pH impedance.

Materials And Methods: 19 healthy controls and 35 patients with DM without typical GERD symptoms were enrolled in the study. Read More

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November 2018
9 Reads

The overlap syndrome of urticaria and gastroesophageal reflux disease.

PLoS One 2018 20;13(11):e0207602. Epub 2018 Nov 20.

Aggregate Post Graduate School in Allergology and Clinical Immunology of Campania University L. Vanvitelli, Naples, Italy and of Federico II University, Naples, Italy.

Background: One-quarter of systemic symptoms associated with chronic spontaneous urticaria (CSU) are related to gastrointestinal complaints (GICs).

Objectives: To investigate the prevalence and features of urticaria-overlapping GICs.

Methods: In this retrospective cross-sectional survey, 1426 consecutive outpatients were observed at our University Department. Read More

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November 2018
3 Reads

CHRONIC ULCERATIVE STOMATITIS: a comprehensive review and proposal for diagnostic criteria.

Oral Dis 2018 Nov 20. Epub 2018 Nov 20.

Department of Dermatology, Medical University of Warsaw, Poland.

Chronic ulcerative stomatitis (CUS) is an immune-mediated disorder characterized by oral erosions and ulcers usually refractory to conventional treatments. The disease often involves middle-aged and older women with painful lesions sometimes resembling those of erosive oral lichen planus (OLP). The most affected sites are the buccal mucosa, the gingiva and the tongue, but the skin is involved in 22. Read More

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November 2018
6 Reads

Circulating exosomes regulate T-cell-mediated inflammatory response in oral lichen planus.

J Oral Pathol Med 2018 Nov 17. Epub 2018 Nov 17.

The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.

Background: Exosomes are newly recognized natural nanocarrier and intercellular messenger that emerge as important mediators of signal transmission. Exosomes have been reported to modulate the inflammatory response of a number of diseases. This study investigated the effects of circulating exosomes from oral lichen planus (OLP) on T cells. Read More

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November 2018
3 Reads

Progressive annular verrucous erosive plaques on the face.

Clin Exp Dermatol 2018 Nov 16. Epub 2018 Nov 16.

Dermatology Department, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

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November 2018
1 Read

Do fluoride toothpastes have similar preventive effect in permanent and deciduous teeth against erosive tooth wear?

Int J Paediatr Dent 2018 Nov 15. Epub 2018 Nov 15.

Department of Preventive, Restorative and Pediatric Dentistry, University of Bern, Bern, Switzerland.

Background: Little is known about fluoride toothpastes effect on deciduous teeth submitted to erosive tooth wear OBJECTIVES: To evaluate the preventive effect of different toothpastes on surface loss (SL) after severe erosion/abrasion model and to compare this effect between permanent (PT) and deciduous teeth (dt).

Design: Enamel samples were randomly divided according toothpastes groups (n=17). G1: placebo; G2: NaF; G3: AmF-NaF-SnCl anti-erosion; G4: SnF ; and G5: NaF anti-erosion for children. Read More

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November 2018
9 Reads

A Familial Case of Multicentric Carpotarsal Osteolysis Syndrome and Treatment Outcome.

J Pediatr Genet 2018 Dec 16;7(4):174-179. Epub 2018 Jun 16.

Department of Genetics, University of Alabama at Birmingham, Birmingham, Alabama, United States.

Multicentric carpotarsal osteolysis syndrome (MCTO) is a rare skeletal disorder caused by heterozygous mutations in the gene (v-maf musculoaponeurotic fibrosarcoma oncogene ortholog B). This is an autosomal dominant condition with a high frequency of sporadic cases. MCTO is characterized by osteolysis of the carpal, metacarpal, and tarsal bones beginning in early childhood with musculoskeletal rheumatologic symptoms such as pain and disability. Read More

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December 2018
4 Reads

Deregulated phospholipase D2/mammalian target of rapamycin/hypoxia-inducible factor 1 alpha in peripheral T lymphocytes of oral lichen planus correlated with disease severity.

Arch Oral Biol 2018 Nov 3;98:26-31. Epub 2018 Nov 3.

The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, PR China; Department of Oral Medicine, School and Hospital of Stomatology, Wuhan University, PR China. Electronic address:

Objective: Oral lichen planus (OLP) is a common T lymphocyte-mediated autoimmune disease of unknown etiology. The mammalian target of rapamycin (mTOR) can regulate proliferation, apoptosis, and autophagy of T lymphocytes, therefore impacting the T lymphocyte-mediated immunity. The present study was aimed to investigate the possible association between Akt/mTOR/4E-BP1 (eIF4E-binding protein 1) signaling, phospholipase D (PLD) and hypoxia-inducible factor 1 alpha (Hif-1α) in peripheral T lymphocytes of OLP and the correlation of their expression with the disease severity. Read More

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November 2018
3 Reads

α-enolase is an antigenic target in primary Sjögren's syndrome.

Clin Exp Rheumatol 2018 Nov 8. Epub 2018 Nov 8.

Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.

Objectives: Although anti-cyclic citrullinated peptides antibodies are specific markers for rheumatoid arthritis (RA), they might be present in other diseases. Our aim was to assess the native or citrullinated antigens recognised by patients with primary Sjögren's syndrome (pSS) and to evaluate their association with clinical and serological features.

Methods: In an initial screening, we assessed the serum reactivity of 12 patients with pSS against native or in vitro citrullinated antigens of HEp-2 cells by immunoblotting. Read More

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November 2018
4 Reads

Immunohistochemical Features of Different Types of Unstable Atherosclerotic Plaques of Coronary Arteries.

Bull Exp Biol Med 2018 Nov 12;166(1):102-106. Epub 2018 Nov 12.

Institute of Molecular Pathology and Pathomorphology, Federal Research Center of Fundamental and Translational Medicine, Novosibirsk, Russia.

We performed a complex morphological study of samples of different types of unstable atherosclerotic plaques obtained from 33 men with occlusive coronary atherosclerosis, who underwent coronary artery endarterectomy during coronary artery bypass surgery. In the samples, expression of MMP-2 and MMP-9, collagen IV, CD31, CD34, factor VIII, and actin of smooth muscle cells was evaluated by morphometric and immunohistochemical methods. The maximum expression of MMP-9 was found in unstable plaques of the lipid type, where it 1. Read More

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November 2018
1 Read

Evaluation of a clinical preventive treatment using Er,Cr:YSGG (2780 nm) laser on the susceptibility of enamel to erosive challenge.

Lasers Med Sci 2018 Nov 10. Epub 2018 Nov 10.

Department of Operative Dentistry, School of Dentistry, Aristotle University of Thessaloniki, 54124, Thessaloniki, Greece.

The purpose of this in vitro study was to evaluate the effect of a clinical preventive treatment using Er,Cr:YSGG laser irradiation on bovine enamel susceptibility after erosive challenge. Twelve sound bovine incisors were used and twenty-four enamel specimens were prepared in total. Two experimental groups (n = 12) were assigned as follows: Group 1 was the control group and in Group 2, the enamel specimens were irradiated with an Er,Cr:YSGG (2780 nm) laser system for 20 s, with average output power of 0. Read More

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November 2018
4 Reads

Hydroxychloroquine sulphate therapy of erosive oral lichen planus.

Australas J Dermatol 2018 Nov 8. Epub 2018 Nov 8.

Department of Dermatology, Rambam Medical Center, Haifa, Israel.

Background/objectives: Erosive oral lichen planus (LP) may be painful and debilitating. Symptomatic oral LP has been treated with a wide spectrum of topical and systemic therapies, but few have been evaluated in large series. Hydroxychloroquine is suggested to be effective in oral LP. Read More

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November 2018
3 Reads

Chronic Crusted Scalp Lesion of an Elderly Male.

Skin Appendage Disord 2018 Oct 21;4(4):354-357. Epub 2017 Dec 21.

Pathology and Laboratory Medicine Service, James A. Haley VA Hospital, Tampa, Florida, USA.

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October 2018
6 Reads

Oral health among Dutch elite athletes prior to Rio 2016.

Phys Sportsmed 2018 Nov 8:1-7. Epub 2018 Nov 8.

a Department of Oral & Maxillofacial Surgery , Special Dental Care and Orthodontics, Erasmus Medical Centre , Rotterdam , The Netherlands.

Objectives: Elite athletes are at high risk for poor oral health. A screening program to assess oral health and create dental awareness can improve oral health among elite athletes but has not been performed in the Netherlands before. We summarize the first results from such a screening conducted in Dutch elite athletes of the Nederlands Olympisch Committee*Nederlandse Sport Federatie (NOC*NSF, Dutch Olympic Committee). Read More

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November 2018

Medial Orbital Wall Reconstruction to Facilitate Endoscopic Sinus Surgery for Erosive Polypoidal Sinus Disease.

Ophthalmic Plast Reconstr Surg 2018 Nov 5. Epub 2018 Nov 5.

Department of Ophthalmology and Visual Science.

The authors report the use of a 0.35-mm-thickness nylon implant for medial orbital wall reconstruction to facilitate functional endoscopic sinus surgery (FESS) for severe erosive polypoidal sinus disease while minimizing iatrogenic injuries to the orbital contents. A retrospective chart review identified 4 patients with extensive polypoidal sinus disease who underwent medial orbital wall reconstruction in the setting of FESS. Read More

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November 2018
2 Reads

Ankylosing Spondylitis Manifested by Extensive Cervical Erosions with Spontaneous Anterior Atlantoaxial Subluxation.

World Neurosurg 2018 Nov 4. Epub 2018 Nov 4.

Department of Orthopaedic Surgery, Changzheng Hospital, Shanghai, China. Electronic address:

Purpose: We present a rare case of atlantoaxial instability as a result of bone erosions in a patient with ankylosing spondylitis and review the literature. We describe the radiographic characters, pathology and treatment of the case, hoping to shed light on the rare clinical manifestation.

Methods: We present a case of a 36-year-old male with an 8-year history of ankylosing spondylitis with a progressive neck pain, low back pain, hand numbness and motion limitation of neck. Read More

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November 2018
3 Reads

Mechanical strain determines the site-specific localization of inflammation and tissue damage in arthritis.

Nat Commun 2018 11 5;9(1):4613. Epub 2018 Nov 5.

Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Technologiepark 927, 9052, Ghent, Belgium.

Many pro-inflammatory pathways leading to arthritis have global effects on the immune system rather than only acting locally in joints. The reason behind the regional and patchy distribution of arthritis represents a longstanding paradox. Here we show that biomechanical loading acts as a decisive factor in the transition from systemic autoimmunity to joint inflammation. Read More

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November 2018
6 Reads

[Gastroesophageal reflux disease is associated with high risk of obstructive sleep apnea syndrome].

Zhonghua Nei Ke Za Zhi 2018 Nov;57(11):824-829

Department of Gastroenterology, The Central Hospital of Longhua District, Shenzhen 518110, China.

To investigate the relationship between gastroesophageal reflux disease (GERD) and obstructive sleep apnea syndrome(OSAS). Patients diagnosed as GERD and healthy controls without GERD related symptoms or endoscopic esophagitis were enrolled from October 2017 and December 2017. All subjects completed Berlin Questionaire to assess the risk of OSAS. Read More

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November 2018
4 Reads

Dual Delayed-Release Dexlansoprazole for Healing and Maintenance of Healed Erosive Esophagitis: A Safety Study in Adolescents.

Dig Dis Sci 2018 Nov 2. Epub 2018 Nov 2.

Takeda Development Center Americas, Inc, Deerfield, IL, USA.

Background: In gastroesophageal reflux disease (GERD), the frequency of heartburn symptoms and erosive esophagitis (EE) increases with age in children and adolescents. Proton pump inhibitor, dexlansoprazole, is approved for healing EE of all grades, maintenance of healed EE, relief of heartburn, and treatment of symptomatic non-erosive GERD in patients ≥ 12 years.

Aim: To assess safety and efficacy of dexlansoprazole dual delayed-release capsule in healing of EE and maintenance of healed EE in adolescents. Read More

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November 2018
2 Reads

Diflunisal tolerability in transthyretin cardiac amyloidosis: a single center's experience.

Amyloid 2018 Sep 2;25(3):197-202. Epub 2018 Nov 2.

a Department of Cardiovascular Medicine , Cleveland Clinic Foundation , Cleveland , OH , USA.

Objective: Transthyretin (ATTR) amyloidosis is an under-recognized, progressive disease manifesting as cardiomyopathy and/or polyneuropathy. Diflunisal, a nonsteroidal anti-inflammatory drug (NSAID), has demonstrated transthyretin stabilization in vitro and slowing of polyneuropathy progression in the hereditary ATTR subtype (ATTRm). However, the use of diflunisal has only been described in a small cohort of patients with ATTR cardiac amyloidosis (CA). Read More

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September 2018
6 Reads
2.010 Impact Factor

Prevalence and Associated Risk Factors of Tooth Wear.

JNMA J Nepal Med Assoc 2018 Jul-Aug;56(212):719-723

Department of Conservative Dentistry and Endodontics, Kathmandu Medical College and Teaching Hospital, Duwakot, Kathmandu, Nepal.

Introduction: Tooth wear is described as loss of hard tooth tissue with no occurrence of dental caries or trauma. Basic Erosive Wear Examination, a new scoring system, is a partial scoring system recording the most severely affected surface in a sextant and the cumulative score guides the management of the condition for the practitioner. The objectives of this study were to determine the prevalence of tooth wear and its association with its risk factors like gender, oral hygiene, diet, general health and life style. Read More

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November 2018
1 Read

The effect of aspartame and pH changes on the erosive potential of cola drinks in bovine enamel: An in vitro study.

J Clin Exp Dent 2018 Sep 1;10(9):e933-e937. Epub 2018 Sep 1.

Departments of Pediatric Dentistry, Orthodontics and Public Health.

Background: The aim of this study was to clarify the mechanism behind the different erosive potential of regular and light cola drinks: pH difference and/or aspartame presence.

Material And Methods: Sixty bovine enamel blocks were randomly divided into 5 groups: RC - regular cola, RCpH - addition of base to increase regular cola pH, RCAS - addition of aspartame to regular cola, LC - light cola, and LCpH - addition of acid to decrease light cola pH. Two-thirds of the blocks surface was coated with nail varnish for reference. Read More

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September 2018
4 Reads

Clinical Validity and Reliability of the Malay Language Translations of Gastroesophageal Reflux Disease Questionnaire and Quality of Life in Reflux and Dyspepsia Questionnaire in a Primary Care Setting.

Dig Dis 2018 Nov 1:1-8. Epub 2018 Nov 1.

School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Malaysia.

Background: Gastroesophageal Reflux Disease Questionnaire (GERDQ) and Quality of Life in Reflux and Dyspepsia Questionnaire (QOLRAD) are reliable tools for evaluation of GERD.

Aim: We aimed to test validity and reliability of Malay language translations of GERDQ and QOLRAD in a primary care setting.

Methods: The questionnaires were first translated into the Malay language (GERDQ-M and QOLRAD-M). Read More

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November 2018
9 Reads

ACVIM consensus statement: Support for rational administration of gastrointestinal protectants to dogs and cats.

J Vet Intern Med 2018 Nov 31;32(6):1823-1840. Epub 2018 Oct 31.

Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Texas A & M University, College Station, Texas.

The gastrointestinal (GI) mucosal barrier is continuously exposed to noxious toxins, reactive oxygen species, microbes, and drugs, leading to the development of inflammatory, erosive, and ultimately ulcerative lesions. This report offers a consensus opinion on the rational administration of GI protectants to dogs and cats, with an emphasis on proton pump inhibitors (PPIs), histamine type-2 receptor antagonists (H RAs), misoprostol, and sucralfate. These medications decrease gastric acidity or promote mucosal protective mechanisms, transforming the management of dyspepsia, peptic ulceration, and gastroesophageal reflux disease. Read More

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November 2018
7 Reads

Influence of Er,Cr:YSGG laser, associated or not to desensitizing agents, in the prevention of acid erosion in bovine root dentin.

Lasers Med Sci 2018 Oct 29. Epub 2018 Oct 29.

School of Dentistry, University of Uberaba, Uberaba, MG, Brazil.

This in vitro study evaluated the influence of the Er,Cr:YSGG laser, associated or not to desensitizing agents, in the prevention of acid erosion in bovine root dentin. Eighty dentin specimens were selected and divided into eight groups (n = 10): G1: negative control; G2: positive control (5% fluoride varnish-FV); G3: Er,Cr:YSGG laser; G4: FV + laser; G5: 3% potassium oxalate; G6: 3% potassium oxalate + laser; G7: biphasic calcium silicate/phosphate gel (gel); G8: gel + laser. Laser parameters: 0. Read More

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October 2018
3 Reads

Clinical, endoscopic, and histologic characteristics of lymphocytic esophagitis: a systematic review.

Esophagus 2018 Oct 29. Epub 2018 Oct 29.

Division of Gastroenterology, St. Michael's Hospital, Department of Medicine, University of Toronto, St. Michael's Hospital, 30 Bond Street, 16-036 Cardinal Carter Wing, Toronto, ON, M5B 1W8, Canada.

Objective: Lymphocytic esophagitis (LyE) is a novel, yet poorly described, clinicopathologic entity. The aim of this systematic review was to characterize the demographic, clinical, endoscopic, and histologic features of LyE in observational studies of adult and pediatric patients.

Design: We searched the Embase, MEDLINE, and SCOPUS databases for relevant studies in 2018. Read More

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October 2018
6 Reads
0.740 Impact Factor

Oral Lichenoid Lesion Manifesting as Desquamative Gingivitis: Unlikely Association? Case Report.

Open Dent J 2018 28;12:679-686. Epub 2018 Sep 28.

Department of Pathology, Faculty of Dentistry, Cesmac University Center, Cônego Machado, 918, Farol CEP: 57051-160, Maceió, Alagoas, Brazil.

Introduction: The aim of this report is to present a clinical case of oral lichenoid lesions associated with amalgam restorations with the presence of desquamative gingivitis for a nine months follow up period.

Case Report: The histopathologic characteristics and direct immunofluorescence were compatible with Oral Lichenoid Lesion (LLO). Diagnosis was based on a synthesis of all available information, including medical history, clinical examination, histopathology and the results of specific tests, such as the patch test, which confirmed allergy to thimerosal, an organic compound of mercury. Read More

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September 2018
1 Read

Mechanical and surface properties analysis of restorative materials submitted to erosive challenges .

Eur J Dent 2018 Oct-Dec;12(4):559-565

Department of Dental Materials and Prosthodontics, Araçatuba School of Dentistry, UNESP - São Paulo State University, Araçatuba, São Paulo, Brazil.

Objective: This study aims to evaluate the effect of acidic solutions (AS) on surface roughness (Ra) and microhardness of restorative materials (RM).

Materials And Methods: Eight volunteers wore intraoral palatal devices (IPD) containing samples of RM: Ketac Nano (KN); Ketac Nano + Biscover LV (KN-B); Esthet-X (EX); Esthet-X + Biscover LV (EX-B); Supreme XT (SXT); Supreme XT + Biscover LV (SXT-B); and bovine enamel. The samples were submitted to three phases: (1) immersion in 0. Read More

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October 2018
6 Reads

Necrotizing fasciitis of chest and right abdominal wall caused by acute perforated appendicitis: Case report.

Int J Surg Case Rep 2018 Oct 4;53:32-34. Epub 2018 Oct 4.

Department of Anesthesiology and Critical Care Medicine, Burns and Trauma Center, Ben Arous, Tunisia. Electronic address:

Introduction: Necrotizing fasciitis is an uncommon infection characterized by a necrotic infection that rapidly diffuse along the fascia and progresses to systemic sepsis. The combined occurrence of necrotizing fasciitis of the chest wall and acute appendicitis is extremely unusual.

Case Presentation: A 27-year-old man without any significant medical history presented to the emergency department, in the postoperative course of a laparotomy for perforated acute appendicitis, with septic shock and a large erythematous region over the right abdominal wall. Read More

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October 2018
4 Reads

[Allopurinol-induced DRESS syndrome: Drug Reaction with Eosynophilia and Systemic Symptoms (DRESS)].

Pan Afr Med J 2018 12;30:120. Epub 2018 Jun 12.

Service de Dermatologie, HMIMV Rabat, Maroc.

We report the case of a 60-year old patient with a 1-month history of hyperuricemia treated with allopurinol. The patient presented to the Department of Dermatology with acute rash on the face and the lower limbs associated with fever, arthralgias and myalgias. Clinical examination showed symmetric macular erythema on the face at the level of the cheeks with discreet edema (A), erythematous plaques at the level of both legs with healthy skin areas extending progressively from the bottom-up. Read More

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November 2018
5 Reads

Anti-Erosive Effect of Solutions Containing Sodium Fluoride, Stannous Chloride, and Selected Film-Forming Polymers.

Caries Res 2018 Oct 25;53(3):305-313. Epub 2018 Oct 25.

Department of Restorative Dentistry, School of Dentistry, University of São Paulo, São Paulo, Brazil.

The aim of this study was to evaluate the anti-erosive effect of solutions containing sodium fluoride (F: 225 ppm F-), stannous chloride (Sn: 800 ppm Sn2+), and some film-forming polymers (Gantrez: Poly [methylvinylether-alt-maleic anhydride]; PGA: propylene glycol alginate; Plasdone: poly[vinylpyrrolidone]; and CMC: carboxymethylcellulose). Solutions were tested in an erosion-remineralization cycling model, using enamel and dentin specimens (n = 10, for each substrate). Distilled water was the negative control. Read More

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October 2018